SIMILAR PATTERNS OF AMINO ACIDS FOR 6DJZ_A_GMJA301_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a5z | L-LACTATEDEHYDROGENASE (Thermotogamaritima) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | PHE A 315VAL A 289VAL A 281LEU A 113ALA A 325 | None | 1.19A | 6djzA-1a5zA:undetectable | 6djzA-1a5zA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dbh | PROTEIN (HUMAN SOS1) (Homo sapiens) |
PF00169(PH)PF00621(RhoGEF) | 5 | MET A 538LEU A 541ILE A 461HIS A 460ALA A 528 | None | 1.20A | 6djzA-1dbhA:0.0 | 6djzA-1dbhA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8r | L-AMINO ACID OXIDASE (Calloselasmarhodostoma) |
PF01593(Amino_oxidase) | 5 | LEU A 52ILE A 291VAL A 271LEU A 482ALA A 483 | None | 1.13A | 6djzA-1f8rA:0.0 | 6djzA-1f8rA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fu1 | DNA REPAIR PROTEINXRCC4 (Homo sapiens) |
PF06632(XRCC4) | 5 | LEU A 28ILE A 34LEU A 108ALA A 73TYR A 66 | NoneNoneACY A 501 ( 4.9A)NoneNone | 1.08A | 6djzA-1fu1A:undetectable | 6djzA-1fu1A:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fu1 | DNA REPAIR PROTEINXRCC4 (Homo sapiens) |
PF06632(XRCC4) | 5 | LEU A 28ILE A 34THR A 37LEU A 108TYR A 66 | NoneNoneNoneACY A 501 ( 4.9A)None | 1.24A | 6djzA-1fu1A:undetectable | 6djzA-1fu1A:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8k | ARSENITE OXIDASE (Alcaligenesfaecalis) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | LEU A 403ILE A 231VAL A 418LEU A 360ALA A 363 | None | 1.23A | 6djzA-1g8kA:0.0 | 6djzA-1g8kA:14.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gae | D-GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE (Escherichiacoli) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | ILE O 5VAL O 73VAL O 66ALA O 18TYR O 317 | NoneNoneNoneNoneNAD O 336 ( 3.9A) | 1.09A | 6djzA-1gaeO:undetectable | 6djzA-1gaeO:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ikp | EXOTOXIN A (Pseudomonasaeruginosa) |
PF09009(Exotox-A_cataly)PF09101(Exotox-A_bind)PF09102(Exotox-A_target) | 5 | LEU A 597ILE A 471VAL A 566HIS A 440THR A 442 | None | 1.17A | 6djzA-1ikpA:0.0 | 6djzA-1ikpA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k72 | ENDOGLUCANASE 9G ([Clostridium]cellulolyticum) |
PF00759(Glyco_hydro_9)PF00942(CBM_3) | 5 | LEU A 588PHE A 495VAL A 479THR A 526VAL A 545 | None | 1.21A | 6djzA-1k72A:1.6 | 6djzA-1k72A:15.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l7v | VITAMIN B12TRANSPORTATP-BINDING PROTEINBTUD (Escherichiacoli) |
PF00005(ABC_tran) | 5 | MET C 188LEU C 157ILE C 144PHE C 58VAL C 4 | None | 1.04A | 6djzA-1l7vC:0.0 | 6djzA-1l7vC:24.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lq2 | BETA-D-GLUCANGLUCOHYDROLASEISOENZYME EXO1 (Hordeum vulgare) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 5 | LEU A 406THR A 508VAL A 512LEU A 391ALA A 539 | None | 1.18A | 6djzA-1lq2A:undetectable | 6djzA-1lq2A:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1luj | CATENIN BETA-1 (Homo sapiens) |
PF00514(Arm) | 5 | LEU A 498ILE A 569VAL A 564LEU A 577ALA A 576 | None | 1.21A | 6djzA-1lujA:undetectable | 6djzA-1lujA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m7j | D-AMINOACYLASE (Alcaligenesfaecalis) |
