SIMILAR PATTERNS OF AMINO ACIDS FOR 6ECF_I_DVAI3010_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cpt CYTOCHROME P450-TERP

(Pseudomonas sp.) 		PF00067
(p450) 		3 PHE A 352
ARG A 366
ALA A  58
 None
 0.75A 6ecfB-1cptA:
undetectable		 6ecfB-1cptA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dk5 ANNEXIN 24(CA32)

(Capsicum annuum) 		PF00191
(Annexin) 		3 PHE A 252
ARG A 272
ALA A 240
 None
SO4  A 809 (-4.5A)
None
 0.93A 6ecfB-1dk5A:
undetectable		 6ecfB-1dk5A:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dyo ENDO-1,4-BETA-XYLANA
SE Y

(Ruminiclostridium
thermocellum) 		PF02018
(CBM_4_9) 		3 PHE A  88
ARG A  49
ALA A  83
 None
 0.86A 6ecfB-1dyoA:
undetectable		 6ecfB-1dyoA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fnn CELL DIVISION
CONTROL PROTEIN 6

(Pyrobaculum
aerophilum) 		PF09079
(Cdc6_C)
PF13401
(AAA_22) 		3 PHE A 144
ARG A 108
ALA A 137
 None
 0.87A 6ecfB-1fnnA:
undetectable		 6ecfB-1fnnA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1w ISOCITRATE
DEHYDROGENASE

(Azotobacter
vinelandii) 		PF03971
(IDH) 		3 PHE A 733
ARG A 728
ALA A  28
 None
 0.99A 6ecfB-1j1wA:
undetectable		 6ecfB-1j1wA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhy METHANE
MONOOXYGENASE
HYDROXYLASE
METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylosinus
trichosporium;
Methylosinus
trichosporium) 		PF02332
(Phenol_Hydrox)
PF02964
(MeMO_Hyd_G) 		3 PHE G 129
ARG B  83
ALA G 135
 None
 0.93A 6ecfB-1mhyG:
undetectable		 6ecfB-1mhyG:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mw9 DNA TOPOISOMERASE I

(Escherichia
coli) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		3 PHE X 284
ARG X 296
ALA X 400
 None
 0.96A 6ecfB-1mw9X:
3.8		 6ecfB-1mw9X:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nfd N15 ALPHA-BETA
T-CELL RECEPTOR
N15 ALPHA-BETA
T-CELL RECEPTOR

(Mus musculus;
Mus musculus) 		PF07686
(V-set)
PF09291
(DUF1968)
PF07654
(C1-set)
PF07686
(V-set) 		3 PHE A 146
ARG B 195
ALA A 116
 None
 0.77A 6ecfB-1nfdA:
undetectable		 6ecfB-1nfdA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nld FAB1583

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 PHE H 146
ARG H  87
ALA H 168
 None
 0.96A 6ecfB-1nldH:
undetectable		 6ecfB-1nldH:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nmy SIMILAR TO
THYMIDYLATE KINASE
(DTMP KINASE)

(Homo sapiens) 		PF02223
(Thymidylate_kin) 		3 PHE A 164
ARG A  97
ALA A  17
 None
FDM  A 301 ( 3.4A)
ADP  A 302 ( 4.4A)
 0.88A 6ecfB-1nmyA:
2.1		 6ecfB-1nmyA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qqg INSULIN RECEPTOR
SUBSTRATE 1

(Homo sapiens) 		PF00169
(PH)
PF02174
(IRS) 		3 PHE A  70
ARG A 184
ALA A  85
 None
 0.94A 6ecfB-1qqgA:
undetectable		 6ecfB-1qqgA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r24 PROTEIN (IGG3-KAPPA
ANTIBODY (HEAVY
CHAIN))

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 PHE B  68
ARG B  87
ALA B  40
 None
 0.80A 6ecfB-1r24B:
undetectable		 6ecfB-1r24B:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r24 PROTEIN (IGG3-KAPPA
ANTIBODY (HEAVY
CHAIN))

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 PHE B  68
ARG B  87
ALA B  92
 None
 0.95A 6ecfB-1r24B:
undetectable		 6ecfB-1r24B:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8w GLYCEROL DEHYDRATASE

