SIMILAR PATTERNS OF AMINO ACIDS FOR 6EBP_D_DAHD123_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ecx | AMINOTRANSFERASE (Thermotogamaritima) |
PF00266(Aminotran_5) | 5 | PHE A 299GLY A 304ILE A 349ILE A 369ILE A 372 | None | 1.06A | 6ebpD-1ecxA:undetectable | 6ebpD-1ecxA:10.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eww | ANTIFREEZE PROTEIN (Choristoneurafumiferana) |
PF05264(CfAFP) | 5 | PHE A 87SER A 52GLY A 54ILE A 82ILE A 64 | None | 1.02A | 6ebpD-1ewwA:undetectable | 6ebpD-1ewwA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8r | L-AMINO ACID OXIDASE (Calloselasmarhodostoma) |
PF01593(Amino_oxidase) | 5 | PHE A 381LEU A 384ASP A 385ILE A 327ILE A 392 | None | 1.04A | 6ebpD-1f8rA:undetectable | 6ebpD-1f8rA:9.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g0d | PROTEIN-GLUTAMINEGAMMA-GLUTAMYLTRANSFERASE (Pagrus major) |
PF00868(Transglut_N)PF00927(Transglut_C)PF01841(Transglut_core) | 5 | PHE A 189LEU A 192ASP A 205GLY A 63ILE A 105 | None | 1.06A | 6ebpD-1g0dA:undetectable | 6ebpD-1g0dA:8.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g71 | DNA PRIMASE (Pyrococcusfuriosus) |
PF01896(DNA_primase_S) | 5 | SER A 73GLY A 38PHE A 39ILE A 24ILE A 28 | None | 1.00A | 6ebpD-1g71A:undetectable | 6ebpD-1g71A:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kgp | RIBONUCLEOTIDEREDUCTASE PROTEINR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 70LEU A 73THR A 74ASP A 77ILE A 118PHE A 119ILE A 195ILE A 198 | NoneNoneNone MN A1001 (-2.7A)NoneNoneNoneNone | 0.43A | 6ebpD-1kgpA:42.2 | 6ebpD-1kgpA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kgp | RIBONUCLEOTIDEREDUCTASE PROTEINR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 70LEU A 73THR A 74ASP A 77SER A 114ILE A 118ILE A 195ILE A 198 | NoneNoneNone MN A1001 (-2.7A)NoneNoneNoneNone | 0.62A | 6ebpD-1kgpA:42.2 | 6ebpD-1kgpA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kru | GALACTOSIDEO-ACETYLTRANSFERASE (Escherichiacoli) |
PF00132(Hexapep)PF12464(Mac)PF14602(Hexapep_2) | 5 | LEU A 88ILE A 51PHE A 36ILE A 78ILE A 76 | None | 1.11A | 6ebpD-1kruA:undetectable | 6ebpD-1kruA:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mqt | POLYPROTEIN CAPSIDPROTEIN (Enterovirus B) |
PF00073(Rhv) | 5 | PHE C 85LEU C 95THR C 88GLY C 188ILE C 114 | None | 1.05A | 6ebpD-1mqtC:undetectable | 6ebpD-1mqtC:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ogq | POLYGALACTURONASEINHIBITING PROTEIN (Phaseolusvulgaris) |
PF08263(LRRNT_2) | 5 | LEU A 141GLY A 170PHE A 194ILE A 154ILE A 145 | None | 1.08A | 6ebpD-1ogqA:undetectable | 6ebpD-1ogqA:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oh9 | ACETYLGLUTAMATEKINASE (Escherichiacoli) |
PF00696(AA_kinase) | 5 | PHE A 24LEU A 23ILE A 97ILE A 40ILE A 7 | None | 1.03A | 6ebpD-1oh9A:undetectable | 6ebpD-1oh9A:11.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pc3 | PHOSPHATE-BINDINGPROTEIN 1 (Mycobacteriumtuberculosis) |
PF12849(PBP_like_2) | 6 | PHE A 312LEU A 309THR A 308ILE A 58PHE A 49ILE A 79 | None | 1.49A | 6ebpD-1pc3A:undetectable | 6ebpD-1pc3A:11.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pm2 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1BETA CHAIN (Escherichiacoli) |
