SIMILAR PATTERNS OF AMINO ACIDS FOR 6EBZ_A_DAHA123
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a7j | PHOSPHORIBULOKINASE (Rhodobactersphaeroides) |
PF00485(PRK) | 5 | PHE A 84GLY A 88ILE A 7PHE A 44ILE A 39 | None | 0.82A | 6ebzA-1a7jA:undetectable | 6ebzA-1a7jA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cz3 | DIHYDROFOLATEREDUCTASE (Thermotogamaritima) |
PF00186(DHFR_1) | 5 | PHE A 106THR A 104GLY A 44ILE A 15ILE A 131 | NoneSO4 A 200 (-4.0A)SO4 A 200 (-3.3A)NoneNone | 1.01A | 6ebzA-1cz3A:undetectable | 6ebzA-1cz3A:16.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ecx | AMINOTRANSFERASE (Thermotogamaritima) |
PF00266(Aminotran_5) | 5 | PHE A 299GLY A 304ILE A 349ILE A 369ILE A 372 | None | 1.06A | 6ebzA-1ecxA:undetectable | 6ebzA-1ecxA:10.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eww | ANTIFREEZE PROTEIN (Choristoneurafumiferana) |
PF05264(CfAFP) | 5 | PHE A 87SER A 52GLY A 54ILE A 82ILE A 64 | None | 1.01A | 6ebzA-1ewwA:undetectable | 6ebzA-1ewwA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8r | L-AMINO ACID OXIDASE (Calloselasmarhodostoma) |
PF01593(Amino_oxidase) | 5 | PHE A 381LEU A 384ASP A 385ILE A 327ILE A 392 | None | 1.02A | 6ebzA-1f8rA:undetectable | 6ebzA-1f8rA:9.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g0d | PROTEIN-GLUTAMINEGAMMA-GLUTAMYLTRANSFERASE (Pagrus major) |
PF00868(Transglut_N)PF00927(Transglut_C)PF01841(Transglut_core) | 5 | PHE A 189LEU A 192ASP A 205GLY A 63ILE A 105 | None | 1.07A | 6ebzA-1g0dA:undetectable | 6ebzA-1g0dA:8.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g71 | DNA PRIMASE (Pyrococcusfuriosus) |
PF01896(DNA_primase_S) | 5 | SER A 73GLY A 38PHE A 39ILE A 24ILE A 28 | None | 1.02A | 6ebzA-1g71A:undetectable | 6ebzA-1g71A:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jx2 | MYOSIN-2 HEAVYCHAIN,DYNAMIN-A (Dictyosteliumdiscoideum) |
PF00063(Myosin_head)PF02736(Myosin_N) | 5 | LEU A 540ASP A 541GLY A 530ILE A 528PHE A 477 | None | 1.07A | 6ebzA-1jx2A:undetectable | 6ebzA-1jx2A:7.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kgp | RIBONUCLEOTIDEREDUCTASE PROTEINR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 9 | PHE A 70LEU A 73THR A 74ASP A 77ILE A 118PHE A 119PHE A 176ILE A 195ILE A 198 | NoneNoneNone MN A1001 (-2.7A)NoneNoneNoneNoneNone | 0.46A | 6ebzA-1kgpA:42.2 | 6ebzA-1kgpA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kgp | RIBONUCLEOTIDEREDUCTASE PROTEINR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 70LEU A 73THR A 74ASP A 77SER A 114ILE A 118ILE A 195ILE A 198 | NoneNoneNone MN A1001 (-2.7A)NoneNoneNoneNone | 0.58A | 6ebzA-1kgpA:42.2 | 6ebzA-1kgpA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ogq | POLYGALACTURONASEINHIBITING PROTEIN (Phaseolusvulgaris) |
PF08263(LRRNT_2) | 6 | LEU A 141GLY A 170PHE A 194PHE A 156ILE A 154ILE A 145 | None | 1.29A | 6ebzA-1ogqA:undetectable | 6ebzA-1ogqA:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oh9 | ACETYLGLUTAMATEKINASE (Escherichiacoli) |
PF00696(AA_kinase) | 5 | PHE A 24LEU A 23ILE A 97ILE A 40ILE A 7 | None | 1.05A | 6ebzA-1oh9A:undetectable | 6ebzA-1oh9A:11.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pc3 | PHOSPHATE-BINDINGPROTEIN 1 (Mycobacteriumtuberculosis) |
