SIMILAR PATTERNS OF AMINO ACIDS FOR 6BXM_A_SAMA402
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a04 | NITRATE/NITRITERESPONSE REGULATORPROTEIN NARL (Escherichiacoli) |
PF00072(Response_reg)PF00196(GerE) | 5 | LEU A 68GLY A 67LEU A 55ILE A 12ASP A 59 | None | 1.10A | 6bxmA-1a04A:4.9 | 6bxmA-1a04A:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dhr | DIHYDROPTERIDINEREDUCTASE (Rattusnorvegicus) |
PF00106(adh_short) | 5 | GLY A 19LEU A 70VAL A 67ILE A 36ASP A 37 | NoneNoneNoneNoneNAD A 241 (-2.8A) | 1.08A | 6bxmA-1dhrA:2.6 | 6bxmA-1dhrA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e8c | UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATELIGASE (Escherichiacoli) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | PHE A 383GLY A 387VAL A 439ILE A 424ASP A 426 | None | 1.19A | 6bxmA-1e8cA:2.3 | 6bxmA-1e8cA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i2d | ATP SULFURYLASE (Penicilliumchrysogenum) |
PF01583(APS_kinase)PF01747(ATP-sulfurylase)PF14306(PUA_2) | 5 | PHE A 497GLY A 396LEU A 499VAL A 500ILE A 399 | None | 1.05A | 6bxmA-1i2dA:2.6 | 6bxmA-1i2dA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1izo | CYTOCHROME P450152A1 (Bacillussubtilis) |
PF00067(p450) | 5 | SER A 406GLN A 391LEU A 134VAL A 133ASP A 130 | None | 1.06A | 6bxmA-1izoA:undetectable | 6bxmA-1izoA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l8t | AMINOGLYCOSIDE3'-PHOSPHOTRANSFERASE (Enterococcusfaecalis) |
PF01636(APH) | 5 | GLY A 192LEU A 240VAL A 238ILE A 228ASP A 231 | NoneNoneNoneNoneKAN A 1 ( 4.9A) | 1.06A | 6bxmA-1l8tA:undetectable | 6bxmA-1l8tA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lnz | SPO0B-ASSOCIATEDGTP-BINDING PROTEIN (Bacillussubtilis) |
PF01018(GTP1_OBG)PF01926(MMR_HSR1) | 5 | LEU A 300GLN A 277LEU A 163ILE A 261ASP A 257 | None | 1.15A | 6bxmA-1lnzA:2.1 | 6bxmA-1lnzA:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m5h | FORMYLMETHANOFURAN--TETRAHYDROMETHANOPTERINFORMYLTRANSFERASE (Archaeoglobusfulgidus) |
PF01913(FTR)PF02741(FTR_C) | 5 | LEU A 286GLY A 287SER A 46ILE A 18ASP A 17 | None | 1.10A | 6bxmA-1m5hA:undetectable | 6bxmA-1m5hA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oh9 | ACETYLGLUTAMATEKINASE (Escherichiacoli) |
PF00696(AA_kinase) | 5 | LEU A 9VAL A 41ARG A 36ILE A 6ASP A 175 | None | 1.18A | 6bxmA-1oh9A:undetectable | 6bxmA-1oh9A:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p31 | UDP-N-ACETYLMURAMATE--ALANINE LIGASE (Haemophilusinfluenzae) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | LEU A 419LEU A 444VAL A 443ILE A 432ASP A 430 | None | 1.07A | 6bxmA-1p31A:4.4 | 6bxmA-1p31A:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgj | PEROXIDASE N (Arabidopsisthaliana) |
PF00141(peroxidase) | 5 | LEU A 53SER A 105VAL A 22ILE A 80ASP A 78 | None | 1.16A | 6bxmA-1qgjA:undetectable | 6bxmA-1qgjA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1reg | T4 REGA (Escherichiavirus T4) |
PF01818(Translat_reg) | 5 | LYS X 117CYH X 36ARG X 71ILE X 74ASP X 72 | None | 1.16A | 6bxmA-1regX:undetectable | 6bxmA-1regX:16.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1snz | ALDOSE 1-EPIMERASE (Homo sapiens) |
