SIMILAR PATTERNS OF AMINO ACIDS FOR 6E43_D_BEZD502

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c72 PROTEIN (GLUTATHIONE
S-TRANSFERASE)

(Gallus gallus) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 PHE A 147
VAL A 162
LEU A 134
LEU A 137
 None
 1.00A 6e43D-1c72A:
2.0		 6e43D-1c72A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1csy SYK PROTEIN TYROSINE
KINASE

(Homo sapiens) 		PF00017
(SH2) 		4 PHE A  16
LEU A  73
LEU A  84
HIS A  10
 None
 0.92A 6e43D-1csyA:
0.0		 6e43D-1csyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1de3 RIBONUCLEASE
ALPHA-SARCIN

(Aspergillus
giganteus) 		no annotation 4 VAL A 122
LEU A  94
LEU A  95
HIS A  50
 None
 0.97A 6e43D-1de3A:
0.0		 6e43D-1de3A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dov ALPHA-CATENIN

(Mus musculus) 		PF01044
(Vinculin) 		4 VAL A  91
LEU A 141
LEU A 138
ARG A 137
 None
 0.97A 6e43D-1dovA:
1.4		 6e43D-1dovA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fiu TYPE II RESTRICTION
ENZYME NGOMI

(Neisseria
gonorrhoeae) 		PF09015
(NgoMIV_restric) 		4 LEU A 170
LEU A 179
ARG A 145
HIS A 181
 None
 0.91A 6e43D-1fiuA:
0.0		 6e43D-1fiuA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1irz ARR10-B

(Arabidopsis
thaliana) 		PF00249
(Myb_DNA-binding) 		4 VAL A  49
LEU A   9
LEU A  14
HIS A  15
 None
 0.91A 6e43D-1irzA:
0.6		 6e43D-1irzA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k2p TYROSINE-PROTEIN
KINASE BTK

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LEU A 483
LEU A 486
ARG A 487
HIS A 491
 None
 0.99A 6e43D-1k2pA:
0.0		 6e43D-1k2pA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kw2 VITAMIN D-BINDING
PROTEIN

(Homo sapiens) 		PF00273
(Serum_albumin)
PF09164
(VitD-bind_III) 		4 PHE A 385
VAL A 342
LEU A 369
LEU A 372
 None
 0.92A 6e43D-1kw2A:
0.0		 6e43D-1kw2A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m2w MANNITOL
DEHYDROGENASE

(Pseudomonas
fluorescens) 		PF01232
(Mannitol_dh)
PF08125
(Mannitol_dh_C) 		4 PHE A 184
VAL A 165
LEU A 115
LEU A 119
 None
 0.99A 6e43D-1m2wA:
0.0		 6e43D-1m2wA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qas PHOSPHOLIPASE C
DELTA-1

(Rattus
norvegicus) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		4 VAL A 369
LEU A 409
LEU A 405
HIS A 404
 None
 0.98A 6e43D-1qasA:
undetectable		 6e43D-1qasA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974

(Vibrio cholerae) 		PF12697
(Abhydrolase_6) 		4 PHE A 221
LEU A  92
ARG A  95
HIS A 120
 None
 0.91A 6e43D-1r3dA:
undetectable		 6e43D-1r3dA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s9i DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 PHE A 345
VAL A 177
LEU A 360
LEU A 363
 None
 0.64A 6e43D-1s9iA:
undetectable		 6e43D-1s9iA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sa3 TYPE II RESTRICTION
ENZYME MSPI

(Moraxella sp.) 		PF09208
(Endonuc-MspI) 		4 PHE A 163
LEU A 147
LEU A 150
HIS A 154
 None
 1.00A 6e43D-1sa3A:
undetectable		 6e43D-1sa3A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdj BIOSYNTHETIC
THREONINE DEAMINASE

