SIMILAR PATTERNS OF AMINO ACIDS FOR 6C2M_D_SUED1202_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bhg | BETA-GLUCURONIDASE (Homo sapiens) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 4 | VAL A 120LEU A 28VAL A 250SER A 249 | None | 0.97A | 6c2mD-1bhgA:0.0 | 6c2mD-1bhgA:8.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cf2 | PROTEIN(GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE) (Methanothermusfervidus) |
no annotation | 4 | VAL P 298HIS P 299ASP P 303SER P 119 | None | 0.95A | 6c2mD-1cf2P:undetectable | 6c2mD-1cf2P:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ck7 | PROTEIN (GELATINASEA) (Homo sapiens) |
PF00040(fn2)PF00045(Hemopexin)PF00413(Peptidase_M10)PF01471(PG_binding_1) | 4 | PHE A 207VAL A 400HIS A 403LEU A 212 | NoneNone ZN A 990 ( 3.4A)None | 0.96A | 6c2mD-1ck7A:0.3 | 6c2mD-1ck7A:7.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cs1 | PROTEIN(CYSTATHIONINEGAMMA-SYNTHASE) (Escherichiacoli) |
PF01053(Cys_Met_Meta_PP) | 4 | LEU A 185VAL A 171SER A 170ASP A 173 | NoneNoneNoneLLP A 198 ( 3.0A) | 0.91A | 6c2mD-1cs1A:0.0 | 6c2mD-1cs1A:10.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cs1 | PROTEIN(CYSTATHIONINEGAMMA-SYNTHASE) (Escherichiacoli) |
PF01053(Cys_Met_Meta_PP) | 4 | VAL A 219LEU A 61VAL A 56ASP A 55 | None | 0.98A | 6c2mD-1cs1A:0.0 | 6c2mD-1cs1A:10.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1cu1 | PROTEIN(PROTEASE/HELICASENS3) (Hepacivirus C) |
PF02907(Peptidase_S29)PF07652(Flavi_DEAD) | 6 | PHE A 43VAL A 55ASP A 81LEU A 135VAL A 158ASP A 168 | None | 0.38A | 6c2mD-1cu1A:34.4 | 6c2mD-1cu1A:47.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dl3 | PROTEIN(PHOSPHORIBOSYLANTRANILATE ISOMERASE) (Thermotogamaritima) |
PF00697(PRAI) | 4 | PHE A 121LEU A 154VAL A 177ASP A 178 | None | 0.84A | 6c2mD-1dl3A:0.0 | 6c2mD-1dl3A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e3j | NADP(H)-DEPENDENTKETOSE REDUCTASE (Bemisiaargentifolii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | HIS A 321LEU A 154VAL A 185SER A 184 | None | 0.97A | 6c2mD-1e3jA:0.0 | 6c2mD-1e3jA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8f | BENZYL ALCOHOLDEHYDROGENASE (Acinetobactercalcoaceticus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | ASP A 47LEU A 364VAL A 202SER A 205 | NoneNoneNAD A 375 (-3.6A)None | 0.94A | 6c2mD-1f8fA:0.0 | 6c2mD-1f8fA:12.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fbl | FIBROBLAST(INTERSTITIAL)COLLAGENASE (MMP-1) (Sus scrofa) |
PF00045(Hemopexin)PF00413(Peptidase_M10) | 4 | PHE A 197VAL A 215HIS A 218ASP A 209 | NoneHTA A 900 ( 4.0A) ZN A 998 ( 3.5A)None | 0.92A | 6c2mD-1fblA:0.0 | 6c2mD-1fblA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hqs | ISOCITRATEDEHYDROGENASE (Bacillussubtilis) |
PF00180(Iso_dh) | 4 | VAL A 107VAL A 192SER A 193ASP A 149 | None | 0.97A | 6c2mD-1hqsA:undetectable | 6c2mD-1hqsA:13.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hwp | EBULIN (Sambucus ebulus) |
PF00652(Ricin_B_lectin) | 4 | VAL B 193LEU B 143VAL B 171SER B 170 | None | 1.00A | 6c2mD-1hwpB:undetectable | 6c2mD-1hwpB:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i2d | ATP SULFURYLASE (Penicilliumchrysogenum) |