PF01263(Aldose_epim) | 5 | PHE A 304LEU A 234GLY A 231LEU A 269ASP A 191 | None | 1.17A | 6bxmA-1snzA:undetectable | 6bxmA-1snzA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tc5 | PROBABLE EUKARYOTICD-AMINO ACID TRNADEACYLASE,LMAJ005534AAA (Leishmaniamajor) |
PF02580(Tyr_Deacylase) | 5 | GLY A 103LEU A 65ARG A 12ILE A 11ASP A 193 | None | 1.11A | 6bxmA-1tc5A:undetectable | 6bxmA-1tc5A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v6a | L-LACTATEDEHYDROGENASE ACHAIN (Cyprinus carpio) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | GLY A 160LEU A 109VAL A 110ILE A 142ASP A 141 | None | 1.21A | 6bxmA-1v6aA:3.7 | 6bxmA-1v6aA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a3l | AMP DEAMINASE (Arabidopsisthaliana) |
PF00962(A_deaminase) | 5 | PHE A 479LEU A 429VAL A 432ARG A 476ASP A 449 | None | 1.01A | 6bxmA-2a3lA:undetectable | 6bxmA-2a3lA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2au1 | IGG-DEGRADINGPROTEASE (Streptococcuspyogenes) |
PF09028(Mac-1) | 5 | LEU A 323GLY A 324SER A 285LEU A 93ASP A 174 | None | 1.00A | 6bxmA-2au1A:undetectable | 6bxmA-2au1A:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bf6 | EXO-ALPHA-SIALIDASE (Clostridiumperfringens) |
PF13088(BNR_2) | 5 | GLY A 569LEU A 343ARG A 479ILE A 480ASP A 501 | None | 1.22A | 6bxmA-2bf6A:undetectable | 6bxmA-2bf6A:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c11 | MEMBRANE COPPERAMINE OXIDASE (Homo sapiens) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 5 | LEU A 608GLY A 702LEU A 359VAL A 360ILE A 363 | None | 0.93A | 6bxmA-2c11A:undetectable | 6bxmA-2c11A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d5w | PEPTIDE ABCTRANSPORTER,PEPTIDE-BINDINGPROTEIN (Thermusthermophilus) |
PF00496(SBP_bac_5) | 5 | GLY A 291SER A 282LEU A 275ILE A 295ASP A 294 | None | 1.08A | 6bxmA-2d5wA:2.6 | 6bxmA-2d5wA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dg2 | APOLIPOPROTEIN A-IBINDING PROTEIN (Mus musculus) |
PF03853(YjeF_N) | 5 | LEU A 56GLY A 230VAL A 154CYH A 61ASP A 188 | None | 1.04A | 6bxmA-2dg2A:3.4 | 6bxmA-2dg2A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e3d | UTP--GLUCOSE-1-PHOSPHATEURIDYLYLTRANSFERASE (Escherichiacoli) |
PF00483(NTP_transferase) | 5 | LEU A 120GLY A 116SER A 165ILE A 245ASP A 243 | None | 1.24A | 6bxmA-2e3dA:undetectable | 6bxmA-2e3dA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fj0 | CARBOXYLIC ESTERHYDROLASE (Manduca sexta) |
PF00135(COesterase) | 5 | LEU A 137GLY A 136LEU A 203ARG A 216ASP A 218 | None | 1.06A | 6bxmA-2fj0A:undetectable | 6bxmA-2fj0A:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i80 | D-ALANINE-D-ALANINELIGASE (Staphylococcusaureus) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 5 | GLY A 70LEU A 108ARG A 50ILE A 43ASP A 48 | None | 1.21A | 6bxmA-2i80A:3.3 | 6bxmA-2i80A:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iht | CARBOXYETHYLARGININESYNTHASE (Streptomycesclavuligerus) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | LEU A 495GLY A 494LEU A 459VAL A 486ASP A 463 | TPP A 600 ( 4.3A)TPP A 600 (-3.2A)NoneNone MG A 601 ( 2.8A) | 1.20A | 6bxmA-2ihtA:3.1 | 6bxmA-2ihtA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j6i | FORMATEDEHYDROGENASE ([Candida]boidinii) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | GLY A 250LEU A 132VAL A 133ARG A 277ASP A 158 | None | 1.19A | 6bxmA-2j6iA:3.2 | 6bxmA-2j6iA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o2z | HYPOTHETICAL PROTEIN (Bacillushalodurans) |