(Escherichia
coli) 		PF00291
(PALP)
PF00585
(Thr_dehydrat_C) 		4 PHE A 355
VAL A 383
LEU A 396
LEU A 399
 None
 0.95A 6e43D-1tdjA:
undetectable		 6e43D-1tdjA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9s URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Thermus
thermophilus) 		PF14681
(UPRTase) 		4 PHE A  28
LEU A  15
LEU A  18
ARG A  19
 None
 0.86A 6e43D-1v9sA:
undetectable		 6e43D-1v9sA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xtt PROBABLE URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Sulfolobus
solfataricus) 		PF14681
(UPRTase) 		4 PHE A  28
LEU A  15
LEU A  18
ARG A  19
 None
 0.94A 6e43D-1xttA:
undetectable		 6e43D-1xttA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ywg GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Plasmodium
falciparum) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 PHE O  11
VAL O  74
LEU O  40
LEU O  43
 None
 1.02A 6e43D-1ywgO:
undetectable		 6e43D-1ywgO:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csd TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 VAL A 232
LEU A 154
LEU A 146
ARG A 151
 None
 0.91A 6e43D-2csdA:
undetectable		 6e43D-2csdA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cya TYROSYL-TRNA
SYNTHETASE

(Aeropyrum
pernix) 		PF00579
(tRNA-synt_1b) 		4 PHE A 285
VAL A 330
LEU A 321
LEU A 312
 None
 1.00A 6e43D-2cyaA:
undetectable		 6e43D-2cyaA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cyc TYROSYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00579
(tRNA-synt_1b) 		4 PHE A 298
VAL A 343
LEU A 334
LEU A 325
 None
 0.91A 6e43D-2cycA:
undetectable		 6e43D-2cycA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY

(Corynebacterium
glutamicum) 		PF00392
(GntR)
PF07729
(FCD) 		4 VAL A 150
LEU A 203
LEU A 200
HIS A 196
 None
None
None
ZN  A1002 (-3.3A)
 0.57A 6e43D-2di3A:
undetectable		 6e43D-2di3A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6h MYOSIN-2

(Saccharomyces
cerevisiae) 		PF01843
(DIL) 		4 PHE X 231
VAL X 253
LEU X 180
LEU X 183
 None
 0.99A 6e43D-2f6hX:
3.6		 6e43D-2f6hX:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iht CARBOXYETHYLARGININE
SYNTHASE

(Streptomyces
clavuligerus) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 PHE A 458
LEU A 540
LEU A 543
ARG A 544
 None
 0.94A 6e43D-2ihtA:
undetectable		 6e43D-2ihtA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iqc FANCONI ANEMIA GROUP
F PROTEIN

(Homo sapiens) 		PF11107
(FANCF) 		4 VAL A 325
LEU A 351
LEU A 354
ARG A 355
 None
 0.85A 6e43D-2iqcA:
undetectable		 6e43D-2iqcA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2irm MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 7
INTERACTING PROTEIN
1

(Anopheles
gambiae) 		PF00481
(PP2C) 		4 PHE A 227
VAL A 261
LEU A 220
LEU A 222
 None
 0.92A 6e43D-2irmA:
undetectable		 6e43D-2irmA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jcs DEOXYNUCLEOSIDE
KINASE

(Drosophila
melanogaster) 		PF01712
(dNK) 		4 VAL A 159
LEU A 177
LEU A 180
HIS A 184
 None
 1.03A 6e43D-2jcsA:
undetectable		 6e43D-2jcsA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jv3 ETS1 PROTO-ONCOGENE

(Mus musculus) 		PF02198
(SAM_PNT) 		4 PHE A 113
VAL A  77
LEU A 132
LEU A 129
 None
 0.83A 6e43D-2jv3A:
undetectable		 6e43D-2jv3A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2owo DNA LIGASE

(Escherichia
coli) 		PF01653
(DNA_ligase_aden)
PF03119
(DNA_ligase_ZBD)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 VAL A 170
LEU A 235
ARG A 242
HIS A 239
 None
 1.00A 6e43D-2owoA:
2.9		 6e43D-2owoA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q66 POLY(A) POLYMERASE

(Saccharomyces
cerevisiae) 		PF01909
(NTP_transf_2)
PF04926
(PAP_RNA-bind)
PF04928
(PAP_central) 		4 PHE A  85
VAL A 165
LEU A 176
LEU A 171
 None
 0.93A 6e43D-2q66A:
undetectable		 6e43D-2q66A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2re3 UNCHARACTERIZED
PROTEIN