PF01583(APS_kinase)PF01747(ATP-sulfurylase)PF14306(PUA_2) | 4 | VAL A 436HIS A 438VAL A 428SER A 427 | None | 0.94A | 6c2mD-1i2dA:undetectable | 6c2mD-1i2dA:8.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmm | PROTEIN I/IIV-REGION (Streptococcusmutans) |
PF08363(GbpC) | 4 | VAL A 828LEU A 693SER A 818ASP A 512 | None | 0.97A | 6c2mD-1jmmA:undetectable | 6c2mD-1jmmA:11.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1js8 | HEMOCYANIN (Enteroctopusdofleini) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | HIS A2571VAL A2583SER A2587ASP A2580 | CUO A 888 (-3.3A)NoneNoneNone | 0.98A | 6c2mD-1js8A:undetectable | 6c2mD-1js8A:13.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k72 | ENDOGLUCANASE 9G ([Clostridium]cellulolyticum) |
PF00759(Glyco_hydro_9)PF00942(CBM_3) | 4 | PHE A 322LEU A 314SER A 359ASP A 350 | None | 0.86A | 6c2mD-1k72A:undetectable | 6c2mD-1k72A:10.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k8q | TRIACYLGLYCEROLLIPASE, GASTRIC (Canis lupus) |
PF00561(Abhydrolase_1) | 4 | VAL A 185LEU A 68VAL A 269SER A 268 | C11 A2001 ( 4.9A)C11 A2001 ( 4.8A)NoneNone | 0.99A | 6c2mD-1k8qA:undetectable | 6c2mD-1k8qA:12.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l0w | ASPARTYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon)PF02938(GAD) | 4 | VAL A 150HIS A 148LEU A 535ASP A 530 | None | 0.76A | 6c2mD-1l0wA:undetectable | 6c2mD-1l0wA:8.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m1c | MAJOR COAT PROTEIN (Saccharomycescerevisiaevirus L-A) |
PF09220(LA-virus_coat) | 4 | VAL A 155HIS A 154ASP A 152VAL A 304 | None | 0.97A | 6c2mD-1m1cA:undetectable | 6c2mD-1m1cA:8.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m6s | L-ALLO-THREONINEALDOLASE (Thermotogamaritima) |
PF01212(Beta_elim_lyase) | 4 | VAL A 76HIS A 101LEU A 95VAL A 89 | None | 0.98A | 6c2mD-1m6sA:undetectable | 6c2mD-1m6sA:12.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ns3 | NS3 PROTEASE (Hepacivirus C) |
PF02907(Peptidase_S29) | 6 | PHE A 43VAL A 55ASP A 81LEU A 135VAL A 158ASP A 168 | None | 0.67A | 6c2mD-1ns3A:30.4 | 6c2mD-1ns3A:39.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1orp | ENDONUCLEASE III (Geobacillusstearothermophilus) |
PF00633(HHH)PF00730(HhH-GPD) | 4 | VAL A 142HIS A 141ASP A 139VAL A 127 | None | 1.00A | 6c2mD-1orpA:undetectable | 6c2mD-1orpA:16.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p3w | CYSTEINE DESULFURASE (Escherichiacoli) |
no annotation | 4 | ASP B 8LEU B 313VAL B 303SER B 304 | None | 1.00A | 6c2mD-1p3wB:undetectable | 6c2mD-1p3wB:12.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qpi | PROTEIN(TETRACYCLINEREPRESSOR) (Escherichiacoli) |
PF00440(TetR_N)PF02909(TetR_C) | 4 | VAL A 99HIS A 100LEU A 16VAL A 9 | NoneIMD A 1 (-4.0A)NoneNone | 0.83A | 6c2mD-1qpiA:undetectable | 6c2mD-1qpiA:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qu2 | ISOLEUCYL-TRNASYNTHETASE (Staphylococcusaureus) |