(Clostridium
butyricum) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 PHE A 306
ARG A  12
ALA A 240
 None
 0.99A 6ecfB-1r8wA:
2.3		 6ecfB-1r8wA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb3 4-HYDROXYBENZOYL-COA
REDUCTASE ALPHA
SUBUNIT
4-HYDROXYBENZOYL-COA
REDUCTASE GAMMA
SUBUNIT

(Thauera
aromatica;
Thauera
aromatica) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2)
PF00111
(Fer2)
PF01799
(Fer2_2) 		3 PHE C 102
ARG C  29
ALA A 195
 None
 0.84A 6ecfB-1sb3C:
undetectable		 6ecfB-1sb3C:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb7 TRNA PSEUDOURIDINE
SYNTHASE D

(Escherichia
coli) 		PF01142
(TruD) 		3 PHE A 234
ARG A 247
ALA A 228
 None
 0.98A 6ecfB-1sb7A:
undetectable		 6ecfB-1sb7A:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1snn 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE

(Methanocaldococcus
jannaschii) 		PF00926
(DHBP_synthase) 		3 PHE A  70
ARG A 161
ALA A  57
 None
5RP  A 401 (-3.1A)
None
 0.69A 6ecfB-1snnA:
undetectable		 6ecfB-1snnA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vqz LIPOATE-PROTEIN
LIGASE, PUTATIVE

(Streptococcus
pneumoniae) 		PF03099
(BPL_LplA_LipB)
PF10437
(Lip_prot_lig_C) 		3 PHE A 279
ARG A  45
ALA A 287
 None
 0.96A 6ecfB-1vqzA:
undetectable		 6ecfB-1vqzA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wl7 ARABINANASE-TS

(Geobacillus
thermodenitrificans) 		PF04616
(Glyco_hydro_43) 		3 PHE A 104
ARG A 223
ALA A 199
 None
 0.94A 6ecfB-1wl7A:
undetectable		 6ecfB-1wl7A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ykd ADENYLATE CYCLASE

(Anabaena sp.) 		PF01590
(GAF) 		3 PHE A 156
ARG A 161
ALA A 181
 None
 0.81A 6ecfB-1ykdA:
undetectable		 6ecfB-1ykdA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ag5 DEHYDROGENASE/REDUCT
ASE (SDR FAMILY)
MEMBER 6

(Homo sapiens) 		PF13561
(adh_short_C2) 		3 PHE A 202
ARG A 188
ALA A 135
 SO4  A5001 (-4.1A)
SO4  A5001 (-3.6A)
None
 0.76A 6ecfB-2ag5A:
4.2		 6ecfB-2ag5A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0t NADP ISOCITRATE
DEHYDROGENASE

(Corynebacterium
glutamicum) 		PF03971
(IDH) 		3 PHE A 729
ARG A 724
ALA A  26
 None
 0.93A 6ecfB-2b0tA:
undetectable		 6ecfB-2b0tA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2i AMMONIUM TRANSPORTER

(Archaeoglobus
fulgidus) 		PF00909
(Ammonium_transp) 		3 PHE A 177
ARG A 290
ALA A 109
 None
 0.98A 6ecfB-2b2iA:
undetectable		 6ecfB-2b2iA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bov MONO-ADP-RIBOSYLTRAN
SFERASE C3

(Clostridium
botulinum) 		PF03496
(ADPrib_exo_Tox) 		3 PHE B1183
ARG B1128
ALA B1210
 None
 0.86A 6ecfB-2bovB:
undetectable		 6ecfB-2bovB:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bvt BETA-1,4-MANNANASE

(Cellulomonas
fimi) 		PF02156
(Glyco_hydro_26) 		3 PHE A 239
ARG A 396
ALA A 371
 None
 0.89A 6ecfB-2bvtA:
2.8		 6ecfB-2bvtA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dr3 UPF0273 PROTEIN
PH0284

(Pyrococcus
horikoshii) 		PF06745
(ATPase) 		3 PHE A  86
ARG A  67
ALA A  58
 None
 0.93A 6ecfB-2dr3A:
undetectable		 6ecfB-2dr3A:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ewo PUTATIVE AGMATINE
DEIMINASE

(Streptococcus
mutans) 		PF04371
(PAD_porph) 		3 PHE A  21
ARG A 231
ALA A 236
 None
 0.96A 6ecfB-2ewoA:
undetectable		 6ecfB-2ewoA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gfp MULTIDRUG RESISTANCE
PROTEIN D

