SIMILAR PATTERNS OF AMINO ACIDS FOR 6DJZ_C_GMJC301_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bev | BOVINE ENTEROVIRUSCOAT PROTEINS VP1 TOVP4BOVINE ENTEROVIRUSCOAT PROTEINS VP1 TOVP4 (Enterovirus E;Enterovirus E) |
PF00073(Rhv)PF00073(Rhv) | 4 | TRP 1 111LEU 3 94ASP 3 234GLN 1 104 | None | 1.43A | 6djzC-1bev1:0.6 | 6djzC-1bev1:24.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c7j | PROTEIN(PARA-NITROBENZYLESTERASE) (Bacillussubtilis) |
PF00135(COesterase) | 4 | LEU A 401TYR A 118GLN A 162GLU A 188 | None | 1.31A | 6djzC-1c7jA:undetectable | 6djzC-1c7jA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dwa | MYROSINASE MA1 (Sinapis alba) |
PF00232(Glyco_hydro_1) | 4 | TRP M 100LEU M 232TYR M 152GLN M 146 | NoneNoneNoneGOL M 933 (-3.4A) | 1.31A | 6djzC-1dwaM:undetectable | 6djzC-1dwaM:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6v | METHYL-COENZYME MREDUCTASE I ALPHASUBUNITMETHYL-COENZYME MREDUCTASE I BETASUBUNIT (Methanopyruskandleri;Methanopyruskandleri) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N)PF02241(MCR_beta)PF02783(MCR_beta_N) | 4 | LEU A 469TYR B 191ASP B 229GLN B 221 | None | 1.32A | 6djzC-1e6vA:undetectable | 6djzC-1e6vA:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hmd | HEMERYTHRIN (Themistedyscritum) |
no annotation | 4 | TRP A 97LEU A 56ASP A 106GLU A 58 | NoneNoneFEO A 115 (-2.6A)FEO A 115 (-2.5A) | 1.39A | 6djzC-1hmdA:undetectable | 6djzC-1hmdA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j0h | NEOPULLULANASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 4 | TRP A 160LEU A 175TYR A 457GLN A 482 | None | 1.21A | 6djzC-1j0hA:3.0 | 6djzC-1j0hA:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jf5 | ALPHA AMYLASE II (Thermoactinomycesvulgaris) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 4 | TRP A 156LEU A 172TYR A 454GLN A 479 | None | 1.29A | 6djzC-1jf5A:2.3 | 6djzC-1jf5A:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kkr | 3-METHYLASPARTATEAMMONIA-LYASE (Citrobacteramalonaticus) |
PF05034(MAAL_N)PF07476(MAAL_C) | 4 | LEU A 245TYR A 74ASP A 238GLN A 172 | NoneNone MG A 501 ( 2.6A)2AS A 801 (-3.1A) | 1.20A | 6djzC-1kkrA:0.9 | 6djzC-1kkrA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qon | ACETYLCHOLINESTERASE (Drosophilamelanogaster) |
PF00135(COesterase) | 4 | LEU A 479TYR A 162GLN A 211GLU A 237 | NoneNoneNoneI40 A 997 (-4.2A) | 1.42A | 6djzC-1qonA:undetectable | 6djzC-1qonA:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t8q | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE,PERIPLASMIC (Escherichiacoli) |
PF03009(GDPD) | 4 | LEU A 215TYR A 313ASP A 65GLU A 171 | NoneGOL A1605 (-3.8A) MG A1601 ( 2.7A) MG A1601 ( 2.9A) | 1.06A | 6djzC-1t8qA:undetectable | 6djzC-1t8qA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wyt | GLYCINEDEHYDROGENASE(DECARBOXYLATING)SUBUNIT 1 (Thermusthermophilus) |
PF02347(GDC-P) | 4 | LEU A 214TYR A 163ASP A 233GLN A 256 | None | 1.49A | 6djzC-1wytA:undetectable | 6djzC-1wytA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ddx | BETA-1,3-XYLANASE (Vibrio sp. AX-4) |