PF00133(tRNA-synt_1)PF06827(zf-FPG_IleRS)PF08264(Anticodon_1) | 4 | VAL A 271LEU A 249VAL A 315ASP A 318 | NoneNone A T 73 ( 4.4A)None | 0.99A | 6c2mD-1qu2A:undetectable | 6c2mD-1qu2A:7.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r8w | GLYCEROL DEHYDRATASE (Clostridiumbutyricum) |
PF01228(Gly_radical)PF02901(PFL-like) | 4 | ASP A 538LEU A 49VAL A 208SER A 211 | None | 0.90A | 6c2mD-1r8wA:undetectable | 6c2mD-1r8wA:7.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rqb | TRANSCARBOXYLASE 5SSUBUNIT (Propionibacteriumfreudenreichii) |
PF00682(HMGL-like)PF02436(PYC_OADA) | 4 | HIS A 455LEU A 444VAL A 439ASP A 438 | None | 0.92A | 6c2mD-1rqbA:undetectable | 6c2mD-1rqbA:10.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sc6 | D-3-PHOSPHOGLYCERATEDEHYDROGENASE (Escherichiacoli) |
PF00389(2-Hacid_dh)PF01842(ACT)PF02826(2-Hacid_dh_C) | 4 | PHE A 37VAL A 19HIS A 20SER A 316 | None | 0.75A | 6c2mD-1sc6A:undetectable | 6c2mD-1sc6A:9.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1thg | LIPASE 2 (Galactomycescandidus) |
PF00135(COesterase) | 4 | VAL A 371HIS A 370LEU A 393ASP A 388 | NoneNAG A 990 (-3.4A)NoneNone | 0.84A | 6c2mD-1thgA:undetectable | 6c2mD-1thgA:10.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tkk | SIMILAR TOCHLOROMUCONATECYCLOISOMERASE (Bacillussubtilis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | PHE A 156ASP A 321LEU A 188VAL A 218ASP A 191 | NoneALA A2470 (-2.7A)NoneNone MG A1601 ( 2.7A) | 1.45A | 6c2mD-1tkkA:undetectable | 6c2mD-1tkkA:14.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u0t | INORGANICPOLYPHOSPHATE/ATP-NAD KINASE (Mycobacteriumtuberculosis) |
PF01513(NAD_kinase) | 4 | VAL A 128HIS A 127LEU A 8VAL A 11 | None | 0.95A | 6c2mD-1u0tA:undetectable | 6c2mD-1u0tA:16.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ug1 | KIAA1010 PROTEIN (Homo sapiens) |
PF07653(SH3_2) | 4 | PHE A 72VAL A 68LEU A 41ASP A 60 | None | 0.94A | 6c2mD-1ug1A:undetectable | 6c2mD-1ug1A:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ws0 | PEPTIDE DEFORMYLASE1 (Bacillus cereus) |
PF01327(Pep_deformylase) | 4 | PHE A 142LEU A 137VAL A 54SER A 55 | None | 1.00A | 6c2mD-1ws0A:undetectable | 6c2mD-1ws0A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xip | NUCLEOPORIN NUP159 (Saccharomycescerevisiae) |
PF16755(NUP214) | 4 | VAL A 281LEU A 368VAL A 52ASP A 43 | None | 0.99A | 6c2mD-1xipA:undetectable | 6c2mD-1xipA:10.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xx6 | THYMIDINE KINASE (Clostridiumacetobutylicum) |
PF00265(TK) | 4 | LEU A 25VAL A 56SER A 57ASP A 54 | NoneNoneADP A 301 (-3.1A)None | 0.90A | 6c2mD-1xx6A:undetectable | 6c2mD-1xx6A:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y1p | ALDEHYDE REDUCTASEII (Sporidiobolussalmonicolor) |
PF01370(Epimerase) | 5 | VAL A 129HIS A 90LEU A 255VAL A 248SER A 249 | None | 1.49A | 6c2mD-1y1pA:undetectable | 6c2mD-1y1pA:13.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zrz | PROTEIN KINASE C,IOTA (Homo sapiens) |
PF00069(Pkinase)PF00433(Pkinase_C) | 4 | VAL A 296HIS A 295LEU A 357VAL A 425 | None | 0.91A | 6c2mD-1zrzA:0.0 | 6c2mD-1zrzA:13.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ass | S-PHASEKINASE-ASSOCIATEDPROTEIN 2 (Homo sapiens) |
