SIMILAR PATTERNS OF AMINO ACIDS FOR 6DWN_B_AQ4B602_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b5f PROTEIN (CARDOSIN A)

(Cynara
cardunculus) 		PF00026
(Asp) 		5 ILE A 132
SER A  36
ASN A  67
PHE A  84
ILE A  73
 None
None
NAG  A 401 ( 1.8A)
NAG  A 401 ( 3.9A)
None
 1.37A 6dwnB-1b5fA:
undetectable		 6dwnB-1b5fA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ewx TRYPAREDOXIN I

(Crithidia
fasciculata) 		PF13905
(Thioredoxin_8) 		5 SER A 119
LEU A 112
PHE A  32
ASP A 116
ASP A 144
 None
 1.44A 6dwnB-1ewxA:
undetectable		 6dwnB-1ewxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f6f PLACENTAL LACTOGEN

(Ovis aries) 		PF00103
(Hormone_1) 		5 LEU A  18
PHE A  22
PHE A  83
ASP A  79
ILE A  75
 None
 1.32A 6dwnB-1f6fA:
undetectable		 6dwnB-1f6fA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8x MYOSIN II HEAVY
CHAIN FUSED TO
ALPHA-ACTININ 3

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		5 ILE A 347
SER A 343
LEU A 421
PHE A 600
ASP A 605
 None
 1.32A 6dwnB-1g8xA:
0.0		 6dwnB-1g8xA:
5.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gmi PROTEIN KINASE C,
EPSILON TYPE

(Rattus rattus) 		PF00168
(C2) 		5 ILE A  79
LEU A 106
PHE A   4
ASP A 130
ILE A  12
 None
 0.85A 6dwnB-1gmiA:
undetectable		 6dwnB-1gmiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iay 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
SYNTHASE 2

(Solanum
lycopersicum) 		PF00155
(Aminotran_1_2) 		5 ASN A 360
PHE A 365
PHE A 415
PHE A 245
ILE A 239
 None
None
None
None
PLP  A 500 (-4.6A)
 1.48A 6dwnB-1iayA:
0.0		 6dwnB-1iayA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lw3 MYOTUBULARIN-RELATED
PROTEIN 2

(Homo sapiens) 		PF02893
(GRAM)
PF06602
(Myotub-related) 		5 ILE A 544
SER A 539
LEU A 505
PHE A 445
PHE A 480
 None
 1.43A 6dwnB-1lw3A:
0.0		 6dwnB-1lw3A:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mky PROBABLE GTP-BINDING
PROTEIN ENGA

(Thermotoga
maritima) 		PF01926
(MMR_HSR1)
PF14714
(KH_dom-like) 		5 ILE A 365
PHE A 399
ASN A 366
PHE A 386
ILE A 431
 None
 1.33A 6dwnB-1mkyA:
undetectable		 6dwnB-1mkyA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v33 DNA PRIMASE SMALL
SUBUNIT

(Pyrococcus
horikoshii) 		PF01896
(DNA_primase_S) 		5 ILE A  63
LEU A 297
PHE A  14
ASP A  23
ILE A  56
 None
 1.44A 6dwnB-1v33A:
0.0		 6dwnB-1v33A:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x8v CYTOCHROME P450 51

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		5 ILE A 153
PHE A 250
LEU A 100
ASP A 224
ILE A 208
 None
 1.38A 6dwnB-1x8vA:
31.5		 6dwnB-1x8vA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zsq MYOTUBULARIN-RELATED
PROTEIN 2

(Homo sapiens) 		PF02893
(GRAM)
PF06602
(Myotub-related) 		5 ILE A 544
SER A 539
LEU A 505
PHE A 445
PHE A 480
 None
 1.42A 6dwnB-1zsqA:
undetectable		 6dwnB-1zsqA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS

(Escherichia
coli) 		PF05307
(Bundlin) 		5 ILE A  42
SER A  40
LEU A  84
ASN A  70
ASP A  39
 None
 1.37A 6dwnB-1zwtA:
undetectable		 6dwnB-1zwtA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1l RESTRICTION
ENDONUCLEASE

