SIMILAR PATTERNS OF AMINO ACIDS FOR 6E43_B_BEZB502_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1csy SYK PROTEIN TYROSINE
KINASE

(Homo sapiens) 		PF00017
(SH2) 		4 PHE A  16
LEU A  73
LEU A  84
HIS A  10
 None
 0.94A 6e43B-1csyA:
0.0		 6e43B-1csyA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1de3 RIBONUCLEASE
ALPHA-SARCIN

(Aspergillus
giganteus) 		no annotation 4 VAL A 122
LEU A  94
LEU A  95
HIS A  50
 None
 0.97A 6e43B-1de3A:
undetectable		 6e43B-1de3A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dov ALPHA-CATENIN

(Mus musculus) 		PF01044
(Vinculin) 		4 VAL A  91
LEU A 141
LEU A 138
ARG A 137
 None
 0.95A 6e43B-1dovA:
2.2		 6e43B-1dovA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f26 NITRIC OXIDE
REDUCTASE

(Fusarium
oxysporum) 		PF00067
(p450) 		4 VAL A 252
LEU A 265
LEU A 262
HIS A 258
 None
 0.99A 6e43B-1f26A:
0.0		 6e43B-1f26A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4r MERLIN

(Homo sapiens) 		PF00373
(FERM_M)
PF09379
(FERM_N)
PF09380
(FERM_C) 		4 VAL A  24
LEU A  75
LEU A  64
HIS A  95
 None
 1.03A 6e43B-1h4rA:
0.0		 6e43B-1h4rA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k2p TYROSINE-PROTEIN
KINASE BTK

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LEU A 483
LEU A 486
ARG A 487
HIS A 491
 None
 1.03A 6e43B-1k2pA:
0.0		 6e43B-1k2pA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kw2 VITAMIN D-BINDING
PROTEIN

(Homo sapiens) 		PF00273
(Serum_albumin)
PF09164
(VitD-bind_III) 		4 PHE A 385
VAL A 342
LEU A 369
LEU A 372
 None
 0.83A 6e43B-1kw2A:
0.0		 6e43B-1kw2A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m2w MANNITOL
DEHYDROGENASE

(Pseudomonas
fluorescens) 		PF01232
(Mannitol_dh)
PF08125
(Mannitol_dh_C) 		4 PHE A 184
VAL A 165
LEU A 115
LEU A 119
 None
 0.91A 6e43B-1m2wA:
0.0		 6e43B-1m2wA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mtp SERINE PROTEINASE
INHIBITOR (SERPIN),
CHAIN A
SERINE PROTEINASE
INHIBITOR (SERPIN),
CHAIN B

(Thermobifida
fusca;
Thermobifida
fusca) 		PF00079
(Serpin)
no annotation 		4 VAL B 345
LEU A  17
LEU A  13
HIS A  12
 None
 0.96A 6e43B-1mtpB:
undetectable		 6e43B-1mtpB:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1psu PHENYLACETIC ACID
DEGRADATION PROTEIN
PAAI

(Escherichia
coli) 		PF03061
(4HBT) 		4 VAL A  40
LEU A  59
LEU A  56
HIS A  52
 None
 1.02A 6e43B-1psuA:
undetectable		 6e43B-1psuA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r3d CONSERVED
HYPOTHETICAL PROTEIN
VC1974

(Vibrio cholerae) 		PF12697
(Abhydrolase_6) 		4 PHE A 221
LEU A  92
ARG A  95
HIS A 120
 None
 0.92A 6e43B-1r3dA:
undetectable		 6e43B-1r3dA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s9i DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 PHE A 345
VAL A 177
LEU A 360
LEU A 363
 None
 0.58A 6e43B-1s9iA:
undetectable		 6e43B-1s9iA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sv1 CIRCADIAN CLOCK
PROTEIN KAIA

