SIMILAR PATTERNS OF AMINO ACIDS FOR 6BRD_B_RFPB502_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a2o | CHEB METHYLESTERASE (Salmonellaenterica) |
PF00072(Response_reg)PF01339(CheB_methylest) | 5 | GLY A 230PHE A 104THR A 168GLY A 167GLY A 166 | None | 1.12A | 6brdB-1a2oA:undetectable | 6brdB-1a2oA:12.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bdg | HEXOKINASE (Schistosomamansoni) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 5 | GLY A 179VAL A 180PHE A 154THR A 172GLY A 174 | NoneNoneNoneGLC A 501 (-2.7A)None | 1.21A | 6brdB-1bdgA:0.0 | 6brdB-1bdgA:10.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dab | P.69 PERTACTIN (Bordetellapertussis) |
PF03212(Pertactin) | 5 | HIS A 150GLY A 243VAL A 240GLY A 127GLY A 147 | None | 1.22A | 6brdB-1dabA:undetectable | 6brdB-1dabA:10.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e9y | UREASE SUBUNIT BETA (Helicobacterpylori) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 5 | PHE B 195VAL B 369THR B 171GLY B 159GLY B 160 | NoneNoneKCX B 219 ( 3.0A)NoneNone | 1.01A | 6brdB-1e9yB:undetectable | 6brdB-1e9yB:10.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eww | ANTIFREEZE PROTEIN (Choristoneurafumiferana) |
PF05264(CfAFP) | 5 | GLY A 44VAL A 45THR A 53GLY A 54GLY A 71 | None | 1.04A | 6brdB-1ewwA:undetectable | 6brdB-1ewwA:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j3n | 3-OXOACYL-(ACYL-CARRIER PROTEIN)SYNTHASE II (Thermusthermophilus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | GLY A 8VAL A 6PHE A 405GLY A 164GLY A 344 | None | 1.21A | 6brdB-1j3nA:0.0 | 6brdB-1j3nA:11.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jkm | BREFELDIN A ESTERASE (Bacillussubtilis) |
PF07859(Abhydrolase_3) | 5 | PHE A 40GLY A 339VAL A 337PHE A 29GLY A 41 | None | 1.06A | 6brdB-1jkmA:0.8 | 6brdB-1jkmA:14.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qle | CYTOCHROME C OXIDASEPOLYPEPTIDE I-BETA (Paracoccusdenitrificans) |
PF00115(COX1) | 5 | HIS A 411GLY A 286THR A 384GLY A 387GLY A 386 | HEA A 602 (-3.4A)NoneHEA A 602 ( 4.7A)HEA A 602 (-3.3A)None | 1.22A | 6brdB-1qleA:0.0 | 6brdB-1qleA:9.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qle | CYTOCHROME C OXIDASEPOLYPEPTIDE I-BETA (Paracoccusdenitrificans) |
PF00115(COX1) | 5 | HIS A 411GLY A 423THR A 384GLY A 387GLY A 386 | HEA A 602 (-3.4A)NoneHEA A 602 ( 4.7A)HEA A 602 (-3.3A)None | 1.16A | 6brdB-1qleA:0.0 | 6brdB-1qleA:9.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w18 | LEVANSUCRASE (Gluconacetobacterdiazotrophicus) |
PF02435(Glyco_hydro_68) | 5 | PHE A 180VAL A 240PHE A 282GLY A 200GLY A 201 | None | 1.11A | 6brdB-1w18A:undetectable | 6brdB-1w18A:12.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ybe | NICOTINATEPHOSPHORIBOSYLTRANSFERASE (Agrobacteriumtumefaciens) |
PF04095(NAPRTase) | 5 | PHE A 429VAL A 305PHE A 311THR A 294GLY A 293 | None | 1.06A | 6brdB-1ybeA:undetectable | 6brdB-1ybeA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yr2 | PROLYLOLIGOPEPTIDASE (Novosphingobiumcapsulatum) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 5 | PHE A 498GLY A 582VAL A 584GLY A 497GLY A 527 | None | 1.19A | 6brdB-1yr2A:undetectable | 6brdB-1yr2A:8.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yzy | HYPOTHETICAL PROTEINHI1011 (Haemophilusinfluenzae) |