PF01933(UPF0052) | 5 | LEU A 93GLY A 91SER A 129VAL A 35ARG A 58 | NoneNoneNoneNoneSO4 A 323 (-3.8A) | 1.26A | 6bxmA-2o2zA:undetectable | 6bxmA-2o2zA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qm3 | PREDICTEDMETHYLTRANSFERASE (Pyrococcusfuriosus) |
PF01861(DUF43) | 5 | LEU A 155GLY A 156LEU A 140VAL A 138ASP A 159 | NoneNoneNoneNone CA A 350 ( 4.5A) | 1.26A | 6bxmA-2qm3A:3.2 | 6bxmA-2qm3A:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qq4 | IRON-SULFUR CLUSTERBIOSYNTHESIS PROTEINISCU (Thermusthermophilus) |
PF01592(NifU_N) | 5 | GLY A 40LEU A 119VAL A 116CYH A 125ILE A 66 | NoneNoneNone ZN A 139 (-2.3A)None | 1.21A | 6bxmA-2qq4A:undetectable | 6bxmA-2qq4A:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v5i | SALMONELLATYPHIMURIUM DB7155BACTERIOPHAGE DET7TAILSPIKE (unidentifiedphage) |
PF09251(PhageP22-tail) | 5 | PHE A 353VAL A 315ARG A 330ILE A 309ASP A 308 | None | 1.17A | 6bxmA-2v5iA:undetectable | 6bxmA-2v5iA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2we8 | XANTHINEDEHYDROGENASE (Mycolicibacteriumsmegmatis) |
PF02625(XdhC_CoxI)PF13478(XdhC_C) | 5 | LEU A 327LEU A 208VAL A 274ARG A 329ASP A 297 | None | 0.93A | 6bxmA-2we8A:3.3 | 6bxmA-2we8A:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x2i | ALPHA-1,4-GLUCANLYASE ISOZYME 1 (Gracilariopsislemaneiformis) |
PF01055(Glyco_hydro_31) | 6 | LEU A 409GLY A 371VAL A 719ARG A 729ILE A 695ASP A 694 | None | 1.47A | 6bxmA-2x2iA:undetectable | 6bxmA-2x2iA:16.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3asa | LL-DIAMINOPIMELATEAMINOTRANSFERASE (Chlamydiatrachomatis) |
PF00155(Aminotran_1_2) | 5 | PHE A 370LEU A 373GLY A 41LEU A 386ILE A 36 | None | 1.12A | 6bxmA-3asaA:2.5 | 6bxmA-3asaA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3axy | 14-3-3-LIKE PROTEINGF14-C (Oryza sativa) |
PF00244(14-3-3) | 5 | GLY C 173SER C 113LEU C 109VAL C 110ASP C 128 | None | 1.22A | 6bxmA-3axyC:undetectable | 6bxmA-3axyC:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3clh | 3-DEHYDROQUINATESYNTHASE (Helicobacterpylori) |
PF01761(DHQ_synthase) | 5 | LEU A 247GLY A 249LEU A 199ILE A 175ASP A 126 | NoneNoneNoneNoneNAD A 400 (-3.6A) | 1.23A | 6bxmA-3clhA:4.3 | 6bxmA-3clhA:24.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dy5 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | LEU A 817GLY A 818ARG A 692ILE A 691ASP A 690 | None | 1.24A | 6bxmA-3dy5A:undetectable | 6bxmA-3dy5A:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e74 | ALLANTOINASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 5 | PHE A 109LEU A 96LEU A 449VAL A 142ASP A 101 | None | 1.25A | 6bxmA-3e74A:undetectable | 6bxmA-3e74A:23.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fxg | RHAMNONATEDEHYDRATASE (Fusariumgraminearum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 110LEU A 91VAL A 92ILE A 135ASP A 136 | None | 1.07A | 6bxmA-3fxgA:undetectable | 6bxmA-3fxgA:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gs9 | PROTEIN GP18 (Listeriamonocytogenes) |
