SIMILAR PATTERNS OF AMINO ACIDS FOR 6BRD_B_RFPB502_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a6d | THERMOSOME (BETASUBUNIT) (Thermoplasmaacidophilum) |
PF00118(Cpn60_TCP1) | 4 | GLN B 110MET B 80ARG B 515PRO B 119 | None | 1.24A | 6brdB-1a6dB:0.7 | 6brdB-1a6dB:10.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dm3 | BIOSYNTHETICTHIOLASE ACETYLATEDAT CYS89 (Zoogloearamigera) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 4 | GLN A 56LEU A 30ARG A 12PRO A 349 | None | 1.33A | 6brdB-1dm3A:0.0 | 6brdB-1dm3A:11.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ewr | DNA MISMATCH REPAIRPROTEIN MUTS (Thermusaquaticus) |
PF00488(MutS_V)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 4 | GLN A 289VAL A 529LEU A 257PRO A 295 | None | 1.07A | 6brdB-1ewrA:0.0 | 6brdB-1ewrA:8.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f0k | UDP-N-ACETYLGLUCOSAMINE-N-ACETYLMURAMYL-(PENTAPEPTIDE)PYROPHOSPHORYL-UNDECAPRENOLN-ACETYLGLUCOSAMINETRANSFERASE (Escherichiacoli) |
PF03033(Glyco_transf_28)PF04101(Glyco_tran_28_C) | 4 | VAL A 167LEU A 328ARG A 333PRO A 276 | None | 1.29A | 6brdB-1f0kA:1.1 | 6brdB-1f0kA:14.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hvy | THYMIDYLATE SYNTHASE (Homo sapiens) |
PF00303(Thymidylat_synt) | 4 | GLN A 32LEU A 74ARG A 271PRO A 273 | None | 1.21A | 6brdB-1hvyA:0.0 | 6brdB-1hvyA:14.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ion | PROBABLE CELLDIVISION INHIBITORMIND (Pyrococcushorikoshii) |
PF13614(AAA_31) | 4 | VAL A 49LEU A 101ARG A 126PRO A 120 | None | 1.32A | 6brdB-1ionA:0.0 | 6brdB-1ionA:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmz | AMINE DEHYDROGENASE (Pseudomonasputida) |
PF08992(QH-AmDH_gamma)PF09098(Dehyd-heme_bind)PF09099(Qn_am_d_aIII)PF09100(Qn_am_d_aIV)PF14930(Qn_am_d_aII) | 4 | VAL A 386LEU A 38ARG A 43PRO G 76 | NoneNoneHEC A1002 ( 3.0A)None | 1.27A | 6brdB-1jmzA:0.0 | 6brdB-1jmzA:12.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k77 | HYPOTHETICAL PROTEINYGBM (Escherichiacoli) |
PF01261(AP_endonuc_2) | 4 | GLN A 158VAL A 165LEU A 189ARG A 194 | None | 1.16A | 6brdB-1k77A:0.0 | 6brdB-1k77A:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l4i | SFAE PROTEIN (Escherichiacoli) |
PF00345(PapD_N)PF02753(PapD_C) | 4 | VAL A 18MET A 166ARG A 79PRO A 117 | None | 1.26A | 6brdB-1l4iA:0.0 | 6brdB-1l4iA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nne | DNA MISMATCH REPAIRPROTEIN MUTS (Thermusaquaticus) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 4 | GLN A 289VAL A 529LEU A 257PRO A 295 | None | 1.25A | 6brdB-1nneA:undetectable | 6brdB-1nneA:7.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ozh | ACETOLACTATESYNTHASE, CATABOLIC (Klebsiellapneumoniae) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | GLN A 28VAL A 102LEU A 463ARG A 55 | None | 1.21A | 6brdB-1ozhA:undetectable | 6brdB-1ozhA:9.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p22 | F-BOX/WD-REPEATPROTEIN 1A (Homo sapiens) |
PF00400(WD40)PF12937(F-box-like) | 4 | GLN A 437VAL A 395LEU A 497ARG A 464 | None | 1.03A | 6brdB-1p22A:undetectable | 6brdB-1p22A:9.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pie | GALACTOKINASE (Lactococcuslactis) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 4 | GLN A 165VAL A 158MET A 207ARG A 36 | NoneNoneNonePO4 A 401 ( 3.5A) | 1.25A | 6brdB-1pieA:0.1 | 6brdB-1pieA:12.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qmh | RNA 3'-TERMINALPHOSPHATE CYCLASE (Escherichiacoli) |
