SIMILAR PATTERNS OF AMINO ACIDS FOR 6A93_B_8NUB3001_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jym PEPTIDE DEFORMYLASE

(Plasmodium
falciparum) 		PF01327
(Pep_deformylase) 		4 ILE A 141
PHE A 194
ASN A  83
TYR A 175
 None
 1.19A 6a93B-1jymA:
undetectable		 6a93B-1jymA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r4y RIBONUCLEASE
ALPHA-SARCIN

(Aspergillus
giganteus) 		no annotation 4 ILE A  55
PHE A  57
ASN A  73
TYR A 110
 None
 1.10A 6a93B-1r4yA:
undetectable		 6a93B-1r4yA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y7p HYPOTHETICAL PROTEIN
AF1403

(Archaeoglobus
fulgidus) 		PF01842
(ACT) 		4 ASP A  18
ILE A  61
ASN A  11
TYR A  70
 None
 1.17A 6a93B-1y7pA:
undetectable		 6a93B-1y7pA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yck PEPTIDOGLYCAN
RECOGNITION PROTEIN

(Homo sapiens) 		PF01510
(Amidase_2) 		4 ASP A  81
ILE A 124
ASN A  58
TYR A  85
 None
 0.98A 6a93B-1yckA:
undetectable		 6a93B-1yckA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gbx BIPHENYL
2,3-DIOXYGENASE
ALPHA SUBUNIT

(Sphingobium
yanoikuyae) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		4 ASP A 422
ILE A  33
PHE A 299
ASN A  12
 None
 1.13A 6a93B-2gbxA:
undetectable		 6a93B-2gbxA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gdu SUCROSE
PHOSPHORYLASE

(Bifidobacterium
adolescentis) 		PF00128
(Alpha-amylase)
PF09244
(DUF1964) 		4 ASP A  12
ILE A 411
ASN A 397
TYR A 405
 None
 1.24A 6a93B-2gduA:
undetectable		 6a93B-2gduA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gop TRILOBED PROTEASE

(Pyrococcus
furiosus) 		PF07676
(PD40) 		4 ASP A 259
ILE A 294
PHE A 277
TYR A 247
 None
 1.25A 6a93B-2gopA:
undetectable		 6a93B-2gopA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iy8 PROTEIN PM0188

(Pasteurella
multocida) 		PF11477
(PM0188) 		4 ILE A  71
PHE A  79
ASN A  41
TYR A  31
 None
 1.15A 6a93B-2iy8A:
undetectable		 6a93B-2iy8A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lbp LEUCINE-BINDING
PROTEIN

(Escherichia
coli) 		PF13458
(Peripla_BP_6) 		4 ASP A  32
ILE A  39
ASN A  24
TYR A 281
 None
 1.17A 6a93B-2lbpA:
undetectable		 6a93B-2lbpA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o14 HYPOTHETICAL PROTEIN
YXIM

(Bacillus
subtilis) 		PF13472
(Lipase_GDSL_2) 		4 ASP A  83
ILE A  30
ASN A  77
TYR A  38
 None
 1.24A 6a93B-2o14A:
undetectable		 6a93B-2o14A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rbd BH2358 PROTEIN

(Bacillus
halodurans) 		PF11553
(DUF3231) 		4 ASP A 109
PHE A  97
ASN A  29
TYR A  35
 None
 1.19A 6a93B-2rbdA:
2.3		 6a93B-2rbdA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uut RNA-DIRECTED RNA
POLYMERASE

(Sapporo virus) 		PF00680
(RdRP_1) 		4 ASP A 222
ILE A 398
ASN A 472
TYR A 443
 None
 1.20A 6a93B-2uutA:
undetectable		 6a93B-2uutA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsa MOSQUITOCIDAL TOXIN

(Lysinibacillus
sphaericus) 		PF05588
(Botulinum_HA-17)
PF14200
(RicinB_lectin_2) 		4 ASP A 677
ILE A 673
ASN A 598
TYR A 718
 None
 0.98A 6a93B-2vsaA:
undetectable		 6a93B-2vsaA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w9s DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003