PF12937(F-box-like) | 4 | LEU B2198VAL B2192SER B2191ASP B2171 | None | 0.98A | 6c2mD-2assB:undetectable | 6c2mD-2assB:11.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cev | PROTEIN (ARGINASE) ([Bacillus]caldovelox) |
PF00491(Arginase) | 5 | VAL A 198HIS A 196ASP A 199LEU A 230SER A 233 | NoneNoneGAI A1003 (-3.8A)NoneNone | 1.43A | 6c2mD-2cevA:undetectable | 6c2mD-2cevA:12.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4v | ISOCITRATEDEHYDROGENASE (Acidithiobacillusthiooxidans) |
PF00180(Iso_dh) | 4 | VAL A 116VAL A 201SER A 202ASP A 158 | None | 0.97A | 6c2mD-2d4vA:undetectable | 6c2mD-2d4vA:11.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dmz | INAD-LIKE PROTEIN (Homo sapiens) |
PF00595(PDZ) | 4 | VAL A 87HIS A 85LEU A 102VAL A 67 | None | 0.88A | 6c2mD-2dmzA:undetectable | 6c2mD-2dmzA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e80 | CYTOCHROME C-552 (Wolinellasuccinogenes) |
PF02335(Cytochrom_C552) | 4 | HIS A 277ASP A 279LEU A 319SER A 325 | NO2 A 704 ( 3.6A)HEM A1511 ( 4.0A)HEM A1511 (-4.6A)None | 0.84A | 6c2mD-2e80A:undetectable | 6c2mD-2e80A:11.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2et6 | (3R)-HYDROXYACYL-COADEHYDROGENASE (Candidatropicalis) |
PF00106(adh_short) | 4 | VAL A 11HIS A 93LEU A 26VAL A 62 | None | 0.92A | 6c2mD-2et6A:undetectable | 6c2mD-2et6A:9.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hsn | GU4 NUCLEIC-BINDINGPROTEIN 1 (Saccharomycescerevisiae) |
no annotation | 5 | VAL B 52HIS B 99LEU B 37VAL B 70ASP B 69 | None | 1.46A | 6c2mD-2hsnB:undetectable | 6c2mD-2hsnB:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i4a | THIOREDOXIN (Acetobacteraceti) |
PF00085(Thioredoxin) | 4 | VAL A 72LEU A 80VAL A 55ASP A 26 | None | 0.98A | 6c2mD-2i4aA:undetectable | 6c2mD-2i4aA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ihy | ABC TRANSPORTER,ATP-BINDING PROTEIN (Staphylococcusaureus) |
PF00005(ABC_tran) | 4 | VAL A 76LEU A 45VAL A 83SER A 84 | None | 0.91A | 6c2mD-2ihyA:undetectable | 6c2mD-2ihyA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l2g | IGF2R DOMAIN 11 (Monodelphisdomestica) |
PF00878(CIMR) | 4 | PHE A1654LEU A1604SER A1526ASP A1601 | None | 0.86A | 6c2mD-2l2gA:undetectable | 6c2mD-2l2gA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lpu | KMATG10 (Kluyveromycesmarxianus) |
PF03987(Autophagy_act_C) | 4 | VAL A 55HIS A 54ASP A 53SER A 101 | None | 0.80A | 6c2mD-2lpuA:undetectable | 6c2mD-2lpuA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mtg | LA-RELATED PROTEIN 6 (Homo sapiens) |
no annotation | 4 | VAL A 213HIS A 216LEU A 187ASP A 190 | None | 0.90A | 6c2mD-2mtgA:undetectable | 6c2mD-2mtgA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o3e | NEUROLYSIN (Rattusnorvegicus) |
PF01432(Peptidase_M3) | 4 | HIS A 425LEU A 509VAL A 504SER A 620 | None | 0.88A | 6c2mD-2o3eA:undetectable | 6c2mD-2o3eA:7.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o4v | PORIN P (Pseudomonasaeruginosa) |