(Escherichia
coli) 		PF07690
(MFS_1) 		3 PHE A 328
ARG A 118
ALA A 306
 None
 0.87A 6ecfB-2gfpA:
undetectable		 6ecfB-2gfpA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m99 PROTEASE INHIBITOR
NACI

(Naja atra) 		PF00014
(Kunitz_BPTI) 		3 PHE A  33
ARG A  44
ALA A  16
 None
 0.99A 6ecfB-2m99A:
undetectable		 6ecfB-2m99A:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pef SERINE PROTEASE
INHIBITOR

(Caldanaerobacter
subterraneus) 		PF00079
(Serpin) 		3 PHE A 246
ARG A 399
ALA A 276
 None
 0.99A 6ecfB-2pefA:
undetectable		 6ecfB-2pefA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pi5 DNA-DIRECTED RNA
POLYMERASE

(Escherichia
virus T7) 		PF00940
(RNA_pol)
PF14700
(RPOL_N) 		3 PHE A 268
ARG A 143
ALA A 295
 None
 0.93A 6ecfB-2pi5A:
undetectable		 6ecfB-2pi5A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pql D7R4 PROTEIN

(Anopheles
gambiae) 		PF01395
(PBP_GOBP) 		3 PHE A 110
ARG A  22
ALA A 118
 TSS  A 145 (-4.4A)
TSS  A 145 (-3.5A)
None
 0.90A 6ecfB-2pqlA:
undetectable		 6ecfB-2pqlA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qpv UNCHARACTERIZED
PROTEIN ATU1531

(Agrobacterium
fabrum) 		no annotation 3 PHE A  23
ARG A  32
ALA A 133
 None
 0.97A 6ecfB-2qpvA:
undetectable		 6ecfB-2qpvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2reb REC A

(Escherichia
coli) 		PF00154
(RecA) 		3 PHE A 270
ARG A 324
ALA A  82
 None
 0.70A 6ecfB-2rebA:
undetectable		 6ecfB-2rebA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yr0 HYPOTHETICAL PROTEIN
TTHA0223

(Thermus
thermophilus) 		PF08241
(Methyltransf_11) 		3 PHE A 249
ARG A 202
ALA A 144
 None
 0.84A 6ecfB-2yr0A:
3.3		 6ecfB-2yr0A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c7k REGULATOR OF
G-PROTEIN SIGNALING
16

(Mus musculus) 		PF00615
(RGS) 		3 PHE B 117
ARG B 136
ALA B 154
 None
 0.90A 6ecfB-3c7kB:
undetectable		 6ecfB-3c7kB:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmt PROTEIN RECA

(Escherichia
coli) 		PF00154
(RecA) 		3 PHE A4270
ARG A4324
ALA A4082
 None
 0.93A 6ecfB-3cmtA:
undetectable		 6ecfB-3cmtA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmv PROTEIN RECA

(Escherichia
coli) 		PF00154
(RecA) 		3 PHE A2270
ARG A2324
ALA A2082
 None
 0.78A 6ecfB-3cmvA:
undetectable		 6ecfB-3cmvA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmv PROTEIN RECA

(Escherichia
coli) 		PF00154
(RecA) 		3 PHE A3270
ARG A3324
ALA A3082
 None
 0.94A 6ecfB-3cmvA:
undetectable		 6ecfB-3cmvA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dty OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY

(Pseudomonas
syringae group
genomosp. 3) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 PHE A  46
ARG A  30
ALA A  91
 None
 0.88A 6ecfB-3dtyA:
4.0		 6ecfB-3dtyA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e6q PUTATIVE
5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
ISOMERASE

(Pseudomonas
aeruginosa) 		PF02962
(CHMI) 		3 PHE A  35
ARG A  72
ALA A  79
 None
 0.70A 6ecfB-3e6qA:
undetectable		 6ecfB-3e6qA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fao NON-STRUCTURAL
PROTEIN

(Porcine
reproductive
and respiratory
syndrome virus) 		PF05579
(Peptidase_S32) 		3 PHE A 112
ARG A  90
ALA A 195
 None
 0.80A 6ecfB-3faoA:
undetectable		 6ecfB-3faoA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fb2 SPECTRIN ALPHA
CHAIN, BRAIN
SPECTRIN

