SIMILAR PATTERNS OF AMINO ACIDS FOR 6DWN_C_AQ4C602_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1akc ASPARTATE
AMINOTRANSFERASE

(Gallus gallus) 		PF00155
(Aminotran_1_2) 		3 SER A 253
SER A 111
ALA A 257
 None
None
PPE  A 411 ( 3.8A)
 0.68A 6dwnC-1akcA:
0.0		 6dwnC-1akcA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)

(Cupriavidus
necator) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		3 SER A  65
SER A  64
ALA A  87
 None
 0.72A 6dwnC-1bxnA:
0.0		 6dwnC-1bxnA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dm0 SHIGA TOXIN A
SUBUNIT

(Shigella
dysenteriae) 		PF00161
(RIP) 		3 SER A 279
SER A 280
ALA A 263
 None
 0.67A 6dwnC-1dm0A:
0.0		 6dwnC-1dm0A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus) 		PF04616
(Glyco_hydro_43) 		3 SER B 147
SER B 119
ALA B 215
 None
 0.66A 6dwnC-1gydB:
undetectable		 6dwnC-1gydB:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j0n XANTHAN LYASE

(Bacillus sp.
GL1) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		3 SER A 720
SER A 704
ALA A 399
 None
 0.58A 6dwnC-1j0nA:
0.0		 6dwnC-1j0nA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfu M-CALPAIN LARGE
SUBUNIT

(Homo sapiens) 		PF00648
(Peptidase_C2)
PF01067
(Calpain_III)
PF13833
(EF-hand_8) 		3 SER L 241
SER L 336
ALA L 199
 None
 0.48A 6dwnC-1kfuL:
0.2		 6dwnC-1kfuL:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kpi CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 2

(Mycobacterium
tuberculosis) 		PF02353
(CMAS) 		3 SER A  85
SER A  38
ALA A  44
 SAH  A 900 ( 4.4A)
None
None
 0.52A 6dwnC-1kpiA:
0.0		 6dwnC-1kpiA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l1o REPLICATION PROTEIN
A 32 KDA SUBUNIT
REPLICATION PROTEIN
A 70 KDA DNA-BINDING
SUBUNIT

(Homo sapiens;
Homo sapiens) 		no annotation
PF08646
(Rep_fac-A_C) 		3 SER C 613
SER C 609
ALA B 165
 None
 0.71A 6dwnC-1l1oC:
undetectable		 6dwnC-1l1oC:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n5x XANTHINE
DEHYDROGENASE

(Bos taurus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		3 SER A 123
SER A  69
ALA A 338
 None
None
FAD  A3005 (-3.5A)
 0.73A 6dwnC-1n5xA:
undetectable		 6dwnC-1n5xA:
4.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nio B-LUFFIN

(Luffa
aegyptiaca) 		PF00161
(RIP) 		3 SER A 100
SER A  81
ALA A  92
 None
 0.74A 6dwnC-1nioA:
undetectable		 6dwnC-1nioA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o5i 3-OXOACYL-(ACYL
CARRIER PROTEIN)
REDUCTASE

(Thermotoga
maritima) 		PF13561
(adh_short_C2) 		3 SER A 128
SER A 130
ALA A  82
 None
 0.71A 6dwnC-1o5iA:
0.7		 6dwnC-1o5iA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pe9 PECTATE LYASE A

(Dickeya
chrysanthemi) 		PF00544
(Pec_lyase_C) 		3 SER A  81
SER A 104
ALA A 141
 None
 0.70A 6dwnC-1pe9A:
undetectable		 6dwnC-1pe9A:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rwr FILAMENTOUS
HEMAGGLUTININ

(Bordetella
pertussis) 		PF05860
(Haemagg_act) 		3 SER A 257
SER A 234
ALA A 214
 None
 0.67A 6dwnC-1rwrA:
undetectable		 6dwnC-1rwrA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s5l PHOTOSYSTEM II
MANGANESE-STABILIZIN
G POLYPEPTIDE

(Thermosynechococcus
elongatus) 		PF01716
(MSP) 		3 SER O 191
SER O 150
ALA O 227
 None
 0.59A 6dwnC-1s5lO:
undetectable		 6dwnC-1s5lO:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txc PATHOGENESIS-RELATED
CLASS 10 PROTEIN
SPE-16

