SIMILAR PATTERNS OF AMINO ACIDS FOR 6DWD_D_GLYD713_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6y METHYL-COENZYME M
REDUCTASE SUBUNIT
GAMMA

(Methanosarcina
barkeri) 		PF02240
(MCR_gamma) 		3 ARG C3044
HIS C3043
ARG C3082
 None
 1.03A 6dwdD-1e6yC:
0.0		 6dwdD-1e6yC:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gpm GMP SYNTHETASE

(Escherichia
coli) 		PF00117
(GATase)
PF00958
(GMP_synt_C)
PF02540
(NAD_synthase) 		3 ARG A 400
HIS A 401
ARG A 436
 None
 1.15A 6dwdD-1gpmA:
0.0		 6dwdD-1gpmA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2d ATP SULFURYLASE

(Penicillium
chrysogenum) 		PF01583
(APS_kinase)
PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		3 ARG A 365
HIS A 371
ARG A 386
 None
 1.05A 6dwdD-1i2dA:
0.0		 6dwdD-1i2dA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1luj CATENIN BETA-1

(Homo sapiens) 		PF00514
(Arm) 		3 ARG A 515
HIS A 578
ARG A 582
 None
 1.01A 6dwdD-1lujA:
0.0		 6dwdD-1lujA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qlb FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT

(Wolinella
succinogenes) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		3 ARG A 301
HIS A 369
ARG A 404
 FUM  A1657 (-2.6A)
FUM  A1657 ( 3.7A)
FUM  A1657 ( 2.7A)
 0.89A 6dwdD-1qlbA:
0.0		 6dwdD-1qlbA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sql DIHYDRONEOPTERIN
ALDOLASE

(Arabidopsis
thaliana) 		PF02152
(FolB) 		3 ARG A  69
HIS A  15
ARG A  22
 None
 1.17A 6dwdD-1sqlA:
0.0		 6dwdD-1sqlA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmi S-ADENOSYLMETHIONINE
DECARBOXYLASE
PROENZYME, ADOMETDC,
SAMDC

(Thermotoga
maritima) 		PF02675
(AdoMet_dc) 		3 ARG A 112
HIS A 110
ARG A 114
 None
 1.14A 6dwdD-1tmiA:
0.0		 6dwdD-1tmiA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yiu ITCHY E3 UBIQUITIN
PROTEIN LIGASE

(Mus musculus) 		PF00397
(WW) 		3 ARG A  28
HIS A  25
ARG A  13
 None
 1.12A 6dwdD-1yiuA:
undetectable		 6dwdD-1yiuA:
5.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yqd SINAPYL ALCOHOL
DEHYDROGENASE

(Populus
tremuloides) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 ARG A  32
HIS A   9
ARG A  33
 None
 1.14A 6dwdD-1yqdA:
0.0		 6dwdD-1yqdA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yyh NOTCH 1, ANKYRIN
DOMAIN

(Homo sapiens) 		PF12796
(Ank_2) 		3 ARG A  66
HIS A  62
ARG A  91
 None
 1.18A 6dwdD-1yyhA:
undetectable		 6dwdD-1yyhA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a33 HYPOTHETICAL PROTEIN

(Arabidopsis
thaliana) 		PF03641
(Lysine_decarbox) 		3 ARG A  15
HIS A  71
ARG A  94
 None
 0.97A 6dwdD-2a33A:
undetectable		 6dwdD-2a33A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b4v RNA EDITING COMPLEX
PROTEIN MP57

(Trypanosoma
brucei) 		PF01909
(NTP_transf_2)
PF03828
(PAP_assoc) 		3 ARG A 293
HIS A 286
ARG A 282
 None
 1.16A 6dwdD-2b4vA:
undetectable		 6dwdD-2b4vA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b8t THYMIDINE KINASE

(Ureaplasma
parvum) 		PF00265
(TK) 		3 ARG A 192
HIS A 195
ARG A 200
 None
 1.19A 6dwdD-2b8tA:
undetectable		 6dwdD-2b8tA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bwm PSATHYRELLA VELUTINA
LECTIN PVL

(Lacrymaria
velutina) 		PF13517
(VCBS) 		3 ARG A  55
HIS A  59
ARG A  61
 None
SNG  A1403 (-3.7A)
None
 1.14A 6dwdD-2bwmA:
undetectable		 6dwdD-2bwmA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bwm PSATHYRELLA VELUTINA
LECTIN PVL

