SIMILAR PATTERNS OF AMINO ACIDS FOR 6DWD_C_GLYC713_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aq0 | 1,3-1,4-BETA-GLUCANASE (Hordeum vulgare) |
PF00332(Glyco_hydro_17) | 3 | GLN A 299TYR A 295ASN A 297 | None | 1.03A | 6dwdC-1aq0A:0.0 | 6dwdC-1aq0A:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1br2 | MYOSIN (Gallus gallus) |
PF00063(Myosin_head)PF02736(Myosin_N) | 3 | GLN A 361TYR A 313ASN A 364 | None | 0.86A | 6dwdC-1br2A:0.0 | 6dwdC-1br2A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1c | METHYLMALONYL-COAMUTASE ALPHA CHAIN (Propionibacteriumfreudenreichii) |
PF01642(MM_CoA_mutase)PF02310(B12-binding) | 3 | GLN A 110TYR A 102ASN A 105 | None | 0.91A | 6dwdC-1e1cA:0.0 | 6dwdC-1e1cA:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h7w | DIHYDROPYRIMIDINEDEHYDROGENASE (Sus scrofa) |
PF01180(DHO_dh)PF07992(Pyr_redox_2)PF14691(Fer4_20)PF14697(Fer4_21) | 3 | GLN A 852TYR A 110ASN A 108 | None | 1.08A | 6dwdC-1h7wA:0.0 | 6dwdC-1h7wA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i84 | SMOOTH MUSCLE MYOSINHEAVY CHAIN (Gallus gallus) |
PF00063(Myosin_head)PF00612(IQ)PF01576(Myosin_tail_1)PF02736(Myosin_N) | 3 | GLN S 361TYR S 313ASN S 364 | None | 0.89A | 6dwdC-1i84S:0.0 | 6dwdC-1i84S:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jkm | BREFELDIN A ESTERASE (Bacillussubtilis) |
PF07859(Abhydrolase_3) | 3 | GLN A 72TYR A 75ASN A 136 | None | 0.97A | 6dwdC-1jkmA:0.0 | 6dwdC-1jkmA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jxk | ALPHA-AMYLASE,SALIVARY (Homo sapiens) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C) | 3 | GLN A 232TYR A 247ASN A 250 | None | 1.07A | 6dwdC-1jxkA:0.0 | 6dwdC-1jxkA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mi1 | NEUROBEACHIN (Homo sapiens) |
PF02138(Beach)PF14844(PH_BEACH) | 3 | GLN A2149TYR A2210ASN A2230 | None | 1.01A | 6dwdC-1mi1A:0.0 | 6dwdC-1mi1A:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ose | PORCINEALPHA-AMYLASE (Sus scrofa) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C) | 3 | GLN A 232TYR A 247ASN A 250 | None | 1.01A | 6dwdC-1oseA:undetectable | 6dwdC-1oseA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sbp | SULFATE-BINDINGPROTEIN (Salmonellaenterica) |
PF13531(SBP_bac_11) | 3 | GLN A 40TYR A 17ASN A 21 | None | 0.99A | 6dwdC-1sbpA:undetectable | 6dwdC-1sbpA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1thm | THERMITASE (Thermoactinomycesvulgaris) |
PF00082(Peptidase_S8) | 3 | GLN A 19TYR A 274ASN A 272 | None | 0.98A | 6dwdC-1thmA:undetectable | 6dwdC-1thmA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1un1 | XYLOGLUCANENDOTRANSGLYCOSYLASE (Populus tremula) |
PF00722(Glyco_hydro_16)PF06955(XET_C) | 3 | GLN A 115TYR A 252ASN A 251 | None | 1.02A | 6dwdC-1un1A:undetectable | 6dwdC-1un1A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xkg | MAJOR MITE FECALALLERGEN DER P 1 (Dermatophagoidespteronyssinus) |
PF00112(Peptidase_C1) | 3 | GLN A 164TYR A 196ASN A 195 | None | 0.56A | 6dwdC-1xkgA:undetectable | 6dwdC-1xkgA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yjd | T-CELL-SPECIFICSURFACE GLYCOPROTEINCD28 (Homo sapiens) |
PF15910(V-set_2) | 3 | GLN C 88TYR C 85ASN C 87 | NoneNAG C 203 (-3.4A)NAG C 203 (-1.9A) | 0.86A | 6dwdC-1yjdC:undetectable | 6dwdC-1yjdC:12.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bb0 | IMIDAZOLONEPROPIONASE (Bacillussubtilis) |