PF07969(Amidohydro_3) | 5 | PHE A 413VAL A 92HIS A 67VAL A 247TYR A 389 | NoneNone ZN A 802 ( 3.2A)NoneNone | 1.07A | 6djzA-1m7jA:undetectable | 6djzA-1m7jA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofe | FERREDOXIN-DEPENDENTGLUTAMATE SYNTHASE 2 (Synechocystissp. PCC 6803) |
PF00310(GATase_2)PF01493(GXGXG)PF01645(Glu_synthase)PF04898(Glu_syn_central) | 5 | TYR A 196LEU A 191ILE A 173LEU A 17ALA A 201 | None | 1.23A | 6djzA-1ofeA:undetectable | 6djzA-1ofeA:9.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oj4 | 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE (Escherichiacoli) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | ILE A 41THR A 55VAL A 57LEU A 74ALA A 70 | None | 1.14A | 6djzA-1oj4A:undetectable | 6djzA-1oj4A:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sbp | SULFATE-BINDINGPROTEIN (Salmonellaenterica) |
PF13531(SBP_bac_11) | 5 | TYR A 242LEU A 243VAL A 229VAL A 52LEU A 16 | None | 1.20A | 6djzA-1sbpA:undetectable | 6djzA-1sbpA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vmi | PUTATIVE PHOSPHATEACETYLTRANSFERASE (Escherichiacoli) |
PF01515(PTA_PTB) | 6 | ILE A 120HIS A 301VAL A 111LEU A 39ALA A 40TYR A 33 | None | 1.40A | 6djzA-1vmiA:undetectable | 6djzA-1vmiA:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xdv | SON OF SEVENLESSPROTEIN HOMOLOG 1 (Homo sapiens) |
PF00169(PH)PF00617(RasGEF)PF00618(RasGEF_N)PF00621(RhoGEF) | 5 | MET A 538LEU A 541ILE A 461HIS A 460ALA A 528 | None | 1.19A | 6djzA-1xdvA:undetectable | 6djzA-1xdvA:14.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zrz | PROTEIN KINASE C,IOTA (Homo sapiens) |
PF00069(Pkinase)PF00433(Pkinase_C) | 5 | LEU A 430ILE A 507VAL A 516LEU A 360ALA A 356 | None | 1.18A | 6djzA-1zrzA:undetectable | 6djzA-1zrzA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2akc | CLASS A NONSPECIFICACID PHOSPHATASEPHON (Salmonellaenterica) |
PF01569(PAP2) | 5 | TYR A 161VAL A 91THR A 100VAL A 229TYR A 116 | None | 1.00A | 6djzA-2akcA:undetectable | 6djzA-2akcA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4m | GLYCOGENPHOSPHORYLASE (Corynebacteriumcallunae) |
PF00343(Phosphorylase) | 5 | MET A 307PHE A 349VAL A 258VAL A 392ALA A 401 | None | 1.19A | 6djzA-2c4mA:undetectable | 6djzA-2c4mA:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ral | SERINE-ASPARTATEREPEAT-CONTAININGPROTEIN G (Staphylococcusepidermidis) |
PF10425(SdrG_C_C) | 5 | LEU A 497PHE A 530VAL A 488VAL A 467TYR A 424 | None | 1.08A | 6djzA-2ralA:undetectable | 6djzA-2ralA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w31 | GLOBIN (Geobactersulfurreducens) |
PF11563(Protoglobin) | 5 | TYR A 82LEU A 86ILE A 138THR A 114VAL A 110 | None | 1.02A | 6djzA-2w31A:undetectable | 6djzA-2w31A:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x2i | ALPHA-1,4-GLUCANLYASE ISOZYME 1 (Gracilariopsislemaneiformis) |
PF01055(Glyco_hydro_31) | 5 | LEU A 344PHE A 138VAL A 79THR A 153VAL A 145 | None | 1.10A | 6djzA-2x2iA:undetectable | 6djzA-2x2iA:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdq | LIGHT-INDEPENDENTPROTOCHLOROPHYLLIDEREDUCTASE SUBUNIT N (Thermosynechococcuselongatus) |
PF00148(Oxidored_nitro) | 5 | LEU A 88ILE A 101VAL A 27LEU A 119TYR A 82 | None | 1.21A | 6djzA-2xdqA:undetectable | 6djzA-2xdqA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8i | PA4872 OXALOACETATEDECARBOXYLASE (Pseudomonasaeruginosa) |