(Bacillus firmus) 		PF13091
(PLDc_2) 		5 ILE A 304
PHE A 237
PHE A 342
ASP A 236
ILE A 257
 None
 1.47A 6dwnB-2c1lA:
undetectable		 6dwnB-2c1lA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cje DUTPASE

(Leishmania
major) 		PF08761
(dUTPase_2) 		5 ASN A 183
LEU A  24
ASN A  25
ASP A  79
ILE A 157
 DUN  A1266 (-3.1A)
DUN  A1266 (-4.4A)
DUN  A1266 (-3.7A)
MG  A1268 ( 3.0A)
None
 1.45A 6dwnB-2cjeA:
undetectable		 6dwnB-2cjeA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fea 2-HYDROXY-3-KETO-5-M
ETHYLTHIOPENTENYL-1-
PHOSPHATE
PHOSPHATASE

(Bacillus
subtilis) 		PF12710
(HAD) 		5 ILE A  67
SER A  61
PHE A 104
LEU A  72
ASP A 103
 None
 1.49A 6dwnB-2feaA:
undetectable		 6dwnB-2feaA:
20.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hi4 CYTOCHROME P450 1A2

(Homo sapiens) 		PF00067
(p450) 		7 ILE A 117
PHE A 226
ASN A 257
ASP A 313
ASP A 320
ILE A 386
LYS A 500
 None
BHF  A 800 (-3.6A)
None
BHF  A 800 (-3.9A)
BHF  A 800 (-4.0A)
HEM  A 900 (-4.0A)
None
 0.65A 6dwnB-2hi4A:
55.8		 6dwnB-2hi4A:
81.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hi4 CYTOCHROME P450 1A2

(Homo sapiens) 		PF00067
(p450) 		6 ILE A 117
PHE A 226
ASN A 257
PHE A 260
ASP A 320
LYS A 500
 None
BHF  A 800 (-3.6A)
None
BHF  A 800 (-3.6A)
BHF  A 800 (-4.0A)
None
 0.92A 6dwnB-2hi4A:
55.8		 6dwnB-2hi4A:
81.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hi4 CYTOCHROME P450 1A2

(Homo sapiens) 		PF00067
(p450) 		5 PHE A 226
LEU A 219
ASP A 313
ILE A 386
LYS A 500
 BHF  A 800 (-3.6A)
None
BHF  A 800 (-3.9A)
HEM  A 900 (-4.0A)
None
 1.44A 6dwnB-2hi4A:
55.8		 6dwnB-2hi4A:
81.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j89 METHIONINE SULFOXIDE
REDUCTASE A

(Populus
trichocarpa) 		PF01625
(PMSR) 		5 ILE A 159
SER A 131
LEU A 154
ASP A 107
ILE A 133
 None
 1.39A 6dwnB-2j89A:
undetectable		 6dwnB-2j89A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jdx PROTEIN
(L-ARGININE:GLYCINE
AMIDINOTRANSFERASE)

(Homo sapiens) 		no annotation 5 ASN A 361
PHE A 405
LEU A 358
ASN A 399
ILE A 133
 None
 1.48A 6dwnB-2jdxA:
undetectable		 6dwnB-2jdxA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l3f UNCHARACTERIZED
PROTEIN

(Methanosarcina
acetivorans) 		PF03167
(UDG) 		5 ILE A  18
ASN A  39
PHE A  41
ASN A 113
ILE A  49
 None
 1.47A 6dwnB-2l3fA:
undetectable		 6dwnB-2l3fA:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o7q BIFUNCTIONAL
3-DEHYDROQUINATE
DEHYDRATASE/SHIKIMAT
E DEHYDROGENASE

(Arabidopsis
thaliana) 		PF01487
(DHquinase_I)
PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		5 ILE A 267
SER A 212
LEU A  95
ASP A 186
ILE A 232
 None
 1.25A 6dwnB-2o7qA:
undetectable		 6dwnB-2o7qA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odp COMPLEMENT C2

