SIMILAR PATTERNS OF AMINO ACIDS FOR 6CIF_D_H4BD502_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5j | ACONITATE HYDRATASE2 (Escherichiacoli) |
PF00330(Aconitase)PF06434(Aconitase_2_N)PF11791(Aconitase_B_N) | 4 | TRP A 155PHE A 156GLU A 154ARG A 340 | None | 1.34A | 6cifC-1l5jA:0.06cifD-1l5jA:0.0 | 6cifC-1l5jA:7.086cifD-1l5jA:7.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d52 | PENTAKETIDE CHROMONESYNTHASE (Aloearborescens) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | PHE A 83GLU A 87VAL A 52ARG A 81 | None | 1.34A | 6cifC-2d52A:0.66cifD-2d52A:0.0 | 6cifC-2d52A:12.326cifD-2d52A:12.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d9j | REGULATOR OFG-PROTEIN SIGNALLING7 (Homo sapiens) |
PF00615(RGS) | 4 | PHE A 123GLU A 30VAL A 27TRP A 15 | None | 1.28A | 6cifC-2d9jA:0.06cifD-2d9jA:0.0 | 6cifC-2d9jA:18.316cifD-2d9jA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e9f | ARGININOSUCCINATELYASE (Thermusthermophilus) |
PF00206(Lyase_1)PF14698(ASL_C2) | 4 | PHE A 221GLU A 218ARG A 123TRP A 37 | None | 1.43A | 6cifC-2e9fA:0.06cifD-2e9fA:0.0 | 6cifC-2e9fA:11.496cifD-2e9fA:11.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i9u | CYTOSINE/GUANINEDEAMINASE RELATEDPROTEIN (Clostridiumacetobutylicum) |
PF01979(Amidohydro_1) | 4 | PHE A 99GLU A 101ARG A 202TRP A 93 | NoneNoneGUN A 503 (-3.7A)None | 1.29A | 6cifC-2i9uA:0.06cifD-2i9uA:0.0 | 6cifC-2i9uA:8.806cifD-2i9uA:8.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inc | TOLUENE, O-XYLENEMONOOXYGENASEOXYGENASE SUBUNIT (Pseudomonasstutzeri) |
PF02332(Phenol_Hydrox)PF04945(YHS) | 4 | PHE A 29GLU A 27VAL A 23ARG A 116 | None | 1.23A | 6cifC-2incA:0.06cifD-2incA:0.0 | 6cifC-2incA:8.096cifD-2incA:8.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qlu | ACTIVIN RECEPTORTYPE IIB (Homo sapiens) |
PF00069(Pkinase) | 4 | PHE A 381GLU A 368VAL A 369ARG A 320 | None | 1.37A | 6cifC-2qluA:0.06cifD-2qluA:0.0 | 6cifC-2qluA:13.566cifD-2qluA:13.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qqo | NEUROPILIN-2 (Homo sapiens) |
PF00431(CUB)PF00754(F5_F8_type_C) | 4 | TRP A 372PHE A 406GLU A 370ARG A 405 | None | 1.46A | 6cifC-2qqoA:0.16cifD-2qqoA:0.3 | 6cifC-2qqoA:11.346cifD-2qqoA:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ckb | SUSD (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB) | 4 | TRP A 485PHE A 489GLU A 484ARG A 437 | None | 0.97A | 6cifC-3ckbA:0.06cifD-3ckbA:0.0 | 6cifC-3ckbA:11.086cifD-3ckbA:11.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1n | E3 UBIQUITIN-PROTEINLIGASE HUWE1 (Homo sapiens) |
PF00632(HECT) | 4 | PHE A4109GLU A4033VAL A4019TRP A4065 | None | 1.30A | 6cifC-3g1nA:undetectable6cifD-3g1nA:0.0 | 6cifC-3g1nA:10.576cifD-3g1nA:10.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nk2 | HEMOGLOBIN-LIKEPROTEIN (Methylacidiphiluminfernorum) |
PF01152(Bac_globin) | 4 | PHE A 191GLU A 186VAL A 182TRP A 159 | None | 1.04A | 6cifC-4nk2A:0.06cifD-4nk2A:undetectable | 6cifC-4nk2A:19.136cifD-4nk2A:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6x | ANKYRIN-3 (Homo sapiens) |
PF00531(Death) | 4 | PHE A 28GLU A 25VAL A 71ARG A 58 | None | 1.20A | 6cifC-4o6xA:undetectable6cifD-4o6xA:undetectable | 6cifC-4o6xA:16.246cifD-4o6xA:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3v | POLYKETIDE SYNTHASEPKSR (Bacillussubtilis) |