PF07396(Porin_O_P) | 4 | ASP A 258LEU A 185VAL A 167SER A 166 | NoneNoneC8E A1297 (-4.5A)None | 0.95A | 6c2mD-2o4vA:undetectable | 6c2mD-2o4vA:11.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ock | VALACYCLOVIRHYDROLASE (Homo sapiens) |
PF00561(Abhydrolase_1) | 4 | VAL A 230ASP A 227LEU A 129VAL A 143 | None | 0.98A | 6c2mD-2ockA:undetectable | 6c2mD-2ockA:14.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ol3 | ALLOGENEIC H-2KBM8MHC CLASS I MOLECULE (Mus musculus) |
PF00129(MHC_I)PF07654(C1-set) | 4 | LEU H 230VAL H 247SER H 246ASP H 227 | None | 0.98A | 6c2mD-2ol3H:undetectable | 6c2mD-2ol3H:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ovl | PUTATIVE RACEMASE (Streptomycescoelicolor) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | VAL A 134LEU A 123VAL A 350ASP A 303 | None | 0.88A | 6c2mD-2ovlA:undetectable | 6c2mD-2ovlA:12.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qby | CELL DIVISIONCONTROL PROTEIN 6HOMOLOG 3 (Sulfolobussolfataricus) |
PF09079(Cdc6_C)PF13401(AAA_22) | 4 | PHE B 22VAL B 252LEU B 26VAL B 71 | None | 0.98A | 6c2mD-2qbyB:undetectable | 6c2mD-2qbyB:10.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r6r | CELL DIVISIONPROTEIN FTSZ (Aquifexaeolicus) |
PF00091(Tubulin)PF12327(FtsZ_C) | 4 | VAL 1 182ASP 1 183LEU 1 101VAL 1 15 | GDP 1 339 (-4.3A)GDP 1 339 (-3.2A)NoneNone | 0.97A | 6c2mD-2r6r1:undetectable | 6c2mD-2r6r1:14.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rem | DISULFIDEOXIDOREDUCTASE (Xylellafastidiosa) |
PF13462(Thioredoxin_4) | 4 | HIS A 171ASP A 175VAL A 184ASP A 181 | None | 0.90A | 6c2mD-2remA:undetectable | 6c2mD-2remA:17.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v40 | ADENYLOSUCCINATESYNTHETASE ISOZYME 2 (Homo sapiens) |
PF00709(Adenylsucc_synt) | 4 | VAL A 231LEU A 220SER A 192ASP A 183 | None | 0.85A | 6c2mD-2v40A:undetectable | 6c2mD-2v40A:10.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v6b | L-LACTATEDEHYDROGENASE (Deinococcusradiodurans) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | ASP A 197LEU A 113VAL A 142SER A 139 | None | 0.93A | 6c2mD-2v6bA:undetectable | 6c2mD-2v6bA:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x6k | PHOSPHOTIDYLINOSITOL3 KINASE 59F (Drosophilamelanogaster) |
PF00454(PI3_PI4_kinase)PF00613(PI3Ka) | 4 | PHE A 743HIS A 699LEU A 710ASP A 823 | NoneNoneNoneX6K A1951 (-3.5A) | 0.96A | 6c2mD-2x6kA:undetectable | 6c2mD-2x6kA:8.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xfg | ENDOGLUCANASE 1 (Ruminiclostridiumthermocellum) |
PF00759(Glyco_hydro_9) | 4 | PHE A 325LEU A 317SER A 362ASP A 353 | None | 0.88A | 6c2mD-2xfgA:undetectable | 6c2mD-2xfgA:10.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xnd | ATP SYNTHASE SUBUNITDELTA, MITOCHONDRIAL (Bos taurus) |
PF02823(ATP-synt_DE_N) | 4 | VAL H 36HIS H 66LEU H 93VAL H 26 | None | 0.97A | 6c2mD-2xndH:undetectable | 6c2mD-2xndH:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsg | CCMAN5 (Cellulosimicrobiumcellulans) |
