SIMILAR PATTERNS OF AMINO ACIDS FOR 6B68_D_9F2D400_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)

Filter list by:

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1alq	CP254 BETA-LACTAMASE (Staphylococcus aureus)	PF13354 (Beta-lactamase2)	5	SER A 70 SER A 130 ASN A 170 LYS A 234 GLY A 236	None	0.42A	6b68D-1alqA: 27.8	6b68D-1alqA: 15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1bsg	BETA LACTAMASE (Streptomyces albus)	PF13354 (Beta-lactamase2)	8	SER A 70 SER A 130 ASN A 170 THR A 216 ARG A 220 LYS A 234 GLY A 236 GLY A 238	None	0.58A	6b68D-1bsgA: 41.7	6b68D-1bsgA: 18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1bue	PROTEIN (IMIPENEM-HYDROLYSIN G BETA-LACTAMASE) (Enterobacter cloacae)	PF13354 (Beta-lactamase2)	7	SER A 70 SER A 130 ASN A 170 THR A 216 ARG A 220 LYS A 234 GLY A 236	None	0.37A	6b68D-1bueA: 38.5	6b68D-1bueA: 16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1dy6	CARBAPENEM-HYDROLYSI NG BETA-LACTAMASE SME-1 (Serratia marcescens)	PF13354 (Beta-lactamase2)	6	SER A 70 SER A 130 ASN A 170 THR A 216 ARG A 220 GLY A 239	None	0.89A	6b68D-1dy6A: 38.9	6b68D-1dy6A: 16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1dy6	CARBAPENEM-HYDROLYSI NG BETA-LACTAMASE SME-1 (Serratia marcescens)	PF13354 (Beta-lactamase2)	7	SER A 70 SER A 130 ASN A 170 THR A 216 ARG A 220 LYS A 234 GLY A 236	None	0.42A	6b68D-1dy6A: 38.9	6b68D-1dy6A: 16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1e25	EXTENDED-SPECTRUM BETA-LACTAMASE PER-1 (Pseudomonas aeruginosa)	PF13354 (Beta-lactamase2)	8	SER A 70 SER A 130 THR A 216 ARG A 220 LYS A 234 GLY A 236 THR A 237 GLU A 276	SO4 A 500 (-3.1A) SO4 A 500 (-2.6A) SO4 A 500 ( 4.0A) SO4 A 500 ( 4.2A) SO4 A 500 (-3.2A) SO4 A 500 (-3.5A) SO4 A 500 (-3.5A) None	0.45A	6b68D-1e25A: 31.4	6b68D-1e25A: 11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1g68	BETA-LACTAMASE PSE-4 (Pseudomonas aeruginosa)	PF13354 (Beta-lactamase2)	5	SER A 70 SER A 130 ASN A 170 GLY A 236 GLY A 238	SO4 A 400 (-2.9A) SO4 A 400 (-2.7A) None SO4 A 400 (-3.0A) None	0.62A	6b68D-1g68A: 37.1	6b68D-1g68A: 15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1hzo	BETA-LACTAMASE (Proteus vulgaris)	PF13354 (Beta-lactamase2)	8	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 236 GLY A 238 ASP A 240	MES A1000 (-3.1A) MES A1000 (-2.7A) None MES A1000 (-3.7A) MES A1000 (-2.9A) MES A1000 (-3.1A) None None	0.51A	6b68D-1hzoA: 41.3	6b68D-1hzoA: 22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1i2w	BETA-LACTAMASE (Bacillus licheniformis)	PF13354 (Beta-lactamase2)	6	SER A 70 SER A 130 THR A 216 LYS A 234 GLY A 236 GLY A 238	CFX A1300 (-1.3A) CFX A1300 (-3.1A) CFX A1300 (-3.2A) CFX A1300 ( 3.9A) CFX A1300 (-3.3A) CFX A1300 ( 4.1A)	0.42A	6b68D-1i2wA: 41.8	6b68D-1i2wA: 17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1j9m	DD-TRANSPEPTIDASE (Streptomyces sp. K15)	PF00768 (Peptidase_S11)	6	SER A 35 SER A 96 THR A 199 ARG A 248 LYS A 213 GLY A 215	NA A 600 (-3.3A) NA A 600 (-3.1A) NA A 600 ( 4.5A) CL A 601 (-3.1A) NA A 600 (-3.4A) NA A 600 ( 3.6A)	0.89A	6b68D-1j9mA: 22.5	6b68D-1j9mA: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1j9m	DD-TRANSPEPTIDASE (Streptomyces sp. K15)	PF00768 (Peptidase_S11)	6	SER A 96 THR A 199 ARG A 248 LYS A 213 GLY A 215 GLY A 217	NA A 600 (-3.1A) NA A 600 ( 4.5A) CL A 601 (-3.1A) NA A 600 (-3.4A) NA A 600 ( 3.6A) None	0.67A	6b68D-1j9mA: 22.5	6b68D-1j9mA: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1n4o	L2 BETA-LACTAMASE (Stenotrophomonas maltophilia)	PF13354 (Beta-lactamase2)	6	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 236	SO4 A1002 (-2.9A) SO4 A1002 (-3.1A) None SO4 A1002 ( 4.8A) SO4 A1002 (-3.6A) SO4 A1002 (-3.2A)	0.32A	6b68D-1n4oA: 37.6	6b68D-1n4oA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1n9b	BETA-LACTAMASE SHV-2 (Klebsiella pneumoniae)	PF13354 (Beta-lactamase2)	5	SER A 70 SER A 130 ASN A 170 LYS A 234 GLY A 236	EPE A 400 (-3.7A) EPE A 400 (-2.5A) None EPE A 400 (-3.1A) EPE A 400 (-3.1A)	0.69A	6b68D-1n9bA: 34.1	6b68D-1n9bA: 17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1nrf	REGULATORY PROTEIN BLAR1 (Bacillus licheniformis)	PF00905 (Transpeptidase)	5	SER A 402 SER A 450 LYS A 539 GLY A 541 THR A 542	None	0.49A	6b68D-1nrfA: 18.9	6b68D-1nrfA: 14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1w5d	PENICILLIN-BINDING PROTEIN (Bacillus subtilis)	PF02113 (Peptidase_S13)	5	SER A 52 SER A 299 THR A 394 LYS A 411 GLY A 413	None	0.35A	6b68D-1w5dA: 20.2	6b68D-1w5dA: 11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1xp4	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE (Streptococcus pneumoniae)	PF00768 (Peptidase_S11) PF07943 (PBP5_C)	8	SER A 56 SER A 119 THR A 221 ARG A 278 LYS A 239 GLY A 241 THR A 242 ASP A 244	SO4 A 464 (-3.4A) SO4 A 464 (-3.4A) SO4 A 464 ( 4.0A) SO4 A 464 ( 4.1A) SO4 A 464 (-3.5A) SO4 A 464 ( 3.8A) SO4 A 464 (-4.0A) None	0.62A	6b68D-1xp4A: 20.5	6b68D-1xp4A: 13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1zg4	BETA-LACTAMASE TEM (Escherichia coli)	PF13354 (Beta-lactamase2)	6	SER A 70 SER A 130 ASN A 170 LYS A 234 GLY A 236 GLY A 238	None	0.32A	6b68D-1zg4A: 36.7	6b68D-1zg4A: 14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	PF00905 (Transpeptidase)	5	SER B 370 SER B 428 THR B 543 LYS B 557 GLY B 559	CL B 704 (-3.5A) CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 ( 4.0A)	0.68A	6b68D-2c6wB: 16.5	6b68D-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2c6w	PENICILLIN-BINDING PROTEIN 1A (Streptococcus pneumoniae)	PF00905 (Transpeptidase)	5	SER B 428 THR B 543 LYS B 557 GLY B 559 THR B 560	CL B 704 (-3.4A) CL B 704 ( 4.8A) None CL B 704 ( 4.0A) CL B 704 ( 4.8A)	0.69A	6b68D-2c6wB: 16.5	6b68D-2c6wB: 12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2cc1	BETA-LACTAMASE (Mycolicibacterium fortuitum)	PF13354 (Beta-lactamase2)	8	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 236 GLY A 238 ASP A 240	None	0.36A	6b68D-2cc1A: 39.4	6b68D-2cc1A: 16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2fff	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	PF00905 (Transpeptidase)	6	SER B 460 SER B 516 THR B 629 LYS B 651 GLY B 653 THR B 654	None	0.54A	6b68D-2fffB: 16.3	6b68D-2fffB: 9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2iwb	METHICILLIN RESISTANCE MECR1 PROTEIN (Staphylococcus aureus)	PF00905 (Transpeptidase)	6	SER A 391 SER A 439 LYS A 528 GLY A 530 THR A 531 GLY A 532	GOL A 604 ( 2.7A) GOL A 604 (-2.6A) GOL A 604 (-2.9A) GOL A 605 ( 3.2A) GOL A 604 ( 3.6A) None	0.38A	6b68D-2iwbA: 18.9	6b68D-2iwbA: 17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2jch	PENICILLIN-BINDING PROTEIN 1B (Streptococcus pneumoniae)	PF00905 (Transpeptidase) PF00912 (Transgly)	6	SER A 460 SER A 516 THR A 629 LYS A 651 GLY A 653 THR A 654	PL7 A1793 (-1.4A) PL7 A1793 (-3.0A) PL7 A1793 ( 4.1A) PL7 A1793 ( 4.1A) PL7 A1793 (-3.3A) PL7 A1793 (-4.1A)	0.56A	6b68D-2jchA: 15.3	6b68D-2jchA: 8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2v2f	PENICILLIN BINDING PROTEIN 1A (Streptococcus pneumoniae)	PF00905 (Transpeptidase)	5	SER F 428 THR F 543 LYS F 557 GLY F 559 THR F 560	MES F1653 (-3.1A) MES F1653 (-3.7A) MES F1653 ( 4.0A) MES F1653 (-3.6A) MES F1653 (-3.6A)	0.64A	6b68D-2v2fF: 17.5	6b68D-2v2fF: 12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2wae	PENICILLIN-BINDING PROTEIN 2B (Streptococcus pneumoniae)	PF00905 (Transpeptidase) PF03717 (PBP_dimer)	5	SER A 386 SER A 443 THR A 600 LYS A 615 GLY A 617	None	0.50A	6b68D-2waeA: 15.6	6b68D-2waeA: 8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	PF13354 (Beta-lactamase2)	7	SER A 47 