(Ruegeria
pomeroyi) 		PF06938
(DUF1285) 		4 PHE A  95
VAL A  63
LEU A  79
LEU A  70
 None
 0.98A 6e43D-2re3A:
undetectable		 6e43D-2re3A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uzx HEPATOCYTE GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG) 		5 PHE B 146
VAL B  72
LEU B 120
LEU B 130
HIS B  58
 None
 1.42A 6e43D-2uzxB:
undetectable		 6e43D-2uzxB:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vc2 INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF13517
(VCBS) 		4 PHE A  70
VAL A 103
LEU A  55
LEU A  68
 None
 1.04A 6e43D-2vc2A:
undetectable		 6e43D-2vc2A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w9x PUTATIVE ACETYL
XYLAN ESTERASE

(Cellvibrio
japonicus) 		PF00657
(Lipase_GDSL) 		4 VAL A 324
LEU A 345
LEU A 348
HIS A 352
 None
 0.99A 6e43D-2w9xA:
undetectable		 6e43D-2w9xA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbe BIPOLAR KINESIN
KRP-130

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		4 PHE C  54
LEU C 332
LEU C 335
HIS C 339
 None
 1.03A 6e43D-2wbeC:
undetectable		 6e43D-2wbeC:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zcn BIOFILM OPERON
ICAABCD HTH-TYPE
NEGATIVE
TRANSCRIPTIONAL
REGULATOR ICAR

(Staphylococcus
epidermidis) 		PF00440
(TetR_N) 		4 PHE A 147
VAL A 181
LEU A 135
LEU A 143
 None
 1.04A 6e43D-2zcnA:
1.8		 6e43D-2zcnA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zoa PHOSPHOHYDROLASE

(Klebsiella
aerogenes) 		PF00149
(Metallophos) 		4 PHE A  11
VAL A  31
LEU A  70
LEU A  67
 None
 0.95A 6e43D-2zoaA:
undetectable		 6e43D-2zoaA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c1x HEPATOCYTE GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 VAL A1078
LEU A1098
LEU A1097
HIS A1106
 None
 1.02A 6e43D-3c1xA:
undetectable		 6e43D-3c1xA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcy XYLAN ESTERASE 1

(Thermoanaerobacterium
saccharolyticum) 		PF05448
(AXE1) 		4 VAL A 268
LEU A   8
LEU A  11
ARG A  12
 None
 0.98A 6e43D-3fcyA:
undetectable		 6e43D-3fcyA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gvd SERINE
ACETYLTRANSFERASE

(Yersinia pestis) 		PF00132
(Hexapep)
PF06426
(SATase_N) 		4 VAL A 170
LEU A 111
ARG A 115
HIS A 118
 None
 1.04A 6e43D-3gvdA:
undetectable		 6e43D-3gvdA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0r ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Aquifex
aeolicus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		4 PHE B 329
VAL B 397
LEU B 375
LEU B 372
 None
 0.89A 6e43D-3h0rB:
undetectable		 6e43D-3h0rB:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hn2 2-DEHYDROPANTOATE
2-REDUCTASE

(Geobacter
metallireducens) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 VAL A  26
LEU A  42
LEU A  53
HIS A  55
 None
 0.93A 6e43D-3hn2A:
undetectable		 6e43D-3hn2A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE
FAD-SUBUNIT

(Eubacterium
barkeri) 		PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C) 		4 PHE C 230
VAL C 278
LEU C 251
LEU C 254
 None
 1.02A 6e43D-3hrdC:
undetectable		 6e43D-3hrdC:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibg ATPASE, SUBUNIT OF
THE GET COMPLEX

(Aspergillus
fumigatus) 		PF02374
(ArsA_ATPase) 		4 PHE A 328
VAL A 241
LEU A  17
LEU A 332
 ADP  A 349 (-4.5A)
None
None
None
 0.91A 6e43D-3ibgA:
undetectable		 6e43D-3ibgA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3io3 DEHA2D07832P

