SIMILAR PATTERNS OF AMINO ACIDS FOR 6A7P_B_9SCB601_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8g PROTEIN
(1-AMINOCYCLOPROPANE
-1-CARBOXYLATE
SYNTHASE)

(Malus domestica) 		PF00155
(Aminotran_1_2) 		4 ASN A 124
PHE A 148
TYR A 233
SER A 270
 PLP  A 500 ( 4.2A)
None
PLP  A 500 ( 4.4A)
PLP  A 500 ( 2.6A)
 1.46A 6a7pB-1b8gA:
0.0		 6a7pB-1b8gA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c0n PROTEIN (CSDB
PROTEIN)

(Escherichia
coli) 		PF00266
(Aminotran_5) 		4 PHE A   3
TYR A 228
LEU A  15
SER A  29
 None
 1.24A 6a7pB-1c0nA:
undetectable		 6a7pB-1c0nA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hno D3,D2-ENOYL COA
ISOMERASE ECI1

(Saccharomyces
cerevisiae) 		PF00378
(ECH_1) 		4 CYH A 190
PHE A 169
TYR A 148
LEU A 119
 None
 1.49A 6a7pB-1hnoA:
0.0		 6a7pB-1hnoA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j93 UROPORPHYRINOGEN
DECARBOXYLASE

(Nicotiana
tabacum) 		PF01208
(URO-D) 		4 PHE A 120
TYR A 128
LEU A  79
SER A  55
 None
 1.50A 6a7pB-1j93A:
undetectable		 6a7pB-1j93A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qe0 HISTIDINE--TRNA
LIGASE

(Staphylococcus
aureus) 		PF03129
(HGTP_anticodon)
PF13393
(tRNA-synt_His) 		4 PHE A 306
TYR A 151
LEU A  26
SER A 153
 None
 1.47A 6a7pB-1qe0A:
undetectable		 6a7pB-1qe0A:
21.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		5 ASN A 391
PHE A 403
TYR A 411
LEU A 453
SER A 489
 None
 1.16A 6a7pB-1tf0A:
47.9		 6a7pB-1tf0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ua7 ALPHA-AMYLASE

(Bacillus
subtilis) 		PF00128
(Alpha-amylase) 		4 ASN A 364
PHE A 362
TYR A 231
SER A 299
 None
 1.27A 6a7pB-1ua7A:
0.7		 6a7pB-1ua7A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xup GLYCEROL KINASE

(Enterococcus
casseliflavus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 PHE O 271
TYR O 136
LEU O 131
SER O 138
 GOL  O 500 ( 4.8A)
None
None
None
 1.23A 6a7pB-1xupO:
undetectable		 6a7pB-1xupO:
21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ysx SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		4 ASN A 391
CYH A 392
PHE A 403
TYR A 411
 4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-3.3A)
 0.84A 6a7pB-1ysxA:
14.1		 6a7pB-1ysxA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zj9 PROBABLE
FERREDOXIN-DEPENDENT
NITRITE REDUCTASE
NIRA

(Mycobacterium
tuberculosis) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 PHE A 227
TYR A 208
LEU A 307
SER A 275
 None
 1.28A 6a7pB-1zj9A:
undetectable		 6a7pB-1zj9A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d7s RNA-DEPENDENT RNA
POLYMERASE

(Foot-and-mouth
disease virus) 		PF00680
(RdRP_1) 		4 PHE A 261
TYR A  81
LEU A  89
SER A 213
 None
 1.17A 6a7pB-2d7sA:
undetectable		 6a7pB-2d7sA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dd7 GREEN FLUORESCENT
PROTEIN

(Chiridius
poppei) 		PF01353
(GFP) 		4 ASN A  15
PHE A 126
TYR A 164
LEU A  95
 None
 1.28A 6a7pB-2dd7A:
undetectable		 6a7pB-2dd7A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jm1 TRANSCRIPTIONAL
REGULATOR ATRX

(Homo sapiens) 		no annotation 4 ASN A 237
CYH A 232
PHE A 239
TYR A 204
 None
ZN  A   3 (-2.3A)
None
None
 1.30A 6a7pB-2jm1A:
undetectable		 6a7pB-2jm1A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q50 GLYOXYLATE
REDUCTASE/HYDROXYPYR
UVATE REDUCTASE

(Homo sapiens) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ASN A 250
PHE A 231
LEU A 282
SER A 272
 None
 1.45A 6a7pB-2q50A:
undetectable		 6a7pB-2q50A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a8u OMEGA-AMINO
ACID--PYRUVATE
AMINOTRANSFERASE

(Pseudomonas
putida) 		PF00202
(Aminotran_3) 		4 ASN X 427
TYR X  53
LEU X 382
SER X  57
 None
 0.98A 6a7pB-3a8uX:
undetectable		 6a7pB-3a8uX:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahi XYLULOSE
5-PHOSPHATE/FRUCTOSE
6-PHOSPHATE
PHOSPHOKETOLASE

(Bifidobacterium
breve) 		PF03894
(XFP)
PF09363
(XFP_C)
PF09364
(XFP_N) 		4 PHE A 236
TYR A 242
LEU A 190
SER A 196
 None
 1.47A 6a7pB-3ahiA:
undetectable		 6a7pB-3ahiA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ai7 XYLULOSE-5-PHOSPHATE
/FRUCTOSE-6-PHOSPHAT
E PHOSPHOKETOLASE

