SIMILAR PATTERNS OF AMINO ACIDS FOR 6EBP_D_DAHD123_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ecx AMINOTRANSFERASE

(Thermotoga
maritima)
PF00266
(Aminotran_5)
5 PHE A 299
GLY A 304
ILE A 349
ILE A 369
ILE A 372
None
1.06A 6ebpD-1ecxA:
undetectable
6ebpD-1ecxA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eww ANTIFREEZE PROTEIN

(Choristoneura
fumiferana)
PF05264
(CfAFP)
5 PHE A  87
SER A  52
GLY A  54
ILE A  82
ILE A  64
None
1.02A 6ebpD-1ewwA:
undetectable
6ebpD-1ewwA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8r L-AMINO ACID OXIDASE

(Calloselasma
rhodostoma)
PF01593
(Amino_oxidase)
5 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
None
1.04A 6ebpD-1f8rA:
undetectable
6ebpD-1f8rA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g0d PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE


(Pagrus major)
PF00868
(Transglut_N)
PF00927
(Transglut_C)
PF01841
(Transglut_core)
5 PHE A 189
LEU A 192
ASP A 205
GLY A  63
ILE A 105
None
1.06A 6ebpD-1g0dA:
undetectable
6ebpD-1g0dA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g71 DNA PRIMASE

(Pyrococcus
furiosus)
PF01896
(DNA_primase_S)
5 SER A  73
GLY A  38
PHE A  39
ILE A  24
ILE A  28
None
1.00A 6ebpD-1g71A:
undetectable
6ebpD-1g71A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
8 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
ILE A 195
ILE A 198
None
None
None
MN  A1001 (-2.7A)
None
None
None
None
0.43A 6ebpD-1kgpA:
42.2
6ebpD-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
8 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 195
ILE A 198
None
None
None
MN  A1001 (-2.7A)
None
None
None
None
0.62A 6ebpD-1kgpA:
42.2
6ebpD-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kru GALACTOSIDE
O-ACETYLTRANSFERASE


(Escherichia
coli)
PF00132
(Hexapep)
PF12464
(Mac)
PF14602
(Hexapep_2)
5 LEU A  88
ILE A  51
PHE A  36
ILE A  78
ILE A  76
None
1.11A 6ebpD-1kruA:
undetectable
6ebpD-1kruA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqt POLYPROTEIN CAPSID
PROTEIN


(Enterovirus B)
PF00073
(Rhv)
5 PHE C  85
LEU C  95
THR C  88
GLY C 188
ILE C 114
None
1.05A 6ebpD-1mqtC:
undetectable
6ebpD-1mqtC:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ogq POLYGALACTURONASE
INHIBITING PROTEIN


(Phaseolus
vulgaris)
PF08263
(LRRNT_2)
5 LEU A 141
GLY A 170
PHE A 194
ILE A 154
ILE A 145
None
1.08A 6ebpD-1ogqA:
undetectable
6ebpD-1ogqA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oh9 ACETYLGLUTAMATE
KINASE


(Escherichia
coli)
PF00696
(AA_kinase)
5 PHE A  24
LEU A  23
ILE A  97
ILE A  40
ILE A   7
None
1.03A 6ebpD-1oh9A:
undetectable
6ebpD-1oh9A:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pc3 PHOSPHATE-BINDING
PROTEIN 1


(Mycobacterium
tuberculosis)
PF12849
(PBP_like_2)
6 PHE A 312
LEU A 309
THR A 308
ILE A  58
PHE A  49
ILE A  79
None
1.49A 6ebpD-1pc3A:
undetectable
6ebpD-1pc3A:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pm2 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
BETA CHAIN


(Escherichia
coli)
PF00268
(Ribonuc_red_sm)
5 THR A  81
SER A 121
ILE A 125
ILE A 231
ILE A 234
None
0.51A 6ebpD-1pm2A:
29.0
6ebpD-1pm2A:
14.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1r2f PROTEIN
(RIBONUCLEOTIDE
REDUCTASE R2)