(Homo sapiens) 		PF00435
(Spectrin) 		3 PHE A1450
ARG A1525
ALA A1457
 None
 0.80A 6ecfB-3fb2A:
undetectable		 6ecfB-3fb2A:
27.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcy XYLAN ESTERASE 1

(Thermoanaerobacterium
saccharolyticum) 		PF05448
(AXE1) 		3 PHE A  24
ARG A 259
ALA A  31
 None
 0.76A 6ecfB-3fcyA:
11.1		 6ecfB-3fcyA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fg2 PUTATIVE RUBREDOXIN
REDUCTASE

(Rhodopseudomonas
palustris) 		PF07992
(Pyr_redox_2)
PF14759
(Reductase_C) 		3 PHE P  61
ARG P  42
ALA P 105
 None
FAD  P 449 (-3.7A)
FAD  P 449 (-4.7A)
 0.84A 6ecfB-3fg2P:
undetectable		 6ecfB-3fg2P:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		3 PHE A   6
ARG A 418
ALA B1146
 None
 0.96A 6ecfB-3h0gA:
undetectable		 6ecfB-3h0gA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lou FORMYLTETRAHYDROFOLA
TE DEFORMYLASE

(Burkholderia
mallei) 		PF00551
(Formyl_trans_N) 		3 PHE A 275
ARG A 194
ALA A  87
 None
None
EDO  A 298 (-3.9A)
 0.89A 6ecfB-3louA:
3.8		 6ecfB-3louA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Encephalitozoon
cuniculi) 		PF00274
(Glycolytic) 		3 PHE A  53
ARG A  37
ALA A  26
 None
2FP  A 345 ( 4.9A)
2FP  A 345 (-3.4A)
 0.85A 6ecfB-3mbfA:
2.4		 6ecfB-3mbfA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mpn TRANSPORTER

(Aquifex
aeolicus) 		PF00209
(SNF) 		3 PHE A 331
ARG A 212
ALA A 223
 None
 0.92A 6ecfB-3mpnA:
undetectable		 6ecfB-3mpnA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mpn TRANSPORTER

(Aquifex
aeolicus) 		PF00209
(SNF) 		3 PHE A 331
ARG A 212
ALA A 304
 None
 0.76A 6ecfB-3mpnA:
undetectable		 6ecfB-3mpnA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q8x ANTIDOTE OF
EPSILON-ZETA
POSTSEGREGATIONAL
KILLING SYSTEM
ZETA-TOXIN

(Streptococcus
pyogenes;
Streptococcus
pyogenes) 		PF08998
(Epsilon_antitox)
PF06414
(Zeta_toxin) 		3 PHE B  76
ARG B 171
ALA A  19
 None
 0.98A 6ecfB-3q8xB:
2.8		 6ecfB-3q8xB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rrk V-TYPE ATPASE 116
KDA SUBUNIT

(Meiothermus
ruber) 		no annotation 3 PHE A 163
ARG A 152
ALA A 176
 None
 0.94A 6ecfB-3rrkA:
undetectable		 6ecfB-3rrkA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3saj GLUTAMATE RECEPTOR 1

(Rattus
norvegicus) 		PF01094
(ANF_receptor) 		3 PHE A 328
ARG A 343
ALA A 273
 None
 0.92A 6ecfB-3sajA:
3.1		 6ecfB-3sajA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sdo NITRILOTRIACETATE
MONOOXYGENASE

(Burkholderia
pseudomallei) 		PF00296
(Bac_luciferase) 		3 PHE A 367
ARG A 380
ALA A 242
 None
 0.92A 6ecfB-3sdoA:
undetectable		 6ecfB-3sdoA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t8l ADENINE DEAMINASE 2

(Agrobacterium
fabrum) 		PF01979
(Amidohydro_1)
PF13382
(Adenine_deam_C) 		3 PHE A 419
ARG A 220
ALA A 560
 None
 0.87A 6ecfB-3t8lA:
undetectable		 6ecfB-3t8lA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uk1 TRANSKETOLASE

(Burkholderia
thailandensis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		3 PHE A 549
ARG A 552
ALA A 525
 None
 0.93A 6ecfB-3uk1A:
undetectable		 6ecfB-3uk1A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ukf UDP-GALACTOPYRANOSE
MUTASE