(Staphylococcus
aureus) 		PF00186
(DHFR_1) 		4 ASP A 107
ILE A 102
PHE A 123
TYR A 109
 None
 1.17A 6a93B-2w9sA:
undetectable		 6a93B-2w9sA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xy4 ZINC ABC
TRANSPORTER,
PERIPLASMIC
ZINC-BINDING PROTEIN

(Salmonella
enterica) 		PF01297
(ZnuA) 		4 ASP A 192
ILE A 154
ASN A 305
TYR A 221
 None
 1.20A 6a93B-2xy4A:
undetectable		 6a93B-2xy4A:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y8n 4-HYDROXYPHENYLACETA
TE DECARBOXYLASE
LARGE SUBUNIT

(Clostridium
scatologenes) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		4 ASP A 138
ILE A 160
PHE A 390
ASN A 191
 None
 1.18A 6a93B-2y8nA:
3.5		 6a93B-2y8nA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zf5 GLYCEROL KINASE

(Thermococcus
kodakarensis) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ASP O 400
ILE O  18
PHE O  20
ASN O 268
 None
 1.24A 6a93B-2zf5O:
undetectable		 6a93B-2zf5O:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d4r DOMAIN OF UNKNOWN
FUNCTION FROM THE
PFAM-B_34464 FAMILY

(Methanococcus
maripaludis) 		PF09891
(DUF2118) 		4 ASP A  50
ILE A   3
PHE A  99
TYR A 146
 None
 1.20A 6a93B-3d4rA:
undetectable		 6a93B-3d4rA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dra PROTEIN
FARNESYLTRANSFERASE/
GERANYLGERANYLTRANSF
ERASE TYPE-1 SUBUNIT
ALPHA
GERANYLGERANYLTRANSF
ERASE TYPE I BETA
SUBUNIT

(Candida
albicans;
Candida
albicans) 		PF01239
(PPTA)
PF00432
(Prenyltrans) 		4 ASP B  28
ILE A  23
PHE B  61
TYR B  81
 None
 1.06A 6a93B-3draB:
undetectable		 6a93B-3draB:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3efa PUTATIVE
ACETYLTRANSFERASE

(Lactobacillus
plantarum) 		PF13673
(Acetyltransf_10) 		4 ASP A  39
ILE A  29
ASN A  11
TYR A  16
 None
 1.18A 6a93B-3efaA:
undetectable		 6a93B-3efaA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g25 GLYCEROL KINASE

(Staphylococcus
aureus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ASP A 408
ILE A  18
PHE A  20
ASN A 273
 None
 1.25A 6a93B-3g25A:
undetectable		 6a93B-3g25A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gxa OUTER MEMBRANE
LIPOPROTEIN GNA1946

(Neisseria
meningitidis) 		PF03180
(Lipoprotein_9) 		4 ASP A  53
ILE A  62
PHE A 264
TYR A 275
 None
 1.22A 6a93B-3gxaA:
undetectable		 6a93B-3gxaA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvn HEMOLYSIN

(Streptococcus
suis) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		4 ILE A  90
PHE A 320
ASN A 129
TYR A 270
 None
 1.25A 6a93B-3hvnA:
undetectable		 6a93B-3hvnA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvn HEMOLYSIN

(Streptococcus
suis) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		4 ILE A 206
PHE A 208
ASN A 375
TYR A 378
 None
 1.18A 6a93B-3hvnA:
undetectable		 6a93B-3hvnA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6s SUBTILISIN-LIKE
PROTEASE

(Solanum
lycopersicum) 		PF00082
(Peptidase_S8) 		4 ASP A 402
ILE A 414
ASN A 454
TYR A 375
 None
 1.13A 6a93B-3i6sA:
undetectable		 6a93B-3i6sA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihv SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ASP A 337
ILE A 347
ASN A 446
TYR A 453
 None
EDO  A   9 (-3.9A)
None
None
 1.24A 6a93B-3ihvA:
2.1		 6a93B-3ihvA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ir1 OUTER MEMBRANE
LIPOPROTEIN GNA1946