PF07005(DUF1537)PF17042(DUF1357_C) | 5 | GLY A 90ARG A 50THR A 217GLY A 218GLY A 219 | None | 1.14A | 6brdB-1yzyA:undetectable | 6brdB-1yzyA:12.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cmt | PEPTIDYL-PROLYLCIS-TRANS ISOMERASEE (Schistosomamansoni) |
PF00160(Pro_isomerase) | 5 | GLY A 103VAL A 139GLY A 71GLY A 72MET A 149 | None | 0.93A | 6brdB-2cmtA:undetectable | 6brdB-2cmtA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d6f | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT E (Methanothermobacterthermautotrophicus) |
PF02637(GatB_Yqey)PF02934(GatB_N)PF02938(GAD) | 5 | GLY C 170VAL C 171THR C 127GLY C 128GLY C 129 | None | 1.05A | 6brdB-2d6fC:0.9 | 6brdB-2d6fC:10.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eij | CYTOCHROME C OXIDASESUBUNIT 1 (Bos taurus) |
PF00115(COX1) | 5 | HIS A 376GLY A 250THR A 349GLY A 352GLY A 351 | HEA A 516 (-3.3A)NoneHEA A 516 ( 4.2A)HEA A 516 (-3.5A)None | 1.10A | 6brdB-2eijA:undetectable | 6brdB-2eijA:11.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fel | 3-CARBOXY-CIS,CIS-MUCONATE LACTONIZINGENZYME (Agrobacteriumtumefaciens) |
PF00206(Lyase_1) | 5 | GLY A 314ARG A 231THR A 107GLY A 196GLY A 195 | None | 1.21A | 6brdB-2felA:undetectable | 6brdB-2felA:12.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gdu | SUCROSEPHOSPHORYLASE (Bifidobacteriumadolescentis) |
PF00128(Alpha-amylase)PF09244(DUF1964) | 5 | HIS A 234PHE A 253ARG A 365GLY A 381GLY A 293 | SUC A2064 (-3.9A)NoneNoneNoneNone | 1.09A | 6brdB-2gduA:undetectable | 6brdB-2gduA:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hyk | BETA-1,3-GLUCANASE (Nocardiopsissp. F96) |
PF00722(Glyco_hydro_16) | 5 | HIS A 142ARG A 132GLY A 222GLY A 149GLY A 148 | GOL A 249 ( 4.1A)NoneNoneNoneGOL A 250 ( 3.4A) | 0.99A | 6brdB-2hykA:undetectable | 6brdB-2hykA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nzt | HEXOKINASE-2 (Homo sapiens) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 5 | GLY A 179VAL A 180PHE A 154THR A 172GLY A 174 | NoneNoneNoneGLC A1001 (-2.7A)None | 1.12A | 6brdB-2nztA:undetectable | 6brdB-2nztA:7.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ood | BLR3880 PROTEIN (Bradyrhizobiumdiazoefficiens) |
PF01979(Amidohydro_1) | 5 | GLY A 330VAL A 327PHE A 123THR A 132GLY A 131 | None | 1.17A | 6brdB-2oodA:undetectable | 6brdB-2oodA:12.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qm1 | GLUCOKINASE (Enterococcusfaecalis) |
PF00480(ROK) | 5 | GLY A 192VAL A 193PHE A 226GLY A 267GLY A 266 | None | 1.20A | 6brdB-2qm1A:undetectable | 6brdB-2qm1A:14.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qne | PUTATIVEMETHYLTRANSFERASE (Desulfitobacteriumhafniense) |