(Homo sapiens) 		PF00089
(Trypsin)
PF00092
(VWA) 		5 SER A 256
LEU A 406
PHE A 278
ASP A 240
ILE A 252
 None
None
None
MG  A 901 ( 3.9A)
None
 1.49A 6dwnB-2odpA:
undetectable		 6dwnB-2odpA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qby CELL DIVISION
CONTROL PROTEIN 6
HOMOLOG 1

(Sulfolobus
solfataricus) 		PF09079
(Cdc6_C)
PF13401
(AAA_22) 		5 ILE A 159
PHE A 151
ASN A 156
ASP A  99
ILE A  93
 None
 1.30A 6dwnB-2qbyA:
undetectable		 6dwnB-2qbyA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rch CYTOCHROME P450 74A

(Arabidopsis
thaliana) 		PF00067
(p450) 		5 ILE A 497
PHE A 495
LEU A 197
PHE A 209
PHE A 484
 None
 1.24A 6dwnB-2rchA:
28.4		 6dwnB-2rchA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yky BETA-TRANSAMINASE

(Mesorhizobium
sp. LUK) 		PF00202
(Aminotran_3) 		5 LEU A 352
ASN A 351
PHE A 348
ASP A 423
PHE A  85
 None
 1.17A 6dwnB-2ykyA:
undetectable		 6dwnB-2ykyA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z63 TOLL-LIKE RECEPTOR
4, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF11921
(DUF3439)
PF13516
(LRR_6)
PF13855
(LRR_8) 		5 LEU A 532
ASN A 530
ASP A 502
PHE A 516
ILE A 454
 None
 1.25A 6dwnB-2z63A:
undetectable		 6dwnB-2z63A:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zzw ABC TRANSPORTER,
SOLUTE-BINDING
PROTEIN

(Thermus
thermophilus) 		PF03480
(DctP) 		5 ILE A 159
LEU A 226
ASN A 223
PHE A 217
PHE A  98
 None
None
None
LAC  A 401 ( 4.6A)
LAC  A 401 (-4.0A)
 1.42A 6dwnB-2zzwA:
undetectable		 6dwnB-2zzwA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahi XYLULOSE
5-PHOSPHATE/FRUCTOSE
6-PHOSPHATE
PHOSPHOKETOLASE

(Bifidobacterium
breve) 		PF03894
(XFP)
PF09363
(XFP_C)
PF09364
(XFP_N) 		5 ILE A 575
SER A 560
PHE A 577
ASP A 715
PHE A 707
 None
 1.50A 6dwnB-3ahiA:
undetectable		 6dwnB-3ahiA:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bzm MENAQUINONE-SPECIFIC
ISOCHORISMATE
SYNTHASE

(Escherichia
coli) 		PF00425
(Chorismate_bind) 		5 ILE A  70
LEU A  67
PHE A 143
ASP A 136
ILE A  25
 None
 1.43A 6dwnB-3bzmA:
undetectable		 6dwnB-3bzmA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cij UPF0100 PROTEIN
AF_0094

(Archaeoglobus
fulgidus) 		PF13531
(SBP_bac_11) 		5 ILE A 205
SER A 184
LEU A 272
ASN A 151
ILE A 212
 None
 1.34A 6dwnB-3cijA:
undetectable		 6dwnB-3cijA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3db2 PUTATIVE
NADPH-DEPENDENT
OXIDOREDUCTASE

(Desulfitobacterium
hafniense) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		5 ILE A  98
LEU A 334
ASP A 109
ASP A 103
ILE A  82
 None
 1.44A 6dwnB-3db2A:
undetectable		 6dwnB-3db2A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ec2 DNA REPLICATION
PROTEIN DNAC

(Aquifex
aeolicus) 		PF01695
(IstB_IS21) 		5 ILE A 211
LEU A  82
ASN A 215
ASP A 148
ILE A 163
 None
None
None
MG  A 300 (-3.7A)
None
 1.49A 6dwnB-3ec2A:
undetectable		 6dwnB-3ec2A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fn5 SORTASE A