PF13714(PEP_mutase) | 5 | VAL A 210THR A 115LEU A 64ALA A 63TYR A 275 | None | 1.18A | 6djzA-3b8iA:undetectable | 6djzA-3b8iA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c5y | RIBOSE/GALACTOSEISOMERASE (Novosphingobiumaromaticivorans) |
PF02502(LacAB_rpiB)PF12408(DUF3666) | 5 | ILE A 3HIS A 31LEU A 127ALA A 21TYR A 115 | None | 1.17A | 6djzA-3c5yA:undetectable | 6djzA-3c5yA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3m | TRANSCRIPTIONALREGULATOR, LACIFAMILY (Ruegeriapomeroyi) |
PF13377(Peripla_BP_3) | 5 | TYR A 108PHE A 167VAL A 301LEU A 78TYR A 105 | None | 1.23A | 6djzA-3e3mA:undetectable | 6djzA-3e3mA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3en0 | CYANOPHYCINASE (Synechocystissp. PCC 6803) |
PF03575(Peptidase_S51) | 5 | LEU A 184PHE A 207VAL A 166VAL A 213LEU A 248 | None | 1.19A | 6djzA-3en0A:undetectable | 6djzA-3en0A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3etc | AMP-BINDING PROTEIN (Methanosarcinaacetivorans) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | LEU A 163ILE A 127VAL A 147THR A 119ALA A 134 | None | 1.15A | 6djzA-3etcA:undetectable | 6djzA-3etcA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fdg | DIPEPTIDASE AC.METALLO PEPTIDASE.MEROPS FAMILY M19 (Rhodobactersphaeroides) |
PF01244(Peptidase_M19) | 5 | MET A 134LEU A 157ILE A 142LEU A 95ALA A 94 | None | 1.12A | 6djzA-3fdgA:undetectable | 6djzA-3fdgA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3io1 | AMINOBENZOYL-GLUTAMATE UTILIZATIONPROTEIN (Klebsiellapneumoniae) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | PHE A 179VAL A 39VAL A 115LEU A 4ALA A 424 | None | 1.21A | 6djzA-3io1A:undetectable | 6djzA-3io1A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3isp | HTH-TYPETRANSCRIPTIONALREGULATORRV1985C/MT2039 (Mycobacteriumtuberculosis) |
PF00126(HTH_1)PF03466(LysR_substrate) | 5 | ILE A 97PHE A 110VAL A 124VAL A 113ALA A 279 | None | 1.15A | 6djzA-3ispA:undetectable | 6djzA-3ispA:24.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3isp | HTH-TYPETRANSCRIPTIONALREGULATORRV1985C/MT2039 (Mycobacteriumtuberculosis) |
PF00126(HTH_1)PF03466(LysR_substrate) | 5 | ILE A 97THR A 284VAL A 113LEU A 135ALA A 100 | None | 1.20A | 6djzA-3ispA:undetectable | 6djzA-3ispA:24.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j09 | COPPER-EXPORTINGP-TYPE ATPASE A (Archaeoglobusfulgidus) |
PF00122(E1-E2_ATPase)PF00403(HMA)PF00702(Hydrolase) | 5 | VAL A 280HIS A 462VAL A 487LEU A 450ALA A 453 | None | 1.16A | 6djzA-3j09A:1.8 | 6djzA-3j09A:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jap | EIF3A (Saccharomycescerevisiae) |
PF00411(Ribosomal_S11) | 5 | LEU o 408ILE o 390VAL o 432LEU o 330TYR o 416 | None | 1.23A | 6djzA-3japo:undetectable | 6djzA-3japo:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mud | DNA REPAIR PROTEINXRCC4,TROPOMYOSINALPHA-1 CHAIN (Gallus gallus;Homo sapiens) |
PF06632(XRCC4) | 5 | LEU A 28ILE A 34LEU A 108ALA A 73TYR A 66 | None | 1.00A | 6djzA-3mudA:undetectable | 6djzA-3mudA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q4f | DNA REPAIR PROTEINXRCC4 (Homo sapiens) |
