SIMILAR PATTERNS OF AMINO ACIDS FOR 6C06_D_FI8D1404_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8a PROTEIN
(ASPARTYL-TRNA
SYNTHETASE)

(Thermococcus
kodakarensis) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		3 ARG A 412
LYS A 415
ARG A 130
 ATP  A 500 (-2.5A)
None
None
 1.33A 6c06D-1b8aA:
0.0		 6c06D-1b8aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d8c MALATE SYNTHASE G

(Escherichia
coli) 		PF01274
(Malate_synthase) 		3 ARG A 408
LYS A 404
ARG A  57
 None
 1.29A 6c06D-1d8cA:
0.0		 6c06D-1d8cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fno PEPTIDASE T

(Salmonella
enterica) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		3 ARG A 292
LYS A 291
ARG A 353
 None
 1.31A 6c06D-1fnoA:
0.0		 6c06D-1fnoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h17 FORMATE
ACETYLTRANSFERASE 1

(Escherichia
coli) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 ARG A 681
LYS A 389
ARG A 313
 None
 1.31A 6c06D-1h17A:
1.3		 6c06D-1h17A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hqk 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE

(Aquifex
aeolicus) 		PF00885
(DMRL_synthase) 		3 ARG A 127
LYS A 135
ARG A  40
 None
 1.25A 6c06D-1hqkA:
0.0		 6c06D-1hqkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ibx DNA FRAGMENTATION
FACTOR 40
CHIMERA OF IGG
BINDING PROTEIN G
AND DNA
FRAGMENTATION FACTOR
45

(Homo sapiens;
Streptococcus
sp.;
Homo sapiens) 		PF02017
(CIDE-N)
PF02017
(CIDE-N) 		3 ARG A  31
LYS A  32
ARG B  43
 None
 1.27A 6c06D-1ibxA:
undetectable		 6c06D-1ibxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmo HEPARIN COFACTOR II

(Homo sapiens) 		PF00079
(Serpin) 		3 ARG A 120
LYS A 123
ARG A 479
 None
 1.34A 6c06D-1jmoA:
0.0		 6c06D-1jmoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus) 		PF01709
(Transcrip_reg) 		3 ARG A  21
LYS A  23
ARG A 108
 None
 1.31A 6c06D-1lfpA:
0.0		 6c06D-1lfpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lla HEMOCYANIN (SUBUNIT
TYPE II)

(Limulus
polyphemus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		3 ARG A 586
LYS A 531
ARG A 502
 None
 1.20A 6c06D-1llaA:
0.0		 6c06D-1llaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o4w PIN (PILT
N-TERMINUS) DOMAIN

(Archaeoglobus
fulgidus) 		no annotation 3 ARG A  51
LYS A  50
ARG A  42
 None
 1.15A 6c06D-1o4wA:
0.0		 6c06D-1o4wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1olt OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE

(Escherichia
coli) 		PF04055
(Radical_SAM)
PF06969
(HemN_C) 		3 ARG A 371
LYS A 375
ARG A 236
 None
 1.20A 6c06D-1oltA:
undetectable		 6c06D-1oltA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p7d INTEGRASE

(Escherichia
virus Lambda) 		PF00589
(Phage_integrase)
PF02899
(Phage_int_SAM_1) 		3 ARG A 291
LYS A 294
ARG A 348
 None
 1.22A 6c06D-1p7dA:
undetectable		 6c06D-1p7dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvr CLPB PROTEIN

(Thermus
thermophilus) 		PF00004
(AAA)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		3 ARG A 342
LYS A 345
ARG A 518
 None
 1.21A 6c06D-1qvrA:
6.1		 6c06D-1qvrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qxp MU-LIKE CALPAIN

(Bos taurus;
Rattus
norvegicus) 		PF00648
(Peptidase_C2)
PF01067
(Calpain_III)
PF13833
(EF-hand_8) 		3 ARG A 390
LYS A 388
ARG A 630
 None
 1.29A 6c06D-1qxpA:
undetectable		 6c06D-1qxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tba TRANSCRIPTION
INITIATION FACTOR
IID 230K CHAIN
TRANSCRIPTION
INITIATION FACTOR
TFIID