(Streptococcus
pyogenes) 		PF04203
(Sortase) 		5 ASN A 241
PHE A 240
LEU A 237
ASP A 171
ILE A 109
 None
 1.34A 6dwnB-3fn5A:
undetectable		 6dwnB-3fn5A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h14 AMINOTRANSFERASE,
CLASSES I AND II

(Ruegeria
pomeroyi) 		PF00155
(Aminotran_1_2) 		5 ILE A 198
PHE A 108
LEU A 106
ASP A 200
ILE A 120
 None
 1.42A 6dwnB-3h14A:
undetectable		 6dwnB-3h14A:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hh8 METAL ABC
TRANSPORTER
SUBSTRATE-BINDING
LIPOPROTEIN

(Streptococcus
pyogenes) 		PF01297
(ZnuA) 		5 ILE A 277
LEU A 300
ASN A 299
PHE A 211
ILE A 273
 None
 1.44A 6dwnB-3hh8A:
undetectable		 6dwnB-3hh8A:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ikb UNCHARACTERIZED
CONSERVED PROTEIN

(Streptococcus
mutans) 		PF03167
(UDG) 		5 ILE A  11
PHE A 104
ASN A  17
PHE A  20
ILE A 112
 None
 1.02A 6dwnB-3ikbA:
undetectable		 6dwnB-3ikbA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ktc XYLOSE ISOMERASE

(Pectobacterium
atrosepticum) 		PF01261
(AP_endonuc_2) 		5 ILE A 219
LEU A 258
PHE A 254
ASP A 229
ILE A 165
 None
None
None
FE  A 334 (-3.1A)
None
 1.33A 6dwnB-3ktcA:
undetectable		 6dwnB-3ktcA:
13.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pm0 CYTOCHROME P450 1B1

(Homo sapiens) 		PF00067
(p450) 		7 PHE A 231
ASN A 265
PHE A 268
ASP A 326
ASP A 333
ILE A 399
LYS A 512
 BHF  A 800 (-3.4A)
None
BHF  A 800 ( 3.8A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.1A)
HEM  A 900 (-4.0A)
None
 0.81A 6dwnB-3pm0A:
48.1		 6dwnB-3pm0A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pm0 CYTOCHROME P450 1B1

(Homo sapiens) 		PF00067
(p450) 		5 SER A 131
LEU A 224
ASP A 326
ASP A 333
LYS A 512
 BHF  A 800 ( 4.7A)
None
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.1A)
None
 1.43A 6dwnB-3pm0A:
48.1		 6dwnB-3pm0A:
58.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psg PEPSINOGEN

(Sus scrofa) 		PF00026
(Asp)
PF07966
(A1_Propeptide) 		5 ILE A 275
SER A 251
LEU A 221
PHE A 286
ASP A 257
 None
 1.41A 6dwnB-3psgA:
undetectable		 6dwnB-3psgA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r08 MOUSE ANTI-MOUSE
CD3EPSILON ANTIBODY
2C11 LIGHT CHAIN

(Cricetulus
migratorius) 		PF07654
(C1-set)
PF07686
(V-set) 		5 LEU L 175
ASN L 137
PHE L 139
ASP L 170
ASP L 165
 None
 1.44A 6dwnB-3r08L:
undetectable		 6dwnB-3r08L:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ve9 OROTIDINE-5'-PHOSPHA
TE DECARBOXYLASE

(Metallosphaera
sedula) 		PF00215
(OMPdecase) 		5 ILE A 155
PHE A 102
LEU A 103
PHE A 132
ASP A 175
 None
 1.35A 6dwnB-3ve9A:
undetectable		 6dwnB-3ve9A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vtg HIGH CHORIOLYTIC
ENZYME 1

(Oryzias latipes) 		PF01400
(Astacin) 		5 ILE A 152
SER A 150
LEU A 105
ASN A 102
PHE A 107
 None
 1.32A 6dwnB-3vtgA:
undetectable		 6dwnB-3vtgA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zi5 RESTRICTION
ENDONUCLEASE

(Bacillus firmus) 		no annotation 5 ILE A 304
PHE A 237
PHE A 342
ASP A 236
ILE A 257
 None
 1.45A 6dwnB-3zi5A:
undetectable		 6dwnB-3zi5A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b7g CATALASE

