SIMILAR PATTERNS OF AMINO ACIDS FOR 6DK1_C_GM4C301_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE

(Enterobacter
cloacae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		5 VAL A 429
ALA A 420
TYR A 412
THR A 413
ALA A 417
 None
 1.28A 6dk1C-1ovmA:
0.0		 6dk1C-1ovmA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qni NITROUS-OXIDE
REDUCTASE

(Marinobacter
hydrocarbonoclasticus) 		no annotation 5 ALA A 379
TYR A 194
TYR A  90
ASP A 191
ALA A 387
 None
 1.23A 6dk1C-1qniA:
0.0		 6dk1C-1qniA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1suv TRANSFERRIN RECEPTOR
PROTEIN 1

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		5 VAL A 404
ALA A 451
TRP A 453
TYR A 470
LEU A 474
 None
 1.28A 6dk1C-1suvA:
0.0		 6dk1C-1suvA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ut9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		5 VAL A 392
ALA A 495
ASP A 607
GLU A 606
ALA A 541
 None
 1.22A 6dk1C-1ut9A:
undetectable		 6dk1C-1ut9A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uzg MAJOR ENVELOPE
PROTEIN E

(Dengue virus) 		PF00869
(Flavi_glycoprot)
PF02832
(Flavi_glycop_C) 		5 VAL A 130
LEU A 189
TYR A 137
THR A  48
ALA A  50
 None
 1.13A 6dk1C-1uzgA:
0.0		 6dk1C-1uzgA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vft ALANINE RACEMASE

(Streptomyces
lavendulae) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		5 VAL A 102
TRP A  92
TRP A 108
THR A 159
ALA A 124
 None
 1.50A 6dk1C-1vftA:
0.1		 6dk1C-1vftA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a2f EXOCYST COMPLEX
COMPONENT SEC15

(Drosophila
melanogaster) 		PF04091
(Sec15) 		5 VAL X 294
ALA X 243
TYR X 305
GLU X 301
ALA X 246
 None
 1.42A 6dk1C-2a2fX:
undetectable		 6dk1C-2a2fX:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a2f EXOCYST COMPLEX
COMPONENT SEC15

(Drosophila
melanogaster) 		PF04091
(Sec15) 		5 VAL X 294
TYR X 305
LEU X 302
GLU X 301
ALA X 246
 None
 1.23A 6dk1C-2a2fX:
undetectable		 6dk1C-2a2fX:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2glf PROBABLE M18-FAMILY
AMINOPEPTIDASE 1

(Thermotoga
maritima) 		PF02127
(Peptidase_M18) 		5 ALA A  93
LEU A 423
TYR A 445
THR A 258
ALA A 256
 None
 1.15A 6dk1C-2glfA:
undetectable		 6dk1C-2glfA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfc HYPOTHETICAL PROTEIN
RV0098/MT0107

(Mycobacterium
tuberculosis) 		PF10862
(FcoT) 		5 VAL A  53
ALA A  89
LEU A 145
TYR A 110
ALA A  93
 None
 1.35A 6dk1C-2pfcA:
0.0		 6dk1C-2pfcA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5e PUTATIVE SERINE
PROTEASE

(Mamastrovirus 1) 		PF13365
(Trypsin_2) 		5 ALA A 503
TYR A 521
LEU A 526
TYR A 473
ALA A 436
 None
 1.37A 6dk1C-2w5eA:
0.0		 6dk1C-2w5eA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afg SUBTILISIN-LIKE
SERINE PROTEASE

(Thermococcus
kodakarensis) 		PF00082
(Peptidase_S8)
PF04151
(PPC) 		5 VAL A 243
ALA A 369
TRP A 268
THR A 362
ALA A 366
 None
 1.18A 6dk1C-3afgA:
undetectable		 6dk1C-3afgA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bh2 ACETOACETATE
DECARBOXYLASE

(Clostridium
acetobutylicum) 		PF06314
(ADC) 		5 VAL A 106
TYR A  74
LEU A  98
GLU A  76
THR A  68
 None
 1.43A 6dk1C-3bh2A:
undetectable		 6dk1C-3bh2A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD

(Shewanella
denitrificans) 		PF14518
(Haem_oxygenas_2) 		5 VAL A 142
ALA A 139
TRP A 138
TYR A  43
TYR A  50
 None
 1.25A 6dk1C-3ddeA:
undetectable		 6dk1C-3ddeA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dde TENA/THI-4 PROTEIN,
DOMAIN OF UNKNOWN
FUNCTION WITH A HEME
OXYGENASE-LIKE FOLD

(Shewanella
denitrificans) 		PF14518
(Haem_oxygenas_2) 		5 VAL A 142
ALA A 139
TRP A 138
TYR A  50
THR A  47
 None
 1.43A 6dk1C-3ddeA:
undetectable		 6dk1C-3ddeA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dip ENOLASE

(unidentified) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 VAL A 239
ALA A 235
LEU A 218
THR A 262
ALA A 264
 None
 1.49A 6dk1C-3dipA:
undetectable		 6dk1C-3dipA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3drk OLIGOPEPTIDE-BINDING
PROTEIN OPPA

(Lactococcus
lactis) 		PF00496
(SBP_bac_5) 		5 ALA A 384
TYR A 307
LEU A 327
TYR A 376
ALA A 339
 None
 1.30A 6dk1C-3drkA:
undetectable		 6dk1C-3drkA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gt5 N-ACETYLGLUCOSAMINE
2-EPIMERASE

(Xylella
fastidiosa) 		PF07221
(GlcNAc_2-epim) 		5 ALA A 330
TRP A 339
LEU A  18
ASP A  11
ALA A 326
 None
 1.12A 6dk1C-3gt5A:
undetectable		 6dk1C-3gt5A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k6h NITROREDUCTASE
FAMILY PROTEIN

(Agrobacterium
fabrum) 		PF00881
(Nitroreductase) 		5 VAL A  99
ALA A  96
LEU A 146
GLU A 144
THR A  91
 None
None
None
FMN  A 199 ( 4.0A)
None
 1.32A 6dk1C-3k6hA:
undetectable		 6dk1C-3k6hA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kg9 CURK

(Lyngbya
majuscula) 		PF14765
(PS-DH) 		5 VAL A1211
ALA A1144
LEU A1238
ASP A1169
ALA A1178
 None
 1.44A 6dk1C-3kg9A:
undetectable		 6dk1C-3kg9A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lop SUBSTRATE BINDING
PERIPLASMIC PROTEIN

(Ralstonia
solanacearum) 		PF13458
(Peripla_BP_6) 		5 VAL A 133
TYR A 352
LEU A 349
TYR A  62
ALA A 322
 None
 1.25A 6dk1C-3lopA:
undetectable		 6dk1C-3lopA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nqx SECRETED
METALLOPROTEASE
MCP02

(Pseudoalteromonas
sp. SM9913) 		PF01447
(Peptidase_M4)
PF02868
(Peptidase_M4_C) 		5 ALA A 480
TYR A 434
LEU A 495
TRP A 447
ALA A 459
 None
 1.50A 6dk1C-3nqxA:
undetectable		 6dk1C-3nqxA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nt8 ANCYLOSTOMA SECRETED
PROTEIN 1

(Necator
americanus) 		PF00188
(CAP) 		5 ALA A 325
TRP A 329
TYR A 276
LEU A 370
ALA A 322
 None
 1.48A 6dk1C-3nt8A:
undetectable		 6dk1C-3nt8A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qw3 OROTIDINE-5-PHOSPHAT
E
DECARBOXYLASE/OROTAT
E
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE
(OMPDCASE-OPRTASE,
PUTATIVE)

(Leishmania
infantum) 		PF00215
(OMPdecase) 		5 VAL A  79
ALA A 105
ASP A  21
THR A 109
ALA A 107
 None
None
SO4  A 257 ( 4.4A)
None
None
 1.45A 6dk1C-3qw3A:
undetectable		 6dk1C-3qw3A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qw4 UMP SYNTHASE

(Leishmania
donovani) 		PF00156
(Pribosyltran)
PF00215
(OMPdecase) 		5 VAL B  79
ALA B 105
ASP B  21
THR B 109
ALA B 107
 None
None
U5P  B7485 (-3.4A)
None
None
 1.42A 6dk1C-3qw4B:
undetectable		 6dk1C-3qw4B:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sbq NITROUS-OXIDE
REDUCTASE