PF06253(MTTB) | 5 | GLY A 132PHE A 361THR A 346GLY A 312GLY A 313 | EDO A 477 (-3.2A)NoneNoneNoneNone | 1.11A | 6brdB-2qneA:undetectable | 6brdB-2qneA:8.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v4j | SULFITE REDUCTASE,DISSIMILATORY-TYPESUBUNIT BETA (Desulfovibriovulgaris) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | GLY B 138ARG B 98VAL B 139GLY B 286GLY B 287 | NoneSH0 A 503 (-3.9A)NoneNoneNone | 0.98A | 6brdB-2v4jB:undetectable | 6brdB-2v4jB:11.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v9y | PHOSPHORIBOSYLFORMYLGLYCINAMIDINECYCLO-LIGASE (Homo sapiens) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | GLY A 618THR A 682GLY A 683GLY A 684MET A 519 | None | 1.04A | 6brdB-2v9yA:undetectable | 6brdB-2v9yA:14.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2woc | ADP-RIBOSYL-[DINITROGEN REDUCTASE]GLYCOHYDROLASE (Rhodospirillumrubrum) |
PF03747(ADP_ribosyl_GH) | 5 | GLY A 248VAL A 238THR A 46GLY A 47GLY A 48 | None | 1.06A | 6brdB-2wocA:undetectable | 6brdB-2wocA:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xn1 | ALPHA-GALACTOSIDASE (Lactobacillusacidophilus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 5 | HIS A 203ARG A 377GLY A 372GLY A 532GLY A 533 | GOL A1734 ( 4.4A)NoneNoneGOL A1734 ( 3.3A)TRS A1733 (-4.4A) | 1.17A | 6brdB-2xn1A:undetectable | 6brdB-2xn1A:7.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xt0 | HALOALKANEDEHALOGENASE (Plesiocystispacifica) |
PF00561(Abhydrolase_1) | 5 | MET A 65VAL A 280GLY A 126GLY A 125MET A 257 | None | 0.98A | 6brdB-2xt0A:undetectable | 6brdB-2xt0A:15.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y9x | LECTIN-LIKE FOLDPROTEINPOLYPHENOL OXIDASE (Agaricusbisporus) |
PF00264(Tyrosinase)no annotation | 5 | HIS A 251GLY E 13VAL E 150THR A 87GLY A 245 | None | 1.02A | 6brdB-2y9xA:undetectable | 6brdB-2y9xA:10.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yfn | ALPHA-GALACTOSIDASE-SUCROSE KINASE AGASK ([Ruminococcus]gnavus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 5 | HIS A 199ARG A 373GLY A 368GLY A 520GLY A 521 | None | 1.18A | 6brdB-2yfnA:undetectable | 6brdB-2yfnA:8.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmb | ACETOACETATEDECARBOXYLASE (Methanoculleusmarisnigri) |
PF06314(ADC) | 5 | GLY A 114THR A 9GLY A 19GLY A 18MET A 258 | P33 A 269 ( 4.5A)NoneNoneNoneNone | 1.02A | 6brdB-3cmbA:undetectable | 6brdB-3cmbA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cyv | UROPORPHYRINOGENDECARBOXYLASE (Shigellaflexneri) |
PF01208(URO-D) | 5 | ARG A 27GLY A 328THR A 249GLY A 211GLY A 212 | None | 1.21A | 6brdB-3cyvA:undetectable | 6brdB-3cyvA:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dl0 | ADENYLATE KINASE (Bacillussubtilis) |
PF00406(ADK)PF05191(ADK_lid) | 5 | HIS A 28VAL A 115THR A 15GLY A 14GLY A 17 | NoneNoneAP5 A 218 (-3.6A)AP5 A 218 (-3.7A)None | 1.19A | 6brdB-3dl0A:undetectable | 6brdB-3dl0A:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g8m | SERINEHYDROXYMETHYLTRANSFERASE (Escherichiacoli) |
PF00464(SHMT) | 5 | HIS A 129PHE A 198VAL A 208GLY A 172GLY A 173 | None | 1.13A | 6brdB-3g8mA:undetectable | 6brdB-3g8mA:13.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ij3 | CYTOSOLAMINOPEPTIDASE (Coxiellaburnetii) |
PF00883(Peptidase_M17) | 5 | HIS A 255ARG A 341GLY A 338GLY A 252GLY A 251 | NoneSO4 A 461 ( 3.6A)NoneNoneNone | 1.10A | 6brdB-3ij3A:undetectable | 6brdB-3ij3A:10.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n2x | UNCHARACTERIZEDPROTEIN YAGE (Escherichiacoli) |