(Corynebacterium
glutamicum) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		5 ILE A 140
SER A 212
LEU A 104
PHE A 311
PHE A 108
 None
HEM  A3000 (-3.5A)
None
None
None
 1.37A 6dwnB-4b7gA:
undetectable		 6dwnB-4b7gA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4btp P1

(Pseudomonas
phage phi8) 		no annotation 5 ILE A 289
LEU A 285
PHE A 366
ASP A 191
ILE A 503
 None
 1.39A 6dwnB-4btpA:
undetectable		 6dwnB-4btpA:
6.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bv4 PROTEIN TOLL,
VARIABLE LYMPHOCYTE
RECEPTOR B CHIMERA

(Drosophila
melanogaster;
Eptatretus
burgeri) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		5 SER R 348
LEU R 402
ASN R 400
ASP R 372
PHE R 386
 None
 1.36A 6dwnB-4bv4R:
undetectable		 6dwnB-4bv4R:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4crs SERINE/THREONINE-PRO
TEIN KINASE N2

(Homo sapiens) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		5 ILE A 685
LEU A 723
PHE A 735
PHE A 977
ASP A 978
 None
 1.45A 6dwnB-4crsA:
undetectable		 6dwnB-4crsA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewc PUTATIVE
NUCLEOPROTEIN

(Salmon isavirus) 		no annotation 5 ILE A 387
PHE A 148
LEU A 177
PHE A 143
ILE A 415
 None
 1.16A 6dwnB-4ewcA:
undetectable		 6dwnB-4ewcA:
9.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		5 ILE A 115
ASN A 223
PHE A 224
ASN A 255
ILE A 386
 BHF  A 602 (-4.7A)
None
BHF  A 602 (-3.3A)
None
HEM  A 601 (-3.6A)
 1.34A 6dwnB-4i8vA:
61.1		 6dwnB-4i8vA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		8 ILE A 115
SER A 122
ASN A 222
LEU A 254
ASN A 255
PHE A 258
ASP A 313
PHE A 319
 BHF  A 602 (-4.7A)
HEM  A 601 (-3.4A)
BHF  A 602 ( 3.8A)
None
None
BHF  A 602 ( 3.9A)
BHF  A 602 (-3.7A)
BHF  A 602 ( 4.7A)
 0.90A 6dwnB-4i8vA:
61.1		 6dwnB-4i8vA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		9 ILE A 115
SER A 122
ASN A 222
PHE A 224
ASN A 255
PHE A 258
ASP A 313
PHE A 319
ILE A 386
 BHF  A 602 (-4.7A)
HEM  A 601 (-3.4A)
BHF  A 602 ( 3.8A)
BHF  A 602 (-3.3A)
None
BHF  A 602 ( 3.9A)
BHF  A 602 (-3.7A)
BHF  A 602 ( 4.7A)
HEM  A 601 (-3.6A)
 0.75A 6dwnB-4i8vA:
61.1		 6dwnB-4i8vA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		9 ILE A 115
SER A 122
PHE A 224
ASN A 255
ASP A 313
PHE A 319
ASP A 320
ILE A 386
LYS A 499
 BHF  A 602 (-4.7A)
HEM  A 601 (-3.4A)
BHF  A 602 (-3.3A)
None
BHF  A 602 (-3.7A)
BHF  A 602 ( 4.7A)
BHF  A 602 (-3.7A)
HEM  A 601 (-3.6A)
None
 0.44A 6dwnB-4i8vA:
61.1		 6dwnB-4i8vA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		9 ILE A 115
SER A 122
PHE A 224
ASN A 255
PHE A 258
ASP A 313
PHE A 319
ASP A 320
ILE A 386
 BHF  A 602 (-4.7A)
HEM  A 601 (-3.4A)
BHF  A 602 (-3.3A)
None
BHF  A 602 ( 3.9A)
BHF  A 602 (-3.7A)
BHF  A 602 ( 4.7A)
BHF  A 602 (-3.7A)
HEM  A 601 (-3.6A)
 0.57A 6dwnB-4i8vA:
61.1		 6dwnB-4i8vA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		5 SER A 122
LEU A 217
ASP A 313
ASP A 320
LYS A 499
 HEM  A 601 (-3.4A)
None
BHF  A 602 (-3.7A)
BHF  A 602 (-3.7A)
None
 1.35A 6dwnB-4i8vA:
61.1		 6dwnB-4i8vA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		5 SER A 122
PHE A 315
ASP A 313
ASP A 320
LYS A 499
 HEM  A 601 (-3.4A)
None
BHF  A 602 (-3.7A)
BHF  A 602 (-3.7A)
None
 1.44A 6dwnB-4i8vA:
61.1		 6dwnB-4i8vA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifr 2-AMINO-3-CARBOXYMUC
ONATE 6-SEMIALDEHYDE
DECARBOXYLASE

