SIMILAR PATTERNS OF AMINO ACIDS FOR 6EBZ_D_DAHD123

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a7j PHOSPHORIBULOKINASE

(Rhodobacter
sphaeroides)
PF00485
(PRK)
5 PHE A  84
GLY A  88
ILE A   7
PHE A  44
ILE A  39
None
0.84A 6ebzD-1a7jA:
undetectable
6ebzD-1a7jA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ecx AMINOTRANSFERASE

(Thermotoga
maritima)
PF00266
(Aminotran_5)
5 PHE A 299
GLY A 304
ILE A 349
ILE A 369
ILE A 372
None
1.06A 6ebzD-1ecxA:
undetectable
6ebzD-1ecxA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eww ANTIFREEZE PROTEIN

(Choristoneura
fumiferana)
PF05264
(CfAFP)
5 PHE A  87
SER A  52
GLY A  54
ILE A  82
ILE A  64
None
1.01A 6ebzD-1ewwA:
undetectable
6ebzD-1ewwA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8r L-AMINO ACID OXIDASE

(Calloselasma
rhodostoma)
PF01593
(Amino_oxidase)
5 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
None
1.00A 6ebzD-1f8rA:
undetectable
6ebzD-1f8rA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE


(Pagrus major)
PF00868
(Transglut_N)
PF00927
(Transglut_C)
PF01841
(Transglut_core)
5 PHE A 189
LEU A 192
ASP A 205
GLY A  63
ILE A 105
None
1.06A 6ebzD-1g0dA:
undetectable
6ebzD-1g0dA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g71 DNA PRIMASE

(Pyrococcus
furiosus)
PF01896
(DNA_primase_S)
5 SER A  73
GLY A  38
PHE A  39
ILE A  24
ILE A  28
None
1.00A 6ebzD-1g71A:
undetectable
6ebzD-1g71A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8x MYOSIN II HEAVY
CHAIN FUSED TO
ALPHA-ACTININ 3


(Dictyostelium
discoideum)
PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N)
5 LEU A 529
ASP A 530
GLY A 519
ILE A 517
PHE A 466
None
1.07A 6ebzD-1g8xA:
undetectable
6ebzD-1g8xA:
6.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jx2 MYOSIN-2 HEAVY
CHAIN,DYNAMIN-A


(Dictyostelium
discoideum)
PF00063
(Myosin_head)
PF02736
(Myosin_N)
5 LEU A 540
ASP A 541
GLY A 530
ILE A 528
PHE A 477
None
1.00A 6ebzD-1jx2A:
undetectable
6ebzD-1jx2A:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
9 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
None
None
None
MN  A1001 (-2.7A)
None
None
None
None
None
0.49A 6ebzD-1kgpA:
42.2
6ebzD-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
8 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 195
ILE A 198
None
None
None
MN  A1001 (-2.7A)
None
None
None
None
0.58A 6ebzD-1kgpA:
42.2
6ebzD-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ogq POLYGALACTURONASE
INHIBITING PROTEIN


(Phaseolus
vulgaris)
PF08263
(LRRNT_2)
6 LEU A 141
GLY A 170
PHE A 194
PHE A 156
ILE A 154
ILE A 145
None
1.28A 6ebzD-1ogqA:
undetectable
6ebzD-1ogqA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oh9 ACETYLGLUTAMATE
KINASE


(Escherichia
coli)
PF00696
(AA_kinase)
5 PHE A  24
LEU A  23
ILE A  97
ILE A  40
ILE A   7
None
1.06A 6ebzD-1oh9A:
undetectable
6ebzD-1oh9A:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pc3 PHOSPHATE-BINDING
PROTEIN 1


(Mycobacterium
tuberculosis)
PF12849
(PBP_like_2)
6 PHE A 312
LEU A 309
THR A 308
ILE A  58
PHE A  49
ILE A  79
None
1.47A 6ebzD-1pc3A:
undetectable
6ebzD-1pc3A:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pg5 ASPARTATE
CARBAMOYLTRANSFERASE