PF06605(Prophage_tail) | 5 | LEU A 82SER A 59VAL A 70ILE A 86ASP A 85 | NoneNoneNoneNoneMLY A 41 ( 3.9A) | 1.23A | 6bxmA-3gs9A:undetectable | 6bxmA-3gs9A:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hhs | PHENOLOXIDASESUBUNIT 1 (Manduca sexta) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 5 | PHE B 151LEU B 459GLY B 460GLN B 279ASP B 13 | None | 1.14A | 6bxmA-3hhsB:undetectable | 6bxmA-3hhsB:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iv3 | TAGATOSE1,6-DIPHOSPHATEALDOLASE 2 (Streptococcusmutans) |
PF01791(DeoC) | 5 | GLY A 30SER A 284LEU A 55VAL A 56ASP A 70 | None | 1.15A | 6bxmA-3iv3A:undetectable | 6bxmA-3iv3A:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jrk | TAGATOSE1,6-DIPHOSPHATEALDOLASE 2 (Streptococcuspyogenes) |
PF01791(DeoC) | 5 | GLY A 26SER A 280LEU A 51VAL A 52ASP A 66 | GOL A 323 ( 4.3A)NoneNoneNoneNone | 1.10A | 6bxmA-3jrkA:undetectable | 6bxmA-3jrkA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k40 | AROMATIC-L-AMINO-ACID DECARBOXYLASE (Drosophilamelanogaster) |
PF00282(Pyridoxal_deC) | 5 | LEU A 350GLY A 351GLN A 145LEU A 153ARG A 352 | None | 1.09A | 6bxmA-3k40A:2.5 | 6bxmA-3k40A:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lp9 | LS-24 (Lathyrussativus) |
PF00045(Hemopexin) | 5 | GLY A 100LEU A 134CYH A 83ILE A 104ASP A 106 | None | 0.85A | 6bxmA-3lp9A:undetectable | 6bxmA-3lp9A:20.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3lzd | DPH2 (Pyrococcushorikoshii) |
PF01866(Diphthamide_syn) | 8 | LEU A 161GLY A 162SER A 236LYS A 238GLN A 241VAL A 269CYH A 287ARG A 289 | SO4 A 344 (-3.8A)SO4 A 344 (-3.5A)NoneNoneSF4 A 343 ( 4.4A)NoneSF4 A 343 (-2.3A)SO4 A 344 (-4.0A) | 0.56A | 6bxmA-3lzdA:20.1 | 6bxmA-3lzdA:38.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3lzd | DPH2 (Pyrococcushorikoshii) |
PF01866(Diphthamide_syn) | 7 | LEU A 161GLY A 162SER A 236LYS A 238VAL A 269ARG A 289ASP A 293 | SO4 A 344 (-3.8A)SO4 A 344 (-3.5A)NoneNoneNoneSO4 A 344 (-4.0A)None | 0.87A | 6bxmA-3lzdA:20.1 | 6bxmA-3lzdA:38.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mca | ELONGATION FACTOR 1ALPHA-LIKE PROTEIN (Schizosaccharomycespombe) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3) | 5 | LEU A 521GLY A 522LEU A 436ILE A 409ASP A 410 | None | 1.14A | 6bxmA-3mcaA:2.7 | 6bxmA-3mcaA:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mv3 | COATOMER SUBUNITALPHA (Saccharomycescerevisiae) |
PF06957(COPI_C) | 5 | LEU A 987GLY A 986LEU A 914VAL A 915ILE A 946 | None | 1.11A | 6bxmA-3mv3A:undetectable | 6bxmA-3mv3A:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3myo | TAGATOSE1,6-DIPHOSPHATEALDOLASE 1 (Streptococcuspyogenes) |
PF01791(DeoC) | 5 | GLY A 29SER A 283LEU A 54VAL A 55ASP A 69 | None | 1.16A | 6bxmA-3myoA:undetectable | 6bxmA-3myoA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pxx | CARVEOLDEHYDROGENASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 5 | GLY A 66VAL A 11ARG A 67ILE A 33ASP A 32 | None | 1.22A | 6bxmA-3pxxA:2.5 | 6bxmA-3pxxA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7c | CARVEOLDEHYDROGENASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 5 | GLY A 67LEU A 101ARG A 68ILE A 34ASP A 33 | None | 1.06A | 6bxmA-3t7cA:undetectable | 6bxmA-3t7cA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tdf | DIHYDRODIPICOLINATESYNTHASE (Acinetobacterbaumannii) |