(Debaryomyces
hansenii) 		PF02374
(ArsA_ATPase) 		4 PHE A 325
VAL A 237
LEU A   9
LEU A 329
 ADP  A 590 (-4.6A)
None
None
None
 0.91A 6e43D-3io3A:
undetectable		 6e43D-3io3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF08938
(HBS1_N) 		4 PHE 1 401
VAL 1 474
LEU 1 478
LEU 1 436
 None
 1.01A 6e43D-3izq1:
undetectable		 6e43D-3izq1:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jxf RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE ZETA

(Homo sapiens) 		PF00194
(Carb_anhydrase) 		4 PHE A 249
VAL A 112
LEU A 218
LEU A 221
 None
 0.98A 6e43D-3jxfA:
undetectable		 6e43D-3jxfA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8i 30KLP

(Treponema
pallidum) 		no annotation 4 PHE A 197
VAL A 276
LEU A 202
LEU A 201
 None
 1.01A 6e43D-3k8iA:
undetectable		 6e43D-3k8iA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd9 COENZYME A DISULFIDE
REDUCTASE

(Pyrococcus
horikoshii) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 PHE A 330
VAL A 174
LEU A 206
LEU A 200
HIS A 203
 None
 1.42A 6e43D-3kd9A:
undetectable		 6e43D-3kd9A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7d TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24) 		4 VAL A 232
LEU A 154
LEU A 146
ARG A 151
 None
 0.97A 6e43D-3m7dA:
undetectable		 6e43D-3m7dA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7g TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13404
(HTH_AsnC-type) 		4 VAL A 232
LEU A 154
LEU A 146
ARG A 151
 None
 0.98A 6e43D-3m7gA:
undetectable		 6e43D-3m7gA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mgx PUTATIVE P450
MONOOXYGENASE

(Amycolatopsis
balhimycina) 		PF00067
(p450) 		4 VAL A 193
LEU A 164
LEU A 167
HIS A 188
 None
 0.98A 6e43D-3mgxA:
undetectable		 6e43D-3mgxA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rri GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Alicyclobacillus
acidocaldarius) 		PF00903
(Glyoxalase) 		4 PHE A  72
LEU A  84
LEU A  81
HIS A  77
 None
 0.95A 6e43D-3rriA:
undetectable		 6e43D-3rriA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vkg DYNEIN HEAVY CHAIN,
CYTOPLASMIC

(Dictyostelium
discoideum) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 PHE A2691
VAL A2657
LEU A2670
LEU A2664
 None
 1.02A 6e43D-3vkgA:
undetectable		 6e43D-3vkgA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wig DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1

(Homo sapiens) 		PF00069
(Pkinase) 		4 PHE A 337
VAL A 174
LEU A 352
LEU A 355
 None
 0.75A 6e43D-3wigA:
undetectable		 6e43D-3wigA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zcw KINESIN-LIKE PROTEIN
KIF11

(Homo sapiens) 		PF00225
(Kinesin) 		4 PHE A  68
LEU A 347
LEU A 350
HIS A 354
 None
 0.79A 6e43D-3zcwA:
undetectable		 6e43D-3zcwA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4be9 STEROL ESTERASE

(Ophiostoma
piceae) 		PF00135
(COesterase) 		4 PHE A 297
LEU A 286
LEU A 289
ARG A 290
 None
 1.01A 6e43D-4be9A:
undetectable		 6e43D-4be9A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bx9 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 33A

(Homo sapiens) 		PF00995
(Sec1) 		4 VAL A 406
LEU A 447
LEU A 444
HIS A 440
 None
 0.99A 6e43D-4bx9A:
undetectable		 6e43D-4bx9A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cxk ARYLSULFATASE

(Pseudomonas
aeruginosa) 		PF00884
(Sulfatase) 		4 PHE A 201
VAL A 298
LEU A 189
LEU A 192
 None
 1.04A 6e43D-4cxkA:
undetectable		 6e43D-4cxkA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fc9 UNCHARACTERIZED
PROTEIN

(Xanthomonas
euvesicatoria) 		no annotation 4 VAL B 595
LEU B 537
LEU B 585
HIS B 584
 None
 1.02A 6e43D-4fc9B:
undetectable		 6e43D-4fc9B:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fnq ALPHA-GALACTOSIDASE
AGAB