(Sulfolobus
acidocaldarius)
PF00185
(OTCace)
PF02729
(OTCace_N)
5 LEU A   1
GLY A 298
PHE A  10
ILE A  18
ILE A 292
None
1.07A 6ebzD-1pg5A:
undetectable
6ebzD-1pg5A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN


(Escherichia
coli)
PF00268
(Ribonuc_red_sm)
5 SER A 121
ILE A 125
PHE A 212
ILE A 231
ILE A 234
None
0.71A 6ebzD-1pm2A:
29.0
6ebzD-1pm2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN


(Escherichia
coli)
PF00268
(Ribonuc_red_sm)
5 THR A  81
SER A 121
ILE A 125
ILE A 231
ILE A 234
None
0.50A 6ebzD-1pm2A:
29.0
6ebzD-1pm2A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qqj FUMARYLACETOACETATE
HYDROLASE


(Mus musculus)
PF01557
(FAA_hydrolase)
PF09298
(FAA_hydrolase_N)
5 LEU A 230
GLY A 349
ILE A 351
PHE A 405
ILE A 297
None
CA  A 420 ( 4.5A)
None
None
None
1.00A 6ebzD-1qqjA:
undetectable
6ebzD-1qqjA:
9.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1r2f PROTEIN
(RIBONUCLEOTIDE
REDUCTASE R2)


(Salmonella
enterica)
PF00268
(Ribonuc_red_sm)
9 PHE A  60
LEU A  63
THR A  64
ASP A  67
ILE A 108
PHE A 109
PHE A 166
ILE A 185
ILE A 188
None
None
None
FE  A 400 (-3.0A)
None
None
None
None
None
0.36A 6ebzD-1r2fA:
42.5
6ebzD-1r2fA:
30.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1r2f PROTEIN
(RIBONUCLEOTIDE
REDUCTASE R2)


(Salmonella
enterica)
PF00268
(Ribonuc_red_sm)
9 PHE A  60
LEU A  63
THR A  64
ASP A  67
SER A 104
ILE A 108
PHE A 109
ILE A 185
ILE A 188
None
None
None
FE  A 400 (-3.0A)
None
None
None
None
None
0.53A 6ebzD-1r2fA:
42.5
6ebzD-1r2fA:
30.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1suh EPITHELIAL CADHERIN

(Mus musculus)
PF00028
(Cadherin)
5 LEU A  21
GLY A  58
ILE A  53
ILE A  96
ILE A   7
None
0.99A 6ebzD-1suhA:
undetectable
6ebzD-1suhA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdk L-AMINO ACID OXIDASE

(Gloydius halys)
PF01593
(Amino_oxidase)
5 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
None
0.92A 6ebzD-1tdkA:
undetectable
6ebzD-1tdkA:
10.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1uzr RIBONUCLEOTIDE
REDUCTASE R2-2 SMALL
SUBUNIT


(Mycobacterium
tuberculosis)
PF00268
(Ribonuc_red_sm)
9 PHE A  65
LEU A  68
THR A  69
ASP A  72
SER A 109
ILE A 113
PHE A 114
ILE A 190
ILE A 193
None
None
None
FE  A1292 (-2.5A)
None
None
None
None
None
0.46A 6ebzD-1uzrA:
41.0
6ebzD-1uzrA:
42.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1uzr RIBONUCLEOTIDE
REDUCTASE R2-2 SMALL
SUBUNIT


(Mycobacterium
tuberculosis)
PF00268
(Ribonuc_red_sm)
9 PHE A  65
LEU A  68
THR A  69
ASP A  72
SER A 109
ILE A 113
PHE A 171
ILE A 190
ILE A 193
None
None
None
FE  A1292 (-2.5A)
None
None
None
None
None
0.51A 6ebzD-1uzrA:
41.0
6ebzD-1uzrA:
42.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v33 DNA PRIMASE SMALL
SUBUNIT


(Pyrococcus
horikoshii)
PF01896
(DNA_primase_S)
5 SER A  73
GLY A  38
PHE A  39
ILE A  24
ILE A  28
None
1.00A 6ebzD-1v33A:
undetectable
6ebzD-1v33A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vlm SAM-DEPENDENT
METHYLTRANSFERASE