(Pseudomonas
fluorescens) 		PF04909
(Amidohydro_2) 		5 ILE A 224
LEU A 118
PHE A 330
ASP A 268
ILE A 206
 None
 1.22A 6dwnB-4ifrA:
undetectable		 6dwnB-4ifrA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igg CATENIN ALPHA-1

(Homo sapiens) 		PF01044
(Vinculin) 		5 LEU A 364
ASN A 365
PHE A 301
ASP A 292
ILE A 792
 None
 1.45A 6dwnB-4iggA:
undetectable		 6dwnB-4iggA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A

(Mus musculus) 		PF13516
(LRR_6) 		5 LEU A 214
PHE A 159
ASP A 183
PHE A 199
ASP A 198
 None
 1.45A 6dwnB-4k17A:
undetectable		 6dwnB-4k17A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kjy LEUKOCYTE SURFACE
ANTIGEN CD47
HIGH-AFFINITY SIRPA
VARIANT FD6

(Homo sapiens;
Homo sapiens) 		PF08204
(V-set_CD47)
PF07686
(V-set) 		5 ILE B  36
LEU B  48
PHE B  39
ASP B 100
LYS A  39
 None
 1.32A 6dwnB-4kjyB:
undetectable		 6dwnB-4kjyB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kt1 LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4

(Homo sapiens) 		PF01462
(LRRNT)
PF13516
(LRR_6)
PF13855
(LRR_8) 		5 SER A 371
LEU A 425
ASN A 423
ASP A 395
PHE A 409
 None
 1.38A 6dwnB-4kt1A:
undetectable		 6dwnB-4kt1A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lq1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB

(Escherichia
coli) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		5 ILE A 289
ASN A 389
LEU A 305
ASN A 290
ILE A 322
 None
 1.29A 6dwnB-4lq1A:
undetectable		 6dwnB-4lq1A:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lxr PROTEIN TOLL

(Drosophila
melanogaster) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13306
(LRR_5)
PF13855
(LRR_8) 		5 SER A 348
LEU A 402
ASN A 400
ASP A 372
PHE A 386
 None
 1.37A 6dwnB-4lxrA:
undetectable		 6dwnB-4lxrA:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyp EXO-BETA-1,4-MANNOSI
DASE

(Rhizomucor
miehei) 		no annotation 5 ILE A 218
SER A 228
ASN A 166
PHE A 123
ILE A 249
 None
 1.35A 6dwnB-4lypA:
undetectable		 6dwnB-4lypA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4msx PRE-MRNA-SPLICING
FACTOR SAD1

(Saccharomyces
cerevisiae) 		PF00443
(UCH)
PF02148
(zf-UBP) 		5 ILE A 200
LEU A 193
PHE A 215
PHE A 235
ILE A 421
 None
 1.49A 6dwnB-4msxA:
undetectable		 6dwnB-4msxA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mup AMIDOHYDROLASE

(Agrobacterium
fabrum) 		PF04909
(Amidohydro_2) 		5 ILE A  96
LEU A  81
ASN A  77
ASP A  98
ILE A 119
 None
 1.44A 6dwnB-4mupA:
undetectable		 6dwnB-4mupA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qtu PUTATIVE
METHYLTRANSFERASE
BUD23