(Pachyrhizus
erosus) 		PF00407
(Bet_v_1) 		3 SER A 111
SER A  11
ALA A  21
 None
 0.59A 6dwnC-1txcA:
undetectable		 6dwnC-1txcA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5b 3-ISOPROPYLMALATE
DEHYDROGENASE

(Bacillus
coagulans) 		PF00180
(Iso_dh) 		3 SER A 299
SER A 264
ALA A  73
 None
 0.71A 6dwnC-1v5bA:
undetectable		 6dwnC-1v5bA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6o FERRITIN LIGHT CHAIN
FERRITIN HEAVY CHAIN

(Trichoplusia
ni;
Trichoplusia ni) 		PF00210
(Ferritin)
PF00210
(Ferritin) 		3 SER A  80
SER A  52
ALA M  71
 None
 0.72A 6dwnC-1z6oA:
undetectable		 6dwnC-1z6oA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9m FLUORESCEIN-SCFV
HEAVY CHAIN

(Homo sapiens) 		PF07686
(V-set) 		3 SER H 113
SER H 134
ALA H 107
 None
 0.52A 6dwnC-2a9mH:
undetectable		 6dwnC-2a9mH:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9m FLUORESCEIN-SCFV
HEAVY CHAIN

(Homo sapiens) 		PF07686
(V-set) 		3 SER H 114
SER H 113
ALA H 107
 None
 0.69A 6dwnC-2a9mH:
undetectable		 6dwnC-2a9mH:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d2n GIANT HEMOGLOBIN,
A2(A5) GLOBIN CHAIN
GIANT HEMOGLOBIN,
B2(C) GLOBIN CHAIN

(Oligobrachia
mashikoi;
Oligobrachia
mashikoi) 		PF00042
(Globin)
PF00042
(Globin) 		3 SER C  25
SER B  76
ALA C  61
 None
 0.55A 6dwnC-2d2nC:
undetectable		 6dwnC-2d2nC:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ecf DIPEPTIDYL PEPTIDASE
IV

(Stenotrophomonas
maltophilia) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		3 SER A 341
SER A 353
ALA A 398
 None
 0.60A 6dwnC-2ecfA:
undetectable		 6dwnC-2ecfA:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fj0 CARBOXYLIC ESTER
HYDROLASE

(Manduca sexta) 		PF00135
(COesterase) 		3 SER A 255
SER A 256
ALA A 340
 None
 0.63A 6dwnC-2fj0A:
undetectable		 6dwnC-2fj0A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus 1) 		PF00075
(RNase_H)
PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		3 SER A 513
SER A 515
ALA A 502
 None
 0.70A 6dwnC-2hnzA:
undetectable		 6dwnC-2hnzA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ibb CG9211-PA

(Drosophila
melanogaster) 		PF00041
(fn3) 		3 SER A 656
SER A 663
ALA A 602
 None
 0.73A 6dwnC-2ibbA:
undetectable		 6dwnC-2ibbA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j1l RHO-RELATED
GTP-BINDING PROTEIN
RHOD

(Homo sapiens) 		PF00071
(Ras) 		3 SER A 193
SER A 192
ALA A 167
 None
 0.72A 6dwnC-2j1lA:
undetectable		 6dwnC-2j1lA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n2l OUTER MEMBRANE
PROTEIN X

(Yersinia pestis) 		PF13505
(OMP_b-brl) 		3 SER A 114
SER A 138
ALA A  48
 None
 0.72A 6dwnC-2n2lA:
undetectable		 6dwnC-2n2lA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8r POLYPHOSPHATE KINASE

(Porphyromonas
gingivalis) 		PF02503
(PP_kinase)
PF13089
(PP_kinase_N)
PF13090
(PP_kinase_C) 		3 SER A  45
SER A  41
ALA A 469
 None
None
SO4  A 708 (-3.3A)
 0.71A 6dwnC-2o8rA:
undetectable		 6dwnC-2o8rA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pgg RNA-DIRECTED RNA
POLYMERASE

(Infectious
bursal disease
virus) 		PF04197
(Birna_RdRp) 		3 SER A 469
SER A 314
ALA A 803
 None
 0.73A 6dwnC-2pggA:
undetectable		 6dwnC-2pggA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qp2 UNKNOWN PROTEIN