PF06632(XRCC4) | 5 | LEU C 28ILE C 34LEU C 108ALA C 73TYR C 66 | None | 1.18A | 6djzA-3q4fC:undetectable | 6djzA-3q4fC:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ren | GLYCOSYL HYDROLASE,FAMILY 8 (Clostridiumperfringens) |
PF01270(Glyco_hydro_8) | 5 | LEU A 312ILE A 327PHE A 280LEU A 363TYR A 92 | NoneNoneNoneNoneEDO A 373 (-4.8A) | 1.22A | 6djzA-3renA:undetectable | 6djzA-3renA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rof | LOW MOLECULAR WEIGHTPROTEIN-TYROSINE-PHOSPHATASE PTPA (Staphylococcusaureus) |
PF01451(LMWPc) | 5 | ILE A 142PHE A 6VAL A 83ALA A 149TYR A -3 | None | 1.06A | 6djzA-3rofA:undetectable | 6djzA-3rofA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t5t | PUTATIVEGLYCOSYLTRANSFERASE (Streptomyceshygroscopicus) |
PF00982(Glyco_transf_20) | 5 | LEU A 30ILE A 80VAL A 45LEU A 84ALA A 52 | None | 1.23A | 6djzA-3t5tA:undetectable | 6djzA-3t5tA:17.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqp | ENOLASE (Coxiellaburnetii) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | MET A 144LEU A 404ILE A 375THR A 347VAL A 351 | None | 1.18A | 6djzA-3tqpA:undetectable | 6djzA-3tqpA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w03 | DNA REPAIR PROTEINXRCC4 (Homo sapiens) |
PF06632(XRCC4) | 5 | LEU C 28ILE C 34LEU C 108ALA C 73TYR C 66 | None | 1.08A | 6djzA-3w03C:undetectable | 6djzA-3w03C:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w03 | DNA REPAIR PROTEINXRCC4 (Homo sapiens) |
PF06632(XRCC4) | 5 | LEU C 28ILE C 34THR C 37LEU C 108TYR C 66 | None | 1.24A | 6djzA-3w03C:undetectable | 6djzA-3w03C:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3we9 | PUTATIVEPHYTOENE/SQUALENESYNTHASE YISP (Bacillussubtilis) |
PF00494(SQS_PSY) | 5 | ILE A 248HIS A 253THR A 202LEU A 216ALA A 212 | None | 1.04A | 6djzA-3we9A:undetectable | 6djzA-3we9A:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wec | CYTOCHROME P450 (Rhodococcuserythropolis) |
PF00067(p450) | 5 | ILE A 286PHE A 269VAL A 344LEU A 132ALA A 135 | None | 1.22A | 6djzA-3wecA:undetectable | 6djzA-3wecA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zk4 | DIPHOSPHONUCLEOTIDEPHOSPHATASE 1 (Lupinus luteus) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 5 | LEU A 550ILE A 431VAL A 422LEU A 504TYR A 500 | None | 1.02A | 6djzA-3zk4A:undetectable | 6djzA-3zk4A:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a9w | MONOOXYGENASE (Stenotrophomonasmaltophilia) |
PF13738(Pyr_redox_3) | 5 | ILE A 125VAL A 317VAL A 111LEU A 91TYR A 85 | None | 1.13A | 6djzA-4a9wA:undetectable | 6djzA-4a9wA:24.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aco | CENTROMEREDNA-BINDING PROTEINCOMPLEX CBF3 SUBUNITA (Saccharomycescerevisiae) |
PF16787(NDC10_II) | 5 | TYR A 332LEU A 324PHE A 205VAL A 345LEU A 226 | None | 1.16A | 6djzA-4acoA:undetectable | 6djzA-4acoA:12.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ce7 | UNSATURATED3S-RHAMNOGLYCURONYLHYDROLASE (Nonlabensulvanivorans) |
PF07470(Glyco_hydro_88) | 5 | LEU A 352ILE A 26LEU A 70ALA A 69TYR A 99 | None | 1.24A | 6djzA-4ce7A:undetectable | 6djzA-4ce7A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4chc | POLYMERASE ACIDICPROTEIN (Thogotothogotovirus) |