no annotation | 4 | LEU A 297TYR A 267ASP A 289GLN A 275 | None | 1.47A | 6djzC-2ddxA:undetectable | 6djzC-2ddxA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e3z | BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF00232(Glyco_hydro_1) | 4 | TRP A 82LEU A 203TYR A 134GLN A 128 | None | 1.25A | 6djzC-2e3zA:undetectable | 6djzC-2e3zA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eae | ALPHA-FUCOSIDASE (Bifidobacteriumbifidum) |
PF14498(Glyco_hyd_65N_2) | 4 | LEU A 534TYR A 520ASP A 689GLN A 781 | NoneNone CA A 902 (-2.9A)None | 1.49A | 6djzC-2eaeA:undetectable | 6djzC-2eaeA:14.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eae | ALPHA-FUCOSIDASE (Bifidobacteriumbifidum) |
PF14498(Glyco_hyd_65N_2) | 4 | LEU A 779TYR A 520GLN A 512GLU A 777 | None | 1.44A | 6djzC-2eaeA:undetectable | 6djzC-2eaeA:14.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hyx | PROTEIN DIPZ (Mycobacteriumtuberculosis) |
PF00578(AhpC-TSA) | 4 | TRP A 508TYR A 469GLN A 441GLU A 570 | None | 1.31A | 6djzC-2hyxA:2.6 | 6djzC-2hyxA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iss | GLUTAMINEAMIDOTRANSFERASESUBUNIT PDXT (Thermotogamaritima) |
PF01174(SNO) | 4 | LEU D 179ASP D 11GLN D 9GLU D 172 | None | 1.34A | 6djzC-2issD:undetectable | 6djzC-2issD:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lpu | KMATG10 (Kluyveromycesmarxianus) |
PF03987(Autophagy_act_C) | 4 | LEU A 17TYR A 7ASP A 29GLN A 31 | None | 1.29A | 6djzC-2lpuA:undetectable | 6djzC-2lpuA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2otd | GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE (Shigellaflexneri) |
PF03009(GDPD) | 4 | LEU A 153TYR A 213ASP A 41GLU A 114 | NonePO4 A 301 (-4.0A)PO4 A 301 (-3.8A)PO4 A 301 (-3.4A) | 0.95A | 6djzC-2otdA:undetectable | 6djzC-2otdA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oz8 | MLL7089 PROTEIN (Mesorhizobiumjaponicum) |
PF13378(MR_MLE_C) | 4 | LEU A 268TYR A 134ASP A 194GLU A 222 | None | 1.48A | 6djzC-2oz8A:undetectable | 6djzC-2oz8A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p3x | POLYPHENOL OXIDASE,CHLOROPLAST (Vitis vinifera) |
PF00264(Tyrosinase)PF12142(PPO1_DWL) | 4 | LEU A 131TYR A 122GLN A 37GLU A 308 | None | 1.34A | 6djzC-2p3xA:undetectable | 6djzC-2p3xA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p76 | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Staphylococcusaureus) |
PF03009(GDPD) | 4 | LEU A 213TYR A 277ASP A 89GLU A 169 | NoneGOL A 501 ( 4.2A) NA A 401 (-2.6A) NA A 401 ( 3.0A) | 1.13A | 6djzC-2p76A:undetectable | 6djzC-2p76A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjj | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Novosphingobiumaromaticivorans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | TRP A 402LEU A 317ASP A 237GLU A 262 | NoneNone MG A1001 ( 4.6A) MG A1001 (-2.5A) | 1.45A | 6djzC-2qjjA:undetectable | 6djzC-2qjjA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qry | THIAMINE-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli) |
PF13343(SBP_bac_6) | 4 | LEU A 86TYR A 215ASP A 121GLU A 245 | NoneTPS A 400 (-4.3A)NoneTPS A 400 (-3.3A) | 1.45A | 6djzC-2qryA:undetectable | 6djzC-2qryA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vx4 | CELLVIBRIO JAPONICUSMANNANASE CJMAN26C (Cellvibriojaponicus) |