PF00701(DHDPS) | 5 | LEU A 101GLY A 76LEU A 27VAL A 28ILE A 63 | None | 1.26A | 6bxmA-3tdfA:undetectable | 6bxmA-3tdfA:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqh | QUINONEOXIDOREDUCTASE (Coxiellaburnetii) |
PF08240(ADH_N)PF13602(ADH_zinc_N_2) | 5 | GLY A 160GLN A 168LEU A 278VAL A 279ILE A 286 | NDP A 500 (-3.6A)NoneNoneNoneNone | 1.20A | 6bxmA-3tqhA:4.9 | 6bxmA-3tqhA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ttg | PUTATIVEAMINOMETHYLTRANSFERASE (Leptospirillumrubarum) |
PF01571(GCV_T)PF08669(GCV_T_C) | 5 | PHE A 176LEU A 144GLY A 147SER A 23ASP A 174 | None | 1.26A | 6bxmA-3ttgA:undetectable | 6bxmA-3ttgA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ue3 | SEPTUM FORMATION,PENICILLIN BINDINGPROTEIN 3,PEPTIDOGLYCANSYNTHETASE (Acinetobactersp. ATCC 27244) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 5 | LEU A 547GLY A 527LEU A 499VAL A 498ILE A 387 | None | 1.18A | 6bxmA-3ue3A:undetectable | 6bxmA-3ue3A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uet | ALPHA-1,3/4-FUCOSIDASE (Bifidobacteriumlongum) |
PF01120(Alpha_L_fucos) | 5 | LEU A 311GLY A 315LEU A 395ARG A 444ILE A 408 | None | 1.24A | 6bxmA-3uetA:undetectable | 6bxmA-3uetA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ux8 | EXCINUCLEASE ABC, ASUBUNIT (Geobacillus sp.Y412MC52) |
PF00005(ABC_tran) | 5 | GLY A 813VAL A 890ARG A 866ILE A 864ASP A 862 | None | 0.97A | 6bxmA-3ux8A:undetectable | 6bxmA-3ux8A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bas | ADP-RIBOSYLATIONFACTOR, PUTATIVE(SMALL GTPASE,PUTATIVE) (Trypanosomabrucei) |
PF00025(Arf) | 5 | LEU A 173GLY A 169LEU A 142VAL A 139ILE A 155 | None | 1.22A | 6bxmA-4basA:2.5 | 6bxmA-4basA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4etp | SPINDLE POLEBODY-ASSOCIATEDPROTEIN VIK1 (Saccharomycescerevisiae) |
PF16796(Microtub_bd) | 5 | LEU B 479LEU B 604VAL B 603ILE B 514ASP B 571 | None | 1.13A | 6bxmA-4etpB:undetectable | 6bxmA-4etpB:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gkp | SPINDLE POLEBODY-ASSOCIATEDPROTEIN VIK1 ([Candida]glabrata) |
PF16796(Microtub_bd) | 5 | LEU A 425LEU A 544VAL A 543ILE A 461ASP A 511 | None | 1.12A | 6bxmA-4gkpA:undetectable | 6bxmA-4gkpA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gys | ALLOPHANATEHYDROLASE (Granulibacterbethesdensis) |
PF01425(Amidase) | 5 | LEU A 113GLY A 114VAL A 207ILE A 77ASP A 75 | None | 1.14A | 6bxmA-4gysA:undetectable | 6bxmA-4gysA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hxq | ARGINASE-1 (Homo sapiens) |
PF00491(Arginase) | 5 | LEU A 31SER A 107VAL A 84ILE A 11ASP A 49 | None | 1.18A | 6bxmA-4hxqA:2.1 | 6bxmA-4hxqA:24.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4il5 | CYSTEINE SYNTHASE (Entamoebahistolytica) |
PF00291(PALP) | 5 | GLY A 23SER A 189VAL A 187ILE A 176ASP A 179 | None | 1.24A | 6bxmA-4il5A:2.8 | 6bxmA-4il5A:25.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jiv | PUTATIVEUNCHARACTERIZEDPROTEIN (Vibrio cholerae) |