PF00268(Ribonuc_red_sm) | 5 | THR A 81SER A 121ILE A 125ILE A 231ILE A 234 | None | 0.51A | 6ebpD-1pm2A:29.0 | 6ebpD-1pm2A:14.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1r2f | PROTEIN(RIBONUCLEOTIDEREDUCTASE R2) (Salmonellaenterica) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 60LEU A 63THR A 64ASP A 67ILE A 108PHE A 109ILE A 185ILE A 188 | NoneNoneNone FE A 400 (-3.0A)NoneNoneNoneNone | 0.28A | 6ebpD-1r2fA:42.6 | 6ebpD-1r2fA:30.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1r2f | PROTEIN(RIBONUCLEOTIDEREDUCTASE R2) (Salmonellaenterica) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 60LEU A 63THR A 64ASP A 67SER A 104ILE A 108ILE A 185ILE A 188 | NoneNoneNone FE A 400 (-3.0A)NoneNoneNoneNone | 0.57A | 6ebpD-1r2fA:42.6 | 6ebpD-1r2fA:30.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1suh | EPITHELIAL CADHERIN (Mus musculus) |
PF00028(Cadherin) | 5 | LEU A 21GLY A 58ILE A 53ILE A 96ILE A 7 | None | 0.97A | 6ebpD-1suhA:undetectable | 6ebpD-1suhA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1suw | PROBABLE INORGANICPOLYPHOSPHATE/ATP-NAD KINASE (Archaeoglobusfulgidus) |
PF01513(NAD_kinase) | 5 | LEU A 76THR A 77SER A 45GLY A 47ILE A 65 | None | 1.11A | 6ebpD-1suwA:undetectable | 6ebpD-1suwA:12.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdk | L-AMINO ACID OXIDASE (Gloydius halys) |
PF01593(Amino_oxidase) | 5 | PHE A 381LEU A 384ASP A 385ILE A 327ILE A 392 | None | 0.96A | 6ebpD-1tdkA:undetectable | 6ebpD-1tdkA:10.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 9 | PHE A 65LEU A 68THR A 69ASP A 72SER A 109ILE A 113PHE A 114ILE A 190ILE A 193 | NoneNoneNone FE A1292 (-2.5A)NoneNoneNoneNoneNone | 0.45A | 6ebpD-1uzrA:40.9 | 6ebpD-1uzrA:42.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v33 | DNA PRIMASE SMALLSUBUNIT (Pyrococcushorikoshii) |
PF01896(DNA_primase_S) | 5 | SER A 73GLY A 38PHE A 39ILE A 24ILE A 28 | None | 1.00A | 6ebpD-1v33A:undetectable | 6ebpD-1v33A:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vlm | SAM-DEPENDENTMETHYLTRANSFERASE (Thermotogamaritima) |
PF08241(Methyltransf_11) | 5 | LEU A 162GLY A 204ILE A 202PHE A 171ILE A 100 | None | 0.86A | 6ebpD-1vlmA:undetectable | 6ebpD-1vlmA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wvg | CDP-GLUCOSE4,6-DEHYDRATASE (Salmonellaenterica) |
PF16363(GDP_Man_Dehyd) | 5 | THR A 325ILE A 277PHE A 276ILE A 199ILE A 331 | None | 1.12A | 6ebpD-1wvgA:undetectable | 6ebpD-1wvgA:14.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y6l | UBIQUITIN-CONJUGATING ENZYME E2E2 (Homo sapiens) |
PF00179(UQ_con) | 5 | SER A 35GLY A 24ILE A 54ILE A 106ILE A 37 | None | 1.10A | 6ebpD-1y6lA:undetectable | 6ebpD-1y6lA:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a6o | ISHP608 TRANSPOSASE (Helicobacterpylori) |
PF01797(Y1_Tnp) | 6 | PHE A 80GLY A 76ILE A 71PHE A 75ILE A 21ILE A 113 | None | 1.18A | 6ebpD-2a6oA:undetectable | 6ebpD-2a6oA:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bx6 | XRP2 PROTEIN (Homo sapiens) |