SER A 109 ARG A 239 LYS A 254 GLY A 256 THR A 257 GLU A 295	None	0.57A	6b68D-2wuqA: 29.0	6b68D-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	PF13354 (Beta-lactamase2)	8	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 236 GLY A 238 ASP A 240	None	0.52A	6b68D-2wyxA: 40.6	6b68D-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2z2m	PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	PF00905 (Transpeptidase)	6	SER B 337 SER B 395 THR B 526 LYS B 547 GLY B 549 THR B 550	CDS B 901 ( 1.3A) CDS B 901 ( 3.2A) CDS B 901 ( 4.1A) CDS B 901 ( 3.9A) CDS B 901 ( 3.4A) CDS B 901 ( 3.6A)	0.40A	6b68D-2z2mB: 16.1	6b68D-2z2mB: 13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3a3i	PENICILLIN-BINDING PROTEIN 4 (Haemophilus influenzae)	PF02113 (Peptidase_S13)	5	SER A 69 SER A 310 THR A 401 LYS A 420 GLY A 422	AIX A 501 (-1.3A) AIX A 501 (-2.8A) AIX A 501 ( 4.0A) AIX A 501 ( 3.8A) AIX A 501 (-3.4A)	0.37A	6b68D-3a3iA: 20.1	6b68D-3a3iA: 12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3bfg	CLASS A BETA-LACTAMASE SED1 (Citrobacter sedlakii)	PF13354 (Beta-lactamase2)	7	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 236 ASP A 240	MER A 301 (-1.3A) MER A 301 (-2.6A) MER A 301 (-2.6A) MER A 301 (-3.6A) MER A 301 (-3.2A) MER A 301 (-3.0A) None	0.64A	6b68D-3bfgA: 41.0	6b68D-3bfgA: 18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3byd	BETA-LACTAMASE OXY-1 (Klebsiella oxytoca)	PF13354 (Beta-lactamase2)	8	SER A 73 SER A 133 ASN A 173 THR A 219 LYS A 237 GLY A 239 GLY A 241 ASP A 242	SO4 A 301 (-2.9A) SO4 A 301 (-2.8A) None SO4 A 301 ( 4.0A) SO4 A 301 (-3.1A) SO4 A 301 (-3.3A) None None	0.45A	6b68D-3bydA: 41.5	6b68D-3bydA: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3cjm	PUTATIVE BETA-LACTAMASE (Enterococcus faecalis)	PF13354 (Beta-lactamase2)	6	SER A 108 SER A 169 ARG A 244 LYS A 257 GLY A 259 ASP A 262	NO3 A 1 (-2.9A) None EDO A 6 ( 4.5A) None None None	0.59A	6b68D-3cjmA: 26.0	6b68D-3cjmA: 13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3dwk	PENICILLIN-BINDING PROTEIN 2 (Staphylococcus aureus)	PF00905 (Transpeptidase) PF00912 (Transgly)	5	SER A 454 LYS A 583 GLY A 585 THR A 586 GLY A 587	SO4 A 26 (-3.1A) SO4 A 26 ( 4.2A) SO4 A 26 (-3.3A) SO4 A 26 (-3.5A) None	0.53A	6b68D-3dwkA: 17.8	6b68D-3dwkA: 8.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3dwz	BETA-LACTAMASE (Mycobacterium tuberculosis)	PF13354 (Beta-lactamase2)	11	SER A 84 SER A 142 ASN A 186 THR A 232 ARG A 236 LYS A 250 GLY A 252 THR A 253 GLY A 254 ASP A 255 GLU A 292	DWZ A 400 (-1.3A) DWZ A 400 (-2.7A) DWZ A 400 ( 4.0A) DWZ A 400 ( 4.5A) DWZ A 400 ( 4.3A) DWZ A 400 ( 3.8A) DWZ A 400 (-3.3A) DWZ A 400 (-4.1A) None None None	0.33A	6b68D-3dwzA: 48.5	6b68D-3dwzA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3hum	PENICILLIN-BINDING PROTEIN 4 (Staphylococcus aureus)	PF00768 (Peptidase_S11) PF09211 (DUF1958)	6	SER A 75 SER A 139 LYS A 259 GLY A 261 ASP A 264 GLU A 297	CEW A 501 (-2.6A) CEW A 501 (-3.4A) CEW A 501 ( 4.4A) CEW A 501 (-3.1A) None CEW A 501 (-3.2A)	0.72A	6b68D-3humA: 22.5	6b68D-3humA: 11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3lez	BETA-LACTAMASE (Oceanobacillus iheyensis)	PF13354 (Beta-lactamase2)	6	SER A 85 ASN A 183 THR A 229 LYS A 247 GLY A 249 GLY A 251	EPE A 305 (-3.4A) None EPE A 305 ( 3.9A) EPE A 305 (-3.1A) EPE A 305 (-3.4A) None	0.41A	6b68D-3lezA: 40.7	6b68D-3lezA: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3p09	BETA-LACTAMASE (Francisella tularensis)	PF13354 (Beta-lactamase2)	9	SER A 61 SER A 122 ASN A 162 THR A 208 ARG A 212 LYS A 226 GLY A 228 THR A 229 GLU A 268	SO4 A 288 (-3.1A) SO4 A 288 (-2.7A) None SO4 A 288 ( 4.8A) SO4 A 288 ( 4.4A) SO4 A 288 (-3.5A) SO4 A 288 (-3.3A) SO4 A 288 (-3.4A) None	0.33A	6b68D-3p09A: 39.3	6b68D-3p09A: 25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3q7z	BETA-LACTAMASE REGULATORY PROTEIN BLAR1 (Staphylococcus aureus)	PF00905 (Transpeptidase)	6	SER A 389 SER A 437 LYS A 526 GLY A 528 THR A 529 GLY A 530	BOU A 584 (-1.4A) BOU A 584 (-2.8A) BOU A 584 (-3.3A) BOU A 584 (-3.7A) BOU A 584 (-3.6A) BOU A 584 ( 3.9A)	0.43A	6b68D-3q7zA: 17.7	6b68D-3q7zA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qhy	BETA-LACTAMASE (Bacillus anthracis)	PF13354 (Beta-lactamase2)	7	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 236 GLY A 238	None	0.34A	6b68D-3qhyA: 41.7	6b68D-3qhyA: 23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qnb	OXACILLINASE (Escherichia coli)	PF00905 (Transpeptidase)	6	SER A 67 SER A 115 ARG A 250 LYS A 205 GLY A 207 GLY A 209	KCX A 70 ( 2.7A) KCX A 70 ( 4.6A) SO4 A 4 (-3.4A) KCX A 70 ( 4.7A) None None	0.97A	6b68D-3qnbA: 18.7	6b68D-3qnbA: 14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ue1	PENICILLIN-BINDING PROTEIN 1A (Acinetobacter baumannii)	PF00905 (Transpeptidase) PF00912 (Transgly) PF17092 (PCB_OB)	5	SER A 434 SER A 487 LYS A 669 GLY A 671 THR A 672	UE1 A 998 (-1.7A) UE1 A 998 (-3.3A) UE1 A 998 ( 3.8A) UE1 A 998 (-3.4A) UE1 A 998 (-3.6A)	0.70A	6b68D-3ue1A: 14.7	6b68D-3ue1A: 7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3v39	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE (Bdellovibrio bacteriovorus)	PF02113 (Peptidase_S13)	5	SER A 70 SER A 251 THR A 342 LYS A 357 GLY A 359	TAU A 501 (-1.5A) TAU A 501 (-2.6A) None TAU A 501 ( 4.3A) TAU A 501 (-3.5A)	0.29A	6b68D-3v39A: 17.0	6b68D-3v39A: 11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3vsk	PENICILLIN-BINDING PROTEIN 3 (Staphylococcus aureus)	PF00905 (Transpeptidase) PF03717 (PBP_dimer)	5	SER A 392 SER A 448 THR A 603 LYS A 618 GLY A 620	None	0.50A	6b68D-3vskA: 17.0	6b68D-3vskA: 9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3w4q	BETA-LACTAMASE (Burkholderia multivorans)	PF13354 (Beta-lactamase2)	9	SER A 70 SER A 130 ASN A 170 ARG A 220 LYS A 234 GLY A 236 THR A 237 GLY A 238 ASP A 240	None	0.36A	6b68D-3w4qA: 41.2	6b68D-3w4qA: 17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3zdj	ENCA BETA-LACTAMASE (synthetic construct)	PF13354 (Beta-lactamase2)	6	SER A 70 SER A 130 ASN A 170 LYS A 234 GLY A 236 GLY A 238	SO4 A1291 (-3.4A) SO4 A1291 (-3.1A) None SO4 A1291 (-3.3A) SO4 A1291 (-3.3A) None	0.30A	6b68D-3zdjA: 36.8	6b68D-3zdjA: 15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3zg8	PENICILLIN-BINDING PROTEIN 4 (Listeria monocytogenes)	PF00905 (Transpeptidase) PF00912 (Transgly)	5	SER B 394 SER B 449 THR B 561 LYS B 575 GLY B 577	AIX B 800 (-0.2A) AIX B 800 (-2.4A) AIX B 800 ( 3.8A) AIX B 800 ( 4.0A) AIX B 800 ( 3.7A)	0.41A	6b68D-3zg8B: 16.4	6b68D-3zg8B: 9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3zny	CTX-M-12A ENZYME (Klebsiella pneumoniae)	PF13354 (Beta-lactamase2)	7	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 236 GLY A 238	None	0.47A	6b68D-3znyA: 41.5	6b68D-3znyA: 22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3zvt	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE (Actinomadura sp. R39)	PF02113 (Peptidase_S13)	5	SER A 49 SER A 298 THR A 393 LYS A 410 GLY A 412	B07 A 500 (-1.4A) B07 A 500 (-1.4A) B07 A 500 ( 4.8A) B07 A 500 (-1.6A) B07 A 500 (-3.2A)	0.63A	6b68D-3zvtA: 20.2	6b68D-3zvtA: 10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4c6y	BETA-LACTAMASE (synthetic construct)	PF13354 (Beta-lactamase2)	9	SER A 70 SER A 130 ASN A 170 THR A 216 ARG A 220 LYS A 234 GLY A 236 THR A 237 GLY A 238	PEG A 307 (-2.4A) PEG A 307 (-2.4A) PEG A 307 ( 4.3A) PEG A 307 ( 4.3A) PEG A 307 ( 3.6A) PEG A 307 ( 3.4A) PEG A 307 (-2.7A) PEG A 307 (-3.9A) None	0.31A	6b68D-4c6yA: 40.4	6b68D-4c6yA: 25.