PF05488(PAAR_motif) | 5 | GLY D 94VAL D 6ARG D 74ILE D 5ASP D 77 | None | 1.23A | 6bxmA-4jivD:undetectable | 6bxmA-4jivD:15.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jw1 | EFFECTOR PROTEIN B (Legionellapneumophila) |
no annotation | 5 | LEU A 55GLY A 54LEU A 93VAL A 94ILE A 75 | None | 0.90A | 6bxmA-4jw1A:undetectable | 6bxmA-4jw1A:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k90 | EXTRACELLULARMETALLOPROTEINASEMEP (Aspergillusfumigatus) |
PF02128(Peptidase_M36) | 5 | GLY A 613VAL A 567ARG A 584ILE A 587ASP A 585 | NoneNoneNoneNoneNAG B 302 ( 3.0A) | 1.25A | 6bxmA-4k90A:undetectable | 6bxmA-4k90A:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mzy | NICOTINATEPHOSPHORIBOSYLTRANSFERASE (Enterococcusfaecalis) |
PF04095(NAPRTase) | 5 | LEU A 158GLY A 314VAL A 275ILE A 263ASP A 264 | NoneNoneNoneNoneFMT A 520 ( 4.5A) | 1.11A | 6bxmA-4mzyA:undetectable | 6bxmA-4mzyA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n0i | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT A,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF01425(Amidase) | 5 | LEU A 92GLY A 93VAL A 189ILE A 55ASP A 53 | None | 1.13A | 6bxmA-4n0iA:undetectable | 6bxmA-4n0iA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rtf | CHAPERONE PROTEINDNAK (Mycobacteriumtuberculosis) |
PF00012(HSP70) | 5 | LEU D 351GLY D 348LEU D 139ILE D 116ASP D 8 | NoneNoneNoneNoneATP D 601 (-3.6A) | 1.24A | 6bxmA-4rtfD:undetectable | 6bxmA-4rtfD:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u4p | STRUCTURALMAINTENANCE OFCHROMOSOMES PROTEIN4 (Homo sapiens) |
PF06470(SMC_hinge) | 5 | GLY B 597LYS B 607VAL B 645ILE B 643ASP B 641 | None | 1.14A | 6bxmA-4u4pB:undetectable | 6bxmA-4u4pB:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uds | MBDR REGULATOR (Azoarcus sp.CIB) |
PF00440(TetR_N) | 5 | LEU A 113VAL A 111ARG A 138ILE A 74ASP A 76 | None | 1.24A | 6bxmA-4udsA:undetectable | 6bxmA-4udsA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbt | PROBABLEHISTIDINOL-PHOSPHATEAMINOTRANSFERASE (Sinorhizobiummeliloti) |
PF00155(Aminotran_1_2) | 5 | LEU A 116GLY A 117LEU A 191VAL A 192ASP A 166 | None | 1.20A | 6bxmA-4wbtA:2.3 | 6bxmA-4wbtA:25.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wwx | V(D)JRECOMBINATION-ACTIVATING PROTEIN 1 (Mus musculus) |
PF12940(RAG1) | 5 | PHE B 557LEU B 672VAL B 532ILE B 535ASP B 536 | None | 1.20A | 6bxmA-4wwxB:undetectable | 6bxmA-4wwxB:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wy9 | PUTATIVE MCP-TYPESIGNAL TRANSDUCTIONPROTEIN (Campylobacterjejuni) |
PF02743(dCache_1) | 5 | GLY A 181SER A 72LYS A 69ILE A 167ASP A 166 | CL A 402 ( 4.1A)NoneNoneNoneNone | 1.18A | 6bxmA-4wy9A:undetectable | 6bxmA-4wy9A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xi2 | TYROSINE-PROTEINKINASE BTK (Mus musculus) |
PF00017(SH2)PF00018(SH3_1)PF07714(Pkinase_Tyr) | 5 | LEU A 542GLY A 541SER A 564VAL A 568ARG A 544 | None | 1.22A | 6bxmA-4xi2A:undetectable | 6bxmA-4xi2A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xoq | COENZYMEF420:L-GLUTAMATELIGASE (Mycobacteriumtuberculosis) |
PF00881(Nitroreductase) | 5 | LEU A 388GLY A 394SER A 400LEU A 310ILE A 340 | NoneNoneF42 A 501 (-4.9A)NoneNone | 1.15A | 6bxmA-4xoqA:undetectable | 6bxmA-4xoqA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zwj | CHIMERA PROTEIN OFHUMAN RHODOPSIN,MOUSE S-ARRESTIN,AND T4 ENDOLYSIN (Homo sapiens;Mus musculus;Escherichiavirus T4) |