PF02156(Glyco_hydro_26) | 4 | LEU A 186TYR A 261ASP A 252GLN A 60 | None | 1.47A | 6djzC-2vx4A:undetectable | 6djzC-2vx4A:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aiv | BETA-GLUCOSIDASE (Secale cereale) |
PF00232(Glyco_hydro_1) | 4 | TRP A 106LEU A 236TYR A 156GLN A 150 | None | 1.28A | 6djzC-3aivA:undetectable | 6djzC-3aivA:14.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ctt | MALTASE-GLUCOAMYLASE (Homo sapiens) |
PF00088(Trefoil)PF01055(Glyco_hydro_31)PF16863(NtCtMGAM_N) | 4 | LEU A 87TYR A 263GLN A 117GLU A 90 | None | 1.25A | 6djzC-3cttA:1.3 | 6djzC-3cttA:14.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqa | GLUCOAMYLASE (Aspergillusniger) |
PF00723(Glyco_hydro_15) | 4 | LEU A 446ASP A 354GLN A 292GLU A 350 | None | 1.47A | 6djzC-3eqaA:undetectable | 6djzC-3eqaA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fkq | NTRC-LIKE TWO-DOMAINPROTEIN ([Eubacterium]rectale) |
PF13614(AAA_31) | 4 | LEU A 290TYR A 225GLN A 163GLU A 253 | None | 1.50A | 6djzC-3fkqA:undetectable | 6djzC-3fkqA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fxg | RHAMNONATEDEHYDRATASE (Fusariumgraminearum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 291TYR A 166ASP A 221GLU A 247 | NoneNone MG A 501 (-2.8A) MG A 501 (-3.2A) | 1.49A | 6djzC-3fxgA:undetectable | 6djzC-3fxgA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gkb | PUTATIVE ENOYL-COAHYDRATASE (Streptomycesavermitilis) |
PF00378(ECH_1) | 4 | TRP A 186LEU A 268GLN A 155GLU A 142 | None | 1.38A | 6djzC-3gkbA:undetectable | 6djzC-3gkbA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gku | PROBABLE RNA-BINDINGPROTEIN ([Clostridium]symbiosum) |
PF01424(R3H)PF13083(KH_4)PF14804(Jag_N) | 4 | LEU A 167TYR A 139GLN A 115GLU A 174 | None | 1.39A | 6djzC-3gkuA:undetectable | 6djzC-3gkuA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gnr | OS03G0212800 PROTEIN (Oryza sativa) |
PF00232(Glyco_hydro_1) | 4 | TRP A 93LEU A 223TYR A 143GLN A 137 | TRP A 93 ( 0.5A)LEU A 223 ( 0.5A)TYR A 143 ( 1.3A)GLN A 137 ( 0.6A) | 1.39A | 6djzC-3gnrA:undetectable | 6djzC-3gnrA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4y | CATECHOL1,2-DIOXYGENASE (Rhodococcusopacus) |
PF00775(Dioxygenase_C)PF04444(Dioxygenase_N) | 4 | TRP A 154LEU A 91ASP A 80GLU A 84 | None | 1.31A | 6djzC-3i4yA:undetectable | 6djzC-3i4yA:25.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jr1 | PUTATIVEFRUCTOSAMINE-3-KINASE (Histophilussomni) |
PF03881(Fructosamin_kin) | 4 | LEU A 251TYR A 240ASP A 218GLU A 220 | None | 1.36A | 6djzC-3jr1A:undetectable | 6djzC-3jr1A:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ly9 | TRANSCRIPTIONALACTIVATOR CADC (Escherichiacoli) |
no annotation | 4 | LEU A 455TYR A 374ASP A 225GLN A 303 | None | 1.08A | 6djzC-3ly9A:undetectable | 6djzC-3ly9A:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mzn | GLUCARATEDEHYDRATASE (Chromohalobactersalexigens) |
PF13378(MR_MLE_C) | 4 | TRP A 170LEU A 149ASP A 17GLN A 371 | None | 1.45A | 6djzC-3mznA:undetectable | 6djzC-3mznA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n3t | PUTATIVE DIGUANYLATECYCLASE/PHOSPHODIESTERASE (Thiobacillusdenitrificans) |