(Neisseria
meningitidis) 		PF03180
(Lipoprotein_9) 		4 ASP A  53
ILE A  62
PHE A 264
TYR A 275
 None
 1.21A 6a93B-3ir1A:
undetectable		 6a93B-3ir1A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jcm U4/U6 SMALL NUCLEAR
RIBONUCLEOPROTEIN
PRP4
U4/U6 SMALL NUCLEAR
RIBONUCLEOPROTEIN
PRP3

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF06544
(DUF1115)
PF08572
(PRP3) 		4 ASP B 335
ILE B 378
ASN B 126
TYR K 173
 None
 1.08A 6a93B-3jcmB:
undetectable		 6a93B-3jcmB:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lup DEGV FAMILY PROTEIN

(Streptococcus
agalactiae) 		PF02645
(DegV) 		4 ASP A 224
ILE A 217
PHE A 276
TYR A 227
 None
 1.00A 6a93B-3lupA:
undetectable		 6a93B-3lupA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m4p ASPARAGINYL-TRNA
SYNTHETASE, PUTATIVE

(Entamoeba
histolytica) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 ILE A 341
PHE A 252
ASN A 168
TYR A 419
 None
 1.22A 6a93B-3m4pA:
undetectable		 6a93B-3m4pA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nat UNCHARACTERIZED
PROTEIN

(Enterococcus
faecalis) 		PF11217
(DUF3013) 		4 ASP A 102
ILE A  88
PHE A  71
TYR A   9
 None
CIT  A 162 (-3.8A)
None
None
 1.09A 6a93B-3natA:
undetectable		 6a93B-3natA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o1h PERIPLASMIC PROTEIN
TORT

(Vibrio
parahaemolyticus) 		PF00532
(Peripla_BP_1) 		4 ASP B 272
ILE B 315
ASN B 202
TYR B  44
 None
None
None
TMO  B   1 (-3.7A)
 1.17A 6a93B-3o1hB:
undetectable		 6a93B-3o1hB:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o7q L-FUCOSE-PROTON
SYMPORTER

(Escherichia
coli) 		PF07690
(MFS_1) 		4 ILE A 127
PHE A 108
ASN A  60
TYR A 117
 None
 1.24A 6a93B-3o7qA:
undetectable		 6a93B-3o7qA:
22.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pbl D(3) DOPAMINE
RECEPTOR, LYSOZYME
CHIMERA

(Homo sapiens;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 ASP A 110
ILE A 118
PHE A 338
TYR A 373
 ETQ  A1200 (-3.5A)
None
None
ETQ  A1200 (-4.4A)
 0.46A 6a93B-3pblA:
33.4		 6a93B-3pblA:
30.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pds FUSION PROTEIN
BETA-2 ADRENERGIC
RECEPTOR/LYSOZYME

(Homo sapiens;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 ASP A 113
ILE A 121
PHE A 282
TYR A 316
 ERC  A1201 (-3.7A)
None
None
None
 0.64A 6a93B-3pdsA:
30.8		 6a93B-3pdsA:
30.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qpc CUTINASE

(Fusarium solani) 		PF01083
(Cutinase) 		4 ILE A 130
PHE A 102
ASN A  58
TYR A  38
 None
 1.05A 6a93B-3qpcA:
undetectable		 6a93B-3qpcA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ru8 EPITOPE SCAFFOLD
2BODX43

(Thermobifida
fusca;
Human
immunodeficiency
virus;
synthetic
construct) 		PF01341
(Glyco_hydro_6) 		4 ASP X 253
ILE X 246
ASN X 217
TYR X 179
 None
 1.02A 6a93B-3ru8X:
undetectable		 6a93B-3ru8X:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rze HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA

(Homo sapiens;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 ASP A 107
ILE A 115
PHE A 424
TYR A 458
 5EH  A1200 ( 2.6A)
D7V  A1201 (-3.8A)
None
5EH  A1200 ( 4.4A)
 0.48A 6a93B-3rzeA:
29.1		 6a93B-3rzeA:
28.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s25 HYPOTHETICAL
7-BLADED
BETA-PROPELLER-LIKE
PROTEIN

([Eubacterium]
rectale) 		PF16472
(DUF5050) 		4 ILE A 325
PHE A 306
ASN A 254
TYR A 267
 None
 1.05A 6a93B-3s25A:
undetectable		 6a93B-3s25A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3she MAP KINASE-ACTIVATED
PROTEIN KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		4 ASP A 149
ILE A 130
PHE A 138
ASN A 305
 None
 1.21A 6a93B-3sheA:
3.1		 6a93B-3sheA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u2p RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain) 		4 ILE A 379
PHE A 389
ASN A 470
TYR A 444
 None
None
NAG  A1005 (-1.8A)
None
 1.10A 6a93B-3u2pA:
undetectable		 6a93B-3u2pA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u7u RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV) 		4 ILE A 379
PHE A 389
ASN A 470
TYR A 444
 None
 1.25A 6a93B-3u7uA:
undetectable		 6a93B-3u7uA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3va6 TWO-COMPONENT SYSTEM
SENSOR HISTIDINE
KINASE

(Bacteroides
thetaiotaomicron) 		PF07494
(Reg_prop)
PF07495
(Y_Y_Y) 		4 ASP A 726
ILE A 768
ASN A 743
TYR A 741
 None
 1.19A 6a93B-3va6A:
undetectable		 6a93B-3va6A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wky PROPHENOLOXIDASE B

(Marsupenaeus
japonicus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 ILE A 554
PHE A 618
ASN A 402
TYR A 223
 None
 1.21A 6a93B-3wkyA:
undetectable		 6a93B-3wkyA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4arc LEUCINE--TRNA LIGASE

(Escherichia
coli) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2) 		4 ASP A 345
ILE A 232
PHE A 234
TYR A 258
 None
 1.16A 6a93B-4arcA:
2.3		 6a93B-4arcA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dkl MU-TYPE OPIOID
RECEPTOR, LYSOZYME
CHIMERA

(Mus musculus;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 ASP A 147
ILE A 155
PHE A 289
TYR A 326
 BF0  A 601 (-3.2A)
None
None
BF0  A 601 (-3.8A)
 0.54A 6a93B-4dklA:
28.6		 6a93B-4dklA:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ej4 DELTA-TYPE OPIOID
RECEPTOR, LYSOZYME
CHIMERA

(Mus musculus;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 ASP A 128
ILE A 136
PHE A 270
TYR A 308
 EJ4  A 500 (-3.0A)
None
None
EJ4  A 500 (-3.8A)
 0.63A 6a93B-4ej4A:
27.9		 6a93B-4ej4A:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eo4 THREONINE--TRNA
LIGASE,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon) 		4 ILE A 455
PHE A 392
ASN A 432
TYR A 417
 None
 1.18A 6a93B-4eo4A:
undetectable		 6a93B-4eo4A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eog PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF09455
(Cas_DxTHG) 		4 ILE A 331
PHE A 457
ASN A 432
TYR A 441
 None
None
ZN  A 502 ( 4.2A)
None
 1.17A 6a93B-4eogA:
undetectable		 6a93B-4eogA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN

(Salmonella
enterica) 		PF00497
(SBP_bac_3) 		4 ASP A  35
ILE A  86
PHE A  88
TYR A  92
 None
 1.25A 6a93B-4f3sA:
undetectable		 6a93B-4f3sA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fgc NADPH-DEPENDENT
7-CYANO-7-DEAZAGUANI
NE REDUCTASE

(Bacillus
subtilis) 		PF14489
(QueF) 		4 ASP A 106
ILE A  66
PHE A  51
TYR A  25
 None
 1.13A 6a93B-4fgcA:
undetectable		 6a93B-4fgcA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gbr BETA-2 ADRENERGIC
RECEPTOR