(Thermotoga
maritima)
PF08241
(Methyltransf_11)
5 LEU A 162
GLY A 204
ILE A 202
PHE A 171
ILE A 100
None
0.85A 6ebzD-1vlmA:
undetectable
6ebzD-1vlmA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vme FLAVOPROTEIN

(Thermotoga
maritima)
PF00258
(Flavodoxin_1)
5 PHE A 165
GLY A 227
PHE A  10
ILE A  15
ILE A   9
None
1.07A 6ebzD-1vmeA:
undetectable
6ebzD-1vmeA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xzw PURPLE ACID
PHOSPHATASE


(Ipomoea batatas)
PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N)
6 PHE A 129
LEU A 131
ILE A 393
PHE A 319
ILE A 281
ILE A 317
None
1.41A 6ebzD-1xzwA:
undetectable
6ebzD-1xzwA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yf2 TYPE I
RESTRICTION-MODIFICA
TION ENZYME, S
SUBUNIT


(Methanocaldococcus
jannaschii)
PF01420
(Methylase_S)
5 LEU A 417
THR A 418
GLY A  14
ILE A  13
PHE A 129
None
1.02A 6ebzD-1yf2A:
undetectable
6ebzD-1yf2A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a6o ISHP608 TRANSPOSASE

(Helicobacter
pylori)
PF01797
(Y1_Tnp)
6 PHE A  80
GLY A  76
ILE A  71
PHE A  75
ILE A  21
ILE A 113
None
1.20A 6ebzD-2a6oA:
undetectable
6ebzD-2a6oA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bm3 SCAFFOLDING DOCKERIN
BINDING PROTEIN A


(Ruminiclostridium
thermocellum)
PF00963
(Cohesin)
5 LEU A  73
GLY A  69
ILE A 116
PHE A  36
ILE A  30
None
0.94A 6ebzD-2bm3A:
undetectable
6ebzD-2bm3A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g0t CONSERVED
HYPOTHETICAL PROTEIN


(Thermotoga
maritima)
PF07755
(DUF1611)
PF17396
(DUF1611_N)
5 LEU A  38
GLY A 198
ILE A 199
ILE A 111
ILE A  82
None
1.01A 6ebzD-2g0tA:
undetectable
6ebzD-2g0tA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gb4 THIOPURINE
S-METHYLTRANSFERASE


(Mus musculus)
PF05724
(TPMT)
5 PHE A  61
GLY A 139
ILE A 138
ILE A 130
ILE A 164
None
None
None
SAH  A 300 (-4.5A)
None
1.06A 6ebzD-2gb4A:
undetectable
6ebzD-2gb4A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gep SULFITE REDUCTASE
HEMOPROTEIN


(Escherichia
coli)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr)
5 GLY A  89
ILE A 392
PHE A 122
ILE A 112
ILE A  99
None
1.04A 6ebzD-2gepA:
undetectable
6ebzD-2gepA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gwm 65 KDA VIRULENCE
PROTEIN


(Salmonella
enterica)
PF03496
(ADPrib_exo_Tox)
5 LEU A 427
THR A 426
GLY A 405
ILE A 409
PHE A 443
None
0.97A 6ebzD-2gwmA:
undetectable
6ebzD-2gwmA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnh DNA POLYMERASE III
ALPHA SUBUNIT


(Escherichia
coli)
PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6)
5 LEU A 879
GLY A 840
ILE A 838
ILE A 816
ILE A 849
None
1.08A 6ebzD-2hnhA:
undetectable
6ebzD-2hnhA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i5g AMIDOHYDROLASE

(Pseudomonas
aeruginosa)
PF01244
(Peptidase_M19)
5 PHE A 260
LEU A 263
THR A 264
GLY A 277
ILE A 279
None
1.07A 6ebzD-2i5gA:
undetectable
6ebzD-2i5gA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jdx PROTEIN
(L-ARGININE:GLYCINE
AMIDINOTRANSFERASE)