PF01979(Amidohydro_1) | 3 | GLN A 14TYR A 390ASN A 389 | None | 1.06A | 6dwdC-2bb0A:undetectable | 6dwdC-2bb0A:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3d | 2-OXOPROPYL-COMREDUCTASE (Xanthobacterautotrophicus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 3 | GLN A 342TYR A 340ASN A 374 | None | 1.02A | 6dwdC-2c3dA:undetectable | 6dwdC-2c3dA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cnm | MODIFICATION OF 30SRIBOSOMAL SUBUNITPROTEIN S18 (Salmonellaenterica) |
PF00583(Acetyltransf_1) | 3 | GLN A 36TYR A 40ASN A 42 | None | 1.01A | 6dwdC-2cnmA:undetectable | 6dwdC-2cnmA:12.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eaa | 7S GLOBULIN-3 (Vigna angularis) |
PF00190(Cupin_1) | 3 | GLN A 37TYR A 38ASN A 36 | None | 0.94A | 6dwdC-2eaaA:undetectable | 6dwdC-2eaaA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fgq | OUTER MEMBRANE PORINPROTEIN 32 (Delftiaacidovorans) |
PF13609(Porin_4) | 3 | GLN X 325TYR X 289ASN X 291 | None | 0.97A | 6dwdC-2fgqX:undetectable | 6dwdC-2fgqX:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ho1 | TYPE 4 FIMBRIALBIOGENESIS PROTEINPILF (Pseudomonasaeruginosa) |
PF13414(TPR_11)PF13424(TPR_12) | 3 | GLN A 55TYR A 47ASN A 52 | None | 0.97A | 6dwdC-2ho1A:undetectable | 6dwdC-2ho1A:23.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iqf | CATALASE (Helicobacterpylori) |
PF00199(Catalase)PF06628(Catalase-rel) | 3 | GLN A 353TYR A 376ASN A 374 | MHO A 372 ( 4.7A)NoneNone | 1.05A | 6dwdC-2iqfA:undetectable | 6dwdC-2iqfA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jc4 | EXODEOXYRIBONUCLEASEIII (Neisseriameningitidis) |
PF03372(Exo_endo_phos) | 3 | GLN A 59TYR A 62ASN A 63 | None2HP A1261 ( 4.0A)None | 0.56A | 6dwdC-2jc4A:undetectable | 6dwdC-2jc4A:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o6q | VARIABLE LYMPHOCYTERECEPTOR A (Eptatretusburgeri) |
PF13855(LRR_8) | 3 | GLN A 67TYR A 89ASN A 91 | None | 1.00A | 6dwdC-2o6qA:undetectable | 6dwdC-2o6qA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uxy | ALIPHATIC AMIDASE (Pseudomonasaeruginosa) |
PF00795(CN_hydrolase) | 3 | GLN A 190TYR A 192ASN A 219 | C3Y A 166 ( 4.8A)C3Y A 166 ( 3.3A)None | 1.00A | 6dwdC-2uxyA:undetectable | 6dwdC-2uxyA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsa | MOSQUITOCIDAL TOXIN (Lysinibacillussphaericus) |
PF05588(Botulinum_HA-17)PF14200(RicinB_lectin_2) | 3 | GLN A 857TYR A 852ASN A 854 | None | 0.72A | 6dwdC-2vsaA:undetectable | 6dwdC-2vsaA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xh1 | KYNURENINE/ALPHA-AMINOADIPATEAMINOTRANSFERASE,MITOCHONDRIAL (Homo sapiens) |
PF00155(Aminotran_1_2) | 3 | GLN A 237TYR A 234ASN A 199 | None | 0.68A | 6dwdC-2xh1A:undetectable | 6dwdC-2xh1A:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y24 | XYLANASE (Dickeyachrysanthemi) |
PF02055(Glyco_hydro_30)PF17189(Glyco_hydro_30C) | 3 | GLN A 42TYR A 41ASN A 282 | None | 0.98A | 6dwdC-2y24A:undetectable | 6dwdC-2y24A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ybx | PHOSPHATIDYLINOSITOL-5-PHOSPHATE4-KINASE TYPE-2ALPHA (Homo sapiens) |
PF01504(PIP5K) | 3 | GLN A 32TYR A 30ASN A 83 | None | 0.98A | 6dwdC-2ybxA:undetectable | 6dwdC-2ybxA:25.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yn7 | OUTER SURFACEPROTEIN (Borreliellaburgdorferi) |
