SIMILAR PATTERNS OF AMINO ACIDS FOR 6AUU_B_MTLB805

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hn0 CHONDROITIN ABC
LYASE I

(Proteus
vulgaris) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt) 		4 SER A 112
ARG A 212
GLN A 318
ASP A 218
 None
 1.16A 6auuB-1hn0A:
0.0		 6auuB-1hn0A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iw8 ACID PHOSPHATASE

(Shimwellia
blattae) 		PF01569
(PAP2) 		4 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.32A 6auuB-1iw8A:
undetectable		 6auuB-1iw8A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1knr L-ASPARTATE OXIDASE

(Escherichia
coli) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.32A 6auuB-1knrA:
0.0		 6auuB-1knrA:
22.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lzx NITRIC-OXIDE
SYNTHASE

(Rattus
norvegicus) 		PF02898
(NO_synthase) 		8 SER A 477
ARG A 481
ASN A 498
GLN A 500
PHE A 501
ASN A 569
ASP A 709
TRP A 711
 None
 0.29A 6auuB-1lzxA:
62.5		 6auuB-1lzxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE

(Homo sapiens) 		PF02898
(NO_synthase) 		6 SER A 246
ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.47A 6auuB-1m9qA:
59.3		 6auuB-1m9qA:
64.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpo MALTOPORIN

(Escherichia
coli) 		PF02264
(LamB) 		4 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 432 (-3.3A)
None
None
None
 1.29A 6auuB-1mpoA:
0.0		 6auuB-1mpoA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)

(Homo sapiens) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		4 ASN A 578
GLN A 576
PHE A 577
ASP A 573
 None
 1.21A 6auuB-1qgrA:
0.0		 6auuB-1qgrA:
18.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qw5 NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Mus musculus) 		PF02898
(NO_synthase) 		5 SER A 256
ARG A 260
PHE A 280
ASN A 348
TRP A 490
 None
 0.63A 6auuB-1qw5A:
58.1		 6auuB-1qw5A:
63.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rrh SEED LIPOXYGENASE-3

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 SER A 517
ASN A 373
GLN A 716
ASN A 521
 None
 1.30A 6auuB-1rrhA:
0.0		 6auuB-1rrhA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1twb STRINGENT STARVATION
PROTEIN B HOMOLOG

(Haemophilus
influenzae) 		PF04386
(SspB) 		4 ASN A  72
GLN A  63
PHE A  71
ASN A  39
 None
 1.09A 6auuB-1twbA:
undetectable		 6auuB-1twbA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ut9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		4 SER A 680
GLN A 687
PHE A 683
ASN A 681
 None
 1.34A 6auuB-1ut9A:
undetectable		 6auuB-1ut9A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uwy CARBOXYPEPTIDASE M

(Homo sapiens) 		PF00246
(Peptidase_M14)
PF13620
(CarboxypepD_reg) 		4 SER A 197
ASN A 185
GLN A 249
PHE A 183
 None
 1.15A 6auuB-1uwyA:
undetectable		 6auuB-1uwyA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrq SARCOSINE OXIDASE
ALPHA SUBUNIT

(Corynebacterium
sp. U-96) 		PF01571
(GCV_T)
PF08669
(GCV_T_C)
PF12831
(FAD_oxidored)
PF13510
(Fer2_4) 		4 ARG A 253
ASN A 381
PHE A 403
ASP A 397
 None
 1.29A 6auuB-1vrqA:
undetectable		 6auuB-1vrqA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xr4 PUTATIVE CITRATE
LYASE ALPHA
CHAIN/CITRATE-ACP
TRANSFERASE

(Salmonella
enterica) 		PF04223
(CitF) 		4 SER A 297
ASN A 361
PHE A 268
ASP A 266
 None
 1.33A 6auuB-1xr4A:
undetectable		 6auuB-1xr4A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yvl SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION
1-ALPHA/BETA

(Homo sapiens) 		PF00017
(SH2)
PF01017
(STAT_alpha)
PF02864
(STAT_bind)
PF02865
(STAT_int) 		4 GLN A  95
PHE A  94
ASN A  89
ASP A  92
 None
 1.28A 6auuB-1yvlA:
undetectable		 6auuB-1yvlA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z3v CELLULASE