(Lacrymaria
velutina) 		PF13517
(VCBS) 		3 ARG A 112
HIS A 116
ARG A 118
 None
SNG  A1404 (-3.9A)
None
 1.11A 6dwdD-2bwmA:
undetectable		 6dwdD-2bwmA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bwm PSATHYRELLA VELUTINA
LECTIN PVL

(Lacrymaria
velutina) 		PF13517
(VCBS) 		3 ARG A 167
HIS A 171
ARG A 173
 None
SNG  A1405 (-3.9A)
None
 1.12A 6dwdD-2bwmA:
undetectable		 6dwdD-2bwmA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bwm PSATHYRELLA VELUTINA
LECTIN PVL

(Lacrymaria
velutina) 		PF13517
(VCBS) 		3 ARG A 278
HIS A 282
ARG A 284
 None
SNG  A1407 (-3.9A)
None
 1.09A 6dwdD-2bwmA:
undetectable		 6dwdD-2bwmA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bwm PSATHYRELLA VELUTINA
LECTIN PVL

(Lacrymaria
velutina) 		PF13517
(VCBS) 		3 ARG A 333
HIS A 337
ARG A 339
 None
 1.14A 6dwdD-2bwmA:
undetectable		 6dwdD-2bwmA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cof PROTEIN KIAA1914

(Homo sapiens) 		PF00169
(PH) 		3 ARG A  30
HIS A  35
ARG A  42
 None
 1.17A 6dwdD-2cofA:
undetectable		 6dwdD-2cofA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2drw D-AMINO ACID AMIDASE

(Ochrobactrum
anthropi) 		PF00144
(Beta-lactamase) 		3 ARG A  18
HIS A  15
ARG A 353
 None
 0.92A 6dwdD-2drwA:
undetectable		 6dwdD-2drwA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ep7 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Aquifex
aeolicus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 ARG A  19
HIS A  51
ARG A  12
 None
 1.18A 6dwdD-2ep7A:
undetectable		 6dwdD-2ep7A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eq9 PYRUVATE
DEHYDROGENASE
COMPLEX,
DIHYDROLIPOAMIDE
DEHYDROGENASE E3
COMPONENT

(Thermus
thermophilus) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		3 ARG A 327
HIS A  23
ARG A  27
 None
 0.87A 6dwdD-2eq9A:
undetectable		 6dwdD-2eq9A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mzr PROTEIN HRB1

(Saccharomyces
cerevisiae) 		PF00076
(RRM_1) 		3 ARG A 196
HIS A 198
ARG A 200
 None
 1.14A 6dwdD-2mzrA:
undetectable		 6dwdD-2mzrA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oqk PUTATIVE TRANSLATION
INITIATION FACTOR
EIF-1A

(Cryptosporidium
parvum) 		PF01176
(eIF-1a) 		3 ARG A  46
HIS A  60
ARG A  82
 SO4  A 201 (-3.9A)
SO4  A 201 (-4.4A)
SO4  A 201 (-3.0A)
 0.67A 6dwdD-2oqkA:
undetectable		 6dwdD-2oqkA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qua EXTRACELLULAR LIPASE

(Serratia
marcescens) 		no annotation 3 ARG A 147
HIS A  30
ARG A 141
 None
 1.17A 6dwdD-2quaA:
undetectable		 6dwdD-2quaA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5e GDNF FAMILY RECEPTOR
ALPHA-1

(Rattus
norvegicus) 		PF02351
(GDNF) 		3 ARG A 190
HIS A 193
ARG A 197
 SCR  A1350 (-4.3A)
None
SCR  A1350 ( 3.1A)
 1.14A 6dwdD-2v5eA:
undetectable		 6dwdD-2v5eA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vif SUPPRESSOR OF
CYTOKINE SIGNALLING
6

(Homo sapiens) 		PF00017
(SH2) 		3 ARG A 432
HIS A 430
ARG A 409
 None
 1.06A 6dwdD-2vifA:
undetectable		 6dwdD-2vifA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xt6 2-OXOGLUTARATE
DECARBOXYLASE

