SIMILAR PATTERNS OF AMINO ACIDS FOR 6EBZ_C_DAHC123
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a7j | PHOSPHORIBULOKINASE (Rhodobactersphaeroides) |
PF00485(PRK) | 5 | PHE A 84GLY A 88ILE A 7PHE A 44ILE A 39 | None | 0.84A | 6ebzC-1a7jA:undetectable | 6ebzC-1a7jA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ize | ASPARTIC PROTEINASE (Aspergillusoryzae) |
PF00026(Asp) | 5 | THR A 267GLY A 201ILE A 200ILE A 287ILE A 273 | None | 0.90A | 6ebzC-1izeA:undetectable | 6ebzC-1izeA:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kgp | RIBONUCLEOTIDEREDUCTASE PROTEINR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 10 | PHE A 70LEU A 73THR A 74ASP A 77SER A 114ILE A 118PHE A 119PHE A 176ILE A 195ILE A 198 | NoneNoneNone MN A1001 (-2.7A)NoneNoneNoneNoneNoneNone | 0.44A | 6ebzC-1kgpA:42.5 | 6ebzC-1kgpA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ocx | MALTOSEO-ACETYLTRANSFERASE (Escherichiacoli) |
PF12464(Mac)PF14602(Hexapep_2) | 5 | THR A 149GLY A 133ILE A 96ILE A 108ILE A 144 | None | 1.06A | 6ebzC-1ocxA:undetectable | 6ebzC-1ocxA:17.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oh9 | ACETYLGLUTAMATEKINASE (Escherichiacoli) |
PF00696(AA_kinase) | 5 | PHE A 24LEU A 23ILE A 97ILE A 40ILE A 7 | None | 1.04A | 6ebzC-1oh9A:undetectable | 6ebzC-1oh9A:11.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pc3 | PHOSPHATE-BINDINGPROTEIN 1 (Mycobacteriumtuberculosis) |
PF12849(PBP_like_2) | 6 | PHE A 312LEU A 309THR A 308ILE A 58PHE A 49ILE A 79 | None | 1.45A | 6ebzC-1pc3A:undetectable | 6ebzC-1pc3A:11.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pg5 | ASPARTATECARBAMOYLTRANSFERASE (Sulfolobusacidocaldarius) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | LEU A 1GLY A 298PHE A 10ILE A 18ILE A 292 | None | 1.04A | 6ebzC-1pg5A:undetectable | 6ebzC-1pg5A:15.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pm2 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1BETA CHAIN (Escherichiacoli) |
PF00268(Ribonuc_red_sm) | 5 | SER A 121ILE A 125PHE A 212ILE A 231ILE A 234 | None | 0.95A | 6ebzC-1pm2A:28.9 | 6ebzC-1pm2A:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pm2 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1BETA CHAIN (Escherichiacoli) |
PF00268(Ribonuc_red_sm) | 5 | THR A 81SER A 121ILE A 125ILE A 231ILE A 234 | None | 0.81A | 6ebzC-1pm2A:28.9 | 6ebzC-1pm2A:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qqj | FUMARYLACETOACETATEHYDROLASE (Mus musculus) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 5 | LEU A 230GLY A 349ILE A 351PHE A 405ILE A 297 | None CA A 420 ( 4.5A)NoneNoneNone | 1.04A | 6ebzC-1qqjA:undetectable | 6ebzC-1qqjA:9.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1r2f | PROTEIN(RIBONUCLEOTIDEREDUCTASE R2) (Salmonellaenterica) |
PF00268(Ribonuc_red_sm) | 10 | PHE A 60LEU A 63THR A 64ASP A 67SER A 104ILE A 108PHE A 109PHE A 166ILE A 185ILE A 188 | NoneNoneNone FE A 400 (-3.0A)NoneNoneNoneNoneNoneNone | 0.35A | 6ebzC-1r2fA:43.0 | 6ebzC-1r2fA:30.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1suh | EPITHELIAL CADHERIN (Mus musculus) |
