SIMILAR PATTERNS OF AMINO ACIDS FOR 6CJK_B_ACTB302

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ad0 ANTIBODY A5B7 (HEAVY
CHAIN)

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B  59
GLY B  65
THR B  68
 None
 0.19A 6cjkB-1ad0B:
26.4		 6cjkB-1ad0B:
61.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1axt IMMUNOGLOBULIN IGG2A

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.15A 6cjkB-1axtH:
24.8		 6cjkB-1axtH:
58.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1f4w ANTIBODY S-20-4, FAB
FRAGMENT, HEAVY
CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  60
GLY H  66
THR H  69
 None
 0.19A 6cjkB-1f4wH:
23.0		 6cjkB-1f4wH:
56.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1h0d ANTIBODY FAB
FRAGMENT, HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B  59
GLY B  65
THR B  68
 None
 0.10A 6cjkB-1h0dB:
24.9		 6cjkB-1h0dB:
58.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1i9i RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.15A 6cjkB-1i9iH:
25.9		 6cjkB-1i9iH:
57.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1igj IGG2A-KAPPA 26-10
FAB (HEAVY CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B  59
GLY B  65
THR B  68
 None
 0.16A 6cjkB-1igjB:
15.7		 6cjkB-1igjB:
54.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ohq IMMUNOGLOBULIN

(Homo sapiens) 		PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.17A 6cjkB-1ohqA:
18.4		 6cjkB-1ohqA:
58.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5a EP-CADHERIN

(Mus musculus) 		PF00028
(Cadherin) 		3 TYR A 471
GLY A 437
THR A 468
 None
CA  A 914 ( 4.0A)
None
 0.00A 6cjkB-1q5aA:
undetectable		 6cjkB-1q5aA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rjc CAMELID HEAVY CHAIN
ANTIBODY

(Camelus
dromedarius) 		PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.17A 6cjkB-1rjcA:
18.0		 6cjkB-1rjcA:
29.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s3k HU3S193 FAB
FRAGMENT, HEAVY
CHAIN

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  60
GLY H  66
THR H  69
 None
 0.19A 6cjkB-1s3kH:
25.2		 6cjkB-1s3kH:
61.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1shm ANTIBODY RIG

(Lama glama) 		PF07686
(V-set) 		3 TYR A  59
GLY A  65
THR A  68
 None
 0.08A 6cjkB-1shmA:
20.3		 6cjkB-1shmA:
35.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sjx IMMUNOGLOBULIN VH
DOMAIN

(Lama glama) 		PF07686
(V-set) 		3 TYR A 859
GLY A 865
THR A 868
 None
 0.19A 6cjkB-1sjxA:
19.9		 6cjkB-1sjxA:
28.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1t66 IMMUNOGLOBULIN HEAVY
CHAIN

(Mus musculus) 		no annotation 3 TYR H  62
GLY H  68
THR H  71
 None
 0.19A 6cjkB-1t66H:
24.7		 6cjkB-1t66H:
58.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wz1 IG HEAVY CHAIN

(Mus musculus) 		PF07686
(V-set) 		3 TYR H  62
GLY H  68
THR H  71
 None
 0.19A 6cjkB-1wz1H:
20.0		 6cjkB-1wz1H:
43.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9q 4M5.3
ANTI-FLUORESCEIN
SINGLE CHAIN
ANTIBODY FRAGMENT

(Homo sapiens) 		PF07686
(V-set) 		3 TYR A 213
GLY A 219
THR A 222
 None
 0.11A 6cjkB-1x9qA:
19.3		 6cjkB-1x9qA:
25.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1xfp HEAVY CHAIN ANTIBODY

(Camelus
dromedarius) 		PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.10A 6cjkB-1xfpA:
18.0		 6cjkB-1xfpA:
31.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zvy IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN

(Camelus
dromedarius) 		PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.17A 6cjkB-1zvyA:
19.6		 6cjkB-1zvyA:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2a77 IMMUNOGLOBULIN HEAVY
CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  60
GLY H  66
THR H  69
 None
 0.18A 6cjkB-2a77H:
24.6		 6cjkB-2a77H:
56.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2b2x ANTIBODY AQC2 FAB

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.14A 6cjkB-2b2xH:
25.7		 6cjkB-2b2xH:
62.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2uud NQ10-1.12 ANTI-PHOX
ANTIBODY

(Mus musculus) 		PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.18A 6cjkB-2uudH:
20.1		 6cjkB-2uudH:
57.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xxm CAMELID VHH 9

(Vicugna pacos) 		PF07686
(V-set) 		3 TYR B  59
GLY B  65
THR B  68
 None
 0.16A 6cjkB-2xxmB:
17.5		 6cjkB-2xxmB:
28.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ypv FAB 12C1

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  60
GLY H  66
THR H  69
 None
 0.19A 6cjkB-2ypvH:
22.7		 6cjkB-2ypvH:
52.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3b9v HEAVY CHAIN VARIABLE
DOMAIN

(Homo sapiens) 		PF07686
(V-set) 		3 TYR A  59
GLY A  65
THR A  68
 None
 0.09A 6cjkB-3b9vA:
20.0		 6cjkB-3b9vA:
61.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3c2a FAB 447-52D HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.19A 6cjkB-3c2aH:
20.6		 6cjkB-3c2aH:
59.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fzu IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN

(Homo sapiens) 		no annotation 3 TYR H  62
GLY H  68
THR H  71
 None
 0.16A 6cjkB-3fzuH:
25.0		 6cjkB-3fzuH:
59.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g9a MINIMIZER

(Camelus
dromedarius) 		PF07686
(V-set) 		3 TYR B  59
GLY B  65
THR B  68
 None
 0.18A 6cjkB-3g9aB:
18.0		 6cjkB-3g9aB:
34.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ghe FAB 537-10D, HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.17A 6cjkB-3gheH:
19.9		 6cjkB-3gheH:
58.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3i9g SONEPCIZUMAB
ANTIBODY FAB
FRAGMENT, HEAVY
CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.16A 6cjkB-3i9gH:
23.8		 6cjkB-3i9gH:
54.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ntc FAB HEAVY CHAIN

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.19A 6cjkB-3ntcH:
24.2		 6cjkB-3ntcH:
53.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3nzh 5F6 HEAVY CHAIN

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  63
GLY H  69
THR H  72
 None
 0.15A 6cjkB-3nzhH:
23.7		 6cjkB-3nzhH:
60.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p9w HUMAN VEGF

(Homo sapiens) 		PF07686
(V-set) 		3 TYR B  59
GLY B  65
THR B  68
 TYR  B  59 ( 1.3A)
GLY  B  65 ( 0.0A)
THR  B  68 ( 0.8A)
 0.12A 6cjkB-3p9wB:
18.7		 6cjkB-3p9wB:
37.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qyc VH DOMAIN OF IGG
MOLECULE

(Homo sapiens) 		PF07686
(V-set) 		3 TYR A  62
GLY A  68
THR A  71
 None
 0.19A 6cjkB-3qycA:
19.1		 6cjkB-3qycA:
34.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tpk IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN KW1

(Camelidae) 		PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.14A 6cjkB-3tpkA:
19.3		 6cjkB-3tpkA:
34.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3zhk MG2X1 SCAFFOLD
ANTIBODY

(Homo sapiens) 		PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.12A 6cjkB-3zhkA:
20.5		 6cjkB-3zhkA:
36.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3zks XA4813

(Lama glama) 		PF07686
(V-set) 		3 TYR D 219
GLY D 225
THR D 228
 None
 0.18A 6cjkB-3zksD:
19.4		 6cjkB-3zksD:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4b41 ANTIBODY G7

(Lama glama) 		PF07686
(V-set) 		3 TYR A  59
GLY A  65
THR A  68
 None
 0.13A 6cjkB-4b41A:
19.0		 6cjkB-4b41A:
35.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4b50 2H10 LLAMA VHH