(Homo sapiens)
no annotation 5 PHE A 383
GLY A 387
ILE A 388
ILE A 311
ILE A 315
None
1.05A 6ebzD-2jdxA:
undetectable
6ebzD-2jdxA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mjp PYROPHOSPHATASE

(Methanocaldococcus
jannaschii)
PF01725
(Ham1p_like)
5 LEU A  28
ILE A  21
PHE A 185
ILE A  70
ILE A  11
None
0.90A 6ebzD-2mjpA:
undetectable
6ebzD-2mjpA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfe CALPAIN-7

(Homo sapiens)
PF01067
(Calpain_III)
5 LEU A 731
ILE A 692
PHE A 741
ILE A 784
ILE A 729
None
BR  A   8 ( 4.6A)
None
None
None
1.09A 6ebzD-2qfeA:
undetectable
6ebzD-2qfeA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rcc RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA


(Bacillus
halodurans)
PF00268
(Ribonuc_red_sm)
5 LEU A  84
SER A 124
PHE A 193
ILE A 212
ILE A 215
None
0.75A 6ebzD-2rccA:
27.6
6ebzD-2rccA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v73 PUTATIVE
EXO-ALPHA-SIALIDASE


(Clostridium
perfringens)
PF02973
(Sialidase)
5 LEU A  57
GLY A 147
ILE A 146
ILE A 169
ILE A  40
None
1.06A 6ebzD-2v73A:
undetectable
6ebzD-2v73A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdw VACCINIA VIRUS
CAPPING ENZYME D1
SUBUNIT


(Vaccinia virus)
PF03291
(Pox_MCEL)
5 THR A 701
PHE A 780
PHE A 659
ILE A 654
ILE A 597
None
0.99A 6ebzD-2vdwA:
undetectable
6ebzD-2vdwA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zzw ABC TRANSPORTER,
SOLUTE-BINDING
PROTEIN


(Thermus
thermophilus)
PF03480
(DctP)
5 PHE A 188
THR A 195
GLY A 181
ILE A 184
ILE A 160
None
0.92A 6ebzD-2zzwA:
undetectable
6ebzD-2zzwA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahx BETA-GLUCOSIDASE A

(Clostridium
cellulovorans)
PF00232
(Glyco_hydro_1)
5 PHE A 151
GLY A 215
ILE A 217
ILE A 119
ILE A 117
None
1.08A 6ebzD-3ahxA:
undetectable
6ebzD-3ahxA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c0r UBIQUITIN
THIOESTERASE OTU1


(Saccharomyces
cerevisiae)
PF02338
(OTU)
5 LEU A 138
GLY A 182
ILE A 192
PHE A 130
ILE A 129
None
0.91A 6ebzD-3c0rA:
undetectable
6ebzD-3c0rA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e5d PUTATIVE GLYOXALASE
I


(Listeria
monocytogenes)
PF00903
(Glyoxalase)
5 LEU A  87
THR A  88
PHE A  24
ILE A  76
ILE A 122
None
1.03A 6ebzD-3e5dA:
undetectable
6ebzD-3e5dA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e74 ALLANTOINASE

(Escherichia
coli)
PF01979
(Amidohydro_1)
5 PHE A 388
GLY A  10
ILE A   7
ILE A  30
ILE A  33
None
1.06A 6ebzD-3e74A:
undetectable
6ebzD-3e74A:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e9k KYNURENINASE

(Homo sapiens)
PF00266
(Aminotran_5)
5 LEU A 368
THR A 365
GLY A 400
ILE A 405
ILE A 390
None
0.97A 6ebzD-3e9kA:
undetectable
6ebzD-3e9kA:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgx RBSTP2171

(Geobacillus
stearothermophilus)
no annotation 5 LEU A  91
THR A  92
ILE A  73
PHE A  70
ILE A  23
None
0.93A 6ebzD-3fgxA:
undetectable
6ebzD-3fgxA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA


(Moorella
thermoacetica)
PF03063
(Prismane)
5 PHE A 174
LEU A 171
GLY A 207
ILE A 208
ILE A 247
None
0.98A 6ebzD-3i04A:
undetectable
6ebzD-3i04A:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j2s COAGULATION FACTOR
VIII LIGHT CHAIN


