SIMILAR PATTERNS OF AMINO ACIDS FOR 6CEN_A_SAMA1301_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)

Filter list by:

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1id0	PHOQ HISTIDINE KINASE (Escherichia coli)	PF02518 (HATPase_c)	5	GLY A 443 ASN A 389 TYR A 393 TYR A 355 LEU A 351	MG A 700 ( 4.4A) ANP A 487 (-3.0A) ANP A 487 (-4.0A) None None	1.19A	6cenA-1id0A: 0.0	6cenA-1id0A: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1mvh	CRYPTIC LOCI REGULATOR 4 (Schizosaccharomyces pombe)	PF00856 (SET) PF05033 (Pre-SET)	5	GLY A 339 TRP A 340 TYR A 381 ASN A 409 HIS A 410	None	0.40A	6cenA-1mvhA: 17.6	6cenA-1mvhA: 27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1peg	HISTONE H3 METHYLTRANSFERASE DIM-5 (Neurospora crassa)	PF00856 (SET) PF05033 (Pre-SET)	10	ARG A 159 GLY A 160 TRP A 161 TYR A 204 ASN A 241 HIS A 242 TYR A 283 CYH A 306 CYH A 308 LEU A 317	None SAH A 319 ( 4.6A) SAH A 319 (-4.8A) SAH A 319 (-4.0A) SAH A 319 (-3.6A) SAH A 319 (-4.3A) SAH A 319 (-4.7A) ZN A 4 ( 2.3A) ZN A 4 (-2.2A) SAH A 319 (-3.9A)	0.84A	6cenA-1pegA: 19.9	6cenA-1pegA: 29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1peg	HISTONE H3 METHYLTRANSFERASE DIM-5 (Neurospora crassa)	PF00856 (SET) PF05033 (Pre-SET)	6	ARG A 159 TRP A 161 ASN A 241 HIS A 242 TYR A 283 CYH A 308	None SAH A 319 (-4.8A) SAH A 319 (-3.6A) SAH A 319 (-4.3A) SAH A 319 (-4.7A) ZN A 4 (-2.2A)	1.49A	6cenA-1pegA: 19.9	6cenA-1pegA: 29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1r76	PECTATE LYASE (Niveispirillum irakense)	PF09492 (Pec_lyase)	5	GLY A 217 TRP A 218 TYR A 55 ASN A 215 LEU A 299	None None None HG A4000 (-3.4A) None	1.47A	6cenA-1r76A: undetectable	6cenA-1r76A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1we5	PUTATIVE FAMILY 31 GLUCOSIDASE YICI (Escherichia coli)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	5	GLY A 159 ASN A 175 ASN A 203 TYR A 163 CYH A 601	None	1.43A	6cenA-1we5A: undetectable	6cenA-1we5A: 13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2cb3	PEPTIDOGLYCAN-RECOGN ITION PROTEIN-LE (Drosophila melanogaster)	PF01510 (Amidase_2)	5	GLY A 265 ASN A 267 ASN A 318 CYH A 315 LEU A 205	None MLD A1345 (-3.2A) MLD A1345 (-3.2A) None MLD A1345 ( 4.6A)	1.38A	6cenA-2cb3A: undetectable	6cenA-2cb3A: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2r3a	HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2 (Homo sapiens)	PF00856 (SET) PF05033 (Pre-SET)	6	ARG A 150 GLY A 149 HIS A 220 CYH A 287 CYH A 289 LEU A 298	None None SAM A 304 (-4.9A) ZN A 300 ( 2.3A) ZN A 300 ( 2.3A) SAM A 304 (-4.7A)	1.17A	6cenA-2r3aA: 20.3	6cenA-2r3aA: 29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2r3a	HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2 (Homo sapiens)	PF00856 (SET) PF05033 (Pre-SET)	10	ARG A 150 GLY A 151 TRP A 152 TYR A 193 ASN A 219 HIS A 220 TYR A 261 CYH A 287 CYH A 289 LEU A 298	None SAM A 304 (-3.5A) None SAM A 304 (-4.2A) SAM A 304 (-3.3A) SAM A 304 (-4.9A) SAM A 304 (-4.9A) ZN A 300 ( 2.3A) ZN A 300 ( 2.3A) SAM A 304 (-4.7A)	0.60A	6cenA-2r3aA: 20.3	6cenA-2r3aA: 29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2w5z	HISTONE-LYSINE N-METHYLTRANSFERASE HRX (Homo sapiens)	PF00856 (SET)	7	GLY A3840 ASN A3906 HIS A3907 TYR A3944 CYH A3957 CYH A3959 LEU A3968	SAH A4971 ( 3.7A) SAH A4971 (-3.1A) SAH A4971 (-4.7A) SAH A4971 (-4.9A) ZN A4970 ( 2.3A) ZN A4970 (-2.3A) SAH A4971 ( 4.9A)	0.53A	6cenA-2w5zA: 14.5	6cenA-2w5zA: 26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2w5z	HISTONE-LYSINE N-METHYLTRANSFERASE HRX (Homo sapiens)	PF00856 (SET)	5	GLY A3840 TYR A3883 ASN A3906 HIS A3907 CYH A3959	SAH A4971 ( 3.7A) None SAH A4971 (-3.1A) SAH A4971 (-4.7A) ZN A4970 (-2.3A)	0.69A	6cenA-2w5zA: 14.5	6cenA-2w5zA: 26.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3bo5	HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR (Homo sapiens)	PF00856 (SET) PF05033 (Pre-SET)	9	GLY A 136 TRP A 137 TYR A 178 ASN A 209 HIS A 210 TYR A 248 CYH A 273 CYH A 275 LEU A 284	SAH A 305 (-3.8A) None SAH A 305 (-4.0A) SAH A 305 (-3.4A) None SAH A 305 (-4.9A) ZN A 304 ( 2.3A) ZN A 304 ( 2.3A) SAH A 305 (-4.5A)	0.32A	6cenA-3bo5A: 20.8	6cenA-3bo5A: 31.