(Thermosynechococcus
elongatus) 		PF07688
(KaiA) 		4 PHE A  42
LEU A  14
LEU A  17
ARG A  18
 None
 1.00A 6e43B-1sv1A:
2.3		 6e43B-1sv1A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9s URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Thermus
thermophilus) 		PF14681
(UPRTase) 		4 PHE A  28
LEU A  15
LEU A  18
ARG A  19
 None
 0.94A 6e43B-1v9sA:
undetectable		 6e43B-1v9sA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xtt PROBABLE URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Sulfolobus
solfataricus) 		PF14681
(UPRTase) 		4 PHE A  28
LEU A  15
LEU A  18
ARG A  19
 None
 1.03A 6e43B-1xttA:
undetectable		 6e43B-1xttA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csd TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 VAL A 232
LEU A 154
LEU A 146
ARG A 151
 None
 0.93A 6e43B-2csdA:
undetectable		 6e43B-2csdA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cyc TYROSYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00579
(tRNA-synt_1b) 		4 PHE A 298
VAL A 343
LEU A 334
LEU A 325
 None
 0.97A 6e43B-2cycA:
undetectable		 6e43B-2cycA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2di3 BACTERIAL REGULATORY
PROTEINS, GNTR
FAMILY

(Corynebacterium
glutamicum) 		PF00392
(GntR)
PF07729
(FCD) 		4 VAL A 150
LEU A 203
LEU A 200
HIS A 196
 None
None
None
ZN  A1002 (-3.3A)
 0.69A 6e43B-2di3A:
undetectable		 6e43B-2di3A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ebn ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1

(Elizabethkingia
meningoseptica) 		PF00704
(Glyco_hydro_18) 		4 PHE A 224
VAL A  39
LEU A 278
LEU A 266
 None
 1.03A 6e43B-2ebnA:
undetectable		 6e43B-2ebnA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g2d ATP:COBALAMIN
ADENOSYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF01923
(Cob_adeno_trans) 		4 VAL A 175
LEU A 125
LEU A 129
HIS A 130
 None
 1.02A 6e43B-2g2dA:
2.0		 6e43B-2g2dA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iht CARBOXYETHYLARGININE
SYNTHASE

(Streptomyces
clavuligerus) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 PHE A 458
LEU A 540
LEU A 543
ARG A 544
 None
 0.95A 6e43B-2ihtA:
undetectable		 6e43B-2ihtA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iqc FANCONI ANEMIA GROUP
F PROTEIN

(Homo sapiens) 		PF11107
(FANCF) 		4 VAL A 325
LEU A 351
LEU A 354
ARG A 355
 None
 0.90A 6e43B-2iqcA:
undetectable		 6e43B-2iqcA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2irm MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 7
INTERACTING PROTEIN
1

(Anopheles
gambiae) 		PF00481
(PP2C) 		4 PHE A 227
VAL A 261
LEU A 220
LEU A 222
 None
 0.94A 6e43B-2irmA:
undetectable		 6e43B-2irmA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jv3 ETS1 PROTO-ONCOGENE

(Mus musculus) 		PF02198
(SAM_PNT) 		4 PHE A 113
VAL A  77
LEU A 132
LEU A 129
 None
 0.92A 6e43B-2jv3A:
undetectable		 6e43B-2jv3A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2owo DNA LIGASE

(Escherichia
coli) 		PF01653
(DNA_ligase_aden)
PF03119
(DNA_ligase_ZBD)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 VAL A 170
LEU A 235
ARG A 242
HIS A 239
 None
 0.97A 6e43B-2owoA:
undetectable		 6e43B-2owoA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q66 POLY(A) POLYMERASE

(Saccharomyces
cerevisiae) 		PF01909
(NTP_transf_2)
PF04926
(PAP_RNA-bind)
PF04928
(PAP_central) 		4 PHE A  85
VAL A 165
LEU A 176
LEU A 171
 None
 1.01A 6e43B-2q66A:
undetectable		 6e43B-2q66A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2re3 UNCHARACTERIZED
PROTEIN

(Ruegeria
pomeroyi) 		PF06938
(DUF1285) 		4 PHE A  95
VAL A  63
LEU A  79
LEU A  70
 None
 0.96A 6e43B-2re3A:
undetectable		 6e43B-2re3A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uzx HEPATOCYTE GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG) 		5 PHE B 146
VAL B  72
LEU B 120
LEU B 130
HIS B  58
 None
 1.38A 6e43B-2uzxB:
undetectable		 6e43B-2uzxB:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w9x PUTATIVE ACETYL
XYLAN ESTERASE

(Cellvibrio
japonicus) 		PF00657
(Lipase_GDSL) 		4 VAL A 324
LEU A 345
LEU A 348
HIS A 352
 None
 0.93A 6e43B-2w9xA:
undetectable		 6e43B-2w9xA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2woo ATPASE GET3