PF00701(DHDPS) | 5 | GLY A 240VAL A 242PHE A 208GLY A 214GLY A 215 | None | 1.15A | 6brdB-3n2xA:undetectable | 6brdB-3n2xA:14.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3omn | CYTOCHROME COXIDASE, AA3 TYPE,SUBUNIT I (Rhodobactersphaeroides) |
PF00115(COX1) | 5 | HIS A 419GLY A 431THR A 392GLY A 395GLY A 394 | HEA A 2 (-3.2A)NoneHEA A 2 ( 3.9A)HEA A 2 (-3.4A)None | 1.08A | 6brdB-3omnA:undetectable | 6brdB-3omnA:9.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p5m | ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteriumavium) |
PF00378(ECH_1) | 5 | PHE A 233GLY A 62VAL A 100THR A 126GLY A 129 | None | 1.18A | 6brdB-3p5mA:undetectable | 6brdB-3p5mA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sft | CHEMOTAXIS RESPONSEREGULATORPROTEIN-GLUTAMATEMETHYLESTERASE (Thermotogamaritima) |
PF01339(CheB_methylest) | 5 | GLY A 290VAL A 321THR A 303GLY A 302GLY A 301 | None | 0.96A | 6brdB-3sftA:undetectable | 6brdB-3sftA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sze | SERINE PROTEASE ESPP (Escherichiacoli) |
PF02395(Peptidase_S6) | 5 | GLY A 668VAL A 648THR A 705GLY A 706GLY A 707 | None | 1.20A | 6brdB-3szeA:undetectable | 6brdB-3szeA:6.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uma | HYPOTHETICALPEROXIREDOXINPROTEIN (Sinorhizobiummeliloti) |
PF08534(Redoxin) | 5 | GLY A 43VAL A 41PHE A 39GLY A 91GLY A 92 | None | 1.08A | 6brdB-3umaA:undetectable | 6brdB-3umaA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vta | CUCUMISIN (Cucumis melo) |
PF00082(Peptidase_S8) | 5 | ARG A 332GLY A 226THR A 211GLY A 232GLY A 214 | None | 1.21A | 6brdB-3vtaA:undetectable | 6brdB-3vtaA:13.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ain | GLYCINE BETAINETRANSPORTER BETP (Corynebacteriumglutamicum) |
PF02028(BCCT) | 6 | GLY A 201VAL A 200PHE A 529THR A 246GLY A 249MET A 479 | None | 1.35A | 6brdB-4ainA:undetectable | 6brdB-4ainA:10.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bed | HEMOCYANIN KLH1 (Megathuracrenulata) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 5 | GLY B2947PHE B3144GLY B2938GLY B2937MET B3103 | None | 1.15A | 6brdB-4bedB:undetectable | 6brdB-4bedB:4.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bhl | ARGININE KINASE (Litopenaeusvannamei) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 5 | VAL A 250PHE A 104THR A 277GLY A 276GLY A 266 | None | 0.99A | 6brdB-4bhlA:1.0 | 6brdB-4bhlA:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ccy | CARBOXYLESTERASEYBFK (Bacillussubtilis) |
PF12697(Abhydrolase_6) | 5 | HIS B 62GLY B 220PHE B 162GLY B 64GLY B 63 | None | 1.17A | 6brdB-4ccyB:undetectable | 6brdB-4ccyB:14.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d4p | PROTEIN ATS1,DIPHTHAMIDEBIOSYNTHESIS PROTEIN3 (Saccharomycescerevisiae) |
PF00415(RCC1)PF05207(zf-CSL) | 5 | GLY A 59VAL A 83PHE A 118THR A 98GLY A 113 | None | 1.13A | 6brdB-4d4pA:undetectable | 6brdB-4d4pA:11.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e0t | CYCLIC DIPEPTIDEN-PRENYLTRANSFERASE (Aspergillusfumigatus) |