(Phanerochaete
chrysosporium) 		PF00840
(Glyco_hydro_7) 		4 SER A 321
GLN A 329
PHE A 326
ASN A 320
 None
 1.15A 6auuB-1z3vA:
undetectable		 6auuB-1z3vA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ckr ENDOGLUCANASE E-5

(Thermobifida
fusca) 		PF00150
(Cellulase) 		4 SER A 392
GLN A 402
PHE A 401
ASN A 390
 None
 1.11A 6auuB-2ckrA:
undetectable		 6auuB-2ckrA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fml MUTT/NUDIX FAMILY
PROTEIN

(Enterococcus
faecalis) 		PF00293
(NUDIX) 		4 ARG A 153
PHE A 227
ASN A 195
ASP A 199
 None
 1.01A 6auuB-2fmlA:
undetectable		 6auuB-2fmlA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gv0 LYSOZYME C

(Pelodiscus
sinensis) 		PF00062
(Lys) 		4 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.21A 6auuB-2gv0A:
undetectable		 6auuB-2gv0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuj LIPOXYGENASE L-5

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 SER A 512
ASN A 368
GLN A 711
ASN A 516
 None
 1.25A 6auuB-2iujA:
undetectable		 6auuB-2iujA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuk SEED LIPOXYGENASE

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 SER A 524
ASN A 379
GLN A 723
ASN A 528
 None
 1.23A 6auuB-2iukA:
undetectable		 6auuB-2iukA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lbf 60S ACIDIC RIBOSOMAL
PROTEIN P2

(Homo sapiens) 		PF00428
(Ribosomal_60s) 		4 SER B 117
ASN B 147
ASN B 115
ASP B 122
 None
 1.02A 6auuB-2lbfB:
undetectable		 6auuB-2lbfB:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mpr MALTOPORIN

(Salmonella
enterica) 		PF02264
(LamB) 		4 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.22A 6auuB-2mprA:
undetectable		 6auuB-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA

(Homo sapiens) 		PF00899
(ThiF)
PF08825
(E2_bind)
PF13416
(SBP_bac_8) 		4 SER B1353
ARG B1355
GLN B1153
ASP B1208
 None
 1.31A 6auuB-2nvuB:
undetectable		 6auuB-2nvuB:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2psb YERB PROTEIN

(Bacillus
subtilis) 		PF11258
(DUF3048)
PF17479
(DUF3048_C) 		4 SER A  93
PHE A  96
ASN A  94
ASP A  97
 None
 1.17A 6auuB-2psbA:
undetectable		 6auuB-2psbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qe9 UNCHARACTERIZED
PROTEIN YIZA

(Bacillus
subtilis) 		PF05163
(DinB) 		4 SER A  79
ARG A  12
PHE A  82
ASN A  80
 None
 1.29A 6auuB-2qe9A:
undetectable		 6auuB-2qe9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica) 		PF04962
(KduI) 		4 ARG A 190
ASN A 217
GLN A 195
PHE A 191
 SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
 0.95A 6auuB-2qjvA:
undetectable		 6auuB-2qjvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4g TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila) 		PF12009
(Telomerase_RBD) 		4 ASN A 317
GLN A 282
PHE A 318
ASN A 322
 None
 1.28A 6auuB-2r4gA:
undetectable		 6auuB-2r4gA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v3s SERINE/THREONINE-PRO
TEIN KINASE OSR1

(Homo sapiens) 		PF12202
(OSR1_C) 		4 ARG A 441
GLN A 523
ASN A 448
ASP A 449
 None
 1.28A 6auuB-2v3sA:
undetectable		 6auuB-2v3sA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE

(Campylobacter
jejuni) 		PF06002
(CST-I) 		4 ASN A 116
GLN A 111
ASN A  80
ASP A 107
 None
 1.33A 6auuB-2wqqA:
undetectable		 6auuB-2wqqA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x63 ALPHA-2,3-/2,8-SIALY
LTRANSFERASE