PF12849(PBP_like_2) | 6 | PHE A 312LEU A 309THR A 308ILE A 58PHE A 49ILE A 79 | None | 1.47A | 6ebzA-1pc3A:undetectable | 6ebzA-1pc3A:11.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pg5 | ASPARTATECARBAMOYLTRANSFERASE (Sulfolobusacidocaldarius) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | LEU A 1GLY A 298PHE A 10ILE A 18ILE A 292 | None | 1.02A | 6ebzA-1pg5A:undetectable | 6ebzA-1pg5A:15.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pm2 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1BETA CHAIN (Escherichiacoli) |
PF00268(Ribonuc_red_sm) | 5 | SER A 121ILE A 125PHE A 212ILE A 231ILE A 234 | None | 0.67A | 6ebzA-1pm2A:28.9 | 6ebzA-1pm2A:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pm2 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1BETA CHAIN (Escherichiacoli) |
PF00268(Ribonuc_red_sm) | 5 | THR A 81SER A 121ILE A 125ILE A 231ILE A 234 | None | 0.49A | 6ebzA-1pm2A:28.9 | 6ebzA-1pm2A:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qqj | FUMARYLACETOACETATEHYDROLASE (Mus musculus) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 5 | LEU A 230GLY A 349ILE A 351PHE A 405ILE A 297 | None CA A 420 ( 4.5A)NoneNoneNone | 1.01A | 6ebzA-1qqjA:undetectable | 6ebzA-1qqjA:9.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1r2f | PROTEIN(RIBONUCLEOTIDEREDUCTASE R2) (Salmonellaenterica) |
PF00268(Ribonuc_red_sm) | 10 | PHE A 60LEU A 63THR A 64ASP A 67SER A 104ILE A 108PHE A 109PHE A 166ILE A 185ILE A 188 | NoneNoneNone FE A 400 (-3.0A)NoneNoneNoneNoneNoneNone | 0.52A | 6ebzA-1r2fA:42.6 | 6ebzA-1r2fA:30.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1suh | EPITHELIAL CADHERIN (Mus musculus) |
PF00028(Cadherin) | 5 | LEU A 21GLY A 58ILE A 53ILE A 96ILE A 7 | None | 1.02A | 6ebzA-1suhA:undetectable | 6ebzA-1suhA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdk | L-AMINO ACID OXIDASE (Gloydius halys) |
PF01593(Amino_oxidase) | 5 | PHE A 381LEU A 384ASP A 385ILE A 327ILE A 392 | None | 0.94A | 6ebzA-1tdkA:undetectable | 6ebzA-1tdkA:10.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 6 | PHE A 65LEU A 68THR A 66ILE A 113PHE A 114ILE A 190 | None | 1.48A | 6ebzA-1uzrA:41.3 | 6ebzA-1uzrA:42.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 10 | PHE A 65LEU A 68THR A 69ASP A 72SER A 109ILE A 113PHE A 114PHE A 171ILE A 190ILE A 193 | NoneNoneNone FE A1292 (-2.5A)NoneNoneNoneNoneNoneNone | 0.52A | 6ebzA-1uzrA:41.3 | 6ebzA-1uzrA:42.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v33 | DNA PRIMASE SMALLSUBUNIT (Pyrococcushorikoshii) |
PF01896(DNA_primase_S) | 5 | SER A 73GLY A 38PHE A 39ILE A 24ILE A 28 | None | 1.02A | 6ebzA-1v33A:undetectable | 6ebzA-1v33A:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vlm | SAM-DEPENDENTMETHYLTRANSFERASE (Thermotogamaritima) |
PF08241(Methyltransf_11) | 5 | LEU A 162GLY A 204ILE A 202PHE A 171ILE A 100 | None | 0.86A | 6ebzA-1vlmA:undetectable | 6ebzA-1vlmA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vme | FLAVOPROTEIN (Thermotogamaritima) |