PF07971(Glyco_hydro_92) | 5 | VAL A 191ASP A 78LEU A 187VAL A 160ASP A 162 | None | 1.36A | 6c2mD-2xsgA:undetectable | 6c2mD-2xsgA:7.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvg | ALPHA XYLOSIDASE (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF16338(DUF4968)PF17137(DUF5110) | 4 | VAL A 80LEU A 393VAL A 215SER A 216 | None | 1.00A | 6c2mD-2xvgA:undetectable | 6c2mD-2xvgA:6.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ytv | COLD SHOCKDOMAIN-CONTAININGPROTEIN E1 (Homo sapiens) |
PF00313(CSD) | 4 | PHE A 22HIS A 36VAL A 73SER A 74 | None | 1.00A | 6c2mD-2ytvA:undetectable | 6c2mD-2ytvA:27.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z22 | PERIPLASMICPHOSPHATE-BINDINGPROTEIN (Yersinia pestis) |
no annotation | 4 | VAL X 42VAL X 144SER X 147ASP X 56 | NoneNoneNonePO4 X2322 (-2.8A) | 0.99A | 6c2mD-2z22X:undetectable | 6c2mD-2z22X:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z23 | PERIPLASMICOLIGOPEPTIDE-BINDINGPROTEIN (Yersinia pestis) |
PF00496(SBP_bac_5) | 4 | VAL A 509HIS A 508ASP A 42LEU A 224 | None | 0.93A | 6c2mD-2z23A:undetectable | 6c2mD-2z23A:12.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2b | DIHYDROOROTASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 4 | PHE A 292VAL A 164LEU A 237ASP A 240 | NoneNoneNone ZN A 338 (-2.7A) | 0.91A | 6c2mD-2z2bA:undetectable | 6c2mD-2z2bA:14.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3al0 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNITC,LINKER,GLUTAMATE--TRNA LIGASE 2 (Thermotogamaritima;syntheticconstruct) |
PF00749(tRNA-synt_1c)PF02686(Glu-tRNAGln) | 4 | PHE C 304VAL C 307HIS C 311LEU C 288 | None | 0.86A | 6c2mD-3al0C:undetectable | 6c2mD-3al0C:8.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3asm | RIBONUCLEASE HIII (Geobacillusstearothermophilus) |
PF01351(RNase_HII)PF11858(DUF3378) | 4 | LEU A 187VAL A 115SER A 237ASP A 116 | None | 0.94A | 6c2mD-3asmA:undetectable | 6c2mD-3asmA:12.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b2z | ADAMTS-4 (Homo sapiens) |
PF01421(Reprolysin) | 5 | PHE A 316ASP A 351VAL A 324SER A 325ASP A 320 | None | 1.34A | 6c2mD-3b2zA:undetectable | 6c2mD-3b2zA:15.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b95 | EUCHROMATICHISTONE-LYSINEN-METHYLTRANSFERASE1 (Homo sapiens) |
PF12796(Ank_2)PF13637(Ank_4) | 5 | HIS A 907ASP A 909LEU A 945VAL A 954SER A 952 | None | 1.33A | 6c2mD-3b95A:undetectable | 6c2mD-3b95A:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9y | AMMONIUM TRANSPORTERFAMILY RH-LIKEPROTEIN (Nitrosomonaseuropaea) |
PF00909(Ammonium_transp) | 4 | VAL A 320HIS A 321ASP A 316SER A 196 | None | 0.99A | 6c2mD-3b9yA:undetectable | 6c2mD-3b9yA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bxw | CHITINASEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
no annotation | 5 | PHE B 99HIS B 189LEU B 89VAL B 125SER B 85 | None | 1.42A | 6c2mD-3bxwB:undetectable | 6c2mD-3bxwB:12.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c4n | UNCHARACTERIZEDPROTEIN DR_0571 (Deinococcusradiodurans) |
PF01266(DAO) | 4 | ASP A 90LEU A 271VAL A 162ASP A 163 | None | 0.94A | 6c2mD-3c4nA:undetectable | 6c2mD-3c4nA:12.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c65 | UVRABC SYSTEMPROTEIN C (Geobacilluskaustophilus) |