(Photorhabdus
laumondii) 		PF01823
(MACPF) 		3 SER A 216
SER A 152
ALA A 235
 None
 0.61A 6dwnC-2qp2A:
undetectable		 6dwnC-2qp2A:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r5j MAJOR CAPSID PROTEIN
L1

(Alphapapillomavirus
9) 		PF00500
(Late_protein_L1) 		3 SER A 226
SER A 227
ALA A  51
 None
 0.71A 6dwnC-2r5jA:
undetectable		 6dwnC-2r5jA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vx2 ENOYL-COA HYDRATASE
DOMAIN-CONTAINING
PROTEIN 3

(Homo sapiens) 		PF00378
(ECH_1) 		3 SER A 167
SER A 170
ALA A  98
 None
 0.69A 6dwnC-2vx2A:
undetectable		 6dwnC-2vx2A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xh6 HEAT-LABILE
ENTEROTOXIN B CHAIN

(Clostridium
perfringens) 		PF03505
(Clenterotox) 		3 SER A 145
SER A 150
ALA A 203
 None
 0.72A 6dwnC-2xh6A:
undetectable		 6dwnC-2xh6A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzo REGULATOR OF
NONSENSE TRANSCRIPTS
1

(Homo sapiens) 		PF04851
(ResIII)
PF13086
(AAA_11)
PF13087
(AAA_12) 		3 SER A 812
SER A 810
ALA A 770
 MG  A1007 (-3.0A)
MG  A1007 (-3.9A)
None
 0.59A 6dwnC-2xzoA:
undetectable		 6dwnC-2xzoA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3blx ISOCITRATE
DEHYDROGENASE [NAD]
SUBUNIT 2

(Saccharomyces
cerevisiae) 		PF00180
(Iso_dh) 		3 SER B 258
SER B 255
ALA B 297
 None
 0.72A 6dwnC-3blxB:
undetectable		 6dwnC-3blxB:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ckn PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium) 		PF00535
(Glycos_transf_2) 		3 SER A 130
SER A 126
ALA A 220
 None
 0.58A 6dwnC-3cknA:
undetectable		 6dwnC-3cknA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddr HASR PROTEIN

(Serratia
marcescens) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 SER A 278
SER A 326
ALA A 139
 None
 0.65A 6dwnC-3ddrA:
undetectable		 6dwnC-3ddrA:
6.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dp9 MTA/SAH NUCLEOSIDASE

(Vibrio cholerae) 		PF01048
(PNP_UDP_1) 		3 SER A 220
SER A 219
ALA A   8
 None
None
BIG  A 301 ( 3.8A)
 0.73A 6dwnC-3dp9A:
undetectable		 6dwnC-3dp9A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gvh MALATE DEHYDROGENASE

(Brucella
abortus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 SER A 301
SER A 179
ALA A 257
 None
 0.66A 6dwnC-3gvhA:
undetectable		 6dwnC-3gvhA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4i GLYCOSYLTRANSFERASE
GTFA,
GLYCOSYLTRANSFERASE

(Actinoplanes
teichomyceticus;
Amycolatopsis
orientalis) 		PF03033
(Glyco_transf_28)
PF04101
(Glyco_tran_28_C) 		3 SER A 230
SER A  10
ALA A 294
 U2F  A 547 (-2.6A)
U2F  A 547 (-3.0A)
U2F  A 547 (-3.5A)
 0.69A 6dwnC-3h4iA:
undetectable		 6dwnC-3h4iA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hpa AMIDOHYDROLASE

(unidentified) 		PF01979
(Amidohydro_1) 		3 SER A 349
SER A  99
ALA A 140
 None
 0.63A 6dwnC-3hpaA:
undetectable		 6dwnC-3hpaA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3im0 VAL-1

(Paramecium
bursaria
Chlorella virus
CVK2) 		no annotation 3 SER A  48
SER A 227
ALA A 233
 None
 0.68A 6dwnC-3im0A:
undetectable		 6dwnC-3im0A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j2u KINESIN-LIKE PROTEIN
KLP10A

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		3 SER K 478
SER K 487
ALA K 483
 None
 0.65A 6dwnC-3j2uK:
undetectable		 6dwnC-3j2uK:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2p REVERSE
TRANSCRIPTASE