PF00563(EAL) | 4 | LEU A 613ASP A 646GLN A 670GLU A 616 | None MG A 802 (-2.7A)C2E A 801 (-3.3A) MG A 802 (-3.2A) | 1.37A | 6djzC-3n3tA:undetectable | 6djzC-3n3tA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ptk | BETA-GLUCOSIDASEOS4BGLU12 (Oryza sativa) |
PF00232(Glyco_hydro_1) | 4 | TRP A 92LEU A 224TYR A 144GLN A 138 | None | 1.32A | 6djzC-3ptkA:undetectable | 6djzC-3ptkA:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qsv | MOTHERS AGAINSTDECAPENTAPLEGICHOMOLOG 4 (Mus musculus) |
PF03165(MH1) | 4 | LEU A 43TYR A 117ASP A 52GLU A 53 | None | 1.24A | 6djzC-3qsvA:undetectable | 6djzC-3qsvA:19.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qxf | ENDOGLUCANASE (Escherichiacoli) |
PF01270(Glyco_hydro_8) | 4 | TRP A 221LEU A 97ASP A 116GLU A 55 | None | 1.19A | 6djzC-3qxfA:undetectable | 6djzC-3qxfA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thu | MANDELATE RACEMASE /MUCONATE LACTONIZINGENZYME FAMILYPROTEIN (Sphingomonassp. SKA58) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | TRP A 403LEU A 318ASP A 238GLU A 263 | NoneNone MG A 500 ( 4.5A) MG A 500 ( 2.6A) | 1.48A | 6djzC-3thuA:undetectable | 6djzC-3thuA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u5u | RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE (Rauvolfiaserpentina) |
PF00232(Glyco_hydro_1) | 4 | TRP A 99LEU A 248TYR A 151GLN A 145 | None | 1.28A | 6djzC-3u5uA:undetectable | 6djzC-3u5uA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ucq | AMYLOSUCRASE (Deinococcusgeothermalis) |
PF00128(Alpha-amylase) | 4 | LEU A 334ASP A 284GLN A 252GLU A 326 | NoneGOL A 720 (-3.0A)GOL A 720 ( 4.4A)TRS A 700 (-4.2A) | 1.34A | 6djzC-3ucqA:3.0 | 6djzC-3ucqA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4b | STARVATION SENSINGPROTEIN RSPA (Cellvibriojaponicus) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | TRP A 402LEU A 317ASP A 237GLU A 262 | NoneNone MG A 403 ( 4.6A) MG A 403 ( 2.5A) | 1.46A | 6djzC-3v4bA:undetectable | 6djzC-3v4bA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vcn | MANNONATEDEHYDRATASE (Caulobactervibrioides) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | TRP A 403LEU A 318ASP A 238GLU A 263 | NoneNone MG A 501 ( 4.6A) MG A 501 (-2.5A) | 1.50A | 6djzC-3vcnA:undetectable | 6djzC-3vcnA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wau | 4-O-BETA-D-MANNOSYL-D-GLUCOSEPHOSPHORYLASE (Bacteroidesfragilis) |
PF04041(Glyco_hydro_130) | 4 | TRP A 225LEU A 269GLN A 190GLU A 257 | None | 1.25A | 6djzC-3wauA:undetectable | 6djzC-3wauA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a35 | MITOCHONDRIALENOLASE SUPERFAMILYMEMBER 1 (Homo sapiens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 326TYR A 194ASP A 254GLU A 280 | NoneNone MG A1445 (-2.6A) MG A1445 (-3.0A) | 1.48A | 6djzC-4a35A:undetectable | 6djzC-4a35A:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b9y | ALPHA-GLUCOSIDASE,PUTATIVE, ADG31B (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16338(DUF4968)PF17137(DUF5110) | 4 | LEU A 300TYR A 189ASP A 509GLN A 491 | None | 1.39A | 6djzC-4b9yA:undetectable | 6djzC-4b9yA:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bla | MALTOSE-BINDINGPERIPLASMIC PROTEIN,SUPPRESSOR OF FUSEDHOMOLOG (Escherichiacoli;Homo sapiens) |