PF00258(Flavodoxin_1) | 5 | PHE A 165GLY A 227PHE A 10ILE A 15ILE A 9 | None | 1.06A | 6ebzA-1vmeA:undetectable | 6ebzA-1vmeA:12.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xzw | PURPLE ACIDPHOSPHATASE (Ipomoea batatas) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 6 | PHE A 129LEU A 131ILE A 393PHE A 319ILE A 281ILE A 317 | None | 1.44A | 6ebzA-1xzwA:undetectable | 6ebzA-1xzwA:12.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yf2 | TYPE IRESTRICTION-MODIFICATION ENZYME, SSUBUNIT (Methanocaldococcusjannaschii) |
PF01420(Methylase_S) | 5 | LEU A 417THR A 418GLY A 14ILE A 13PHE A 129 | None | 1.02A | 6ebzA-1yf2A:undetectable | 6ebzA-1yf2A:10.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a6o | ISHP608 TRANSPOSASE (Helicobacterpylori) |
PF01797(Y1_Tnp) | 6 | PHE A 80GLY A 76ILE A 71PHE A 75ILE A 21ILE A 113 | None | 1.21A | 6ebzA-2a6oA:undetectable | 6ebzA-2a6oA:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bm3 | SCAFFOLDING DOCKERINBINDING PROTEIN A (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 5 | LEU A 73GLY A 69ILE A 116PHE A 36ILE A 30 | None | 1.00A | 6ebzA-2bm3A:undetectable | 6ebzA-2bm3A:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g0t | CONSERVEDHYPOTHETICAL PROTEIN (Thermotogamaritima) |
PF07755(DUF1611)PF17396(DUF1611_N) | 5 | LEU A 38GLY A 198ILE A 199ILE A 111ILE A 82 | None | 1.00A | 6ebzA-2g0tA:undetectable | 6ebzA-2g0tA:13.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g28 | PYRUVATEDEHYDROGENASE E1COMPONENT (Escherichiacoli) |
PF00456(Transketolase_N) | 5 | PHE A 532LEU A 531GLY A 562ILE A 537ILE A 519 | None | 0.97A | 6ebzA-2g28A:undetectable | 6ebzA-2g28A:7.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gep | SULFITE REDUCTASEHEMOPROTEIN (Escherichiacoli) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | GLY A 89ILE A 392PHE A 122ILE A 112ILE A 99 | None | 1.02A | 6ebzA-2gepA:undetectable | 6ebzA-2gepA:9.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gwm | 65 KDA VIRULENCEPROTEIN (Salmonellaenterica) |
PF03496(ADPrib_exo_Tox) | 5 | LEU A 427THR A 426GLY A 405ILE A 409PHE A 443 | None | 1.02A | 6ebzA-2gwmA:undetectable | 6ebzA-2gwmA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i5g | AMIDOHYDROLASE (Pseudomonasaeruginosa) |
PF01244(Peptidase_M19) | 5 | PHE A 260LEU A 263THR A 264GLY A 277ILE A 279 | None | 1.04A | 6ebzA-2i5gA:undetectable | 6ebzA-2i5gA:12.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ic7 | MALTOSETRANSACETYLASE (Geobacilluskaustophilus) |
PF00132(Hexapep)PF12464(Mac)PF14602(Hexapep_2) | 5 | THR A 150GLY A 134ILE A 97ILE A 109ILE A 145 | None | 1.03A | 6ebzA-2ic7A:undetectable | 6ebzA-2ic7A:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jdx | PROTEIN(L-ARGININE:GLYCINEAMIDINOTRANSFERASE) (Homo sapiens) |
no annotation | 5 | PHE A 383GLY A 387ILE A 388ILE A 311ILE A 315 | None | 1.06A | 6ebzA-2jdxA:undetectable | 6ebzA-2jdxA:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mjp | PYROPHOSPHATASE (Methanocaldococcusjannaschii) |
PF01725(Ham1p_like) | 5 | LEU A 28ILE A 21PHE A 185ILE A 70ILE A 11 | None | 0.94A | 6ebzA-2mjpA:undetectable | 6ebzA-2mjpA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qfe | CALPAIN-7 (Homo sapiens) |