(Campylobacter
jejuni) 		PF06002
(CST-I) 		4 ASN A 116
GLN A 111
ASN A  80
ASP A 107
 None
 1.29A 6auuB-2x63A:
undetectable		 6auuB-2x63A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y5w KINESIN HEAVY CHAIN

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		4 SER A 311
ARG A  20
PHE A  19
ASN A 316
 None
 1.33A 6auuB-2y5wA:
undetectable		 6auuB-2y5wA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ysd MEMBRANE-ASSOCIATED
GUANYLATE KINASE, WW
AND PDZ
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00397
(WW) 		4 SER A  40
PHE A  31
ASP A  33
TRP A  19
 None
 1.34A 6auuB-2ysdA:
undetectable		 6auuB-2ysdA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ

(Vibrio
vulnificus) 		PF11612
(T2SSJ) 		4 ARG B 151
ASN B 160
PHE B 152
ASP B 154
 None
 1.23A 6auuB-3cfiB:
undetectable		 6auuB-3cfiB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3clw CONSERVED EXPORTED
PROTEIN

(Bacteroides
fragilis) 		PF14587
(Glyco_hydr_30_2) 		4 ARG A  52
GLN A 133
PHE A  55
ASN A 113
 None
 1.22A 6auuB-3clwA:
undetectable		 6auuB-3clwA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dal PR DOMAIN ZINC
FINGER PROTEIN 1

(Homo sapiens) 		PF00856
(SET) 		4 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.15A 6auuB-3dalA:
undetectable		 6auuB-3dalA:
19.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 ARG A 266
ASN A 283
PHE A 286
TRP A 496
 AT2  A 906 (-3.6A)
None
None
None
 1.05A 6auuB-3e7gA:
57.4		 6auuB-3e7gA:
65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 ASN A 283
PHE A 286
ASN A 354
TRP A 496
 None
 1.02A 6auuB-3e7gA:
57.4		 6auuB-3e7gA:
65.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7n LIPASE

(Penicillium
expansum) 		PF01764
(Lipase_3) 		4 SER A 229
ARG A 224
ASN A 232
ASP A 188
 None
 1.29A 6auuB-3g7nA:
undetectable		 6auuB-3g7nA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila) 		no annotation 4 SER A 204
ARG A 175
ASN A 235
ASP A 261
 None
 1.11A 6auuB-3gozA:
undetectable		 6auuB-3gozA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5g MYOSIN REGULATORY
LIGHT CHAIN LC-2,
MANTLE MUSCLE

(Todarodes
pacificus) 		PF13405
(EF-hand_6) 		4 ASN B 138
GLN B 136
PHE B 137
ASP B  95
 None
 1.30A 6auuB-3i5gB:
undetectable		 6auuB-3i5gB:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihv SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ASN A 384
GLN A 382
ASN A 523
TRP A 515
 None
 1.09A 6auuB-3ihvA:
undetectable		 6auuB-3ihvA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ix1 N-FORMYL-4-AMINO-5-A
MINOMETHYL-2-METHYLP
YRIMIDINE BINDING
PROTEIN

(Bacillus
halodurans) 		PF09084
(NMT1) 		4 SER A 109
ARG A 112
ASN A 289
PHE A 294
 None
 1.20A 6auuB-3ix1A:
undetectable		 6auuB-3ix1A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kci PROBABLE E3
UBIQUITIN-PROTEIN
LIGASE HERC2

(Homo sapiens) 		PF00415
(RCC1) 		4 SER A4182
ARG A4238
GLN A4207
ASP A4171
 None
 1.26A 6auuB-3kciA:
undetectable		 6auuB-3kciA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyd SUMO-ACTIVATING
ENZYME SUBUNIT 2

(Homo sapiens) 		PF00899
(ThiF)
PF14732
(UAE_UbL) 		4 ARG B  59
ASN B  56
GLN B 195
ASP B  53
 None
 1.16A 6auuB-3kydB:
undetectable		 6auuB-3kydB:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lrv PRE-MRNA-SPLICING
FACTOR 19