no annotation | 5 | LEU A 100ILE A 41VAL A 12LEU A 149ALA A 148 | None | 1.18A | 6djzA-4chcA:undetectable | 6djzA-4chcA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dsh | UDP-GALACTOPYRANOSEMUTASE (Trypanosomacruzi) |
PF01593(Amino_oxidase)PF13450(NAD_binding_8) | 5 | PHE A 248VAL A 254HIS A 34THR A 229ALA A 21 | None | 1.13A | 6djzA-4dshA:undetectable | 6djzA-4dshA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f4h | GLUTAMINE DEPENDENTNAD+ SYNTHETASE (Burkholderiathailandensis) |
PF00795(CN_hydrolase)PF02540(NAD_synthase) | 5 | LEU A 84ILE A 164VAL A 168LEU A 46ALA A 45 | None | 1.02A | 6djzA-4f4hA:undetectable | 6djzA-4f4hA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gji | L-RHAMNOSE ISOMERASE (Pseudomonasstutzeri) |
no annotation | 5 | TYR A 199LEU A 200HIS A 220LEU A 216ALA A 249 | None | 1.22A | 6djzA-4gjiA:undetectable | 6djzA-4gjiA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gnk | 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATEPHOSPHODIESTERASEBETA-3 (Homo sapiens) |
PF00168(C2)PF00387(PI-PLC-Y)PF00388(PI-PLC-X)PF09279(EF-hand_like) | 5 | VAL B 823THR B 842VAL B 730LEU B 791ALA B 792 | None | 1.23A | 6djzA-4gnkB:undetectable | 6djzA-4gnkB:10.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ii2 | UBIQUITIN-CONJUGATING ENZYME E2 4 (Schizosaccharomycespombe) |
PF00179(UQ_con) | 5 | LEU C 103ILE C 54VAL C 26HIS C 55LEU C 86 | None | 1.16A | 6djzA-4ii2C:undetectable | 6djzA-4ii2C:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4keg | MALTOSE-BINDINGPERIPLASMIC/PALATELUNG AND NASALEPITHELIUM CLONEFUSION PROTEIN (Escherichiacoli;Homo sapiens) |
PF01273(LBP_BPI_CETP)PF13416(SBP_bac_8) | 5 | LEU A1234ILE A1163PHE A1252VAL A1253LEU A1059 | None | 1.21A | 6djzA-4kegA:undetectable | 6djzA-4kegA:18.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p5w | CALCIUM-BINDINGMITOCHONDRIALCARRIER PROTEINARALAR2,CALCIUM-BINDING MITOCHONDRIALCARRIER PROTEINARALAR2 (Homo sapiens) |
no annotation | 5 | ILE A 650PHE A 99THR A 119VAL A 115LEU A 45 | None | 1.10A | 6djzA-4p5wA:undetectable | 6djzA-4p5wA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pc9 | C4-DICARBOXYLATETRANSPORT SYSTEM,SUBSTRATE-BINDINGPROTEIN, PUTATIVE (Roseobacterdenitrificans) |
PF03480(DctP) | 5 | LEU A 215ILE A 91VAL A 66LEU A 273ALA A 42 | CS2 A 401 (-4.2A)NoneNoneNoneNone | 1.18A | 6djzA-4pc9A:undetectable | 6djzA-4pc9A:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pk1 | CHIMERA PROTEIN OFOUTER MEMBRANEPROTEIN ASSEMBLYFACTORS BAMA ANDBAMB (Escherichiacoli) |
PF07244(POTRA)PF13360(PQQ_2) | 5 | LEU A1063VAL A1162THR A1145VAL A1147ALA A1109 | None | 1.22A | 6djzA-4pk1A:undetectable | 6djzA-4pk1A:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qfu | GLYCOSIDE HYDROLASEFAMILY 5 (Bacteroidesvulgatus) |
PF12904(Collagen_bind_2)PF13204(DUF4038) | 5 | TYR A 75ILE A 327HIS A 324VAL A 305ALA A 82 | None | 1.08A | 6djzA-4qfuA:2.9 | 6djzA-4qfuA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qj4 | 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATEPHOSPHODIESTERASEBETA-3 (Homo sapiens) |