PF01067(Calpain_III) | 5 | LEU A 731ILE A 692PHE A 741ILE A 784ILE A 729 | None BR A 8 ( 4.6A)NoneNoneNone | 1.08A | 6ebzA-2qfeA:undetectable | 6ebzA-2qfeA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rcc | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillushalodurans) |
PF00268(Ribonuc_red_sm) | 5 | LEU A 84SER A 124PHE A 193ILE A 212ILE A 215 | None | 0.71A | 6ebzA-2rccA:27.5 | 6ebzA-2rccA:10.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdw | VACCINIA VIRUSCAPPING ENZYME D1SUBUNIT (Vaccinia virus) |
PF03291(Pox_MCEL) | 6 | LEU A 700THR A 701PHE A 780PHE A 659ILE A 654ILE A 597 | None | 1.19A | 6ebzA-2vdwA:undetectable | 6ebzA-2vdwA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x8a | NUCLEARVALOSIN-CONTAININGPROTEIN-LIKE (Homo sapiens) |
PF00004(AAA) | 5 | LEU A 705GLY A 711PHE A 680ILE A 720ILE A 678 | None | 1.08A | 6ebzA-2x8aA:undetectable | 6ebzA-2x8aA:13.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahx | BETA-GLUCOSIDASE A (Clostridiumcellulovorans) |
PF00232(Glyco_hydro_1) | 5 | PHE A 151GLY A 215ILE A 217ILE A 119ILE A 117 | None | 1.07A | 6ebzA-3ahxA:undetectable | 6ebzA-3ahxA:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c0r | UBIQUITINTHIOESTERASE OTU1 (Saccharomycescerevisiae) |
PF02338(OTU) | 5 | LEU A 138GLY A 182ILE A 192PHE A 130ILE A 129 | None | 0.90A | 6ebzA-3c0rA:undetectable | 6ebzA-3c0rA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cyg | UNCHARACTERIZEDPROTEIN (Fervidobacteriumnodosum) |
PF11738(DUF3298)PF13739(DUF4163) | 5 | PHE A 201GLY A 207ILE A 203PHE A 197ILE A 160 | None | 1.02A | 6ebzA-3cygA:undetectable | 6ebzA-3cygA:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e5d | PUTATIVE GLYOXALASEI (Listeriamonocytogenes) |
PF00903(Glyoxalase) | 5 | LEU A 87THR A 88PHE A 24ILE A 76ILE A 122 | None | 1.05A | 6ebzA-3e5dA:undetectable | 6ebzA-3e5dA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e74 | ALLANTOINASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 5 | PHE A 388GLY A 10ILE A 7ILE A 30ILE A 33 | None | 1.07A | 6ebzA-3e74A:undetectable | 6ebzA-3e74A:9.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9k | KYNURENINASE (Homo sapiens) |
PF00266(Aminotran_5) | 5 | LEU A 368THR A 365GLY A 400ILE A 405ILE A 390 | None | 1.01A | 6ebzA-3e9kA:undetectable | 6ebzA-3e9kA:10.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgx | RBSTP2171 (Geobacillusstearothermophilus) |
no annotation | 5 | LEU A 91THR A 92ILE A 73PHE A 70ILE A 23 | None | 0.95A | 6ebzA-3fgxA:undetectable | 6ebzA-3fgxA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETA (Moorellathermoacetica) |
PF03063(Prismane) | 5 | PHE A 174LEU A 171GLY A 207ILE A 208ILE A 247 | None | 0.92A | 6ebzA-3i04A:undetectable | 6ebzA-3i04A:7.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iwt | 178AA LONGHYPOTHETICALMOLYBDENUM COFACTORBIOSYNTHESIS PROTEINB (Sulfurisphaeratokodaii) |
PF00994(MoCF_biosynth) | 5 | LEU A 149GLY A 92PHE A 73ILE A 69ILE A 23 | None | 1.03A | 6ebzA-3iwtA:undetectable | 6ebzA-3iwtA:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jcu | OXYGEN-EVOLVINGENHANCER PROTEIN 1,CHLOROPLASTIC (Spinaciaoleracea) |