PF01137(RTC)PF05189(RTC_insert) | 4 | VAL A 121LEU A 197ARG A 249PRO A 132 | None | 1.28A | 6brdB-1qmhA:undetectable | 6brdB-1qmhA:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rgy | BETA-LACTAMASE (Citrobacterfreundii) |
PF00144(Beta-lactamase) | 4 | GLN A 267VAL A 313LEU A 107PRO A 304 | None | 1.17A | 6brdB-1rgyA:undetectable | 6brdB-1rgyA:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sma | MALTOGENIC AMYLASE (Thermus sp.IM6501) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 4 | GLN A 127VAL A 132ARG A 367PRO A 409 | None | 1.30A | 6brdB-1smaA:undetectable | 6brdB-1smaA:9.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t8q | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE,PERIPLASMIC (Escherichiacoli) |
PF03009(GDPD) | 4 | GLN A 208VAL A 76LEU A 215PRO A 175 | GOL A1605 ( 4.5A)NoneNoneNone | 1.20A | 6brdB-1t8qA:undetectable | 6brdB-1t8qA:13.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v7v | CHITOBIOSEPHOSPHORYLASE (Vibrioproteolyticus) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 4 | GLN A 353VAL A 329LEU A 507PRO A 433 | None | 1.10A | 6brdB-1v7vA:undetectable | 6brdB-1v7vA:7.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vpb | PUTATIVE MODULATOROF DNA GYRASE (Bacteroidesthetaiotaomicron) |
PF01523(PmbA_TldD) | 4 | VAL A 400LEU A 349MET A 342ARG A 419 | None | 0.91A | 6brdB-1vpbA:undetectable | 6brdB-1vpbA:11.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygu | LEUKOCYTE COMMONANTIGEN (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | GLN A1094VAL A1119LEU A1039ARG A1145 | None | 1.27A | 6brdB-1yguA:undetectable | 6brdB-1yguA:9.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aaz | THYMIDYLATE SYNTHASE (Cryptococcusneoformans) |
PF00303(Thymidylat_synt) | 4 | GLN A 22LEU A 66ARG A 272PRO A 274 | None | 1.09A | 6brdB-2aazA:undetectable | 6brdB-2aazA:14.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ahw | PUTATIVE ENZYME YDIF (Escherichiacoli) |
PF01144(CoA_trans) | 4 | GLN A 225VAL A 15LEU A 41ARG A 241 | None | 1.16A | 6brdB-2ahwA:undetectable | 6brdB-2ahwA:10.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bll | PROTEIN YFBG (Escherichiacoli) |
PF01370(Epimerase) | 4 | GLN A 533VAL A 603ARG A 510PRO A 395 | None | 1.33A | 6brdB-2bllA:undetectable | 6brdB-2bllA:12.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0j | GALACTOSYLGALACTOSYLXYLOSYLPROTEIN3-BETA-GLUCURONOSYLTRANSFERASE 2 (Homo sapiens) |
PF03360(Glyco_transf_43) | 4 | GLN A 279VAL A 249ARG A 235PRO A 239 | None | 1.18A | 6brdB-2d0jA:undetectable | 6brdB-2d0jA:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2de0 | ALPHA-(1,6)-FUCOSYLTRANSFERASE (Homo sapiens) |
PF14604(SH3_9) | 4 | GLN X 480VAL X 319MET X 232ARG X 337 | None | 1.32A | 6brdB-2de0X:undetectable | 6brdB-2de0X:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fk7 | METHOXY MYCOLIC ACIDSYNTHASE 4 (Mycobacteriumtuberculosis) |
PF02353(CMAS) | 4 | GLN A 36VAL A 27LEU A 54ARG A 246 | None | 1.28A | 6brdB-2fk7A:undetectable | 6brdB-2fk7A:13.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h2q | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Trypanosomacruzi) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 4 | GLN A 239LEU A 282ARG A 479PRO A 481 | None | 1.15A | 6brdB-2h2qA:undetectable | 6brdB-2h2qA:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ime | 2-HYDROXYCHROMENE-2-CARBOXYLATEISOMERASE (Pseudomonasputida) |