PF05714(Borrelia_lipo_1) | 3 | GLN A 364TYR A 392ASN A 395 | None | 0.90A | 6dwdC-2yn7A:undetectable | 6dwdC-2yn7A:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z4t | BETA-GALACTOSIDEALPHA-2,6-SIALYLTRANSFERASE (Photobacteriumsp. JT-ISH-224) |
PF11477(PM0188) | 3 | GLN A 346TYR A 349ASN A 350 | None | 0.99A | 6dwdC-2z4tA:undetectable | 6dwdC-2z4tA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9s | D-ARABINOSEISOMERASE (Aeribacilluspallidus) |
PF02952(Fucose_iso_C)PF07881(Fucose_iso_N1)PF07882(Fucose_iso_N2) | 3 | GLN A 56TYR A 52ASN A 54 | None | 1.04A | 6dwdC-3a9sA:undetectable | 6dwdC-3a9sA:22.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bkh | LYTICTRANSGLYCOSYLASE (Pseudomonasvirus phiKZ) |
PF01464(SLT)PF01471(PG_binding_1) | 3 | GLN A 245TYR A 248ASN A 249 | None | 1.04A | 6dwdC-3bkhA:undetectable | 6dwdC-3bkhA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bwq | CAPSID PROTEIN VP1 (Macaca mulattapolyomavirus 1) |
PF00718(Polyoma_coat) | 3 | GLN A 187TYR A 168ASN A 167 | None | 0.99A | 6dwdC-3bwqA:undetectable | 6dwdC-3bwqA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bz5 | INTERNALIN-J (Listeriamonocytogenes) |
PF12799(LRR_4) | 3 | GLN A 356TYR A 375ASN A 377 | None | 0.93A | 6dwdC-3bz5A:undetectable | 6dwdC-3bz5A:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c5i | CHOLINE KINASE (Plasmodiumknowlesi) |
PF01633(Choline_kinase) | 3 | GLN A 220TYR A 259ASN A 222 | CHT A1001 (-3.2A)CHT A1001 ( 4.6A) MG A 370 ( 4.4A) | 0.99A | 6dwdC-3c5iA:undetectable | 6dwdC-3c5iA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3clw | CONSERVED EXPORTEDPROTEIN (Bacteroidesfragilis) |
PF14587(Glyco_hydr_30_2) | 3 | GLN A 40TYR A 39ASN A 373 | None | 1.05A | 6dwdC-3clwA:undetectable | 6dwdC-3clwA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cym | UNCHARACTERIZEDPROTEIN BAD_0989 (Bifidobacteriumadolescentis) |
PF00570(HRDC)PF01612(DNA_pol_A_exo1) | 3 | GLN A 412TYR A 390ASN A 393 | None | 1.04A | 6dwdC-3cymA:undetectable | 6dwdC-3cymA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d6s | ALLERGEN DER F I (Dermatophagoidesfarinae) |
PF00112(Peptidase_C1) | 3 | GLN A 85TYR A 117ASN A 116 | None | 0.70A | 6dwdC-3d6sA:undetectable | 6dwdC-3d6sA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dwl | ACTIN-RELATEDPROTEIN 3ACTIN-RELATEDPROTEIN 2/3 COMPLEXSUBUNIT 2 (Schizosaccharomycespombe;Schizosaccharomycespombe) |
PF00022(Actin)PF04045(P34-Arc) | 3 | GLN D 29TYR A 21ASN A 24 | None | 1.01A | 6dwdC-3dwlD:undetectable | 6dwdC-3dwlD:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e53 | FATTY-ACID-COALIGASE FADD28 (Mycobacteriumtuberculosis) |
PF00501(AMP-binding) | 3 | GLN A 194TYR A 337ASN A 191 | None | 0.91A | 6dwdC-3e53A:undetectable | 6dwdC-3e53A:25.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqa | GLUCOAMYLASE (Aspergillusniger) |
PF00723(Glyco_hydro_15) | 3 | GLN A 425TYR A 336ASN A 339 | None | 1.07A | 6dwdC-3eqaA:undetectable | 6dwdC-3eqaA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7n | NUCLEOPORIN NUP120 (Saccharomycescerevisiae) |
PF11715(Nup160) | 3 | GLN A 104TYR A 106ASN A 103 | None | 1.02A | 6dwdC-3h7nA:undetectable | 6dwdC-3h7nA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hbu | SECRETED PROTEASE C (Dickeyachrysanthemi) |