PF07986(TBCC) | 5 | PHE A 62GLY A 94ILE A 74ILE A 64ILE A 83 | None | 1.12A | 6ebpD-2bx6A:undetectable | 6ebpD-2bx6A:12.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fsv | NAD(P)TRANSHYDROGENASESUBUNIT BETA (Rhodospirillumrubrum) |
PF02233(PNTB) | 5 | PHE C 126LEU C 161GLY C 129ILE C 128ILE C 198 | NoneNoneNAP C 700 (-3.8A)NoneNone | 1.09A | 6ebpD-2fsvC:undetectable | 6ebpD-2fsvC:15.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g0t | CONSERVEDHYPOTHETICAL PROTEIN (Thermotogamaritima) |
PF07755(DUF1611)PF17396(DUF1611_N) | 5 | LEU A 38GLY A 198ILE A 199ILE A 111ILE A 82 | None | 0.99A | 6ebpD-2g0tA:undetectable | 6ebpD-2g0tA:13.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gb4 | THIOPURINES-METHYLTRANSFERASE (Mus musculus) |
PF05724(TPMT) | 5 | PHE A 61GLY A 139ILE A 138ILE A 130ILE A 164 | NoneNoneNoneSAH A 300 (-4.5A)None | 1.07A | 6ebpD-2gb4A:undetectable | 6ebpD-2gb4A:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hnh | DNA POLYMERASE IIIALPHA SUBUNIT (Escherichiacoli) |
PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 5 | LEU A 879GLY A 840ILE A 838ILE A 816ILE A 849 | None | 1.10A | 6ebpD-2hnhA:undetectable | 6ebpD-2hnhA:5.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iue | INTEGRIN BETA-2-LIKEPROTEIN (Mus musculus) |
PF00362(Integrin_beta) | 5 | LEU A 26ASP A 29ILE A 43PHE A 66ILE A 205 | None | 1.13A | 6ebpD-2iueA:undetectable | 6ebpD-2iueA:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jdx | PROTEIN(L-ARGININE:GLYCINEAMIDINOTRANSFERASE) (Homo sapiens) |
no annotation | 5 | PHE A 383GLY A 387ILE A 388ILE A 311ILE A 315 | None | 1.08A | 6ebpD-2jdxA:undetectable | 6ebpD-2jdxA:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r77 | PHOSPHATIDYLETHANOLAMINE-BINDINGPROTEIN, PUTATIVE (Plasmodiumfalciparum) |
PF01161(PBP) | 5 | PHE A 76GLY A 198ILE A 151ILE A 74ILE A 48 | None | 1.12A | 6ebpD-2r77A:undetectable | 6ebpD-2r77A:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v73 | PUTATIVEEXO-ALPHA-SIALIDASE (Clostridiumperfringens) |
PF02973(Sialidase) | 5 | LEU A 57GLY A 147ILE A 146ILE A 169ILE A 40 | None | 1.04A | 6ebpD-2v73A:undetectable | 6ebpD-2v73A:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w0m | SSO2452 (Sulfolobussolfataricus) |
PF06745(ATPase) | 5 | LEU A 15GLY A 8ILE A 9ILE A 202ILE A 187 | None | 1.13A | 6ebpD-2w0mA:undetectable | 6ebpD-2w0mA:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahx | BETA-GLUCOSIDASE A (Clostridiumcellulovorans) |
PF00232(Glyco_hydro_1) | 5 | PHE A 151GLY A 215ILE A 217ILE A 119ILE A 117 | None | 1.07A | 6ebpD-3ahxA:undetectable | 6ebpD-3ahxA:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bzh | UBIQUITIN-CONJUGATING ENZYME E2 E1 (Homo sapiens) |
PF00179(UQ_con) | 5 | LEU A 155GLY A 85ILE A 83ILE A 130ILE A 124 | NoneNoneNoneGOL A 200 (-3.7A)None | 1.09A | 6ebpD-3bzhA:undetectable | 6ebpD-3bzhA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bzh | UBIQUITIN-CONJUGATING ENZYME E2 E1 (Homo sapiens) |
PF00179(UQ_con) | 5 | SER A 81GLY A 70ILE A 100ILE A 152ILE A 83 | None | 1.11A | 6ebpD-3bzhA:undetectable | 6ebpD-3bzhA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d6j | PUTATIVE HALOACIDDEHALOGENASE-LIKEHYDROLASE (Bacteroidesfragilis) |