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3bo5	HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR (Homo sapiens)	PF00856 (SET) PF05033 (Pre-SET)	5	GLY A 138 TYR A 178 HIS A 210 TYR A 248 CYH A 275	None SAH A 305 (-4.0A) None SAH A 305 (-4.9A) ZN A 304 ( 2.3A)	1.25A	6cenA-3bo5A: 20.8	6cenA-3bo5A: 31.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3n71	HISTONE LYSINE METHYLTRANSFERASE SMYD1 (Mus musculus)	PF00856 (SET) PF01753 (zf-MYND)	5	GLY A 18 ASN A 205 HIS A 206 TYR A 252 CYH A 274	SFG A 491 ( 4.2A) SFG A 491 (-3.3A) None SFG A 491 (-4.8A) ZN A 497 (-2.2A)	0.53A	6cenA-3n71A: 5.6	6cenA-3n71A: 15.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ooi	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC (Homo sapiens)	PF00856 (SET)	10	ARG A 101 GLY A 102 TRP A 103 ASN A 144 TYR A 146 ASN A 169 HIS A 170 CYH A 219 CYH A 221 LEU A 230	SO4 A 235 ( 4.0A) SAM A 237 ( 3.7A) None SAM A 237 (-3.9A) SAM A 237 (-4.1A) SAM A 237 (-3.3A) SAM A 237 (-4.7A) ZN A 232 ( 2.3A) ZN A 232 (-2.3A) SAM A 237 (-4.8A)	0.67A	6cenA-3ooiA: 32.8	6cenA-3ooiA: 76.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ooi	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC (Homo sapiens)	PF00856 (SET)	10	ARG A 101 GLY A 102 TRP A 103 ASN A 144 TYR A 146 ASN A 169 HIS A 170 TYR A 207 CYH A 219 CYH A 221	SO4 A 235 ( 4.0A) SAM A 237 ( 3.7A) None SAM A 237 (-3.9A) SAM A 237 (-4.1A) SAM A 237 (-3.3A) SAM A 237 (-4.7A) None ZN A 232 ( 2.3A) ZN A 232 (-2.3A)	0.34A	6cenA-3ooiA: 32.8	6cenA-3ooiA: 76.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ooi	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC (Homo sapiens)	PF00856 (SET)	7	GLY A 102 TRP A 103 ASN A 144 TYR A 146 ASN A 169 CYH A 171 LEU A 230	SAM A 237 ( 3.7A) None SAM A 237 (-3.9A) SAM A 237 (-4.1A) SAM A 237 (-3.3A) None SAM A 237 (-4.8A)	1.24A	6cenA-3ooiA: 32.8	6cenA-3ooiA: 76.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ooi	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC (Homo sapiens)	PF00856 (SET)	6	GLY A 102 TRP A 103 ASN A 169 HIS A 170 TYR A 207 CYH A 221	SAM A 237 ( 3.7A) None SAM A 237 (-3.3A) SAM A 237 (-4.7A) None ZN A 232 (-2.3A)	1.14A	6cenA-3ooiA: 32.8	6cenA-3ooiA: 76.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ope	PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L (Homo sapiens)	PF00856 (SET)	5	GLY A2151 TRP A2152 HIS A2218 TYR A2255 CYH A2268	SAM A 7 (-3.4A) None None None ZN A 1 ( 2.5A)	1.42A	6cenA-3opeA: 25.8	6cenA-3opeA: 40.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ope	PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L (Homo sapiens)	PF00856 (SET)	8	GLY A2151 TRP A2152 TYR A2194 ASN A2217 HIS A2218 TYR A2255 CYH A2268 CYH A2270	SAM A 7 (-3.4A) None SAM A 7 (-3.4A) SAM A 7 (-3.9A) None None ZN A 1 ( 2.5A) ZN A 1 (-2.7A)	0.49A	6cenA-3opeA: 25.8	6cenA-3opeA: 40.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ope	PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L (Homo sapiens)	PF00856 (SET)	5	GLY A2153 TYR A2194 HIS A2218 TYR A2255 CYH A2270	None SAM A 7 (-3.4A) None None ZN A 1 (-2.7A)	1.48A	6cenA-3opeA: 25.8	6cenA-3opeA: 40.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ope	PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L (Homo sapiens)	PF00856 (SET)	5	TRP A2152 ASN A2217 HIS A2218 TYR A2255 CYH A2270	None SAM A 7 (-3.9A) None None ZN A 1 (-2.7A)	1.06A	6cenA-3opeA: 25.8	6cenA-3opeA: 40.