PF00168(C2)PF00387(PI-PLC-Y)PF00388(PI-PLC-X)PF09279(EF-hand_like) | 5 | LEU B 685VAL B 823THR B 842VAL B 730LEU B 791 | None | 1.05A | 6djzA-4qj4B:undetectable | 6djzA-4qj4B:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rjk | ACETOLACTATESYNTHASE (Bacillussubtilis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | LEU A 96PHE A 156VAL A 152VAL A 30ALA A 64 | None | 1.03A | 6djzA-4rjkA:undetectable | 6djzA-4rjkA:17.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr2 | SUBTILISIN-LIKE 1SERINE PROTEASE (Plasmodiumvivax) |
PF00082(Peptidase_S8) | 5 | ILE A 558VAL A 562LEU A 503ALA A 527TYR A 511 | None | 1.12A | 6djzA-4tr2A:undetectable | 6djzA-4tr2A:14.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4upi | SULFATASE FAMILYPROTEIN (Ruegeriapomeroyi) |
PF00884(Sulfatase) | 5 | TYR A 23LEU A 20ILE A 354PHE A 309ALA A 327 | None | 1.11A | 6djzA-4upiA:undetectable | 6djzA-4upiA:17.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zd6 | HALOHYDRIN EPOXIDASEB (Corynebacteriumsp.) |
PF13561(adh_short_C2) | 5 | ILE A 90PHE A 158VAL A 115LEU A 82ALA A 130 | None | 1.16A | 6djzA-4zd6A:undetectable | 6djzA-4zd6A:24.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zi5 | P91 (metagenome) |
PF01738(DLH) | 5 | PHE A 182VAL A 178THR A 139VAL A 159ALA A 132 | None | 1.15A | 6djzA-4zi5A:undetectable | 6djzA-4zi5A:23.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a60 | INORGANICTRIPHOSPHATASE (Escherichiacoli) |
PF01928(CYTH) | 5 | LEU A 313HIS A 263THR A 373LEU A 225ALA A 228 | None | 1.20A | 6djzA-5a60A:undetectable | 6djzA-5a60A:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b5x | LIMITINGCO2-INDUCIBLEPROTEIN LCIC (Chlamydomonasreinhardtii) |
no annotation | 5 | LEU A 343HIS A 297VAL A 127LEU A 82ALA A 88 | None | 1.15A | 6djzA-5b5xA:undetectable | 6djzA-5b5xA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bn4 | V-TYPE ATP SYNTHASEALPHA CHAIN (Nanoarchaeumequitans) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N)PF16886(ATP-synt_ab_Xtn) | 5 | LEU A 207ILE A 376VAL A 398THR A 322VAL A 379 | None | 1.24A | 6djzA-5bn4A:undetectable | 6djzA-5bn4A:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cfa | BONESIALOPROTEIN-BINDINGPROTEIN (Staphylococcusaureus) |
PF10425(SdrG_C_C) | 5 | LEU A 230PHE A 264VAL A 221VAL A 191TYR A 148 | None | 1.21A | 6djzA-5cfaA:undetectable | 6djzA-5cfaA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5chx | XRCC4-MYH7-1590-1657 (Homo sapiens) |
PF01576(Myosin_tail_1)PF06632(XRCC4) | 5 | LEU A 28ILE A 34LEU A 108ALA A 73TYR A 66 | NoneNoneMLY A 99 ( 4.5A)MLY A 72 ( 3.6A)None | 1.07A | 6djzA-5chxA:undetectable | 6djzA-5chxA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cj0 | XRCC4-MYH7-(1631-1692) CHIMERA PROTEIN (Homo sapiens) |
PF06632(XRCC4) | 5 | LEU A 28ILE A 34LEU A 108ALA A 73TYR A 66 | None | 1.11A | 6djzA-5cj0A:undetectable | 6djzA-5cj0A:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cj4 | XRCC4-MYH7-(1562-1622) CHIMERA PROTEIN (Homo sapiens) |
PF06632(XRCC4) | 5 | LEU A 28ILE A 34LEU A 108ALA A 73TYR A 66 | NoneNoneMLY A 99 ( 4.8A)MLY A 72 ( 3.6A)None | 1.12A | 6djzA-5cj4A:undetectable | 6djzA-5cj4A:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5clw | 1,4-ALPHA-GLUCAN-BRANCHING ENZYME (Homo sapiens) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C)PF02922(CBM_48) | 5 | LEU A 663THR A 640VAL A 638ALA A 692TYR A 657 | None | 1.13A | 6djzA-5clwA:undetectable | 6djzA-5clwA:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dfw | SINGLE CHAIN FVFRAGMENT (Mus musculus) |