PF13419(HAD_2) | 5 | THR A 13SER A 109ILE A 108ILE A 132ILE A 116 | NonePO4 A 251 (-2.6A)NoneNoneNone | 1.09A | 6ebpD-3d6jA:undetectable | 6ebpD-3d6jA:14.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e74 | ALLANTOINASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 5 | PHE A 388GLY A 10ILE A 7ILE A 30ILE A 33 | None | 1.06A | 6ebpD-3e74A:undetectable | 6ebpD-3e74A:9.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9k | KYNURENINASE (Homo sapiens) |
PF00266(Aminotran_5) | 5 | LEU A 368THR A 365GLY A 400ILE A 405ILE A 390 | None | 0.96A | 6ebpD-3e9kA:undetectable | 6ebpD-3e9kA:10.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgx | RBSTP2171 (Geobacillusstearothermophilus) |
no annotation | 5 | LEU A 91THR A 92ILE A 73PHE A 70ILE A 23 | None | 0.93A | 6ebpD-3fgxA:undetectable | 6ebpD-3fgxA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETA (Moorellathermoacetica) |
PF03063(Prismane) | 5 | PHE A 174LEU A 171GLY A 207ILE A 208ILE A 247 | None | 0.99A | 6ebpD-3i04A:undetectable | 6ebpD-3i04A:7.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ial | PROLYL-TRNASYNTHETASE (Giardiaintestinalis) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon)PF09180(ProRS-C_1) | 5 | LEU A 356THR A 355ILE A 419ILE A 390ILE A 328 | None | 1.10A | 6ebpD-3ialA:undetectable | 6ebpD-3ialA:9.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kg7 | CURH (Lyngbyamajuscula) |
PF14765(PS-DH) | 5 | LEU A1166THR A1165ILE A1195ILE A1135ILE A 985 | None | 1.00A | 6ebpD-3kg7A:undetectable | 6ebpD-3kg7A:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kxi | GTP-BINDING PROTEIN(HFLX) (Sulfolobussolfataricus) |
PF01926(MMR_HSR1)PF13167(GTP-bdg_N)PF16360(GTP-bdg_M) | 5 | LEU A 252THR A 251ILE A 93ILE A 237ILE A 240 | None | 1.12A | 6ebpD-3kxiA:undetectable | 6ebpD-3kxiA:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk6 | LIPOPROTEIN YBBD (Bacillussubtilis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 5 | PHE A 604THR A 471GLY A 599ILE A 603ILE A 455 | None | 1.08A | 6ebpD-3lk6A:undetectable | 6ebpD-3lk6A:8.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk6 | LIPOPROTEIN YBBD (Bacillussubtilis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 5 | PHE A 604THR A 471GLY A 599ILE A 603ILE A 457 | None | 0.87A | 6ebpD-3lk6A:undetectable | 6ebpD-3lk6A:8.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lkb | PROBABLEBRANCHED-CHAIN AMINOACID ABCTRANSPORTER, AMINOACID BINDING PROTEIN (Thermusthermophilus) |
PF13458(Peripla_BP_6) | 5 | PHE A 67THR A 63SER A 81PHE A 11ILE A 94 | None | 1.09A | 6ebpD-3lkbA:undetectable | 6ebpD-3lkbA:11.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3me5 | CYTOSINE-SPECIFICMETHYLTRANSFERASE (Shigellaflexneri) |