(Homo sapiens)
PF00754
(F5_F8_type_C)
PF07731
(Cu-oxidase_2)
5 PHE B2014
LEU B1932
GLY B1994
PHE B1876
ILE B1940
None
1.08A 6ebzD-3j2sB:
undetectable
6ebzD-3j2sB:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jcu OXYGEN-EVOLVING
ENHANCER PROTEIN 1,
CHLOROPLASTIC


(Spinacia
oleracea)
PF01716
(MSP)
6 PHE O 301
LEU O 285
THR O 284
ILE O 321
PHE O 134
ILE O 213
None
1.43A 6ebzD-3jcuO:
undetectable
6ebzD-3jcuO:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kg7 CURH

(Lyngbya
majuscula)
PF14765
(PS-DH)
5 LEU A1166
THR A1165
ILE A1195
ILE A1135
ILE A 985
None
1.01A 6ebzD-3kg7A:
undetectable
6ebzD-3kg7A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kzp PUTATIVE DIGUANYLATE
CYCLASE/PHOSPHODIEST
ERASE


(Listeria
monocytogenes)
PF00563
(EAL)
5 LEU A  96
ILE A 137
PHE A  63
ILE A  77
ILE A 103
None
1.02A 6ebzD-3kzpA:
undetectable
6ebzD-3kzpA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lk6 LIPOPROTEIN YBBD

(Bacillus
subtilis)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
5 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 455
None
1.07A 6ebzD-3lk6A:
undetectable
6ebzD-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lk6 LIPOPROTEIN YBBD

(Bacillus
subtilis)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
5 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 457
None
0.87A 6ebzD-3lk6A:
undetectable
6ebzD-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
8 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 176
ILE A 195
ILE A 198
None
None
None
MN3  A1001 (-2.2A)
None
None
None
None
0.68A 6ebzD-3mjoA:
41.0
6ebzD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
7 PHE A  70
LEU A  73
THR A  74
ILE A 118
PHE A 119
ILE A 195
ILE A 198
None
0.37A 6ebzD-3mjoA:
41.0
6ebzD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
7 PHE A  70
LEU A  73
THR A  74
SER A 114
ILE A 118
ILE A 195
ILE A 198
None
0.56A 6ebzD-3mjoA:
41.0
6ebzD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n00 REV-ERBA-ALPHA

(Homo sapiens)
PF00104
(Hormone_recep)
5 LEU A 545
THR A 541
ILE A 299
PHE A 300
ILE A 457
None
1.05A 6ebzD-3n00A:
undetectable
6ebzD-3n00A:
15.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA


(Escherichia
coli)
no annotation 7 PHE B  60
LEU B  63
ASP B  67
SER B 104
ILE B 108
ILE B 185
ILE B 188
None
None
MN  B 320 (-2.8A)
None
None
None
None
0.67A 6ebzD-3n3bB:
41.6
6ebzD-3n3bB:
30.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA


(Escherichia
coli)
no annotation 9 PHE B  60
LEU B  63
THR B  64
ASP B  67
ILE B 108
PHE B 109
PHE B 166
ILE B 185
ILE B 188
None
None
None
MN  B 320 (-2.8A)
None
None
None
None
None
0.48A 6ebzD-3n3bB:
41.6
6ebzD-3n3bB:
30.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3njx RHAMNOGALACTURONASE
B


(Aspergillus
aculeatus)
PF09284
(RhgB_N)
PF14683
(CBM-like)
PF14686
(fn3_3)
5 LEU A 506
GLY A 420
ILE A 419
ILE A 481
ILE A 403
None
1.00A 6ebzD-3njxA:
undetectable
6ebzD-3njxA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ojl CAP5O

(Staphylococcus
aureus)
PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N)
5 LEU A 221
THR A 222
GLY A 251
ILE A 247
ILE A 236
None
0.96A 6ebzD-3ojlA:
undetectable
6ebzD-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg1 CD180 MOLECULE