(Salmonella
enterica)
PF00268
(Ribonuc_red_sm)
8 PHE A  60
LEU A  63
THR A  64
ASP A  67
ILE A 108
PHE A 109
ILE A 185
ILE A 188
None
None
None
FE  A 400 (-3.0A)
None
None
None
None
0.28A 6ebpD-1r2fA:
42.6
6ebpD-1r2fA:
30.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1r2f PROTEIN
(RIBONUCLEOTIDE
REDUCTASE R2)


(Salmonella
enterica)
PF00268
(Ribonuc_red_sm)
8 PHE A  60
LEU A  63
THR A  64
ASP A  67
SER A 104
ILE A 108
ILE A 185
ILE A 188
None
None
None
FE  A 400 (-3.0A)
None
None
None
None
0.57A 6ebpD-1r2fA:
42.6
6ebpD-1r2fA:
30.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1suh EPITHELIAL CADHERIN

(Mus musculus)
PF00028
(Cadherin)
5 LEU A  21
GLY A  58
ILE A  53
ILE A  96
ILE A   7
None
0.97A 6ebpD-1suhA:
undetectable
6ebpD-1suhA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1suw PROBABLE INORGANIC
POLYPHOSPHATE/ATP-NA
D KINASE


(Archaeoglobus
fulgidus)
PF01513
(NAD_kinase)
5 LEU A  76
THR A  77
SER A  45
GLY A  47
ILE A  65
None
1.11A 6ebpD-1suwA:
undetectable
6ebpD-1suwA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdk L-AMINO ACID OXIDASE

(Gloydius halys)
PF01593
(Amino_oxidase)
5 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
None
0.96A 6ebpD-1tdkA:
undetectable
6ebpD-1tdkA:
10.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1uzr RIBONUCLEOTIDE
REDUCTASE R2-2 SMALL
SUBUNIT


(Mycobacterium
tuberculosis)
PF00268
(Ribonuc_red_sm)
9 PHE A  65
LEU A  68
THR A  69
ASP A  72
SER A 109
ILE A 113
PHE A 114
ILE A 190
ILE A 193
None
None
None
FE  A1292 (-2.5A)
None
None
None
None
None
0.45A 6ebpD-1uzrA:
40.9
6ebpD-1uzrA:
42.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v33 DNA PRIMASE SMALL
SUBUNIT


(Pyrococcus
horikoshii)
PF01896
(DNA_primase_S)
5 SER A  73
GLY A  38
PHE A  39
ILE A  24
ILE A  28
None
1.00A 6ebpD-1v33A:
undetectable
6ebpD-1v33A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vlm SAM-DEPENDENT
METHYLTRANSFERASE


(Thermotoga
maritima)
PF08241
(Methyltransf_11)
5 LEU A 162
GLY A 204
ILE A 202
PHE A 171
ILE A 100
None
0.86A 6ebpD-1vlmA:
undetectable
6ebpD-1vlmA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wvg CDP-GLUCOSE
4,6-DEHYDRATASE


(Salmonella
enterica)
PF16363
(GDP_Man_Dehyd)
5 THR A 325
ILE A 277
PHE A 276
ILE A 199
ILE A 331
None
1.12A 6ebpD-1wvgA:
undetectable
6ebpD-1wvgA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y6l UBIQUITIN-CONJUGATIN
G ENZYME E2E2


(Homo sapiens)
PF00179
(UQ_con)
5 SER A  35
GLY A  24
ILE A  54
ILE A 106
ILE A  37
None
1.10A 6ebpD-1y6lA:
undetectable
6ebpD-1y6lA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a6o ISHP608 TRANSPOSASE

(Helicobacter
pylori)
PF01797
(Y1_Tnp)
6 PHE A  80
GLY A  76
ILE A  71
PHE A  75
ILE A  21
ILE A 113
None
1.18A 6ebpD-2a6oA:
undetectable
6ebpD-2a6oA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bx6 XRP2 PROTEIN

(Homo sapiens)
PF07986
(TBCC)
5 PHE A  62
GLY A  94
ILE A  74
ILE A  64
ILE A  83
None
1.12A 6ebpD-2bx6A:
undetectable
6ebpD-2bx6A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fsv NAD(P)
TRANSHYDROGENASE
SUBUNIT BETA