(Mycolicibacterium
smegmatis) 		PF00198
(2-oxoacid_dh)
PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF16870
(OxoGdeHyase_C) 		3 ARG A 911
HIS A 912
ARG A 867
 None
 0.79A 6dwdD-2xt6A:
undetectable		 6dwdD-2xt6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b5q PUTATIVE SULFATASE
YIDJ

(Bacteroides
thetaiotaomicron) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		3 ARG A  83
HIS A  78
ARG A 387
 None
 1.04A 6dwdD-3b5qA:
undetectable		 6dwdD-3b5qA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b5q PUTATIVE SULFATASE
YIDJ

(Bacteroides
thetaiotaomicron) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		3 ARG A 434
HIS A 398
ARG A 449
 None
 1.15A 6dwdD-3b5qA:
undetectable		 6dwdD-3b5qA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cps GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Cryptosporidium
parvum) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 ARG A  34
HIS A  67
ARG A  27
 None
 1.19A 6dwdD-3cpsA:
undetectable		 6dwdD-3cpsA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzc UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Vibrio cholerae) 		PF02350
(Epimerase_2) 		3 ARG A  11
HIS A  40
ARG A  41
 None
 1.16A 6dwdD-3dzcA:
undetectable		 6dwdD-3dzcA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzd TRANSCRIPTIONAL
REGULATOR (NTRC
FAMILY)

(Aquifex
aeolicus) 		PF00072
(Response_reg)
PF00158
(Sigma54_activat) 		3 ARG A 171
HIS A 174
ARG A 175
 None
 0.93A 6dwdD-3dzdA:
undetectable		 6dwdD-3dzdA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fub GDNF FAMILY RECEPTOR
ALPHA-1

(Rattus
norvegicus) 		PF02351
(GDNF) 		3 ARG A 190
HIS A 193
ARG A 197
 None
 0.84A 6dwdD-3fubA:
undetectable		 6dwdD-3fubA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gd7 FUSION COMPLEX OF
CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR, RESIDUES
1193-1427 AND
MALTOSE/MALTODEXTRIN
IMPORT ATP-BINDING
PROTEIN MALK,
RESIDUES 219-371

(Escherichia
coli;
Homo sapiens) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		3 ARG A1560
HIS A1575
ARG A1573
 None
 1.08A 6dwdD-3gd7A:
undetectable		 6dwdD-3gd7A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ

(Bacillus
subtilis) 		PF01497
(Peripla_BP_2) 		3 ARG A 236
HIS A 214
ARG A 192
 None
PO4  A 304 (-3.9A)
PO4  A 304 (-3.0A)
 0.70A 6dwdD-3gfvA:
undetectable		 6dwdD-3gfvA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ifq PLAKOGLOBIN

(Homo sapiens) 		PF00514
(Arm) 		3 ARG A 506
HIS A 568
ARG A 572
 None
 1.09A 6dwdD-3ifqA:
undetectable		 6dwdD-3ifqA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kul EPHRIN TYPE-A
RECEPTOR 8

(Homo sapiens) 		PF07714
(Pkinase_Tyr)
PF14575
(EphA2_TM) 		3 ARG A 882
HIS A 876
ARG A 856
 None
 1.19A 6dwdD-3kulA:
undetectable		 6dwdD-3kulA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l0d GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Bartonella
henselae) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 ARG A  19
HIS A  53
ARG A  12
 None
 1.14A 6dwdD-3l0dA:
undetectable		 6dwdD-3l0dA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN

(Marinobacter
hydrocarbonoclasticus) 		PF04073
(tRNA_edit)
PF08668
(HDOD) 		3 ARG A 356
HIS A 314
ARG A 400
 None
 1.01A 6dwdD-3memA:
3.8		 6dwdD-3memA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT
6-PHOSPHOFRUCTO-1-KI
NASE BETA-SUBUNIT

(Komagataella
pastoris;
Komagataella
pastoris) 		PF00365
(PFK)
PF00365
(PFK) 		3 ARG A 487
HIS B 466
ARG A 396
 SO4  A 999 (-3.4A)
SO4  A 999 (-3.6A)
SO4  A 999 (-2.9A)
 1.18A 6dwdD-3opyA:
undetectable		 6dwdD-3opyA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT
6-PHOSPHOFRUCTO-1-KI
NASE BETA-SUBUNIT