(Saccharomyces
cerevisiae) 		PF08241
(Methyltransf_11) 		5 ILE B 117
LEU B 197
PHE B 154
ASP B  53
PHE B 140
 SAM  B 301 (-4.2A)
None
None
SAM  B 301 ( 4.6A)
None
 1.30A 6dwnB-4qtuB:
undetectable		 6dwnB-4qtuB:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore) 		5 ILE A1780
ASN A1700
LEU A1698
ASN A1727
ASP A1731
 None
 1.15A 6dwnB-4r04A:
undetectable		 6dwnB-4r04A:
4.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rye D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE

(Mycobacterium
tuberculosis) 		PF00768
(Peptidase_S11) 		5 SER A  87
ASN A 190
ASP A  84
ASP A  81
LYS A 149
 None
 1.33A 6dwnB-4ryeA:
undetectable		 6dwnB-4ryeA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wi0 CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B
CELLULOSOMAL
SCAFFOLDIN

(Acetivibrio
cellulolyticus;
Acetivibrio
cellulolyticus) 		PF00963
(Cohesin)
PF13620
(CarboxypepD_reg) 		5 SER A  94
PHE B 144
ASN A  90
ASP B 169
ILE A  77
 None
None
None
CA  B 202 (-2.2A)
None
 1.50A 6dwnB-4wi0A:
undetectable		 6dwnB-4wi0A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c16 MYOTUBULARIN-RELATED
PROTEIN 1

(Homo sapiens) 		PF02893
(GRAM)
PF06602
(Myotub-related) 		5 ILE A 565
SER A 560
LEU A 526
PHE A 466
PHE A 501
 None
 1.44A 6dwnB-5c16A:
undetectable		 6dwnB-5c16A:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2c FORM II RUBISCO

(Gallionella) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		5 ILE A 164
SER A 368
LEU A 169
ASP A 263
ILE A 366
 KCX  A 191 ( 4.1A)
KCX  A 191 ( 4.1A)
None
None
None
 1.23A 6dwnB-5c2cA:
undetectable		 6dwnB-5c2cA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dl7 PORIN

(Acinetobacter
baumannii) 		PF03573
(OprD) 		5 ILE A 170
SER A 286
ASN A 380
PHE A 388
ASN A 171
 None
 1.27A 6dwnB-5dl7A:
undetectable		 6dwnB-5dl7A:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5edv E3 UBIQUITIN-PROTEIN
LIGASE RNF31

(Homo sapiens) 		PF01485
(IBR) 		5 ILE A 739
PHE A 762
LEU A 769
PHE A 730
ASP A 741
 None
 1.40A 6dwnB-5edvA:
undetectable		 6dwnB-5edvA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f3q PUTATIVE
UNCHARACTERIZED
PROTEIN

(Entamoeba
histolytica) 		no annotation 5 ILE A  21
SER A 187
LEU A 101
PHE A 177
ASP A 146
 None
None
None
None
SO4  A 201 ( 4.4A)
 1.16A 6dwnB-5f3qA:
undetectable		 6dwnB-5f3qA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gr8 LEUCINE-RICH REPEAT
RECEPTOR-LIKE
PROTEIN KINASE PEPR1

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		5 PHE A 710
LEU A 735
ASN A 732
PHE A 729
ILE A 642
 None
 1.35A 6dwnB-5gr8A:
undetectable		 6dwnB-5gr8A:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hgc SERPIN

(Taeniopygia
guttata) 		PF00079
(Serpin) 		5 ASN A  35
PHE A  38
PHE A  87
PHE A 101
ILE A 304
 None
 1.34A 6dwnB-5hgcA:
undetectable		 6dwnB-5hgcA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxs SODIUM,CALCIUM
EXCHANGER

(Methanocaldococcus
jannaschii) 		PF01699
(Na_Ca_ex) 		5 ILE A 234
SER A 268
LEU A 139
ASP A 240
ILE A  82
 None
None
None
SR  A 401 ( 4.7A)
None
 1.29A 6dwnB-5hxsA:
undetectable		 6dwnB-5hxsA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzr SNF2-FAMILY ATP
DEPENDENT CHROMATIN
REMODELING FACTOR
LIKE PROTEIN