(Lama glama) 		PF07686
(V-set) 		3 TYR A  59
GLY A  65
THR A  68
 None
 0.17A 6cjkB-4b50A:
19.5		 6cjkB-4b50A:
38.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4c57 NANOBODY

(Lama glama) 		PF07686
(V-set) 		3 TYR C  67
GLY C  74
THR C  77
 None
 0.18A 6cjkB-4c57C:
17.0		 6cjkB-4c57C:
35.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dgy HCV1 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.16A 6cjkB-4dgyH:
23.5		 6cjkB-4dgyH:
60.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4dka SINGLE DOMAIN
ANTIBODY VHH

(Lama glama) 		PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.11A 6cjkB-4dkaA:
18.3		 6cjkB-4dkaA:
35.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ej1 NB113 CAMELID
ANTIBODY FRAGMENT

(Lama glama) 		PF07686
(V-set) 		3 TYR C  60
GLY C  66
THR C  69
 None
 0.14A 6cjkB-4ej1C:
19.5		 6cjkB-4ej1C:
34.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4f58 HEAVY CHAIN OF FAB
OF A NEUTRALIZING
ANTIBODY L3

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 SO4  H 301 (-4.2A)
None
SO4  H 301 ( 4.3A)
 0.14A 6cjkB-4f58H:
19.9		 6cjkB-4f58H:
61.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fql MONOCLONAL ANTIBODY
CR8033 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.17A 6cjkB-4fqlH:
24.7		 6cjkB-4fqlH:
60.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4grw NANOBODY 37D5

(Lama glama) 		PF07686
(V-set) 		3 TYR F  60
GLY F  66
THR F  69
 None
 0.16A 6cjkB-4grwF:
17.4		 6cjkB-4grwF:
51.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hdi IG HEAVY CHAIN V
REGION RF, IG
GAMMA-3 CHAIN C
REGION

(Mus musculus) 		no annotation 3 TYR H  60
GLY H  66
THR H  69
 None
 0.16A 6cjkB-4hdiH:
24.6		 6cjkB-4hdiH:
56.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hem ANTI-BASEPLATE
TP901-1 LLAMA VHH 02

(Lama glama) 		PF07686
(V-set) 		3 TYR E  60
GLY E  66
THR E  69
 None
 0.14A 6cjkB-4hemE:
18.6		 6cjkB-4hemE:
34.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i0c CABHUL5 ANTIBODY

(Camelus
dromedarius) 		PF07686
(V-set) 		3 TYR C  58
GLY C  64
THR C  67
 None
 0.12A 6cjkB-4i0cC:
19.1		 6cjkB-4i0cC:
29.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4jo3 MONOCLONAL
ANTI-HIV-1 GP120 V3
ANTIBODY R20 HEAVY
CHAIN

(Oryctolagus
cuniculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.10A 6cjkB-4jo3H:
27.7		 6cjkB-4jo3H:
84.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4kfz ANTI-LMO2 VH

(Homo sapiens) 		PF07686
(V-set) 		3 TYR C  60
GLY C  66
THR C  69
 None
 0.12A 6cjkB-4kfzC:
18.5		 6cjkB-4kfzC:
60.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4kml NANOBODY

(Lama glama) 		PF07686
(V-set) 		3 TYR B  60
GLY B  66
THR B  69
 None
 0.15A 6cjkB-4kmlB:
19.3		 6cjkB-4kmlB:
31.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4krm NANOBODY/VHH DOMAIN
7D12

(Lama glama) 		PF07686
(V-set) 		3 TYR B  60
GLY B  66
THR B  69
 None
 0.17A 6cjkB-4krmB:
19.5		 6cjkB-4krmB:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4krn NANOBODY/VHH DOMAIN
EGA1