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4c75	BETA-LACTAMASE (synthetic construct)	PF13354 (Beta-lactamase2)	8	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 236 THR A 237 GLY A 238	NA A 294 ( 2.5A) SO4 A 291 (-2.8A) None SO4 A 291 ( 4.1A) SO4 A 291 (-3.4A) NA A 294 ( 3.2A) SO4 A 291 ( 3.4A) None	0.42A	6b68D-4c75A: 40.3	6b68D-4c75A: 24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4d2o	PER-2 BETA-LACTAMASE (Citrobacter freundii)	PF13354 (Beta-lactamase2)	7	ARG A 240 THR A 216 ARG A 220 LYS A 234 GLY A 236 THR A 237 GLU A 276	None	1.14A	6b68D-4d2oA: 31.1	6b68D-4d2oA: 13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4d2o	PER-2 BETA-LACTAMASE (Citrobacter freundii)	PF13354 (Beta-lactamase2)	8	SER A 70 SER A 130 THR A 216 ARG A 220 LYS A 234 GLY A 236 THR A 237 GLU A 276	None	0.57A	6b68D-4d2oA: 31.1	6b68D-4d2oA: 13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ev4	CARBAPENEM-HYDROLIZI NG BETA-LACTAMASE SFC-1 (Serratia fonticola)	PF13354 (Beta-lactamase2)	8	SER A 70 SER A 130 ASN A 170 THR A 216 ARG A 220 LYS A 234 GLY A 236 THR A 237	MER A 401 (-1.3A) MER A 401 (-2.8A) MER A 401 (-2.9A) MER A 401 ( 3.9A) MER A 401 ( 3.9A) MER A 401 (-3.0A) MER A 401 (-3.6A) MER A 401 (-3.7A)	0.42A	6b68D-4ev4A: 39.5	6b68D-4ev4A: 18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ewf	BETA-LACTAMASE (Sphaerobacter thermophilus)	PF13354 (Beta-lactamase2)	6	SER A 49 SER A 110 ARG A 197 LYS A 213 GLY A 215 GLU A 250	SO4 A 301 (-3.1A) SO4 A 301 (-3.1A) SO4 A 301 ( 3.7A) SO4 A 301 (-3.0A) SO4 A 301 (-3.5A) None	0.33A	6b68D-4ewfA: 30.8	6b68D-4ewfA: 15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4fsf	PENICILLIN-BINDING PROTEIN 3 (Pseudomonas aeruginosa)	PF00905 (Transpeptidase) PF03717 (PBP_dimer)	5	SER A 294 SER A 349 LYS A 484 GLY A 486 THR A 487	0W0 A 601 (-1.4A) 0W0 A 601 (-3.1A) 0W0 A 601 (-3.0A) 0W0 A 601 (-3.4A) 0W0 A 601 (-3.7A)	0.38A	6b68D-4fsfA: 17.0	6b68D-4fsfA: 12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4gn2	OXACILLINASE (Pseudomonas aeruginosa)	PF00905 (Transpeptidase)	6	SER A 63 SER A 112 LYS A 208 GLY A 210 THR A 211 GLY A 212	KCX A 66 ( 2.9A) KCX A 66 ( 3.5A) KCX A 66 ( 4.5A) None None None	0.35A	6b68D-4gn2A: 17.3	6b68D-4gn2A: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ied	CLASS D BETA-LACTAMASE (Fusobacterium nucleatum)	PF00905 (Transpeptidase)	6	SER A 57 SER A 106 ARG A 239 LYS A 196 GLY A 198 ASP A 202	KCX A 60 ( 2.7A) KCX A 60 ( 3.4A) None KCX A 60 ( 4.5A) None None	1.12A	6b68D-4iedA: 19.2	6b68D-4iedA: 15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4k0x	BETA-LACTAMASE (Acinetobacter baumannii)	PF00905 (Transpeptidase)	6	SER A 79 SER A 126 ARG A 259 LYS A 216 GLY A 218 ASP A 222	KCX A 82 (-2.5A) BCT A 301 (-2.8A) BCT A 301 (-3.0A) BCT A 301 (-3.0A) BCT A 301 (-3.4A) None	0.89A	6b68D-4k0xA: 19.3	6b68D-4k0xA: 16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4mnr	PEPTIDOGLYCAN GLYCOSYLTRANSFERASE (Eggerthella lenta)	PF00905 (Transpeptidase)	5	SER A 237 THR A 383 LYS A 397 GLY A 399 THR A 400	None	0.61A	6b68D-4mnrA: 16.7	6b68D-4mnrA: 13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4oh0	BETA-LACTAMASE OXA-58 (Acinetobacter baumannii)	PF00905 (Transpeptidase)	5	SER A 83 SER A 130 LYS A 220 GLY A 222 GLY A 224	KCX A 86 ( 2.6A) KCX A 86 ( 3.3A) CL A 301 ( 4.4A) CL A 301 (-3.6A) None	0.58A	6b68D-4oh0A: 17.8	6b68D-4oh0A: 12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4oon	PENICILLIN-BINDING PROTEIN 1A (Pseudomonas aeruginosa)	PF00905 (Transpeptidase) PF00912 (Transgly) PF17092 (PCB_OB)	6	SER A 461 SER A 520 THR A 680 LYS A 695 GLY A 697 THR A 698	2U4 A 901 (-1.3A) 2U4 A 901 (-3.6A) 2U4 A 901 (-4.1A) 2U4 A 901 ( 4.3A) 2U4 A 901 (-3.7A) 2U4 A 901 (-3.8A)	0.70A	6b68D-4oonA: 16.1	6b68D-4oonA: 7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ovd	PEPTIDOGLYCAN GLYCOSYLTRANSFERASE (Atopobium parvulum)	PF00905 (Transpeptidase) PF03717 (PBP_dimer)	6	SER A 361 THR A 486 LYS A 500 GLY A 502 THR A 503 GLY A 504	CA A 601 ( 3.8A) CA A 601 ( 4.7A) CA A 601 ( 4.1A) CA A 601 ( 4.2A) None None	1.11A	6b68D-4ovdA: 17.0	6b68D-4ovdA: 9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ra7	PEPTIDOGLYCAN GLYCOSYLTRANSFERASE (Atopobium parvulum)	PF00905 (Transpeptidase)	7	SER A 682 SER A 737 THR A 876 LYS A 890 GLY A 892 THR A 893 ASP A 895	NXU A1001 (-1.3A) NXU A1001 (-3.2A) NXU A1001 (-4.0A) NXU A1001 (-3.5A) NXU A1001 (-3.4A) NXU A1001 (-3.9A) NXU A1001 (-3.1A)	0.58A	6b68D-4ra7A: 16.2	6b68D-4ra7A: 13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4yfm	BETA-LACTAMASE (Mycobacteroides abscessus)	PF13354 (Beta-lactamase2)	7	SER A 71 SER A 131 ASN A 171 THR A 215 LYS A 233 GLY A 235 GLY A 237	ACT A 301 (-3.5A) ACT A 301 (-2.9A) None ACT A 301 (-3.7A) ACT A 301 (-3.4A) ACT A 301 (-3.3A) None	0.34A	6b68D-4yfmA: 39.7	6b68D-4yfmA: 17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ztk	CELL DIVISION PROTEIN FTSI/PENICILLIN BINDING PROTEIN 2 (Legionella pneumophila)	PF00905 (Transpeptidase)	6	SER A 400 SER A 454 THR A 554 LYS A 568 GLY A 570 GLU A 617	NHE A 901 (-3.2A) NHE A 901 (-2.9A) NHE A 901 ( 4.2A) NHE A 901 (-3.0A) NHE A 901 (-3.6A) None	1.02A	6b68D-4ztkA: 16.1	6b68D-4ztkA: 11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ztk	CELL DIVISION PROTEIN FTSI/PENICILLIN BINDING PROTEIN 2 (Legionella pneumophila)	PF00905 (Transpeptidase)	6	SER A 400 SER A 454 THR A 554 LYS A 568 GLY A 570 THR A 571	NHE A 901 (-3.2A) NHE A 901 (-2.9A) NHE A 901 ( 4.2A) NHE A 901 (-3.0A) NHE A 901 (-3.6A) NHE A 901 (-3.8A)	0.49A	6b68D-4ztkA: 16.1	6b68D-4ztkA: 11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5aqa	OFF7_DB04V3 (synthetic construct)	PF00023 (Ank) PF12796 (Ank_2) PF13354 (Beta-lactamase2)	6	SER A 200 SER A 260 ASN A 300 LYS A 364 GLY A 366 GLY A 368	None	0.42A	6b68D-5aqaA: 35.8	6b68D-5aqaA: 11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5boh	BETA-LACTAMASE (Acinetobacter baumannii)	PF00905 (Transpeptidase)	6	SER A 83 SER A 130 ARG A 263 LYS A 220 GLY A 222 GLY A 224	KCX A 86 ( 2.7A) KCX A 86 ( 3.5A) None KCX A 86 ( 4.5A) None None	0.90A	6b68D-5bohA: 18.3	6b68D-5bohA: 12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5cer	BD0816 (Bdellovibrio bacteriovorus)	PF02113 (Peptidase_S13)	5	SER A 239 THR A 330 LYS A 345 GLY A 347 THR A 348	None	0.31A	6b68D-5cerA: 17.8	6b68D-5cerA: 11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ctm	BETA-LACTAMASE (Bacillus pumilus)	PF00905 (Transpeptidase)	5	SER A 101 SER A 149 LYS A 239 GLY A 241 GLY A 243	KCX A 104 (-2.2A) FLC A 301 (-2.5A) FLC A 301 (-3.0A) FLC A 301 (-3.2A) None	0.61A	6b68D-5ctmA: 17.4	6b68D-5ctmA: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5cxw	PENICILLIN-BINDING PROTEIN 1A (Mycobacterium tuberculosis)	PF00905 (Transpeptidase)	5	SER A 345 SER A 398 LYS A 539 GLY A 541 THR A 542	35P A 702 (-1.3A) 35P A 702 (-2.9A) 35P A 702 (-3.3A) 35P A 702 (-3.5A) 35P A 702 (-3.7A)	0.38A	6b68D-5cxwA: 17.1	6b68D-5cxwA: 13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5e2e	BETA-LACTAMASE (Yersinia enterocolitica)	PF13354 (Beta-lactamase2)	8	SER A 47 SER A 107 ASN A 147 THR A 193 ARG A 251 GLY A 213 GLY A 215 ASP A 216	None	0.95A	6b68D-5e2eA: 41.2	6b68D-5e2eA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5e2e	BETA-LACTAMASE (Yersinia enterocolitica)	PF13354 (Beta-lactamase2)	8	SER A 47 SER A 107 ASN A 147 THR A 193 LYS A 211 GLY A 213 GLY A 215 ASP A 216	None	0.48A	6b68D-5e2eA: 41.2	6b68D-5e2eA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5e2h	BETA-LACTAMASE (Mycolicibacterium smegmatis)	PF00144 (Beta-lactamase)	5	SER A 58 ARG A 341 LYS A 307 GLY A 309 ASP A 312	None	0.66A	6b68D-5e2hA: 15.2	