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3rc0	N-LYSINE METHYLTRANSFERASE SETD6 (Homo sapiens)	PF00856 (SET) PF09273 (Rubis-subs-bind)	5	GLY A 74 TYR A 223 ASN A 251 HIS A 252 TYR A 285	SAM A 484 (-3.4A) SAM A 484 (-3.6A) SAM A 484 (-3.1A) None SAM A 484 (-4.8A)	0.87A	6cenA-3rc0A: 5.8	6cenA-3rc0A: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4au7	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2 (Mus musculus)	PF00856 (SET)	5	ASN A 182 HIS A 183 TYR A 217 CYH A 229 CYH A 231	SAH A1247 (-3.1A) SAH A1247 (-4.6A) None ZN A1248 ( 2.3A) ZN A1248 ( 2.2A)	0.46A	6cenA-4au7A: 8.0	6cenA-4au7A: 24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4c1q	HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9 (Mus musculus)	PF00856 (SET)	5	GLY A 257 TYR A 291 ASN A 320 TYR A 357 LEU A 365	SAH A 394 ( 3.7A) SAH A 394 (-3.9A) SAH A 394 (-3.4A) None SAH A 394 ( 4.3A)	0.23A	6cenA-4c1qA: 9.2	6cenA-4c1qA: 20.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4fmu	HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 (Homo sapiens)	PF00856 (SET)	5	GLY A1561 TRP A1562 ASN A1628 HIS A1629 CYH A1680	0UM A1804 (-3.5A) None 0UM A1804 (-3.3A) None ZN A1803 (-2.2A)	1.31A	6cenA-4fmuA: 26.4	6cenA-4fmuA: 39.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4fmu	HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 (Homo sapiens)	PF00856 (SET)	8	GLY A1561 TRP A1562 TYR A1605 ASN A1628 HIS A1629 CYH A1678 CYH A1680 LEU A1689	0UM A1804 (-3.5A) None 0UM A1804 (-4.2A) 0UM A1804 (-3.3A) None ZN A1803 ( 2.2A) ZN A1803 (-2.2A) 0UM A1804 (-4.8A)	0.49A	6cenA-4fmuA: 26.4	6cenA-4fmuA: 39.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4mi5	HISTONE-LYSINE N-METHYLTRANSFERASE EZH2 (Homo sapiens)	PF00856 (SET)	5	GLY A 628 TRP A 629 ASN A 693 HIS A 694 TYR A 731	None	0.70A	6cenA-4mi5A: 15.6	6cenA-4mi5A: 30.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4qeo	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH4 (Arabidopsis thaliana)	PF00856 (SET) PF02182 (SAD_SRA) PF05033 (Pre-SET)	9	GLY A 457 TRP A 458 TYR A 493 ASN A 551 HIS A 552 TYR A 593 CYH A 612 CYH A 614 LEU A 623	SAH A 801 (-3.6A) SAH A 801 (-4.9A) SAH A 801 (-4.0A) SAH A 801 (-3.2A) None None ZN A 805 ( 2.4A) ZN A 805 ( 2.4A) None	0.61A	6cenA-4qeoA: 18.5	6cenA-4qeoA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4qeo	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH4 (Arabidopsis thaliana)	PF00856 (SET) PF02182 (SAD_SRA) PF05033 (Pre-SET)	6	GLY A 457 TRP A 458 TYR A 493 HIS A 552 TYR A 593 CYH A 614	SAH A 801 (-3.6A) SAH A 801 (-4.9A) SAH A 801 (-4.0A) None None ZN A 805 ( 2.4A)	1.45A	6cenA-4qeoA: 18.5	6cenA-4qeoA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4w2r	ENHANCER OF ZESTE 2 POLYCOMB REPRESSIVE COMPLEX 2 SUBUNIT (Anolis carolinensis)	no annotation	5	GLY A 520 TRP A 521 ASN A 585 HIS A 586 TYR A 623	CJD A 708 (-3.6A) None CJD A 708 (-3.5A) None None	0.56A	6cenA-4w2rA: 22.1	6cenA-4w2rA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4z4p	HISTONE-LYSINE N-METHYLTRANSFERASE 2D (Homo sapiens)	PF00856 (SET)	7	GLY A5408 TYR A5451 ASN A5474 HIS A5475 TYR A5512 CYH A5525 CYH A5527	SAH A5602 (-3.6A) SAH A5602 (-4.5A) SAH A5602 (-3.1A) None None ZN A5601 ( 2.2A) ZN A5601 ( 2.2A)	0.49A	6cenA-4z4pA: 16.7	6cenA-4z4pA: 24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	PF00856 (SET)	5	ASN B 272 HIS B 273 TYR B 307 CYH B 319 CYH B 321	SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) ZN B 401 ( 2.3A) ZN B 401 ( 2.2A)	0.53A	6cenA-5cprB: 7.4	6cenA-5cprB: 23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5f59	HISTONE-LYSINE N-METHYLTRANSFERASE 2C (Homo sapiens)	PF00856 (SET)	7	GLY A4782 TYR A4825 ASN A4848 HIS A4849 TYR A4886 CYH A4899 CYH A4901	SAH A5002 (-3.5A) SAH A5002 (-4.5A) SAH A5002 (-2.7A) SAH A5002 (-4.6A) None ZN A5001 ( 2.0A) ZN A5001 (-2.3A)	0.67A	6cenA-5f59A: 16.5	6cenA-5f59A: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5f6l	HISTONE-LYSINE N-METHYLTRANSFERASE 2A (Homo sapiens)	PF00856 (SET)	8	GLY A3840 TYR A3883 ASN A3906 HIS A3907 TYR A3944 CYH A3957 CYH A3959 LEU A3968	SAH A4001 (-3.4A) None SAH A4001 (-3.0A) SAH A4001 (-4.9A) SAH A4001 (-4.9A) ZN A4002 ( 2.3A) ZN A4002 (-2.3A) None	0.72A	6cenA-5f6lA: 16.1	6cenA-5f6lA: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5f7s	GLYCOSIDE HYDROLASE FAMILY 31 (Trueperella pyogenes)	PF01055 (Glyco_hydro_31) PF13802 (Gal_mutarotas_2)	5	ARG A 452 GLY A 337 TYR A 346 TYR A 454 LEU A 455	None	1.45A	6cenA-5f7sA: undetectable	6cenA-5f7sA: 14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5kca	CEREBELLIN-1,CEREBEL LIN-1,CEREBELLIN-1,G LUTAMATE RECEPTOR IONOTROPIC, DELTA-2 (Homo sapiens)	PF00386 (C1q) PF01094 (ANF_receptor)	5	ARG A 786 GLY A 787 ASN A 540 TYR A 814 LEU A 818	None	1.39A	6cenA-5kcaA: undetectable	6cenA-5kcaA: 12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5kjm	N-LYSINE METHYLTRANSFERASE SMYD2 (Homo sapiens)	PF00856 (SET) PF01753 (zf-MYND)	5	GLY A 18 ASN A 206 HIS A 207 TYR A 240 CYH A 262	SAM A 501 ( 4.1A) SAM A 501 (-3.2A) None 6TM A 502 ( 3.6A) ZN A 505 (-2.3A)	0.56A	6cenA-5kjmA: 6.0	6cenA-5kjmA: 19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ls6	HISTONE-LYSINE N-METHYLTRANSFERASE EZH2,HISTONE-LYSINE N-METHYLTRANSFERASE EZH2,HISTONE-LYSINE N-METHYLTRANSFERASE EZH2 (Homo sapiens)	PF00856 (SET) PF11616 (EZH2_WD-Binding)	5	GLY A 623 TRP A 624 ASN A 688 HIS A 689 TYR A 726	74D A 809 ( 3.9A) None 74D A 809 (-3.0A) None None	0.81A	6cenA-5ls6A: 19.7	6cenA-5ls6A: 15.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5lsu	HISTONE-LYSINE N-METHYLTRANSFERASE NSD2 (Homo sapiens)	PF00856 (SET)	10	ARG A1073 GLY A1074 TRP A1075 TYR A1118 ASN A1141 HIS A1142 TYR A1179 CYH A1191 CYH A1193 LEU A1202	None SAM A1304 ( 3.2A) None SAM A1304 (-3.8A) SAM A1304 (-2.9A) SAM A1304 (-4.6A) SAM A1304 (-4.1A) ZN A1301 ( 2.3A) ZN A1301 (-2.3A) SAM A1304 ( 4.7A)	0.46A	6cenA-5lsuA: 32.5	6cenA-5lsuA: 77.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5teg	N-LYSINE METHYLTRANSFERASE KMT5A (Homo sapiens)	PF00856 (SET)	5	GLY A 227 TYR A 271 ASN A 298 HIS A 299 TYR A 336	SAM A 401 ( 4.0A) SAM A 401 (-4.1A) SAM A 401 (-3.2A) None SAM A 401 (-4.8A)	0.24A	6cenA-5tegA: 15.2	6cenA-5tegA: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5tuy	HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2 (Homo sapiens)	PF00856 (SET) PF05033 (Pre-SET)	8	GLY A1049 TRP A1050 TYR A1085 ASN A1112 HIS A1113 TYR A1154 CYH A1168 CYH A1170	SAM A1505 ( 3.9A) None SAM A1505 (-4.0A) SAM A1505 (-3.4A) SAM A1505 (-4.7A) SAM A1505 (-4.9A) ZN A1504 (-2.2A) ZN A1504 (-2.2A)	0.42A	6cenA-5tuyA: 19.6	6cenA-5tuyA: 29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5udh	E3 UBIQUITIN-PROTEIN LIGASE ARIH1 (Homo sapiens)	PF01485 (IBR)	5	ASN A 310 HIS A 312 TYR A 474 CYH A 304 LEU A 320	None ZN A 604 (-3.2A) None ZN A 604 (-2.3A) None	1.04A	6cenA-5udhA: undetectable	6cenA-5udhA: 18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5vsd	HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1 (Homo sapiens)	PF00856 (SET) PF05033 (Pre-SET)	5	GLY A1137 TRP A1138 HIS A1201 TYR A1242 CYH A1256	SAM A3001 (-3.6A) None SAM A3001 (-4.6A) SAM A3001 (-4.8A) ZN A3005 ( 2.4A)	1.50A	6cenA-5vsdA: 20.1	6cenA-5vsdA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5vsd	HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1 (Homo sapiens)	PF00856 (SET) PF05033 (Pre-SET)	8	GLY A1137 TRP A1138 TYR A1173 ASN A1200 HIS A1201 TYR A1242 CYH A1256 CYH A1258	SAM A3001 (-3.6A) None SAM A3001 (-4.0A) SAM A3001 (-3.4A) SAM A3001 (-4.6A) SAM A3001 (-4.8A) ZN A3005 ( 2.4A) ZN A3005 (-2.3A)	0.51A	6cenA-5vsdA: 20.1	6cenA-5vsdA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5vsd	HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1 (Homo sapiens)	PF00856 (SET) PF05033 (Pre-SET)	5	GLY A1139 TYR A1173 HIS A1201 TYR A1242 CYH A1258	None SAM A3001 (-4.0A) SAM A3001 (-4.6A) SAM A3001 (-4.8A) ZN A3005 (-2.3A)	1.46A	6cenA-5vsdA: 20.1	6cenA-5vsdA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5wg6	HISTONE-LYSINE N-METHYLTRANSFERASE EZH2,POLYCOMB PROTEIN SUZ12 (E.C.2.1.1.43) CHIMERA (Homo sapiens)	no annotation	5	GLY A 623 TRP A 624 ASN A 688 HIS A 689 TYR A 726	A9G A9009 ( 4.2A) None A9G A9009 (-3.1A) None None	0.70A	6cenA-5wg6A: 19.6	6cenA-5wg6A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6cen	HISTONE-LYSINE N-METHYLTRANSFERASE NSD3 (Homo sapiens)	no annotation	11	ARG A1155 GLY A1156 TRP A1157 ASN A1198 TYR A1200 ASN A1223 HIS A1224 TYR A1261 CYH A1273 CYH A1275 LEU A1284	None SAM A1301 (-3.6A) None SAM A1301 (-3.8A) SAM A1301 (-3.9A) SAM A1301 (-3.2A) None SAM A1301 (-4.9A) ZN A1304 ( 2.3A) ZN A1304 (-2.3A) SAM A1301 (-4.6A)	0.03A	6cenA-6cenA: 38.5	6cenA-6cenA: undetectable