PF01323(DSBA) | 4 | GLN A 19VAL A 106MET A 191ARG A 183 | None | 1.13A | 6brdB-2imeA:undetectable | 6brdB-2imeA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2is5 | HYPOTHETICAL PROTEIN (Neisseriameningitidis) |
PF05838(Glyco_hydro_108)PF09374(PG_binding_3) | 4 | GLN A 80VAL A 12LEU A 125PRO A 74 | None | 1.06A | 6brdB-2is5A:undetectable | 6brdB-2is5A:18.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ogs | THERMOSTABLECARBOXYLESTERASEEST50 (Geobacillusstearothermophilus) |
PF00135(COesterase) | 4 | VAL A 273LEU A 284ARG A 282PRO A 230 | VAL A 273 ( 0.6A)LEU A 284 ( 0.6A)ARG A 282 ( 0.6A)PRO A 230 ( 1.1A) | 1.16A | 6brdB-2ogsA:undetectable | 6brdB-2ogsA:11.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pa5 | TYROSINE-PROTEINPHOSPHATASENON-RECEPTOR TYPE 9 (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | VAL A 512LEU A 434ARG A 423PRO A 417 | None | 1.33A | 6brdB-2pa5A:undetectable | 6brdB-2pa5A:14.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pqd | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Agrobacteriumsp.) |
PF00275(EPSP_synthase) | 4 | VAL A 421LEU A 379MET A 284ARG A 382 | None | 1.33A | 6brdB-2pqdA:undetectable | 6brdB-2pqdA:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qf7 | PYRUVATE CARBOXYLASEPROTEIN (Rhizobium etli) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | GLN A 351VAL A 311LEU A 438ARG A 424 | None | 1.11A | 6brdB-2qf7A:undetectable | 6brdB-2qf7A:6.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qz6 | BETA-LACTAMASE (Pseudomonasfluorescens) |
PF00144(Beta-lactamase) | 4 | GLN A 267VAL A 313LEU A 107PRO A 304 | None | 1.27A | 6brdB-2qz6A:undetectable | 6brdB-2qz6A:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r94 | 2-KETO-3-DEOXY-(6-PHOSPHO-)GLUCONATEALDOLASE (Thermoproteustenax) |
PF00701(DHDPS) | 4 | GLN A 90VAL A 214LEU A 102ARG A 109 | None | 1.18A | 6brdB-2r94A:undetectable | 6brdB-2r94A:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rgh | ALPHA-GLYCEROPHOSPHATE OXIDASE (Streptococcussp.) |
PF01266(DAO)PF16901(DAO_C) | 4 | GLN A 465VAL A 35ARG A 86PRO A 97 | None | 1.19A | 6brdB-2rghA:undetectable | 6brdB-2rghA:11.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xe4 | OLIGOPEPTIDASE B (Leishmaniamajor) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 4 | GLN A 713VAL A 596MET A 503PRO A 513 | PGR A1742 ( 3.2A)NonePGR A1764 ( 3.5A)None | 1.21A | 6brdB-2xe4A:undetectable | 6brdB-2xe4A:6.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xym | RNA-DIRECTED RNAPOLYMERASE (Hepacivirus C) |
PF00998(RdRP_3) | 4 | GLN A 414VAL A 454LEU A 384PRO A 417 | None | 1.07A | 6brdB-2xymA:1.4 | 6brdB-2xymA:9.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yq1 | ORF73 (Muridgammaherpesvirus4) |
no annotation | 4 | GLN A 190VAL A 221LEU A 139ARG A 148 | None | 1.17A | 6brdB-2yq1A:undetectable | 6brdB-2yq1A:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yx0 | RADICAL SAM ENZYME (Pyrococcushorikoshii) |
PF04055(Radical_SAM)PF08608(Wyosine_form) | 4 | GLN A 73MET A 159ARG A 169PRO A 142 | None | 1.13A | 6brdB-2yx0A:undetectable | 6brdB-2yx0A:12.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zc7 | BETA-LACTAMASE ACT-1 (Klebsiellapneumoniae) |
PF00144(Beta-lactamase) | 4 | GLN A 267VAL A 313LEU A 107PRO A 304 | None | 1.05A | 6brdB-2zc7A:0.0 | 6brdB-2zc7A:10.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zj9 | AMPC (Escherichiacoli) |
PF00144(Beta-lactamase) | 4 | GLN A 267VAL A 313LEU A 107PRO A 304 | IPA A 362 ( 4.6A)NoneNoneNone | 1.04A | 6brdB-2zj9A:undetectable | 6brdB-2zj9A:14.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zws | NEUTRAL CERAMIDASE (Pseudomonasaeruginosa) |