PF00028(Cadherin) | 5 | LEU A 21GLY A 58ILE A 53ILE A 96ILE A 7 | None | 1.00A | 6ebzC-1suhA:undetectable | 6ebzC-1suhA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdk | L-AMINO ACID OXIDASE (Gloydius halys) |
PF01593(Amino_oxidase) | 5 | PHE A 381LEU A 384ASP A 385ILE A 327ILE A 392 | None | 0.97A | 6ebzC-1tdkA:undetectable | 6ebzC-1tdkA:10.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 6 | PHE A 65LEU A 68THR A 66ILE A 113PHE A 114ILE A 190 | None | 1.49A | 6ebzC-1uzrA:41.4 | 6ebzC-1uzrA:42.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 9 | PHE A 65LEU A 68THR A 69ASP A 72ILE A 113PHE A 114PHE A 171ILE A 190ILE A 193 | NoneNoneNone FE A1292 (-2.5A)NoneNoneNoneNoneNone | 0.54A | 6ebzC-1uzrA:41.4 | 6ebzC-1uzrA:42.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 7 | THR A 69ASP A 72SER A 109ILE A 113PHE A 114PHE A 171ILE A 193 | None FE A1292 (-2.5A)NoneNoneNoneNoneNone | 0.85A | 6ebzC-1uzrA:41.4 | 6ebzC-1uzrA:42.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vlm | SAM-DEPENDENTMETHYLTRANSFERASE (Thermotogamaritima) |
PF08241(Methyltransf_11) | 5 | LEU A 162GLY A 204ILE A 202PHE A 171ILE A 100 | None | 0.87A | 6ebzC-1vlmA:undetectable | 6ebzC-1vlmA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vme | FLAVOPROTEIN (Thermotogamaritima) |
PF00258(Flavodoxin_1) | 5 | PHE A 165GLY A 227PHE A 10ILE A 15ILE A 9 | None | 1.06A | 6ebzC-1vmeA:undetectable | 6ebzC-1vmeA:12.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xzw | PURPLE ACIDPHOSPHATASE (Ipomoea batatas) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 6 | PHE A 129LEU A 131ILE A 393PHE A 319ILE A 281ILE A 317 | None | 1.42A | 6ebzC-1xzwA:undetectable | 6ebzC-1xzwA:12.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yf2 | TYPE IRESTRICTION-MODIFICATION ENZYME, SSUBUNIT (Methanocaldococcusjannaschii) |
PF01420(Methylase_S) | 5 | LEU A 417THR A 418GLY A 14ILE A 13PHE A 129 | None | 1.03A | 6ebzC-1yf2A:undetectable | 6ebzC-1yf2A:10.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a6o | ISHP608 TRANSPOSASE (Helicobacterpylori) |
PF01797(Y1_Tnp) | 6 | PHE A 80GLY A 76ILE A 71PHE A 75ILE A 21ILE A 113 | None | 1.20A | 6ebzC-2a6oA:undetectable | 6ebzC-2a6oA:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aaa | ALPHA-AMYLASE (Aspergillusniger) |
PF00128(Alpha-amylase)PF09260(DUF1966) | 5 | PHE A 262LEU A 258SER A 268GLY A 267ILE A 394 | None | 1.07A | 6ebzC-2aaaA:undetectable | 6ebzC-2aaaA:9.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bdr | UREIDOGLYCOLATEHYDROLASE (Pseudomonasputida) |
PF04115(Ureidogly_lyase) | 5 | PHE A 14THR A 10SER A 112ILE A 93PHE A 110 | None | 1.00A | 6ebzC-2bdrA:undetectable | 6ebzC-2bdrA:16.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bm3 | SCAFFOLDING DOCKERINBINDING PROTEIN A (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 5 | LEU A 73GLY A 69ILE A 116PHE A 36ILE A 30 | None | 0.98A | 6ebzC-2bm3A:undetectable | 6ebzC-2bm3A:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g0t | CONSERVEDHYPOTHETICAL PROTEIN (Thermotogamaritima) |