(Rhodospirillum
rubrum)
PF02233
(PNTB)
5 PHE C 126
LEU C 161
GLY C 129
ILE C 128
ILE C 198
None
None
NAP  C 700 (-3.8A)
None
None
1.09A 6ebpD-2fsvC:
undetectable
6ebpD-2fsvC:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g0t CONSERVED
HYPOTHETICAL PROTEIN


(Thermotoga
maritima)
PF07755
(DUF1611)
PF17396
(DUF1611_N)
5 LEU A  38
GLY A 198
ILE A 199
ILE A 111
ILE A  82
None
0.99A 6ebpD-2g0tA:
undetectable
6ebpD-2g0tA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gb4 THIOPURINE
S-METHYLTRANSFERASE


(Mus musculus)
PF05724
(TPMT)
5 PHE A  61
GLY A 139
ILE A 138
ILE A 130
ILE A 164
None
None
None
SAH  A 300 (-4.5A)
None
1.07A 6ebpD-2gb4A:
undetectable
6ebpD-2gb4A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnh DNA POLYMERASE III
ALPHA SUBUNIT


(Escherichia
coli)
PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6)
5 LEU A 879
GLY A 840
ILE A 838
ILE A 816
ILE A 849
None
1.10A 6ebpD-2hnhA:
undetectable
6ebpD-2hnhA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iue INTEGRIN BETA-2-LIKE
PROTEIN


(Mus musculus)
PF00362
(Integrin_beta)
5 LEU A  26
ASP A  29
ILE A  43
PHE A  66
ILE A 205
None
1.13A 6ebpD-2iueA:
undetectable
6ebpD-2iueA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jdx PROTEIN
(L-ARGININE:GLYCINE
AMIDINOTRANSFERASE)


(Homo sapiens)
no annotation 5 PHE A 383
GLY A 387
ILE A 388
ILE A 311
ILE A 315
None
1.08A 6ebpD-2jdxA:
undetectable
6ebpD-2jdxA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r77 PHOSPHATIDYLETHANOLA
MINE-BINDING
PROTEIN, PUTATIVE


(Plasmodium
falciparum)
PF01161
(PBP)
5 PHE A  76
GLY A 198
ILE A 151
ILE A  74
ILE A  48
None
1.12A 6ebpD-2r77A:
undetectable
6ebpD-2r77A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v73 PUTATIVE
EXO-ALPHA-SIALIDASE


(Clostridium
perfringens)
PF02973
(Sialidase)
5 LEU A  57
GLY A 147
ILE A 146
ILE A 169
ILE A  40
None
1.04A 6ebpD-2v73A:
undetectable
6ebpD-2v73A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w0m SSO2452

(Sulfolobus
solfataricus)
PF06745
(ATPase)
5 LEU A  15
GLY A   8
ILE A   9
ILE A 202
ILE A 187
None
1.13A 6ebpD-2w0mA:
undetectable
6ebpD-2w0mA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahx BETA-GLUCOSIDASE A

(Clostridium
cellulovorans)
PF00232
(Glyco_hydro_1)
5 PHE A 151
GLY A 215
ILE A 217
ILE A 119
ILE A 117
None
1.07A 6ebpD-3ahxA:
undetectable
6ebpD-3ahxA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1


(Homo sapiens)
PF00179
(UQ_con)
5 LEU A 155
GLY A  85
ILE A  83
ILE A 130
ILE A 124
None
None
None
GOL  A 200 (-3.7A)
None
1.09A 6ebpD-3bzhA:
undetectable
6ebpD-3bzhA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bzh UBIQUITIN-CONJUGATIN
G ENZYME E2 E1


(Homo sapiens)
PF00179
(UQ_con)
5 SER A  81
GLY A  70
ILE A 100
ILE A 152
ILE A  83
None
1.11A 6ebpD-3bzhA:
undetectable
6ebpD-3bzhA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6j PUTATIVE HALOACID
DEHALOGENASE-LIKE
HYDROLASE


(Bacteroides
fragilis)
PF13419
(HAD_2)
5 THR A  13
SER A 109
ILE A 108
ILE A 132
ILE A 116
None
PO4  A 251 (-2.6A)
None
None
None
1.09A 6ebpD-3d6jA:
undetectable
6ebpD-3d6jA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e74 ALLANTOINASE