(Aspergillus
fumigatus) 		PF13450
(NAD_binding_8) 		3 PHE A  72
ARG A 211
ALA A  79
 None
 0.89A 6ecfB-3ukfA:
undetectable		 6ecfB-3ukfA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vx6 E1

(Kluyveromyces
marxianus) 		PF16420
(ATG7_N) 		3 PHE A  49
ARG A 233
ALA A   8
 None
 0.79A 6ecfB-3vx6A:
undetectable		 6ecfB-3vx6A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdr ALCOHOL
DEHYDROGENASE DOMAIN
OF THE BIFUNCTIONAL
ACETALDEHYDE
DEHYDROGENASE

(Parageobacillus
thermoglucosidasius) 		PF00465
(Fe-ADH) 		3 PHE A 829
ARG A 863
ALA A 837
 None
 0.89A 6ecfB-3zdrA:
5.2		 6ecfB-3zdrA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c0j MITOCHONDRIAL RHO
GTPASE

(Drosophila
melanogaster) 		PF00071
(Ras)
PF08355
(EF_assoc_1)
PF08356
(EF_assoc_2) 		3 PHE A 415
ARG A 330
ALA A 337
 None
 0.99A 6ecfB-4c0jA:
4.1		 6ecfB-4c0jA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewg BETA-KETOACYL
SYNTHASE

(Paraburkholderia
phymatum) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 PHE A  90
ARG A 100
ALA A 248
 None
 0.90A 6ecfB-4ewgA:
undetectable		 6ecfB-4ewgA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g09 HISTIDINOL
DEHYDROGENASE

(Brucella suis) 		PF00815
(Histidinol_dh) 		3 PHE A  12
ARG A 323
ALA A  18
 None
 0.98A 6ecfB-4g09A:
undetectable		 6ecfB-4g09A:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k2a HALOALKANE
DEHALOGENASE

(Bradyrhizobium
elkanii) 		PF00561
(Abhydrolase_1) 		3 PHE A 151
ARG A 170
ALA A 143
 None
 0.88A 6ecfB-4k2aA:
16.5		 6ecfB-4k2aA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kr9 PROBABLE TRNA
SULFURTRANSFERASE

(Thermotoga
maritima) 		PF02568
(ThiI)
PF02926
(THUMP) 		3 PHE A 268
ARG A 313
ALA A 282
 None
 0.94A 6ecfB-4kr9A:
undetectable		 6ecfB-4kr9A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lub PUTATIVE PREPHENATE
DEHYDRATASE

(Streptococcus
mutans) 		PF00800
(PDT) 		3 PHE A  68
ARG A 177
ALA A  79
 None
 0.99A 6ecfB-4lubA:
undetectable		 6ecfB-4lubA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Methanocaldococcus
jannaschii) 		PF02350
(Epimerase_2) 		3 PHE A 348
ARG A 311
ALA A 150
 None
 0.94A 6ecfB-4nesA:
5.2		 6ecfB-4nesA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5p UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF09994
(DUF2235) 		3 PHE A 773
ARG A 720
ALA A 293
 None
 0.77A 6ecfB-4o5pA:
7.1		 6ecfB-4o5pA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4onu ACETYLTRANSFERASE
PAT

(Mycolicibacterium
smegmatis) 		PF00027
(cNMP_binding)
PF13302
(Acetyltransf_3) 		3 PHE A 139
ARG A 135
ALA A  97
 None
 0.94A 6ecfB-4onuA:
undetectable		 6ecfB-4onuA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ptf DNA POLYMERASE
EPSILON CATALYTIC
SUBUNIT A

(Saccharomyces
cerevisiae) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		3 PHE A 140
ARG A 252
ALA A 524
 None
 0.98A 6ecfB-4ptfA:
undetectable		 6ecfB-4ptfA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tkt AT-LESS POLYKETIDE
SYNTHASE

(Streptomyces
platensis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 PHE A3214
ARG A3247
ALA A3640
 None
CL  A4001 (-4.4A)
None
 0.98A 6ecfB-4tktA:
undetectable		 6ecfB-4tktA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tpn PUTATIVE P450-LIKE
PROTEIN

(Streptomyces
scabiei) 		PF00067
(p450) 		3 PHE A 331
ARG A 346
ALA A  44
 None
 0.88A 6ecfB-4tpnA:
undetectable		 6ecfB-4tpnA:
25.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9i PERIPLASMIC [NIFE]
HYDROGENASE LARGE
SUBUNIT
PERIPLASMIC [NIFE]
HYDROGENASE SMALL
SUBUNIT