PF07755(DUF1611)PF17396(DUF1611_N) | 5 | LEU A 38GLY A 198ILE A 199ILE A 111ILE A 82 | None | 1.00A | 6ebzC-2g0tA:undetectable | 6ebzC-2g0tA:13.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g28 | PYRUVATEDEHYDROGENASE E1COMPONENT (Escherichiacoli) |
PF00456(Transketolase_N) | 5 | PHE A 532LEU A 531GLY A 562ILE A 537ILE A 519 | None | 1.02A | 6ebzC-2g28A:undetectable | 6ebzC-2g28A:7.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gep | SULFITE REDUCTASEHEMOPROTEIN (Escherichiacoli) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | GLY A 89ILE A 392PHE A 122ILE A 112ILE A 99 | None | 1.05A | 6ebzC-2gepA:undetectable | 6ebzC-2gepA:9.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gwm | 65 KDA VIRULENCEPROTEIN (Salmonellaenterica) |
PF03496(ADPrib_exo_Tox) | 5 | LEU A 427THR A 426GLY A 405ILE A 409PHE A 443 | None | 1.05A | 6ebzC-2gwmA:undetectable | 6ebzC-2gwmA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i5g | AMIDOHYDROLASE (Pseudomonasaeruginosa) |
PF01244(Peptidase_M19) | 5 | PHE A 260LEU A 263THR A 264GLY A 277ILE A 279 | None | 1.01A | 6ebzC-2i5gA:undetectable | 6ebzC-2i5gA:12.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ifa | HYPOTHETICAL PROTEINSMU.260 (Streptococcusmutans) |
PF00881(Nitroreductase) | 5 | PHE A 176GLY A 144ILE A 143ILE A 32ILE A 134 | None | 1.00A | 6ebzC-2ifaA:undetectable | 6ebzC-2ifaA:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iu4 | DIHYDROXYACETONEKINASE (Lactococcuslactis) |
PF02733(Dak1) | 5 | LEU A 185THR A 184ASP A 133ILE A 303ILE A 212 | None | 1.02A | 6ebzC-2iu4A:undetectable | 6ebzC-2iu4A:13.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mjp | PYROPHOSPHATASE (Methanocaldococcusjannaschii) |
PF01725(Ham1p_like) | 5 | LEU A 28ILE A 21PHE A 185ILE A 70ILE A 11 | None | 0.95A | 6ebzC-2mjpA:undetectable | 6ebzC-2mjpA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdw | VACCINIA VIRUSCAPPING ENZYME D1SUBUNIT (Vaccinia virus) |
PF03291(Pox_MCEL) | 5 | LEU A 700PHE A 780PHE A 659ILE A 654ILE A 597 | None | 0.95A | 6ebzC-2vdwA:undetectable | 6ebzC-2vdwA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yr1 | 3-DEHYDROQUINATEDEHYDRATASE (Geobacilluskaustophilus) |
PF01487(DHquinase_I) | 5 | THR A 205GLY A 223ILE A 3ILE A 15ILE A 172 | None | 1.07A | 6ebzC-2yr1A:undetectable | 6ebzC-2yr1A:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z00 | DIHYDROOROTASE (Thermusthermophilus) |
PF01979(Amidohydro_1) | 5 | LEU A 413THR A 414SER A 377GLY A 50ILE A 23 | None | 1.03A | 6ebzC-2z00A:undetectable | 6ebzC-2z00A:10.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzw | ABC TRANSPORTER,SOLUTE-BINDINGPROTEIN (Thermusthermophilus) |
PF03480(DctP) | 5 | PHE A 188THR A 195GLY A 181ILE A 184ILE A 160 | None | 0.94A | 6ebzC-2zzwA:undetectable | 6ebzC-2zzwA:10.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahx | BETA-GLUCOSIDASE A (Clostridiumcellulovorans) |
PF00232(Glyco_hydro_1) | 5 | PHE A 151GLY A 215ILE A 217ILE A 119ILE A 117 | None | 1.06A | 6ebzC-3ahxA:undetectable | 6ebzC-3ahxA:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c0r | UBIQUITINTHIOESTERASE OTU1 (Saccharomycescerevisiae) |
PF02338(OTU) | 5 | LEU A 138GLY A 182ILE A 192PHE A 130ILE A 129 | None | 0.92A | 6ebzC-3c0rA:undetectable | 6ebzC-3c0rA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cyg | UNCHARACTERIZEDPROTEIN (Fervidobacteriumnodosum) |