PF01716(MSP) | 6 | PHE O 301LEU O 285THR O 284ILE O 321PHE O 134ILE O 213 | None | 1.41A | 6ebzA-3jcuO:undetectable | 6ebzA-3jcuO:12.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kg7 | CURH (Lyngbyamajuscula) |
PF14765(PS-DH) | 5 | LEU A1166THR A1165ILE A1195ILE A1135ILE A 985 | None | 1.00A | 6ebzA-3kg7A:undetectable | 6ebzA-3kg7A:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kzp | PUTATIVE DIGUANYLATECYCLASE/PHOSPHODIESTERASE (Listeriamonocytogenes) |
PF00563(EAL) | 5 | LEU A 96ILE A 137PHE A 63ILE A 77ILE A 103 | None | 1.08A | 6ebzA-3kzpA:undetectable | 6ebzA-3kzpA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk6 | LIPOPROTEIN YBBD (Bacillussubtilis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 5 | PHE A 604THR A 471GLY A 599ILE A 603ILE A 455 | None | 1.07A | 6ebzA-3lk6A:undetectable | 6ebzA-3lk6A:8.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk6 | LIPOPROTEIN YBBD (Bacillussubtilis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 5 | PHE A 604THR A 471GLY A 599ILE A 603ILE A 457 | None | 0.85A | 6ebzA-3lk6A:undetectable | 6ebzA-3lk6A:8.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 70LEU A 73THR A 74ASP A 77ILE A 118PHE A 176ILE A 195ILE A 198 | NoneNoneNoneMN3 A1001 (-2.2A)NoneNoneNoneNone | 0.65A | 6ebzA-3mjoA:41.1 | 6ebzA-3mjoA:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 70LEU A 73THR A 74ASP A 77SER A 114ILE A 118ILE A 195ILE A 198 | NoneNoneNoneMN3 A1001 (-2.2A)NoneNoneNoneNone | 0.65A | 6ebzA-3mjoA:41.1 | 6ebzA-3mjoA:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 70LEU A 73THR A 74ILE A 118PHE A 119PHE A 176ILE A 195ILE A 198 | None | 0.57A | 6ebzA-3mjoA:41.1 | 6ebzA-3mjoA:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n00 | REV-ERBA-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 545THR A 541ILE A 299PHE A 300ILE A 457 | None | 1.06A | 6ebzA-3n00A:undetectable | 6ebzA-3n00A:15.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n3b | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2SUBUNIT BETA (Escherichiacoli) |
no annotation | 9 | PHE B 60LEU B 63THR B 64ASP B 67ILE B 108PHE B 109PHE B 166ILE B 185ILE B 188 | NoneNoneNone MN B 320 (-2.8A)NoneNoneNoneNoneNone | 0.44A | 6ebzA-3n3bB:41.7 | 6ebzA-3n3bB:30.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n3b | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2SUBUNIT BETA (Escherichiacoli) |
no annotation | 9 | PHE B 60LEU B 63THR B 64ASP B 67SER B 104ILE B 108PHE B 166ILE B 185ILE B 188 | NoneNoneNone MN B 320 (-2.8A)NoneNoneNoneNoneNone | 0.63A | 6ebzA-3n3bB:41.7 | 6ebzA-3n3bB:30.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3njx | RHAMNOGALACTURONASEB (Aspergillusaculeatus) |