(Saccharomyces
cerevisiae) 		no annotation 4 ASN A 497
PHE A 496
ASN A 187
ASP A 494
 None
None
SO4  A  69 (-4.3A)
None
 1.26A 6auuB-3lrvA:
undetectable		 6auuB-3lrvA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9v UNCHARACTERIZED
PROTEIN

(Marinobacter
hydrocarbonoclasticus) 		PF10604
(Polyketide_cyc2) 		4 ASN A  10
PHE A 112
ASN A 139
ASP A 143
 None
 1.16A 6auuB-3p9vA:
undetectable		 6auuB-3p9vA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pgl CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1

(Homo sapiens) 		PF03031
(NIF) 		4 SER A 208
ASN A 187
ASN A 207
ASP A  96
 None
None
MG  A   1 (-2.7A)
MG  A   1 (-2.5A)
 0.98A 6auuB-3pglA:
undetectable		 6auuB-3pglA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3to3 PETROBACTIN
BIOSYNTHESIS PROTEIN
ASBB

(Bacillus
anthracis) 		PF04183
(IucA_IucC)
PF06276
(FhuF) 		4 ASN A 175
GLN A 171
PHE A 170
ASN A 303
 None
 1.20A 6auuB-3to3A:
undetectable		 6auuB-3to3A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cp2 EPITHELIAL ADHESIN 9

([Candida]
glabrata) 		PF10528
(GLEYA) 		4 SER A 171
PHE A 147
ASN A 172
ASP A 258
 None
None
None
GAL  A1296 ( 3.5A)
 1.26A 6auuB-4cp2A:
undetectable		 6auuB-4cp2A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0k PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3-LIKE PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 SER B 538
ARG B 540
GLN B 484
ASN B 523
 None
 1.14A 6auuB-4d0kB:
undetectable		 6auuB-4d0kB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dq6 PUTATIVE PYRIDOXAL
PHOSPHATE-DEPENDENT
TRANSFERASE

(Clostridioides
difficile) 		PF00155
(Aminotran_1_2) 		4 SER A 356
ASN A 352
ASN A 355
TRP A 326
 None
 1.34A 6auuB-4dq6A:
undetectable		 6auuB-4dq6A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fn5 ELONGATION FACTOR G
1

(Pseudomonas
aeruginosa) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF03144
(GTP_EFTU_D2)
PF03764
(EFG_IV)
PF14492
(EFG_II) 		4 ARG A  29
ASN A 272
ASN A 142
ASP A 145
 None
 1.27A 6auuB-4fn5A:
undetectable		 6auuB-4fn5A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gdz UNCHARACTERIZED
PROTEIN

(Bacteroides
eggerthii) 		PF14059
(DUF4251) 		4 SER A 181
ASN A  73
ASN A 161
ASP A 160
 None
 1.27A 6auuB-4gdzA:
undetectable		 6auuB-4gdzA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gr6 ATRBCX2

(Arabidopsis
thaliana) 		PF02341
(RcbX) 		4 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.22A 6auuB-4gr6A:
undetectable		 6auuB-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hxe PUTATIVE
UNCHARACTERIZED
PROTEIN PH0594

(Pyrococcus
horikoshii) 		PF00326
(Peptidase_S9)
PF07676
(PD40) 		4 SER B  62
GLN B  86
ASN B  43
ASP B  60
 None
 1.18A 6auuB-4hxeB:
undetectable		 6auuB-4hxeB:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ine PROTEIN PMT-2

(Caenorhabditis
elegans) 		PF08241
(Methyltransf_11) 		4 SER A 257
ARG A 179
GLN A 115
ASN A 258
 None
 1.16A 6auuB-4ineA:
undetectable		 6auuB-4ineA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irx SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN

(Caulobacter
vibrioides) 		PF13407
(Peripla_BP_4) 		4 ASN A 231
GLN A 278
ASN A  45
ASP A 125
 INS  A 401 (-3.9A)
INS  A 401 (-3.1A)
None
INS  A 401 (-2.8A)
 1.27A 6auuB-4irxA:
undetectable		 6auuB-4irxA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m00 SERINE-RICH ADHESIN
FOR PLATELETS