PF08459(UvrC_HhH_N) | 4 | VAL A 399LEU A 511SER A 488ASP A 453 | None | 0.95A | 6c2mD-3c65A:undetectable | 6c2mD-3c65A:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c7k | GUANINENUCLEOTIDE-BINDINGPROTEIN G(O) SUBUNITALPHA (Mus musculus) |
PF00503(G-alpha) | 4 | VAL A 111ASP A 116LEU A 149SER A 152 | NoneNoneNoneGDP A 361 (-3.2A) | 0.96A | 6c2mD-3c7kA:undetectable | 6c2mD-3c7kA:12.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cea | MYO-INOSITOL2-DEHYDROGENASE (Lactobacillusplantarum) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | HIS A 244LEU A 239VAL A 183ASP A 184 | None | 0.94A | 6c2mD-3ceaA:undetectable | 6c2mD-3ceaA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ctp | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Alkaliphilusmetalliredigens) |
PF13377(Peripla_BP_3) | 4 | PHE A 194HIS A 166LEU A 189SER A 153 | None | 0.87A | 6c2mD-3ctpA:undetectable | 6c2mD-3ctpA:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ctz | XAA-PROAMINOPEPTIDASE 1 (Homo sapiens) |
PF00557(Peptidase_M24)PF01321(Creatinase_N)PF16188(Peptidase_M24_C)PF16189(Creatinase_N_2) | 4 | PHE A 444VAL A 447HIS A 451ASP A 482 | None | 0.96A | 6c2mD-3ctzA:undetectable | 6c2mD-3ctzA:9.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cx6 | GUANINENUCLEOTIDE-BINDINGPROTEIN ALPHA-13SUBUNIT (Mus musculus) |
PF00503(G-alpha) | 4 | HIS A 207ASP A 222VAL A 247SER A 248 | None MG A 675 (-2.7A)NoneNone | 0.97A | 6c2mD-3cx6A:undetectable | 6c2mD-3cx6A:12.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3da2 | CARBONIC ANHYDRASE13 (Homo sapiens) |
PF00194(Carb_anhydrase) | 4 | VAL A 257VAL A 113SER A 114ASP A 111 | None | 0.96A | 6c2mD-3da2A:undetectable | 6c2mD-3da2A:12.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dms | ISOCITRATEDEHYDROGENASE [NADP] (Burkholderiapseudomallei) |
PF00180(Iso_dh) | 4 | VAL A 118VAL A 203SER A 204ASP A 160 | None | 0.97A | 6c2mD-3dmsA:undetectable | 6c2mD-3dmsA:11.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ehd | UNCHARACTERIZEDCONSERVED PROTEIN (Enterococcusfaecalis) |
PF05014(Nuc_deoxyrib_tr) | 4 | VAL A 83ASP A 80LEU A 37ASP A 15 | GOL A1001 ( 4.5A)GOL A1001 (-3.0A)NoneNone | 1.00A | 6c2mD-3ehdA:undetectable | 6c2mD-3ehdA:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eix | HTSA PROTEIN (Staphylococcusaureus) |
PF01497(Peripla_BP_2) | 4 | ASP A 81VAL A 301SER A 310ASP A 300 | None | 0.89A | 6c2mD-3eixA:undetectable | 6c2mD-3eixA:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ers | TRNA-BINDING PROTEINYGJH (Escherichiacoli) |
PF01588(tRNA_bind) | 4 | VAL X 109LEU X 83VAL X 95SER X 94 | None | 0.85A | 6c2mD-3ersX:undetectable | 6c2mD-3ersX:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewd | ADENOSINE DEAMINASE (Plasmodiumvivax) |
PF00962(A_deaminase) | 4 | ASP A 310VAL A 306SER A 305ASP A 321 | MCF A 372 (-2.9A)NoneNoneNone | 0.95A | 6c2mD-3ewdA:undetectable | 6c2mD-3ewdA:11.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gv0 | TRANSCRIPTIONALREGULATOR, LACIFAMILY (Agrobacteriumfabrum) |