(Desulfovibrio
vulgaris;
Desulfovibrio
vulgaris) 		PF00374
(NiFeSe_Hases)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C) 		3 PHE L 191
ARG L  32
ALA S  55
 None
 0.96A 6ecfB-4u9iL:
undetectable		 6ecfB-4u9iL:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uvk ZYRO0D15994P

(Zygosaccharomyces
rouxii) 		PF08514
(STAG) 		3 PHE A 941
ARG A1005
ALA A 949
 None
 0.99A 6ecfB-4uvkA:
undetectable		 6ecfB-4uvkA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x28 ACYL-COA
DEHYDROGENASE
ACYL-COA
DEHYDROGENASE

(Mycobacterium
tuberculosis;
Mycobacterium
tuberculosis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
no annotation 		3 PHE D 352
ARG A 339
ALA D 322
 None
 0.96A 6ecfB-4x28D:
undetectable		 6ecfB-4x28D:
26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ceg PLASMID
STABILIZATION SYSTEM

(Mesorhizobium
opportunistum) 		PF05016
(ParE_toxin) 		3 PHE B  69
ARG B  96
ALA B  29
 GOL  B 202 ( 4.8A)
GOL  B 201 ( 3.6A)
None
 0.81A 6ecfB-5cegB:
undetectable		 6ecfB-5cegB:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3i HISTIDINE--TRNA
LIGASE

(Acinetobacter
baumannii) 		PF03129
(HGTP_anticodon)
PF13393
(tRNA-synt_His) 		3 PHE A 429
ARG A 331
ALA A 409
 None
 0.86A 6ecfB-5e3iA:
2.1		 6ecfB-5e3iA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gai TAIL FIBER PROTEIN

(Salmonella
virus P22) 		no annotation 3 PHE Y 243
ARG Y 357
ALA Y 460
 None
 0.87A 6ecfB-5gaiY:
undetectable		 6ecfB-5gaiY:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h42 UNCHARACTERIZED
PROTEIN

(Lachnoclostridium
phytofermentans) 		PF17167
(Glyco_hydro_36) 		3 PHE A 193
ARG A  55
ALA A 185
 None
 0.97A 6ecfB-5h42A:
undetectable		 6ecfB-5h42A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb3 NUCLEOPORIN NIC96

(Chaetomium
thermophilum) 		PF04097
(Nic96) 		3 PHE A 499
ARG A 533
ALA A 556
 None
 0.92A 6ecfB-5hb3A:
undetectable		 6ecfB-5hb3A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hp5 PROTEIN-ARGININE
DEIMINASE TYPE-1

(Homo sapiens) 		PF03068
(PAD)
PF08526
(PAD_N)
PF08527
(PAD_M) 		3 PHE A 370
ARG A 396
ALA A 454
 None
 0.73A 6ecfB-5hp5A:
undetectable		 6ecfB-5hp5A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ibx TRIOSEPHOSPHATE
ISOMERASE

(Streptococcus
pneumoniae) 		PF00121
(TIM) 		3 PHE A 143
ARG A 100
ALA A 150
 None
 0.97A 6ecfB-5ibxA:
undetectable		 6ecfB-5ibxA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens) 		PF11386
(VERL)
PF13416
(SBP_bac_8) 		3 PHE A4060
ARG A4081
ALA A4005
 None
 0.89A 6ecfB-5ii5A:
undetectable		 6ecfB-5ii5A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kn8 ADENINE DNA
GLYCOSYLASE

(Geobacillus
stearothermophilus) 		PF00633
(HHH)
PF00730
(HhH-GPD) 		3 PHE A  21
ARG A  31
ALA A 195
 None
 0.99A 6ecfB-5kn8A:
undetectable		 6ecfB-5kn8A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lo9 CYTOCHROME C

(Marichromatium
purpuratum) 		PF00034
(Cytochrom_C)
PF13442
(Cytochrome_CBB3) 		3 PHE A  55
ARG A 159
ALA A  38
 None
HEC  A1002 ( 3.4A)
HEC  A1001 (-3.6A)
 0.89A 6ecfB-5lo9A:
undetectable		 6ecfB-5lo9A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m45 ACETONE CARBOXYLASE
BETA SUBUNIT