(Schizosaccharomyces
pombe) 		PF02374
(ArsA_ATPase) 		4 PHE A 313
VAL A 227
LEU A  10
LEU A 317
 None
 1.00A 6e43B-2wooA:
undetectable		 6e43B-2wooA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yjn GLYCOSYLTRANSFERASE

(Saccharopolyspora
erythraea) 		PF06722
(DUF1205) 		4 VAL A 397
LEU A 383
LEU A 361
HIS A 341
 None
 1.00A 6e43B-2yjnA:
undetectable		 6e43B-2yjnA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zcn BIOFILM OPERON
ICAABCD HTH-TYPE
NEGATIVE
TRANSCRIPTIONAL
REGULATOR ICAR

(Staphylococcus
epidermidis) 		PF00440
(TetR_N) 		4 PHE A 147
VAL A 181
LEU A 135
LEU A 143
 None
 1.00A 6e43B-2zcnA:
3.0		 6e43B-2zcnA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zoa PHOSPHOHYDROLASE

(Klebsiella
aerogenes) 		PF00149
(Metallophos) 		4 PHE A  11
VAL A  31
LEU A  70
LEU A  67
 None
 0.89A 6e43B-2zoaA:
undetectable		 6e43B-2zoaA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3buj CALO2

(Micromonospora
echinospora) 		PF00067
(p450) 		4 VAL A 246
LEU A 259
LEU A 256
HIS A 252
 None
 1.02A 6e43B-3bujA:
undetectable		 6e43B-3bujA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ejb BIOTIN BIOSYNTHESIS
CYTOCHROME P450-LIKE
ENZYME

(Bacillus
subtilis) 		PF00067
(p450) 		4 VAL B 247
LEU B 260
LEU B 257
HIS B 253
 None
None
None
CL  B 406 (-4.7A)
 0.92A 6e43B-3ejbB:
undetectable		 6e43B-3ejbB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcy XYLAN ESTERASE 1

(Thermoanaerobacterium
saccharolyticum) 		PF05448
(AXE1) 		4 VAL A 268
LEU A   8
LEU A  11
ARG A  12
 None
 1.02A 6e43B-3fcyA:
undetectable		 6e43B-3fcyA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhl PUTATIVE
OXIDOREDUCTASE

(Bacteroides
fragilis) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 PHE A 189
VAL A 132
LEU A 141
LEU A 144
 None
 1.00A 6e43B-3fhlA:
undetectable		 6e43B-3fhlA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdb PUTATIVE
UNCHARACTERIZED
PROTEIN SPR0440

(Streptococcus
pneumoniae) 		PF03644
(Glyco_hydro_85) 		4 PHE A 693
LEU A 698
LEU A 695
HIS A 625
 None
 1.02A 6e43B-3gdbA:
undetectable		 6e43B-3gdbA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0r ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Aquifex
aeolicus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		4 PHE B 329
VAL B 397
LEU B 375
LEU B 372
 None
 0.82A 6e43B-3h0rB:
undetectable		 6e43B-3h0rB:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hf8 TRYPTOPHAN
5-HYDROXYLASE 1

(Homo sapiens) 		PF00351
(Biopterin_H) 		4 PHE A 227
VAL A 316
LEU A 242
LEU A 245
 None
 1.03A 6e43B-3hf8A:
undetectable		 6e43B-3hf8A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hn2 2-DEHYDROPANTOATE
2-REDUCTASE

(Geobacter
metallireducens) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 VAL A  26
LEU A  42
LEU A  53
HIS A  55
 None
 0.95A 6e43B-3hn2A:
undetectable		 6e43B-3hn2A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hqg TYPE-2 RESTRICTION
ENZYME ECORII

(Escherichia
coli) 		PF09019
(EcoRII-C) 		4 PHE A 278
VAL A 369
LEU A 270
LEU A 274
 None
 1.03A 6e43B-3hqgA:
undetectable		 6e43B-3hqgA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE
FAD-SUBUNIT

(Eubacterium
barkeri) 		PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C) 		4 PHE C 230
VAL C 278
LEU C 251
LEU C 254
 None
 0.96A 6e43B-3hrdC:
undetectable		 6e43B-3hrdC:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibg ATPASE, SUBUNIT OF
THE GET COMPLEX