(Homo sapiens) 		PF00001
(7tm_1) 		4 ASP A 113
ILE A 121
PHE A 254
TYR A 288
 CAU  A 500 (-3.0A)
None
None
CAU  A 500 (-4.6A)
 0.59A 6a93B-4gbrA:
31.1		 6a93B-4gbrA:
29.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gis ENOLASE

(Vibrio harveyi) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 222
PHE A 218
ASN A 163
TYR A 157
 None
 1.17A 6a93B-4gisA:
undetectable		 6a93B-4gisA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h1s 5'-NUCLEOTIDASE

(Homo sapiens) 		PF00149
(Metallophos)
PF02872
(5_nucleotid_C) 		4 ASP A 226
ILE A  31
ASN A 117
TYR A 176
 None
None
ZN  A 602 ( 2.7A)
None
 1.19A 6a93B-4h1sA:
undetectable		 6a93B-4h1sA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsc STREPTOLYSIN O

(Streptococcus
pyogenes) 		PF01289
(Thiol_cytolysin)
PF17440
(Thiol_cytolys_C) 		4 ILE X 280
PHE X 282
ASN X 157
TYR X 452
 None
 1.15A 6a93B-4hscX:
undetectable		 6a93B-4hscX:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i1a RESPONSE REGULATOR
ASPARTATE
PHOSPHATASE I

(Bacillus
subtilis) 		PF13424
(TPR_12) 		4 ASP A 346
ILE A 307
PHE A 325
TYR A 361
 None
 1.24A 6a93B-4i1aA:
2.2		 6a93B-4i1aA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i99 CHROMOSOME PARTITION
PROTEIN SMC

(Pyrococcus
furiosus) 		PF02463
(SMC_N) 		4 ASP A 164
ILE A1085
PHE A1081
ASN A1043
 None
 1.16A 6a93B-4i99A:
undetectable		 6a93B-4i99A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4io6 AVGLUR1 LIGAND
BINDING DOMAIN

(Adineta vaga) 		PF00497
(SBP_bac_3) 		4 ASP A  85
ILE A 209
ASN A  64
TYR A  67
 MET  A 301 (-4.7A)
None
None
MET  A 301 (-3.1A)
 0.98A 6a93B-4io6A:
undetectable		 6a93B-4io6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kv7 PROBABLE
LEUCINE/ISOLEUCINE/V
ALINE-BINDING
PROTEIN

(Rhodopirellula
baltica) 		PF13458
(Peripla_BP_6) 		4 ASP A  99
ILE A 135
PHE A 145
ASN A  69
 None
 1.24A 6a93B-4kv7A:
undetectable		 6a93B-4kv7A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mmo SSO-CP2
METALLO-CARBOXYPETID
ASE

(Sulfolobus
solfataricus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ASP A 158
ILE A 161
PHE A 430
ASN A  61
 None
 1.25A 6a93B-4mmoA:
undetectable		 6a93B-4mmoA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ou2 2-AMINOMUCONATE
6-SEMIALDEHYDE
DEHYDROGENASE

(Pseudomonas
fluorescens) 		PF00171
(Aldedh) 		4 ASP A 396
PHE A 315
ASN A 273
TYR A 309
 None
 1.08A 6a93B-4ou2A:
undetectable		 6a93B-4ou2A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4owt INTEGRATOR COMPLEX
SUBUNIT 3

(Homo sapiens) 		PF10189
(Ints3) 		4 ASP A 117
ILE A 126
PHE A  94
ASN A  76
 None
 1.20A 6a93B-4owtA:
undetectable		 6a93B-4owtA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p5y GLYCOSYL HYDROLASE,
FAMILY
31/FIBRONECTIN TYPE
III DOMAIN PROTEIN

(Clostridium
perfringens) 		PF00754
(F5_F8_type_C) 		4 ILE A  63
PHE A 159
ASN A 108
TYR A  76
 None
 1.11A 6a93B-4p5yA:
undetectable		 6a93B-4p5yA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pd4 CYTOCHROME B