(Staphylococcus
aureus) 		PF05345
(He_PIG) 		4 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
SUC  A 804 (-3.3A)
 1.18A 6auuB-4m00A:
undetectable		 6auuB-4m00A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m01 SERINE-RICH ADHESIN
FOR PLATELETS

(Staphylococcus
aureus) 		no annotation 4 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
GOL  A 602 (-3.3A)
 1.17A 6auuB-4m01A:
undetectable		 6auuB-4m01A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mhp GLUTAMINYL CYCLASE,
PUTATIVE

(Ixodes
scapularis) 		PF04389
(Peptidase_M28) 		4 SER A 337
ARG A  53
GLN A  47
ASN A 338
 None
 1.25A 6auuB-4mhpA:
undetectable		 6auuB-4mhpA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oi3 NICKEL RESPONSIVE
PROTEIN

(Streptomyces
coelicolor) 		PF14026
(DUF4242) 		4 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.31A 6auuB-4oi3A:
undetectable		 6auuB-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oyd APOPTOSIS REGULATOR
BHRF1
COMPUTATIONALLY
DESIGNED INHIBITOR

(Human
gammaherpesvirus
4;
synthetic
construct) 		PF00452
(Bcl-2)
no annotation 		4 SER B 100
ARG A  60
ASN A  61
ASP B 105
 None
 1.28A 6auuB-4oydB:
undetectable		 6auuB-4oydB:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p6v NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT C

(Vibrio cholerae) 		PF04205
(FMN_bind) 		4 SER C 103
ARG C 117
GLN C 110
ASN C 120
 None
 1.28A 6auuB-4p6vC:
undetectable		 6auuB-4p6vC:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pvi GH62 HYDROLASE

(Mycothermus
thermophilus) 		PF03664
(Glyco_hydro_62) 		4 ASN A  -6
GLN A  -2
PHE A  -3
TRP A  32
 None
 1.32A 6auuB-4pviA:
undetectable		 6auuB-4pviA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9s NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT C

(Vibrio cholerae) 		PF04205
(FMN_bind) 		4 SER C 103
ARG C 117
GLN C 110
ASN C 120
 None
 1.30A 6auuB-4u9sC:
undetectable		 6auuB-4u9sC:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uac CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-)

([Eubacterium]
rectale) 		PF13416
(SBP_bac_8) 		4 GLN A 394
PHE A 189
ASN A 191
ASP A 190
 EDO  A 504 (-3.3A)
None
ACR  A 501 (-3.3A)
EDO  A 504 ( 4.2A)
 1.21A 6auuB-4uacA:
undetectable		 6auuB-4uacA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzz TRAP TRANSPORTER
SOLUTE BINDING
PROTEIN

(Bordetella
bronchiseptica) 		PF03480
(DctP) 		4 GLN A 264
PHE A 267
ASN A 149
TRP A 256
 None
 1.29A 6auuB-4yzzA:
undetectable		 6auuB-4yzzA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z9p NUCLEOPROTEIN

(Zaire
ebolavirus) 		PF05505
(Ebola_NP) 		4 SER A 279
GLN A 315
PHE A 313
ASN A 278
 None
 1.34A 6auuB-4z9pA:
undetectable		 6auuB-4z9pA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a53 REGULATOR OF
RIBOSOME
BIOSYNTHESIS
RIBOSOME BIOGENESIS
PROTEIN RPF2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF04939
(RRS1)
PF04427
(Brix) 		4 SER C 169
ARG C 166
ASN A  25
ASP C 171
 SO4  C1254 (-3.2A)
SO4  C1254 (-3.1A)
None
None
 0.96A 6auuB-5a53C:
undetectable		 6auuB-5a53C:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aex AMMONIUM TRANSPORTER
MEP2

(Saccharomyces
cerevisiae) 		PF00909
(Ammonium_transp) 		4 SER A 116
ASN A 174
PHE A  89
ASP A 122
 None
 1.11A 6auuB-5aexA:
undetectable		 6auuB-5aexA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dku PREX DNA POLYMERASE