(Geobacillus
stearothermophilus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		4 PHE A 343
VAL A 385
LEU A 410
LEU A 365
 None
 0.97A 6e43D-4fnqA:
undetectable		 6e43D-4fnqA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfj TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 VAL A 232
LEU A 154
LEU A 146
ARG A 151
 None
 0.99A 6e43D-4gfjA:
undetectable		 6e43D-4gfjA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4glx DNA LIGASE

(Escherichia
coli) 		PF01653
(DNA_ligase_aden)
PF03119
(DNA_ligase_ZBD)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 VAL A 170
LEU A 235
ARG A 242
HIS A 239
 None
 1.00A 6e43D-4glxA:
2.4		 6e43D-4glxA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gzu FERM, RHOGEF AND
PLECKSTRIN
DOMAIN-CONTAINING
PROTEIN 2

(Mus musculus) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 VAL A 646
LEU A 736
LEU A 733
ARG A 732
 None
 0.98A 6e43D-4gzuA:
1.7		 6e43D-4gzuA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jc8 HOPS COMPONENT VPS33

(Chaetomium
thermophilum) 		PF00995
(Sec1) 		4 VAL A 419
LEU A 460
LEU A 457
HIS A 453
 None
 1.01A 6e43D-4jc8A:
undetectable		 6e43D-4jc8A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus) 		no annotation 4 VAL A  79
LEU A 292
LEU A 296
HIS A   9
 None
 0.98A 6e43D-4lc9A:
undetectable		 6e43D-4lc9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4myd 2-SUCCINYL-6-HYDROXY
-2,4-CYCLOHEXADIENE-
1-CARBOXYLATE
SYNTHASE

(Escherichia
coli) 		PF12697
(Abhydrolase_6) 		4 PHE A 213
LEU A  87
ARG A  90
HIS A 112
 None
164  A 301 (-4.0A)
164  A 301 (-3.6A)
None
 0.95A 6e43D-4mydA:
undetectable		 6e43D-4mydA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0f IGG RECEPTOR FCRN
LARGE SUBUNIT P51

(Homo sapiens) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 PHE A 154
VAL A  26
LEU A  93
LEU A  94
 None
 1.04A 6e43D-4n0fA:
undetectable		 6e43D-4n0fA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nle ADENYLOSUCCINATE
LYASE

(Mycolicibacterium
smegmatis) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 PHE A 122
VAL A 459
LEU A 170
LEU A 173
 None
 0.88A 6e43D-4nleA:
2.6		 6e43D-4nleA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pl2 DUAL-SPECIFICITY RNA
METHYLTRANSFERASE
RLMN

(Escherichia
coli) 		no annotation 4 PHE B 330
LEU B 298
LEU B 295
HIS B 291
 None
 0.89A 6e43D-4pl2B:
undetectable		 6e43D-4pl2B:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s15 NUCLEAR RECEPTOR
ROR-ALPHA

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 PHE A 399
LEU A 477
LEU A 480
HIS A 484
 None
 0.75A 6e43D-4s15A:
1.0		 6e43D-4s15A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ueu TYROSINE KINASE AS -
A COMMON ANCESTOR OF
SRC AND ABL

(synthetic
construct) 		PF07714
(Pkinase_Tyr) 		4 LEU A  90
LEU A  93
ARG A  94
HIS A  99
 None
 0.96A 6e43D-4ueuA:
undetectable		 6e43D-4ueuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzw PUMILIO
DOMAIN-CONTAINING
PROTEIN KIAA0020

(Homo sapiens) 		PF08144
(CPL) 		4 VAL A 502
LEU A 561
LEU A 558
HIS A 555
 None
 1.01A 6e43D-4wzwA:
undetectable		 6e43D-4wzwA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yo5 TSSA

(Escherichia
coli) 		PF16989
(T6SS_VasJ) 		4 PHE A 480
VAL A 525
LEU A 512
LEU A 515
 None
 0.75A 6e43D-4yo5A:
2.4		 6e43D-4yo5A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z5p CYTOCHROME P450
HYDROXYLASE