PF14765(PS-DH) | 4 | TRP A 140PHE A 144GLU A 139VAL A 19 | None | 1.09A | 6cifC-4u3vA:0.06cifD-4u3vA:0.0 | 6cifC-4u3vA:13.106cifD-4u3vA:13.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bv9 | CELLULOSE1,4-BETA-CELLOBIOSIDASE (Bacilluspumilus) |
PF02011(Glyco_hydro_48) | 4 | TRP A 185PHE A 640GLU A 186ARG A 644 | NoneNone CA A 801 (-2.3A)None | 1.25A | 6cifC-5bv9A:0.06cifD-5bv9A:undetectable | 6cifC-5bv9A:8.316cifD-5bv9A:8.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cow | PUTATIVEUNCHARACTERIZEDPROTEIN (Caenorhabditisremanei) |
no annotation | 4 | TRP A 407PHE A 404GLU A 410VAL A 409 | None | 1.36A | 6cifC-5cowA:undetectable6cifD-5cowA:undetectable | 6cifC-5cowA:13.256cifD-5cowA:13.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ft6 | CYSTEINE DESULFURASECSDA (Escherichiacoli) |
PF00266(Aminotran_5) | 4 | TRP A 288PHE A 13GLU A 33VAL A 36 | None | 1.45A | 6cifC-5ft6A:0.66cifD-5ft6A:undetectable | 6cifC-5ft6A:12.376cifD-5ft6A:12.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hh9 | PVDN (Pseudomonasaeruginosa) |
PF00266(Aminotran_5) | 4 | PHE A 367GLU A 246VAL A 245TRP A 265 | None | 1.46A | 6cifC-5hh9A:0.06cifD-5hh9A:undetectable | 6cifC-5hh9A:12.536cifD-5hh9A:12.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jse | PHIAB6 TAILSPIKE (unidentifiedphage) |
PF12708(Pectate_lyase_3) | 4 | TRP A 347PHE A 290VAL A 341TRP A 323 | None | 1.15A | 6cifC-5jseA:undetectable6cifD-5jseA:undetectable | 6cifC-5jseA:7.636cifD-5jseA:7.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lp8 | E3 UBIQUITIN-PROTEINLIGASE HUWE1 (Homo sapiens) |
no annotation | 4 | PHE B4109GLU B4033VAL B4019TRP B4065 | None | 1.20A | 6cifC-5lp8B:undetectable6cifD-5lp8B:undetectable | 6cifC-5lp8B:10.226cifD-5lp8B:10.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m7r | PROTEIN O-GLCNACASE (Homo sapiens) |
PF07555(NAGidase) | 4 | TRP A 73PHE A 318GLU A 317ARG A 84 | None | 1.48A | 6cifC-5m7rA:undetectable6cifD-5m7rA:undetectable | 6cifC-5m7rA:6.456cifD-5m7rA:6.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 4 | TRP A 414PHE A 411GLU A 413ARG A 225 | None | 1.05A | 6cifC-5m8tA:0.06cifD-5m8tA:undetectable | 6cifC-5m8tA:10.726cifD-5m8tA:10.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5no8 | BACCELL_00875 (Bacteroidescellulosilyticus) |
no annotation | 4 | TRP A 599PHE A 606VAL A 538ARG A 205 | None | 1.48A | 6cifC-5no8A:0.06cifD-5no8A:undetectable | 6cifC-5no8A:8.386cifD-5no8A:8.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | 40S RIBOSOMALPROTEIN S5-B,PUTATIVEUNCHARACTERIZEDPROTEIN (Trichomonasvaginalis;Trichomonasvaginalis) |
PF00177(Ribosomal_S7)PF00333(Ribosomal_S5)PF03719(Ribosomal_S5_C) | 4 | PHE F 50GLU c 51VAL c 16ARG F 49 | NoneNoneNone C 21421 ( 4.4A) | 0.96A | 6cifC-5xyiF:undetectable6cifD-5xyiF:undetectable | 6cifC-5xyiF:16.326cifD-5xyiF:16.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6az1 | RIBOSOMAL PROTEIN S7RIBOSOMAL PROTEINS28E (Leishmaniadonovani;Leishmaniadonovani) |
no annotationno annotation | 4 | PHE H 47GLU d 69VAL d 29ARG H 46 | NoneNoneNone G 12036 ( 3.6A) | 1.22A | 6cifC-6az1H:undetectable6cifD-6az1H:undetectable | 6cifC-6az1H:20.226cifD-6az1H:20.22 |