PF05076(SUFU)PF12470(SUFU_C)PF13416(SBP_bac_8) | 4 | LEU A 464TYR A 385ASP A 522GLN A 526 | None | 1.41A | 6djzC-4blaA:undetectable | 6djzC-4blaA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cmn | INOSITOLPOLYPHOSPHATE5-PHOSPHATASE OCRL-1 (Homo sapiens) |
PF03372(Exo_endo_phos) | 4 | LEU A 376TYR A 513ASP A 451GLN A 445 | None | 1.50A | 6djzC-4cmnA:undetectable | 6djzC-4cmnA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4csq | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
no annotation | 4 | LEU A 103ASP A 12GLN A 7GLU A 13 | None | 1.44A | 6djzC-4csqA:undetectable | 6djzC-4csqA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4f | MANNONATEDEHYDRATASE (Pectobacteriumcarotovorum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | TRP A 404LEU A 319ASP A 239GLU A 264 | NoneNone MG A 504 (-4.0A) MG A 504 ( 2.5A) | 1.49A | 6djzC-4e4fA:undetectable | 6djzC-4e4fA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdj | N-ACETYLGALACTOSAMINE-6-SULFATASE (Homo sapiens) |
PF00884(Sulfatase)PF14707(Sulfatase_C) | 4 | TRP A 141LEU A 128GLN A 148GLU A 126 | None | 1.41A | 6djzC-4fdjA:undetectable | 6djzC-4fdjA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fi4 | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Caulobacter sp.K31) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | TRP A 403LEU A 318ASP A 238GLU A 263 | NoneNone MG A 501 ( 4.5A) MG A 501 ( 2.5A) | 1.49A | 6djzC-4fi4A:undetectable | 6djzC-4fi4A:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hst | GLUTARYL-7-AMINOCEPHALOSPORANIC ACIDACYLASE ALPHA CHAIN (Pseudomonas) |
PF01804(Penicil_amidase) | 4 | TRP A 149LEU A 161TYR A 121GLN A 62 | None | 1.47A | 6djzC-4hstA:undetectable | 6djzC-4hstA:24.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hyq | PHOSPHOLIPASE A1 (Streptomycesalbidoflavus) |
PF13472(Lipase_GDSL_2) | 4 | LEU A 205TYR A 35ASP A 10GLN A 65 | None | 1.50A | 6djzC-4hyqA:undetectable | 6djzC-4hyqA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ip4 | MANDELATERACEMASE/MUCONATELACTONIZINGENZYME-LIKE PROTEIN (Ruegeria sp.TM1040) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 316TYR A 186ASP A 246GLU A 272 | NoneNone MG A 503 (-2.6A) MG A 503 (-2.9A) | 1.40A | 6djzC-4ip4A:undetectable | 6djzC-4ip4A:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iqr | HEPATOCYTE NUCLEARFACTOR 4-ALPHA (Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4) | 4 | LEU A 329TYR A 319ASP A 273GLU A 276 | None | 1.24A | 6djzC-4iqrA:undetectable | 6djzC-4iqrA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j91 | KTR SYSTEM POTASSIUMUPTAKE PROTEIN A (Bacillussubtilis) |
PF02080(TrkA_C)PF02254(TrkA_N) | 4 | LEU A 162ASP A 138GLN A 134GLU A 218 | None | 1.13A | 6djzC-4j91A:undetectable | 6djzC-4j91A:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jc2 | ASFP504 (Alcyonium) |