PF00353(HemolysinCabind)PF00413(Peptidase_M10)PF08548(Peptidase_M10_C) | 3 | GLN P 313TYR P 309ASN P 311 | None | 1.07A | 6dwdC-3hbuP:undetectable | 6dwdC-3hbuP:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3io0 | ETUB PROTEIN (Clostridiumkluyveri) |
PF00936(BMC) | 3 | GLN A 199TYR A 184ASN A 187 | None | 0.95A | 6dwdC-3io0A:undetectable | 6dwdC-3io0A:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4p | CAPSID PROTEIN VP1 (Adeno-associatedvirus) |
PF00740(Parvo_coat) | 3 | GLN A 299TYR A 702ASN A 303 | None | 1.05A | 6dwdC-3j4pA:undetectable | 6dwdC-3j4pA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jr1 | PUTATIVEFRUCTOSAMINE-3-KINASE (Histophilussomni) |
PF03881(Fructosamin_kin) | 3 | GLN A 156TYR A 267ASN A 264 | None | 0.81A | 6dwdC-3jr1A:undetectable | 6dwdC-3jr1A:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm8 | THIAMINEPYROPHOSPHOKINASE (Bacillussubtilis) |
PF04263(TPK_catalytic)PF04265(TPK_B1_binding) | 3 | GLN A 98TYR A 21ASN A 5 | None | 1.05A | 6dwdC-3lm8A:undetectable | 6dwdC-3lm8A:15.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ng9 | CAPSID PROTEIN (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 3 | GLN A 298TYR A 701ASN A 302 | None | 1.00A | 6dwdC-3ng9A:undetectable | 6dwdC-3ng9A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nwn | KINESIN-LIKE PROTEINKIF9 (Homo sapiens) |
PF00225(Kinesin) | 3 | GLN A 80TYR A 85ASN A 310 | None | 0.97A | 6dwdC-3nwnA:undetectable | 6dwdC-3nwnA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t5v | NUCLEAR MRNA EXPORTPROTEIN THP1 (Saccharomycescerevisiae) |
PF01399(PCI) | 3 | GLN B 235TYR B 230ASN B 233 | None | 0.89A | 6dwdC-3t5vB:undetectable | 6dwdC-3t5vB:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ux1 | CAPSID PROTEIN VP1 (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 3 | GLN A 299TYR A 701ASN A 303 | None | 1.06A | 6dwdC-3ux1A:undetectable | 6dwdC-3ux1A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v8h | THYMIDYLATE SYNTHASE (Burkholderiathailandensis) |
PF00303(Thymidylat_synt) | 3 | GLN A 260TYR A 257ASN A 259 | NoneCIT A 400 (-4.5A)None | 1.01A | 6dwdC-3v8hA:undetectable | 6dwdC-3v8hA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wq4 | BETA-PRIMEVEROSIDASE (Camelliasinensis) |
PF00232(Glyco_hydro_1) | 3 | GLN A 371TYR A 275ASN A 348 | None | 0.87A | 6dwdC-3wq4A:undetectable | 6dwdC-3wq4A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cvu | BETA-MANNOSIDASE (Trichodermaharzianum) |
PF00703(Glyco_hydro_2) | 3 | GLN A 85TYR A 44ASN A 42 | NoneNAG A1972 ( 4.8A)None | 0.93A | 6dwdC-4cvuA:undetectable | 6dwdC-4cvuA:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d10 | COP9 SIGNALOSOMECOMPLEX SUBUNIT 3 (Homo sapiens) |
PF01399(PCI) | 3 | GLN C 132TYR C 161ASN C 136 | None | 0.97A | 6dwdC-4d10C:undetectable | 6dwdC-4d10C:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ffb | PROTEIN STU2 (Saccharomycescerevisiae) |
no annotation | 3 | GLN C 202TYR C 164ASN C 161 | None | 0.94A | 6dwdC-4ffbC:undetectable | 6dwdC-4ffbC:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fuu | LEUCINEAMINOPEPTIDASE (Bacteroidesthetaiotaomicron) |