(Escherichia
coli)
PF01979
(Amidohydro_1)
5 PHE A 388
GLY A  10
ILE A   7
ILE A  30
ILE A  33
None
1.06A 6ebpD-3e74A:
undetectable
6ebpD-3e74A:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e9k KYNURENINASE

(Homo sapiens)
PF00266
(Aminotran_5)
5 LEU A 368
THR A 365
GLY A 400
ILE A 405
ILE A 390
None
0.96A 6ebpD-3e9kA:
undetectable
6ebpD-3e9kA:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgx RBSTP2171

(Geobacillus
stearothermophilus)
no annotation 5 LEU A  91
THR A  92
ILE A  73
PHE A  70
ILE A  23
None
0.93A 6ebpD-3fgxA:
undetectable
6ebpD-3fgxA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA


(Moorella
thermoacetica)
PF03063
(Prismane)
5 PHE A 174
LEU A 171
GLY A 207
ILE A 208
ILE A 247
None
0.99A 6ebpD-3i04A:
undetectable
6ebpD-3i04A:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ial PROLYL-TRNA
SYNTHETASE


(Giardia
intestinalis)
PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF09180
(ProRS-C_1)
5 LEU A 356
THR A 355
ILE A 419
ILE A 390
ILE A 328
None
1.10A 6ebpD-3ialA:
undetectable
6ebpD-3ialA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kg7 CURH

(Lyngbya
majuscula)
PF14765
(PS-DH)
5 LEU A1166
THR A1165
ILE A1195
ILE A1135
ILE A 985
None
1.00A 6ebpD-3kg7A:
undetectable
6ebpD-3kg7A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kxi GTP-BINDING PROTEIN
(HFLX)


(Sulfolobus
solfataricus)
PF01926
(MMR_HSR1)
PF13167
(GTP-bdg_N)
PF16360
(GTP-bdg_M)
5 LEU A 252
THR A 251
ILE A  93
ILE A 237
ILE A 240
None
1.12A 6ebpD-3kxiA:
undetectable
6ebpD-3kxiA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lk6 LIPOPROTEIN YBBD

(Bacillus
subtilis)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
5 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 455
None
1.08A 6ebpD-3lk6A:
undetectable
6ebpD-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lk6 LIPOPROTEIN YBBD

(Bacillus
subtilis)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
5 PHE A 604
THR A 471
GLY A 599
ILE A 603
ILE A 457
None
0.87A 6ebpD-3lk6A:
undetectable
6ebpD-3lk6A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lkb PROBABLE
BRANCHED-CHAIN AMINO
ACID ABC
TRANSPORTER, AMINO
ACID BINDING PROTEIN


(Thermus
thermophilus)
PF13458
(Peripla_BP_6)
5 PHE A  67
THR A  63
SER A  81
PHE A  11
ILE A  94
None
1.09A 6ebpD-3lkbA:
undetectable
6ebpD-3lkbA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3me5 CYTOSINE-SPECIFIC
METHYLTRANSFERASE


(Shigella
flexneri)
PF00145
(DNA_methylase)
5 PHE A 103
SER A 105
GLY A 107
ILE A 106
PHE A  87
None
1.10A 6ebpD-3me5A:
undetectable
6ebpD-3me5A:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
7 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
ILE A 195
ILE A 198
None
None
None
MN3  A1001 (-2.2A)
None
None
None
0.56A 6ebpD-3mjoA:
40.8
6ebpD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
7 PHE A  70
LEU A  73
THR A  74
ILE A 118
PHE A 119
ILE A 195
ILE A 198
None
0.37A 6ebpD-3mjoA:
40.8
6ebpD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F


(Corynebacterium
ammoniagenes)
PF00268
(Ribonuc_red_sm)
7 PHE A  70
LEU A  73
THR A  74
SER A 114
ILE A 118
ILE A 195
ILE A 198
None
0.60A 6ebpD-3mjoA:
40.8
6ebpD-3mjoA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n00 REV-ERBA-ALPHA