PF11738(DUF3298)PF13739(DUF4163) | 5 | PHE A 201GLY A 207ILE A 203PHE A 197ILE A 160 | None | 1.06A | 6ebzC-3cygA:undetectable | 6ebzC-3cygA:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d5f | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR DELTA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 296THR A 297SER A 302ILE A 303PHE A 306PHE A 226 | None | 1.43A | 6ebzC-3d5fA:3.5 | 6ebzC-3d5fA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e5d | PUTATIVE GLYOXALASEI (Listeriamonocytogenes) |
PF00903(Glyoxalase) | 5 | LEU A 87THR A 88PHE A 24ILE A 76ILE A 122 | None | 1.04A | 6ebzC-3e5dA:undetectable | 6ebzC-3e5dA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9k | KYNURENINASE (Homo sapiens) |
PF00266(Aminotran_5) | 5 | LEU A 368THR A 365GLY A 400ILE A 405ILE A 390 | None | 1.03A | 6ebzC-3e9kA:undetectable | 6ebzC-3e9kA:10.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eye | PTS SYSTEMN-ACETYLGALACTOSAMINE-SPECIFIC IIBCOMPONENT 1 (Escherichiacoli) |
PF03830(PTSIIB_sorb) | 5 | PHE A 83LEU A 33SER A 26GLY A 29ILE A 28 | None | 0.87A | 6ebzC-3eyeA:undetectable | 6ebzC-3eyeA:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgx | RBSTP2171 (Geobacillusstearothermophilus) |
no annotation | 5 | LEU A 91THR A 92ILE A 73PHE A 70ILE A 23 | None | 0.93A | 6ebzC-3fgxA:undetectable | 6ebzC-3fgxA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETA (Moorellathermoacetica) |
PF03063(Prismane) | 5 | PHE A 174LEU A 171GLY A 207ILE A 208ILE A 247 | None | 0.96A | 6ebzC-3i04A:undetectable | 6ebzC-3i04A:7.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j2s | COAGULATION FACTORVIII LIGHT CHAIN (Homo sapiens) |
PF00754(F5_F8_type_C)PF07731(Cu-oxidase_2) | 5 | PHE B2014LEU B1932GLY B1994PHE B1876ILE B1940 | None | 1.04A | 6ebzC-3j2sB:undetectable | 6ebzC-3j2sB:8.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jcu | OXYGEN-EVOLVINGENHANCER PROTEIN 1,CHLOROPLASTIC (Spinaciaoleracea) |
PF01716(MSP) | 6 | PHE O 301LEU O 285THR O 284ILE O 321PHE O 134ILE O 213 | None | 1.39A | 6ebzC-3jcuO:undetectable | 6ebzC-3jcuO:12.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kdn | RIBULOSEBISPHOSPHATECARBOXYLASE (Thermococcuskodakarensis) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 5 | SER A 107GLY A 110ILE A 112PHE A 113ILE A 89 | None | 0.98A | 6ebzC-3kdnA:undetectable | 6ebzC-3kdnA:11.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kg7 | CURH (Lyngbyamajuscula) |
PF14765(PS-DH) | 5 | LEU A1166THR A1165ILE A1195ILE A1135ILE A 985 | None | 0.99A | 6ebzC-3kg7A:undetectable | 6ebzC-3kg7A:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk6 | LIPOPROTEIN YBBD (Bacillussubtilis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 5 | PHE A 604THR A 471GLY A 599ILE A 603ILE A 457 | None | 0.87A | 6ebzC-3lk6A:undetectable | 6ebzC-3lk6A:8.