PF00001(7tm_1)PF00339(Arrestin_N)PF00959(Phage_lysozyme)PF02752(Arrestin_C)PF10413(Rhodopsin_N) | 5 | GLY A2298VAL A2150ARG A2176ILE A2175ASP A2031 | None | 1.22A | 6bxmA-4zwjA:undetectable | 6bxmA-4zwjA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a42 | UNCHARACTERIZEDLIPOPROTEIN YFHM (Escherichiacoli) |
PF00207(A2M)PF01835(A2M_N)PF07703(A2M_N_2)PF11974(MG1) | 5 | PHE A 200LEU A 289GLY A 266LEU A 229ARG A 201 | None | 1.16A | 6bxmA-5a42A:undetectable | 6bxmA-5a42A:12.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b4x | REELIN (Mus musculus) |
PF07974(EGF_2) | 5 | PHE A2457GLY A2405LEU A2446ARG A2456ASP A2370 | None | 1.09A | 6bxmA-5b4xA:undetectable | 6bxmA-5b4xA:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b4x | REELIN (Mus musculus) |
PF07974(EGF_2) | 5 | PHE A2639GLY A2604LEU A2628ARG A2638ASP A2567 | None | 1.16A | 6bxmA-5b4xA:undetectable | 6bxmA-5b4xA:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5daj | NALD (Pseudomonasaeruginosa) |
PF00440(TetR_N)PF08361(TetR_C_2) | 5 | PHE A 144LEU A 201VAL A 202CYH A 149ARG A 146 | None | 1.16A | 6bxmA-5dajA:undetectable | 6bxmA-5dajA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7p | CELL DIVISIONCONTROL PROTEINCDC48 (Mycolicibacteriumsmegmatis) |
PF00004(AAA)PF02359(CDC48_N) | 5 | LEU A 640LEU A 570ARG A 644ILE A 617ASP A 615 | None | 1.09A | 6bxmA-5e7pA:2.4 | 6bxmA-5e7pA:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jo9 | RIBITOL2-DEHYDROGENASE (Bradyrhizobiumjaponicum) |
PF00106(adh_short) | 5 | SER A 23LEU A 222VAL A 218ILE A 181ASP A 232 | None | 1.25A | 6bxmA-5jo9A:3.0 | 6bxmA-5jo9A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m5p | PRE-MRNA-SPLICINGHELICASE BRR2 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 5 | LEU A 824GLY A 823LEU A 731VAL A 730ILE A 740 | None | 1.07A | 6bxmA-5m5pA:2.2 | 6bxmA-5m5pA:11.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mb4 | GLCNAC SPECIFICLECTIN (Psathyrella) |
PF13517(VCBS) | 5 | GLY A 295SER A 6LEU A 172ILE A 231ASP A 241 | NoneNoneNoneNone NA A 503 (-2.7A) | 1.20A | 6bxmA-5mb4A:undetectable | 6bxmA-5mb4A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mkk | MULTIDRUG RESISTANCEABC TRANSPORTERATP-BINDING ANDPERMEASE PROTEIN (Thermusthermophilus) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 5 | LEU A 504GLY A 500SER A 557GLN A 537ASP A 529 | None | 1.25A | 6bxmA-5mkkA:undetectable | 6bxmA-5mkkA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqp | GLYCOSIDE HYDROLASEBT_1002 (Bacteroidesthetaiotaomicron) |
no annotation | 5 | PHE A 455LEU A 420ARG A 413ILE A 415ASP A 389 | None | 1.25A | 6bxmA-5mqpA:undetectable | 6bxmA-5mqpA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd1 | CAPSID PROTEIN (Rosellinianecatrixquadrivirus 1) |
no annotation | 5 | PHE B 824LEU B 120VAL B 857CYH B 827ILE B 101 | None | 1.25A | 6bxmA-5nd1B:undetectable | 6bxmA-5nd1B:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o3w | PEPTIDE CYCLASE 1 (Gypsophilavaccaria) |