PF11991(Trp_DMAT) | 5 | GLY A 95VAL A 135THR A 108GLY A 111GLY A 110 | NoneNoneEDO A 603 (-4.6A)NoneNone | 1.08A | 6brdB-4e0tA:undetectable | 6brdB-4e0tA:12.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g4i | 4-O-METHYL-GLUCURONOYL METHYLESTERASE (Thermothelomycesthermophila) |
no annotation | 5 | GLY A 337MET A 320THR A 210GLY A 211GLY A 216 | None | 1.16A | 6brdB-4g4iA:undetectable | 6brdB-4g4iA:10.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hjl | NAPHTHALENE1,2-DIOXYGENASESUBUNIT ALPHA (Pseudomonas sp.C18) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 5 | HIS A 261GLY A 178PHE A 147THR A 308GLY A 311 | None | 1.11A | 6brdB-4hjlA:undetectable | 6brdB-4hjlA:11.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i3f | SERINE HYDROLASECCSP0084 (Cycloclasticussp. P1) |
PF12697(Abhydrolase_6) | 5 | GLY A 131VAL A 130THR A 201GLY A 200GLY A 199 | None | 1.22A | 6brdB-4i3fA:undetectable | 6brdB-4i3fA:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ip4 | MANDELATERACEMASE/MUCONATELACTONIZINGENZYME-LIKE PROTEIN (Ruegeria sp.TM1040) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | GLY A 69VAL A 72PHE A 87GLY A 328GLY A 327 | None | 1.12A | 6brdB-4ip4A:undetectable | 6brdB-4ip4A:12.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jrm | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Vibrio cholerae) |
no annotation | 5 | GLY D 10VAL D 8PHE D 411GLY D 167GLY D 348 | None | 1.21A | 6brdB-4jrmD:undetectable | 6brdB-4jrmD:11.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3j | HEPATOCYTE GROWTHFACTORHEPATOCYTE GROWTHFACTOR BETA CHAIN (Homo sapiens) |
PF00089(Trypsin)PF01403(Sema)PF01437(PSI) | 5 | HIS A 517GLY B 225MET B 227ARG B 218GLY A 618 | None | 1.08A | 6brdB-4k3jA:undetectable | 6brdB-4k3jA:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k5r | OXYGENASE (Streptomycesargillaceus) |
PF01494(FAD_binding_3) | 5 | HIS A 57ARG A 225PHE A 272GLY A 302MET A 357 | NoneNoneFAD A 601 ( 4.2A)FAD A 601 (-3.4A)None | 0.99A | 6brdB-4k5rA:53.0 | 6brdB-4k5rA:12.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k5r | OXYGENASE (Streptomycesargillaceus) |
PF01494(FAD_binding_3) | 5 | HIS A 57ARG A 225VAL A 214GLY A 302MET A 357 | NoneNoneNoneFAD A 601 (-3.4A)None | 0.97A | 6brdB-4k5rA:53.0 | 6brdB-4k5rA:12.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k5r | OXYGENASE (Streptomycesargillaceus) |
PF01494(FAD_binding_3) | 5 | HIS A 57VAL A 214GLY A 301GLY A 302MET A 357 | NoneNoneNoneFAD A 601 (-3.4A)None | 0.64A | 6brdB-4k5rA:53.0 | 6brdB-4k5rA:12.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k5r | OXYGENASE (Streptomycesargillaceus) |
PF01494(FAD_binding_3) | 6 | HIS A 57VAL A 227PHE A 272GLY A 301GLY A 302MET A 357 | NoneNoneFAD A 601 ( 4.2A)NoneFAD A 601 (-3.4A)None | 0.80A | 6brdB-4k5rA:53.0 | 6brdB-4k5rA:12.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1k | D-ALANINE--D-ALANINELIGASE (Xanthomonasoryzae) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 5 | HIS A 17GLY A 75VAL A 76GLY A 12GLY A 11 | None | 1.08A | 6brdB-4l1kA:undetectable | 6brdB-4l1kA:11.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mst | CLASS I CHITINASE (Heveabrasiliensis) |