(Pseudomonas
stutzeri) 		no annotation 5 ALA A 436
TYR A 246
TYR A 140
ASP A 243
ALA A 444
 None
 1.34A 6dk1C-3sbqA:
undetectable		 6dk1C-3sbqA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d72 GLYCOSIDE HYDROLASE

(Streptococcus
pneumoniae) 		PF08306
(Glyco_hydro_98M)
PF08307
(Glyco_hydro_98C) 		5 ALA A 524
TYR A 440
ASP A 657
GLU A 710
THR A 520
 FUC  A2007 ( 4.0A)
FUC  A2007 (-4.4A)
None
FUC  A2007 ( 2.9A)
None
 1.22A 6dk1C-4d72A:
undetectable		 6dk1C-4d72A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4leh BILE ACID 7-ALPHA
DEHYDRATASE, BAIE

([Clostridium]
scindens) 		PF13577
(SnoaL_4) 		5 TYR A  33
LEU A  45
TYR A 129
ASP A  38
THR A 145
 None
 1.38A 6dk1C-4lehA:
undetectable		 6dk1C-4lehA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m8u OLIGO-1,6-GLUCOSIDAS
E 1

(Bacillus
subtilis) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		5 VAL A 357
ALA A 555
LEU A 304
ASP A 492
ALA A 353
 None
 1.39A 6dk1C-4m8uA:
undetectable		 6dk1C-4m8uA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE

(Danio rerio) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		5 ALA A 267
TRP A 213
TYR A 306
LEU A 293
ALA A 271
 None
 1.35A 6dk1C-4qpcA:
undetectable		 6dk1C-4qpcA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3u 2-HYDROXYISOBUTYRYL-
COA MUTASE LARGE
SUBUNIT

(Aquincola
tertiaricarbonis) 		PF01642
(MM_CoA_mutase) 		5 ALA A  56
TRP A   3
TYR A 409
THR A  51
ALA A  53
 None
 1.40A 6dk1C-4r3uA:
undetectable		 6dk1C-4r3uA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zoh PUTATIVE
OXIDOREDUCTASE
FAD-BINDING SUBUNIT
PUTATIVE
OXIDOREDUCTASE
IRON-SULFUR SUBUNIT

(Sulfurisphaera
tokodaii;
Sulfurisphaera
tokodaii) 		PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C)
PF00111
(Fer2)
PF01799
(Fer2_2) 		5 VAL C  69
TYR B   8
LEU B  30
GLU B  52
ALA C  71
 None
 1.33A 6dk1C-4zohC:
undetectable		 6dk1C-4zohC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah5 LEUCINE--TRNA LIGASE

(Agrobacterium
tumefaciens) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2) 		5 ALA A 592
LEU A 715
TYR A   3
TRP A  16
ALA A 594
 None
 1.39A 6dk1C-5ah5A:
undetectable		 6dk1C-5ah5A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b39 KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 3DL1

(Homo sapiens) 		PF00047
(ig) 		5 VAL G  92
ALA G  16
LEU G  39
THR G  25
ALA G  12
 None
 1.41A 6dk1C-5b39G:
undetectable		 6dk1C-5b39G:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7z UNCHARACTERIZED
PROTEIN TM_0416

(Thermotoga
maritima) 		PF01261
(AP_endonuc_2) 		5 VAL A   6
LEU A 180
GLU A 149
THR A  69
ALA A  41
 None
None
NI  A 305 (-2.4A)
None
None
 1.17A 6dk1C-5b7zA:
undetectable		 6dk1C-5b7zA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d3m ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA1

(Lactobacillus
delbrueckii) 		PF00005
(ABC_tran) 		5 VAL A 213
ALA A  37
LEU A 237
ASP A 217
ALA A 207
 None
 1.09A 6dk1C-5d3mA:
undetectable		 6dk1C-5d3mA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5edu MALTOSE-BINDING
PERIPLASMIC PROTEIN,
HISTONE DEACETYLASE
6 CHIMERA

(Escherichia
coli;
Homo sapiens) 		no annotation 5 ALA B 582
TYR B 570
GLU B 502
THR B 575
ALA B 579
 None
 1.19A 6dk1C-5eduB:
undetectable		 6dk1C-5eduB:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5evl BETA-LACTAMASE