[["6CEN_A_SAMA1301_0","1id0","Escherichia coli","PHOQ HISTIDINE KINASE","PF02518(HATPase_c)",5,"GLY A 443;ASN A 389;TYR A 393;TYR A 355;LEU A 351"," MG A 700 ( 4.4A);ANP A 487 (-3.0A);ANP A 487 (-4.0A);None;None","1.19A","6cenA-1id0A:0.0","6cenA-1id0A:21.21"],["6CEN_A_SAMA1301_0","1mvh","Schizosaccharomyces pombe","CRYPTIC LOCI REGULATOR 4","PF00856(SET);PF05033(Pre-SET)",5,"GLY A 339;TRP A 340;TYR A 381;ASN A 409;HIS A 410","None","0.40A","6cenA-1mvhA:17.6","6cenA-1mvhA:27.42"],["6CEN_A_SAMA1301_0","1peg","Neurospora crassa","HISTONE H3 METHYLTRANSFERASE DIM-5","PF00856(SET);PF05033(Pre-SET)",10,"ARG A 159;GLY A 160;TRP A 161;TYR A 204;ASN A 241;HIS A 242;TYR A 283;CYH A 306;CYH A 308;LEU A 317","None;SAH A 319 ( 4.6A);SAH A 319 (-4.8A);SAH A 319 (-4.0A);SAH A 319 (-3.6A);SAH A 319 (-4.3A);SAH A 319 (-4.7A); ZN A   4 ( 2.3A); ZN A   4 (-2.2A);SAH A 319 (-3.9A)","0.84A","6cenA-1pegA:19.9","6cenA-1pegA:29.17"],["6CEN_A_SAMA1301_0","1peg","Neurospora crassa","HISTONE H3 METHYLTRANSFERASE DIM-5","PF00856(SET);PF05033(Pre-SET)",6,"ARG A 159;TRP A 161;ASN A 241;HIS A 242;TYR A 283;CYH A 308","None;SAH A 319 (-4.8A);SAH A 319 (-3.6A);SAH A 319 (-4.3A);SAH A 319 (-4.7A); ZN A   4 (-2.2A)","1.49A","6cenA-1pegA:19.9","6cenA-1pegA:29.17"],["6CEN_A_SAMA1301_0","1r76","Niveispirillum irakense","PECTATE LYASE","PF09492(Pec_lyase)",5,"GLY A 217;TRP A 218;TYR A  55;ASN A 215;LEU A 299","None;None;None; HG A4000 (-3.4A);None","1.47A","6cenA-1r76A:undetectable","6cenA-1r76A:16.67"],["6CEN_A_SAMA1301_0","1we5","Escherichia coli","PUTATIVE FAMILY 31 GLUCOSIDASE YICI","PF01055(Glyco_hydro_31);PF13802(Gal_mutarotas_2)",5,"GLY A 159;ASN A 175;ASN A 203;TYR A 163;CYH A 601","None","1.43A","6cenA-1we5A:undetectable","6cenA-1we5A:13.56"],["6CEN_A_SAMA1301_0","2cb3","Drosophila melanogaster","PEPTIDOGLYCAN-RECOGNITION PROTEIN-LE","PF01510(Amidase_2)",5,"GLY A 265;ASN A 267;ASN A 318;CYH A 315;LEU A 205","None;MLD A1345 (-3.2A);MLD A1345 (-3.2A);None;MLD A1345 ( 4.6A)","1.38A","6cenA-2cb3A:undetectable","6cenA-2cb3A:21.22"],["6CEN_A_SAMA1301_0","2r3a","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2","PF00856(SET);PF05033(Pre-SET)",6,"ARG A 150;GLY A 149;HIS A 220;CYH A 287;CYH A 289;LEU A 298","None;None;SAM A 304 (-4.9A); ZN A 300 ( 2.3A); ZN A 300 ( 2.3A);SAM A 304 (-4.7A)","1.17A","6cenA-2r3aA:20.3","6cenA-2r3aA:29.04"],["6CEN_A_SAMA1301_0","2r3a","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H2","PF00856(SET);PF05033(Pre-SET)",10,"ARG A 150;GLY A 151;TRP A 152;TYR A 193;ASN A 219;HIS A 220;TYR A 261;CYH A 287;CYH A 289;LEU A 298","None;SAM A 304 (-3.5A);None;SAM A 304 (-4.2A);SAM A 304 (-3.3A);SAM A 304 (-4.9A);SAM A 304 (-4.9A); ZN A 300 ( 2.3A); ZN A 300 ( 2.3A);SAM A 304 (-4.7A)","0.60A","6cenA-2r3aA:20.3","6cenA-2r3aA:29.04"],["6CEN_A_SAMA1301_0","2w5z","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE HRX","PF00856(SET)",7,"GLY A3840;ASN A3906;HIS A3907;TYR A3944;CYH A3957;CYH A3959;LEU A3968","SAH A4971 ( 3.7A);SAH A4971 (-3.1A);SAH A4971 (-4.7A);SAH A4971 (-4.9A); ZN A4970 ( 2.3A); ZN A4970 (-2.3A);SAH A4971 ( 4.9A)","0.53A","6cenA-2w5zA:14.5","6cenA-2w5zA:26.72"],["6CEN_A_SAMA1301_0","2w5z","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE HRX","PF00856(SET)",5,"GLY A3840;TYR A3883;ASN A3906;HIS A3907;CYH A3959","SAH A4971 ( 3.7A);None;SAH A4971 (-3.1A);SAH A4971 (-4.7A); ZN A4970 (-2.3A)","0.69A","6cenA-2w5zA:14.5","6cenA-2w5zA:26.72"],["6CEN_A_SAMA1301_0","3bo5","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR","PF00856(SET);PF05033(Pre-SET)",9,"GLY A 136;TRP A 137;TYR A 178;ASN