6b68D-5e2hA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5e43	BETA-LACTAMASE (Streptosporangium roseum)	PF13354 (Beta-lactamase2)	8	SER A 70 SER A 131 ASN A 171 THR A 217 ARG A 221 LYS A 235 GLY A 237 THR A 238	ACT A 311 (-3.2A) ACT A 311 (-3.0A) None ACT A 311 ( 3.9A) ACT A 311 (-4.5A) ACT A 311 (-3.3A) ACT A 311 (-3.2A) ACT A 311 (-3.8A)	0.35A	6b68D-5e43A: 41.1	6b68D-5e43A: 15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5eoe	BETA-LACTAMASE (Pseudomonas aeruginosa)	PF13354 (Beta-lactamase2)	6	SER A 62 SER A 123 ASN A 163 THR A 209 LYS A 227 GLY A 229	CIT A 303 (-2.8A) CIT A 303 (-2.5A) None CIT A 303 (-3.2A) CIT A 303 (-3.5A) CIT A 303 (-3.5A)	0.38A	6b68D-5eoeA: 39.4	6b68D-5eoeA: 16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5f83	BETA-LACTAMASE (Pseudomonas aeruginosa)	PF13354 (Beta-lactamase2)	6	SER A 64 SER A 125 THR A 211 LYS A 229 GLY A 231 THR A 232	IM2 A 301 (-1.4A) IM2 A 301 (-2.7A) IM2 A 301 (-4.1A) IM2 A 301 (-3.3A) IM2 A 301 (-3.3A) IM2 A 301 (-4.0A)	0.40A	6b68D-5f83A: 38.3	6b68D-5f83A: 15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5gl9	BETA-LACTAMASE (Burkholderia thailandensis)	PF13354 (Beta-lactamase2)	10	SER A 70 SER A 130 ASN A 170 THR A 216 ARG A 220 LYS A 234 GLY A 236 THR A 237 GLY A 238 ASP A 240	None	0.37A	6b68D-5gl9A: 41.1	6b68D-5gl9A: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5hlb	PENICILLIN-BINDING PROTEIN 1B (Escherichia coli)	PF00905 (Transpeptidase) PF00912 (Transgly) PF14814 (UB2H)	6	SER A 510 SER A 572 THR A 682 LYS A 698 GLY A 700 THR A 701	AZR A 902 (-1.4A) AZR A 902 ( 3.7A) AZR A 902 (-3.4A) AZR A 902 ( 4.5A) AZR A 902 (-3.3A) AZR A 902 (-4.3A)	0.58A	6b68D-5hlbA: 17.6	6b68D-5hlbA: 8.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5hw3	BETA-LACTAMASE (Burkholderia vietnamiensis)	PF13354 (Beta-lactamase2)	6	SER A 70 ASN A 171 ARG A 219 GLY A 235 THR A 236 GLU A 273	SO4 A 301 (-2.7A) ACT A 310 (-4.0A) SO4 A 301 ( 4.2A) SO4 A 301 (-3.4A) SO4 A 301 (-3.5A) None	0.27A	6b68D-5hw3A: 38.4	6b68D-5hw3A: 40.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5hw3	BETA-LACTAMASE (Burkholderia vietnamiensis)	PF13354 (Beta-lactamase2)	6	SER A 70 SER A 131 ARG A 219 GLY A 235 THR A 236 GLU A 273	SO4 A 301 (-2.7A) SO4 A 301 (-2.6A) SO4 A 301 ( 4.2A) SO4 A 301 (-3.4A) SO4 A 301 (-3.5A) None	0.49A	6b68D-5hw3A: 38.4	6b68D-5hw3A: 40.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5hx9	BETA-LACTAMASE (Burkholderia vietnamiensis)	PF13354 (Beta-lactamase2)	5	ASN A 170 LYS A 234 GLY A 236 THR A 237 GLY A 238	None EDO A 303 (-2.6A) None None None	0.47A	6b68D-5hx9A: 38.7	6b68D-5hx9A: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ihv	BETA-LACTAMASE (Burkholderia ambifaria)	PF13354 (Beta-lactamase2)	5	ASN A 147 LYS A 211 GLY A 213 THR A 214 GLY A 215	None EDO A 302 (-2.8A) None None None	0.48A	6b68D-5ihvA: 39.0	6b68D-5ihvA: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5iy2	BETA-LACTAMASE OXA-143 (Acinetobacter baumannii)	PF00905 (Transpeptidase)	6	SER A 81 SER A 128 ARG A 261 LYS A 218 GLY A 220 ASP A 224	KCX A 84 (-2.7A) GOL A 301 (-3.6A) GOL A 301 (-3.1A) GOL A 301 ( 4.7A) GOL A 301 (-3.3A) None	1.11A	6b68D-5iy2A: 19.4	6b68D-5iy2A: 17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5iy2	BETA-LACTAMASE OXA-143 (Acinetobacter baumannii)	PF00905 (Transpeptidase)	6	SER A 81 SER A 128 ARG A 261 LYS A 218 GLY A 220 GLY A 222	KCX A 84 (-2.7A) GOL A 301 (-3.6A) GOL A 301 (-3.1A) GOL A 301 ( 4.7A) GOL A 301 (-3.3A) None	0.97A	6b68D-5iy2A: 19.4	6b68D-5iy2A: 17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5kzh	BETA-LACTAMASE (Acinetobacter baumannii)	PF00905 (Transpeptidase)	6	SER A 80 SER A 127 ARG A 260 LYS A 217 GLY A 219 ASP A 223	FMT A 301 (-2.5A) FMT A 301 (-3.3A) None KCX A 83 ( 4.9A) FMT A 301 (-3.3A) None	0.98A	6b68D-5kzhA: 19.6	6b68D-5kzhA: 17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5kzh	BETA-LACTAMASE (Acinetobacter baumannii)	PF00905 (Transpeptidase)	6	SER A 80 SER A 127 ARG A 260 LYS A 217 GLY A 219 GLY A 221	FMT A 301 (-2.5A) FMT A 301 (-3.3A) None KCX A 83 ( 4.9A) FMT A 301 (-3.3A) None	0.86A	6b68D-5kzhA: 19.6	6b68D-5kzhA: 17.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5ll7	BETA-LACTAMASE (Escherichia coli)	no annotation	9	SER A 70 SER A 130 ASN A 170 THR A 216 ARG A 220 LYS A 234 GLY A 236 THR A 237 GLU A 276	6YV A 301 (-1.7A) 6YV A 301 (-2.6A) 6YV A 301 (-2.9A) 6YV A 301 ( 4.2A) 6YV A 301 ( 3.7A) 6YV A 301 (-3.6A) 6YV A 301 ( 4.0A) 6YV A 301 (-3.6A) None	0.38A	6b68D-5ll7A: 40.2	6b68D-5ll7A: 40.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5lp4	PENICILLIN-BINDING PROTEIN 2 (PBP2) (Helicobacter pylori)	PF00905 (Transpeptidase) PF03717 (PBP_dimer)	5	SER A 311 SER A 366 THR A 498 LYS A 513 GLY A 515	None	0.63A	6b68D-5lp4A: 15.9	6b68D-5lp4A: 9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5tfq	BETA-LACTAMASE (Bacteroides cellulosilyticus)	PF13354 (Beta-lactamase2)	6	SER A 48 SER A 112 THR A 197 LYS A 215 GLY A 217 ASP A 220	PO4 A 301 (-3.8A) PO4 A 301 (-2.6A) PO4 A 301 ( 3.8A) PO4 A 301 (-3.2A) PO4 A 301 (-3.3A) None	0.56A	6b68D-5tfqA: 31.3	6b68D-5tfqA: 11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5tr7	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE (Vibrio cholerae)	PF00768 (Peptidase_S11) PF07943 (PBP5_C)	6	SER A 66 SER A 129 ARG A 267 LYS A 232 GLY A 234 GLU A 264	None None NO2 A 403 (-3.7A) None None NO2 A 403 (-4.2A)	0.83A	6b68D-5tr7A: 21.9	6b68D-5tr7A: 13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5tro	PENICILLIN-BINDING PROTEIN 1 (Staphylococcus aureus)	PF00905 (Transpeptidase) PF03717 (PBP_dimer)	5	SER A 314 SER A 368 LYS A 513 GLY A 515 THR A 516	None	0.36A	6b68D-5troA: 17.0	6b68D-5troA: 10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ty7	PENICILLIN-BINDING PROTEIN 4 (Staphylococcus aureus)	no annotation	6	SER A 75 SER A 139 LYS A 259 GLY A 261 ASP A 264 GLU A 297	NFF A 401 (-1.1A) NFF A 401 (-3.4A) NFF A 401 ( 4.8A) NFF A 401 (-3.7A) NFF A 401 ( 4.3A) None	0.69A	6b68D-5ty7A: 20.7	6b68D-5ty7A: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5u2g	PENICILLIN-BINDING PROTEIN 1A (Haemophilus influenzae)	PF00905 (Transpeptidase) PF00912 (Transgly) PF17092 (PCB_OB)	5	SER A 510 THR A 712 LYS A 728 GLY A 730 THR A 731	None None None None CL A 910 (-4.2A)	0.68A	6b68D-5u2gA: 16.6	6b68D-5u2gA: 6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5u47	PENICILLIN BINDING PROTEIN 2X (Streptococcus thermophilus)	PF00905 (Transpeptidase) PF03717 (PBP_dimer) PF03793 (PASTA)	6	SER A 343 SER A 402 THR A 532 LYS A 553 GLY A 555 THR A 556	None	0.62A	6b68D-5u47A: 16.4	6b68D-5u47A: 11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5vfd	BETA-LACTAMASE (Acinetobacter baumannii)	PF00905 (Transpeptidase)	6	SER A 81 SER A 128 ARG A 261 LYS A 218 GLY A 220 GLY A 222	9CP A 306 (-1.4A) 9CP A 306 (-2.8A) 9CP A 306 (-2.7A) 9CP A 306 (-3.0A) 9CP A 306 (-3.5A) 9CP A 306 ( 4.4A)	0.89A	6b68D-5vfdA: 18.9	6b68D-5vfdA: 17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5vpq	BETA-LACTAMASE (Paraburkholderia phymatum)	PF13354 (Beta-lactamase2)	8	SER A 58 SER A 119 ASN A 159 THR A 206 ARG A 210 GLY A 227 GLY A 229 ASP A 230	None None None None None None EDO A 304 (-3.4A) EDO A 304 (-3.7A)	0.64A	6b68D-5vpqA: 39.5	6b68D-5vpqA: 16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5x5g	BETA-LACTAMASE (Serratia marcescens)	PF13354 (Beta-lactamase2)	8	SER A 56 SER A 120 THR A 206 ARG A 210 LYS A 224 GLY A 226 ASP A 229 GLU A 270	OP0 A 305 (-1.5A) OP0 A 305 (-2.7A) OP0 A 305 (-3.6A) OP0 A 305 (-3.6A) OP0 A 305 (-3.4A) OP0 A 305 (-3.2A) OP0 A 305 (-3.6A) SO4 A 302 (-3.0A)	0.64A	6b68D-5x5gA: 32.6	6b68D-5x5gA: 15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5zqe	- (-)	no annotation	7	SER A 58 SER A 118 THR A 208 ARG A 257 LYS A 222 GLY A 224 ASP A 227	CES A 301 (-1.3A) CES A 301 ( 3.7A) CES A 301 (-4.3A) CES A 301 (-2.9A) None CES A 301 (-3.2A) None	0.81A	6b68D-5zqeA: 21.6	6b68D-5zqeA: undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6bu3	BETA-LACTAMASE (Escherichia coli)	no annotation	7	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 236 GLY A 238	3GK A 301 ( 3.8A) 3GK A 301 (-2.7A) 3GK A 301 (-3.9A) 3GK A 302 ( 4.3A) 3GK A 301 ( 4.1A) 3GK A 301 (-3.4A) 3GK A 301 (-3.6A)	0.47A	6b68D-6bu3A: 41.4	6b68D-6bu3A: 33.75