(Saccharomyces
cerevisiae) 		PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B) 		4 ILE C 147
PHE C 129
ASN C  57
TYR C 136
 AOQ  C4003 (-4.8A)
AOQ  C4003 (-4.6A)
None
None
 1.20A 6a93B-4pd4C:
5.1		 6a93B-4pd4C:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pp8 RETINOIC ACID
EARLY-INDUCIBLE
PROTEIN 1-BETA

(Mus musculus) 		PF14586
(MHC_I_2) 		4 ASP C 146
ILE C 139
PHE C 120
ASN C  67
 GOL  C 201 ( 4.7A)
None
None
None
 1.10A 6a93B-4pp8C:
undetectable		 6a93B-4pp8C:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qsl PYRUVATE CARBOXYLASE

(Listeria
monocytogenes) 		no annotation 4 ASP H  38
ILE H  17
ASN H  68
TYR H  63
 None
 1.20A 6a93B-4qslH:
undetectable		 6a93B-4qslH:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rml LATROPHILIN-3

(Mus musculus) 		PF02191
(OLF) 		4 ASP A 458
ILE A 407
PHE A 425
TYR A 211
 None
 1.22A 6a93B-4rmlA:
undetectable		 6a93B-4rmlA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rwa SOLUBLE CYTOCHROME
B562,DELTA-TYPE
OPIOID RECEPTOR

(Escherichia
coli;
Homo sapiens) 		PF00001
(7tm_1)
PF07361
(Cytochrom_B562) 		4 ASP A 128
ILE A 136
PHE A 270
TYR A 308
 None
 0.58A 6a93B-4rwaA:
28.0		 6a93B-4rwaA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3w 2-AMINOMUCONATE
6-SEMIALDEHYDE
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00171
(Aldedh) 		4 ASP A 391
PHE A 310
ASN A 268
TYR A 304
 None
 1.05A 6a93B-4u3wA:
undetectable		 6a93B-4u3wA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8i PEPTIDOGLYCAN
RECOGNITION PROTEIN
3

(Branchiostoma
belcheri) 		PF01510
(Amidase_2) 		4 ASP A 135
ILE A 177
ASN A 112
TYR A 139
 None
 0.91A 6a93B-4z8iA:
undetectable		 6a93B-4z8iA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zdv MICROTUBULE-ASSOCIAT
ED PROTEINS 1A/1B
LIGHT CHAIN 3A

(Homo sapiens) 		PF02991
(Atg8) 		4 ASP A 106
ILE A  23
ASN A  84
TYR A 110
 None
 0.93A 6a93B-4zdvA:
undetectable		 6a93B-4zdvA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zev PFHAD1

(Plasmodium
falciparum) 		PF08282
(Hydrolase_3) 		4 ASP A 104
ILE A  87
ASN A 108
TYR A 170
 None
 1.11A 6a93B-4zevA:
undetectable		 6a93B-4zevA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8q PUTATIVE RETAINING
B-GLYCOSIDASE

(Saccharophagus
degradans) 		PF00150
(Cellulase) 		4 ASP A 124
ILE A 106
PHE A 167
ASN A 177
 None
 1.10A 6a93B-5a8qA:
undetectable		 6a93B-5a8qA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ay9 4-O-BETA-D-MANNOSYL-
D-GLUCOSE
PHOSPHORYLASE

(Ruminococcus
albus) 		PF04041
(Glyco_hydro_130) 		4 ASP A 328
ILE A 335
ASN A  78
TYR A  81
 None
 1.11A 6a93B-5ay9A:
undetectable		 6a93B-5ay9A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5clw 1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME

(Homo sapiens) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		4 ASP A 286
ILE A 206
PHE A 551
TYR A 251
 None
 1.08A 6a93B-5clwA:
undetectable		 6a93B-5clwA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dst PROTEIN ARGININE
N-METHYLTRANSFERASE
8