A 209;HIS A 210;TYR A 248;CYH A 273;CYH A 275;LEU A 284","SAH A 305 (-3.8A);None;SAH A 305 (-4.0A);SAH A 305 (-3.4A);None;SAH A 305 (-4.9A); ZN A 304 ( 2.3A); ZN A 304 ( 2.3A);SAH A 305 (-4.5A)","0.32A","6cenA-3bo5A:20.8","6cenA-3bo5A:31.16"],["6CEN_A_SAMA1301_0","3bo5","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR","PF00856(SET);PF05033(Pre-SET)",5,"GLY A 138;TYR A 178;HIS A 210;TYR A 248;CYH A 275","None;SAH A 305 (-4.0A);None;SAH A 305 (-4.9A); ZN A 304 ( 2.3A)","1.25A","6cenA-3bo5A:20.8","6cenA-3bo5A:31.16"],["6CEN_A_SAMA1301_0","3n71","Mus musculus","HISTONE LYSINE METHYLTRANSFERASE SMYD1","PF00856(SET);PF01753(zf-MYND)",5,"GLY A  18;ASN A 205;HIS A 206;TYR A 252;CYH A 274","SFG A 491 ( 4.2A);SFG A 491 (-3.3A);None;SFG A 491 (-4.8A); ZN A 497 (-2.2A)","0.53A","6cenA-3n71A:5.6","6cenA-3n71A:15.35"],["6CEN_A_SAMA1301_0","3ooi","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC","PF00856(SET)",10,"ARG A 101;GLY A 102;TRP A 103;ASN A 144;TYR A 146;ASN A 169;HIS A 170;CYH A 219;CYH A 221;LEU A 230","SO4 A 235 ( 4.0A);SAM A 237 ( 3.7A);None;SAM A 237 (-3.9A);SAM A 237 (-4.1A);SAM A 237 (-3.3A);SAM A 237 (-4.7A); ZN A 232 ( 2.3A); ZN A 232 (-2.3A);SAM A 237 (-4.8A)","0.67A","6cenA-3ooiA:32.8","6cenA-3ooiA:76.62"],["6CEN_A_SAMA1301_0","3ooi","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC","PF00856(SET)",10,"ARG A 101;GLY A 102;TRP A 103;ASN A 144;TYR A 146;ASN A 169;HIS A 170;TYR A 207;CYH A 219;CYH A 221","SO4 A 235 ( 4.0A);SAM A 237 ( 3.7A);None;SAM A 237 (-3.9A);SAM A 237 (-4.1A);SAM A 237 (-3.3A);SAM A 237 (-4.7A);None; ZN A 232 ( 2.3A); ZN A 232 (-2.3A)","0.34A","6cenA-3ooiA:32.8","6cenA-3ooiA:76.62"],["6CEN_A_SAMA1301_0","3ooi","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC","PF00856(SET)",7,"GLY A 102;TRP A 103;ASN A 144;TYR A 146;ASN A 169;CYH A 171;LEU A 230","SAM A 237 ( 3.7A);None;SAM A 237 (-3.9A);SAM A 237 (-4.1A);SAM A 237 (-3.3A);None;SAM A 237 (-4.8A)","1.24A","6cenA-3ooiA:32.8","6cenA-3ooiA:76.62"],["6CEN_A_SAMA1301_0","3ooi","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC","PF00856(SET)",6,"GLY A 102;TRP A 103;ASN A 169;HIS A 170;TYR A 207;CYH A 221","SAM A 237 ( 3.7A);None;SAM A 237 (-3.3A);SAM A 237 (-4.7A);None; ZN A 232 (-2.3A)","1.14A","6cenA-3ooiA:32.8","6cenA-3ooiA:76.62"],["6CEN_A_SAMA1301_0","3ope","Homo sapiens","PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L","PF00856(SET)",5,"GLY A2151;TRP A2152;HIS A2218;TYR A2255;CYH A2268","SAM A   7 (-3.4A);None;None;None; ZN A   1 ( 2.5A)","1.42A","6cenA-3opeA:25.8","6cenA-3opeA:40.60"],["6CEN_A_SAMA1301_0","3ope","Homo sapiens","PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L","PF00856(SET)",8,"GLY A2151;TRP A2152;TYR A2194;ASN A2217;HIS A2218;TYR A2255;CYH A2268;CYH A2270","SAM A   7 (-3.4A);None;SAM A   7 (-3.4A);SAM A   7 (-3.9A);None;None; ZN A   1 ( 2.5A); ZN A   1 (-2.7A)","0.49A","6cenA-3opeA:25.8","6cenA-3opeA:40.60"],["6CEN_A_SAMA1301_0","3ope","Homo sapiens","PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L","PF00856(SET)",5,"GLY A2153;TYR A2194;HIS A2218;TYR A2255;CYH A2270","None;SAM A   7 (-3.4A);None;None; ZN A   1 (-2.7A)","1.48A","6cenA-3opeA:25.8","6cenA-3opeA:40.60"],["6CEN_A_SAMA1301_0","3ope","Homo sapiens","PROBABLE HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L","PF00856(SET)",5,"TRP A2152;ASN A2217;HIS A2218;TYR A2255;CYH A2270","None;SAM A   7 (-3.9A);None;None; ZN A   1 (-2.7A)","1.06A","6cenA-3opeA:25.8","6cenA-3opeA:40.60"],["6CEN_A_SAMA1301_0","3rc0","Homo sapiens","N-LYSINE METHYLTRANSFERASE SETD6","PF00856(SET);PF09273(Rubis-subs-bind)",5,"GLY A  74;TYR A 223;ASN A 251;HIS A 252;TYR A 285","SAM A 484 (-3.4A);SAM A 484 (-3.6A);SAM A 484 (-3.1A);None;SAM A 484 (-4.8A)","0.87A","6cenA-3rc0A:5.8","6cenA-3rc0A:17.45"],["6CEN_A_SAMA1301_0","4au7","Mus musculus","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2","PF00856(SET)",5,"ASN A 182;HIS A 183;TYR A 217;CYH A 229;CYH A 231","SAH A1247 (-3.1A);SAH