PF09284(RhgB_N)PF14683(CBM-like)PF14686(fn3_3) | 5 | LEU A 506GLY A 420ILE A 419ILE A 481ILE A 403 | None | 1.03A | 6ebzA-3njxA:undetectable | 6ebzA-3njxA:9.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojl | CAP5O (Staphylococcusaureus) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | LEU A 221THR A 222GLY A 251ILE A 215ILE A 236 | None | 1.08A | 6ebzA-3ojlA:undetectable | 6ebzA-3ojlA:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojl | CAP5O (Staphylococcusaureus) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | LEU A 221THR A 222GLY A 251ILE A 247ILE A 236 | None | 0.98A | 6ebzA-3ojlA:undetectable | 6ebzA-3ojlA:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sun | DNA POLYMERASE (Escherichiavirus RB69) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | PHE A 841GLY A 807ILE A 846ILE A 858ILE A 815 | None | 1.04A | 6ebzA-3sunA:undetectable | 6ebzA-3sunA:6.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3un6 | HYPOTHETICAL PROTEINSAOUHSC_00137 (Staphylococcusaureus) |
PF13379(NMT1_2) | 5 | LEU A 225GLY A 85PHE A 240ILE A 37ILE A 39 | None | 1.06A | 6ebzA-3un6A:undetectable | 6ebzA-3un6A:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w1s | AUTOPHAGY PROTEIN 5 (Saccharomycescerevisiae) |
PF04106(APG5) | 5 | LEU A 263THR A 228ILE A 257ILE A 279ILE A 236 | None | 1.04A | 6ebzA-3w1sA:undetectable | 6ebzA-3w1sA:13.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wuy | NITRILASE (Synechocystissp. PCC 6803) |
PF00795(CN_hydrolase) | 5 | LEU A 106GLY A 127PHE A 51ILE A 49ILE A 38 | None | 1.06A | 6ebzA-3wuyA:undetectable | 6ebzA-3wuyA:14.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wvo | CRISPR-ASSOCIATEDPROTEIN, CSE1 FAMILY (Thermobifidafusca) |
PF09481(CRISPR_Cse1) | 6 | LEU A 213GLY A 68ILE A 66PHE A 34ILE A 93ILE A 61 | None | 1.44A | 6ebzA-3wvoA:3.3 | 6ebzA-3wvoA:8.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4az7 | BETA-N-ACETYLHEXOSAMINIDASE (Streptococcuspneumoniae) |
PF00728(Glyco_hydro_20) | 5 | THR A 217GLY A 511ILE A 510ILE A 354ILE A 289 | None | 1.06A | 6ebzA-4az7A:undetectable | 6ebzA-4az7A:9.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmr | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillus cereus) |
PF00268(Ribonuc_red_sm) | 8 | LEU A 58THR A 59ASP A 62ILE A 103PHE A 104PHE A 169ILE A 188ILE A 191 | NoneNoneFE2 A1323 (-2.4A)NoneNoneNoneNoneNone | 0.50A | 6ebzA-4bmrA:38.6 | 6ebzA-4bmrA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmr | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillus cereus) |
PF00268(Ribonuc_red_sm) | 8 | LEU A 58THR A 59ASP A 62SER A 99ILE A 103PHE A 169ILE A 188ILE A 191 | NoneNoneFE2 A1323 (-2.4A)NoneNoneNoneNoneNone | 0.65A | 6ebzA-4bmrA:38.6 | 6ebzA-4bmrA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ckb | MRNA-CAPPING ENZYMECATALYTIC SUBUNIT (Vaccinia virus) |
PF03291(Pox_MCEL)PF10640(Pox_ATPase-GT) | 6 | LEU A 700THR A 701PHE A 780PHE A 659ILE A 654ILE A 597 | None | 1.14A | 6ebzA-4ckbA:undetectable | 6ebzA-4ckbA:6.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cp6 | CHOLINE BINDINGPROTEIN PCPA (Streptococcuspneumoniae) |
PF13306(LRR_5) | 5 | LEU A 345GLY A 371ILE A 374PHE A 336ILE A 331 | None | 1.01A | 6ebzA-4cp6A:undetectable | 6ebzA-4cp6A:12.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dr0 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillussubtilis) |
PF00268(Ribonuc_red_sm) | 9 | LEU A 62THR A 63ASP A 66SER A 104ILE A 108PHE A 109PHE A 172ILE A 191ILE A 194 | NoneNone MN A 402 (-2.3A)NoneNoneNoneNoneNoneNone | 0.53A | 6ebzA-4dr0A:38.8 | 6ebzA-4dr0A:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fin | ETTA (YJJK) ABCFFAMILY PROTEIN (Escherichiacoli) |