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 7 | PHE A 70LEU A 73SER A 114ILE A 118PHE A 119PHE A 172ILE A 198 | NoneNoneNoneNoneNoneMN3 A1001 ( 4.5A)None | 1.42A | 6ebzC-3mjoA:41.4 | 6ebzC-3mjoA:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 9 | PHE A 70LEU A 73THR A 74ASP A 77SER A 114ILE A 118PHE A 176ILE A 195ILE A 198 | NoneNoneNoneMN3 A1001 (-2.2A)NoneNoneNoneNoneNone | 0.64A | 6ebzC-3mjoA:41.4 | 6ebzC-3mjoA:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 9 | PHE A 70LEU A 73THR A 74SER A 114ILE A 118PHE A 119PHE A 176ILE A 195ILE A 198 | None | 0.58A | 6ebzC-3mjoA:41.4 | 6ebzC-3mjoA:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n00 | REV-ERBA-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 545THR A 541ILE A 299PHE A 300ILE A 457 | None | 1.06A | 6ebzC-3n00A:undetectable | 6ebzC-3n00A:15.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n3b | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2SUBUNIT BETA (Escherichiacoli) |
no annotation | 10 | PHE B 60LEU B 63THR B 64ASP B 67SER B 104ILE B 108PHE B 109PHE B 166ILE B 185ILE B 188 | NoneNoneNone MN B 320 (-2.8A)NoneNoneNoneNoneNoneNone | 0.43A | 6ebzC-3n3bB:42.3 | 6ebzC-3n3bB:30.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3njx | RHAMNOGALACTURONASEB (Aspergillusaculeatus) |
PF09284(RhgB_N)PF14683(CBM-like)PF14686(fn3_3) | 5 | LEU A 506GLY A 420ILE A 419ILE A 481ILE A 403 | None | 1.04A | 6ebzC-3njxA:undetectable | 6ebzC-3njxA:9.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojl | CAP5O (Staphylococcusaureus) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | LEU A 221THR A 222GLY A 251ILE A 247ILE A 236 | None | 1.00A | 6ebzC-3ojlA:undetectable | 6ebzC-3ojlA:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojl | CAP5O (Staphylococcusaureus) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | LEU A 368THR A 308SER A 365ILE A 298ILE A 299 | None | 0.92A | 6ebzC-3ojlA:undetectable | 6ebzC-3ojlA:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ouu | BIOTIN CARBOXYLASE (Campylobacterjejuni) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | LEU A 62SER A 34GLY A 53ILE A 52PHE A 85 | None | 1.07A | 6ebzC-3ouuA:undetectable | 6ebzC-3ouuA:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wvo | CRISPR-ASSOCIATEDPROTEIN, CSE1 FAMILY (Thermobifidafusca) |
PF09481(CRISPR_Cse1) | 6 | LEU A 213GLY A 68ILE A 66PHE A 34ILE A 93ILE A 61 | None | 1.44A | 6ebzC-3wvoA:undetectable | 6ebzC-3wvoA:8.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2l | TWO-COMPONENT SYSTEMSENSOR HISTIDINEKINASE/RESPONSE (Bacteroidesthetaiotaomicron) |
PF07494(Reg_prop)PF07495(Y_Y_Y) | 5 | THR A 666SER A 765GLY A 767ILE A 338ILE A 719 | None | 0.98A | 6ebzC-4a2lA:undetectable | 6ebzC-4a2lA:7.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4az7 | BETA-N-ACETYLHEXOSAMINIDASE (Streptococcuspneumoniae) |
PF00728(Glyco_hydro_20) | 5 | THR A 217GLY A 511ILE A 510ILE A 354ILE A 289 | None | 1.05A | 6ebzC-4az7A:undetectable | 6ebzC-4az7A:9.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmr | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillus cereus) |
PF00268(Ribonuc_red_sm) | 9 | LEU A 58THR A 59ASP A 62SER A 99ILE A 103PHE A 104PHE A 169ILE A 188ILE A 191 | NoneNoneFE2 A1323 (-2.4A)NoneNoneNoneNoneNoneNone | 0.50A | 6ebzC-4bmrA:38.9 | 6ebzC-4bmrA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ckb | MRNA-CAPPING ENZYMECATALYTIC SUBUNIT (Vaccinia virus) |