(Aspergillus
fumigatus) 		PF02374
(ArsA_ATPase) 		4 PHE A 328
VAL A 241
LEU A  17
LEU A 332
 ADP  A 349 (-4.5A)
None
None
None
 0.90A 6e43B-3ibgA:
undetectable		 6e43B-3ibgA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3io3 DEHA2D07832P

(Debaryomyces
hansenii) 		PF02374
(ArsA_ATPase) 		4 PHE A 325
VAL A 237
LEU A   9
LEU A 329
 ADP  A 590 (-4.6A)
None
None
None
 0.89A 6e43B-3io3A:
undetectable		 6e43B-3io3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd9 COENZYME A DISULFIDE
REDUCTASE

(Pyrococcus
horikoshii) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 PHE A 330
VAL A 174
LEU A 206
LEU A 200
HIS A 203
 None
 1.38A 6e43B-3kd9A:
undetectable		 6e43B-3kd9A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis) 		no annotation 4 VAL A 399
LEU A 322
LEU A 316
HIS A 317
 None
None
None
FMT  A 510 (-4.1A)
 1.03A 6e43B-3ll7A:
undetectable		 6e43B-3ll7A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7d TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24) 		4 VAL A 232
LEU A 154
LEU A 146
ARG A 151
 None
 0.99A 6e43B-3m7dA:
2.0		 6e43B-3m7dA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7g TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13404
(HTH_AsnC-type) 		4 VAL A 232
LEU A 154
LEU A 146
ARG A 151
 None
 0.99A 6e43B-3m7gA:
1.9		 6e43B-3m7gA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mgx PUTATIVE P450
MONOOXYGENASE

(Amycolatopsis
balhimycina) 		PF00067
(p450) 		4 VAL A 193
LEU A 164
LEU A 167
HIS A 188
 None
 1.03A 6e43B-3mgxA:
undetectable		 6e43B-3mgxA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rri GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Alicyclobacillus
acidocaldarius) 		PF00903
(Glyoxalase) 		4 PHE A  72
LEU A  84
LEU A  81
HIS A  77
 None
 0.88A 6e43B-3rriA:
undetectable		 6e43B-3rriA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vkg DYNEIN HEAVY CHAIN,
CYTOPLASMIC

(Dictyostelium
discoideum) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 PHE A2691
VAL A2657
LEU A2670
LEU A2664
 None
 1.03A 6e43B-3vkgA:
undetectable		 6e43B-3vkgA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wig DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1

(Homo sapiens) 		PF00069
(Pkinase) 		4 PHE A 337
VAL A 174
LEU A 352
LEU A 355
 None
 0.67A 6e43B-3wigA:
undetectable		 6e43B-3wigA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zcw KINESIN-LIKE PROTEIN
KIF11

(Homo sapiens) 		PF00225
(Kinesin) 		4 PHE A  68
LEU A 347
LEU A 350
HIS A 354
 None
 0.80A 6e43B-3zcwA:
undetectable		 6e43B-3zcwA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4be9 STEROL ESTERASE

(Ophiostoma
piceae) 		PF00135
(COesterase) 		4 PHE A 297
LEU A 286
LEU A 289
ARG A 290
 None
 1.03A 6e43B-4be9A:
undetectable		 6e43B-4be9A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fc9 UNCHARACTERIZED
PROTEIN

(Xanthomonas
euvesicatoria) 		no annotation 4 VAL B 595
LEU B 537
LEU B 585
HIS B 584
 None
 1.01A 6e43B-4fc9B:
undetectable		 6e43B-4fc9B:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fnq ALPHA-GALACTOSIDASE
AGAB

(Geobacillus
stearothermophilus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		4 PHE A 343
VAL A 385
LEU A 410
LEU A 365
 None
 0.99A 6e43B-4fnqA:
undetectable		 6e43B-4fnqA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gdl AUTOPHAGY PROTEIN 5

(Homo sapiens) 		PF04106
(APG5) 		4 VAL B 222
LEU B 215
LEU B 251
HIS B 213
 None
 0.99A 6e43B-4gdlB:
undetectable		 6e43B-4gdlB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfj TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 VAL A 232
LEU A 154
LEU A 146
ARG A 151
 None
 1.01A 6e43B-4gfjA:
2.1		 6e43B-4gfjA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4glx DNA LIGASE