(Homo sapiens) 		PF06325
(PrmA) 		4 ASP A  92
ILE A 124
PHE A 128
ASN A 312
 None
 1.18A 6a93B-5dstA:
undetectable		 6a93B-5dstA:
21.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5f8u BETA-1 ADRENERGIC
RECEPTOR

(Meleagris
gallopavo) 		no annotation 4 ASP B 121
ILE B 129
PHE B 299
TYR B 333
 P32  B 400 (-2.2A)
None
None
P32  B 400 (-4.6A)
 0.55A 6a93B-5f8uB:
31.1		 6a93B-5f8uB:
31.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gqr LEUCINE-RICH REPEAT
RECEPTOR-LIKE
PROTEIN KINASE TDR

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		4 ASP B 447
ILE B 457
PHE B 477
ASN B 403
 None
 1.22A 6a93B-5gqrB:
undetectable		 6a93B-5gqrB:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7w VENOM
5'-NUCLEOTIDASE

(Naja atra) 		no annotation 4 ASP A 226
ILE A  32
ASN A 117
TYR A 176
 None
None
ZN  A 606 (-2.6A)
None
 1.23A 6a93B-5h7wA:
undetectable		 6a93B-5h7wA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k59 UNCHARACTERIZED
LEUKOCIDIN-LIKE
PROTEIN 1

(Staphylococcus
aureus) 		no annotation 4 ASP B 101
ILE B  88
ASN B 141
TYR B 117
 None
 1.17A 6a93B-5k59B:
undetectable		 6a93B-5k59B:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k59 UNCHARACTERIZED
LEUKOCIDIN-LIKE
PROTEIN 1
UNCHARACTERIZED
LEUKOCIDIN-LIKE
PROTEIN 2

(Staphylococcus
aureus;
Staphylococcus
aureus) 		no annotation
no annotation 		4 ASP D  67
ILE D 169
ASN B 135
TYR D 165
 None
 1.15A 6a93B-5k59D:
undetectable		 6a93B-5k59D:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kd5 METALLOPEPTIDASE

(Bacteroides
thetaiotaomicron) 		PF13402
(Peptidase_M60)
PF17291
(M60-like_N) 		4 ASP A 505
ILE A 556
PHE A 484
ASN A 527
 None
 1.21A 6a93B-5kd5A:
undetectable		 6a93B-5kd5A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzl HEME OXYGENASE

(Leptospira
interrogans) 		PF01126
(Heme_oxygenase) 		4 ILE A 160
PHE A 166
ASN A  58
TYR A  68
 None
 1.10A 6a93B-5kzlA:
undetectable		 6a93B-5kzlA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l1x HMPV F1 SUBUNIT

(Human
metapneumovirus) 		PF00523
(Fusion_gly) 		4 ASP B 306
ILE B 352
ASN B 342
TYR B 310
 None
 1.24A 6a93B-5l1xB:
undetectable		 6a93B-5l1xB:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lsk PROTEIN MIS12
HOMOLOG
POLYAMINE-MODULATED
FACTOR 1

(Homo sapiens;
Homo sapiens) 		PF05859
(Mis12)
PF03980
(Nnf1) 		4 ASP B  39
ILE B  88
PHE A  28
ASN B 100
 None
 1.24A 6a93B-5lskB:
undetectable		 6a93B-5lskB:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5td8 KINETOCHORE PROTEIN
SPC24
KINETOCHORE PROTEIN
SPC25

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF08286
(Spc24)
no annotation 		4 ILE D 171
PHE D 209
ASN C  60
TYR C 165
 None
 1.25A 6a93B-5td8D:
undetectable		 6a93B-5td8D:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1s SEPARIN

(Saccharomyces
cerevisiae) 		PF03568
(Peptidase_C50) 		4 ILE A 596
PHE A 641
ASN A 653
TYR A 648
 None
 1.19A 6a93B-5u1sA:
undetectable		 6a93B-5u1sA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udg NADPH-DEPENDENT
7-CYANO-7-DEAZAGUANI
NE REDUCTASE