PF03291(Pox_MCEL)PF10640(Pox_ATPase-GT) | 6 | LEU A 700THR A 701PHE A 780PHE A 659ILE A 654ILE A 597 | None | 1.18A | 6ebzC-4ckbA:undetectable | 6ebzC-4ckbA:6.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cp6 | CHOLINE BINDINGPROTEIN PCPA (Streptococcuspneumoniae) |
PF13306(LRR_5) | 5 | LEU A 345GLY A 371ILE A 374PHE A 336ILE A 331 | None | 0.98A | 6ebzC-4cp6A:undetectable | 6ebzC-4cp6A:12.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dr0 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillussubtilis) |
PF00268(Ribonuc_red_sm) | 8 | LEU A 62THR A 63ASP A 66ILE A 108PHE A 109PHE A 172ILE A 191ILE A 194 | NoneNone MN A 402 (-2.3A)NoneNoneNoneNoneNone | 0.58A | 6ebzC-4dr0A:39.0 | 6ebzC-4dr0A:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dr0 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillussubtilis) |
PF00268(Ribonuc_red_sm) | 7 | THR A 63ASP A 66SER A 104ILE A 108PHE A 109PHE A 172ILE A 194 | None MN A 402 (-2.3A)NoneNoneNoneNoneNone | 0.72A | 6ebzC-4dr0A:39.0 | 6ebzC-4dr0A:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 87GLY A 106ILE A 82ILE A 96ILE A 119 | None | 0.98A | 6ebzC-4fs7A:undetectable | 6ebzC-4fs7A:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 133GLY A 152ILE A 128ILE A 142ILE A 164 | None | 0.98A | 6ebzC-4fs7A:undetectable | 6ebzC-4fs7A:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 336GLY A 355ILE A 331ILE A 345ILE A 368 | None | 0.80A | 6ebzC-4fs7A:undetectable | 6ebzC-4fs7A:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g38 | SULFITE REDUCTASE[NADPH] HEMOPROTEINBETA-COMPONENT (Escherichiacoli) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | GLY A 89ILE A 392PHE A 122ILE A 112ILE A 99 | None | 1.01A | 6ebzC-4g38A:undetectable | 6ebzC-4g38A:8.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g4s | PROTEASOME CHAPERONE1 (Saccharomycescerevisiae) |
PF10450(POC1) | 5 | PHE O 38GLY O 72ILE O 124ILE O 154ILE O 150 | None | 1.05A | 6ebzC-4g4sO:undetectable | 6ebzC-4g4sO:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdu | AEROTOLERANCE-RELATED MEMBRANE PROTEIN (Bacteroidesfragilis) |
PF00092(VWA) | 5 | ASP A 129GLY A 132ILE A 94ILE A 283ILE A 287 | None | 0.80A | 6ebzC-4jduA:undetectable | 6ebzC-4jduA:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3y | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 6 | PHE A 374LEU A 397SER A 402ILE A 404PHE A 446ILE A 444 | None | 1.23A | 6ebzC-4k3yA:undetectable | 6ebzC-4k3yA:11.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m1e | PURINE NUCLEOSIDEPHOSPHORYLASE (Planctopiruslimnophila) |
PF01048(PNP_UDP_1) | 5 | PHE A 231LEU A 110ILE A 129ILE A 269ILE A 273 | None | 1.05A | 6ebzC-4m1eA:undetectable | 6ebzC-4m1eA:14.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n83 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Streptococcussanguinis) |
PF00268(Ribonuc_red_sm) | 9 | PHE A 59LEU A 62THR A 63ASP A 66ILE A 107PHE A 108PHE A 165ILE A 184ILE A 187 | NoneNoneNone MN A 402 (-2.8A)NoneNoneNoneNoneNone | 0.53A | 6ebzC-4n83A:39.1 | 6ebzC-4n83A:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n83 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Streptococcussanguinis) |