PF00005(ABC_tran)PF12848(ABC_tran_Xtn) | 5 | LEU A 365THR A 364GLY A 359ILE A 354ILE A 497 | NoneNoneSO4 A 603 (-3.3A)NoneNone | 1.07A | 6ebzA-4finA:undetectable | 6ebzA-4finA:10.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 87GLY A 106ILE A 82ILE A 96ILE A 119 | None | 0.94A | 6ebzA-4fs7A:undetectable | 6ebzA-4fs7A:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 133GLY A 152ILE A 128ILE A 142ILE A 164 | None | 0.97A | 6ebzA-4fs7A:undetectable | 6ebzA-4fs7A:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 336GLY A 355ILE A 331ILE A 345ILE A 368 | None | 0.78A | 6ebzA-4fs7A:undetectable | 6ebzA-4fs7A:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g38 | SULFITE REDUCTASE[NADPH] HEMOPROTEINBETA-COMPONENT (Escherichiacoli) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | GLY A 89ILE A 392PHE A 122ILE A 112ILE A 99 | None | 0.99A | 6ebzA-4g38A:undetectable | 6ebzA-4g38A:8.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdu | AEROTOLERANCE-RELATED MEMBRANE PROTEIN (Bacteroidesfragilis) |
PF00092(VWA) | 5 | ASP A 129GLY A 132ILE A 94ILE A 283ILE A 287 | None | 0.81A | 6ebzA-4jduA:undetectable | 6ebzA-4jduA:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3y | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 5 | PHE A 374LEU A 397ILE A 404PHE A 446ILE A 444 | None | 1.07A | 6ebzA-4k3yA:undetectable | 6ebzA-4k3yA:11.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m1e | PURINE NUCLEOSIDEPHOSPHORYLASE (Planctopiruslimnophila) |
PF01048(PNP_UDP_1) | 5 | PHE A 231LEU A 110ILE A 129ILE A 269ILE A 273 | None | 1.06A | 6ebzA-4m1eA:undetectable | 6ebzA-4m1eA:14.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n83 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Streptococcussanguinis) |
PF00268(Ribonuc_red_sm) | 10 | PHE A 59LEU A 62THR A 63ASP A 66SER A 103ILE A 107PHE A 108PHE A 165ILE A 184ILE A 187 | NoneNoneNone MN A 402 (-2.8A)NoneNoneNoneNoneNoneNone | 0.49A | 6ebzA-4n83A:38.8 | 6ebzA-4n83A:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p5w | CALCIUM-BINDINGMITOCHONDRIALCARRIER PROTEINARALAR2,CALCIUM-BINDING MITOCHONDRIALCARRIER PROTEINARALAR2 (Homo sapiens) |
no annotation | 5 | THR A 265GLY A 222ILE A 271PHE A 254ILE A 233 | None | 0.93A | 6ebzA-4p5wA:undetectable | 6ebzA-4p5wA:11.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qku | HYDROLASE (Burkholderiacenocepacia) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 5 | LEU A 245GLY A 364ILE A 366PHE A 420ILE A 312 | None | 0.99A | 6ebzA-4qkuA:undetectable | 6ebzA-4qkuA:12.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xru | HEN1 (Capnocytophagagingivalis) |
no annotation | 5 | PHE C 84LEU C 87ILE C 79ILE C 5ILE C 116 | None | 1.02A | 6ebzA-4xruC:undetectable | 6ebzA-4xruC:11.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aex | AMMONIUM TRANSPORTERMEP2 (Saccharomycescerevisiae) |