(Chromobacterium
violaceum) 		PF00144
(Beta-lactamase) 		5 VAL A 337
ALA A  32
LEU A  63
THR A  59
ALA A  30
 None
 1.31A 6dk1C-5evlA:
undetectable		 6dk1C-5evlA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT DELTA

(Saccharomyces
cerevisiae) 		PF00118
(Cpn60_TCP1) 		5 VAL d 285
ALA d 232
LEU d 215
THR d 364
ALA d 347
 None
 1.45A 6dk1C-5gw5d:
undetectable		 6dk1C-5gw5d:
18.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hk2 SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1

(Homo sapiens) 		PF04622
(ERG2_Sigma1R) 		11 VAL A  84
ALA A  86
TRP A  89
TYR A 103
LEU A 105
TYR A 120
ASP A 126
TRP A 164
GLU A 172
THR A 181
ALA A 185
 61V  A 301 (-4.5A)
None
None
61V  A 301 ( 4.3A)
None
None
61V  A 301 (-3.2A)
None
61V  A 301 (-2.9A)
61V  A 301 ( 4.7A)
61V  A 301 ( 4.2A)
 0.70A 6dk1C-5hk2A:
33.7		 6dk1C-5hk2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hk2 SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1

(Homo sapiens) 		PF04622
(ERG2_Sigma1R) 		5 VAL A  84
LEU A 105
ASP A 126
GLU A 172
ALA A  86
 61V  A 301 (-4.5A)
None
61V  A 301 (-3.2A)
61V  A 301 (-2.9A)
None
 1.44A 6dk1C-5hk2A:
33.7		 6dk1C-5hk2A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i67 PHOSPHOENOLPYRUVATE
CARBOXYKINASE [GTP]

(Mycobacterium
tuberculosis) 		PF00821
(PEPCK_C)
PF17297
(PEPCK_N) 		5 VAL A 345
ALA A 320
TRP A 355
LEU A  61
THR A 391
 None
 1.16A 6dk1C-5i67A:
undetectable		 6dk1C-5i67A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jbo BETA-GLUCOSIDASE

(Trichoderma
harzianum) 		PF00232
(Glyco_hydro_1) 		5 VAL A 452
ALA A 433
LEU A  69
THR A  18
ALA A 435
 None
 1.42A 6dk1C-5jboA:
undetectable		 6dk1C-5jboA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lun 2-OXOGLUTARATE-DEPEN
DENT
ETHYLENE/SUCCINATE-F
ORMING ENZYME

(Pseudomonas
savastanoi) 		PF03171
(2OG-FeII_Oxy)
PF14226
(DIOX_N) 		5 ALA A 281
TYR A 318
ASP A  91
GLU A  84
THR A  97
 OGA  A 402 ( 3.7A)
None
ARG  A 403 ( 4.7A)
ARG  A 403 (-3.5A)
None
 1.22A 6dk1C-5lunA:
4.3		 6dk1C-5lunA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o16 AMBC

(Sorangium
cellulosum) 		no annotation 5 VAL A 259
ALA A 217
LEU A 270
TRP A 242
ALA A 220
 None
 1.28A 6dk1C-5o16A:
undetectable		 6dk1C-5o16A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica) 		PF01663
(Phosphodiest) 		5 VAL A 157
ALA A 282
TRP A 200
THR A 275
ALA A 279
 None
 1.40A 6dk1C-5tj3A:
undetectable		 6dk1C-5tj3A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7w APYRASE

(Trifolium
repens) 		PF01150
(GDA1_CD39) 		5 TYR A  23
ASP A  37
GLU A  39
THR A 138
ALA A 395
 None
 1.33A 6dk1C-5u7wA:
undetectable		 6dk1C-5u7wA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w70 L-GLUTAMINE:2-DEOXY-
SCYLLO-INOSOSE
AMINOTRANSFERASE

(Streptomyces
ribosidificus) 		PF01041
(DegT_DnrJ_EryC1) 		5 VAL A 121
TYR A 150
LEU A 149
THR A 390
ALA A 386
 None
 1.41A 6dk1C-5w70A:
undetectable		 6dk1C-5w70A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cg0 V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1

(Mus musculus) 		no annotation 5 VAL A 620
ALA A 660
LEU A 711
GLU A 714
THR A 669
 None
 0.87A 6dk1C-6cg0A:
undetectable		 6dk1C-6cg0A:
undetectable