(Homo sapiens)
PF00104
(Hormone_recep)
5 LEU A 545
THR A 541
ILE A 299
PHE A 300
ILE A 457
None
1.08A 6ebpD-3n00A:
undetectable
6ebpD-3n00A:
15.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA


(Escherichia
coli)
no annotation 7 PHE B  60
LEU B  63
ASP B  67
SER B 104
ILE B 108
ILE B 185
ILE B 188
None
None
MN  B 320 (-2.8A)
None
None
None
None
0.70A 6ebpD-3n3bB:
41.7
6ebpD-3n3bB:
30.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3n3b RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
SUBUNIT BETA


(Escherichia
coli)
no annotation 8 PHE B  60
LEU B  63
THR B  64
ASP B  67
ILE B 108
PHE B 109
ILE B 185
ILE B 188
None
None
None
MN  B 320 (-2.8A)
None
None
None
None
0.45A 6ebpD-3n3bB:
41.7
6ebpD-3n3bB:
30.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nas BETA-PHOSPHOGLUCOMUT
ASE


(Bacillus
subtilis)
PF13419
(HAD_2)
5 LEU A   8
ASP A   7
GLY A 111
ILE A 135
PHE A 132
None
1.13A 6ebpD-3nasA:
undetectable
6ebpD-3nasA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nd0 SLL0855 PROTEIN

(Synechocystis
sp. PCC 6803)
PF00654
(Voltage_CLC)
5 THR A 399
GLY A 196
ILE A 195
ILE A 148
ILE A 105
None
1.13A 6ebpD-3nd0A:
undetectable
6ebpD-3nd0A:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3njx RHAMNOGALACTURONASE
B


(Aspergillus
aculeatus)
PF09284
(RhgB_N)
PF14683
(CBM-like)
PF14686
(fn3_3)
5 LEU A 506
GLY A 420
ILE A 419
ILE A 481
ILE A 403
None
1.00A 6ebpD-3njxA:
undetectable
6ebpD-3njxA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ojl CAP5O

(Staphylococcus
aureus)
PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N)
5 LEU A 221
THR A 222
GLY A 251
ILE A 215
ILE A 236
None
1.11A 6ebpD-3ojlA:
undetectable
6ebpD-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ojl CAP5O

(Staphylococcus
aureus)
PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N)
5 LEU A 221
THR A 222
GLY A 251
ILE A 247
ILE A 236
None
0.98A 6ebpD-3ojlA:
undetectable
6ebpD-3ojlA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sun DNA POLYMERASE

(Escherichia
virus RB69)
PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1)
5 PHE A 841
GLY A 807
ILE A 846
ILE A 858
ILE A 815
None
1.07A 6ebpD-3sunA:
undetectable
6ebpD-3sunA:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsw TIGHT JUNCTION
PROTEIN ZO-1


(Homo sapiens)
PF00595
(PDZ)
PF00625
(Guanylate_kin)
PF07653
(SH3_2)
5 LEU A 549
THR A 548
ASP A 547
GLY A 440
ILE A 445
None
1.13A 6ebpD-3tswA:
undetectable
6ebpD-3tswA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4az7 BETA-N-ACETYLHEXOSAM
INIDASE


(Streptococcus
pneumoniae)
PF00728
(Glyco_hydro_20)
5 THR A 217
GLY A 511
ILE A 510
ILE A 354
ILE A 289
None
1.10A 6ebpD-4az7A:
undetectable
6ebpD-4az7A:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmr RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA


(Bacillus cereus)
PF00268
(Ribonuc_red_sm)
7 LEU A  58
THR A  59
ASP A  62
ILE A 103
PHE A 104
ILE A 188
ILE A 191
None
None
FE2  A1323 (-2.4A)
None
None
None
None
0.50A 6ebpD-4bmrA:
38.4
6ebpD-4bmrA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmr RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA


(Bacillus cereus)
PF00268
(Ribonuc_red_sm)
7 LEU A  58
THR A  59
ASP A  62
SER A  99
ILE A 103
ILE A 188
ILE A 191
None
None
FE2  A1323 (-2.4A)
None
None
None
None
0.71A 6ebpD-4bmrA:
38.4
6ebpD-4bmrA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bv4 PROTEIN TOLL,
VARIABLE LYMPHOCYTE
RECEPTOR B CHIMERA