PF01353(GFP) | 4 | LEU A 219TYR A 71ASP A 74GLN A 184 | None | 1.34A | 6djzC-4jc2A:undetectable | 6djzC-4jc2A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kws | D-MANNONATEDEHYDRATASE (Chromohalobactersalexigens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | TRP A 405LEU A 320ASP A 240GLU A 265 | NoneNone MG A 501 ( 4.7A) MG A 501 ( 2.5A) | 1.48A | 6djzC-4kwsA:undetectable | 6djzC-4kwsA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kws | D-MANNONATEDEHYDRATASE (Chromohalobactersalexigens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | TRP A 405LEU A 320TYR A 171ASP A 213 | NoneNoneNone MG A 501 (-2.6A) | 1.43A | 6djzC-4kwsA:undetectable | 6djzC-4kwsA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l7z | HPCH/HPAI ALDOLASE (Chloroflexusaurantiacus) |
PF03328(HpcH_HpaI) | 4 | TRP A 272LEU A 96ASP A 61GLU A 60 | None | 1.49A | 6djzC-4l7zA:undetectable | 6djzC-4l7zA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mh0 | RAP GUANINENUCLEOTIDE EXCHANGEFACTOR 4RAS-RELATED PROTEINRAP-1B (Mus musculus;Homo sapiens) |
PF00027(cNMP_binding)PF00617(RasGEF)PF00618(RasGEF_N)PF00071(Ras) | 4 | LEU E 893ASP R 38GLN R 43GLU R 37 | None | 1.25A | 6djzC-4mh0E:1.6 | 6djzC-4mh0E:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nex | ACETYLGLUTAMATEKINASE (Xylellafastidiosa) |
PF04768(NAT) | 4 | TRP A 409LEU A 319TYR A 352GLN A 431 | None | 0.93A | 6djzC-4nexA:undetectable | 6djzC-4nexA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nzr | PROTEIN M TD (Mycoplasmagenitalium) |
no annotation | 4 | LEU M 169TYR M 293ASP M 339GLU M 313 | NoneGOL M 501 ( 2.8A)NoneNone | 1.42A | 6djzC-4nzrM:undetectable | 6djzC-4nzrM:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o8m | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Actinobacillussuccinogenes) |
PF03480(DctP) | 4 | LEU A 95TYR A 147GLN A 36GLU A 73 | None2Q2 A 403 (-4.1A)None2Q2 A 403 (-2.8A) | 1.50A | 6djzC-4o8mA:undetectable | 6djzC-4o8mA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ovj | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Alicyclobacillusacidocaldarius) |
PF13416(SBP_bac_8) | 4 | LEU A 298ASP A 205GLN A 415GLU A 280 | None | 1.27A | 6djzC-4ovjA:undetectable | 6djzC-4ovjA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7o | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE,PUTATIVE (Bacillusanthracis) |
PF03009(GDPD) | 4 | LEU A 195TYR A 280ASP A 72GLU A 152 | NoneGOL A 405 (-3.6A) MG A 401 (-3.0A) MG A 401 ( 3.1A) | 1.16A | 6djzC-4r7oA:undetectable | 6djzC-4r7oA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wu0 | SIMILAR TO YTER(BACILUS SUBTILIS) (Clostridiumacetobutylicum) |
PF07470(Glyco_hydro_88) | 4 | TRP A 204LEU A 19GLN A 250GLU A 344 | None | 1.49A | 6djzC-4wu0A:undetectable | 6djzC-4wu0A:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xmv | AMINOPEPTIDASE N (Escherichiacoli) |
PF01433(Peptidase_M1)PF11940(DUF3458)PF17432(DUF3458_C) | 4 | LEU A 731TYR A 660ASP A 712GLN A 665 | NoneNoneGOL A 913 (-3.4A)None | 1.44A | 6djzC-4xmvA:undetectable | 6djzC-4xmvA:13.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwt | DR2417 (Deinococcusradiodurans) |
PF00753(Lactamase_B)PF07521(RMMBL) | 4 | LEU A 93TYR A 276GLN A 316GLU A 87 | None | 1.46A | 6djzC-4xwtA:undetectable | 6djzC-4xwtA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ygs | HYDROLASE (Thermococcusonnurineus) |
PF13419(HAD_2) | 4 | LEU A 23TYR A 114ASP A 9GLU A 15 | None | 1.42A | 6djzC-4ygsA:undetectable | 6djzC-4ygsA:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z0z | AURONE SYNTHASE (Coreopsisgrandiflora) |