(Drosophila
melanogaster;
Saccharomyces
cerevisiae) 		PF09247
(TBP-binding)
PF00352
(TBP) 		3 ARG B 107
LYS B 110
ARG A  53
 None
 1.01A 6c06D-1tbaB:
undetectable		 6c06D-1tbaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u8v GAMMA-AMINOBUTYRATE
METABOLISM
DEHYDRATASE/ISOMERAS
E

(Clostridium
aminobutyricum) 		PF03241
(HpaB)
PF11794
(HpaB_N) 		3 ARG A 238
LYS A 239
ARG A  43
 None
 1.07A 6c06D-1u8vA:
3.4		 6c06D-1u8vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yt8 THIOSULFATE
SULFURTRANSFERASE

(Pseudomonas
aeruginosa) 		PF00581
(Rhodanese) 		3 ARG A 407
LYS A 406
ARG A 492
 None
 1.13A 6c06D-1yt8A:
undetectable		 6c06D-1yt8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ab5 MRNA MATURASE

(Saccharomyces
cerevisiae) 		PF00961
(LAGLIDADG_1) 		3 ARG A 298
LYS A 490
ARG A 502
 SO4  A 603 (-3.8A)
None
None
 1.12A 6c06D-2ab5A:
undetectable		 6c06D-2ab5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bas YKUI PROTEIN

(Bacillus
subtilis) 		PF00563
(EAL)
PF10388
(YkuI_C) 		3 ARG A 361
LYS A 362
ARG A 278
 None
 1.24A 6c06D-2basA:
undetectable		 6c06D-2basA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cul GLUCOSE-INHIBITED
DIVISION PROTEIN
A-RELATED PROTEIN,
PROBABLE
OXIDOREDUCTASE

(Thermus
thermophilus) 		PF01134
(GIDA) 		3 ARG A 197
LYS A 196
ARG A 222
 None
 1.35A 6c06D-2culA:
undetectable		 6c06D-2culA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dht 409AA LONG
HYPOTHETICAL
NADP-DEPENDENT
ISOCITRATE
DEHYDROGENASE

(Sulfurisphaera
tokodaii) 		PF00180
(Iso_dh) 		3 ARG A  79
LYS A 109
ARG A 149
 None
 1.15A 6c06D-2dhtA:
undetectable		 6c06D-2dhtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fcc ENDONUCLEASE V

(Escherichia
virus T4) 		PF03013
(Pyr_excise) 		3 ARG A 125
LYS A 121
ARG A  70
 None
SO4  A 502 (-3.0A)
GOL  A 602 (-3.9A)
 0.93A 6c06D-2fccA:
undetectable		 6c06D-2fccA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ftp HYDROXYMETHYLGLUTARY
L-COA LYASE

(Pseudomonas
aeruginosa) 		PF00682
(HMGL-like) 		3 ARG A 291
LYS A 294
ARG A 279
 None
 1.19A 6c06D-2ftpA:
undetectable		 6c06D-2ftpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i1j MOESIN

(Spodoptera
frugiperda) 		PF00373
(FERM_M)
PF00769
(ERM)
PF09379
(FERM_N)
PF09380
(FERM_C) 		3 ARG A  40
LYS A  35
ARG A 353
 None
 0.75A 6c06D-2i1jA:
undetectable		 6c06D-2i1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i1j MOESIN

(Spodoptera
frugiperda) 		PF00373
(FERM_M)
PF00769
(ERM)
PF09379
(FERM_N)
PF09380
(FERM_C) 		3 ARG A 506
LYS A 553
ARG A 156
 None
 1.37A 6c06D-2i1jA:
undetectable		 6c06D-2i1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2id5 LEUCINE RICH REPEAT
NEURONAL 6A

(Homo sapiens) 		PF07679
(I-set)
PF13306
(LRR_5)
PF13855
(LRR_8) 		3 ARG A 201
LYS A 203
ARG A 245
 None
NAG  A 488 (-3.9A)
None
 1.32A 6c06D-2id5A:
undetectable		 6c06D-2id5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l7b APOLIPOPROTEIN E

(Homo sapiens) 		PF01442
(Apolipoprotein) 		3 ARG A 142
LYS A 146
ARG A 274
 None
 1.06A 6c06D-2l7bA:
1.9		 6c06D-2l7bA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1n TRANSPORT INHIBITOR
RESPONSE 1 PROTEIN

(Arabidopsis
thaliana) 		PF12937
(F-box-like) 		3 ARG B  46
LYS B  47
ARG B 164
 None
 1.12A 6c06D-2p1nB:
undetectable		 6c06D-2p1nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q1f CHONDROITINASE