PF00145(DNA_methylase) | 5 | PHE A 103SER A 105GLY A 107ILE A 106PHE A 87 | None | 1.10A | 6ebpD-3me5A:undetectable | 6ebpD-3me5A:10.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 7 | PHE A 70LEU A 73THR A 74ASP A 77ILE A 118ILE A 195ILE A 198 | NoneNoneNoneMN3 A1001 (-2.2A)NoneNoneNone | 0.56A | 6ebpD-3mjoA:40.8 | 6ebpD-3mjoA:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 7 | PHE A 70LEU A 73THR A 74ILE A 118PHE A 119ILE A 195ILE A 198 | None | 0.37A | 6ebpD-3mjoA:40.8 | 6ebpD-3mjoA:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 7 | PHE A 70LEU A 73THR A 74SER A 114ILE A 118ILE A 195ILE A 198 | None | 0.60A | 6ebpD-3mjoA:40.8 | 6ebpD-3mjoA:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n00 | REV-ERBA-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 545THR A 541ILE A 299PHE A 300ILE A 457 | None | 1.08A | 6ebpD-3n00A:undetectable | 6ebpD-3n00A:15.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n3b | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2SUBUNIT BETA (Escherichiacoli) |
no annotation | 7 | PHE B 60LEU B 63ASP B 67SER B 104ILE B 108ILE B 185ILE B 188 | NoneNone MN B 320 (-2.8A)NoneNoneNoneNone | 0.70A | 6ebpD-3n3bB:41.7 | 6ebpD-3n3bB:30.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n3b | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2SUBUNIT BETA (Escherichiacoli) |
no annotation | 8 | PHE B 60LEU B 63THR B 64ASP B 67ILE B 108PHE B 109ILE B 185ILE B 188 | NoneNoneNone MN B 320 (-2.8A)NoneNoneNoneNone | 0.45A | 6ebpD-3n3bB:41.7 | 6ebpD-3n3bB:30.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nas | BETA-PHOSPHOGLUCOMUTASE (Bacillussubtilis) |
PF13419(HAD_2) | 5 | LEU A 8ASP A 7GLY A 111ILE A 135PHE A 132 | None | 1.13A | 6ebpD-3nasA:undetectable | 6ebpD-3nasA:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nd0 | SLL0855 PROTEIN (Synechocystissp. PCC 6803) |
PF00654(Voltage_CLC) | 5 | THR A 399GLY A 196ILE A 195ILE A 148ILE A 105 | None | 1.13A | 6ebpD-3nd0A:undetectable | 6ebpD-3nd0A:8.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3njx | RHAMNOGALACTURONASEB (Aspergillusaculeatus) |
PF09284(RhgB_N)PF14683(CBM-like)PF14686(fn3_3) | 5 | LEU A 506GLY A 420ILE A 419ILE A 481ILE A 403 | None | 1.00A | 6ebpD-3njxA:undetectable | 6ebpD-3njxA:9.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojl | CAP5O (Staphylococcusaureus) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | LEU A 221THR A 222GLY A 251ILE A 215ILE A 236 | None | 1.11A | 6ebpD-3ojlA:undetectable | 6ebpD-3ojlA:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojl | CAP5O (Staphylococcusaureus) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | LEU A 221THR A 222GLY A 251ILE A 247ILE A 236 | None | 0.98A | 6ebpD-3ojlA:undetectable | 6ebpD-3ojlA:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sun | DNA POLYMERASE (Escherichiavirus RB69) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | PHE A 841GLY A 807ILE A 846ILE A 858ILE A 815 | None | 1.07A | 6ebpD-3sunA:undetectable | 6ebpD-3sunA:6.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsw | TIGHT JUNCTIONPROTEIN ZO-1 (Homo sapiens) |
PF00595(PDZ)PF00625(Guanylate_kin)PF07653(SH3_2) | 5 | LEU A 549THR A 548ASP A 547GLY A 440ILE A 445 | None | 1.13A | 6ebpD-3tswA:undetectable | 6ebpD-3tswA:11.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4az7 | BETA-N-ACETYLHEXOSAMINIDASE (Streptococcuspneumoniae) |