(Xanthobacter
autotrophicus) 		PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		3 PHE B  34
ARG B 710
ALA B 497
 None
 0.95A 6ecfB-5m45B:
4.4		 6ecfB-5m45B:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n8o DNA HELICASE I

(Escherichia
coli) 		PF07057
(TraI)
PF08751
(TrwC)
PF13604
(AAA_30) 		3 PHE A 587
ARG A 717
ALA A 786
 None
 0.71A 6ecfB-5n8oA:
undetectable		 6ecfB-5n8oA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nbs BETA-GLUCOSIDASE

(Neurospora
crassa) 		no annotation 3 PHE A 269
ARG A 332
ALA A  33
 None
 0.95A 6ecfB-5nbsA:
3.1		 6ecfB-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oar BETA-HEXOSAMINIDASE

(Aspergillus
oryzae) 		no annotation 3 PHE B 453
ARG B 193
ALA B 305
 None
NGT  B 707 (-3.0A)
None
 0.85A 6ecfB-5oarB:
undetectable		 6ecfB-5oarB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb DNA REPLICATION
LICENSING FACTOR
MCM3
CELL DIVISION
CONTROL PROTEIN 6

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF17207
(MCM_OB)
PF09079
(Cdc6_C)
PF13401
(AAA_22) 		3 PHE 9 319
ARG 3 847
ALA 9 391
 None
 0.88A 6ecfB-5udb9:
undetectable		 6ecfB-5udb9:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB

(Staphylococcus
sp. HMSC055H04) 		no annotation 3 PHE A  52
ARG A 102
ALA A  59
 None
 0.98A 6ecfB-5wk0A:
undetectable		 6ecfB-5wk0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7u TREHALOSE SYNTHASE

(Thermobaculum
terrenum) 		no annotation 3 PHE A 505
ARG A 464
ALA A 475
 None
 0.99A 6ecfB-5x7uA:
undetectable		 6ecfB-5x7uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnc -

(-) 		no annotation 3 PHE A 187
ARG A 118
ALA A 165
 None
 0.88A 6ecfB-5xncA:
undetectable		 6ecfB-5xncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xup TELOMERIC
REPEAT-BINDING
FACTOR 1

(Homo sapiens) 		no annotation 3 PHE A  81
ARG A  88
ALA A 261
 None
 0.97A 6ecfB-5xupA:
undetectable		 6ecfB-5xupA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6q ALDEHYDE OXIDASE
LARGE SUBUNIT

(Methylobacillus
sp. KY4400) 		no annotation 3 PHE C 164
ARG C 204
ALA C  73
 None
 0.96A 6ecfB-5y6qC:
undetectable		 6ecfB-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yfb DIPEPTIDYL PEPTIDASE
3

(Armillaria
tabescens) 		no annotation 3 PHE A 115
ARG A 566
ALA A 383
 None
 0.92A 6ecfB-5yfbA:
undetectable		 6ecfB-5yfbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yy0 CYTOSOLIC
NIFE-HYDROGENASE,
ALPHA SUBUNIT

(Thermococcus
kodakarensis) 		no annotation 3 PHE A 317
ARG A 275
ALA A  71
 None
 0.83A 6ecfB-5yy0A:
undetectable		 6ecfB-5yy0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c66 CRISPR-ASSOCIATED
HELICASE, CAS3
FAMILY

(Thermobifida
fusca) 		no annotation 3 PHE G 944
ARG G 884
ALA G 595
 None
 0.60A 6ecfB-6c66G:
undetectable		 6ecfB-6c66G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cv0 SPIKE GLYCOPROTEIN

(Avian
coronavirus) 		no annotation 3 PHE A 573
ARG A 920
ALA A 986
 None
 0.76A 6ecfB-6cv0A:
undetectable		 6ecfB-6cv0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dch SCOE PROTEIN

(Streptomyces
coeruleorubidus) 		no annotation 3 PHE A  48
ARG A  89
ALA A  56
 None
 0.92A 6ecfB-6dchA:
undetectable		 6ecfB-6dchA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 8
NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13

(Mus musculus;
Mus musculus) 		no annotation
no annotation 		3 PHE X  42
ARG Z  80
ALA X  66
 None
 0.90A 6ecfB-6g72X:
undetectable		 6ecfB-6g72X:
undetectable