(Human
immunodeficiency
virus 1) 		PF00075
(RNase_H) 		3 SER A 513
SER A 515
ALA A 502
 None
 0.73A 6dwnC-3k2pA:
undetectable		 6dwnC-3k2pA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Thermus
thermophilus) 		PF01425
(Amidase) 		3 SER E 141
SER E 165
ALA E 192
 None
 0.59A 6dwnC-3kfuE:
undetectable		 6dwnC-3kfuE:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Thermus
thermophilus) 		PF01425
(Amidase) 		3 SER E 141
SER E 165
ALA E 194
 None
 0.73A 6dwnC-3kfuE:
undetectable		 6dwnC-3kfuE:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lft UNCHARACTERIZED
PROTEIN

(Streptococcus
pneumoniae) 		PF04392
(ABC_sub_bind) 		3 SER A 260
SER A 259
ALA A 225
 None
 0.62A 6dwnC-3lftA:
undetectable		 6dwnC-3lftA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m4f ENDO-1,4-BETA-XYLANA
SE

(Acidomyces
acidophilus) 		PF00457
(Glyco_hydro_11) 		3 SER A  86
SER A  88
ALA A  40
 None
 0.49A 6dwnC-3m4fA:
undetectable		 6dwnC-3m4fA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntx CYTOPLASMIC
L-ASPARAGINASE I

(Yersinia pestis) 		PF00710
(Asparaginase) 		3 SER A  60
SER A  61
ALA A 166
 None
 0.65A 6dwnC-3ntxA:
0.1		 6dwnC-3ntxA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nur AMIDOHYDROLASE

(Staphylococcus
aureus) 		PF04909
(Amidohydro_2) 		3 SER A  98
SER A 100
ALA A 159
 None
 0.71A 6dwnC-3nurA:
undetectable		 6dwnC-3nurA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o4v MTA/SAH NUCLEOSIDASE

(Escherichia
coli) 		PF01048
(PNP_UDP_1) 		3 SER A 219
SER A 218
ALA A   8
 None
None
4CT  A 233 ( 3.7A)
 0.68A 6dwnC-3o4vA:
undetectable		 6dwnC-3o4vA:
14.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pm0 CYTOCHROME P450 1B1

(Homo sapiens) 		PF00067
(p450) 		3 SER A 127
SER A 131
ALA A 330
 BHF  A 800 ( 4.6A)
BHF  A 800 ( 4.7A)
HEM  A 900 ( 3.4A)
 0.62A 6dwnC-3pm0A:
48.2		 6dwnC-3pm0A:
58.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pop GILR OXIDASE

(Streptomyces
griseoflavus) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		3 SER A 274
SER A 275
ALA A 406
 None
 0.61A 6dwnC-3popA:
undetectable		 6dwnC-3popA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rh0 ARSENATE REDUCTASE

(Corynebacterium
glutamicum) 		PF01451
(LMWPc) 		3 SER A  34
SER A  15
ALA A  40
 None
OCS  A   8 ( 2.6A)
None
 0.66A 6dwnC-3rh0A:
undetectable		 6dwnC-3rh0A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t38 ARSENATE REDUCTASE

(Corynebacterium
glutamicum) 		PF01451
(LMWPc) 		3 SER A 114
SER A  95
ALA A 120
 None
 0.67A 6dwnC-3t38A:
undetectable		 6dwnC-3t38A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8x TRANSFERRIN-BINDING
PROTEIN 1

(Neisseria
meningitidis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 SER A  69
SER A  65
ALA A 208
 None
 0.73A 6dwnC-3v8xA:
undetectable		 6dwnC-3v8xA:
6.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wel ALPHA-GLUCOSIDASE

(Beta vulgaris) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16863
(NtCtMGAM_N) 		3 SER A 731
SER A 725
ALA A 745
 None
 0.53A 6dwnC-3welA:
undetectable		 6dwnC-3welA:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bla MALTOSE-BINDING
PERIPLASMIC PROTEIN,
SUPPRESSOR OF FUSED
HOMOLOG