PF04389(Peptidase_M28) | 3 | GLN A 90TYR A 204ASN A 106 | None | 1.00A | 6dwdC-4fuuA:undetectable | 6dwdC-4fuuA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h32 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 3 | GLN A 188TYR A 192ASN A 194 | None | 0.69A | 6dwdC-4h32A:undetectable | 6dwdC-4h32A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcd | MAJOR CAPSID PROTEINVP1 (Humanpolyomavirus 2) |
PF00718(Polyoma_coat) | 3 | GLN A 179TYR A 160ASN A 159 | None | 0.91A | 6dwdC-4jcdA:undetectable | 6dwdC-4jcdA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k90 | EXTRACELLULARMETALLOPROTEINASEMEP (Aspergillusfumigatus) |
PF02128(Peptidase_M36) | 3 | GLN A 298TYR A 307ASN A 383 | None | 1.07A | 6dwdC-4k90A:undetectable | 6dwdC-4k90A:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kbx | UNCHARACTERIZEDPROTEIN YHFX (Escherichiacoli) |
PF01168(Ala_racemase_N) | 3 | GLN A 230TYR A 57ASN A 232 | None | 1.06A | 6dwdC-4kbxA:undetectable | 6dwdC-4kbxA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lf0 | ALIPHATIC AMIDASE (Bacillus sp.(in: Bacteria)) |
PF00795(CN_hydrolase) | 3 | GLN A 190TYR A 192ASN A 219 | None | 1.01A | 6dwdC-4lf0A:undetectable | 6dwdC-4lf0A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lql | L-ARABINOSEISOMERASE (Lactobacillusfermentum) |
PF02610(Arabinose_Isome)PF11762(Arabinose_Iso_C) | 3 | GLN A 125TYR A 19ASN A 122 | None | 0.88A | 6dwdC-4lqlA:undetectable | 6dwdC-4lqlA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mae | METHANOLDEHYDROGENASE (Methylacidiphilumfumariolicum) |
PF13360(PQQ_2) | 3 | GLN A 95TYR A 71ASN A 73 | None | 1.06A | 6dwdC-4maeA:undetectable | 6dwdC-4maeA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mj0 | VP1 CAPSID PROTEIN (Humanpolyomavirus 1) |
PF00718(Polyoma_coat) | 3 | GLN A 187TYR A 168ASN A 167 | None | 0.91A | 6dwdC-4mj0A:undetectable | 6dwdC-4mj0A:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mtk | VGRG1 (Pseudomonasaeruginosa) |
PF05954(Phage_GPD) | 3 | GLN A 466TYR A 458ASN A 463 | None | 0.99A | 6dwdC-4mtkA:undetectable | 6dwdC-4mtkA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4npr | XYLOGLUCAN-SPECIFICENDO-BETA-1,4-GLUCANASE GH12 (Aspergillusniveus) |
PF01670(Glyco_hydro_12) | 3 | GLN A 215TYR A 37ASN A 83 | None | 1.04A | 6dwdC-4nprA:undetectable | 6dwdC-4nprA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxq | D-GLUCURONYL C5EPIMERASE B (Danio rerio) |
PF06662(C5-epim_C) | 3 | GLN A 555TYR A 131ASN A 552 | None | 0.88A | 6dwdC-4pxqA:undetectable | 6dwdC-4pxqA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qbj | GLYCYLPEPTIDEN-TETRADECANOYLTRANSFERASE (Aspergillusfumigatus) |
PF01233(NMT)PF02799(NMT_C) | 3 | GLN A 245TYR A 244ASN A 463 | None | 0.82A | 6dwdC-4qbjA:undetectable | 6dwdC-4qbjA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rgg | PUTATIVE PHAGESTRUCTURAL PROTEIN (Lactococcusphage 1358) |
no annotation | 3 | GLN A 27TYR A 182ASN A 179 | None | 0.91A | 6dwdC-4rggA:undetectable | 6dwdC-4rggA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rso | CAPSID PROTEIN VP1 (Non-humanprimateAdeno-associatedvirus) |
PF00740(Parvo_coat) | 3 | GLN A 299TYR A 701ASN A 303 | None | 0.95A | 6dwdC-4rsoA:undetectable | 6dwdC-4rsoA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4trq | NUCLEAR MRNA EXPORTPROTEIN THP1 (Saccharomycescerevisiae) |