[["6B68_D_9F2D400_1","1alq","Staphylococcus aureus","CP254 BETA-LACTAMASE","PF13354(Beta-lactamase2)",5,"SER A  70;SER A 130;ASN A 170;LYS A 234;GLY A 236","None","0.42A","6b68D-1alqA:27.8","6b68D-1alqA:15.09"],["6B68_D_9F2D400_1","1bsg","Streptomyces albus","BETA LACTAMASE","PF13354(Beta-lactamase2)",8,"SER A  70;SER A 130;ASN A 170;THR A 216;ARG A 220;LYS A 234;GLY A 236;GLY A 238","None","0.58A","6b68D-1bsgA:41.7","6b68D-1bsgA:18.04"],["6B68_D_9F2D400_1","1bue","Enterobacter cloacae","PROTEIN (IMIPENEM-HYDROLYSING BETA-LACTAMASE)","PF13354(Beta-lactamase2)",7,"SER A  70;SER A 130;ASN A 170;THR A 216;ARG A 220;LYS A 234;GLY A 236","None","0.37A","6b68D-1bueA:38.5","6b68D-1bueA:16.27"],["6B68_D_9F2D400_1","1dy6","Serratia marcescens","CARBAPENEM-HYDROLYSING BETA-LACTAMASE SME-1","PF13354(Beta-lactamase2)",6,"SER A  70;SER A 130;ASN A 170;THR A 216;ARG A 220;GLY A 239","None","0.89A","6b68D-1dy6A:38.9","6b68D-1dy6A:16.09"],["6B68_D_9F2D400_1","1dy6","Serratia marcescens","CARBAPENEM-HYDROLYSING BETA-LACTAMASE SME-1","PF13354(Beta-lactamase2)",7,"SER A  70;SER A 130;ASN A 170;THR A 216;ARG A 220;LYS A 234;GLY A 236","None","0.42A","6b68D-1dy6A:38.9","6b68D-1dy6A:16.09"],["6B68_D_9F2D400_1","1e25","Pseudomonas aeruginosa","EXTENDED-SPECTRUM BETA-LACTAMASE PER-1","PF13354(Beta-lactamase2)",8,"SER A  70;SER A 130;THR A 216;ARG A 220;LYS A 234;GLY A 236;THR A 237;GLU A 276","SO4 A 500 (-3.1A);SO4 A 500 (-2.6A);SO4 A 500 ( 4.0A);SO4 A 500 ( 4.2A);SO4 A 500 (-3.2A);SO4 A 500 (-3.5A);SO4 A 500 (-3.5A);None","0.45A","6b68D-1e25A:31.4","6b68D-1e25A:11.35"],["6B68_D_9F2D400_1","1g68","Pseudomonas aeruginosa","BETA-LACTAMASE PSE-4","PF13354(Beta-lactamase2)",5,"SER A  70;SER A 130;ASN A 170;GLY A 236;GLY A 238","SO4 A 400 (-2.9A);SO4 A 400 (-2.7A);None;SO4 A 400 (-3.0A);None","0.62A","6b68D-1g68A:37.1","6b68D-1g68A:15.86"],["6B68_D_9F2D400_1","1hzo","Proteus vulgaris","BETA-LACTAMASE","PF13354(Beta-lactamase2)",8,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 236;GLY A 238;ASP A 240","MES A1000 (-3.1A);MES A1000 (-2.7A);None;MES A1000 (-3.7A);MES A1000 (-2.9A);MES A1000 (-3.1A);None;None","0.51A","6b68D-1hzoA:41.3","6b68D-1hzoA:22.58"],["6B68_D_9F2D400_1","1i2w","Bacillus licheniformis","BETA-LACTAMASE","PF13354(Beta-lactamase2)",6,"SER A  70;SER A 130;THR A 216;LYS A 234;GLY A 236;GLY A 238","CFX A1300 (-1.3A);CFX A1300 (-3.1A);CFX A1300 (-3.2A);CFX A1300 ( 3.9A);CFX A1300 (-3.3A);CFX A1300 ( 4.1A)","0.42A","6b68D-1i2wA:41.8","6b68D-1i2wA:17.48"],["6B68_D_9F2D400_1","1j9m","Streptomyces sp. K15","DD-TRANSPEPTIDASE","PF00768(Peptidase_S11)",6,"SER A  35;SER A  96;THR A 199;ARG A 248;LYS A 213;GLY A 215"," NA A 600 (-3.3A); NA A 600 (-3.1A); NA A 600 ( 4.5A); CL A 601 (-3.1A); NA A 600 (-3.4A); NA A 600 ( 3.6A)","0.89A","6b68D-1j9mA:22.5","6b68D-1j9mA:17.05"],["6B68_D_9F2D400_1","1j9m","Streptomyces sp. K15","DD-TRANSPEPTIDASE","PF00768(Peptidase_S11)",6,"SER A  96;THR A 199;ARG A 248;LYS A 213;GLY A 215;GLY A 217"," NA A 600 (-3.1A); NA A 600 ( 4.5A); CL A 601 (-3.1A); NA A 600 (-3.4A); NA A 600 ( 3.6A);None","0.67A","6b68D-1j9mA:22.5","6b68D-1j9mA:17.05"],["6B68_D_9F2D400_1","1n4o","Stenotrophomonas maltophilia","L2 BETA-LACTAMASE","PF13354(Beta-lactamase2)",6,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 236","SO4 A1002 (-2.9A);SO4 A1002 (-3.1A);None;SO4 A1002 ( 4.8A);SO4 A1002 (-3.6A);SO4 A1002 (-3.2A)","0.32A","6b68D-1n4oA:37.6","6b68D-1n4oA:17.72"],["6B68_D_9F2D400_1","1n9b","Klebsiella pneumoniae","BETA-LACTAMASE SHV-2","PF13354(Beta-lactamase2)",5,"SER A  70;SER A 130;ASN A 170;LYS A 234;GLY A 236","EPE A 400 (-3.7A);EPE A 400 (-2.5A);None;EPE A 400 (-3.1A);EPE A 400 (-3.1A)","0.69A","6b68D-1n9bA:34.1","6b68D-1n9bA:17.12"],["6B68_D_9F2D400_1","1nrf","Bacillus licheniformis","REGULATORY PROTEIN BLAR1","PF00905(Transpeptidase)",5,"SER A 402;SER A 450;LYS A 539;GLY A 541;THR A 542","None","0.49A","6b68D-1nrfA:18.9","6b68D-1nrfA:14.34"],["6B68_D_9F2D400_1","1w5d","Bacillus subtilis","PENICILLIN-BINDING PROTEIN","PF02113(Peptidase_S13)",5,"SER A  52;SER A 299;THR A 394;LYS A 411;GLY A 413","None","0.35A","6b68D-1w5dA:20.2","6b68D-1w5dA:11.48"],["6B68_D_9F2D400_1","1xp4","Streptococcus pneumoniae","D-ALANYL-D-ALANINE CARBOXYPEPTIDASE","PF00768(Peptidase_S11);PF07943(PBP5_C)",8,"SER A  56;SER A 119;THR A 221;ARG A 278;LYS A 239;GLY A 241;THR A 242;ASP A 244","SO4 A 464 (-3.4A);SO4 A 464 (-3.4A);SO4 A 464 ( 4.0A);SO4 A 464 ( 4.1A);SO4 A 464 (-3.5A);SO4 A 464 ( 3.8A);SO4 A 464 (-4.0A);None","0.62A","6b68D-1xp4A:20.5","6b68D-1xp4A:13.98"],["6B68_D_9F2D400_1","1zg4","Escherichia coli","BETA-LACTAMASE TEM","PF13354(Beta-lactamase2)",6,"SER A  70;SER A 130;ASN A 170;LYS A 234;GLY A 236;GLY A 238","None","0.32A","6b68D-1zg4A:36.7","6b68D-1zg4A:14.69"],["6B68_D_9F2D400_1","2c6w","Streptococcus pneumoniae","PENICILLIN-BINDING PROTEIN 1A","PF00905(Transpeptidase)",5,"SER B 370;SER B 428;THR B 543;LYS B 557;GLY B 559"," CL B 704 (-3.5A); CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 ( 4.0A)","0.68A","6b68D-2c6wB:16.5","6b68D-2c6wB:12.46"],["6B68_D_9F2D400_1","2c6w","Streptococcus pneumoniae","PENICILLIN-BINDING PROTEIN 1A","PF00905(Transpeptidase)",5,"SER B 428;THR B 543;LYS B 557;GLY B 559;THR B 560"," CL B 704 (-3.4A); CL B 704 ( 4.8A);None; CL B 704 ( 4.0A); CL B 704 ( 4.8A)","0.69A","6b68D-2c6wB:16.5","6b68D-2c6wB:12.46"],["6B68_D_9F2D400_1","2cc1","Mycolicibacterium fortuitum","BETA-LACTAMASE","PF13354(Beta-lactamase2)",8,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 236;GLY A 238;ASP A 240","None","0.36A","6b68D-2cc1A:39.4","6b68D-2cc1A:16.79"],["6B68_D_9F2D400_1","2fff","Streptococcus pneumoniae","PENICILLIN-BINDING PROTEIN 1B","PF00905(Transpeptidase)",6,"SER B 460;SER B 516;THR B 629;LYS B 651;GLY B 653;THR B 654","None","0.54A","6b68D-2fffB:16.3","6b68D-2fffB:9.71"],["6B68_D_9F2D400_1","2iwb","Staphylococcus aureus","METHICILLIN RESISTANCE MECR1 PROTEIN","PF00905(Transpeptidase)",6,"SER A 391;SER A 439;LYS A 528;GLY A 530;THR A 531;GLY A 532","GOL A 604 ( 2.7A);GOL A 604 (-2.6A);GOL A 604 (-2.9A);GOL A 605 ( 3.2A);GOL A 604 ( 3.6A);None","0.38A","6b68D-2iwbA:18.9","6b68D-2iwbA:17.83"],["6B68_D_9F2D400_1","2jch","Streptococcus pneumoniae","PENICILLIN-BINDING PROTEIN 1B","PF00905(Transpeptidase);PF00912(Transgly)",6,"SER A 460;SER A 516;THR A 629;LYS A 651;GLY A 653;THR A 654","PL7 A1793 (-1.4A);PL7 A1793 (-3.0A);PL7 A1793 ( 4.1A);PL7 A1793 ( 4.1A);PL7 A1793 (-3.3A);PL7 A1793 (-4.1A)","0.56A","6b68D-2jchA:15.3","6b68D-2jchA:8.06"],["6B68_D_9F2D400_1","2v2f","Streptococcus pneumoniae","PENICILLIN BINDING PROTEIN 1A","PF00905(Transpeptidase)",5,"SER F 428;THR F 543;LYS F 557;GLY F 559;THR F 560","MES F1653 (-3.1A);MES F1653 (-3.7A);MES F1653 ( 4.0A);MES F1653 (-3.6A);MES F1653 (-3.6A)","0.64A","6b68D-2v2fF:17.5","6b68D-2v2fF:12.50"],["6B68_D_9F2D400_1","2wae","Streptococcus pneumoniae","PENICILLIN-BINDING