(Streptomyces
atroolivaceus) 		PF00067
(p450) 		4 VAL A 249
LEU A 262
LEU A 259
HIS A 255
 None
 0.99A 6e43D-4z5pA:
undetectable		 6e43D-4z5pA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5avi OXYSTEROLS RECEPTOR
LXR-ALPHA

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 PHE A 335
LEU A 414
LEU A 417
HIS A 421
 4KM  A 501 (-4.6A)
None
None
4KM  A 501 ( 4.8A)
 0.82A 6e43D-5aviA:
undetectable		 6e43D-5aviA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bmq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN

(Stackebrandtia
nassauensis) 		PF03734
(YkuD) 		4 VAL A 212
LEU A 284
LEU A 256
HIS A 257
 None
 0.87A 6e43D-5bmqA:
undetectable		 6e43D-5bmqA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bxi NUCLEOSIDE
DIPHOSPHATE KINASE

(Toxoplasma
gondii) 		PF00334
(NDK) 		4 VAL A  13
LEU A  93
LEU A 106
ARG A 107
 None
None
None
BCT  A 201 (-4.6A)
 0.82A 6e43D-5bxiA:
undetectable		 6e43D-5bxiA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5clq E3 SUMO-PROTEIN
LIGASE RANBP2

(Homo sapiens) 		PF00638
(Ran_BP1) 		4 LEU B  79
LEU B  68
ARG B  77
HIS B  70
 None
 0.88A 6e43D-5clqB:
undetectable		 6e43D-5clqB:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g06 EXOSOME COMPLEX
COMPONENT RRP40

(Saccharomyces
cerevisiae) 		PF15985
(KH_6) 		4 PHE G 231
VAL G 196
LEU G 175
LEU G 178
 None
 0.86A 6e43D-5g06G:
undetectable		 6e43D-5g06G:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hci GPN-LOOP GTPASE 1

(Saccharomyces
cerevisiae) 		PF03029
(ATP_bind_1) 		4 PHE A  19
VAL A 252
LEU A  27
LEU A  23
 None
 1.02A 6e43D-5hciA:
undetectable		 6e43D-5hciA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hm5 TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 VAL A 232
LEU A 154
LEU A 146
ARG A 151
 None
 0.96A 6e43D-5hm5A:
undetectable		 6e43D-5hm5A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hr6 RLMN METHYLASE

(Escherichia
coli) 		PF04055
(Radical_SAM) 		4 PHE A 330
LEU A 298
LEU A 295
HIS A 291
 None
 0.91A 6e43D-5hr6A:
undetectable		 6e43D-5hr6A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqc LMO1076 PROTEIN

(Listeria
monocytogenes) 		PF13457
(SH3_8) 		4 PHE A 408
VAL A 395
LEU A 352
LEU A 403
 None
 0.88A 6e43D-5jqcA:
undetectable		 6e43D-5jqcA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqw 4-AMINOBUTYRATE
TRANSAMINASE

(Pseudomonas) 		PF00202
(Aminotran_3) 		4 VAL A 444
LEU A 427
LEU A 385
HIS A 370
 None
 1.01A 6e43D-5kqwA:
undetectable		 6e43D-5kqwA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kr6 4-AMINOBUTYRATE
TRANSAMINASE

(Pseudomonas) 		PF00202
(Aminotran_3) 		4 VAL A 444
LEU A 427
LEU A 385
HIS A 370
 None
 1.02A 6e43D-5kr6A:
undetectable		 6e43D-5kr6A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzd N-ACETYLNEURAMINATE
LYASE

(Staphylococcus
aureus) 		PF00701
(DHDPS) 		4 PHE A 276
LEU A 287
LEU A 284
HIS A 280
 None
 0.85A 6e43D-5kzdA:
undetectable		 6e43D-5kzdA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l09 QUORUM-SENSING
TRANSCRIPTIONAL
ACTIVATOR