PF04734(Ceramidase_alk)PF17048(Ceramidse_alk_C) | 4 | GLN A 396VAL A 302LEU A 405ARG A 421 | None | 1.33A | 6brdB-2zwsA:undetectable | 6brdB-2zwsA:8.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a8u | OMEGA-AMINOACID--PYRUVATEAMINOTRANSFERASE (Pseudomonasputida) |
PF00202(Aminotran_3) | 4 | VAL X 279LEU X 187ARG X 378PRO X 197 | None | 1.33A | 6brdB-3a8uX:undetectable | 6brdB-3a8uX:10.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b70 | ENOYL REDUCTASE (Aspergillusterreus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLN A 104VAL A 43MET A 55PRO A 30 | None | 1.17A | 6brdB-3b70A:undetectable | 6brdB-3b70A:13.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bby | UNCHARACTERIZEDGST-LIKE PROTEINYFCF (Escherichiacoli) |
PF13417(GST_N_3)PF14834(GST_C_4) | 4 | GLN A 196VAL A 24LEU A 153ARG A 101 | None | 1.30A | 6brdB-3bbyA:undetectable | 6brdB-3bbyA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eb0 | PUTATIVEUNCHARACTERIZEDPROTEIN (Cryptosporidiumparvum) |
PF00069(Pkinase) | 4 | VAL A 127LEU A 328ARG A 152PRO A 351 | None | 1.32A | 6brdB-3eb0A:undetectable | 6brdB-3eb0A:10.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3go1 | FAB 268-D, LIGHTCHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | GLN L 89LEU L 46ARG L 37PRO L 44 | None | 1.26A | 6brdB-3go1L:undetectable | 6brdB-3go1L:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ibr | BACTERIOPHYTOCHROME (Pseudomonasaeruginosa) |
PF00360(PHY)PF01590(GAF)PF08446(PAS_2) | 4 | VAL A 303MET A 154ARG A 289PRO A 207 | None | 1.31A | 6brdB-3ibrA:undetectable | 6brdB-3ibrA:9.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3il0 | XAA-PROAMINOPEPTIDASEAMINOPEPTIDASE P (Streptococcusthermophilus) |
PF01321(Creatinase_N) | 4 | GLN A 117VAL A 97LEU A 12ARG A 48 | NoneNoneNoneGOL A 129 (-3.7A) | 1.26A | 6brdB-3il0A:undetectable | 6brdB-3il0A:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k2w | BETAINE-ALDEHYDEDEHYDROGENASE (Pseudoalteromonasatlantica) |
PF00171(Aldedh) | 4 | GLN A 327LEU A 278ARG A 281PRO A 374 | None | 1.28A | 6brdB-3k2wA:undetectable | 6brdB-3k2wA:9.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kgb | THYMIDYLATE SYNTHASE1/2 (Encephalitozooncuniculi) |
PF00303(Thymidylat_synt) | 4 | GLN A 11LEU A 54ARG A 250PRO A 252 | None | 1.12A | 6brdB-3kgbA:undetectable | 6brdB-3kgbA:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3khw | POLYMERASE PB2 (Influenza Avirus) |
PF00604(Flu_PB2) | 4 | VAL A 667LEU A 571MET A 603ARG A 597 | None | 1.31A | 6brdB-3khwA:undetectable | 6brdB-3khwA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kjr | DIHYDROFOLATEREDUCTASE/THYMIDYLATE SYNTHASE (Babesia bovis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 4 | GLN A 230LEU A 272ARG A 469PRO A 471 | None | 1.20A | 6brdB-3kjrA:undetectable | 6brdB-3kjrA:9.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n26 | AMINO ACID ABCTRANSPORTER,PERIPLASMIC AMINOACID-BINDING PROTEIN (Chlamydiapneumoniae) |
PF00497(SBP_bac_3) | 4 | VAL A 171LEU A 207ARG A 204PRO A 187 | None | 1.15A | 6brdB-3n26A:undetectable | 6brdB-3n26A:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ndn | O-SUCCINYLHOMOSERINESULFHYDRYLASE (Mycobacteriumtuberculosis) |
PF01053(Cys_Met_Meta_PP) | 4 | GLN A 172VAL A 384LEU A 174PRO A 305 | None | 1.26A | 6brdB-3ndnA:undetectable | 6brdB-3ndnA:11.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3okx | YAEB-LIKE PROTEINRPA0152 (Rhodopseudomonaspalustris) |