(Escherichia
coli) 		PF01653
(DNA_ligase_aden)
PF03119
(DNA_ligase_ZBD)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 VAL A 170
LEU A 235
ARG A 242
HIS A 239
 None
 0.97A 6e43B-4glxA:
undetectable		 6e43B-4glxA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gzu FERM, RHOGEF AND
PLECKSTRIN
DOMAIN-CONTAINING
PROTEIN 2

(Mus musculus) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 VAL A 646
LEU A 736
LEU A 733
ARG A 732
 None
 0.98A 6e43B-4gzuA:
3.3		 6e43B-4gzuA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus) 		no annotation 4 VAL A  79
LEU A 292
LEU A 296
HIS A   9
 None
 0.97A 6e43B-4lc9A:
undetectable		 6e43B-4lc9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4myd 2-SUCCINYL-6-HYDROXY
-2,4-CYCLOHEXADIENE-
1-CARBOXYLATE
SYNTHASE

(Escherichia
coli) 		PF12697
(Abhydrolase_6) 		4 PHE A 213
LEU A  87
ARG A  90
HIS A 112
 None
164  A 301 (-4.0A)
164  A 301 (-3.6A)
None
 0.95A 6e43B-4mydA:
undetectable		 6e43B-4mydA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pl2 DUAL-SPECIFICITY RNA
METHYLTRANSFERASE
RLMN

(Escherichia
coli) 		no annotation 4 PHE B 330
LEU B 298
LEU B 295
HIS B 291
 None
 0.88A 6e43B-4pl2B:
undetectable		 6e43B-4pl2B:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s15 NUCLEAR RECEPTOR
ROR-ALPHA

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 PHE A 399
LEU A 477
LEU A 480
HIS A 484
 None
 0.72A 6e43B-4s15A:
undetectable		 6e43B-4s15A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ueu TYROSINE KINASE AS -
A COMMON ANCESTOR OF
SRC AND ABL

(synthetic
construct) 		PF07714
(Pkinase_Tyr) 		4 LEU A  90
LEU A  93
ARG A  94
HIS A  99
 None
 1.01A 6e43B-4ueuA:
undetectable		 6e43B-4ueuA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzw PUMILIO
DOMAIN-CONTAINING
PROTEIN KIAA0020

(Homo sapiens) 		PF08144
(CPL) 		4 VAL A 502
LEU A 561
LEU A 558
HIS A 555
 None
 0.92A 6e43B-4wzwA:
2.7		 6e43B-4wzwA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ydq PROLINE--TRNA LIGASE

(Plasmodium
falciparum) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF09180
(ProRS-C_1) 		4 VAL A 367
LEU A 380
LEU A 382
HIS A 411
 None
None
None
HFG  A 802 (-4.5A)
 0.96A 6e43B-4ydqA:
undetectable		 6e43B-4ydqA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yo5 TSSA

(Escherichia
coli) 		PF16989
(T6SS_VasJ) 		4 PHE A 480
VAL A 525
LEU A 512
LEU A 515
 None
 0.78A 6e43B-4yo5A:
3.8		 6e43B-4yo5A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z5p CYTOCHROME P450
HYDROXYLASE

(Streptomyces
atroolivaceus) 		PF00067
(p450) 		4 VAL A 249
LEU A 262
LEU A 259
HIS A 255
 None
 1.02A 6e43B-4z5pA:
undetectable		 6e43B-4z5pA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a98 POLYHEDRIN

(Cypovirus 15) 		no annotation 4 PHE A  53
LEU A 124
LEU A 187
HIS A  55
 None
 1.02A 6e43B-5a98A:
undetectable		 6e43B-5a98A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5avi OXYSTEROLS RECEPTOR
LXR-ALPHA

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 PHE A 335
LEU A 414
LEU A 417
HIS A 421
 4KM  A 501 (-4.6A)
None
None
4KM  A 501 ( 4.8A)
 0.83A 6e43B-5aviA:
undetectable		 6e43B-5aviA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bmq ERFK/YBIS/YCFS/YNHG
FAMILY PROTEIN