(Escherichia
coli;
Homo sapiens) 		PF05076
(SUFU)
PF12470
(SUFU_C)
PF13416
(SBP_bac_8) 		3 SER A 454
SER A 436
ALA A 371
 None
 0.60A 6dwnC-4blaA:
undetectable		 6dwnC-4blaA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ccy CARBOXYLESTERASE
YBFK

(Bacillus
subtilis) 		PF12697
(Abhydrolase_6) 		3 SER B  50
SER B  33
ALA B  69
 None
 0.72A 6dwnC-4ccyB:
undetectable		 6dwnC-4ccyB:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cd8 ENDO-BETA-1,4-MANNAN
ASE

(Alicyclobacillus
acidocaldarius) 		no annotation 3 SER A 236
SER A 298
ALA A 292
 None
 0.68A 6dwnC-4cd8A:
undetectable		 6dwnC-4cd8A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fe9 OUTER MEMBRANE
PROTEIN SUSF

(Bacteroides
thetaiotaomicron) 		PF16411
(SusF_SusE)
PF17142
(DUF5115) 		3 SER A 344
SER A 341
ALA A 435
 None
 0.67A 6dwnC-4fe9A:
undetectable		 6dwnC-4fe9A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fys AMINOPEPTIDASE N

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 SER A 373
SER A 374
ALA A 308
 None
 0.62A 6dwnC-4fysA:
0.0		 6dwnC-4fysA:
6.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grv NEUROTENSIN RECEPTOR
TYPE 1, LYSOZYME
CHIMERA

(Rattus
norvegicus;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		3 SER A 361
SER A 362
ALA A 155
 None
 0.63A 6dwnC-4grvA:
undetectable		 6dwnC-4grvA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjc ENVELOPE
GLYCOPROTEIN

(Rift Valley
fever
phlebovirus) 		PF07245
(Phlebovirus_G2) 		3 SER A1075
SER A1054
ALA A1025
 None
 0.67A 6dwnC-4hjcA:
undetectable		 6dwnC-4hjcA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i70 INOSINE-ADENOSINE-GU
ANOSINE-NUCLEOSIDE
HYDROLASE

(Trypanosoma
brucei) 		PF01156
(IU_nuc_hydro) 		3 SER A  24
SER A 323
ALA A 262
 None
 0.54A 6dwnC-4i70A:
undetectable		 6dwnC-4i70A:
15.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		3 SER A 116
SER A 120
ALA A 317
 BHF  A 602 (-3.2A)
BHF  A 602 ( 4.5A)
BHF  A 602 ( 3.4A)
 0.30A 6dwnC-4i8vA:
60.5		 6dwnC-4i8vA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jga 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Rickettsia
rickettsii) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 SER A 351
SER A 352
ALA A 399
 None
 0.68A 6dwnC-4jgaA:
undetectable		 6dwnC-4jgaA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jjn HISTONE H2A.2
HISTONE H2B.2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00125
(Histone)
PF16211
(Histone_H2A_C)
PF00125
(Histone) 		3 SER D  58
SER D  61
ALA C  70
 None
 0.69A 6dwnC-4jjnD:
undetectable		 6dwnC-4jjnD:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k91 D-ALA-D-ALA-CARBOXYP
EPTIDASE

(Pseudomonas
aeruginosa) 		PF00768
(Peptidase_S11)
PF07943
(PBP5_C) 		3 SER A 136
SER A 151
ALA A 160
 None
 0.69A 6dwnC-4k91A:
undetectable		 6dwnC-4k91A:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ktp GLYCOSIDE HYDROLASE
FAMILY 65 CENTRAL
CATALYTIC

([Bacillus]
selenitireducens) 		PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N) 		3 SER A 323
SER A  31
ALA A 660
 None
 0.71A 6dwnC-4ktpA:
undetectable		 6dwnC-4ktpA:
7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4loa DE-NOVO DESIGN
AMIDASE

(synthetic
construct) 		PF01202
(SKI) 		3 SER A  35
SER A  81
ALA A  59
 None
 0.73A 6dwnC-4loaA:
undetectable		 6dwnC-4loaA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mt1 DRUG EFFLUX PROTEIN

(Neisseria
gonorrhoeae) 		PF00873
(ACR_tran) 		3 SER A 893
SER A 891
ALA A 962
 None
 0.71A 6dwnC-4mt1A:
undetectable		 6dwnC-4mt1A:
6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nps BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS

(Bartonella
clarridgeiae) 		PF02661
(Fic) 		3 SER A 272
SER A 275
ALA A 233
 None
 0.72A 6dwnC-4npsA:
undetectable		 6dwnC-4npsA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q76 CYSTEINE DESULFURASE
2, CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00266
(Aminotran_5) 		3 SER A 397
SER A 355
ALA A 136
 None
 0.64A 6dwnC-4q76A:
0.0		 6dwnC-4q76A:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore) 		3 SER A 776
SER A 772
ALA A 526
 None
 0.66A 6dwnC-4r04A:
undetectable		 6dwnC-4r04A:
4.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgq RIBONUCLEASE VAPC30

(Mycobacterium
tuberculosis) 		PF01850
(PIN) 		3 SER A  37
SER A  34
ALA A  79
 MG  A 201 ( 4.6A)
None
None
 0.74A 6dwnC-4xgqA:
undetectable		 6dwnC-4xgqA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z3l MAJOR POLLEN
ALLERGEN BET V 1-A

(Betula pendula) 		PF00407
(Bet_v_1) 		3 SER A 112
SER A  11
ALA A  21
 None
 0.49A 6dwnC-4z3lA:
undetectable		 6dwnC-4z3lA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a87 METALLO-BETA-LACTAMA
SE VIM-5

(Klebsiella
pneumoniae) 		PF00753
(Lactamase_B) 		3 SER A 136
SER A 138
ALA A 177
 GOL  A1264 (-2.5A)
GOL  A1264 ( 4.3A)
None
 0.73A 6dwnC-5a87A:
undetectable		 6dwnC-5a87A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9y PROTEIN LLR18A

(Lupinus luteus) 		PF00407
(Bet_v_1) 		3 SER A 111
SER A  11
ALA A  21
 None
 0.51A 6dwnC-5c9yA:
undetectable		 6dwnC-5c9yA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d2e MLNE

(Bacillus
velezensis) 		PF08659
(KR) 		3 SER A 446
SER A 407
ALA A 190
 None
 0.58A 6dwnC-5d2eA:
undetectable		 6dwnC-5d2eA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dbj FADH2-DEPENDENT
HALOGENASE PLTA

(Pseudomonas
protegens) 		no annotation 3 SER E 326
SER E  47
ALA E  77
 FAD  E 501 (-3.4A)
FAD  E 501 (-4.9A)
None
 0.54A 6dwnC-5dbjE:
0.0		 6dwnC-5dbjE:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5df0 AC-CHIA

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		3 SER A 207
SER A 203
ALA A 223
 None
 0.52A 6dwnC-5df0A:
undetectable		 6dwnC-5df0A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e05 NUCLEOCAPSID PROTEIN

(Sin Nombre
orthohantavirus) 		PF00846
(Hanta_nucleocap) 		3 SER A 163
SER A 164
ALA A 137
 None
 0.73A 6dwnC-5e05A:
undetectable		 6dwnC-5e05A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fei DISTAL TUBE PROTEIN

(Bacillus virus
phi29) 		PF16838
(Caud_tail_N) 		3 SER A 397
SER A 393
ALA A 307
 None
 0.64A 6dwnC-5feiA:
undetectable		 6dwnC-5feiA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hwq HYDROXYMETHYLGLUTARY
L-COA SYNTHASE

(Myxococcus
xanthus) 		PF01154
(HMG_CoA_synt_N)
PF08540
(HMG_CoA_synt_C) 		3 SER A 289
SER A 292
ALA A 238
 GOL  A 505 (-2.4A)
None
None
 0.67A 6dwnC-5hwqA:
undetectable		 6dwnC-5hwqA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iw7 RIBOSOME BIOGENESIS
PROTEIN
TSR1,RIBOSOME
BIOGENESIS PROTEIN
TSR1

(Saccharomyces
cerevisiae) 		PF04950
(RIBIOP_C)
PF08142
(AARP2CN) 		3 SER A 633
SER A 635
ALA A 698
 None
 0.33A 6dwnC-5iw7A:
undetectable		 6dwnC-5iw7A:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzm TRYPTOPHAN SYNTHASE
BETA CHAIN