PF01980(UPF0066) | 4 | VAL A 140LEU A 37ARG A 82PRO A 105 | NoneSAM A 201 (-4.5A)NoneSAM A 201 (-3.8A) | 1.08A | 6brdB-3okxA:undetectable | 6brdB-3okxA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pb0 | DIHYDRODIPICOLINATESYNTHASE (Thermotogamaritima) |
PF00701(DHDPS) | 4 | GLN A 30VAL A 72LEU A 259PRO A 12 | None | 1.26A | 6brdB-3pb0A:undetectable | 6brdB-3pb0A:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pk0 | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Mycolicibacteriumsmegmatis) |
PF13561(adh_short_C2) | 4 | GLN A 124VAL A 65LEU A 175ARG A 137 | None | 1.17A | 6brdB-3pk0A:undetectable | 6brdB-3pk0A:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rih | SHORT CHAINDEHYDROGENASE ORREDUCTASE (Mycobacteroidesabscessus) |
PF13561(adh_short_C2) | 4 | GLN A 137VAL A 78LEU A 188ARG A 150 | EDO A 278 (-3.8A)NoneNoneNone | 1.33A | 6brdB-3rihA:undetectable | 6brdB-3rihA:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t05 | PYRUVATE KINASE (Staphylococcusaureus) |
PF00224(PK)PF00391(PEP-utilizers)PF02887(PK_C) | 4 | VAL A 7LEU A 233ARG A 204PRO A 218 | None | 1.14A | 6brdB-3t05A:undetectable | 6brdB-3t05A:9.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thw | DNA MISMATCH REPAIRPROTEIN MSH3 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05192(MutS_III) | 4 | GLN B 899VAL B 857LEU B 997MET B 526 | None | 1.23A | 6brdB-3thwB:undetectable | 6brdB-3thwB:6.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u7v | BETA-GALACTOSIDASE (Caulobactervibrioides) |
PF02449(Glyco_hydro_42) | 4 | VAL A 123LEU A 333ARG A 338PRO A 319 | None | 1.33A | 6brdB-3u7vA:undetectable | 6brdB-3u7vA:9.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3um6 | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Plasmodiumfalciparum) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 4 | GLN A 327LEU A 369ARG A 566PRO A 568 | None | 1.24A | 6brdB-3um6A:undetectable | 6brdB-3um6A:7.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wwx | S12 FAMILY PEPTIDASE (Streptomycessp. 82F2) |
PF00144(Beta-lactamase) | 4 | GLN A 98VAL A 206LEU A 287MET A 273 | None | 1.27A | 6brdB-3wwxA:0.1 | 6brdB-3wwxA:13.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zz1 | BETA-D-GLUCOSIDEGLUCOHYDROLASE (Trichodermareesei) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | VAL A 529LEU A 514ARG A 324PRO A 506 | None | 1.19A | 6brdB-3zz1A:undetectable | 6brdB-3zz1A:9.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a6u | OMEGA TRANSAMINASE (Chromobacteriumviolaceum) |
PF00202(Aminotran_3) | 4 | GLN A 380VAL A 236LEU A 439ARG A 366 | None | 1.14A | 6brdB-4a6uA:undetectable | 6brdB-4a6uA:10.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a7w | URIDYLATE KINASE (Helicobacterpylori) |
PF00696(AA_kinase) | 4 | VAL A 228LEU A 125MET A 90ARG A 151 | None | 1.21A | 6brdB-4a7wA:undetectable | 6brdB-4a7wA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f1r | CATABOLITEREPRESSION CONTROLPROTEIN (Pseudomonasaeruginosa) |
PF03372(Exo_endo_phos) | 4 | GLN A 96VAL A 30LEU A 83ARG A 93 | None | 1.33A | 6brdB-4f1rA:undetectable | 6brdB-4f1rA:14.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i7u | DIHYDRODIPICOLINATESYNTHASE (Agrobacteriumsp. H13-3) |
PF00701(DHDPS) | 4 | GLN A 31VAL A 73LEU A 257PRO A 12 | None | 1.24A | 6brdB-4i7uA:undetectable | 6brdB-4i7uA:14.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jbb | PUTATIVE GLUTATHIONES-TRANSFERASE (Klebsiellapneumoniae) |