PF00728(Glyco_hydro_20) | 5 | THR A 217GLY A 511ILE A 510ILE A 354ILE A 289 | None | 1.10A | 6ebpD-4az7A:undetectable | 6ebpD-4az7A:9.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmr | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillus cereus) |
PF00268(Ribonuc_red_sm) | 7 | LEU A 58THR A 59ASP A 62ILE A 103PHE A 104ILE A 188ILE A 191 | NoneNoneFE2 A1323 (-2.4A)NoneNoneNoneNone | 0.50A | 6ebpD-4bmrA:38.4 | 6ebpD-4bmrA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmr | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillus cereus) |
PF00268(Ribonuc_red_sm) | 7 | LEU A 58THR A 59ASP A 62SER A 99ILE A 103ILE A 188ILE A 191 | NoneNoneFE2 A1323 (-2.4A)NoneNoneNoneNone | 0.71A | 6ebpD-4bmrA:38.4 | 6ebpD-4bmrA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bv4 | PROTEIN TOLL,VARIABLE LYMPHOCYTERECEPTOR B CHIMERA (Drosophilamelanogaster;Eptatretusburgeri) |
PF11921(DUF3439)PF13855(LRR_8) | 5 | PHE R 193LEU R 196GLY R 218ILE R 216ILE R 202 | None | 1.12A | 6ebpD-4bv4R:undetectable | 6ebpD-4bv4R:12.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cp6 | CHOLINE BINDINGPROTEIN PCPA (Streptococcuspneumoniae) |
PF13306(LRR_5) | 5 | PHE A 161SER A 140GLY A 139ILE A 145ILE A 123 | None | 1.11A | 6ebpD-4cp6A:undetectable | 6ebpD-4cp6A:12.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d7q | RALF,PROLINE/BETAINETRANSPORTER (Legionellapneumophila;Rickettsiaprowazekii) |
PF01369(Sec7) | 5 | THR A 215ASP A 213ILE A 316PHE A 233ILE A 205 | None | 1.11A | 6ebpD-4d7qA:undetectable | 6ebpD-4d7qA:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dr0 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillussubtilis) |
PF00268(Ribonuc_red_sm) | 8 | LEU A 62THR A 63ASP A 66SER A 104ILE A 108PHE A 109ILE A 191ILE A 194 | NoneNone MN A 402 (-2.3A)NoneNoneNoneNoneNone | 0.54A | 6ebpD-4dr0A:38.5 | 6ebpD-4dr0A:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fin | ETTA (YJJK) ABCFFAMILY PROTEIN (Escherichiacoli) |
PF00005(ABC_tran)PF12848(ABC_tran_Xtn) | 5 | LEU A 365THR A 364GLY A 359ILE A 354ILE A 497 | NoneNoneSO4 A 603 (-3.3A)NoneNone | 1.09A | 6ebpD-4finA:undetectable | 6ebpD-4finA:10.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 87GLY A 106ILE A 82ILE A 96ILE A 119 | None | 0.93A | 6ebpD-4fs7A:undetectable | 6ebpD-4fs7A:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 110GLY A 129ILE A 105ILE A 119ILE A 142 | None | 1.10A | 6ebpD-4fs7A:undetectable | 6ebpD-4fs7A:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 133GLY A 152ILE A 128ILE A 142ILE A 164 | None | 0.94A | 6ebpD-4fs7A:undetectable | 6ebpD-4fs7A:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 336GLY A 355ILE A 331ILE A 345ILE A 368 | None | 0.76A | 6ebpD-4fs7A:undetectable | 6ebpD-4fs7A:12.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g4s | PROTEASOME CHAPERONE1 (Saccharomycescerevisiae) |
PF10450(POC1) | 5 | PHE O 38GLY O 72ILE O 124ILE O 154ILE O 150 | None | 1.06A | 6ebpD-4g4sO:undetectable | 6ebpD-4g4sO:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdu | AEROTOLERANCE-RELATED MEMBRANE PROTEIN (Bacteroidesfragilis) |
PF00092(VWA) | 5 | ASP A 129GLY A 132ILE A 94ILE A 283ILE A 287 | None | 0.79A | 6ebpD-4jduA:undetectable | 6ebpD-4jduA:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m1e | PURINE NUCLEOSIDEPHOSPHORYLASE (Planctopiruslimnophila) |