(Lama glama) 		PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.19A 6cjkB-4krnA:
19.2		 6cjkB-4krnA:
34.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4kvc IG HEAVY CHAIN V
REGION MOPC 21, IGH
PROTEIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  60
GLY H  66
THR H  69
 None
 0.15A 6cjkB-4kvcH:
25.0		 6cjkB-4kvcH:
61.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgr CAMELID NANOBODY
(VHH3)

(Vicugna pacos) 		PF07686
(V-set) 		3 TYR B  59
GLY B  65
THR B  68
 None
 0.14A 6cjkB-4lgrB:
19.1		 6cjkB-4lgrB:
29.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lrn GEP 1 HEAVY CHAIN

(Homo sapiens) 		PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.16A 6cjkB-4lrnH:
18.2		 6cjkB-4lrnH:
31.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4m3k CAMELID HEAVY-CHAIN
ANTIBODY VARIABLE
FRAGMENT CAB-H7S

(Lama glama) 		PF07686
(V-set) 		3 TYR B  59
GLY B  65
THR B  68
 None
 0.17A 6cjkB-4m3kB:
16.8		 6cjkB-4m3kB:
31.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4mqt NANOBODY 9-8

(Lama glama) 		PF07686
(V-set) 		3 TYR B  63
GLY B  69
THR B  72
 None
 0.12A 6cjkB-4mqtB:
19.2		 6cjkB-4mqtB:
48.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4nbz A26.8 VHH

(Lama glama) 		PF07686
(V-set) 		3 TYR B  60
GLY B  66
THR B  69
 None
 0.19A 6cjkB-4nbzB:
18.5		 6cjkB-4nbzB:
32.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nc1 A26.8 VHH

(Lama glama) 		PF07686
(V-set) 		3 TYR E  60
GLY E  66
THR E  69
 None
 0.15A 6cjkB-4nc1E:
19.1		 6cjkB-4nc1E:
29.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4o5l FAB F045-092 HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.19A 6cjkB-4o5lH:
23.6		 6cjkB-4o5lH:
53.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ocl NB1

(Lama glama) 		PF07686
(V-set) 		3 TYR C  61
GLY C  67
THR C  70
 None
 0.11A 6cjkB-4oclC:
19.3		 6cjkB-4oclC:
29.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ocr CAP256-VRC26.01
HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.19A 6cjkB-4ocrH:
19.3		 6cjkB-4ocrH:
53.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4pb0 AB53 HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
None
CL  H 305 ( 4.6A)
 0.15A 6cjkB-4pb0H:
24.6		 6cjkB-4pb0H:
60.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r90 ANTI CD70 LLAMA
GLAMA FAB 27B3 HEAVY
CHAIN

(Lama glama) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  60
GLY H  66
THR H  69
 None
 0.11A 6cjkB-4r90H:
19.4		 6cjkB-4r90H:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r96 LLAMA GLAMA FAB 48A2
AGAINST HUMAN CMET H
CHAIN

(Lama glama) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B  60
GLY B  66
THR B  69
 None
 0.19A 6cjkB-4r96B:
24.1		 6cjkB-4r96B:
53.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4rav SINGLE-CHAIN FV, VH

(Homo sapiens) 		PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.16A 6cjkB-4ravA:
20.2		 6cjkB-4ravA:
46.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4rgn 14G8 HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B  59
GLY B  65
THR B  68
 None
 0.12A 6cjkB-4rgnB:
25.2		 6cjkB-4rgnB:
56.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4tvs VHH DOMAIN BS-1

(Vicugna pacos) 		PF05609
(LAP1C) 		3 TYR a  61
GLY a  67
THR a  70
 None
 0.15A 6cjkB-4tvsa:
19.1		 6cjkB-4tvsa:
32.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4u6v FAB, ANTIGEN BINDING
FRAGMENT, HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 SO4  H 301 (-4.3A)
None
None
 0.14A 6cjkB-4u6vH:
24.0		 6cjkB-4u6vH:
60.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4uom FAB FRAGMENT HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  60
GLY H  66
THR H  69
 None
 0.16A 6cjkB-4uomH:
25.2		 6cjkB-4uomH:
54.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4uu9 MEDI7814