PF00182(Glyco_hydro_19) | 5 | GLY A 240VAL A 243PHE A 292THR A 229GLY A 230 | None | 0.92A | 6brdB-4mstA:undetectable | 6brdB-4mstA:15.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nen | INTEGRIN ALPHA-XINTEGRIN BETA-2 (Homo sapiens) |
PF00092(VWA)PF00362(Integrin_beta)PF01839(FG-GAP)PF07965(Integrin_B_tail)PF08441(Integrin_alpha2)PF17205(PSI_integrin) | 5 | GLY B 283VAL B 282PHE B 245THR A 411GLY A 412 | None | 1.01A | 6brdB-4nenB:undetectable | 6brdB-4nenB:8.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o89 | RNA 3'-TERMINALPHOSPHATE CYCLASE (Pyrococcushorikoshii) |
PF01137(RTC)PF05189(RTC_insert) | 5 | GLY A 166ARG A 116THR A 121GLY A 120GLY A 119 | None | 1.11A | 6brdB-4o89A:undetectable | 6brdB-4o89A:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oe7 | PROBABLE2-KETO-3-DEOXY-GALACTONATE ALDOLASE YAGE (Escherichiacoli) |
PF00701(DHDPS) | 5 | GLY A 240VAL A 242PHE A 208GLY A 214GLY A 215 | None | 1.15A | 6brdB-4oe7A:undetectable | 6brdB-4oe7A:15.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ppz | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Neisseriameningitidis) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | GLY A 67VAL A 162THR A 326GLY A 325GLY A 324 | NoneNoneNonePO4 A 603 ( 3.7A)None | 1.20A | 6brdB-4ppzA:2.7 | 6brdB-4ppzA:13.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ppz | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Neisseriameningitidis) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | GLY A 163VAL A 162THR A 326GLY A 325GLY A 324 | NoneNoneNonePO4 A 603 ( 3.7A)None | 1.06A | 6brdB-4ppzA:2.7 | 6brdB-4ppzA:13.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qtf | L,D-TRANSPEPTIDASELDTB (Mycobacteriumtuberculosis) |
PF03734(YkuD) | 5 | GLY A 332VAL A 333THR A 384GLY A 383GLY A 382 | 3V5 A 502 (-3.3A)3V5 A 502 ( 4.9A)NoneNoneNone | 1.22A | 6brdB-4qtfA:undetectable | 6brdB-4qtfA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4txg | CHITINASE (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18)PF06483(ChiC) | 5 | PHE A 330GLY A 289THR A 258GLY A 259GLY A 260 | None | 0.93A | 6brdB-4txgA:undetectable | 6brdB-4txgA:7.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uar | PROTEIN CBBY (Rhodobactersphaeroides) |
PF13419(HAD_2) | 5 | HIS A 75GLY A 11THR A 49GLY A 50GLY A 51 | NoneNoneNoneGOL A 301 (-3.4A)GOL A 301 ( 4.7A) | 1.10A | 6brdB-4uarA:undetectable | 6brdB-4uarA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wd1 | ACETOACETATE-COALIGASE (Streptomyceslividans) |
PF00501(AMP-binding)PF13193(AMP-binding_C)PF16177(ACAS_N) | 5 | HIS A 265ARG A 227THR A 166GLY A 171GLY A 170 | None | 1.18A | 6brdB-4wd1A:undetectable | 6brdB-4wd1A:10.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wia | PUTATIVEFLAGELLA-RELATEDPROTEIN H (Methanocaldococcusjannaschii) |
PF06745(ATPase) | 5 | ARG A 46PHE A 51GLY A 21GLY A 22MET A 182 | None | 1.12A | 6brdB-4wiaA:undetectable | 6brdB-4wiaA:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x33 | PROTEIN ATS1 (Saccharomycescerevisiae) |
PF00415(RCC1) | 5 | GLY B 59VAL B 83PHE B 118THR B 98GLY B 113 | None | 1.18A | 6brdB-4x33B:undetectable | 6brdB-4x33B:14.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xn3 | TAIL SPIKE PROTEIN (Salmonellavirus HK620) |