PF01048(PNP_UDP_1) | 5 | PHE A 231LEU A 110ILE A 129ILE A 269ILE A 273 | None | 1.06A | 6ebpD-4m1eA:undetectable | 6ebpD-4m1eA:14.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n83 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Streptococcussanguinis) |
PF00268(Ribonuc_red_sm) | 9 | PHE A 59LEU A 62THR A 63ASP A 66SER A 103ILE A 107PHE A 108ILE A 184ILE A 187 | NoneNoneNone MN A 402 (-2.8A)NoneNoneNoneNoneNone | 0.52A | 6ebpD-4n83A:38.5 | 6ebpD-4n83A:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qed | ELXO (Staphylococcusepidermidis) |
PF13561(adh_short_C2) | 5 | PHE A 147SER A 140GLY A 143ILE A 141ILE A 185 | NoneNAP A 300 ( 3.9A)NoneNoneNone | 1.13A | 6ebpD-4qedA:undetectable | 6ebpD-4qedA:12.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ru4 | TAIL SPIKE PROTEINGP49 (Pseudomonasvirus LKA1) |
PF13229(Beta_helix) | 5 | LEU A 390GLY A 249ILE A 250ILE A 378ILE A 380 | None | 1.13A | 6ebpD-4ru4A:undetectable | 6ebpD-4ru4A:10.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x57 | UBIQUITIN-CONJUGATING ENZYME E2 8 (Arabidopsisthaliana) |
PF00179(UQ_con) | 5 | LEU A 109GLY A 39ILE A 37ILE A 84ILE A 78 | None | 1.07A | 6ebpD-4x57A:undetectable | 6ebpD-4x57A:27.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xru | HEN1 (Capnocytophagagingivalis) |
no annotation | 5 | PHE C 84LEU C 87ILE C 79ILE C 5ILE C 116 | None | 1.00A | 6ebpD-4xruC:undetectable | 6ebpD-4xruC:11.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ynn | PROTEASE DO (Legionellapneumophila) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | LEU A 93THR A 92ILE A 21ILE A 68ILE A 76 | None | 1.08A | 6ebpD-4ynnA:undetectable | 6ebpD-4ynnA:10.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aex | AMMONIUM TRANSPORTERMEP2 (Saccharomycescerevisiae) |
PF00909(Ammonium_transp) | 5 | LEU A 56GLY A 142ILE A 49ILE A 297ILE A 347 | None | 1.05A | 6ebpD-5aexA:2.6 | 6ebpD-5aexA:9.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5djw | ALPHA-GLUCOSIDASE II (Bacteroidesthetaiotaomicron) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF17137(DUF5110) | 5 | LEU A 164THR A 165GLY A 423ILE A 158ILE A 149 | None | 1.10A | 6ebpD-5djwA:undetectable | 6ebpD-5djwA:7.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ekp | UNCHARACTERIZEDGLYCOSYLTRANSFERASESLL0501 (Synechocystissp. PCC 6803) |
no annotation | 5 | PHE C 22LEU C 25ILE C 63ILE C 9ILE C 7 | None | 1.11A | 6ebpD-5ekpC:undetectable | 6ebpD-5ekpC:12.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f0o | COHESIN SUBUNITPDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P (Lachanceathermotolerans) |
no annotation | 5 | PHE A 435LEU A 438ILE A 477ILE A 460ILE A 484 | None | 1.12A | 6ebpD-5f0oA:undetectable | 6ebpD-5f0oA:6.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hiu | GTPASEACTIVATOR-LIKEPROTEIN (Chaetomiumthermophilum) |
PF11864(DUF3384) | 6 | PHE A 207LEU A 210THR A 211GLY A 276ILE A 274ILE A 262 | PHE A 207 ( 1.3A)LEU A 210 ( 0.5A)THR A 211 ( 0.8A)GLY A 276 ( 0.0A)ILE A 274 ( 0.7A)ILE A 262 ( 0.7A) | 0.97A | 6ebpD-5hiuA:undetectable | 6ebpD-5hiuA:9.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iy7 | TRANSCRIPTIONINITIATION FACTORIIE SUBUNIT BETA (Homo sapiens) |