(Plasmodium
falciparum) 		PF00476
(DNA_pol_A)
PF01612
(DNA_pol_A_exo1) 		4 SER A 202
ASN A 114
PHE A 113
ASN A 201
 None
 1.17A 6auuB-5dkuA:
undetectable		 6auuB-5dkuA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5du3 PLASMA PROTEASE C1
INHIBITOR

(Homo sapiens) 		PF00079
(Serpin) 		4 SER A 198
ASN A 269
GLN A 201
TRP A 243
 None
 1.34A 6auuB-5du3A:
undetectable		 6auuB-5du3A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqn FRBJ

(Streptomyces
rubellomurinus) 		PF02668
(TauD) 		4 ARG A 203
GLN A 115
ASP A 152
TRP A 311
 None
None
MG  A 401 (-3.5A)
None
 1.02A 6auuB-5eqnA:
undetectable		 6auuB-5eqnA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gs0 TOLL-LIKE RECEPTOR 3

(Homo sapiens) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 SER A 317
GLN A 352
ASN A 291
TRP A 353
 None
None
NAG  A 810 (-2.7A)
None
 1.12A 6auuB-5gs0A:
undetectable		 6auuB-5gs0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5haf DEUBIQUITINASE SSEL

(Salmonella
enterica) 		no annotation 4 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.30A 6auuB-5hafA:
undetectable		 6auuB-5hafA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hnz PROTEIN CLARET
SEGREGATIONAL,PROTEI
N CLARET
SEGREGATIONAL,PLUS-E
ND DIRECTED
KINESIN-1/KINESIN-14
,PROTEIN CLARET
SEGREGATIONAL,PROTEI
N CLARET
SEGREGATIONAL

(Drosophila
melanogaster;
Rattus
norvegicus) 		PF00225
(Kinesin) 		4 SER K 319
ARG K  32
PHE K  31
ASN K 324
 None
 1.23A 6auuB-5hnzK:
undetectable		 6auuB-5hnzK:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j55 CAROTENOID OXYGENASE

(Novosphingobium
aromaticivorans) 		PF03055
(RPE65) 		4 ARG A 356
GLN A 417
PHE A 354
ASN A 122
 None
 1.10A 6auuB-5j55A:
undetectable		 6auuB-5j55A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jse PHIAB6 TAILSPIKE

(unidentified
phage) 		PF12708
(Pectate_lyase_3) 		4 SER A 191
ARG A 189
GLN A 242
ASN A 192
 None
MLA  A 601 (-2.9A)
None
None
 1.30A 6auuB-5jseA:
undetectable		 6auuB-5jseA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1

(Saccharomyces
cerevisiae) 		no annotation 4 ASN 1  92
PHE 1  91
ASN 1  99
ASP 1  98
 None
 1.19A 6auuB-5oqj1:
undetectable		 6auuB-5oqj1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1

(Saccharomyces
cerevisiae) 		no annotation 4 ASN 1  92
PHE 1  91
ASN 1  99
ASP 1  98
 None
 1.19A 6auuB-5oqm1:
undetectable		 6auuB-5oqm1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqr CONDENSIN COMPLEX
SUBUNIT 3

(Schizosaccharomyces
pombe) 		no annotation 4 SER A 188
ARG A 160
PHE A 192
ASN A 187
 None
 1.23A 6auuB-5oqrA:
undetectable		 6auuB-5oqrA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t4y SUSC HOMOLOG

(Bacteroides
thetaiotaomicron) 		no annotation 4 SER D 343
ASN D 309
GLN D 307
ASN D 366
 None
 1.28A 6auuB-5t4yD:
undetectable		 6auuB-5t4yD:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1

(Glycine max) 		no annotation 4 SER A 498
ASN A 355
GLN A 697
ASN A 502
 None
 1.27A 6auuB-5tr0A:
undetectable		 6auuB-5tr0A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubw DEUBIQUITINASE SSEL

(Salmonella
enterica) 		no annotation 4 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.23A 6auuB-5ubwA:
undetectable		 6auuB-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uow N-METHYL-D-ASPARTATE
RECEPTOR SUBUNIT
NR1-8A