(Bos taurus)
PF00560
(LRR_1)
PF13855
(LRR_8)
5 LEU A 227
GLY A 208
PHE A 219
ILE A 214
ILE A 188
None
1.08A 6ebzD-3rg1A:
undetectable
6ebzD-3rg1A:
8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sun DNA POLYMERASE

(Escherichia
virus RB69)
PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1)
5 PHE A 841
GLY A 807
ILE A 846
ILE A 858
ILE A 815
None
1.07A 6ebzD-3sunA:
undetectable
6ebzD-3sunA:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w1s AUTOPHAGY PROTEIN 5

(Saccharomyces
cerevisiae)
PF04106
(APG5)
5 LEU A 263
THR A 228
ILE A 257
ILE A 279
ILE A 236
None
1.08A 6ebzD-3w1sA:
undetectable
6ebzD-3w1sA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wuy NITRILASE

(Synechocystis
sp. PCC 6803)
PF00795
(CN_hydrolase)
5 LEU A 106
GLY A 127
PHE A  51
ILE A  49
ILE A  38
None
1.05A 6ebzD-3wuyA:
undetectable
6ebzD-3wuyA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvo CRISPR-ASSOCIATED
PROTEIN, CSE1 FAMILY


(Thermobifida
fusca)
PF09481
(CRISPR_Cse1)
6 LEU A 213
GLY A  68
ILE A  66
PHE A  34
ILE A  93
ILE A  61
None
1.41A 6ebzD-3wvoA:
undetectable
6ebzD-3wvoA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmr RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA


(Bacillus cereus)
PF00268
(Ribonuc_red_sm)
8 LEU A  58
THR A  59
ASP A  62
ILE A 103
PHE A 104
PHE A 169
ILE A 188
ILE A 191
None
None
FE2  A1323 (-2.4A)
None
None
None
None
None
0.55A 6ebzD-4bmrA:
38.5
6ebzD-4bmrA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmr RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA


(Bacillus cereus)
PF00268
(Ribonuc_red_sm)
7 LEU A  58
THR A  59
ASP A  62
SER A  99
ILE A 103
ILE A 188
ILE A 191
None
None
FE2  A1323 (-2.4A)
None
None
None
None
0.69A 6ebzD-4bmrA:
38.5
6ebzD-4bmrA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ckb MRNA-CAPPING ENZYME
CATALYTIC SUBUNIT


(Vaccinia virus)
PF03291
(Pox_MCEL)
PF10640
(Pox_ATPase-GT)
6 LEU A 700
THR A 701
PHE A 780
PHE A 659
ILE A 654
ILE A 597
None
1.14A 6ebzD-4ckbA:
undetectable
6ebzD-4ckbA:
6.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cp6 CHOLINE BINDING
PROTEIN PCPA


(Streptococcus
pneumoniae)
PF13306
(LRR_5)
5 LEU A 345
GLY A 371
ILE A 374
PHE A 336
ILE A 331
None
1.04A 6ebzD-4cp6A:
undetectable
6ebzD-4cp6A:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dr0 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA


(Bacillus
subtilis)
PF00268
(Ribonuc_red_sm)
9 LEU A  62
THR A  63
ASP A  66
SER A 104
ILE A 108
PHE A 109
PHE A 172
ILE A 191
ILE A 194
None
None
MN  A 402 (-2.3A)
None
None
None
None
None
None
0.57A 6ebzD-4dr0A:
38.7
6ebzD-4dr0A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fd0 LEUCINE RICH
HYPOTHETICAL PROTEIN


(Bacteroides
caccae)
PF07523
(Big_3)
PF13306
(LRR_5)
5 PHE A 294
LEU A 323
ILE A 267
PHE A 332
ILE A 318
None
1.09A 6ebzD-4fd0A:
undetectable
6ebzD-4fd0A:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fin ETTA (YJJK) ABCF
FAMILY PROTEIN


(Escherichia
coli)
PF00005
(ABC_tran)
PF12848
(ABC_tran_Xtn)
5 LEU A 365
THR A 364
GLY A 359
ILE A 354
ILE A 497
None
None
SO4  A 603 (-3.3A)
None
None
1.09A 6ebzD-4finA:
undetectable
6ebzD-4finA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fs7 UNCHARACTERIZED
PROTEIN