PF00264(Tyrosinase)PF12142(PPO1_DWL) | 4 | LEU A 139TYR A 130GLN A 44GLU A 322 | None | 1.46A | 6djzC-4z0zA:undetectable | 6djzC-4z0zA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zfm | PUTATIVE6-PHOSPHO-BETA-GALACTOBIOSIDASE (Geobacillusstearothermophilus) |
PF00232(Glyco_hydro_1) | 4 | TRP A 85LEU A 203TYR A 135GLN A 129 | None | 1.29A | 6djzC-4zfmA:undetectable | 6djzC-4zfmA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zgv | FERREDOXIN RECEPTOR (Pectobacteriumatrosepticum) |
PF07715(Plug) | 4 | LEU A 600TYR A 459GLN A 478GLU A 586 | None | 1.26A | 6djzC-4zgvA:undetectable | 6djzC-4zgvA:13.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8r | METHYL-COENZYME MREDUCTASE II SUBUNITALPHAMETHYL-COENZYME MREDUCTASE II SUBUNITGAMMA (Methanothermobactermarburgensis;Methanothermobactermarburgensis) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N)PF02241(MCR_beta)PF02783(MCR_beta_N) | 4 | LEU A 468TYR B 190ASP B 228GLN B 220 | None | 1.41A | 6djzC-5a8rA:undetectable | 6djzC-5a8rA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cd6 | TPR-DOMAINCONTAINING PROTEIN (Parabacteroidesdistasonis) |
PF17128(DUF5107) | 4 | LEU A 488TYR A 428ASP A 399GLU A 398 | None | 1.41A | 6djzC-5cd6A:1.0 | 6djzC-5cd6A:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dz7 | POLYKETIDEBIOSYNTHESIS PROTEINPKSE (Bacillussubtilis) |
PF00698(Acyl_transf_1) | 4 | LEU A 234TYR A 62ASP A 101GLN A 30 | None | 1.45A | 6djzC-5dz7A:undetectable | 6djzC-5dz7A:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ej1 | PUTATIVE CELLULOSESYNTHASE (Rhodobactersphaeroides) |
PF00535(Glycos_transf_2)PF03552(Cellulose_synt)PF07238(PilZ) | 4 | LEU A 205ASP A 248GLN A 379GLU A 151 | None | 1.38A | 6djzC-5ej1A:undetectable | 6djzC-5ej1A:15.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fpw | PRO CATHEPSIN B S9 (Trypanosomacongolense) |
PF00112(Peptidase_C1) | 4 | TRP A 27LEU A 256ASP A 252GLN A 21 | None | 1.48A | 6djzC-5fpwA:undetectable | 6djzC-5fpwA:18.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hk2 | SIGMA NON-OPIOIDINTRACELLULARRECEPTOR 1 (Homo sapiens) |
PF04622(ERG2_Sigma1R) | 6 | TRP A 89LEU A 95TYR A 120ASP A 126GLN A 135GLU A 172 | NoneNoneNone61V A 301 (-3.2A)None61V A 301 (-2.9A) | 0.34A | 6djzC-5hk2A:34.1 | 6djzC-5hk2A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5in8 | ARISTOLOCHENESYNTHASE (Aspergillusterreus) |
no annotation | 4 | LEU A 178TYR A 168ASP A 214GLN A 240 | None | 1.45A | 6djzC-5in8A:0.6 | 6djzC-5in8A:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j98 | VP3 (Slow beeparalysis virus) |
PF00073(Rhv) | 4 | LEU C 367TYR C 110ASP C 416GLU C 372 | None | 1.33A | 6djzC-5j98C:undetectable | 6djzC-5j98C:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jr3 | CARMINOMYCIN4-O-METHYLTRANSFERASE DNRK (Streptomycespeucetius) |
PF00891(Methyltransf_2) | 4 | LEU A 302TYR A 342ASP A 287GLN A 334 | None4MU A 402 ( 4.6A)NoneNone | 1.38A | 6djzC-5jr3A:undetectable | 6djzC-5jr3A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k04 | UNCHARACTERIZEDPROTEINN-TERMINALACETYLTRANSFERASE BCOMPLEX SUBUNIT NAT3 (Candidaalbicans;Candidaalbicans) |