(Komagataella
pastoris;
Komagataella
pastoris) 		PF00365
(PFK)
PF00365
(PFK) 		3 ARG B 460
HIS A 493
ARG B 368
 SO4  B 943 (-3.7A)
SO4  B 943 (-4.2A)
SO4  B 943 (-2.6A)
 0.85A 6dwdD-3opyB:
undetectable		 6dwdD-3opyB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3org CMCLC

(Cyanidioschyzon
merolae) 		PF00654
(Voltage_CLC) 		3 ARG A 491
HIS A 492
ARG A 317
 None
 1.12A 6dwdD-3orgA:
undetectable		 6dwdD-3orgA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8t ASNS-LIKE
ASPARAGINYL-TRNA
SYNTHETASE RELATED
PROTEIN

(Pyrococcus
abyssi) 		PF00152
(tRNA-synt_2) 		3 ARG A  99
HIS A 110
ARG A 267
 None
 1.16A 6dwdD-3p8tA:
undetectable		 6dwdD-3p8tA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pym GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
3

(Saccharomyces
cerevisiae) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 ARG A  18
HIS A  51
ARG A  11
 None
 1.16A 6dwdD-3pymA:
undetectable		 6dwdD-3pymA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sxs CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 ARG A 656
HIS A 650
ARG A 630
 None
 1.17A 6dwdD-3sxsA:
undetectable		 6dwdD-3sxsA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujg SERINE/THREONINE-PRO
TEIN KINASE SRK2E

(Arabidopsis
thaliana) 		PF00069
(Pkinase) 		3 ARG A 155
HIS A  74
ARG A  79
 None
 1.15A 6dwdD-3ujgA:
undetectable		 6dwdD-3ujgA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhr MULTIFUNCTIONAL
2-OXOGLUTARATE
METABOLISM ENZYME

(Mycolicibacterium
smegmatis) 		PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF16870
(OxoGdeHyase_C) 		3 ARG A 911
HIS A 912
ARG A 867
 None
 0.79A 6dwdD-3zhrA:
undetectable		 6dwdD-3zhrA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aio LIMIT DEXTRINASE

(Hordeum vulgare) 		PF02922
(CBM_48)
PF11852
(DUF3372) 		3 ARG A 276
HIS A 267
ARG A 262
 None
 0.97A 6dwdD-4aioA:
undetectable		 6dwdD-4aioA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aq2 HOMOGENTISATE
1,2-DIOXYGENASE

(Pseudomonas
putida) 		PF04209
(HgmA) 		3 ARG A  81
HIS A 249
ARG A 142
 None
 0.93A 6dwdD-4aq2A:
undetectable		 6dwdD-4aq2A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci2 PROTEIN CEREBLON

(Gallus gallus) 		PF02190
(LON_substr_bdg)
PF03226
(Yippee-Mis18) 		3 ARG B  71
HIS B  69
ARG B 119
 None
 1.10A 6dwdD-4ci2B:
undetectable		 6dwdD-4ci2B:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cyl EFF-1A

(Caenorhabditis
elegans) 		PF14884
(EFF-AFF) 		3 ARG A 446
HIS A  49
ARG A  84
 None
 0.99A 6dwdD-4cylA:
undetectable		 6dwdD-4cylA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdd RNA-BINDING PROTEIN
FUS

(Homo sapiens) 		no annotation 3 ARG B 518
HIS B 517
ARG B 521
 None
 1.09A 6dwdD-4fddB:
undetectable		 6dwdD-4fddB:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fff LEVAN
FRUCTOTRANSFERASE

(Paenarthrobacter
ureafaciens) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		3 ARG A  57
HIS A 190
ARG A 313
 None
 0.91A 6dwdD-4fffA:
undetectable		 6dwdD-4fffA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fq3 FUSION (INVOLVED IN
T(12
16) IN MALIGNANT
LIPOSARCOMA)

(Homo sapiens) 		no annotation 3 ARG B 518
HIS B 517
ARG B 521
 None
 1.07A 6dwdD-4fq3B:
undetectable		 6dwdD-4fq3B:
5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j7h EVAA 2,3-DEHYDRATASE

(Amycolatopsis
orientalis) 		PF03559
(Hexose_dehydrat) 		3 ARG A 181
HIS A  18
ARG A  23
 None
 1.06A 6dwdD-4j7hA:
undetectable		 6dwdD-4j7hA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jcc IRON-COMPOUND ABC
TRANSPORTER,
IRON-COMPOUND-BINDIN
G PROTEIN