(Xenopus laevis) 		PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd) 		4 SER A 686
ARG A 521
ASN A 518
ASP A 730
 None
 1.27A 6auuB-5uowA:
undetectable		 6auuB-5uowA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v7i SERINE
HYDROXYMETHYLTRANSFE
RASE, MITOCHONDRIAL

(Homo sapiens) 		no annotation 4 SER A  97
ARG A 104
GLN A 324
PHE A 320
 None
 1.30A 6auuB-5v7iA:
undetectable		 6auuB-5v7iA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgb CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
ANTI-CRISPR PROTEIN
(ACRIIC1)

(Neisseria
meningitidis;
Neisseria
meningitidis) 		PF13395
(HNH_4)
no annotation 		4 ASN A  88
PHE A  87
ASN A  13
ASP B  44
 SO4  A 203 (-3.9A)
None
None
None
 1.15A 6auuB-5vgbA:
undetectable		 6auuB-5vgbA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w3f TUBULIN ALPHA-1
CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 SER A 224
GLN A  15
PHE A 225
ASN A 227
 None
None
GTP  A 502 (-3.8A)
None
 1.14A 6auuB-5w3fA:
undetectable		 6auuB-5w3fA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xb6 UNCHARACTERIZED
PROTEIN YCJY

(Escherichia
coli) 		no annotation 4 SER A 146
ARG A 149
ASN A 143
ASP A 261
 None
 1.31A 6auuB-5xb6A:
undetectable		 6auuB-5xb6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13

(Homo sapiens) 		no annotation 4 SER A  29
PHE A  30
ASN A  32
ASP A  33
 None
 1.29A 6auuB-5xg8A:
undetectable		 6auuB-5xg8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjg VACUOLAR PROTEIN 8
NUCLEUS-VACUOLE
JUNCTION PROTEIN 1

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00514
(Arm)
no annotation 		4 SER A 280
ARG A 242
GLN B 308
ASN B 304
 None
 0.85A 6auuB-5xjgA:
undetectable		 6auuB-5xjgA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Komagataella
phaffii;
Komagataella
phaffii) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 SER A 664
GLN B1065
PHE B1086
ASN A 743
 None
 1.32A 6auuB-5xogA:
undetectable		 6auuB-5xogA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xu1 ABC TRANSPORTER
PERMEAE

(Streptococcus
pneumoniae) 		no annotation 4 ARG M 240
ASN M  56
GLN M  54
ASN M 242
 None
 1.16A 6auuB-5xu1M:
undetectable		 6auuB-5xu1M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yh5 NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Staphylococcus
aureus) 		no annotation 4 ASN A 450
GLN A 130
ASN A 310
ASP A 308
 None
 1.25A 6auuB-5yh5A:
undetectable		 6auuB-5yh5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b7k ENDO-ALPHA-(1->5)-L-
ARABINANASE

(Bacillus
licheniformis) 		no annotation 4 SER A 120
ASN A 127
GLN A 125
PHE A 126
 None
 1.29A 6auuB-6b7kA:
undetectable		 6auuB-6b7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d3i -

(-) 		no annotation 4 GLN A  53
PHE A 140
ASN A 265
ASP A 264
 None
 1.33A 6auuB-6d3iA:
undetectable		 6auuB-6d3iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6erc PEROXINECTIN A

(Dictyostelium
discoideum) 		no annotation 4 ARG A 322
ASN A 403
GLN A 405
ASP A 409
 HEM  A 604 (-2.4A)
HEM  A 604 ( 4.4A)
None
None
 1.19A 6auuB-6ercA:
undetectable		 6auuB-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6evj RNA-DIRECTED RNA
POLYMERASE CATALYTIC
SUBUNIT

(Influenza A
virus) 		no annotation 4 SER B 345
ARG B 316
ASN B 314
ASN B 346
 None
 1.17A 6auuB-6evjB:
undetectable		 6auuB-6evjB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fik POLYKETIDE SYNTHASE

(Cercospora
nicotianae) 		no annotation 4 SER A 507
ASN A 581
ASN A 508
ASP A 467
 None
 1.34A 6auuB-6fikA:
undetectable		 6auuB-6fikA:
undetectable