(Francisella
tularensis) 		PF00291
(PALP) 		3 SER B 298
SER B 300
ALA B 353
 None
 0.70A 6dwnC-5kzmB:
undetectable		 6dwnC-5kzmB:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l75 FIG000906: PREDICTED
PERMEASE

(Klebsiella
pneumoniae) 		PF03739
(YjgP_YjgQ) 		3 SER G 294
SER G 352
ALA G 286
 None
 0.62A 6dwnC-5l75G:
undetectable		 6dwnC-5l75G:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mb4 GLCNAC SPECIFIC
LECTIN

(Psathyrella) 		PF13517
(VCBS) 		3 SER A   6
SER A   9
ALA A 287
 None
 0.48A 6dwnC-5mb4A:
undetectable		 6dwnC-5mb4A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mz6 SEPARASE
INTERACTOR OF FIZZY
PROTEIN

(Caenorhabditis
elegans;
Caenorhabditis
elegans) 		PF03568
(Peptidase_C50)
no annotation 		3 SER 1 176
SER 1 177
ALA B 155
 None
 0.70A 6dwnC-5mz61:
undetectable		 6dwnC-5mz61:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd1 CAPSID PROTEIN

(Rosellinia
necatrix
quadrivirus 1) 		no annotation 3 SER A 733
SER A 734
ALA A 795
 None
 0.68A 6dwnC-5nd1A:
0.0		 6dwnC-5nd1A:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nff GLYCOPROTEIN

(Morogoro
mammarenavirus) 		no annotation 3 SER B  90
SER B 196
ALA B 214
 None
None
NAG  B 301 ( 3.7A)
 0.74A 6dwnC-5nffB:
undetectable		 6dwnC-5nffB:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nms 25.3 KDA HEAT SHOCK
PROTEIN,
CHLOROPLASTIC
25.3 KDA HEAT SHOCK
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		PF00011
(HSP20)
PF00011
(HSP20) 		3 SER A 132
SER A 134
ALA B 158
 None
 0.70A 6dwnC-5nmsA:
undetectable		 6dwnC-5nmsA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Synechocystis
sp. PCC 6803) 		no annotation 3 SER b 484
SER b 481
ALA b 463
 None
LMG  b1855 (-2.8A)
None
 0.69A 6dwnC-5oy0b:
undetectable		 6dwnC-5oy0b:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3j INOSITOL
MONOPHOSPHATASE

(Medicago
truncatula) 		PF00459
(Inositol_P) 		3 SER A 281
SER A 254
ALA A 273
 None
 0.65A 6dwnC-5t3jA:
undetectable		 6dwnC-5t3jA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uc0 UNCHARACTERIZED
PROTEIN COG5400

(Brucella
abortus) 		PF06577
(DUF1134) 		3 SER A  56
SER A  58
ALA A 178
 None
 0.73A 6dwnC-5uc0A:
undetectable		 6dwnC-5uc0A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ue1 5'-METHYLTHIOADENOSI
NE/S-ADENOSYLHOMOCYS
TEINE NUCLEOSIDASE

(Aliivibrio
fischeri) 		PF01048
(PNP_UDP_1) 		3 SER A 220
SER A 219
ALA A   8
 None
None
TRS  A 302 ( 3.7A)
 0.71A 6dwnC-5ue1A:
undetectable		 6dwnC-5ue1A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w3j TUBULIN BETA CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		3 SER B 371
SER B 373
ALA B 296
 None
 0.69A 6dwnC-5w3jB:
undetectable		 6dwnC-5w3jB:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y7o UGGT

(Thermomyces
dupontii) 		PF06427
(UDP-g_GGTase) 		3 SER A 650
SER A 646
ALA A 637
 None
 0.56A 6dwnC-5y7oA:
undetectable		 6dwnC-5y7oA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cza -

(-) 		no annotation 3 SER A 191
SER A 841
ALA A 463
 None
 0.65A 6dwnC-6czaA:
undetectable		 6dwnC-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dux 6-PHOSPHO-ALPHA-GLUC
OSIDASE

(Klebsiella
pneumoniae) 		no annotation 3 SER A   5
SER A  34
ALA A  73
 None
 0.70A 6dwnC-6duxA:
undetectable		 6dwnC-6duxA:
16.05