(Bacteroides
thetaiotaomicron) 		PF02278
(Lyase_8)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt) 		3 ARG A 489
LYS A 492
ARG A 582
 None
 1.34A 6c06D-2q1fA:
undetectable		 6c06D-2q1fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q4a CLAVAMINATE
SYNTHASE-LIKE
PROTEIN AT3G21360

(Arabidopsis
thaliana) 		PF02668
(TauD) 		3 ARG A 316
LYS A 116
ARG A 179
 None
 1.05A 6c06D-2q4aA:
undetectable		 6c06D-2q4aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vq8 RNASE ZF-1A

(Danio rerio) 		PF00074
(RnaseA) 		3 ARG A  58
LYS A  57
ARG A  25
 None
 1.27A 6c06D-2vq8A:
undetectable		 6c06D-2vq8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agb RED CHLOROPHYLL
CATABOLITE
REDUCTASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF06405
(RCC_reductase) 		3 ARG A  91
LYS A  51
ARG A  62
 None
 1.13A 6c06D-3agbA:
undetectable		 6c06D-3agbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bln ACETYLTRANSFERASE
GNAT FAMILY

(Bacillus cereus) 		PF00583
(Acetyltransf_1) 		3 ARG A  77
LYS A  75
ARG A  28
 None
 0.97A 6c06D-3blnA:
undetectable		 6c06D-3blnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eab SPASTIN
CHMP1B

(Homo sapiens;
Homo sapiens) 		no annotation
no annotation 		3 ARG A 176
LYS A 180
ARG G 196
 None
 1.32A 6c06D-3eabA:
3.0		 6c06D-3eabA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3emk GLUCOSE/RIBITOL
DEHYDROGENASE

(Brucella
melitensis) 		PF13561
(adh_short_C2) 		3 ARG A  64
LYS A  68
ARG A 129
 None
 1.05A 6c06D-3emkA:
undetectable		 6c06D-3emkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fwx PEPTIDE DEFORMYLASE

(Vibrio cholerae) 		PF01327
(Pep_deformylase) 		3 ARG A 154
LYS A 151
ARG A 103
 None
 1.19A 6c06D-3fwxA:
undetectable		 6c06D-3fwxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j1c CHAPERONIN ALPHA
SUBUNIT

(Acidianus
tengchongensis) 		PF00118
(Cpn60_TCP1) 		3 ARG A  20
LYS A  24
ARG A  38
 None
 1.09A 6c06D-3j1cA:
undetectable		 6c06D-3j1cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j3i CAPSID PROTEIN

(Penicillium
chrysogenum
virus) 		no annotation 3 ARG A 969
LYS A 971
ARG A 738
 None
 1.35A 6c06D-3j3iA:
undetectable		 6c06D-3j3iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42
PRE-MRNA-PROCESSING
PROTEIN 45
PRE-MRNA-SPLICING
FACTOR CWF15

(Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV)
PF02731
(SKIP_SNW)
PF01423
(LSM) 		3 ARG A 673
LYS h  24
ARG M 218
 G  C  39 ( 3.8A)
None
None
 1.37A 6c06D-3jb9A:
undetectable		 6c06D-3jb9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfl METHIONYL-TRNA
SYNTHETASE

(Leishmania
major) 		PF09334
(tRNA-synt_1g) 		3 ARG A 300
LYS A 285
ARG A 243
 EDO  A 817 ( 4.0A)
EDO  A 817 (-4.1A)
EDO  A 813 (-4.0A)
 1.35A 6c06D-3kflA:
2.1		 6c06D-3kflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kuf FRAGILE X MENTAL
RETARDATION
SYNDROME-RELATED
PROTEIN 1

(Homo sapiens) 		PF05641
(Agenet) 		3 ARG A  84
LYS A  82
ARG A  47
 None
GOL  A 134 (-3.0A)
None
 1.35A 6c06D-3kufA:
undetectable		 6c06D-3kufA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldg PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.472

(Streptococcus
mutans) 		PF01170
(UPF0020)
PF02926
(THUMP) 		3 ARG A 154
LYS A  60
ARG A 167
 None
 1.23A 6c06D-3ldgA:
undetectable		 6c06D-3ldgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3luy PROBABLE CHORISMATE
MUTASE