PF13417(GST_N_3)PF14834(GST_C_4) | 4 | GLN A 196VAL A 24LEU A 153ARG A 101 | None | 1.18A | 6brdB-4jbbA:undetectable | 6brdB-4jbbA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ldp | NDP-FOROSAMYLTRANSFERASE (Saccharopolysporaspinosa) |
PF06722(DUF1205) | 4 | VAL A 53LEU A 184ARG A 149PRO A 137 | None | 1.33A | 6brdB-4ldpA:undetectable | 6brdB-4ldpA:11.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m8u | OLIGO-1,6-GLUCOSIDASE 1 (Bacillussubtilis) |
PF00128(Alpha-amylase)PF16657(Malt_amylase_C) | 4 | GLN A 12VAL A 253MET A 80ARG A 90 | None | 1.25A | 6brdB-4m8uA:undetectable | 6brdB-4m8uA:9.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mbg | CAAXFARNESYLTRANSFERASEALPHA SUBUNIT RAM2 (Aspergillusfumigatus) |
PF01239(PPTA) | 4 | GLN A 235VAL A 227ARG A 245PRO A 247 | None | 1.27A | 6brdB-4mbgA:undetectable | 6brdB-4mbgA:13.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o38 | CYCLIN-G-ASSOCIATEDKINASE (Homo sapiens) |
PF00069(Pkinase) | 4 | GLN A 154VAL A 322LEU A 179MET A 295 | None | 1.29A | 6brdB-4o38A:undetectable | 6brdB-4o38A:11.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o99 | ACETYL-COAACETYLTRANSFERASE (Cupriavidusnecator) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 4 | GLN A 55LEU A 29ARG A 11PRO A 350 | None | 1.31A | 6brdB-4o99A:undetectable | 6brdB-4o99A:12.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pii | N-GLYCOSYLASE/DNALYASE (Pyrococcusfuriosus) |
PF09171(AGOG) | 4 | VAL A 204LEU A 222ARG A 25PRO A 215 | None | 1.27A | 6brdB-4piiA:undetectable | 6brdB-4piiA:13.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rcn | LONG-CHAIN ACYL-COACARBOXYLASE (Mycobacteriumavium) |
PF00289(Biotin_carb_N)PF01039(Carboxyl_trans)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | GLN A 825VAL A 767LEU A 834PRO A 894 | None | 1.05A | 6brdB-4rcnA:undetectable | 6brdB-4rcnA:6.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rh7 | GREEN FLUORESCENTPROTEIN/CYTOPLASMICDYNEIN 2 HEAVY CHAIN1 (Homo sapiens;syntheticconstruct) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | VAL A1484LEU A1705MET A1634ARG A1708 | None | 1.24A | 6brdB-4rh7A:undetectable | 6brdB-4rh7A:2.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tx2 | NON-RIBOSOMALPEPTIDE SYNTHETASE (Actinoplanesteichomyceticus) |
PF00668(Condensation) | 4 | GLN B 264VAL B 365LEU B 312ARG B 273 | None | 1.28A | 6brdB-4tx2B:1.3 | 6brdB-4tx2B:11.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgt | FRQ-INTERACTING RNAHELICASE (Neurosporacrassa) |
PF00270(DEAD)PF00271(Helicase_C)PF08148(DSHCT)PF13234(rRNA_proc-arch) | 4 | GLN A 185VAL A 200ARG A 175PRO A 173 | None | 1.21A | 6brdB-4xgtA:undetectable | 6brdB-4xgtA:5.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xsc | THYMIDYLATE SYNTHASE (Humanalphaherpesvirus3) |
PF00303(Thymidylat_synt) | 4 | GLN A 20LEU A 62ARG A 259PRO A 261 | None | 1.31A | 6brdB-4xscA:undetectable | 6brdB-4xscA:14.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bxi | NUCLEOSIDEDIPHOSPHATE KINASE (Toxoplasmagondii) |
PF00334(NDK) | 4 | GLN A 32VAL A 152LEU A 106ARG A 90 | NoneNoneNoneBCT A 201 ( 4.9A) | 1.17A | 6brdB-5bxiA:undetectable | 6brdB-5bxiA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw5 | T-COMPLEX PROTEIN 1SUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00118(Cpn60_TCP1) | 4 | VAL a 517LEU a 455ARG a 478PRO a 459 | None | 1.28A | 6brdB-5gw5a:undetectable | 6brdB-5gw5a:10.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h3a | ORF70 (Humangammaherpesvirus8) |