PF01399(PCI) | 3 | GLN B 235TYR B 230ASN B 233 | None | 0.93A | 6dwdC-4trqB:undetectable | 6dwdC-4trqB:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tu3 | PHOSPHOINOSITIDEPHOSPHATASE SAC1 (Saccharomycescerevisiae) |
PF02383(Syja_N) | 3 | GLN X 292TYR X 296ASN X 299 | None | 1.04A | 6dwdC-4tu3X:undetectable | 6dwdC-4tu3X:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u60 | STRUCTURAL PROTEINVP1 (Humanpolyomavirus 8) |
PF00718(Polyoma_coat) | 3 | GLN A 193TYR A 172ASN A 171 | None | 0.96A | 6dwdC-4u60A:undetectable | 6dwdC-4u60A:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xmm | NUCLEOPORIN NUP120 (Saccharomycescerevisiae) |
no annotation | 3 | GLN E 104TYR E 106ASN E 103 | None | 0.91A | 6dwdC-4xmmE:undetectable | 6dwdC-4xmmE:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zkt | BONTOXILYSIN A (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07951(Toxin_R_bind_C)PF07952(Toxin_trans)PF07953(Toxin_R_bind_N) | 3 | GLN A1130TYR A1149ASN A1151 | None | 1.02A | 6dwdC-4zktA:undetectable | 6dwdC-4zktA:17.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ao0 | DEOXYNUCLEOSIDETRIPHOSPHATETRIPHOSPHOHYDROLASESAMHD1 (Homo sapiens) |
PF01966(HD) | 3 | GLN A 447TYR A 450ASN A 452 | None | 0.37A | 6dwdC-5ao0A:49.5 | 6dwdC-5ao0A:85.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c3l | NUCLEOPORIN NUP58NANOBODY NB15 (Xenopus laevis;Camelusdromedarius) |
PF15967(Nucleoporin_FG2)PF07686(V-set) | 3 | GLN B 363TYR D 100ASN D 98 | None | 1.05A | 6dwdC-5c3lB:undetectable | 6dwdC-5c3lB:15.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cer | BD0816BD3460 (Bdellovibriobacteriovorus;Bdellovibriobacteriovorus) |
PF02113(Peptidase_S13)PF12796(Ank_2) | 3 | GLN A 396TYR B 174ASN A 399 | None | 1.02A | 6dwdC-5cerA:undetectable | 6dwdC-5cerA:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ev7 | CONSERVED DOMAINPROTEIN (Bacillusanthracis) |
PF13402(Peptidase_M60)PF17291(M60-like_N) | 3 | GLN A 367TYR A 448ASN A 364 | None | 1.03A | 6dwdC-5ev7A:undetectable | 6dwdC-5ev7A:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fly | FERRICHROME-BINDINGPERIPLASMIC PROTEIN (Staphylococcuspseudintermedius) |
PF01497(Peripla_BP_2) | 3 | GLN A 184TYR A 113ASN A 174 | None | 0.96A | 6dwdC-5flyA:undetectable | 6dwdC-5flyA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fp1 | TONB-DEPENDENTSIDEROPHORE RECEPTOR (Acinetobacterbaumannii) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | GLN A 607TYR A 610ASN A 595 | None | 1.02A | 6dwdC-5fp1A:undetectable | 6dwdC-5fp1A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq6 | SUSC/RAGA FAMILYTONB-LINKED OUTERMEMBRANE PROTEIN (Bacteroidesthetaiotaomicron) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | GLN B 276TYR B 255ASN B 257 | None | 0.96A | 6dwdC-5fq6B:undetectable | 6dwdC-5fq6B:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fv0 | ESSC (Geobacillusthermodenitrificans) |
PF01580(FtsK_SpoIIIE) | 3 | GLN A1026TYR A1022ASN A1023 | None | 1.02A | 6dwdC-5fv0A:undetectable | 6dwdC-5fv0A:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gs2 | REPEBODYANTI-REPEBODY (Escherichiacoli;Mus musculus) |