(Homo sapiens) 		PF07686
(V-set) 		3 TYR A  59
GLY A  65
THR A  68
 None
 0.14A 6cjkB-4uu9A:
20.5		 6cjkB-4uu9A:
58.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4w6x NANOBODY NBFEDF7

(Lama glama) 		PF07686
(V-set) 		3 TYR B  59
GLY B  66
THR B  69
 None
 0.12A 6cjkB-4w6xB:
19.0		 6cjkB-4w6xB:
34.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4w6y NANOBODY NBFEDF9

(Lama glama) 		PF07686
(V-set) 		3 TYR B  60
GLY B  66
THR B  69
 None
 0.19A 6cjkB-4w6yB:
19.9		 6cjkB-4w6yB:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4weu ANTI-F4+ETEC
BACTERIA VHH
VARIABLE REGION

(Lama glama) 		PF07686
(V-set) 		3 TYR D 860
GLY D 866
THR D 869
 None
 0.12A 6cjkB-4weuD:
20.0		 6cjkB-4weuD:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wht HEAVY CHAIN OF THE
FAB FRAGMENT DERIVED
FROM NEUTRALIZING
ANTIBODY 3/11

(Rattus
norvegicus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.19A 6cjkB-4whtA:
23.5		 6cjkB-4whtA:
52.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xvj ANTIBODY HEAVY CHAIN
VARIABLE DOMAIN

(Homo sapiens) 		PF07686
(V-set) 		3 TYR H  60
GLY H  66
THR H  69
 None
 0.18A 6cjkB-4xvjH:
19.9		 6cjkB-4xvjH:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4y5v DIABODY 305 VH
DOMAIN

(Homo sapiens) 		PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.12A 6cjkB-4y5vA:
20.3		 6cjkB-4y5vA:
43.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4y8d NANOBODY

(Lama glama) 		PF07686
(V-set) 		3 TYR C  57
GLY C  63
THR C  66
 None
EDO  C 202 (-4.3A)
EDO  C 202 (-4.0A)
 0.16A 6cjkB-4y8dC:
17.8		 6cjkB-4y8dC:
32.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ybq ANTIBODY FV FRAGMENT
HEAVY CHAIN

(Mus musculus) 		PF07686
(V-set) 		3 TYR D  61
GLY D  67
THR D  70
 None
 0.19A 6cjkB-4ybqD:
20.5		 6cjkB-4ybqD:
42.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4yhp FAB HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR A  60
GLY A  66
THR A  69
 None
 0.16A 6cjkB-4yhpA:
25.5		 6cjkB-4yhpA:
61.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4z9k VHH2(F5) ANTIBODY

(Vicugna pacos) 		PF07686
(V-set) 		3 TYR B  58
GLY B  64
THR B  67
 None
 0.19A 6cjkB-4z9kB:
16.3		 6cjkB-4z9kB:
31.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4zpt D12 FAB HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR A  59
GLY A  65
THR A  68
 None
 0.14A 6cjkB-4zptA:
26.0		 6cjkB-4zptA:
61.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5b3n ANTI-H4K20ME1_SCFV

(Mus musculus) 		PF07686
(V-set) 		3 TYR A  62
GLY A  68
THR A  71
 None
 0.20A 6cjkB-5b3nA:
19.9		 6cjkB-5b3nA:
37.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5b6f ANTI-LEUKOTRIENE C4
MONOCLONAL ANTIBODY
IMMUNOGLOBULIN
GAMMA1 HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B  81
GLY B  87
THR B  90
 None
 0.14A 6cjkB-5b6fB:
25.2		 6cjkB-5b6fB:
31.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5c2b SCFV 3B4 HEAVY CHAIN