(Bacteroides
ovatus)
PF13306
(LRR_5)
5 PHE A  87
GLY A 106
ILE A  82
ILE A  96
ILE A 119
None
0.92A 6ebzD-4fs7A:
undetectable
6ebzD-4fs7A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fs7 UNCHARACTERIZED
PROTEIN


(Bacteroides
ovatus)
PF13306
(LRR_5)
5 PHE A 133
GLY A 152
ILE A 128
ILE A 142
ILE A 164
None
0.95A 6ebzD-4fs7A:
undetectable
6ebzD-4fs7A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fs7 UNCHARACTERIZED
PROTEIN


(Bacteroides
ovatus)
PF13306
(LRR_5)
5 PHE A 336
GLY A 355
ILE A 331
ILE A 345
ILE A 368
None
0.76A 6ebzD-4fs7A:
undetectable
6ebzD-4fs7A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g38 SULFITE REDUCTASE
[NADPH] HEMOPROTEIN
BETA-COMPONENT


(Escherichia
coli)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr)
5 GLY A  89
ILE A 392
PHE A 122
ILE A 112
ILE A  99
None
1.01A 6ebzD-4g38A:
undetectable
6ebzD-4g38A:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g4s PROTEASOME CHAPERONE
1


(Saccharomyces
cerevisiae)
PF10450
(POC1)
5 PHE O  38
GLY O  72
ILE O 124
ILE O 154
ILE O 150
None
1.08A 6ebzD-4g4sO:
undetectable
6ebzD-4g4sO:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN


(Bacteroides
fragilis)
PF00092
(VWA)
5 ASP A 129
GLY A 132
ILE A  94
ILE A 283
ILE A 287
None
0.77A 6ebzD-4jduA:
undetectable
6ebzD-4jduA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3y NEURAMINIDASE

(Influenza A
virus)
PF00064
(Neur)
5 PHE A 374
LEU A 397
ILE A 404
PHE A 446
ILE A 444
None
1.06A 6ebzD-4k3yA:
undetectable
6ebzD-4k3yA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n83 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA


(Streptococcus
sanguinis)
PF00268
(Ribonuc_red_sm)
10 PHE A  59
LEU A  62
THR A  63
ASP A  66
SER A 103
ILE A 107
PHE A 108
PHE A 165
ILE A 184
ILE A 187
None
None
None
MN  A 402 (-2.8A)
None
None
None
None
None
None
0.52A 6ebzD-4n83A:
38.7
6ebzD-4n83A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p5w CALCIUM-BINDING
MITOCHONDRIAL
CARRIER PROTEIN
ARALAR2,CALCIUM-BIND
ING MITOCHONDRIAL
CARRIER PROTEIN
ARALAR2


(Homo sapiens)
no annotation 5 THR A 265
GLY A 222
ILE A 271
PHE A 254
ILE A 233
None
0.92A 6ebzD-4p5wA:
undetectable
6ebzD-4p5wA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qku HYDROLASE

(Burkholderia
cenocepacia)
PF01557
(FAA_hydrolase)
PF09298
(FAA_hydrolase_N)
5 LEU A 245
GLY A 364
ILE A 366
PHE A 420
ILE A 312
None
0.98A 6ebzD-4qkuA:
undetectable
6ebzD-4qkuA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xru HEN1

(Capnocytophaga
gingivalis)
no annotation 5 PHE C  84
LEU C  87
ILE C  79
ILE C   5
ILE C 116
None
1.00A 6ebzD-4xruC:
undetectable
6ebzD-4xruC:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aex AMMONIUM TRANSPORTER
MEP2


(Saccharomyces
cerevisiae)
PF00909
(Ammonium_transp)
5 LEU A  56
GLY A 142
ILE A  49
ILE A 297
ILE A 347
None
1.04A 6ebzD-5aexA:
2.6
6ebzD-5aexA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5djw ALPHA-GLUCOSIDASE II