(Bifidobacterium
adolescentis) 		PF00800
(PDT) 		3 ARG A 244
LYS A 242
ARG A 185
 None
 1.04A 6c06D-3luyA:
undetectable		 6c06D-3luyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbf FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Encephalitozoon
cuniculi) 		PF00274
(Glycolytic) 		3 ARG A  36
LYS A  32
ARG A 125
 None
 1.19A 6c06D-3mbfA:
0.0		 6c06D-3mbfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o07 PYRIDOXINE
BIOSYNTHESIS PROTEIN
SNZ1

(Saccharomyces
cerevisiae) 		PF01680
(SOR_SNZ) 		3 ARG A 165
LYS A 161
ARG A  52
 None
 1.27A 6c06D-3o07A:
undetectable		 6c06D-3o07A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q0g ENOYL-COA HYDRATASE
ECHA8

(Mycobacterium
tuberculosis) 		PF00378
(ECH_1) 		3 ARG A 205
LYS A 208
ARG A 178
 None
 1.20A 6c06D-3q0gA:
3.8		 6c06D-3q0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sbx PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
marinum) 		PF03641
(Lysine_decarbox) 		3 ARG A  98
LYS A  99
ARG A 170
 AMP  A 188 (-3.1A)
AMP  A 188 (-2.6A)
None
 1.21A 6c06D-3sbxA:
undetectable		 6c06D-3sbxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sxf CALMODULIN-DOMAIN
PROTEIN KINASE 1

(Toxoplasma
gondii) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		3 ARG A 145
LYS A 144
ARG A 445
 None
 1.29A 6c06D-3sxfA:
undetectable		 6c06D-3sxfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ti8 NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ARG A 434
LYS A 430
ARG A 152
 None
None
LNV  A 901 (-4.0A)
 1.15A 6c06D-3ti8A:
undetectable		 6c06D-3ti8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vib MTRR

(Neisseria
gonorrhoeae) 		PF00440
(TetR_N)
PF08361
(TetR_C_2) 		3 ARG A 137
LYS A 167
ARG A  98
 None
PO4  A 211 ( 2.6A)
None
 1.27A 6c06D-3vibA:
3.5		 6c06D-3vibA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdj TYPE I PULLULANASE

(Anoxybacillus
sp. LM18-11) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		3 ARG A 241
LYS A 243
ARG A 574
 None
 1.17A 6c06D-3wdjA:
undetectable		 6c06D-3wdjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zn8 SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN

(Sulfolobus
solfataricus) 		PF02978
(SRP_SPB) 		3 ARG M 426
LYS M 429
ARG M 330
 None
 1.23A 6c06D-3zn8M:
undetectable		 6c06D-3zn8M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ags THIOL-DEPENDENT
REDUCTASE 1

(Leishmania
infantum) 		PF13417
(GST_N_3)
PF16865
(GST_C_5) 		3 ARG A   4
LYS A   4
ARG A  25
 None
 1.12A 6c06D-4agsA:
undetectable		 6c06D-4agsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bpc RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE S

(Homo sapiens) 		PF00102
(Y_phosphatase) 		3 ARG A1787
LYS A1789
ARG A1919
 None
 0.85A 6c06D-4bpcA:
undetectable		 6c06D-4bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cem REGULATOR OF
NONSENSE TRANSCRIPTS
2

(Homo sapiens) 		PF02854
(MIF4G) 		3 ARG A 325
LYS A 328
ARG A 141
 None
 1.30A 6c06D-4cemA:
3.0		 6c06D-4cemA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d86 POLY [ADP-RIBOSE]
POLYMERASE 14

(Homo sapiens) 		PF01661
(Macro) 		3 ARG A1113
LYS A1154
ARG A 898
 None
 1.14A 6c06D-4d86A:
undetectable		 6c06D-4d86A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dvg RHO-LIKE SMALL
GTPASE
DIAPHANOUS PROTEIN

(Entamoeba
histolytica;
Entamoeba
histolytica) 		PF00071
(Ras)
PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 ARG B 197
LYS B 198
ARG A  83
 None
 1.02A 6c06D-4dvgB:
0.7		 6c06D-4dvgB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e2i LARGE T ANTIGEN

(Macaca mulatta
polyomavirus 1) 		PF06431
(Polyoma_lg_T_C) 		3 ARG A 548
LYS A 550
ARG A 559
 None
 1.36A 6c06D-4e2iA:
undetectable		 6c06D-4e2iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4exp MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR

(Mus musculus) 		PF00047
(ig) 		3 ARG X 261
LYS X 259
ARG X 197
 None
 1.21A 6c06D-4expX:
undetectable		 6c06D-4expX:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gni PUTATIVE HEAT SHOCK
PROTEIN

(Chaetomium
thermophilum) 		PF00012
(HSP70) 		3 ARG A 268
LYS A 247
ARG A 329
 None
 1.33A 6c06D-4gniA:
undetectable		 6c06D-4gniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h10 ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR-LIKE
PROTEIN 1
CIRCADIAN LOCOMOTER
OUTPUT CYCLES
PROTEIN KAPUT

(Homo sapiens;
Homo sapiens) 		PF00010
(HLH)
PF00010
(HLH) 		3 ARG A  83
LYS A  87
ARG B  82
 None
 1.28A 6c06D-4h10A:
undetectable		 6c06D-4h10A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3j HEPATOCYTE GROWTH
FACTOR
HEPATOCYTE GROWTH
FACTOR BETA CHAIN

(Homo sapiens;
Homo sapiens) 		PF00089
(Trypsin)
PF01403
(Sema)
PF01437
(PSI) 		3 ARG A 630
LYS A 495
ARG B 143
 None
 1.33A 6c06D-4k3jA:
undetectable		 6c06D-4k3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k5y CORTICOTROPIN-RELEAS
ING FACTOR RECEPTOR
1, T4-LYSOZYME
CHIMERIC CONSTRUCT

(Homo sapiens;
Escherichia
virus T4) 		PF00002
(7tm_2)
PF00959
(Phage_lysozyme) 		3 ARG A1008
LYS A1060
ARG A 292
 None
 0.90A 6c06D-4k5yA:
2.1		 6c06D-4k5yA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kw3 NS1

(Human bocavirus) 		no annotation 3 ARG A 148
LYS A  80
ARG A 257
 None
 1.33A 6c06D-4kw3A:
undetectable		 6c06D-4kw3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4me4 METAL DEPENDENT
PHOSPHOHYDROLASE

(Persephonella
marina) 		PF01590
(GAF)
PF01966
(HD) 		3 ARG A  93
LYS A  70
ARG A 101
 None
 1.30A 6c06D-4me4A:
undetectable		 6c06D-4me4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE

(Salmonella
enterica) 		PF04390
(LptE) 		3 ARG B 124
LYS B 150
ARG B  24
 None
 1.27A 6c06D-4n4rB:
undetectable		 6c06D-4n4rB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nkr MOLYBDOPTERIN-GUANIN
E DINUCLEOTIDE
BIOSYNTHESIS PROTEIN
B

(Bacillus
subtilis) 		PF03205
(MobB) 		3 ARG A  64
LYS A  63
ARG A  87
 None
 1.10A 6c06D-4nkrA:
undetectable		 6c06D-4nkrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oxi ENTEROBACTIN
SYNTHETASE COMPONENT
F-RELATED PROTEIN

(Vibrio cholerae) 		PF00501
(AMP-binding) 		3 ARG A 446
LYS A 452
ARG A 110
 GAP  A 601 (-4.3A)
GAP  A 601 (-2.8A)
None
 1.07A 6c06D-4oxiA:
undetectable		 6c06D-4oxiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p6v NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT A

(Vibrio cholerae) 		PF05896
(NQRA)
PF11973
(NQRA_SLBB) 		3 ARG A 115
LYS A 119
ARG A 318
 None
 1.06A 6c06D-4p6vA:
undetectable		 6c06D-4p6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pzk TRNA
(CYTIDINE(34)-2'-O)-
METHYLTRANSFERASE

(Bacillus
anthracis) 		PF00588
(SpoU_methylase) 		3 ARG A  47
LYS A  43
ARG A  34
 None
 1.36A 6c06D-4pzkA:
undetectable		 6c06D-4pzkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qn0 ENDONUCLEASE G,
MITOCHONDRIAL

(Caenorhabditis
elegans) 		PF01223
(Endonuclease_NS) 		3 ARG A 193
LYS A 196
ARG A  65
 None
 0.88A 6c06D-4qn0A:
undetectable		 6c06D-4qn0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rvw ZNUD