(Thermothelomyces
thermophila) 		PF00176
(SNF2_N)
PF00271
(Helicase_C)
PF14619
(SnAC) 		5 ILE A 998
SER A 969
ASP A 623
ILE A1007
LYS A 631
 None
 1.28A 6dwnB-5hzrA:
undetectable		 6dwnB-5hzrA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE GAMMA
SUBUNIT

(Aromatoleum
aromaticum) 		PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		5 ILE B  72
SER B 503
LEU B  67
ASP B  14
PHE B  48
 None
 1.35A 6dwnB-5l9wB:
undetectable		 6dwnB-5l9wB:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lkz HISTONE
ACETYLTRANSFERASE
P300,HISTONE
ACETYLTRANSFERASE
P300

(Homo sapiens) 		PF00439
(Bromodomain)
PF06001
(DUF902)
PF08214
(HAT_KAT11) 		5 ILE A1417
PHE A1374
PHE A1448
ASP A1399
ILE A1395
 None
None
None
COO  A1705 (-4.2A)
None
 1.40A 6dwnB-5lkzA:
undetectable		 6dwnB-5lkzA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o6v ENVELOPE PROTEIN

(Tick-borne
encephalitis
virus) 		no annotation 5 ILE A 358
SER A   1
PHE A  11
ASP A  42
ASP A  10
 None
 1.38A 6dwnB-5o6vA:
undetectable		 6dwnB-5o6vA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7g CREB-BINDING PROTEIN

(Mus musculus) 		PF00439
(Bromodomain)
PF00569
(ZZ)
PF06001
(DUF902)
PF08214
(HAT_KAT11) 		5 ILE A1454
PHE A1411
PHE A1485
ASP A1436
ILE A1432
 None
 1.41A 6dwnB-5u7gA:
undetectable		 6dwnB-5u7gA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xb7 BETA-GALACTOSIDASE

(Bifidobacterium
animalis) 		no annotation 5 SER A 337
PHE A 441
ASN A 444
ASP A 438
ILE A 292
 None
GOL  A 803 (-4.7A)
GOL  A 803 (-2.9A)
None
None
 1.43A 6dwnB-5xb7A:
undetectable		 6dwnB-5xb7A:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xb7 BETA-GALACTOSIDASE

(Bifidobacterium
animalis) 		no annotation 5 SER A 337
PHE A 441
LEU A 443
ASN A 444
ILE A 292
 None
GOL  A 803 (-4.7A)
None
GOL  A 803 (-2.9A)
None
 1.40A 6dwnB-5xb7A:
undetectable		 6dwnB-5xb7A:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bac ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Neisseria
gonorrhoeae) 		no annotation 5 ILE A  29
PHE A   5
PHE A  47
ASP A  25
ILE A  95
 None
 1.43A 6dwnB-6bacA:
undetectable		 6dwnB-6bacA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE

(Plasmodium
vivax) 		no annotation 5 ILE A 296
ASN A 428
ASN A 300
ILE A 189
LYS A 394
 None
 1.39A 6dwnB-6bpcA:
undetectable		 6dwnB-6bpcA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT
N-ALPHA-ACETYLTRANSF
ERASE 10

(Homo sapiens;
Homo sapiens) 		no annotation
no annotation 		5 SER A 121
PHE A 523
ASP A 524
ILE A 125
LYS B  29
 None
 1.39A 6dwnB-6c9mA:
undetectable		 6dwnB-6c9mA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d04 RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE

(Plasmodium
vivax) 		no annotation 5 ILE E 296
ASN E 428
ASN E 300
ILE E 189
LYS E 394
 None
 1.27A 6dwnB-6d04E:
undetectable		 6dwnB-6d04E:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6et0 PQSB

(Pseudomonas
aeruginosa) 		no annotation 5 ILE B 178
PHE B 266
LEU B 196
PHE B 263
ASP B 264
 None
 1.45A 6dwnB-6et0B:
undetectable		 6dwnB-6et0B:
21.59