(Streptococcus
pneumoniae) 		PF01497
(Peripla_BP_2) 		3 ARG A 260
HIS A 238
ARG A 216
 None
 0.93A 6dwdD-4jccA:
undetectable		 6dwdD-4jccA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ldy AUXIN RESPONSE
FACTOR 1

(Arabidopsis
thaliana) 		PF02362
(B3)
PF06507
(Auxin_resp) 		3 ARG A 224
HIS A 225
ARG A 227
 None
 1.03A 6dwdD-4ldyA:
undetectable		 6dwdD-4ldyA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mju NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ARG A 107
HIS A 459
ARG A 428
 None
 1.17A 6dwdD-4mjuA:
undetectable		 6dwdD-4mjuA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9j SERINE/THREONINE-PRO
TEIN KINASE PLK4

(Homo sapiens) 		no annotation 3 ARG A 697
HIS A 597
ARG A 598
 None
 0.93A 6dwdD-4n9jA:
undetectable		 6dwdD-4n9jA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nru RNA DEPENDENT RNA
POLYMERASE

(Norwalk virus) 		PF00680
(RdRP_1) 		3 ARG A 231
HIS A 232
ARG A 216
 None
 1.07A 6dwdD-4nruA:
undetectable		 6dwdD-4nruA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o3m BLOOM SYNDROME
PROTEIN

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF00570
(HRDC)
PF09382
(RQC)
PF16124
(RecQ_Zn_bind) 		3 ARG A 859
HIS A 860
ARG A1038
 EDO  A1304 (-3.6A)
None
None
 1.08A 6dwdD-4o3mA:
undetectable		 6dwdD-4o3mA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o59 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Bos taurus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 ARG O  17
HIS O  50
ARG O  10
 None
 1.17A 6dwdD-4o59O:
undetectable		 6dwdD-4o59O:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p17 RABGAP/TBC PROTEIN

(Chlamydomonas
reinhardtii) 		PF00566
(RabGAP-TBC) 		3 ARG A 259
HIS A 305
ARG A  61
 None
 1.08A 6dwdD-4p17A:
undetectable		 6dwdD-4p17A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p5b THYMIDYLATE SYNTHASE
THYX

(Streptomyces
cacaoi) 		PF02511
(Thy1) 		3 ARG A  86
HIS A  83
ARG A  82
 FAD  A 301 ( 2.9A)
None
None
 1.13A 6dwdD-4p5bA:
undetectable		 6dwdD-4p5bA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p8r GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE,
CYTOSOLIC

(Trypanosoma
brucei) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 ARG A  19
HIS A  51
ARG A  12
 None
 1.18A 6dwdD-4p8rA:
undetectable		 6dwdD-4p8rA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p9u FATTY ACID
METABOLISM REGULATOR
PROTEIN

(Vibrio cholerae) 		no annotation 3 ARG E 191
HIS E 195
ARG E 126
 None
 1.09A 6dwdD-4p9uE:
undetectable		 6dwdD-4p9uE:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pht GENERAL SECRETORY
PATHWAY PROTEIN E

(Vibrio
vulnificus) 		PF00437
(T2SSE) 		3 ARG A 150
HIS A 139
ARG A 217
 None
 1.13A 6dwdD-4phtA:
undetectable		 6dwdD-4phtA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqk LECTIN 2

(Agrocybe
aegerita) 		PF13517
(VCBS) 		3 ARG A 113
HIS A 117
ARG A 119
 None
NAG  A 501 (-3.7A)
None
 1.19A 6dwdD-4tqkA:
undetectable		 6dwdD-4tqkA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqk LECTIN 2

(Agrocybe
aegerita) 		PF13517
(VCBS) 		3 ARG A 169
HIS A 173
ARG A 175
 None
NAG  A 503 (-3.9A)
None
 1.09A 6dwdD-4tqkA:
undetectable		 6dwdD-4tqkA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ux8 GDNF FAMILY RECEPTOR
ALPHA-1

(Rattus
norvegicus) 		PF02351
(GDNF) 		3 ARG C 190
HIS C 193
ARG C 197
 None
 1.03A 6dwdD-4ux8C:
undetectable		 6dwdD-4ux8C:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgi GLUTAMATE
DEHYDROGENASE