no annotation | 5 | GLY A 285VAL A 286THR A 297GLY A 298GLY A 265 | None | 1.20A | 6brdB-4xn3A:undetectable | 6brdB-4xn3A:8.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yly | PEPTIDYL-TRNAHYDROLASE (Staphylococcusaureus) |
PF01195(Pept_tRNA_hydro) | 5 | GLY A 6VAL A 88PHE A 126GLY A 110GLY A 109 | None | 1.14A | 6brdB-4ylyA:2.8 | 6brdB-4ylyA:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c0p | ENDO-ARABINASE (Bacteroidesthetaiotaomicron) |
PF04616(Glyco_hydro_43) | 5 | HIS A 302GLY A 217VAL A 216GLY A 284GLY A 285 | None | 1.13A | 6brdB-5c0pA:undetectable | 6brdB-5c0pA:13.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eeb | ALDEHYDEDEHYDROGENASE (Pyrobaculumferrireducens) |
PF00171(Aldedh) | 5 | GLY A 187VAL A 185THR A 93GLY A 98GLY A 97 | None | 1.13A | 6brdB-5eebA:undetectable | 6brdB-5eebA:9.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7u | CYCLOALTERNAN-FORMING ENZYME (Listeriamonocytogenes) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16338(DUF4968)PF16990(CBM_35) | 5 | PHE A 393GLY A 561VAL A 482THR A 423GLY A 394 | None | 1.22A | 6brdB-5f7uA:undetectable | 6brdB-5f7uA:6.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) |
PF00067(p450) | 5 | GLY A 156ARG A 161VAL A 157GLY A 190GLY A 191 | NoneNoneNone2OH A 402 ( 4.6A)None | 1.12A | 6brdB-5it1A:undetectable | 6brdB-5it1A:13.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j47 | LARGE T ANTIGEN (Humanpolyomavirus 2) |
PF06431(Polyoma_lg_T_C) | 5 | PHE A 377ARG A 596PHE A 315GLY A 378GLY A 381 | None | 1.06A | 6brdB-5j47A:undetectable | 6brdB-5j47A:11.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lhk | LEUCINEAMINOPEPTIDASE 2,CHLOROPLASTIC (Streptomycessp. BC16019) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 5 | GLY A 134ARG A 102THR A 482GLY A 481GLY A 480 | None | 1.10A | 6brdB-5lhkA:undetectable | 6brdB-5lhkA:10.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 5 | HIS A 381PHE A 400THR A 387GLY A 388GLY A 389 | ZN A 511 ( 3.3A) ZN A 511 ( 4.7A)NoneNone0TR A 513 (-3.8A) | 0.95A | 6brdB-5m8tA:undetectable | 6brdB-5m8tA:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mrw | POTASSIUM-TRANSPORTING ATPASE KDPCSUBUNIT (Escherichiacoli) |
PF02669(KdpC) | 5 | GLY C 67ARG C 101THR C 72GLY C 83GLY C 84 | None | 1.16A | 6brdB-5mrwC:undetectable | 6brdB-5mrwC:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nqa | POLYPEPTIDEN-ACETYLGALACTOSAMINYLTRANSFERASE 4 (Homo sapiens) |
no annotation | 5 | HIS A 287GLY A 350VAL A 345GLY A 276GLY A 277 | NoneNoneNoneNoneEDO A 603 (-4.7A) | 0.89A | 6brdB-5nqaA:undetectable | 6brdB-5nqaA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nvm | EUKARYOTICTRANSLATIONINITIATION FACTOR 4ETYPE 2 (Homo sapiens) |
PF01652(IF4E) | 5 | HIS A 217VAL A 162THR A 186GLY A 132GLY A 133 | None | 1.20A | 6brdB-5nvmA:2.1 | 6brdB-5nvmA:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u8e | ARGININE KINASE (Polybetespythagoricus) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 5 | VAL A 250PHE A 104THR A 277GLY A 276GLY A 266 | None | 0.93A | 6brdB-5u8eA:1.0 | 6brdB-5u8eA:11.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uan | RETINOIC ACIDRECEPTOR BETA (Homo sapiens) |