PF07686(V-set) | 5 | TYR H 602LEU H 612PHE H 152HIS H 199LEU H 598 | None | 0.98A | 6djzA-5dfwH:undetectable | 6djzA-5dfwH:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e44 | FNR REGULATOR (Aliivibriofischeri) |
PF00027(cNMP_binding)PF13545(HTH_Crp_2) | 5 | LEU A 239ILE A 231PHE A 181THR A 194LEU A 214 | None | 1.19A | 6djzA-5e44A:3.8 | 6djzA-5e44A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5foi | MYCINAMICIN VIII C21METHYL HYDROXYLASE (Micromonosporagriseorubida) |
PF00067(p450) | 5 | ILE A 273HIS A 271THR A 242LEU A 136ALA A 135 | None | 1.24A | 6djzA-5foiA:undetectable | 6djzA-5foiA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h05 | AMYP (marinemetagenome) |
PF00128(Alpha-amylase) | 5 | LEU A 390PHE A 258VAL A 437VAL A 254LEU A 58 | None | 1.22A | 6djzA-5h05A:undetectable | 6djzA-5h05A:16.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hk2 | SIGMA NON-OPIOIDINTRACELLULARRECEPTOR 1 (Homo sapiens) |
PF04622(ERG2_Sigma1R) | 6 | ILE A 124PHE A 133VAL A 152HIS A 154THR A 160ALA A 86 | 61V A 301 ( 4.7A)NoneNone61V A 301 ( 4.1A)NoneNone | 1.00A | 6djzA-5hk2A:34.9 | 6djzA-5hk2A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hk2 | SIGMA NON-OPIOIDINTRACELLULARRECEPTOR 1 (Homo sapiens) |
PF04622(ERG2_Sigma1R) | 9 | MET A 93LEU A 105PHE A 133VAL A 152HIS A 154THR A 160VAL A 162LEU A 186ALA A 185 | 61V A 301 (-3.4A)NoneNoneNone61V A 301 ( 4.1A)NoneNoneNone61V A 301 ( 4.2A) | 1.49A | 6djzA-5hk2A:34.9 | 6djzA-5hk2A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hk2 | SIGMA NON-OPIOIDINTRACELLULARRECEPTOR 1 (Homo sapiens) |
PF04622(ERG2_Sigma1R) | 12 | MET A 93TYR A 103LEU A 105ILE A 124PHE A 133VAL A 152HIS A 154THR A 160VAL A 162LEU A 182ALA A 185TYR A 206 | 61V A 301 (-3.4A)61V A 301 ( 4.3A)None61V A 301 ( 4.7A)NoneNone61V A 301 ( 4.1A)NoneNoneNone61V A 301 ( 4.2A)61V A 301 (-3.6A) | 0.58A | 6djzA-5hk2A:34.9 | 6djzA-5hk2A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hk2 | SIGMA NON-OPIOIDINTRACELLULARRECEPTOR 1 (Homo sapiens) |
PF04622(ERG2_Sigma1R) | 6 | PHE A 133VAL A 152HIS A 154THR A 160LEU A 186ALA A 86 | NoneNone61V A 301 ( 4.1A)NoneNoneNone | 0.95A | 6djzA-5hk2A:34.9 | 6djzA-5hk2A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihe | DNA POLYMERASE IISMALL SUBUNIT (Pyrococcusabyssi) |
PF00149(Metallophos) | 5 | LEU A 435ILE A 358VAL A 396LEU A 374TYR A 177 | None | 1.06A | 6djzA-5iheA:undetectable | 6djzA-5iheA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irm | UNCHARACTERIZEDPROTEIN (Oryctolaguscuniculus) |
PF05729(NACHT)PF13516(LRR_6) | 5 | TYR A 232HIS A 293THR A 357VAL A 402TYR A 435 | ADP A1101 (-3.4A)NoneNoneNoneADP A1101 (-4.6A) | 1.23A | 6djzA-5irmA:undetectable | 6djzA-5irmA:12.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ko9 | EMBRYONIC STEMCELL-SPECIFIC5-HYDROXYMETHYLCYTOSINE-BINDING PROTEIN (Homo sapiens) |
PF02586(SRAP) | 5 | LEU A 238ILE A 179THR A 94LEU A 217ALA A 215 | None | 1.13A | 6djzA-5ko9A:undetectable | 6djzA-5ko9A:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lw6 | DDB_G0293866 (Dictyosteliumdiscoideum) |