(Drosophila
melanogaster;
Eptatretus
burgeri)
PF11921
(DUF3439)
PF13855
(LRR_8)
5 PHE R 193
LEU R 196
GLY R 218
ILE R 216
ILE R 202
None
1.12A 6ebpD-4bv4R:
undetectable
6ebpD-4bv4R:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cp6 CHOLINE BINDING
PROTEIN PCPA


(Streptococcus
pneumoniae)
PF13306
(LRR_5)
5 PHE A 161
SER A 140
GLY A 139
ILE A 145
ILE A 123
None
1.11A 6ebpD-4cp6A:
undetectable
6ebpD-4cp6A:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7q RALF,
PROLINE/BETAINE
TRANSPORTER


(Legionella
pneumophila;
Rickettsia
prowazekii)
PF01369
(Sec7)
5 THR A 215
ASP A 213
ILE A 316
PHE A 233
ILE A 205
None
1.11A 6ebpD-4d7qA:
undetectable
6ebpD-4d7qA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dr0 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA


(Bacillus
subtilis)
PF00268
(Ribonuc_red_sm)
8 LEU A  62
THR A  63
ASP A  66
SER A 104
ILE A 108
PHE A 109
ILE A 191
ILE A 194
None
None
MN  A 402 (-2.3A)
None
None
None
None
None
0.54A 6ebpD-4dr0A:
38.5
6ebpD-4dr0A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fin ETTA (YJJK) ABCF
FAMILY PROTEIN


(Escherichia
coli)
PF00005
(ABC_tran)
PF12848
(ABC_tran_Xtn)
5 LEU A 365
THR A 364
GLY A 359
ILE A 354
ILE A 497
None
None
SO4  A 603 (-3.3A)
None
None
1.09A 6ebpD-4finA:
undetectable
6ebpD-4finA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fs7 UNCHARACTERIZED
PROTEIN


(Bacteroides
ovatus)
PF13306
(LRR_5)
5 PHE A  87
GLY A 106
ILE A  82
ILE A  96
ILE A 119
None
0.93A 6ebpD-4fs7A:
undetectable
6ebpD-4fs7A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fs7 UNCHARACTERIZED
PROTEIN


(Bacteroides
ovatus)
PF13306
(LRR_5)
5 PHE A 110
GLY A 129
ILE A 105
ILE A 119
ILE A 142
None
1.10A 6ebpD-4fs7A:
undetectable
6ebpD-4fs7A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fs7 UNCHARACTERIZED
PROTEIN


(Bacteroides
ovatus)
PF13306
(LRR_5)
5 PHE A 133
GLY A 152
ILE A 128
ILE A 142
ILE A 164
None
0.94A 6ebpD-4fs7A:
undetectable
6ebpD-4fs7A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fs7 UNCHARACTERIZED
PROTEIN


(Bacteroides
ovatus)
PF13306
(LRR_5)
5 PHE A 336
GLY A 355
ILE A 331
ILE A 345
ILE A 368
None
0.76A 6ebpD-4fs7A:
undetectable
6ebpD-4fs7A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g4s PROTEASOME CHAPERONE
1


(Saccharomyces
cerevisiae)
PF10450
(POC1)
5 PHE O  38
GLY O  72
ILE O 124
ILE O 154
ILE O 150
None
1.06A 6ebpD-4g4sO:
undetectable
6ebpD-4g4sO:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdu AEROTOLERANCE-RELATE
D MEMBRANE PROTEIN


(Bacteroides
fragilis)
PF00092
(VWA)
5 ASP A 129
GLY A 132
ILE A  94
ILE A 283
ILE A 287
None
0.79A 6ebpD-4jduA:
undetectable
6ebpD-4jduA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1e PURINE NUCLEOSIDE
PHOSPHORYLASE


(Planctopirus
limnophila)
PF01048
(PNP_UDP_1)
5 PHE A 231
LEU A 110
ILE A 129
ILE A 269
ILE A 273
None
1.06A 6ebpD-4m1eA:
undetectable
6ebpD-4m1eA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n83 RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA


(Streptococcus
sanguinis)
PF00268
(Ribonuc_red_sm)
9 PHE A  59
LEU A  62
THR A  63
ASP A  66
SER A 103
ILE A 107
PHE A 108
ILE A 184
ILE A 187
None
None
None
MN  A 402 (-2.8A)
None
None
None
None
None
0.52A 6ebpD-4n83A:
38.5
6ebpD-4n83A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qed ELXO

(Staphylococcus
epidermidis)
PF13561
(adh_short_C2)
5 PHE A 147
SER A 140
GLY A 143
ILE A 141
ILE A 185
None
NAP  A 300 ( 3.9A)
None
None
None
1.13A 6ebpD-4qedA:
undetectable
6ebpD-4qedA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru4 TAIL SPIKE PROTEIN
GP49


(Pseudomonas
virus LKA1)
PF13229
(Beta_helix)
5 LEU A 390
GLY A 249
ILE A 250
ILE A 378
ILE A 380
None
1.13A 6ebpD-4ru4A:
undetectable
6ebpD-4ru4A:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x57 UBIQUITIN-CONJUGATIN
G ENZYME E2 8


(Arabidopsis
thaliana)
PF00179
(UQ_con)
5 LEU A 109
GLY A  39
ILE A  37
ILE A  84
ILE A  78
None
1.07A 6ebpD-4x57A:
undetectable
6ebpD-4x57A:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xru HEN1

(Capnocytophaga
gingivalis)
no annotation 5 PHE C  84
LEU C  87
ILE C  79
ILE C   5
ILE C 116
None
1.00A 6ebpD-4xruC:
undetectable
6ebpD-4xruC:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynn PROTEASE DO

(Legionella
pneumophila)
PF13180
(PDZ_2)
PF13365
(Trypsin_2)
5 LEU A  93
THR A  92
ILE A  21
ILE A  68
ILE A  76
None
1.08A 6ebpD-4ynnA:
undetectable
6ebpD-4ynnA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aex AMMONIUM TRANSPORTER
MEP2


(Saccharomyces
cerevisiae)
PF00909
(Ammonium_transp)
5 LEU A  56
GLY A 142
ILE A  49
ILE A 297
ILE A 347
None
1.05A 6ebpD-5aexA:
2.6
6ebpD-5aexA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5djw ALPHA-GLUCOSIDASE II

(Bacteroides
thetaiotaomicron)
PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF17137
(DUF5110)
5 LEU A 164
THR A 165
GLY A 423
ILE A 158
ILE A 149
None
1.10A 6ebpD-5djwA:
undetectable
6ebpD-5djwA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ekp UNCHARACTERIZED
GLYCOSYLTRANSFERASE
SLL0501


(Synechocystis
sp. PCC 6803)
no annotation 5 PHE C  22
LEU C  25
ILE C  63
ILE C   9
ILE C   7
None
1.11A 6ebpD-5ekpC:
undetectable
6ebpD-5ekpC:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f0o COHESIN SUBUNIT
PDS5,
KLTH0D07062P,KLTH0D0
7062P,KLTH0D07062P,C
OHESIN SUBUNIT PDS5,
KLTH0D07062P,KLTH0D0
7062P,KLTH0D07062P,C
OHESIN SUBUNIT PDS5,
KLTH0D07062P,KLTH0D0
7062P,KLTH0D07062P,C
OHESIN SUBUNIT PDS5,
KLTH0D07062P,KLTH0D0
7062P


(Lachancea
thermotolerans)
no annotation 5 PHE A 435
LEU A 438
ILE A 477
ILE A 460
ILE A 484
None
1.12A 6ebpD-5f0oA:
undetectable
6ebpD-5f0oA:
6.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hiu GTPASE
ACTIVATOR-LIKE
PROTEIN


(Chaetomium
thermophilum)
PF11864
(DUF3384)
6 PHE A 207
LEU A 210
THR A 211
GLY A 276
ILE A 274
ILE A 262
PHE  A 207 ( 1.3A)
LEU  A 210 ( 0.5A)
THR  A 211 ( 0.8A)
GLY  A 276 ( 0.0A)
ILE  A 274 ( 0.7A)
ILE  A 262 ( 0.7A)
0.97A 6ebpD-5hiuA:
undetectable
6ebpD-5hiuA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iy7 TRANSCRIPTION
INITIATION FACTOR
IIE SUBUNIT BETA