PROTEIN 2B","PF00905(Transpeptidase);PF03717(PBP_dimer)",5,"SER A 386;SER A 443;THR A 600;LYS A 615;GLY A 617","None","0.50A","6b68D-2waeA:15.6","6b68D-2waeA:8.60"],["6B68_D_9F2D400_1","2wuq","Streptomyces cacaoi","BETA-LACTAMASE REGULATORY PROTEIN BLAB","PF13354(Beta-lactamase2)",7,"SER A  47;SER A 109;ARG A 239;LYS A 254;GLY A 256;THR A 257;GLU A 295","None","0.57A","6b68D-2wuqA:29.0","6b68D-2wuqA:14.55"],["6B68_D_9F2D400_1","2wyx","Escherichia coli","BETA-LACTAMSE TOHO-1","PF13354(Beta-lactamase2)",8,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 236;GLY A 238;ASP A 240","None","0.52A","6b68D-2wyxA:40.6","6b68D-2wyxA:18.53"],["6B68_D_9F2D400_1","2z2m","Streptococcus pneumoniae","PENICILLIN-BINDING PROTEIN 2X","PF00905(Transpeptidase)",6,"SER B 337;SER B 395;THR B 526;LYS B 547;GLY B 549;THR B 550","CDS B 901 ( 1.3A);CDS B 901 ( 3.2A);CDS B 901 ( 4.1A);CDS B 901 ( 3.9A);CDS B 901 ( 3.4A);CDS B 901 ( 3.6A)","0.40A","6b68D-2z2mB:16.1","6b68D-2z2mB:13.87"],["6B68_D_9F2D400_1","3a3i","Haemophilus influenzae","PENICILLIN-BINDING PROTEIN 4","PF02113(Peptidase_S13)",5,"SER A  69;SER A 310;THR A 401;LYS A 420;GLY A 422","AIX A 501 (-1.3A);AIX A 501 (-2.8A);AIX A 501 ( 4.0A);AIX A 501 ( 3.8A);AIX A 501 (-3.4A)","0.37A","6b68D-3a3iA:20.1","6b68D-3a3iA:12.53"],["6B68_D_9F2D400_1","3bfg","Citrobacter sedlakii","CLASS A BETA-LACTAMASE SED1","PF13354(Beta-lactamase2)",7,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 236;ASP A 240","MER A 301 (-1.3A);MER A 301 (-2.6A);MER A 301 (-2.6A);MER A 301 (-3.6A);MER A 301 (-3.2A);MER A 301 (-3.0A);None","0.64A","6b68D-3bfgA:41.0","6b68D-3bfgA:18.10"],["6B68_D_9F2D400_1","3byd","Klebsiella oxytoca","BETA-LACTAMASE OXY-1","PF13354(Beta-lactamase2)",8,"SER A  73;SER A 133;ASN A 173;THR A 219;LYS A 237;GLY A 239;GLY A 241;ASP A 242","SO4 A 301 (-2.9A);SO4 A 301 (-2.8A);None;SO4 A 301 ( 4.0A);SO4 A 301 (-3.1A);SO4 A 301 (-3.3A);None;None","0.45A","6b68D-3bydA:41.5","6b68D-3bydA:19.09"],["6B68_D_9F2D400_1","3cjm","Enterococcus faecalis","PUTATIVE BETA-LACTAMASE","PF13354(Beta-lactamase2)",6,"SER A 108;SER A 169;ARG A 244;LYS A 257;GLY A 259;ASP A 262","NO3 A   1 (-2.9A);None;EDO A   6 ( 4.5A);None;None;None","0.59A","6b68D-3cjmA:26.0","6b68D-3cjmA:13.86"],["6B68_D_9F2D400_1","3dwk","Staphylococcus aureus","PENICILLIN-BINDING PROTEIN 2","PF00905(Transpeptidase);PF00912(Transgly)",5,"SER A 454;LYS A 583;GLY A 585;THR A 586;GLY A 587","SO4 A  26 (-3.1A);SO4 A  26 ( 4.2A);SO4 A  26 (-3.3A);SO4 A  26 (-3.5A);None","0.53A","6b68D-3dwkA:17.8","6b68D-3dwkA:8.84"],["6B68_D_9F2D400_1","3dwz","Mycobacterium tuberculosis","BETA-LACTAMASE","PF13354(Beta-lactamase2)",11,"SER A  84;SER A 142;ASN A 186;THR A 232;ARG A 236;LYS A 250;GLY A 252;THR A 253;GLY A 254;ASP A 255;GLU A 292","DWZ A 400 (-1.3A);DWZ A 400 (-2.7A);DWZ A 400 ( 4.0A);DWZ A 400 ( 4.5A);DWZ A 400 ( 4.3A);DWZ A 400 ( 3.8A);DWZ A 400 (-3.3A);DWZ A 400 (-4.1A);None;None;None","0.33A","6b68D-3dwzA:48.5","6b68D-3dwzA:100.00"],["6B68_D_9F2D400_1","3hum","Staphylococcus aureus","PENICILLIN-BINDING PROTEIN 4","PF00768(Peptidase_S11);PF09211(DUF1958)",6,"SER A  75;SER A 139;LYS A 259;GLY A 261;ASP A 264;GLU A 297","CEW A 501 (-2.6A);CEW A 501 (-3.4A);CEW A 501 ( 4.4A);CEW A 501 (-3.1A);None;CEW A 501 (-3.2A)","0.72A","6b68D-3humA:22.5","6b68D-3humA:11.70"],["6B68_D_9F2D400_1","3lez","Oceanobacillus iheyensis","BETA-LACTAMASE","PF13354(Beta-lactamase2)",6,"SER A  85;ASN A 183;THR A 229;LYS A 247;GLY A 249;GLY A 251","EPE A 305 (-3.4A);None;EPE A 305 ( 3.9A);EPE A 305 (-3.1A);EPE A 305 (-3.4A);None","0.41A","6b68D-3lezA:40.7","6b68D-3lezA:18.97"],["6B68_D_9F2D400_1","3p09","Francisella tularensis","BETA-LACTAMASE","PF13354(Beta-lactamase2)",9,"SER A  61;SER A 122;ASN A 162;THR A 208;ARG A 212;LYS A 226;GLY A 228;THR A 229;GLU A 268","SO4 A 288 (-3.1A);SO4 A 288 (-2.7A);None;SO4 A 288 ( 4.8A);SO4 A 288 ( 4.4A);SO4 A 288 (-3.5A);SO4 A 288 (-3.3A);SO4 A 288 (-3.4A);None","0.33A","6b68D-3p09A:39.3","6b68D-3p09A:25.37"],["6B68_D_9F2D400_1","3q7z","Staphylococcus aureus","BETA-LACTAMASE REGULATORY PROTEIN BLAR1","PF00905(Transpeptidase)",6,"SER A 389;SER A 437;LYS A 526;GLY A 528;THR A 529;GLY A 530","BOU A 584 (-1.4A);BOU A 584 (-2.8A);BOU A 584 (-3.3A);BOU A 584 (-3.7A);BOU A 584 (-3.6A);BOU A 584 ( 3.9A)","0.43A","6b68D-3q7zA:17.7","6b68D-3q7zA:14.22"],["6B68_D_9F2D400_1","3qhy","Bacillus anthracis","BETA-LACTAMASE","PF13354(Beta-lactamase2)",7,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 236;GLY A 238","None","0.34A","6b68D-3qhyA:41.7","6b68D-3qhyA:23.04"],["6B68_D_9F2D400_1","3qnb","Escherichia coli","OXACILLINASE","PF00905(Transpeptidase)",6,"SER A  67;SER A 115;ARG A 250;LYS A 205;GLY A 207;GLY A 209","KCX A  70 ( 2.7A);KCX A  70 ( 4.6A);SO4 A   4 (-3.4A);KCX A  70 ( 4.7A);None;None","0.97A","6b68D-3qnbA:18.7","6b68D-3qnbA:14.34"],["6B68_D_9F2D400_1","3ue1","Acinetobacter baumannii","PENICILLIN-BINDING PROTEIN 1A","PF00905(Transpeptidase);PF00912(Transgly);PF17092(PCB_OB)",5,"SER A 434;SER A 487;LYS A 669;GLY A 671;THR A 672","UE1 A 998 (-1.7A);UE1 A 998 (-3.3A);UE1 A 998 ( 3.8A);UE1 A 998 (-3.4A);UE1 A 998 (-3.6A)","0.70A","6b68D-3ue1A:14.7","6b68D-3ue1A:7.87"],["6B68_D_9F2D400_1","3v39","Bdellovibrio bacteriovorus","D-ALANYL-D-ALANINE CARBOXYPEPTIDASE","PF02113(Peptidase_S13)",5,"SER A  70;SER A 251;THR A 342;LYS A 357;GLY A 359","TAU A 501 (-1.5A);TAU A 501 (-2.6A);None;TAU A 501 ( 4.3A);TAU A 501 (-3.5A)","0.29A","6b68D-3v39A:17.0","6b68D-3v39A:11.89"],["6B68_D_9F2D400_1","3vsk","Staphylococcus aureus","PENICILLIN-BINDING PROTEIN 3","PF00905(Transpeptidase);PF03717(PBP_dimer)",5,"SER A 392;SER A 448;THR A 603;LYS A 618;GLY A 620","None","0.50A","6b68D-3vskA:17.0","6b68D-3vskA:9.00"],["6B68_D_9F2D400_1","3w4q","Burkholderia multivorans","BETA-LACTAMASE","PF13354(Beta-lactamase2)",9,"SER A  70;SER A 130;ASN A 170;ARG A 220;LYS A 234;GLY A 236;THR A 237;GLY A 238;ASP A 240","None","0.36A","6b68D-3w4qA:41.2","6b68D-3w4qA:17.18"],["6B68_D_9F2D400_1","3zdj","synthetic construct","ENCA BETA-LACTAMASE","PF13354(Beta-lactamase2)",6,"SER A  70;SER A 130;ASN A 170;LYS A 234;GLY A 236;GLY A 238","SO4 A1291 (-3.4A);SO4 A1291 (-3.1A);None;SO4 A1291 (-3.3A);SO4 A1291 (-3.3A);None","0.30A","6b68D-3zdjA:36.8","6b68D-3zdjA:15.09"],["6B68_D_9F2D400_1","3zg8","Listeria monocytogenes","PENICILLIN-BINDING PROTEIN 4","PF00905(Transpeptidase);PF00912(Transgly)",5,"SER B 394;SER B 449;THR B 561;LYS B 575;GLY B 577","AIX B 800 (-0.2A);AIX B 800 (-2.4A);AIX B 800 ( 3.8A);AIX B 800 ( 4.0A);AIX B 800 ( 3.7A)","0.41A","6b68D-3zg8B:16.4","6b68D-3zg8B:9.30"],["6B68_D_9F2D400_1","3zny","Klebsiella pneumoniae","CTX-M-12A ENZYME","PF13354(Beta-lactamase2)",7,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 236;GLY A 238","None","0.47A","6b68D-3znyA:41.5","6b68D-3znyA:22.93"],["6B68_D_9F2D400_1","3zvt","Actinomadura sp. R39","D-ALANYL-D-ALANINE CARBOXYPEPTIDASE","PF02113(Peptidase_S13)",5,"SER A  49;SER A 298;THR A 393;LYS A 410;GLY A 412","B07 A 500 (-1.4A);B07 A 500 (-1.4A);B07 A 500 ( 4.8A);B07 A 500 (-1.6A);B07 A 500 (-3.2A)","0.63A","6b68D-3zvtA:20.2","6b68D-3zvtA:10.47"],["6B68_D_9F2D400_1","4c6y","synthetic construct","BETA-LACTAMASE","PF13354(Beta-lactamase2)",9,"SER A  70;SER A 130;ASN A 170;THR A 216;ARG A 220;LYS A 234;GLY A 236;THR A 237;GLY A 238","PEG A 307 (-2.4A);PEG A 307 (-2.4A);PEG A 307 ( 4.3A);PEG A 307 ( 4.3A);PEG A 307 ( 3.6A);PEG A 307 ( 3.4A);PEG A 307 (-2.7A);PEG A 307 (-3.9A);None","0.31A","6b68D-4c6yA:40.4","6b68D-4c6yA:25.82"],["6B68_D_9F2D400_1","4c75","synthetic