no annotation | 5 | LEU A 129THR A 210VAL A 155LEU A 107ALA A 23 | None | 1.20A | 6djzA-5lw6A:undetectable | 6djzA-5lw6A:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ol0 | PUTATIVE SILENTINFORMATIONREGULATOR 2,PUTATIVESILENT INFORMATIONREGULATOR 2 (Leishmaniainfantum) |
no annotation | 5 | LEU A 93ILE A 126HIS A 144ALA A 73TYR A 87 | None | 0.99A | 6djzA-5ol0A:undetectable | 6djzA-5ol0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opj | RHAMNOGALACTURONANLYASE (Bacteroidesthetaiotaomicron) |
no annotation | 5 | ILE A 313HIS A 381THR A 340VAL A 394LEU A 332 | None | 1.14A | 6djzA-5opjA:undetectable | 6djzA-5opjA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5td7 | ZGC:55652 (Danio rerio) |
PF00850(Hist_deacetyl) | 5 | MET A 13PHE A 97VAL A 95VAL A 74ALA A 109 | None | 1.20A | 6djzA-5td7A:undetectable | 6djzA-5td7A:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u4h | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Acinetobacterbaumannii) |
PF00275(EPSP_synthase) | 5 | ILE A 39THR A 70VAL A 44LEU A 78TYR A 105 | None | 1.20A | 6djzA-5u4hA:undetectable | 6djzA-5u4hA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u4h | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Acinetobacterbaumannii) |
PF00275(EPSP_synthase) | 5 | LEU A 195PHE A 159VAL A 157LEU A 222ALA A 175 | None | 1.15A | 6djzA-5u4hA:undetectable | 6djzA-5u4hA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u7n | CYTOCHROME C OXIDASESUBUNIT 2 (Thermusthermophilus) |
no annotation | 5 | ILE A 103PHE A 116VAL A 135THR A 121VAL A 118 | None | 1.16A | 6djzA-5u7nA:undetectable | 6djzA-5u7nA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wj7 | DNA REPAIR PROTEINXRCC4,MYOSIN-7 (Homo sapiens) |
PF06632(XRCC4) | 5 | LEU A 28ILE A 34LEU A 108ALA A 73TYR A 66 | None | 1.22A | 6djzA-5wj7A:undetectable | 6djzA-5wj7A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wlz | DNA REPAIR PROTEINXRCC4,MYOSIN-7 (Homo sapiens) |
no annotation | 5 | LEU C 28ILE C 34LEU C 108ALA C 73TYR C 66 | None | 1.18A | 6djzA-5wlzC:undetectable | 6djzA-5wlzC:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xt3 | PHOSPHODIESTERASEACTING ON CYCLICDINUCLEOTIDES (Staphylococcusaureus) |
no annotation | 5 | LEU A 394ILE A 351THR A 465VAL A 469LEU A 525 | None | 0.95A | 6djzA-5xt3A:undetectable | 6djzA-5xt3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yap | SCYLLO-INOSITOLDEHYDROGENASE WITHL-GLUCOSEDEHYDROGENASEACTIVITY (Paracoccuslaeviglucosivorans) |
no annotation | 5 | ILE A 357PHE A 372VAL A 210LEU A 263TYR A 135 | NoneNoneNoneNone8S0 A 402 (-4.5A) | 0.95A | 6djzA-5yapA:undetectable | 6djzA-5yapA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bnf | PHOSPHOETHANOLAMINETRANSFERASE (Moraxella sp.HMSC061H09) |
no annotation | 5 | ILE A 343PHE A 560VAL A 351VAL A 267TYR A 331 | None | 1.10A | 6djzA-6bnfA:undetectable | 6djzA-6bnfA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dd6 | PHOTOLYASE PHRB (Agrobacteriumtumefaciens) |
no annotation | 5 | LEU A 12PHE A 83VAL A 34VAL A 109TYR A 271 | NoneDLZ A 602 (-4.2A)DLZ A 602 (-4.6A)NoneNone | 1.09A | 6djzA-6dd6A:undetectable | 6djzA-6dd6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gsa | - (-) |
no annotation | 5 | TYR E 332LEU E 324PHE E 205VAL E 345LEU E 226 | None | 1.16A | 6djzA-6gsaE:undetectable | 6djzA-6gsaE:undetectable |