(Yersinia
enterocolitica) 		PF03472
(Autoind_bind) 		4 VAL A  35
LEU A 151
LEU A 114
HIS A 115
 None
 0.96A 6e43D-5l09A:
undetectable		 6e43D-5l09A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnk MITOCHONDRIAL
COMPLEX I, 39 KDA
SUBUNIT

(Ovis aries) 		no annotation 4 PHE d 172
VAL d 245
LEU d 237
ARG d 235
 None
 0.97A 6e43D-5lnkd:
undetectable		 6e43D-5lnkd:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mio KINESIN-LIKE PROTEIN
KIF2C,KIF2C FUSED TO
A DARPIN,KIF2C FUSED
TO A DARPIN

(Homo sapiens) 		PF00023
(Ank)
PF00225
(Kinesin)
PF12796
(Ank_2) 		4 PHE C 311
LEU C 576
LEU C 579
ARG C 580
 None
 0.95A 6e43D-5mioC:
undetectable		 6e43D-5mioC:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5svd NUCLEOLAR PROTEIN 9

(Saccharomyces
cerevisiae) 		PF00806
(PUF) 		4 LEU A 211
LEU A 208
ARG A 207
HIS A 204
 LEU  A 211 ( 0.6A)
LEU  A 208 ( 0.5A)
ARG  A 207 ( 0.6A)
HIS  A 204 ( 1.0A)
 0.85A 6e43D-5svdA:
1.9		 6e43D-5svdA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vrq ANKYRIN
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila) 		no annotation 4 VAL A 339
LEU A 321
LEU A 366
HIS A 365
 None
 0.89A 6e43D-5vrqA:
undetectable		 6e43D-5vrqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5whr INDOLEAMINE
2,3-DIOXYGENASE 1

(Homo sapiens) 		no annotation 5 VAL A 269
LEU A 339
LEU A 342
ARG A 343
HIS A 346
 None
None
None
HEM  A 501 (-3.9A)
HEM  A 501 (-3.2A)
 0.77A 6e43D-5whrA:
58.8		 6e43D-5whrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfa NAD-REDUCING
HYDROGENASE
NAD-REDUCING
HYDROGENASE

(Hydrogenophilus
thermoluteolus;
Hydrogenophilus
thermoluteolus) 		PF01257
(2Fe-2S_thioredx)
PF01512
(Complex1_51K)
PF10589
(NADH_4Fe-4S)
PF01058
(Oxidored_q6) 		4 PHE A 559
VAL C  70
LEU A 581
LEU A 561
 None
 0.97A 6e43D-5xfaA:
undetectable		 6e43D-5xfaA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6h FLAGELLAR BRAKE
PROTEIN YCGR

(Escherichia
coli) 		no annotation 4 LEU A  17
LEU A  20
ARG A  21
HIS A  24
 None
 0.78A 6e43D-5y6hA:
undetectable		 6e43D-5y6hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yeu -

(-) 		no annotation 4 VAL A 462
LEU A 475
LEU A 472
HIS A 468
 None
 0.88A 6e43D-5yeuA:
undetectable		 6e43D-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yim SDEA

(Legionella
pneumophila) 		no annotation 4 PHE A 448
LEU A 568
LEU A 571
HIS A 575
 None
 0.63A 6e43D-5yimA:
3.0		 6e43D-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zq4 SIDE

(Legionella
pneumophila) 		no annotation 4 PHE B 444
LEU B 566
LEU B 569
HIS B 573
 None
 0.53A 6e43D-5zq4B:
undetectable		 6e43D-5zq4B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zq6 SIDE

(Legionella
pneumophila) 		no annotation 4 PHE A 444
LEU A 566
LEU A 569
HIS A 573
 None
 0.59A 6e43D-5zq6A:
undetectable		 6e43D-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0b TOXIN B

(Clostridioides
difficile) 		no annotation 4 PHE A1782
VAL A1719
LEU A1776
LEU A1780
 None
 0.84A 6e43D-6c0bA:
undetectable		 6e43D-6c0bA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g0c UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA

(Legionella
pneumophila) 		no annotation 4 PHE A 448
LEU A 568
LEU A 571
HIS A 575
 None
 0.73A 6e43D-6g0cA:
undetectable		 6e43D-6g0cA:
undetectable