A1247 (-4.6A);None; ZN A1248 ( 2.3A); ZN A1248 ( 2.2A)","0.46A","6cenA-4au7A:8.0","6cenA-4au7A:24.23"],["6CEN_A_SAMA1301_0","4c1q","Mus musculus","HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9","PF00856(SET)",5,"GLY A 257;TYR A 291;ASN A 320;TYR A 357;LEU A 365","SAH A 394 ( 3.7A);SAH A 394 (-3.9A);SAH A 394 (-3.4A);None;SAH A 394 ( 4.3A)","0.23A","6cenA-4c1qA:9.2","6cenA-4c1qA:20.75"],["6CEN_A_SAMA1301_0","4fmu","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE SETD2","PF00856(SET)",5,"GLY A1561;TRP A1562;ASN A1628;HIS A1629;CYH A1680","0UM A1804 (-3.5A);None;0UM A1804 (-3.3A);None; ZN A1803 (-2.2A)","1.31A","6cenA-4fmuA:26.4","6cenA-4fmuA:39.02"],["6CEN_A_SAMA1301_0","4fmu","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE SETD2","PF00856(SET)",8,"GLY A1561;TRP A1562;TYR A1605;ASN A1628;HIS A1629;CYH A1678;CYH A1680;LEU A1689","0UM A1804 (-3.5A);None;0UM A1804 (-4.2A);0UM A1804 (-3.3A);None; ZN A1803 ( 2.2A); ZN A1803 (-2.2A);0UM A1804 (-4.8A)","0.49A","6cenA-4fmuA:26.4","6cenA-4fmuA:39.02"],["6CEN_A_SAMA1301_0","4mi5","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE EZH2","PF00856(SET)",5,"GLY A 628;TRP A 629;ASN A 693;HIS A 694;TYR A 731","None","0.70A","6cenA-4mi5A:15.6","6cenA-4mi5A:30.59"],["6CEN_A_SAMA1301_0","4qeo","Arabidopsis thaliana","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH4","PF00856(SET);PF02182(SAD_SRA);PF05033(Pre-SET)",9,"GLY A 457;TRP A 458;TYR A 493;ASN A 551;HIS A 552;TYR A 593;CYH A 612;CYH A 614;LEU A 623","SAH A 801 (-3.6A);SAH A 801 (-4.9A);SAH A 801 (-4.0A);SAH A 801 (-3.2A);None;None; ZN A 805 ( 2.4A); ZN A 805 ( 2.4A);None","0.61A","6cenA-4qeoA:18.5","6cenA-4qeoA:19.37"],["6CEN_A_SAMA1301_0","4qeo","Arabidopsis thaliana","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH4","PF00856(SET);PF02182(SAD_SRA);PF05033(Pre-SET)",6,"GLY A 457;TRP A 458;TYR A 493;HIS A 552;TYR A 593;CYH A 614","SAH A 801 (-3.6A);SAH A 801 (-4.9A);SAH A 801 (-4.0A);None;None; ZN A 805 ( 2.4A)","1.45A","6cenA-4qeoA:18.5","6cenA-4qeoA:19.37"],["6CEN_A_SAMA1301_0","4w2r","Anolis carolinensis","ENHANCER OF ZESTE 2 POLYCOMB REPRESSIVE COMPLEX 2 SUBUNIT","no annotation",5,"GLY A 520;TRP A 521;ASN A 585;HIS A 586;TYR A 623","CJD A 708 (-3.6A);None;CJD A 708 (-3.5A);None;None","0.56A","6cenA-4w2rA:22.1","6cenA-4w2rA:undetectable"],["6CEN_A_SAMA1301_0","4z4p","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE 2D","PF00856(SET)",7,"GLY A5408;TYR A5451;ASN A5474;HIS A5475;TYR A5512;CYH A5525;CYH A5527","SAH A5602 (-3.6A);SAH A5602 (-4.5A);SAH A5602 (-3.1A);None;None; ZN A5601 ( 2.2A); ZN A5601 ( 2.2A)","0.49A","6cenA-4z4pA:16.7","6cenA-4z4pA:24.35"],["6CEN_A_SAMA1301_0","5cpr","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","PF00856(SET)",5,"ASN B 272;HIS B 273;TYR B 307;CYH B 319;CYH B 321","SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A); ZN B 401 ( 2.3A); ZN B 401 ( 2.2A)","0.53A","6cenA-5cprB:7.4","6cenA-5cprB:23.76"],["6CEN_A_SAMA1301_0","5f59","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE 2C","PF00856(SET)",7,"GLY A4782;TYR A4825;ASN A4848;HIS A4849;TYR A4886;CYH A4899;CYH A4901","SAH A5002 (-3.5A);SAH A5002 (-4.5A);SAH A5002 (-2.7A);SAH A5002 (-4.6A);None; ZN A5001 ( 2.0A); ZN A5001 (-2.3A)","0.67A","6cenA-5f59A:16.5","6cenA-5f59A:22.81"],["6CEN_A_SAMA1301_0","5f6l","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE 2A","PF00856(SET)",8,"GLY A3840;TYR A3883;ASN A3906;HIS A3907;TYR A3944;CYH A3957;CYH A3959;LEU A3968","SAH A4001 (-3.4A);None;SAH A4001 (-3.0A);SAH A4001 (-4.9A);SAH A4001 (-4.9A); ZN A4002 ( 2.3A); ZN A4002 (-2.3A);None","0.72A","6cenA-5f6lA:16.1","6cenA-5f6lA:25.00"],["6CEN_A_SAMA1301_0","5f7s","Trueperella pyogenes","GLYCOSIDE HYDROLASE FAMILY 31","PF01055(Glyco_hydro_31);PF13802(Gal_mutarotas_2)",5,"ARG A 452;GLY A 337;TYR A 346;TYR A 454;LEU A 455","None","1.45A","6cenA-5f7sA:undetectable","6cenA-5f7sA:14.15"],["6CEN_A_SAMA1301_0","5kca","Homo