(Homo sapiens)
PF02186
(TFIIE_beta)
5 LEU R  97
THR R  98
GLY R 135
ILE R 133
ILE R 130
None
1.08A 6ebpD-5iy7R:
undetectable
6ebpD-5iy7R:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szs SPIKE GLYCOPROTEIN

(Human
coronavirus
NL63)
PF01600
(Corona_S1)
PF01601
(Corona_S2)
5 LEU A 151
THR A 159
ILE A 144
ILE A  89
ILE A 105
None
0.97A 6ebpD-5szsA:
undetectable
6ebpD-5szsA:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr3 DIHYDROLIPOYL
DEHYDROGENASE


(Pseudomonas
putida)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
5 PHE A 437
THR A 439
ASP A 443
GLY A 431
ILE A 433
TRS  A 502 ( 4.2A)
None
None
None
None
1.08A 6ebpD-5tr3A:
undetectable
6ebpD-5tr3A:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ucd NAD(P)-DEPENDENT
BENZALDEHYDE
DEHYDROGENASE


(Pseudomonas
putida)
PF00171
(Aldedh)
6 LEU A 127
THR A 128
GLY A 132
ILE A 134
ILE A 159
ILE A 142
None
1.11A 6ebpD-5ucdA:
undetectable
6ebpD-5ucdA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb DNA REPLICATION
LICENSING FACTOR
MCM6


(Saccharomyces
cerevisiae)
PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB)
5 LEU 6 552
SER 6 677
GLY 6 634
ILE 6 635
ILE 6 569
None
1.13A 6ebpD-5udb6:
undetectable
6ebpD-5udb6:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uiw C-C CHEMOKINE
RECEPTOR TYPE
5,RUBREDOXIN CHIMERA


(Clostridium
pasteurianum;
Homo sapiens)
PF00001
(7tm_1)
PF00301
(Rubredoxin)
5 PHE A  78
LEU A  81
THR A  82
GLY A 106
ILE A 110
None
OLC  A1103 ( 4.6A)
None
None
None
1.13A 6ebpD-5uiwA:
2.1
6ebpD-5uiwA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ukw GLUCOSE-6-PHOSPHATE
1-DEHYDROGENASE


(Homo sapiens)
PF00479
(G6PD_N)
PF02781
(G6PD_C)
5 PHE A  34
LEU A 137
GLY A  69
ILE A  36
ILE A 168
None
1.10A 6ebpD-5ukwA:
undetectable
6ebpD-5ukwA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uz5 56 KDA U1 SMALL
NUCLEAR
RIBONUCLEOPROTEIN
COMPONENT


(Saccharomyces
cerevisiae)
no annotation 5 LEU G 117
GLY G  67
ILE G  65
PHE G 224
ILE G  97
None
1.09A 6ebpD-5uz5G:
undetectable
6ebpD-5uz5G:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v3s TWO-COMPONENT
INSECTICIDAL PROTEIN
16 KDA UNIT


(Alcaligenes
faecalis)
PF06355
(Aegerolysin)
5 PHE A  97
LEU A 113
ASP A 111
GLY A  86
ILE A 138
None
0.99A 6ebpD-5v3sA:
undetectable
6ebpD-5v3sA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wln TYPE II SECRETION
SYSTEM PROTEIN D


(Pseudomonas
aeruginosa)
no annotation 5 THR G 309
SER G 268
GLY G 270
ILE G 267
ILE G 292
None
1.14A 6ebpD-5wlnG:
undetectable
6ebpD-5wlnG:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z2g L-AMINO ACID OXIDASE

(Naja atra)
no annotation 5 PHE A 398
LEU A 401
ASP A 402
ILE A 344
ILE A 409
None
0.99A 6ebpD-5z2gA:
undetectable
6ebpD-5z2gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ged PRGB

(Enterococcus
faecalis)
no annotation 5 PHE A 275
THR A 549
ILE A 369
ILE A 418
ILE A 523
None
1.02A 6ebpD-6gedA:
undetectable
6ebpD-6gedA:
20.24