(Homo sapiens) 		PF07686
(V-set) 		3 TYR H  60
GLY H  66
THR H  69
 None
 0.15A 6cjkB-5c2bH:
19.6		 6cjkB-5c2bH:
36.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5c6w PROTEIN
IGHV1-69-2,IG LAMBDA
CHAIN V-II REGION
NIG-84

(Homo sapiens) 		PF07686
(V-set) 		3 TYR H  60
GLY H  66
THR H  69
 None
 0.17A 6cjkB-5c6wH:
18.8		 6cjkB-5c6wH:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d1z Y10 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B  61
GLY B  67
THR B  70
 None
 0.18A 6cjkB-5d1zB:
22.9		 6cjkB-5d1zB:
60.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d9q NIH45-46 SINGLE
CHAIN FV

(Homo sapiens) 		PF07686
(V-set) 		3 TYR D  59
GLY D  65
THR D  68
 None
 0.00A 6cjkB-5d9qD:
undetectable		 6cjkB-5d9qD:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dlm HEAVY CHAIN OF
MONOCLONAL ANTIBODY

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  59
GLY H  65
THR H  68
 None
 0.15A 6cjkB-5dlmH:
25.2		 6cjkB-5dlmH:
58.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5do2 4C2 HEAVY CHAIN

(Mus musculus) 		no annotation 3 TYR H  60
GLY H  66
THR H  69
 None
 0.13A 6cjkB-5do2H:
25.5		 6cjkB-5do2H:
58.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dr5 ABD09097 FAB HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR H  60
GLY H  66
THR H  69
 None
 0.16A 6cjkB-5dr5H:
24.3		 6cjkB-5dr5H:
58.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dxw PD-L1 NANOBODY

(Mus musculus) 		PF07686
(V-set) 		3 TYR A  62
GLY A  68
THR A  71
 None
 0.17A 6cjkB-5dxwA:
19.2		 6cjkB-5dxwA:
32.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5f1k NANOBODY MU1053

(Lama glama) 		PF07686
(V-set) 		3 TYR C  60
GLY C  66
THR C  69
 None
 0.14A 6cjkB-5f1kC:
20.4		 6cjkB-5f1kC:
33.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5f1o NANOBODY MU551

(Lama glama) 		PF07686
(V-set) 		3 TYR B  60
GLY B  66
THR B  69
 None
 0.17A 6cjkB-5f1oB:
19.4		 6cjkB-5f1oB:
32.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5gs1 DIABODY

(Homo sapiens) 		PF07686
(V-set) 		3 TYR C  59
GLY C  65
THR C  68
 None
 0.18A 6cjkB-5gs1C:
19.6		 6cjkB-5gs1C:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hgg CAMELID DERIVED
ANTIBODY FRAGMENT,
NB4

(Vicugna pacos) 		PF07686
(V-set) 		3 TYR S  60
GLY S  66
THR S  69
 None
 0.17A 6cjkB-5hggS:
18.7		 6cjkB-5hggS:
35.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5hm1 LAMA VHH ANTIBODY
2E7

(Lama glama) 		PF07686
(V-set) 		3 TYR A  59
GLY A  65
THR A  68
 None
 0.18A 6cjkB-5hm1A:
17.4		 6cjkB-5hm1A:
52.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5j1s VHH DOMAIN BS-2

(Vicugna pacos) 		PF07686
(V-set) 		3 TYR C  60
GLY C  66
THR C  69
 None
 0.16A 6cjkB-5j1sC:
19.3		 6cjkB-5j1sC:
51.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5j56 VHH SINGLE CHAIN
ANTIBODY V1C7

(Vicugna pacos) 		PF07686
(V-set) 		3 TYR B  64
GLY B  70
THR B  73
 None
 0.16A 6cjkB-5j56B:
18.1		 6cjkB-5j56B:
53.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ja9 NANOBODY 6

(Lama glama) 		PF07686
(V-set) 		3 TYR A  61
GLY A  67
THR A  70
 None
 0.20A 6cjkB-5ja9A:
19.2		 6cjkB-5ja9A:
30.97