no annotation | 5 | PHE B 104GLY B 145VAL B 95GLY B 103GLY B 100 | None | 1.21A | 6brdB-5uanB:undetectable | 6brdB-5uanB:11.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vfd | BETA-LACTAMASE (Acinetobacterbaumannii) |
PF00905(Transpeptidase) | 5 | PHE A 182GLY A 230VAL A 229THR A 175GLY A 155 | None | 1.18A | 6brdB-5vfdA:undetectable | 6brdB-5vfdA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xi0 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Aliivibriofischeri) |
no annotation | 5 | GLY A 71VAL A 46THR A 60GLY A 64GLY A 65 | None | 0.95A | 6brdB-5xi0A:3.5 | 6brdB-5xi0A:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yb7 | L-AMINO ACIDOXIDASE/MONOOXYGENASE (Pseudomonas sp.AIU 813) |
no annotation | 5 | GLY A 263VAL A 261PHE A 110GLY A 80GLY A 81 | NoneNoneNoneNoneFAD A 601 (-3.0A) | 0.97A | 6brdB-5yb7A:10.4 | 6brdB-5yb7A:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zji | PHOTOSYSTEM IREACTION CENTERSUBUNIT VI,CHLOROPLASTICPHOTOSYSTEM IREACTION CENTERSUBUNIT XI (Zea mays) |
no annotation | 5 | PHE H 94GLY L 133THR L 183GLY L 184GLY L 185 | NoneBCR L 301 ( 4.7A)NoneNoneNone | 0.93A | 6brdB-5zjiH:undetectable | 6brdB-5zjiH:17.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6aun | PLA2G6, IPLA2BETA (Cricetulusgriseus) |
no annotation | 6 | GLY A 485VAL A 486PHE A 509THR A 466GLY A 467GLY A 468 | None | 1.41A | 6brdB-6aunA:undetectable | 6brdB-6aunA:20.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6c7s | PUTATIVE RIFAMPINMONOOXYGENASE (Nocardiafarcinica) |
no annotation | 5 | HIS A 46ARG A 351THR A 284GLY A 285GLY A 286 | NoneNoneRFH A 502 (-4.0A)RFH A 502 (-3.4A)FAD A 501 ( 3.3A) | 1.16A | 6brdB-6c7sA:63.3 | 6brdB-6c7sA:74.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6c7s | PUTATIVE RIFAMPINMONOOXYGENASE (Nocardiafarcinica) |
no annotation | 8 | HIS A 46PHE A 74ARG A 196GLY A 203PHE A 256THR A 284GLY A 285GLY A 286 | NoneRFH A 502 (-3.4A)RFH A 502 (-3.1A)RFH A 502 (-3.6A)RFH A 502 (-4.4A)RFH A 502 (-4.0A)RFH A 502 (-3.4A)FAD A 501 ( 3.3A) | 0.50A | 6brdB-6c7sA:63.3 | 6brdB-6c7sA:74.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6c7s | PUTATIVE RIFAMPINMONOOXYGENASE (Nocardiafarcinica) |
no annotation | 7 | HIS A 46PHE A 74ARG A 196GLY A 203PHE A 256THR A 284GLY A 286 | NoneRFH A 502 (-3.4A)RFH A 502 (-3.1A)RFH A 502 (-3.6A)RFH A 502 (-4.4A)RFH A 502 (-4.0A)FAD A 501 ( 3.3A) | 1.17A | 6brdB-6c7sA:63.3 | 6brdB-6c7sA:74.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d0n | CLC-TYPEFLUORIDE/PROTONANTIPORTER (Enterococcuscasseliflavus) |
no annotation | 5 | HIS A 109GLY A 153PHE A 353GLY A 116MET A 79 | None | 1.20A | 6brdB-6d0nA:undetectable | 6brdB-6d0nA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5d | ATP SYNTHASE SUBUNITBETA (Trypanosomabrucei) |
no annotation | 5 | VAL D 81PHE D 28THR D 37GLY D 86GLY D 85 | None | 1.18A | 6brdB-6f5dD:undetectable | 6brdB-6f5dD:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g2j | NADH DEHYDROGENASE[UBIQUINONE]FLAVOPROTEIN 1,MITOCHONDRIAL (Mus musculus) |
no annotation | 5 | PHE F 242GLY F 121VAL F 124GLY F 239GLY F 238 | None | 1.18A | 6brdB-6g2jF:undetectable | 6brdB-6g2jF:26.14 |