PF00268(Ribonuc_red_sm) | 7 | PHE A 59THR A 63SER A 103ILE A 107PHE A 108PHE A 165ILE A 187 | None | 0.69A | 6ebzC-4n83A:39.1 | 6ebzC-4n83A:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p5w | CALCIUM-BINDINGMITOCHONDRIALCARRIER PROTEINARALAR2,CALCIUM-BINDING MITOCHONDRIALCARRIER PROTEINARALAR2 (Homo sapiens) |
no annotation | 5 | THR A 265GLY A 222ILE A 271PHE A 254ILE A 233 | None | 0.95A | 6ebzC-4p5wA:undetectable | 6ebzC-4p5wA:11.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qku | HYDROLASE (Burkholderiacenocepacia) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 5 | LEU A 245GLY A 364ILE A 366PHE A 420ILE A 312 | None | 1.03A | 6ebzC-4qkuA:undetectable | 6ebzC-4qkuA:12.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xb1 | 319AA LONGHYPOTHETICALHOMOSERINEDEHYDROGENASE (Pyrococcushorikoshii) |
PF00742(Homoserine_dh)PF03447(NAD_binding_3) | 5 | LEU A 50SER A 36GLY A 46ILE A 44ILE A 7 | None | 1.05A | 6ebzC-4xb1A:undetectable | 6ebzC-4xb1A:16.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xru | HEN1 (Capnocytophagagingivalis) |
no annotation | 5 | PHE C 84LEU C 87ILE C 79ILE C 5ILE C 116 | None | 1.02A | 6ebzC-4xruC:undetectable | 6ebzC-4xruC:11.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aex | AMMONIUM TRANSPORTERMEP2 (Saccharomycescerevisiae) |
PF00909(Ammonium_transp) | 5 | LEU A 56GLY A 142ILE A 49ILE A 297ILE A 347 | None | 1.03A | 6ebzC-5aexA:2.6 | 6ebzC-5aexA:9.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5djw | ALPHA-GLUCOSIDASE II (Bacteroidesthetaiotaomicron) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF17137(DUF5110) | 5 | LEU A 164THR A 165GLY A 423ILE A 158ILE A 149 | None | 1.07A | 6ebzC-5djwA:undetectable | 6ebzC-5djwA:7.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ekp | UNCHARACTERIZEDGLYCOSYLTRANSFERASESLL0501 (Synechocystissp. PCC 6803) |
no annotation | 5 | PHE C 22LEU C 25ILE C 63ILE C 9ILE C 7 | None | 1.07A | 6ebzC-5ekpC:undetectable | 6ebzC-5ekpC:12.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f0o | COHESIN SUBUNITPDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P (Lachanceathermotolerans) |
no annotation | 5 | PHE A 435LEU A 438ILE A 477ILE A 460ILE A 484 | None | 1.07A | 6ebzC-5f0oA:undetectable | 6ebzC-5f0oA:6.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hiu | GTPASEACTIVATOR-LIKEPROTEIN (Chaetomiumthermophilum) |
PF11864(DUF3384) | 6 | PHE A 207LEU A 210THR A 211GLY A 276ILE A 274ILE A 262 | PHE A 207 ( 1.3A)LEU A 210 ( 0.5A)THR A 211 ( 0.8A)GLY A 276 ( 0.0A)ILE A 274 ( 0.7A)ILE A 262 ( 0.7A) | 1.04A | 6ebzC-5hiuA:undetectable | 6ebzC-5hiuA:9.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iw9 | BASEPLATE WEDGEPROTEIN GP25 (Escherichiavirus T4) |
PF04965(GPW_gp25) | 5 | GLY A 38ILE A 39PHE A 110ILE A 88ILE A 32 | None | 0.92A | 6ebzC-5iw9A:undetectable | 6ebzC-5iw9A:23.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m0y | CELLULOSOMEANCHORING PROTEINCOHESIN REGION (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 5 | LEU A 85GLY A 81ILE A 128PHE A 48ILE A 42 | NoneP6G A 205 (-3.6A)P6G A 205 (-4.9A)NoneNone | 0.96A | 6ebzC-5m0yA:undetectable | 6ebzC-5m0yA:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mso | CARBOXYLIC ACIDREDUCTASE (Mycobacteriummarinum) |