PF02186(TFIIE_beta) | 5 | LEU R 97THR R 98GLY R 135ILE R 133ILE R 130 | None | 1.08A | 6ebpD-5iy7R:undetectable | 6ebpD-5iy7R:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5szs | SPIKE GLYCOPROTEIN (HumancoronavirusNL63) |
PF01600(Corona_S1)PF01601(Corona_S2) | 5 | LEU A 151THR A 159ILE A 144ILE A 89ILE A 105 | None | 0.97A | 6ebpD-5szsA:undetectable | 6ebpD-5szsA:4.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr3 | DIHYDROLIPOYLDEHYDROGENASE (Pseudomonasputida) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | PHE A 437THR A 439ASP A 443GLY A 431ILE A 433 | TRS A 502 ( 4.2A)NoneNoneNoneNone | 1.08A | 6ebpD-5tr3A:undetectable | 6ebpD-5tr3A:9.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ucd | NAD(P)-DEPENDENTBENZALDEHYDEDEHYDROGENASE (Pseudomonasputida) |
PF00171(Aldedh) | 6 | LEU A 127THR A 128GLY A 132ILE A 134ILE A 159ILE A 142 | None | 1.11A | 6ebpD-5ucdA:undetectable | 6ebpD-5ucdA:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5udb | DNA REPLICATIONLICENSING FACTORMCM6 (Saccharomycescerevisiae) |
PF00493(MCM)PF14551(MCM_N)PF17207(MCM_OB) | 5 | LEU 6 552SER 6 677GLY 6 634ILE 6 635ILE 6 569 | None | 1.13A | 6ebpD-5udb6:undetectable | 6ebpD-5udb6:5.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uiw | C-C CHEMOKINERECEPTOR TYPE5,RUBREDOXIN CHIMERA (Clostridiumpasteurianum;Homo sapiens) |
PF00001(7tm_1)PF00301(Rubredoxin) | 5 | PHE A 78LEU A 81THR A 82GLY A 106ILE A 110 | NoneOLC A1103 ( 4.6A)NoneNoneNone | 1.13A | 6ebpD-5uiwA:2.1 | 6ebpD-5uiwA:11.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ukw | GLUCOSE-6-PHOSPHATE1-DEHYDROGENASE (Homo sapiens) |
PF00479(G6PD_N)PF02781(G6PD_C) | 5 | PHE A 34LEU A 137GLY A 69ILE A 36ILE A 168 | None | 1.10A | 6ebpD-5ukwA:undetectable | 6ebpD-5ukwA:11.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uz5 | 56 KDA U1 SMALLNUCLEARRIBONUCLEOPROTEINCOMPONENT (Saccharomycescerevisiae) |
no annotation | 5 | LEU G 117GLY G 67ILE G 65PHE G 224ILE G 97 | None | 1.09A | 6ebpD-5uz5G:undetectable | 6ebpD-5uz5G:10.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v3s | TWO-COMPONENTINSECTICIDAL PROTEIN16 KDA UNIT (Alcaligenesfaecalis) |
PF06355(Aegerolysin) | 5 | PHE A 97LEU A 113ASP A 111GLY A 86ILE A 138 | None | 0.99A | 6ebpD-5v3sA:undetectable | 6ebpD-5v3sA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wln | TYPE II SECRETIONSYSTEM PROTEIN D (Pseudomonasaeruginosa) |
no annotation | 5 | THR G 309SER G 268GLY G 270ILE G 267ILE G 292 | None | 1.14A | 6ebpD-5wlnG:undetectable | 6ebpD-5wlnG:7.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z2g | L-AMINO ACID OXIDASE (Naja atra) |
no annotation | 5 | PHE A 398LEU A 401ASP A 402ILE A 344ILE A 409 | None | 0.99A | 6ebpD-5z2gA:undetectable | 6ebpD-5z2gA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ged | PRGB (Enterococcusfaecalis) |
no annotation | 5 | PHE A 275THR A 549ILE A 369ILE A 418ILE A 523 | None | 1.02A | 6ebpD-6gedA:undetectable | 6ebpD-6gedA:20.24 |