(Bacillus
subtilis) 		PF14489
(QueF) 		4 ASP A 106
ILE A  66
PHE A  51
TYR A  25
 MG  A 202 (-3.3A)
None
None
None
 1.11A 6a93B-5udgA:
undetectable		 6a93B-5udgA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w1j THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Echinococcus
granulosus) 		no annotation 4 ASP A 111
ILE A  43
ASN A  13
TYR A 456
 None
 1.04A 6a93B-5w1jA:
undetectable		 6a93B-5w1jA:
21.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5wiv D(4) DOPAMINE
RECEPTOR, SOLUBLE
CYTOCHROME B562
CHIMERA

(Escherichia
coli;
Homo sapiens) 		no annotation 4 ASP A 115
ILE A 123
PHE A 403
TYR A 438
 AQD  A1201 (-3.3A)
None
None
None
 0.41A 6a93B-5wivA:
34.7		 6a93B-5wivA:
44.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlh LBACAS13A H328A
(C2C2)

(Lachnospiraceae
bacterium
NK4A179) 		no annotation 4 ILE A 855
PHE A 721
ASN A 709
TYR A 714
 None
 1.18A 6a93B-5wlhA:
undetectable		 6a93B-5wlhA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wtk CRISPR-ASSOCIATED
ENDORIBONUCLEASE
C2C2

(Leptotrichia
shahii) 		no annotation 4 ASP A1301
ILE A1286
ASN A1314
TYR A1318
 None
None
C  B   2 ( 4.5A)
None
 1.21A 6a93B-5wtkA:
4.5		 6a93B-5wtkA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x49 PROBABLE XAA-PRO
AMINOPEPTIDASE 3

(Homo sapiens) 		PF00557
(Peptidase_M24)
PF05195
(AMP_N) 		4 ILE A 343
PHE A 266
ASN A 319
TYR A 283
 None
 1.15A 6a93B-5x49A:
undetectable		 6a93B-5x49A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xei CHROMOSOME PARTITION
PROTEIN SMC

(Pyrococcus
yayanosii) 		PF02463
(SMC_N) 		4 ASP A 164
ILE A1085
PHE A1081
ASN A1043
 None
 1.17A 6a93B-5xeiA:
undetectable		 6a93B-5xeiA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsq NUCLEOPROTEIN

(Marburg
marburgvirus) 		PF05505
(Ebola_NP) 		4 ASP A  34
ILE A  22
PHE A  83
TYR A  93
 None
 1.21A 6a93B-5xsqA:
undetectable		 6a93B-5xsqA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xzu BETA-XYLANASE

(Bispora sp.
MEY-1) 		no annotation 4 ASP A 290
ILE A  50
ASN A  38
TYR A  32
 None
 0.91A 6a93B-5xzuA:
undetectable		 6a93B-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yvf -

(-) 		no annotation 4 ILE A 232
PHE A  77
ASN A 108
TYR A 135
 None
 1.24A 6a93B-5yvfA:
undetectable		 6a93B-5yvfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bqh 5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562

(Escherichia
coli;
Homo sapiens) 		no annotation 5 ASP A 134
ILE A 142
PHE A 320
ASN A 351
TYR A 358
 E2J  A1201 (-3.0A)
E2J  A1201 (-3.5A)
E2J  A1201 (-4.4A)
E2J  A1201 (-3.8A)
None
 0.47A 6a93B-6bqhA:
37.6		 6a93B-6bqhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0t CGMP-DEPENDENT
PROTEIN KINASE 1

(Homo sapiens) 		no annotation 4 ASP A 597
ILE A 591
PHE A 579
ASN A 568
 None
 1.03A 6a93B-6c0tA:
2.4		 6a93B-6c0tA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6e4e -

(-) 		no annotation 4 ASP A 107
ILE A 102
PHE A 123
TYR A 109
 None
 1.19A 6a93B-6e4eA:
undetectable		 6a93B-6e4eA:
undetectable