PF07993(NAD_binding_4) | 5 | LEU A1071ILE A1085PHE A1002ILE A1006ILE A1161 | None | 0.90A | 6ebzC-5msoA:undetectable | 6ebzC-5msoA:6.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5szs | SPIKE GLYCOPROTEIN (HumancoronavirusNL63) |
PF01600(Corona_S1)PF01601(Corona_S2) | 5 | LEU A 151THR A 159ILE A 144ILE A 89ILE A 105 | None | 0.94A | 6ebzC-5szsA:undetectable | 6ebzC-5szsA:4.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ti1 | FUMARYLACETOACETATEHYDROLASE (Paraburkholderiaxenovorans) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 5 | LEU A 249GLY A 368ILE A 370PHE A 424ILE A 316 | None MG A 501 ( 4.7A)NoneNoneNone | 1.01A | 6ebzC-5ti1A:undetectable | 6ebzC-5ti1A:11.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ucd | NAD(P)-DEPENDENTBENZALDEHYDEDEHYDROGENASE (Pseudomonasputida) |
PF00171(Aldedh) | 6 | LEU A 127THR A 128GLY A 132ILE A 134ILE A 159ILE A 142 | None | 1.12A | 6ebzC-5ucdA:undetectable | 6ebzC-5ucdA:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uz5 | 56 KDA U1 SMALLNUCLEARRIBONUCLEOPROTEINCOMPONENT (Saccharomycescerevisiae) |
no annotation | 5 | LEU G 117GLY G 67ILE G 65PHE G 224ILE G 97 | None | 1.07A | 6ebzC-5uz5G:undetectable | 6ebzC-5uz5G:10.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v3s | TWO-COMPONENTINSECTICIDAL PROTEIN16 KDA UNIT (Alcaligenesfaecalis) |
PF06355(Aegerolysin) | 5 | PHE A 97LEU A 113ASP A 111GLY A 86ILE A 138 | None | 1.03A | 6ebzC-5v3sA:undetectable | 6ebzC-5v3sA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z2g | L-AMINO ACID OXIDASE (Naja atra) |
no annotation | 5 | PHE A 398LEU A 401ASP A 402ILE A 344ILE A 409 | None | 1.01A | 6ebzC-5z2gA:undetectable | 6ebzC-5z2gA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6aun | PLA2G6, IPLA2BETA (Cricetulusgriseus) |
no annotation | 5 | PHE A 704LEU A 706ILE A 635PHE A 742ILE A 446 | None | 0.94A | 6ebzC-6aunA:undetectable | 6ebzC-6aunA:23.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6c2h | CYSTATHIONINEBETA-SYNTHASE (Saccharomycescerevisiae) |
no annotation | 5 | SER A 205GLY A 203ILE A 204PHE A 185ILE A 215 | None | 1.05A | 6ebzC-6c2hA:undetectable | 6ebzC-6c2hA:36.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c43 | GAMMA-AMINOBUTYRALDEHYDE DEHYDROGENASE (Salmonellaenterica) |
no annotation | 5 | PHE A 108LEU A 67SER A 73ILE A 74ILE A 191 | None | 0.88A | 6ebzC-6c43A:undetectable | 6ebzC-6c43A:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gct | NEUTRAL AMINO ACIDTRANSPORTER B(0) (Homo sapiens) |
no annotation | 5 | PHE A 393THR A 438GLY A 434ILE A 456ILE A 453 | NoneNoneGLN A 601 ( 4.8A)NoneNone | 1.07A | 6ebzC-6gctA:undetectable | 6ebzC-6gctA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ged | PRGB (Enterococcusfaecalis) |
no annotation | 5 | PHE A 275THR A 549ILE A 369ILE A 418ILE A 523 | None | 1.01A | 6ebzC-6gedA:undetectable | 6ebzC-6gedA:20.24 |