(Burkholderia
thailandensis) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		3 ARG A 391
HIS A 387
ARG A 394
 None
 1.11A 6dwdD-4xgiA:
undetectable		 6dwdD-4xgiA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yj1 UNCHARACTERIZED
PROTEIN

(Trypanosoma
brucei) 		PF09818
(ABC_ATPase) 		3 ARG A 137
HIS A 140
ARG A 144
 None
 1.09A 6dwdD-4yj1A:
undetectable		 6dwdD-4yj1A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z64 PHYTOSULFOKINE
RECEPTOR 1
SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 1

(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		3 ARG A 635
HIS A 634
ARG C 144
 None
None
SO4  A 713 ( 4.4A)
 0.94A 6dwdD-4z64A:
undetectable		 6dwdD-4z64A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z6g MICROTUBULE-ACTIN
CROSS-LINKING FACTOR
1, ISOFORMS 1/2/3/5

(Homo sapiens) 		PF00307
(CH) 		3 ARG A 202
HIS A 201
ARG A 356
 None
 0.80A 6dwdD-4z6gA:
undetectable		 6dwdD-4z6gA:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4zwe DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1

(Homo sapiens) 		PF01966
(HD) 		3 ARG A 305
HIS A 517
ARG A 531
 None
 0.67A 6dwdD-4zweA:
57.7		 6dwdD-4zweA:
99.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csc CITRATE SYNTHASE

(Gallus gallus) 		PF00285
(Citrate_synt) 		3 ARG B 401
HIS B 235
ARG B 329
 None
 1.17A 6dwdD-5cscB:
undetectable		 6dwdD-5cscB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fmr INTRAFLAGELLAR
TRANSPORT PROTEIN
COMPONENT IFT52

(Chlamydomonas
reinhardtii) 		PF09822
(ABC_transp_aux) 		3 ARG A  36
HIS A  27
ARG A  39
 None
 1.15A 6dwdD-5fmrA:
undetectable		 6dwdD-5fmrA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fmr INTRAFLAGELLAR
TRANSPORT PROTEIN
COMPONENT IFT52

(Chlamydomonas
reinhardtii) 		PF09822
(ABC_transp_aux) 		3 ARG A 124
HIS A 127
ARG A 164
 SO4  A 903 (-4.0A)
SO4  A 903 (-3.7A)
SO4  A 903 (-3.2A)
 0.83A 6dwdD-5fmrA:
undetectable		 6dwdD-5fmrA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzr SNF2-FAMILY ATP
DEPENDENT CHROMATIN
REMODELING FACTOR
LIKE PROTEIN

(Thermothelomyces
thermophila) 		PF00176
(SNF2_N)
PF00271
(Helicase_C)
PF14619
(SnAC) 		3 ARG A 768
HIS A 771
ARG A 775
 KH2  A1203 (-4.6A)
None
KH2  A1203 (-3.5A)
 1.04A 6dwdD-5hzrA:
undetectable		 6dwdD-5hzrA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i2t PERIODIC TRYPTOPHAN
PROTEIN 2

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		3 ARG A  78
HIS A  54
ARG A 619
 None
 1.05A 6dwdD-5i2tA:
undetectable		 6dwdD-5i2tA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lux HOMEOBOX PROTEIN
CDX-1

(Homo sapiens) 		PF00046
(Homeobox) 		3 ARG K 177
HIS K 174
ARG K 205
 None
 1.00A 6dwdD-5luxK:
undetectable		 6dwdD-5luxK:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mb4 GLCNAC SPECIFIC
LECTIN

(Psathyrella) 		PF13517
(VCBS) 		3 ARG A  55
HIS A  59
ARG A  61
 None
NAG  A 510 ( 3.6A)
None
 1.13A 6dwdD-5mb4A:
undetectable		 6dwdD-5mb4A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mb4 GLCNAC SPECIFIC
LECTIN

(Psathyrella) 		PF13517
(VCBS) 		3 ARG A 112
HIS A 116
ARG A 118
 None
NDG  A 515 ( 3.9A)
NA  A 502 (-3.3A)
 1.09A 6dwdD-5mb4A:
undetectable		 6dwdD-5mb4A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mb4 GLCNAC SPECIFIC
LECTIN

(Psathyrella) 		PF13517
(VCBS) 		3 ARG A 167
HIS A 171
ARG A 173
 None
NDG  A 509 ( 3.9A)
None
 1.15A 6dwdD-5mb4A:
undetectable		 6dwdD-5mb4A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mb4 GLCNAC SPECIFIC
LECTIN