(Stackebrandtia
nassauensis) 		PF03734
(YkuD) 		4 VAL A 212
LEU A 284
LEU A 256
HIS A 257
 None
 0.78A 6e43B-5bmqA:
undetectable		 6e43B-5bmqA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bxi NUCLEOSIDE
DIPHOSPHATE KINASE

(Toxoplasma
gondii) 		PF00334
(NDK) 		4 VAL A  13
LEU A  93
LEU A 106
ARG A 107
 None
None
None
BCT  A 201 (-4.6A)
 0.73A 6e43B-5bxiA:
undetectable		 6e43B-5bxiA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cwe CYTOCHROME P450
HYDROXYLASE

(Streptomyces
avermitilis) 		PF00067
(p450) 		4 VAL A 246
LEU A 259
LEU A 256
HIS A 252
 None
 1.01A 6e43B-5cweA:
undetectable		 6e43B-5cweA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5din LIGAND OF NUMB
PROTEIN X 2

(Homo sapiens) 		PF13923
(zf-C3HC4_2) 		4 VAL A  30
LEU A  88
LEU A  91
ARG A 107
 None
 1.00A 6e43B-5dinA:
undetectable		 6e43B-5dinA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g06 EXOSOME COMPLEX
COMPONENT RRP40

(Saccharomyces
cerevisiae) 		PF15985
(KH_6) 		4 PHE G 231
VAL G 196
LEU G 175
LEU G 178
 None
 0.77A 6e43B-5g06G:
undetectable		 6e43B-5g06G:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hci GPN-LOOP GTPASE 1

(Saccharomyces
cerevisiae) 		PF03029
(ATP_bind_1) 		4 PHE A  19
VAL A 252
LEU A  27
LEU A  23
 None
 0.98A 6e43B-5hciA:
undetectable		 6e43B-5hciA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hm5 TOPOISOMERASE V

(Methanopyrus
kandleri) 		PF13412
(HTH_24)
PF14520
(HHH_5) 		4 VAL A 232
LEU A 154
LEU A 146
ARG A 151
 None
 0.98A 6e43B-5hm5A:
undetectable		 6e43B-5hm5A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hr6 RLMN METHYLASE

(Escherichia
coli) 		PF04055
(Radical_SAM) 		4 PHE A 330
LEU A 298
LEU A 295
HIS A 291
 None
 0.90A 6e43B-5hr6A:
undetectable		 6e43B-5hr6A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5icg (S)-NORCOCLAURINE
6-O-METHYLTRANSFERAS
E

(Thalictrum
flavum) 		PF00891
(Methyltransf_2)
PF08100
(Dimerisation) 		4 PHE A  79
VAL A  27
LEU A  34
LEU A  36
 None
 1.01A 6e43B-5icgA:
undetectable		 6e43B-5icgA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqc LMO1076 PROTEIN

(Listeria
monocytogenes) 		PF13457
(SH3_8) 		4 PHE A 408
VAL A 395
LEU A 352
LEU A 403
 None
 0.96A 6e43B-5jqcA:
undetectable		 6e43B-5jqcA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzd N-ACETYLNEURAMINATE
LYASE

(Staphylococcus
aureus) 		PF00701
(DHDPS) 		4 PHE A 276
LEU A 287
LEU A 284
HIS A 280
 None
 0.85A 6e43B-5kzdA:
undetectable		 6e43B-5kzdA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ltv CHEMOTACTIC
TRANSDUCER PCTC

(Pseudomonas
aeruginosa) 		PF02743
(dCache_1) 		4 VAL A 261
LEU A 207
LEU A 208
HIS A 209
 None
 0.99A 6e43B-5ltvA:
undetectable		 6e43B-5ltvA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mio KINESIN-LIKE PROTEIN
KIF2C,KIF2C FUSED TO
A DARPIN,KIF2C FUSED
TO A DARPIN

(Homo sapiens) 		PF00023
(Ank)
PF00225
(Kinesin)
PF12796
(Ank_2) 		4 PHE C 311
LEU C 576
LEU C 579
ARG C 580
 None
 0.97A 6e43B-5mioC:
undetectable		 6e43B-5mioC:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqi PROTEIN TIMELESS
HOMOLOG,PROTEIN
TIMELESS HOMOLOG

(Homo sapiens) 		PF04821
(TIMELESS) 		4 PHE A  79
LEU A  66
LEU A  69
HIS A  73
 None
 1.02A 6e43B-5mqiA:
5.0		 6e43B-5mqiA:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5svd NUCLEOLAR PROTEIN 9