construct","BETA-LACTAMASE","PF13354(Beta-lactamase2)",8,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 236;THR A 237;GLY A 238"," NA A 294 ( 2.5A);SO4 A 291 (-2.8A);None;SO4 A 291 ( 4.1A);SO4 A 291 (-3.4A); NA A 294 ( 3.2A);SO4 A 291 ( 3.4A);None","0.42A","6b68D-4c75A:40.3","6b68D-4c75A:24.39"],["6B68_D_9F2D400_1","4d2o","Citrobacter freundii","PER-2 BETA-LACTAMASE","PF13354(Beta-lactamase2)",7,"ARG A 240;THR A 216;ARG A 220;LYS A 234;GLY A 236;THR A 237;GLU A 276","None","1.14A","6b68D-4d2oA:31.1","6b68D-4d2oA:13.73"],["6B68_D_9F2D400_1","4d2o","Citrobacter freundii","PER-2 BETA-LACTAMASE","PF13354(Beta-lactamase2)",8,"SER A  70;SER A 130;THR A 216;ARG A 220;LYS A 234;GLY A 236;THR A 237;GLU A 276","None","0.57A","6b68D-4d2oA:31.1","6b68D-4d2oA:13.73"],["6B68_D_9F2D400_1","4ev4","Serratia fonticola","CARBAPENEM-HYDROLIZING BETA-LACTAMASE SFC-1","PF13354(Beta-lactamase2)",8,"SER A  70;SER A 130;ASN A 170;THR A 216;ARG A 220;LYS A 234;GLY A 236;THR A 237","MER A 401 (-1.3A);MER A 401 (-2.8A);MER A 401 (-2.9A);MER A 401 ( 3.9A);MER A 401 ( 3.9A);MER A 401 (-3.0A);MER A 401 (-3.6A);MER A 401 (-3.7A)","0.42A","6b68D-4ev4A:39.5","6b68D-4ev4A:18.10"],["6B68_D_9F2D400_1","4ewf","Sphaerobacter thermophilus","BETA-LACTAMASE","PF13354(Beta-lactamase2)",6,"SER A  49;SER A 110;ARG A 197;LYS A 213;GLY A 215;GLU A 250","SO4 A 301 (-3.1A);SO4 A 301 (-3.1A);SO4 A 301 ( 3.7A);SO4 A 301 (-3.0A);SO4 A 301 (-3.5A);None","0.33A","6b68D-4ewfA:30.8","6b68D-4ewfA:15.45"],["6B68_D_9F2D400_1","4fsf","Pseudomonas aeruginosa","PENICILLIN-BINDING PROTEIN 3","PF00905(Transpeptidase);PF03717(PBP_dimer)",5,"SER A 294;SER A 349;LYS A 484;GLY A 486;THR A 487","0W0 A 601 (-1.4A);0W0 A 601 (-3.1A);0W0 A 601 (-3.0A);0W0 A 601 (-3.4A);0W0 A 601 (-3.7A)","0.38A","6b68D-4fsfA:17.0","6b68D-4fsfA:12.79"],["6B68_D_9F2D400_1","4gn2","Pseudomonas aeruginosa","OXACILLINASE","PF00905(Transpeptidase)",6,"SER A  63;SER A 112;LYS A 208;GLY A 210;THR A 211;GLY A 212","KCX A  66 ( 2.9A);KCX A  66 ( 3.5A);KCX A  66 ( 4.5A);None;None;None","0.35A","6b68D-4gn2A:17.3","6b68D-4gn2A:20.81"],["6B68_D_9F2D400_1","4ied","Fusobacterium nucleatum","CLASS D BETA-LACTAMASE","PF00905(Transpeptidase)",6,"SER A  57;SER A 106;ARG A 239;LYS A 196;GLY A 198;ASP A 202","KCX A  60 ( 2.7A);KCX A  60 ( 3.4A);None;KCX A  60 ( 4.5A);None;None","1.12A","6b68D-4iedA:19.2","6b68D-4iedA:15.51"],["6B68_D_9F2D400_1","4k0x","Acinetobacter baumannii","BETA-LACTAMASE","PF00905(Transpeptidase)",6,"SER A  79;SER A 126;ARG A 259;LYS A 216;GLY A 218;ASP A 222","KCX A  82 (-2.5A);BCT A 301 (-2.8A);BCT A 301 (-3.0A);BCT A 301 (-3.0A);BCT A 301 (-3.4A);None","0.89A","6b68D-4k0xA:19.3","6b68D-4k0xA:16.15"],["6B68_D_9F2D400_1","4mnr","Eggerthella lenta","PEPTIDOGLYCAN GLYCOSYLTRANSFERASE","PF00905(Transpeptidase)",5,"SER A 237;THR A 383;LYS A 397;GLY A 399;THR A 400","None","0.61A","6b68D-4mnrA:16.7","6b68D-4mnrA:13.93"],["6B68_D_9F2D400_1","4oh0","Acinetobacter baumannii","BETA-LACTAMASE OXA-58","PF00905(Transpeptidase)",5,"SER A  83;SER A 130;LYS A 220;GLY A 222;GLY A 224","KCX A  86 ( 2.6A);KCX A  86 ( 3.3A); CL A 301 ( 4.4A); CL A 301 (-3.6A);None","0.58A","6b68D-4oh0A:17.8","6b68D-4oh0A:12.87"],["6B68_D_9F2D400_1","4oon","Pseudomonas aeruginosa","PENICILLIN-BINDING PROTEIN 1A","PF00905(Transpeptidase);PF00912(Transgly);PF17092(PCB_OB)",6,"SER A 461;SER A 520;THR A 680;LYS A 695;GLY A 697;THR A 698","2U4 A 901 (-1.3A);2U4 A 901 (-3.6A);2U4 A 901 (-4.1A);2U4 A 901 ( 4.3A);2U4 A 901 (-3.7A);2U4 A 901 (-3.8A)","0.70A","6b68D-4oonA:16.1","6b68D-4oonA:7.94"],["6B68_D_9F2D400_1","4ovd","Atopobium parvulum","PEPTIDOGLYCAN GLYCOSYLTRANSFERASE","PF00905(Transpeptidase);PF03717(PBP_dimer)",6,"SER A 361;THR A 486;LYS A 500;GLY A 502;THR A 503;GLY A 504"," CA A 601 ( 3.8A); CA A 601 ( 4.7A); CA A 601 ( 4.1A); CA A 601 ( 4.2A);None;None","1.11A","6b68D-4ovdA:17.0","6b68D-4ovdA:9.37"],["6B68_D_9F2D400_1","4ra7","Atopobium parvulum","PEPTIDOGLYCAN GLYCOSYLTRANSFERASE","PF00905(Transpeptidase)",7,"SER A 682;SER A 737;THR A 876;LYS A 890;GLY A 892;THR A 893;ASP A 895","NXU A1001 (-1.3A);NXU A1001 (-3.2A);NXU A1001 (-4.0A);NXU A1001 (-3.5A);NXU A1001 (-3.4A);NXU A1001 (-3.9A);NXU A1001 (-3.1A)","0.58A","6b68D-4ra7A:16.2","6b68D-4ra7A:13.23"],["6B68_D_9F2D400_1","4yfm","Mycobacteroides abscessus","BETA-LACTAMASE","PF13354(Beta-lactamase2)",7,"SER A  71;SER A 131;ASN A 171;THR A 215;LYS A 233;GLY A 235;GLY A 237","ACT A 301 (-3.5A);ACT A 301 (-2.9A);None;ACT A 301 (-3.7A);ACT A 301 (-3.4A);ACT A 301 (-3.3A);None","0.34A","6b68D-4yfmA:39.7","6b68D-4yfmA:17.83"],["6B68_D_9F2D400_1","4ztk","Legionella pneumophila","CELL DIVISION PROTEIN FTSI\/PENICILLIN BINDING PROTEIN 2","PF00905(Transpeptidase)",6,"SER A 400;SER A 454;THR A 554;LYS A 568;GLY A 570;GLU A 617","NHE A 901 (-3.2A);NHE A 901 (-2.9A);NHE A 901 ( 4.2A);NHE A 901 (-3.0A);NHE A 901 (-3.6A);None","1.02A","6b68D-4ztkA:16.1","6b68D-4ztkA:11.74"],["6B68_D_9F2D400_1","4ztk","Legionella pneumophila","CELL DIVISION PROTEIN FTSI\/PENICILLIN BINDING PROTEIN 2","PF00905(Transpeptidase)",6,"SER A 400;SER A 454;THR A 554;LYS A 568;GLY A 570;THR A 571","NHE A 901 (-3.2A);NHE A 901 (-2.9A);NHE A 901 ( 4.2A);NHE A 901 (-3.0A);NHE A 901 (-3.6A);NHE A 901 (-3.8A)","0.49A","6b68D-4ztkA:16.1","6b68D-4ztkA:11.74"],["6B68_D_9F2D400_1","5aqa","synthetic construct","OFF7_DB04V3","PF00023(Ank);PF12796(Ank_2);PF13354(Beta-lactamase2)",6,"SER A 200;SER A 260;ASN A 300;LYS A 364;GLY A 366;GLY A 368","None","0.42A","6b68D-5aqaA:35.8","6b68D-5aqaA:11.27"],["6B68_D_9F2D400_1","5boh","Acinetobacter baumannii","BETA-LACTAMASE","PF00905(Transpeptidase)",6,"SER A  83;SER A 130;ARG A 263;LYS A 220;GLY A 222;GLY A 224","KCX A  86 ( 2.7A);KCX A  86 ( 3.5A);None;KCX A  86 ( 4.5A);None;None","0.90A","6b68D-5bohA:18.3","6b68D-5bohA:12.15"],["6B68_D_9F2D400_1","5cer","Bdellovibrio bacteriovorus","BD0816","PF02113(Peptidase_S13)",5,"SER A 239;THR A 330;LYS A 345;GLY A 347;THR A 348","None","0.31A","6b68D-5cerA:17.8","6b68D-5cerA:11.61"],["6B68_D_9F2D400_1","5ctm","Bacillus pumilus","BETA-LACTAMASE","PF00905(Transpeptidase)",5,"SER A 101;SER A 149;LYS A 239;GLY A 241;GLY A 243","KCX A 104 (-2.2A);FLC A 301 (-2.5A);FLC A 301 (-3.0A);FLC A 301 (-3.2A);None","0.61A","6b68D-5ctmA:17.4","6b68D-5ctmA:13.45"],["6B68_D_9F2D400_1","5cxw","Mycobacterium tuberculosis","PENICILLIN-BINDING PROTEIN 1A","PF00905(Transpeptidase)",5,"SER A 345;SER A 398;LYS A 539;GLY A 541;THR A 542","35P A 702 (-1.3A);35P A 702 (-2.9A);35P A 702 (-3.3A);35P A 702 (-3.5A);35P A 702 (-3.7A)","0.38A","6b68D-5cxwA:17.1","6b68D-5cxwA:13.23"],["6B68_D_9F2D400_1","5e2e","Yersinia enterocolitica","BETA-LACTAMASE","PF13354(Beta-lactamase2)",8,"SER A  47;SER A 107;ASN A 147;THR A 193;ARG A 251;GLY A 213;GLY A 215;ASP A 216","None","0.95A","6b68D-5e2eA:41.2","6b68D-5e2eA:14.50"],["6B68_D_9F2D400_1","5e2e","Yersinia enterocolitica","BETA-LACTAMASE","PF13354(Beta-lactamase2)",8,"SER A  47;SER A 107;ASN A 147;THR A 193;LYS A 211;GLY A 213;GLY A 215;ASP A 216","None","0.48A","6b68D-5e2eA:41.2","6b68D-5e2eA:14.50"],["6B68_D_9F2D400_1","5e2h","Mycolicibacterium smegmatis","BETA-LACTAMASE","PF00144(Beta-lactamase)",5,"SER A  58;ARG A 341;LYS A 307;GLY A 309;ASP A 312","None","0.66A","6b68D-5e2hA:15.2","6b68D-5e2hA:15.58"],["6B68_D_9F2D400_1","5e43","Streptosporangium roseum","BETA-LACTAMASE","PF13354(Beta-lactamase2)",8,"SER A  70;SER A 131;ASN A 171;THR A 217;ARG A 221;LYS A 235;GLY A 237;THR A 238","ACT A 311 (-3.2A);ACT A 311 (-3.0A);None;ACT A 311 ( 3.9A);ACT A 311 (-4.5A);ACT A 311 (-3.3A);ACT A 311 (-3.2A);ACT A 