(Psathyrella) 		PF13517
(VCBS) 		3 ARG A 278
HIS A 282
ARG A 284
 None
NAG  A 511 (-4.1A)
None
 1.08A 6dwdD-5mb4A:
undetectable		 6dwdD-5mb4A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mb4 GLCNAC SPECIFIC
LECTIN

(Psathyrella) 		PF13517
(VCBS) 		3 ARG A 333
HIS A 337
ARG A 339
 None
NAG  A 513 ( 3.9A)
None
 1.16A 6dwdD-5mb4A:
undetectable		 6dwdD-5mb4A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mr4 GDNF FAMILY RECEPTOR
ALPHA-2

(Homo sapiens) 		no annotation 3 ARG C 198
HIS C 201
ARG C 205
 None
 1.14A 6dwdD-5mr4C:
undetectable		 6dwdD-5mr4C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5muf SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PGAM5, MITOCHONDRIAL

(Homo sapiens) 		PF00300
(His_Phos_1) 		3 ARG A 273
HIS A  99
ARG A 265
 None
 0.86A 6dwdD-5mufA:
undetectable		 6dwdD-5mufA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tge PHAGE TERMINASE
LARGE SUBUNIT

(Thermus virus
P74-26) 		PF17289
(Terminase_6C) 		3 ARG A 425
HIS A 427
ARG A 319
 None
 1.19A 6dwdD-5tgeA:
undetectable		 6dwdD-5tgeA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ur0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Naegleria
gruberi) 		no annotation 3 ARG A  18
HIS A  51
ARG A  11
 None
 1.16A 6dwdD-5ur0A:
undetectable		 6dwdD-5ur0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vm9 PROTEIN ARGONAUTE-3

(Homo sapiens) 		no annotation 3 ARG A 711
HIS A 712
ARG A 715
 A  B   9 ( 4.4A)
None
A  B   7 ( 3.4A)
 1.18A 6dwdD-5vm9A:
undetectable		 6dwdD-5vm9A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wax -

(-) 		no annotation 3 ARG A 147
HIS A  66
ARG A  71
 GOL  A 502 ( 4.3A)
None
None
 1.15A 6dwdD-5waxA:
undetectable		 6dwdD-5waxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wg6 HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2,POLYCOMB
PROTEIN SUZ12
(E.C.2.1.1.43)
CHIMERA

(Homo sapiens) 		no annotation 3 ARG A 594
HIS A 593
ARG A 608
 None
 1.19A 6dwdD-5wg6A:
undetectable		 6dwdD-5wg6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wo1 PERIPLASMIC
CHAPERONE SPY

(Escherichia
coli) 		PF07813
(LTXXQ) 		3 ARG A  61
HIS A  65
ARG A  62
 ARG  A  61 ( 0.6A)
HIS  A  65 ( 1.0A)
ARG  A  62 ( 0.6A)
 1.15A 6dwdD-5wo1A:
undetectable		 6dwdD-5wo1A:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xdm SEPTUM
SITE-DETERMINING
PROTEIN MINC

(Escherichia
coli) 		no annotation 3 ARG A  28
HIS A  45
ARG A  65
 None
 0.98A 6dwdD-5xdmA:
undetectable		 6dwdD-5xdmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yvi RNA-BINDING PROTEIN
FUS

(Homo sapiens) 		no annotation 3 ARG B 518
HIS B 517
ARG B 521
 None
 0.92A 6dwdD-5yviB:
undetectable		 6dwdD-5yviB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b5f NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE

(Yersinia
enterocolitica) 		no annotation 3 ARG A 275
HIS A 301
ARG A 281
 None
 1.15A 6dwdD-6b5fA:
undetectable		 6dwdD-6b5fA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6brs PUTATIVE ZINC
PROTEASE

(Pectobacterium
atrosepticum) 		no annotation 3 ARG A  88
HIS A  84
ARG A 108
 None
 1.02A 6dwdD-6brsA:
undetectable		 6dwdD-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN

(Archaeoglobus
fulgidus) 		no annotation 3 ARG A 126
HIS A 122
ARG A 117
 None
 1.17A 6dwdD-6fswA:
undetectable		 6dwdD-6fswA:
undetectable