(Saccharomyces
cerevisiae) 		PF00806
(PUF) 		4 LEU A 211
LEU A 208
ARG A 207
HIS A 204
 LEU  A 211 ( 0.6A)
LEU  A 208 ( 0.5A)
ARG  A 207 ( 0.6A)
HIS  A 204 ( 1.0A)
 0.92A 6e43B-5svdA:
3.3		 6e43B-5svdA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u99 ATP
PHOSPHORIBOSYLTRANSF
ERASE

(Mycobacterium
tuberculosis) 		PF01634
(HisG)
PF08029
(HisG_C) 		4 PHE A  87
VAL A   6
LEU A 181
LEU A  85
 None
 1.01A 6e43B-5u99A:
undetectable		 6e43B-5u99A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vrq ANKYRIN
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila) 		no annotation 4 VAL A 339
LEU A 321
LEU A 366
HIS A 365
 None
 1.00A 6e43B-5vrqA:
undetectable		 6e43B-5vrqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5whr INDOLEAMINE
2,3-DIOXYGENASE 1

(Homo sapiens) 		no annotation 5 VAL A 269
LEU A 339
LEU A 342
ARG A 343
HIS A 346
 None
None
None
HEM  A 501 (-3.9A)
HEM  A 501 (-3.2A)
 0.71A 6e43B-5whrA:
27.8		 6e43B-5whrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x4t PHOTOACTIVATED
ADENYLYL CYCLASE

(Cyanobacteria) 		PF00211
(Guanylate_cyc)
PF04940
(BLUF) 		4 PHE A 163
LEU A 225
LEU A 241
ARG A 229
 None
 1.03A 6e43B-5x4tA:
undetectable		 6e43B-5x4tA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfa NAD-REDUCING
HYDROGENASE
NAD-REDUCING
HYDROGENASE

(Hydrogenophilus
thermoluteolus;
Hydrogenophilus
thermoluteolus) 		PF01257
(2Fe-2S_thioredx)
PF01512
(Complex1_51K)
PF10589
(NADH_4Fe-4S)
PF01058
(Oxidored_q6) 		4 PHE A 559
VAL C  70
LEU A 581
LEU A 561
 None
 0.98A 6e43B-5xfaA:
undetectable		 6e43B-5xfaA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6h FLAGELLAR BRAKE
PROTEIN YCGR

(Escherichia
coli) 		no annotation 4 LEU A  17
LEU A  20
ARG A  21
HIS A  24
 None
 0.87A 6e43B-5y6hA:
undetectable		 6e43B-5y6hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yeu -

(-) 		no annotation 4 VAL A 462
LEU A 475
LEU A 472
HIS A 468
 None
 0.88A 6e43B-5yeuA:
undetectable		 6e43B-5yeuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yim SDEA

(Legionella
pneumophila) 		no annotation 4 PHE A 448
LEU A 568
LEU A 571
HIS A 575
 None
 0.62A 6e43B-5yimA:
2.7		 6e43B-5yimA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zq4 SIDE

(Legionella
pneumophila) 		no annotation 4 PHE B 444
LEU B 566
LEU B 569
HIS B 573
 None
 0.56A 6e43B-5zq4B:
undetectable		 6e43B-5zq4B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zq6 SIDE

(Legionella
pneumophila) 		no annotation 4 PHE A 444
LEU A 566
LEU A 569
HIS A 573
 None
 0.61A 6e43B-5zq6A:
undetectable		 6e43B-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a8m -

(-) 		no annotation 4 PHE A  12
VAL A  68
LEU A  52
LEU A  56
 None
 0.92A 6e43B-6a8mA:
undetectable		 6e43B-6a8mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0b TOXIN B

(Clostridioides
difficile) 		no annotation 4 PHE A1782
VAL A1719
LEU A1776
LEU A1780
 None
 0.82A 6e43B-6c0bA:
undetectable		 6e43B-6c0bA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g0c UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA

(Legionella
pneumophila) 		no annotation 4 PHE A 448
LEU A 568
LEU A 571
HIS A 575
 None
 0.75A 6e43B-6g0cA:
undetectable		 6e43B-6g0cA:
undetectable