SIMILAR PATTERNS OF AMINO ACIDS FOR 6C71_D_NCTD501

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)

Filter list by:

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	PF00128 (Alpha-amylase) PF09154 (DUF1939)	5	LEU A 537 TYR A 520 GLU A 511 THR A 472 ASN A 431	None	1.47A	6c71D-3bc9A: 0.0	6c71D-3bc9A: 9.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5ttk	AMINE OXIDASE (Pseudomonas putida)	PF01593 (Amino_oxidase)	6	LEU A 217 TYR A 218 GLU A 249 THR A 250 THR A 381 TRP A 427	None	1.44A	6c71D-5ttkA: 64.4	6c71D-5ttkA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5ttk	AMINE OXIDASE (Pseudomonas putida)	PF01593 (Amino_oxidase)	5	TYR A 218 THR A 250 THR A 381 TRP A 427 ASN A 462	None None None None FAD A 501 (-3.8A)	0.77A	6c71D-5ttkA: 64.4	6c71D-5ttkA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6f4f	GLUTATHIONE TRANSFERASE (Trametes versicolor)	no annotation	5	LEU A 9 TYR A 32 GLU A 26 THR A 219 THR A 11	None	0.97A	6c71D-6f4fA: 0.0	6c71D-6f4fA: 26.19