(Bacteroides
thetaiotaomicron)
PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF17137
(DUF5110)
5 LEU A 164
THR A 165
GLY A 423
ILE A 158
ILE A 149
None
1.08A 6ebzD-5djwA:
undetectable
6ebzD-5djwA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hiu GTPASE
ACTIVATOR-LIKE
PROTEIN


(Chaetomium
thermophilum)
PF11864
(DUF3384)
6 PHE A 207
LEU A 210
THR A 211
GLY A 276
ILE A 274
ILE A 262
PHE  A 207 ( 1.3A)
LEU  A 210 ( 0.5A)
THR  A 211 ( 0.8A)
GLY  A 276 ( 0.0A)
ILE  A 274 ( 0.7A)
ILE  A 262 ( 0.7A)
0.99A 6ebzD-5hiuA:
undetectable
6ebzD-5hiuA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iw9 BASEPLATE WEDGE
PROTEIN GP25


(Escherichia
virus T4)
PF04965
(GPW_gp25)
5 GLY A  38
ILE A  39
PHE A 110
ILE A  88
ILE A  32
None
0.96A 6ebzD-5iw9A:
undetectable
6ebzD-5iw9A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m0y CELLULOSOME
ANCHORING PROTEIN
COHESIN REGION


(Ruminiclostridium
thermocellum)
PF00963
(Cohesin)
5 LEU A  85
GLY A  81
ILE A 128
PHE A  48
ILE A  42
None
P6G  A 205 (-3.6A)
P6G  A 205 (-4.9A)
None
None
0.92A 6ebzD-5m0yA:
undetectable
6ebzD-5m0yA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mso CARBOXYLIC ACID
REDUCTASE


(Mycobacterium
marinum)
PF07993
(NAD_binding_4)
5 LEU A1071
ILE A1085
PHE A1002
ILE A1006
ILE A1161
None
0.89A 6ebzD-5msoA:
undetectable
6ebzD-5msoA:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd1 CAPSID PROTEIN

(Rosellinia
necatrix
quadrivirus 1)
no annotation 5 ASP A 254
SER A 628
GLY A 727
ILE A 731
ILE A 626
None
1.04A 6ebzD-5nd1A:
undetectable
6ebzD-5nd1A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szs SPIKE GLYCOPROTEIN

(Human
coronavirus
NL63)
PF01600
(Corona_S1)
PF01601
(Corona_S2)
5 LEU A 151
THR A 159
ILE A 144
ILE A  89
ILE A 105
None
0.95A 6ebzD-5szsA:
undetectable
6ebzD-5szsA:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ti1 FUMARYLACETOACETATE
HYDROLASE


(Paraburkholderia
xenovorans)
PF01557
(FAA_hydrolase)
PF09298
(FAA_hydrolase_N)
5 LEU A 249
GLY A 368
ILE A 370
PHE A 424
ILE A 316
None
MG  A 501 ( 4.7A)
None
None
None
0.96A 6ebzD-5ti1A:
undetectable
6ebzD-5ti1A:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ucd NAD(P)-DEPENDENT
BENZALDEHYDE
DEHYDROGENASE


(Pseudomonas
putida)
PF00171
(Aldedh)
6 LEU A 127
THR A 128
GLY A 132
ILE A 134
ILE A 159
ILE A 142
None
1.16A 6ebzD-5ucdA:
undetectable
6ebzD-5ucdA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT


(Alcaligenes
faecalis)
PF06355
(Aegerolysin)
5 PHE A  97
LEU A 113
ASP A 111
GLY A  86
ILE A 138
None
1.02A 6ebzD-5v3sA:
undetectable
6ebzD-5v3sA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z2g L-AMINO ACID OXIDASE

(Naja atra)
no annotation 5 PHE A 398
LEU A 401
ASP A 402
ILE A 344
ILE A 409
None
0.95A 6ebzD-5z2gA:
undetectable
6ebzD-5z2gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ged PRGB

(Enterococcus
faecalis)
no annotation 5 PHE A 275
THR A 549
ILE A 369
ILE A 418
ILE A 523
None
1.04A 6ebzD-6gedA:
undetectable
6ebzD-6gedA:
20.24