311 (-3.8A)","0.35A","6b68D-5e43A:41.1","6b68D-5e43A:15.11"],["6B68_D_9F2D400_1","5eoe","Pseudomonas aeruginosa","BETA-LACTAMASE","PF13354(Beta-lactamase2)",6,"SER A  62;SER A 123;ASN A 163;THR A 209;LYS A 227;GLY A 229","CIT A 303 (-2.8A);CIT A 303 (-2.5A);None;CIT A 303 (-3.2A);CIT A 303 (-3.5A);CIT A 303 (-3.5A)","0.38A","6b68D-5eoeA:39.4","6b68D-5eoeA:16.08"],["6B68_D_9F2D400_1","5f83","Pseudomonas aeruginosa","BETA-LACTAMASE","PF13354(Beta-lactamase2)",6,"SER A  64;SER A 125;THR A 211;LYS A 229;GLY A 231;THR A 232","IM2 A 301 (-1.4A);IM2 A 301 (-2.7A);IM2 A 301 (-4.1A);IM2 A 301 (-3.3A);IM2 A 301 (-3.3A);IM2 A 301 (-4.0A)","0.40A","6b68D-5f83A:38.3","6b68D-5f83A:15.99"],["6B68_D_9F2D400_1","5gl9","Burkholderia thailandensis","BETA-LACTAMASE","PF13354(Beta-lactamase2)",10,"SER A  70;SER A 130;ASN A 170;THR A 216;ARG A 220;LYS A 234;GLY A 236;THR A 237;GLY A 238;ASP A 240","None","0.37A","6b68D-5gl9A:41.1","6b68D-5gl9A:18.28"],["6B68_D_9F2D400_1","5hlb","Escherichia coli","PENICILLIN-BINDING PROTEIN 1B","PF00905(Transpeptidase);PF00912(Transgly);PF14814(UB2H)",6,"SER A 510;SER A 572;THR A 682;LYS A 698;GLY A 700;THR A 701","AZR A 902 (-1.4A);AZR A 902 ( 3.7A);AZR A 902 (-3.4A);AZR A 902 ( 4.5A);AZR A 902 (-3.3A);AZR A 902 (-4.3A)","0.58A","6b68D-5hlbA:17.6","6b68D-5hlbA:8.41"],["6B68_D_9F2D400_1","5hw3","Burkholderia vietnamiensis","BETA-LACTAMASE","PF13354(Beta-lactamase2)",6,"SER A  70;ASN A 171;ARG A 219;GLY A 235;THR A 236;GLU A 273","SO4 A 301 (-2.7A);ACT A 310 (-4.0A);SO4 A 301 ( 4.2A);SO4 A 301 (-3.4A);SO4 A 301 (-3.5A);None","0.27A","6b68D-5hw3A:38.4","6b68D-5hw3A:40.70"],["6B68_D_9F2D400_1","5hw3","Burkholderia vietnamiensis","BETA-LACTAMASE","PF13354(Beta-lactamase2)",6,"SER A  70;SER A 131;ARG A 219;GLY A 235;THR A 236;GLU A 273","SO4 A 301 (-2.7A);SO4 A 301 (-2.6A);SO4 A 301 ( 4.2A);SO4 A 301 (-3.4A);SO4 A 301 (-3.5A);None","0.49A","6b68D-5hw3A:38.4","6b68D-5hw3A:40.70"],["6B68_D_9F2D400_1","5hx9","Burkholderia vietnamiensis","BETA-LACTAMASE","PF13354(Beta-lactamase2)",5,"ASN A 170;LYS A 234;GLY A 236;THR A 237;GLY A 238","None;EDO A 303 (-2.6A);None;None;None","0.47A","6b68D-5hx9A:38.7","6b68D-5hx9A:21.14"],["6B68_D_9F2D400_1","5ihv","Burkholderia ambifaria","BETA-LACTAMASE","PF13354(Beta-lactamase2)",5,"ASN A 147;LYS A 211;GLY A 213;THR A 214;GLY A 215","None;EDO A 302 (-2.8A);None;None;None","0.48A","6b68D-5ihvA:39.0","6b68D-5ihvA:21.74"],["6B68_D_9F2D400_1","5iy2","Acinetobacter baumannii","BETA-LACTAMASE OXA-143","PF00905(Transpeptidase)",6,"SER A  81;SER A 128;ARG A 261;LYS A 218;GLY A 220;ASP A 224","KCX A  84 (-2.7A);GOL A 301 (-3.6A);GOL A 301 (-3.1A);GOL A 301 ( 4.7A);GOL A 301 (-3.3A);None","1.11A","6b68D-5iy2A:19.4","6b68D-5iy2A:17.70"],["6B68_D_9F2D400_1","5iy2","Acinetobacter baumannii","BETA-LACTAMASE OXA-143","PF00905(Transpeptidase)",6,"SER A  81;SER A 128;ARG A 261;LYS A 218;GLY A 220;GLY A 222","KCX A  84 (-2.7A);GOL A 301 (-3.6A);GOL A 301 (-3.1A);GOL A 301 ( 4.7A);GOL A 301 (-3.3A);None","0.97A","6b68D-5iy2A:19.4","6b68D-5iy2A:17.70"],["6B68_D_9F2D400_1","5kzh","Acinetobacter baumannii","BETA-LACTAMASE","PF00905(Transpeptidase)",6,"SER A  80;SER A 127;ARG A 260;LYS A 217;GLY A 219;ASP A 223","FMT A 301 (-2.5A);FMT A 301 (-3.3A);None;KCX A  83 ( 4.9A);FMT A 301 (-3.3A);None","0.98A","6b68D-5kzhA:19.6","6b68D-5kzhA:17.22"],["6B68_D_9F2D400_1","5kzh","Acinetobacter baumannii","BETA-LACTAMASE","PF00905(Transpeptidase)",6,"SER A  80;SER A 127;ARG A 260;LYS A 217;GLY A 219;GLY A 221","FMT A 301 (-2.5A);FMT A 301 (-3.3A);None;KCX A  83 ( 4.9A);FMT A 301 (-3.3A);None","0.86A","6b68D-5kzhA:19.6","6b68D-5kzhA:17.22"],["6B68_D_9F2D400_1","5ll7","Escherichia coli","BETA-LACTAMASE","no annotation",9,"SER A  70;SER A 130;ASN A 170;THR A 216;ARG A 220;LYS A 234;GLY A 236;THR A 237;GLU A 276","6YV A 301 (-1.7A);6YV A 301 (-2.6A);6YV A 301 (-2.9A);6YV A 301 ( 4.2A);6YV A 301 ( 3.7A);6YV A 301 (-3.6A);6YV A 301 ( 4.0A);6YV A 301 (-3.6A);None","0.38A","6b68D-5ll7A:40.2","6b68D-5ll7A:40.00"],["6B68_D_9F2D400_1","5lp4","Helicobacter pylori","PENICILLIN-BINDING PROTEIN 2 (PBP2)","PF00905(Transpeptidase);PF03717(PBP_dimer)",5,"SER A 311;SER A 366;THR A 498;LYS A 513;GLY A 515","None","0.63A","6b68D-5lp4A:15.9","6b68D-5lp4A:9.67"],["6B68_D_9F2D400_1","5tfq","Bacteroides cellulosilyticus","BETA-LACTAMASE","PF13354(Beta-lactamase2)",6,"SER A  48;SER A 112;THR A 197;LYS A 215;GLY A 217;ASP A 220","PO4 A 301 (-3.8A);PO4 A 301 (-2.6A);PO4 A 301 ( 3.8A);PO4 A 301 (-3.2A);PO4 A 301 (-3.3A);None","0.56A","6b68D-5tfqA:31.3","6b68D-5tfqA:11.76"],["6B68_D_9F2D400_1","5tr7","Vibrio cholerae","D-ALANYL-D-ALANINE CARBOXYPEPTIDASE","PF00768(Peptidase_S11);PF07943(PBP5_C)",6,"SER A  66;SER A 129;ARG A 267;LYS A 232;GLY A 234;GLU A 264","None;None;NO2 A 403 (-3.7A);None;None;NO2 A 403 (-4.2A)","0.83A","6b68D-5tr7A:21.9","6b68D-5tr7A:13.71"],["6B68_D_9F2D400_1","5tro","Staphylococcus aureus","PENICILLIN-BINDING PROTEIN 1","PF00905(Transpeptidase);PF03717(PBP_dimer)",5,"SER A 314;SER A 368;LYS A 513;GLY A 515;THR A 516","None","0.36A","6b68D-5troA:17.0","6b68D-5troA:10.38"],["6B68_D_9F2D400_1","5ty7","Staphylococcus aureus","PENICILLIN-BINDING PROTEIN 4","no annotation",6,"SER A  75;SER A 139;LYS A 259;GLY A 261;ASP A 264;GLU A 297","NFF A 401 (-1.1A);NFF A 401 (-3.4A);NFF A 401 ( 4.8A);NFF A 401 (-3.7A);NFF A 401 ( 4.3A);None","0.69A","6b68D-5ty7A:20.7","6b68D-5ty7A:19.32"],["6B68_D_9F2D400_1","5u2g","Haemophilus influenzae","PENICILLIN-BINDING PROTEIN 1A","PF00905(Transpeptidase);PF00912(Transgly);PF17092(PCB_OB)",5,"SER A 510;THR A 712;LYS A 728;GLY A 730;THR A 731","None;None;None;None; CL A 910 (-4.2A)","0.68A","6b68D-5u2gA:16.6","6b68D-5u2gA:6.99"],["6B68_D_9F2D400_1","5u47","Streptococcus thermophilus","PENICILLIN BINDING PROTEIN 2X","PF00905(Transpeptidase);PF03717(PBP_dimer);PF03793(PASTA)",6,"SER A 343;SER A 402;THR A 532;LYS A 553;GLY A 555;THR A 556","None","0.62A","6b68D-5u47A:16.4","6b68D-5u47A:11.75"],["6B68_D_9F2D400_1","5vfd","Acinetobacter baumannii","BETA-LACTAMASE","PF00905(Transpeptidase)",6,"SER A  81;SER A 128;ARG A 261;LYS A 218;GLY A 220;GLY A 222","9CP A 306 (-1.4A);9CP A 306 (-2.8A);9CP A 306 (-2.7A);9CP A 306 (-3.0A);9CP A 306 (-3.5A);9CP A 306 ( 4.4A)","0.89A","6b68D-5vfdA:18.9","6b68D-5vfdA:17.22"],["6B68_D_9F2D400_1","5vpq","Paraburkholderia phymatum","BETA-LACTAMASE","PF13354(Beta-lactamase2)",8,"SER A  58;SER A 119;ASN A 159;THR A 206;ARG A 210;GLY A 227;GLY A 229;ASP A 230","None;None;None;None;None;None;EDO A 304 (-3.4A);EDO A 304 (-3.7A)","0.64A","6b68D-5vpqA:39.5","6b68D-5vpqA:16.34"],["6B68_D_9F2D400_1","5x5g","Serratia marcescens","BETA-LACTAMASE","PF13354(Beta-lactamase2)",8,"SER A  56;SER A 120;THR A 206;ARG A 210;LYS A 224;GLY A 226;ASP A 229;GLU A 270","OP0 A 305 (-1.5A);OP0 A 305 (-2.7A);OP0 A 305 (-3.6A);OP0 A 305 (-3.6A);OP0 A 305 (-3.4A);OP0 A 305 (-3.2A);OP0 A 305 (-3.6A);SO4 A 302 (-3.0A)","0.64A","6b68D-5x5gA:32.6","6b68D-5x5gA:15.56"],["6B68_D_9F2D400_1","5zqe","-","-","no annotation",7,"SER A  58;SER A 118;THR A 208;ARG A 257;LYS A 222;GLY A 224;ASP A 227","CES A 301 (-1.3A);CES A 301 ( 3.7A);CES A 301 (-4.3A);CES A 301 (-2.9A);None;CES A 301 (-3.2A);None","0.81A","6b68D-5zqeA:21.6","6b68D-5zqeA:undetectable"],["6B68_D_9F2D400_1","6bu3","Escherichia coli","BETA-LACTAMASE","no annotation",7,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 236;GLY A 238","3GK A 301 ( 3.8A);3GK A 301 (-2.7A);3GK A 301 (-3.9A);3GK A 302 ( 4.3A);3GK A 301 ( 4.1A);3GK A 301 (-3.4A);3GK A 301 (-3.6A)","0.47A","6b68D-6bu3A:41.4","6b68D-6bu3A:33.75"]]