PF00909(Ammonium_transp) | 5 | LEU A 56GLY A 142ILE A 49ILE A 297ILE A 347 | None | 1.05A | 6ebzA-5aexA:2.6 | 6ebzA-5aexA:9.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5djw | ALPHA-GLUCOSIDASE II (Bacteroidesthetaiotaomicron) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF17137(DUF5110) | 5 | LEU A 164THR A 165GLY A 423ILE A 158ILE A 149 | None | 1.07A | 6ebzA-5djwA:undetectable | 6ebzA-5djwA:7.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gr8 | LEUCINE-RICH REPEATRECEPTOR-LIKEPROTEIN KINASE PEPR1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | PHE A 168LEU A 173SER A 218GLY A 192ILE A 191 | None | 0.96A | 6ebzA-5gr8A:undetectable | 6ebzA-5gr8A:7.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hiu | GTPASEACTIVATOR-LIKEPROTEIN (Chaetomiumthermophilum) |
PF11864(DUF3384) | 6 | PHE A 207LEU A 210THR A 211GLY A 276ILE A 274ILE A 262 | PHE A 207 ( 1.3A)LEU A 210 ( 0.5A)THR A 211 ( 0.8A)GLY A 276 ( 0.0A)ILE A 274 ( 0.7A)ILE A 262 ( 0.7A) | 0.98A | 6ebzA-5hiuA:undetectable | 6ebzA-5hiuA:9.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iw9 | BASEPLATE WEDGEPROTEIN GP25 (Escherichiavirus T4) |
PF04965(GPW_gp25) | 5 | GLY A 38ILE A 39PHE A 110ILE A 88ILE A 32 | None | 0.97A | 6ebzA-5iw9A:undetectable | 6ebzA-5iw9A:23.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m0y | CELLULOSOMEANCHORING PROTEINCOHESIN REGION (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 5 | LEU A 85GLY A 81ILE A 128PHE A 48ILE A 42 | NoneP6G A 205 (-3.6A)P6G A 205 (-4.9A)NoneNone | 0.98A | 6ebzA-5m0yA:undetectable | 6ebzA-5m0yA:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mso | CARBOXYLIC ACIDREDUCTASE (Mycobacteriummarinum) |
PF07993(NAD_binding_4) | 5 | LEU A1071ILE A1085PHE A1002ILE A1006ILE A1161 | None | 0.88A | 6ebzA-5msoA:undetectable | 6ebzA-5msoA:6.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5szs | SPIKE GLYCOPROTEIN (HumancoronavirusNL63) |
PF01600(Corona_S1)PF01601(Corona_S2) | 5 | LEU A 151THR A 159ILE A 144ILE A 89ILE A 105 | None | 0.92A | 6ebzA-5szsA:undetectable | 6ebzA-5szsA:4.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ti1 | FUMARYLACETOACETATEHYDROLASE (Paraburkholderiaxenovorans) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 5 | LEU A 249GLY A 368ILE A 370PHE A 424ILE A 316 | None MG A 501 ( 4.7A)NoneNoneNone | 0.97A | 6ebzA-5ti1A:undetectable | 6ebzA-5ti1A:11.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ucd | NAD(P)-DEPENDENTBENZALDEHYDEDEHYDROGENASE (Pseudomonasputida) |
PF00171(Aldedh) | 6 | LEU A 127THR A 128GLY A 132ILE A 134ILE A 159ILE A 142 | None | 1.15A | 6ebzA-5ucdA:undetectable | 6ebzA-5ucdA:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v3s | TWO-COMPONENTINSECTICIDAL PROTEIN16 KDA UNIT (Alcaligenesfaecalis) |
PF06355(Aegerolysin) | 5 | PHE A 97LEU A 113ASP A 111GLY A 86ILE A 138 | None | 1.01A | 6ebzA-5v3sA:undetectable | 6ebzA-5v3sA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z2g | L-AMINO ACID OXIDASE (Naja atra) |
no annotation | 5 | PHE A 398LEU A 401ASP A 402ILE A 344ILE A 409 | None | 0.98A | 6ebzA-5z2gA:undetectable | 6ebzA-5z2gA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ged | PRGB (Enterococcusfaecalis) |
no annotation | 5 | PHE A 275THR A 549ILE A 369ILE A 418ILE A 523 | None | 1.04A | 6ebzA-6gedA:undetectable | 6ebzA-6gedA:20.24 |