PF00303(Thymidylat_synt) | 4 | GLN A 56LEU A 98ARG A 295PRO A 297 | None | 1.15A | 6brdB-5h3aA:undetectable | 6brdB-5h3aA:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k5z | PARA (Sulfolobus sp.NOB8H2) |
PF13614(AAA_31) | 4 | GLN A 48LEU A 60MET A 111PRO A 101 | None | 1.20A | 6brdB-5k5zA:undetectable | 6brdB-5k5zA:13.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k9n | POLYAMINE NACETYLTRANSFERASE (Drosophilamelanogaster) |
PF00583(Acetyltransf_1) | 4 | GLN A 210VAL A 110MET A 147PRO A 35 | None | 1.28A | 6brdB-5k9nA:undetectable | 6brdB-5k9nA:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koh | NITROGENASE FEMOBETA SUBUNIT PROTEINNIFK (Gluconacetobacterdiazotrophicus) |
PF00148(Oxidored_nitro)PF11844(DUF3364) | 4 | VAL B 472LEU B 72ARG B 104PRO B 460 | None | 1.30A | 6brdB-5kohB:undetectable | 6brdB-5kohB:9.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kyu | PROTEIN TRANSPORTPROTEIN SEC24D (Homo sapiens) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 4 | GLN B 653VAL B 633LEU B 799PRO B 614 | None | 1.18A | 6brdB-5kyuB:undetectable | 6brdB-5kyuB:7.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nn8 | LYSOSOMALALPHA-GLUCOSIDASE (Homo sapiens) |
no annotation | 4 | GLN A 553VAL A 547LEU A 476PRO A 522 | None | 1.29A | 6brdB-5nn8A:undetectable | 6brdB-5nn8A:6.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o9w | THEBAINE6-O-DEMETHYLASE (Papaversomniferum) |
no annotation | 4 | VAL A 299LEU A 9MET A 115PRO A 30 | None | 1.22A | 6brdB-5o9wA:undetectable | 6brdB-5o9wA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t0l | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Toxoplasmagondii) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 4 | GLN A 326LEU A 368ARG A 566PRO A 568 | None | 1.13A | 6brdB-5t0lA:undetectable | 6brdB-5t0lA:8.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ty0 | ELONGATION FACTOR G (Legionellapneumophila) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2) | 4 | VAL A 180LEU A 284ARG A 135PRO A 261 | None | 1.20A | 6brdB-5ty0A:undetectable | 6brdB-5ty0A:11.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vef | SERINE/THREONINE-PROTEIN KINASE PAK 4 (Homo sapiens) |
no annotation | 4 | VAL A 476LEU A 308MET A 395ARG A 371 | SEP A 474 ( 4.4A)NoneM77 A 601 ( 2.9A)None | 0.99A | 6brdB-5vefA:1.2 | 6brdB-5vefA:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgl | SOLUBLEACETYLCHOLINERECEPTOR (Aplysiacalifornica) |
no annotation | 4 | VAL A 97LEU A 154ARG A 57PRO A 86 | None | 1.26A | 6brdB-5xglA:undetectable | 6brdB-5xglA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgl | SOLUBLEACETYLCHOLINERECEPTOR (Aplysiacalifornica) |
no annotation | 4 | VAL A 99LEU A 154ARG A 57PRO A 86 | None | 1.17A | 6brdB-5xglA:undetectable | 6brdB-5xglA:18.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6c7s | PUTATIVE RIFAMPINMONOOXYGENASE (Nocardiafarcinica) |
no annotation | 4 | VAL A 93LEU A 176ARG A 201PRO A 283 | NoneFAD A 501 ( 4.6A)NoneRFH A 502 ( 4.2A) | 0.53A | 6brdB-6c7sA:63.3 | 6brdB-6c7sA:74.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d6u | GAMMA-AMINOBUTYRICACID RECEPTORSUBUNITBETA-2,GAMMA-AMINOBUTYRIC ACID RECEPTORSUBUNIT BETA-2GAMMA-AMINOBUTYRICACID RECEPTORSUBUNITGAMMA-2,GAMMA-AMINOBUTYRIC ACID RECEPTORSUBUNIT GAMMA-2 (Homo sapiens) |
no annotation | 4 | VAL A 16LEU E 87ARG E 85PRO E 44 | None | 1.27A | 6brdB-6d6uA:undetectable | 6brdB-6d6uA:14.46 |