PF13377(Peripla_BP_3) | 4 | VAL A 270VAL A 279SER A 280ASP A 277 | None | 0.79A | 6c2mD-3gv0A:undetectable | 6c2mD-3gv0A:14.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hrg | UNCHARACTERIZEDPROTEIN BT_3980 WITHACTIN-LIKE ATPASEFOLD (Bacteroidesthetaiotaomicron) |
PF12864(DUF3822) | 4 | PHE A 21VAL A 54LEU A 36ASP A 59 | None | 0.99A | 6c2mD-3hrgA:undetectable | 6c2mD-3hrgA:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hrv | TOXIN COREGULATEDPILIN (Vibrio cholerae) |
PF05946(TcpA) | 4 | PHE A 192VAL A 154SER A 153ASP A 156 | None | 0.82A | 6c2mD-3hrvA:undetectable | 6c2mD-3hrvA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihw | CENTG3 (Homo sapiens) |
PF00071(Ras) | 4 | HIS A 109LEU A 92VAL A 132SER A 137 | None | 0.84A | 6c2mD-3ihwA:undetectable | 6c2mD-3ihwA:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ij3 | CYTOSOLAMINOPEPTIDASE (Coxiellaburnetii) |
PF00883(Peptidase_M17) | 4 | VAL A 172HIS A 171LEU A 259VAL A 224 | None | 0.90A | 6c2mD-3ij3A:undetectable | 6c2mD-3ij3A:9.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j1e | CHAPERONIN BETASUBUNIT (Acidianustengchongensis) |
PF00118(Cpn60_TCP1) | 4 | LEU A 328VAL A 340SER A 341ASP A 350 | None | 0.99A | 6c2mD-3j1eA:undetectable | 6c2mD-3j1eA:9.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jze | DIHYDROOROTASE (Salmonellaenterica) |
PF01979(Amidohydro_1) | 4 | PHE A 303VAL A 175LEU A 248ASP A 251 | NoneNoneNone ZN A 401 (-2.7A) | 0.95A | 6c2mD-3jzeA:undetectable | 6c2mD-3jzeA:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ke6 | PROTEINRV1364C/MT1410 (Mycobacteriumtuberculosis) |
PF07228(SpoIIE)PF13581(HATPase_c_2) | 4 | PHE A 325VAL A 209LEU A 376ASP A 388 | None | 0.97A | 6c2mD-3ke6A:undetectable | 6c2mD-3ke6A:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ktd | PREPHENATEDEHYDROGENASE (Corynebacteriumglutamicum) |
PF02153(PDH) | 4 | VAL A 87HIS A 90VAL A 33SER A 32 | None | 0.93A | 6c2mD-3ktdA:undetectable | 6c2mD-3ktdA:10.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lf4 | FLUORESCENT TIMERPRECURSOR BLUE102FLUORESCENT TIMERPRECURSOR BLUE102 (Discosoma sp.;Discosoma sp.) |
PF01353(GFP)PF01353(GFP) | 4 | PHE A 65VAL A 16HIS A 17SER B 86 | None | 0.94A | 6c2mD-3lf4A:undetectable | 6c2mD-3lf4A:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lif | PUTATIVE DIGUANYLATECYCLASE (GGDEF) WITHPAS/PAC DOMAIN (Rhodopseudomonaspalustris) |
PF02743(dCache_1) | 4 | HIS A 45LEU A 261VAL A 251SER A 252 | None | 0.99A | 6c2mD-3lifA:undetectable | 6c2mD-3lifA:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3llx | PREDICTED AMINO ACIDALDOLASE OR RACEMASE (Idiomarinaloihiensis) |
PF01168(Ala_racemase_N)PF14031(D-ser_dehydrat) | 4 | VAL A 195LEU A 85VAL A 134SER A 133 | None | 0.91A | 6c2mD-3llxA:undetectable | 6c2mD-3llxA:12.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m1c | ENVELOPEGLYCOPROTEIN L (Humanalphaherpesvirus2) |
PF05259(Herpes_UL1)PF12524(GlyL_C) | 5 | PHE B 71ASP B 68VAL B 61SER B 60ASP B 63 | None | 1.42A | 6c2mD-3m1cB:undetectable | 6c2mD-3m1cB:20.00 |