PF11921(DUF3439)PF12354(Internalin_N)PF13855(LRR_8)PF07686(V-set) | 3 | GLN B 192TYR D 54ASN D 52 | None | 0.78A | 6dwdC-5gs2B:undetectable | 6dwdC-5gs2B:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 3 | GLN B 514TYR B 506ASN B 511 | None | 0.78A | 6dwdC-5gztB:undetectable | 6dwdC-5gztB:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5izt | OUTER SURFACEPROTEIN (Borreliellaburgdorferi) |
PF05714(Borrelia_lipo_1) | 3 | GLN A 364TYR A 392ASN A 395 | None | 0.89A | 6dwdC-5iztA:undetectable | 6dwdC-5iztA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lfn | CHONDROADHERIN (Homo sapiens) |
PF00560(LRR_1)PF01462(LRRNT)PF13855(LRR_8) | 3 | GLN A 153TYR A 177ASN A 155 | None | 0.80A | 6dwdC-5lfnA:undetectable | 6dwdC-5lfnA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m3h | POLYMERASE ACIDICPROTEIN (Influenza Avirus) |
PF00603(Flu_PA) | 3 | GLN A 212TYR A 226ASN A 216 | None | 1.07A | 6dwdC-5m3hA:undetectable | 6dwdC-5m3hA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mc9 | LAMININ SUBUNITBETA-1LAMININ SUBUNITGAMMA-1 (Mus musculus;Mus musculus) |
no annotationno annotation | 3 | GLN C1566TYR B1747ASN B1750 | None | 1.06A | 6dwdC-5mc9C:undetectable | 6dwdC-5mc9C:9.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nb8 | PROTEIN NOV HOMOLOG (Rattusnorvegicus) |
PF00093(VWC) | 3 | GLN A 122TYR A 123ASN A 120 | None | 0.99A | 6dwdC-5nb8A:undetectable | 6dwdC-5nb8A:9.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o0s | GLUCOSYLCERAMIDASE (Thermoanaerobacteriumxylanolyticum) |
PF04685(DUF608)PF12215(Glyco_hydr_116N)PF17168(DUF5127) | 3 | GLN A 616TYR A 635ASN A 632 | None | 0.67A | 6dwdC-5o0sA:undetectable | 6dwdC-5o0sA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tgf | UNCHARACTERIZEDPROTEIN (Bacteroidesdorei) |
PF00144(Beta-lactamase) | 3 | GLN A 283TYR A 282ASN A 297 | None | 1.00A | 6dwdC-5tgfA:undetectable | 6dwdC-5tgfA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vh2 | CADHERIN-23 (Mus musculus) |
no annotation | 3 | GLN A1189TYR A1277ASN A1191 | None | 1.06A | 6dwdC-5vh2A:undetectable | 6dwdC-5vh2A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w4b | ADENOSYLHOMOCYSTEINASE (Homo sapiens) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 3 | GLN A 251TYR A 221ASN A 248 | NoneNoneNAD A 501 (-3.2A) | 1.05A | 6dwdC-5w4bA:undetectable | 6dwdC-5w4bA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wzr | ALPHA-N-ACETYLGALACTOSAMINIDASE (Bifidobacteriumbifidum) |
PF11308(Glyco_hydro_129) | 3 | GLN A 136TYR A 515ASN A 516 | None | 1.04A | 6dwdC-5wzrA:undetectable | 6dwdC-5wzrA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ykh | PUMILIO HOMOLOG 1 (Homo sapiens) |
no annotation | 3 | GLN A 227TYR A 224ASN A 223 | None | 0.68A | 6dwdC-5ykhA:undetectable | 6dwdC-5ykhA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bpq | TRANSIENT RECEPTORPOTENTIAL CATIONCHANNEL SUBFAMILY MMEMBER 8 (Ficedulaalbicollis) |
no annotation | 3 | GLN A 173TYR A 170ASN A 199 | None | 0.92A | 6dwdC-6bpqA:undetectable | 6dwdC-6bpqA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ehs | HYDROGENASE-2 LARGECHAIN (Escherichiacoli) |
no annotation | 3 | GLN L 442TYR L 90ASN L 93 | None | 0.76A | 6dwdC-6ehsL:undetectable | 6dwdC-6ehsL:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eks | SIALIDASE (Vibrio cholerae) |
no annotation | 3 | GLN A 677TYR A 673ASN A 695 | None | 0.86A | 6dwdC-6eksA:undetectable | 6dwdC-6eksA:20.71 |