PF09797(NatB_MDM20)PF08445(FR47) | 4 | LEU B 123TYR B 57ASP B 21GLN A 436 | COA B 202 (-2.9A)NoneCOA B 202 ( 4.0A)None | 1.34A | 6djzC-5k04B:undetectable | 6djzC-5k04B:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mkg | DIGUANYLATEPHOSPHODIESTERASE (Pseudomonasaeruginosa) |
PF00563(EAL) | 4 | LEU B 127ASP B 160GLN B 184GLU B 130 | None CA B 302 (-2.5A)C2E B 304 (-3.1A) CA B 302 (-3.3A) | 1.38A | 6djzC-5mkgB:undetectable | 6djzC-5mkgB:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mza | ERYTHROCYTE MEMBRANEPROTEIN 1 (PFEMP1) (Plasmodiumfalciparum) |
PF05424(Duffy_binding) | 4 | LEU A 932ASP A 922GLN A 822GLU A 925 | None | 1.26A | 6djzC-5mzaA:undetectable | 6djzC-5mzaA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ogs | WD REPEAT ANDHMG-BOX DNA-BINDINGPROTEIN 1 (Homo sapiens) |
no annotation | 4 | LEU A 440ASP A 534GLN A 531GLU A 502 | None | 1.49A | 6djzC-5ogsA:undetectable | 6djzC-5ogsA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opt | 40S RIBOSOMALPROTEIN S1240S RIBOSOMALPROTEIN S10,PUTATIVE (Trypanosomacruzi;Trypanosomacruzi) |
no annotationno annotation | 4 | LEU i 43TYR n 86ASP n 11GLN n 48 | NoneNone U E1725 ( 3.6A)None | 1.40A | 6djzC-5opti:undetectable | 6djzC-5opti:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oqp | CONDENSIN COMPLEXSUBUNIT 3 (Saccharomycescerevisiae) |
no annotation | 4 | LEU A 724ASP A 771GLN A 841GLU A 726 | None | 1.43A | 6djzC-5oqpA:undetectable | 6djzC-5oqpA:13.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t8v | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF12765(Cohesin_HEAT)PF12830(Nipped-B_C) | 4 | LEU A 501ASP A 583GLN A 447GLU A 508 | None | 1.44A | 6djzC-5t8vA:undetectable | 6djzC-5t8vA:10.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t9c | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Bacillussubtilis) |
PF03009(GDPD) | 4 | LEU E 195TYR E 259ASP E 72GLU E 152 | NoneG3P E 302 (-3.8A) CA E 301 ( 2.9A) CA E 301 ( 3.2A) | 1.13A | 6djzC-5t9cE:undetectable | 6djzC-5t9cE:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u8s | DNA REPLICATIONLICENSING FACTORMCM4 (Saccharomycescerevisiae) |
PF00493(MCM)PF14551(MCM_N)PF17207(MCM_OB) | 4 | LEU 4 544TYR 4 706ASP 4 703GLN 4 797 | None | 1.18A | 6djzC-5u8s4:undetectable | 6djzC-5u8s4:13.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x6o | SERINE/THREONINE-PROTEIN KINASE MEC1 (Saccharomycescerevisiae) |
no annotation | 4 | TRP C1158TYR C1297GLN C1151GLU C1140 | None | 1.48A | 6djzC-5x6oC:undetectable | 6djzC-5x6oC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y4k | DMSP LYASE DDDY (Acinetobacterbereziniae) |
no annotation | 4 | TRP A 315LEU A 355TYR A 262GLN A 294 | None | 1.41A | 6djzC-5y4kA:4.8 | 6djzC-5y4kA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fdf | TRNA(CYTOSINE(38)-C(5))-METHYLTRANSFERASE (Schizosaccharomycespombe) |
no annotation | 4 | TRP A 294LEU A 285TYR A 211GLU A 203 | None | 1.27A | 6djzC-6fdfA:undetectable | 6djzC-6fdfA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6frv | GLUCOAMYLASE (Aspergillusniger) |
no annotation | 4 | LEU A 446ASP A 354GLN A 292GLU A 350 | None | 1.48A | 6djzC-6frvA:undetectable | 6djzC-6frvA:undetectable |