sapiens","CEREBELLIN-1,CEREBELLIN-1,CEREBELLIN-1,GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2","PF00386(C1q);PF01094(ANF_receptor)",5,"ARG A 786;GLY A 787;ASN A 540;TYR A 814;LEU A 818","None","1.39A","6cenA-5kcaA:undetectable","6cenA-5kcaA:12.99"],["6CEN_A_SAMA1301_0","5kjm","Homo sapiens","N-LYSINE METHYLTRANSFERASE SMYD2","PF00856(SET);PF01753(zf-MYND)",5,"GLY A  18;ASN A 206;HIS A 207;TYR A 240;CYH A 262","SAM A 501 ( 4.1A);SAM A 501 (-3.2A);None;6TM A 502 ( 3.6A); ZN A 505 (-2.3A)","0.56A","6cenA-5kjmA:6.0","6cenA-5kjmA:19.39"],["6CEN_A_SAMA1301_0","5ls6","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE EZH2,HISTONE-LYSINE N-METHYLTRANSFERASE EZH2,HISTONE-LYSINE N-METHYLTRANSFERASE EZH2","PF00856(SET);PF11616(EZH2_WD-Binding)",5,"GLY A 623;TRP A 624;ASN A 688;HIS A 689;TYR A 726","74D A 809 ( 3.9A);None;74D A 809 (-3.0A);None;None","0.81A","6cenA-5ls6A:19.7","6cenA-5ls6A:15.68"],["6CEN_A_SAMA1301_0","5lsu","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE NSD2","PF00856(SET)",10,"ARG A1073;GLY A1074;TRP A1075;TYR A1118;ASN A1141;HIS A1142;TYR A1179;CYH A1191;CYH A1193;LEU A1202","None;SAM A1304 ( 3.2A);None;SAM A1304 (-3.8A);SAM A1304 (-2.9A);SAM A1304 (-4.6A);SAM A1304 (-4.1A); ZN A1301 ( 2.3A); ZN A1301 (-2.3A);SAM A1304 ( 4.7A)","0.46A","6cenA-5lsuA:32.5","6cenA-5lsuA:77.49"],["6CEN_A_SAMA1301_0","5teg","Homo sapiens","N-LYSINE METHYLTRANSFERASE KMT5A","PF00856(SET)",5,"GLY A 227;TYR A 271;ASN A 298;HIS A 299;TYR A 336","SAM A 401 ( 4.0A);SAM A 401 (-4.1A);SAM A 401 (-3.2A);None;SAM A 401 (-4.8A)","0.24A","6cenA-5tegA:15.2","6cenA-5tegA:23.08"],["6CEN_A_SAMA1301_0","5tuy","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE EHMT2","PF00856(SET);PF05033(Pre-SET)",8,"GLY A1049;TRP A1050;TYR A1085;ASN A1112;HIS A1113;TYR A1154;CYH A1168;CYH A1170","SAM A1505 ( 3.9A);None;SAM A1505 (-4.0A);SAM A1505 (-3.4A);SAM A1505 (-4.7A);SAM A1505 (-4.9A); ZN A1504 (-2.2A); ZN A1504 (-2.2A)","0.42A","6cenA-5tuyA:19.6","6cenA-5tuyA:29.75"],["6CEN_A_SAMA1301_0","5udh","Homo sapiens","E3 UBIQUITIN-PROTEIN LIGASE ARIH1","PF01485(IBR)",5,"ASN A 310;HIS A 312;TYR A 474;CYH A 304;LEU A 320","None; ZN A 604 (-3.2A);None; ZN A 604 (-2.3A);None","1.04A","6cenA-5udhA:undetectable","6cenA-5udhA:18.03"],["6CEN_A_SAMA1301_0","5vsd","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1","PF00856(SET);PF05033(Pre-SET)",5,"GLY A1137;TRP A1138;HIS A1201;TYR A1242;CYH A1256","SAM A3001 (-3.6A);None;SAM A3001 (-4.6A);SAM A3001 (-4.8A); ZN A3005 ( 2.4A)","1.50A","6cenA-5vsdA:20.1","6cenA-5vsdA:27.41"],["6CEN_A_SAMA1301_0","5vsd","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1","PF00856(SET);PF05033(Pre-SET)",8,"GLY A1137;TRP A1138;TYR A1173;ASN A1200;HIS A1201;TYR A1242;CYH A1256;CYH A1258","SAM A3001 (-3.6A);None;SAM A3001 (-4.0A);SAM A3001 (-3.4A);SAM A3001 (-4.6A);SAM A3001 (-4.8A); ZN A3005 ( 2.4A); ZN A3005 (-2.3A)","0.51A","6cenA-5vsdA:20.1","6cenA-5vsdA:27.41"],["6CEN_A_SAMA1301_0","5vsd","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1","PF00856(SET);PF05033(Pre-SET)",5,"GLY A1139;TYR A1173;HIS A1201;TYR A1242;CYH A1258","None;SAM A3001 (-4.0A);SAM A3001 (-4.6A);SAM A3001 (-4.8A); ZN A3005 (-2.3A)","1.46A","6cenA-5vsdA:20.1","6cenA-5vsdA:27.41"],["6CEN_A_SAMA1301_0","5wg6","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE EZH2,POLYCOMB PROTEIN SUZ12 (E.C.2.1.1.43) CHIMERA","no annotation",5,"GLY A 623;TRP A 624;ASN A 688;HIS A 689;TYR A 726","A9G A9009 ( 4.2A);None;A9G A9009 (-3.1A);None;None","0.70A","6cenA-5wg6A:19.6","6cenA-5wg6A:undetectable"],["6CEN_A_SAMA1301_0","6cen","Homo sapiens","HISTONE-LYSINE N-METHYLTRANSFERASE NSD3","no annotation",11,"ARG A1155;GLY A1156;TRP A1157;ASN A1198;TYR A1200;ASN A1223;HIS A1224;TYR A1261;CYH A1273;CYH A1275;LEU A1284","None;SAM A1301 (-3.6A);None;SAM A1301 (-3.8A);SAM A1301 (-3.9A);SAM A1301 (-3.2A);None;SAM A1301 (-4.9A); ZN A1304 ( 2.3A); ZN A1304 (-2.3A);SAM A1301 (-4.6A)","0.03A","6cenA-6cenA:38.5","6cenA-6cenA:undetectable"]]