(Neisseria
meningitidis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 ARG A 486
LYS A  82
ARG A 232
 None
 1.00A 6c06D-4rvwA:
undetectable		 6c06D-4rvwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9o NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT A

(Vibrio cholerae) 		PF05896
(NQRA)
PF11973
(NQRA_SLBB) 		3 ARG A 115
LYS A 119
ARG A 318
 None
 1.07A 6c06D-4u9oA:
undetectable		 6c06D-4u9oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uv6 APICAL MEROZOITE
ANTIGEN 1

(Plasmodium
knowlesi) 		PF02430
(AMA-1) 		3 ARG A 180
LYS A 237
ARG A  66
 None
 1.33A 6c06D-4uv6A:
undetectable		 6c06D-4uv6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ymk ACYL-COA DESATURASE
1

(Mus musculus) 		PF00487
(FA_desaturase) 		3 ARG A 154
LYS A 158
ARG A 346
 None
 1.24A 6c06D-4ymkA:
undetectable		 6c06D-4ymkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5anb ELONGATION FACTOR TU
GTP-BINDING
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF14492
(EFG_II) 		3 ARG K 250
LYS K 260
ARG K 192
 None
 1.08A 6c06D-5anbK:
undetectable		 6c06D-5anbK:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cr4 SLEEPING BEAUTY
TRANSPOSASE, SB100X

(synthetic
construct) 		PF01498
(HTH_Tnp_Tc3_2)
PF13358
(DDE_3) 		3 ARG A 180
LYS A 176
ARG A 216
 None
GOL  A 314 ( 4.3A)
None
 1.35A 6c06D-5cr4A:
undetectable		 6c06D-5cr4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d79 BERBERINE BRIDGE
ENZYME-LIKE PROTEIN

(Arabidopsis
thaliana) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		3 ARG A 143
LYS A 245
ARG A 420
 None
 1.37A 6c06D-5d79A:
undetectable		 6c06D-5d79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dot CARBAMOYL-PHOSPHATE
SYNTHASE [AMMONIA],
MITOCHONDRIAL

(Homo sapiens) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain)
PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		3 ARG A1129
LYS A1139
ARG A1453
 None
 0.99A 6c06D-5dotA:
undetectable		 6c06D-5dotA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f4b NAD(P)H
DEHYDROGENASE
(QUINONE)

(Brucella
abortus) 		PF03358
(FMN_red) 		3 ARG A 173
LYS A 173
ARG A 184
 None
 0.97A 6c06D-5f4bA:
undetectable		 6c06D-5f4bA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw7 GLUCOSIDASE YGJK

(Escherichia
coli) 		PF01204
(Trehalase) 		3 ARG A 281
LYS A 285
ARG A 295
 None
 1.23A 6c06D-5gw7A:
2.4		 6c06D-5gw7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE

(Corynebacterium
glutamicum) 		PF01474
(DAHP_synth_2) 		3 ARG A 145
LYS A 143
ARG A 181
 None
PEP  A 502 ( 3.8A)
MPD  A 504 ( 4.9A)
 1.24A 6c06D-5hucA:
undetectable		 6c06D-5hucA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ii0 CALCITONIN RECEPTOR

(Homo sapiens) 		PF02793
(HRM) 		3 ARG A  58
LYS A  54
ARG A  45
 None
 1.36A 6c06D-5ii0A:
undetectable		 6c06D-5ii0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kdx METALLOPEPTIDASE

(Pseudomonas
aeruginosa) 		PF13402
(Peptidase_M60) 		3 ARG A 468
LYS A 542
ARG A 582
 None
 1.29A 6c06D-5kdxA:
0.7		 6c06D-5kdxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lj3 PRE-MRNA-SPLICING
FACTOR BUD31

(Saccharomyces
cerevisiae) 		PF01125
(G10) 		3 ARG L   7
LYS L   5
ARG L  31
 None
 1.33A 6c06D-5lj3L:
undetectable		 6c06D-5lj3L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mtj TYROSINE-PROTEIN
KINASE YES

(Mus musculus) 		PF00017
(SH2) 		3 ARG A 186
LYS A 184
ARG A 176
 None
SO4  A 301 (-3.9A)
None
 1.10A 6c06D-5mtjA:
undetectable		 6c06D-5mtjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd1 CAPSID PROTEIN

(Rosellinia
necatrix
quadrivirus 1) 		no annotation 3 ARG B 481
LYS B 106
ARG B 835
 None
 1.36A 6c06D-5nd1B:
undetectable		 6c06D-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o7b PUTATIVE LOW
MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE SLR0328