no annotation | 5 | GLY A 189SER A 179VAL A 176ILE A 158ASP A 171 | None | 1.21A | 6bxmA-5o3wA:undetectable | 6bxmA-5o3wA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o7g | ALPHA/BETA HYDROLASEFAMILY PROTEIN (Bacilluscoagulans) |
no annotation | 5 | LEU A 134GLY A 133GLN A 33VAL A 99ILE A 31 | None | 1.05A | 6bxmA-5o7gA:2.0 | 6bxmA-5o7gA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sy5 | ARYL HYDROCARBONRECEPTOR NUCLEARTRANSLOCATORNEURONAL PASDOMAIN-CONTAININGPROTEIN 1 (Mus musculus;Mus musculus) |
PF00010(HLH)PF00989(PAS)PF14598(PAS_11)PF00010(HLH)PF00989(PAS)PF08447(PAS_3) | 5 | LEU B 172SER A 157GLN B 174LEU B 72ILE B 78 | None | 1.20A | 6bxmA-5sy5B:undetectable | 6bxmA-5sy5B:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vni | PROTEIN TRANSPORTPROTEIN SEC23APROTEIN TRANSPORTPROTEIN SEC24A (Homo sapiens;Homo sapiens) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS)PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | PHE A 189SER A 269LEU A 200ARG A 190ASP B 575 | None | 1.01A | 6bxmA-5vniA:undetectable | 6bxmA-5vniA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xdr | PRE-MRNA-SPLICINGFACTOR ATP-DEPENDENTRNA HELICASE DHX15 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF04408(HA2)PF07717(OB_NTP_bind) | 5 | GLY A 163SER A 420VAL A 418ILE A 430ASP A 431 | ADP A 801 (-3.7A)NoneNoneNoneADP A 801 (-2.5A) | 1.19A | 6bxmA-5xdrA:2.8 | 6bxmA-5xdrA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xya | - (-) |
no annotation | 5 | GLY A1313SER A1384VAL A1376ARG A1379ILE A1317 | None | 1.24A | 6bxmA-5xyaA:1.5 | 6bxmA-5xyaA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yat | MITOCHONDRIALALCOHOLDEHYDROGENASEISOZYME III (Komagataellaphaffii) |
no annotation | 5 | GLY A 186LEU A 237VAL A 234ILE A 203ASP A 204 | None | 1.08A | 6bxmA-5yatA:3.3 | 6bxmA-5yatA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z2e | DIHYDRODIPICOLINATEREDUCTASE (Paenisporosarcinasp. TG-14) |
no annotation | 5 | PHE A 72LEU A 119GLY A 120VAL A 81ILE A 97 | None | 1.05A | 6bxmA-5z2eA:3.6 | 6bxmA-5z2eA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z7h | LYSR FAMILYTRANSCRIPTIONALREGULATOR (Staphylococcusaureus) |
no annotation | 5 | LEU A 177GLY A 225SER A 238GLN A 241ILE A 221 | None | 1.23A | 6bxmA-5z7hA:3.4 | 6bxmA-5z7hA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bxn | DIPHTHAMIDEBIOSYNTHESIS ENZYMEDPH2 (CandidatusMethanoperedensnitroreducens) |
no annotation | 12 | PHE A 58LEU A 157GLY A 158SER A 232LYS A 234GLN A 237LEU A 264VAL A 265CYH A 283ARG A 285ILE A 286ASP A 289 | SAM A 901 ( 3.5A)SAM A 901 (-3.8A)SF4 A 900 ( 3.6A)SAM A 901 ( 3.9A)SAM A 901 (-4.9A)SAM A 901 (-3.0A)SAM A 901 (-4.5A)SAM A 901 (-4.0A)SF4 A 900 ( 2.2A)SAM A 901 (-4.1A)SAM A 901 (-4.7A)SAM A 901 (-3.9A) | 0.22A | 6bxmA-6bxnA:41.7 | 6bxmA-6bxnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cg0 | V(D)JRECOMBINATION-ACTIVATING PROTEIN 1 (Mus musculus) |
no annotation | 5 | LEU A 657SER A 561VAL A 532ILE A 535ASP A 536 | None | 1.01A | 6bxmA-6cg0A:undetectable | 6bxmA-6cg0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gjt | - (-) |
no annotation | 5 | LEU A 216GLY A 215LEU A 164VAL A 165ILE A 211 | None | 1.17A | 6bxmA-6gjtA:undetectable | 6bxmA-6gjtA:undetectable |