(Synechocystis
sp. PCC 6803) 		no annotation 3 ARG A  70
LYS A  68
ARG A  53
 None
 1.05A 6c06D-5o7bA:
undetectable		 6c06D-5o7bA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ovu BETA-PROTEOBACTERIA
PROTEASOME HOMOLOGUE

(Cupriavidus
metallidurans) 		no annotation 3 ARG A  29
LYS A  32
ARG A 163
 None
 1.33A 6c06D-5ovuA:
undetectable		 6c06D-5ovuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t1a CHIMERA PROTEIN OF
CC CHEMOKINE
RECEPTOR TYPE 2
ISOFORM B AND
T4-LYSOZYME,LYSOZYME

(Homo sapiens;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		3 ARG A 232
LYS A 239
ARG A 313
 OLC  A1207 (-3.5A)
OLC  A1207 (-3.7A)
None
 1.31A 6c06D-5t1aA:
1.9		 6c06D-5t1aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tbf TRANSLATION
ELONGATION FACTOR

(Vibrio cholerae) 		PF11826
(DUF3346) 		3 ARG A 407
LYS A 404
ARG A 390
 None
 1.14A 6c06D-5tbfA:
undetectable		 6c06D-5tbfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w40 POPP2 PROTEIN

(Ralstonia
solanacearum) 		PF03421
(Acetyltransf_14) 		3 ARG A 322
LYS A 322
ARG A 416
 SCY  A 321 ( 4.0A)
SCY  A 321 ( 3.0A)
IHP  A 501 (-3.5A)
 1.30A 6c06D-5w40A:
undetectable		 6c06D-5w40A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8x LIPID-A-DISACCHARIDE
SYNTHASE

(Escherichia
coli) 		no annotation 3 ARG A  27
LYS A  30
ARG A   5
 None
 1.15A 6c06D-5w8xA:
undetectable		 6c06D-5w8xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi 40S RIBOSOMAL
PROTEIN S4
RIBOSOMAL PROTEIN
S24E, PUTATIVE

(Trichomonas
vaginalis;
Trichomonas
vaginalis) 		PF00900
(Ribosomal_S4e)
PF01479
(S4)
PF08071
(RS4NT)
PF16121
(40S_S4_C)
PF01282
(Ribosomal_S24e) 		3 ARG E  51
LYS E  53
ARG Y  89
 None
 1.25A 6c06D-5xyiE:
undetectable		 6c06D-5xyiE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y58 ATP-DEPENDENT DNA
HELICASE II SUBUNIT
2

(Saccharomyces
cerevisiae) 		no annotation 3 ARG B  41
LYS B  36
ARG B  86
 U  X 290 ( 4.6A)
None
None
 1.17A 6c06D-5y58B:
undetectable		 6c06D-5y58B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT
ALDEHYDE OXIDASE
LARGE SUBUNIT

(Methylobacillus
sp. KY4400;
Methylobacillus
sp. KY4400) 		no annotation
no annotation 		3 ARG C 656
LYS C 655
ARG B 321
 None
 1.19A 6c06D-5y6qC:
undetectable		 6c06D-5y6qC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zmy -

(-) 		no annotation 3 ARG A 173
LYS A 178
ARG A  31
 None
None
TAR  A 401 (-3.2A)
 1.25A 6c06D-5zmyA:
undetectable		 6c06D-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zq4 SIDE

(Legionella
pneumophila) 		no annotation 3 ARG B 351
LYS B 377
ARG B 310
 None
 1.12A 6c06D-5zq4B:
undetectable		 6c06D-5zq4B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aon DIHYDROLIPOYL
DEHYDROGENASE

(Bordetella
pertussis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		3 ARG A 449
LYS A 462
ARG A 397
 None
 1.18A 6c06D-6aonA:
undetectable		 6c06D-6aonA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c66 CRISPR-ASSOCIATED
PROTEIN, CSE1 FAMILY
CRISPR-ASSOCIATED
PROTEIN, CAS5E
FAMILY

(Thermobifida
fusca;
Thermobifida
fusca) 		no annotation
no annotation 		3 ARG A 472
LYS A 476
ARG M 171
 None
 1.02A 6c06D-6c66A:
2.3		 6c06D-6c66A:
undetectable