(Bifidobacterium
longum) 		PF03894
(XFP)
PF09363
(XFP_C)
PF09364
(XFP_N) 		4 PHE A 236
TYR A 242
LEU A 190
SER A 196
 None
 1.48A 6a7pB-3ai7A:
undetectable		 6a7pB-3ai7A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2d CD180 ANTIGEN

(Homo sapiens) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		4 ASN A 490
PHE A 481
LEU A 501
SER A 539
 None
 1.44A 6a7pB-3b2dA:
undetectable		 6a7pB-3b2dA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE

(Corynebacterium
diphtheriae) 		no annotation 4 ASN A 123
PHE A  96
LEU A 133
SER A 145
 None
 1.36A 6a7pB-3hm2A:
undetectable		 6a7pB-3hm2A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hzs MONOFUNCTIONAL
GLYCOSYLTRANSFERASE

(Staphylococcus
aureus) 		PF00912
(Transgly) 		4 ASN A 268
TYR A 260
LEU A 214
SER A 243
 None
 1.40A 6a7pB-3hzsA:
undetectable		 6a7pB-3hzsA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iac GLUCURONATE
ISOMERASE

(Salmonella
enterica) 		PF02614
(UxaC) 		4 CYH A 459
PHE A 427
LEU A 435
SER A 400
 None
 1.20A 6a7pB-3iacA:
undetectable		 6a7pB-3iacA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jaf GLYCINE RECEPTOR
SUBUNIT ALPHAZ1

(Danio rerio) 		PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb) 		4 PHE A 203
TYR A 239
LEU A 158
SER A 289
 None
 1.10A 6a7pB-3jafA:
2.1		 6a7pB-3jafA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
PPI1

(Schizosaccharomyces
pombe) 		PF01423
(LSM) 		4 CYH d 129
PHE d  43
TYR d  38
LEU d  88
 None
 1.49A 6a7pB-3jb9d:
undetectable		 6a7pB-3jb9d:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jby V(D)J
RECOMBINATION-ACTIVA
TING PROTEIN 1

(Danio rerio) 		PF12940
(RAG1) 		4 ASN A 822
PHE A 826
TYR A 950
LEU A 962
 None
 1.30A 6a7pB-3jbyA:
undetectable		 6a7pB-3jbyA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jr1 PUTATIVE
FRUCTOSAMINE-3-KINAS
E

(Histophilus
somni) 		PF03881
(Fructosamin_kin) 		4 ASN A 138
PHE A 147
TYR A 260
LEU A 191
 None
 1.46A 6a7pB-3jr1A:
undetectable		 6a7pB-3jr1A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mfq HIGH-AFFINITY ZINC
UPTAKE SYSTEM
PROTEIN ZNUA

(Streptococcus
suis) 		PF01297
(ZnuA) 		4 ASN A 300
PHE A 134
LEU A 283
SER A 247
 None
 1.13A 6a7pB-3mfqA:
undetectable		 6a7pB-3mfqA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nzt GLUTAMATE--CYSTEINE
LIGASE

(Francisella
tularensis) 		PF04262
(Glu_cys_ligase) 		4 ASN A 278
TYR A 239
LEU A 274
SER A 282
 SO4  A 508 ( 3.4A)
None
None
None
 1.47A 6a7pB-3nztA:
undetectable		 6a7pB-3nztA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmk NUCLEOCAPSID PROTEIN

(Recombinant
vesicular
stomatitis
Indiana virus
rVSV-G/GFP) 		PF00945
(Rhabdo_ncap) 		4 ASN A 294
TYR A  27
LEU A 228
SER A 287
 None
 1.39A 6a7pB-3pmkA:
undetectable		 6a7pB-3pmkA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pss QNR

(Aeromonas
hydrophila) 		PF00805
(Pentapeptide)
PF13599
(Pentapeptide_4) 		4 CYH A  91
PHE A 123
LEU A  86
SER A  81
 None
 1.49A 6a7pB-3pssA:
undetectable		 6a7pB-3pssA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akk NITRATE REGULATORY
PROTEIN

(Klebsiella
oxytoca) 		PF03861
(ANTAR)
PF08376
(NIT) 		4 CYH A 226
PHE A 207
LEU A 273
SER A  40
 None
 1.23A 6a7pB-4akkA:
undetectable		 6a7pB-4akkA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b98 BETA-ALANINE--PYRUVA
TE TRANSAMINASE

(Pseudomonas
aeruginosa) 		PF00202
(Aminotran_3) 		4 ASN A 427
TYR A  54
LEU A 382
SER A  58
 None
 1.07A 6a7pB-4b98A:
undetectable		 6a7pB-4b98A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eme M18 ASPARTYL
AMINOPEPTIDASE

(Plasmodium
falciparum) 		PF02127
(Peptidase_M18) 		4 ASN A  64
CYH A  59
PHE A 398
SER A 386
 None
 1.49A 6a7pB-4emeA:
undetectable		 6a7pB-4emeA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hr3 PUTATIVE ACYL-COA
DEHYDROGENASE

(Mycobacteroides
abscessus) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 ASN A 105
PHE A  72
LEU A 130
SER A 140
 None
 1.46A 6a7pB-4hr3A:
undetectable		 6a7pB-4hr3A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m46 LUCIFERASE

(Lampyris
turkestanicus) 		PF00501
(AMP-binding) 		4 ASN A 229
CYH A 222
PHE A 260
LEU A 286
 None
 1.42A 6a7pB-4m46A:
undetectable		 6a7pB-4m46A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nz0 GENOME POLYPROTEIN

(Cardiovirus A) 		PF00680
(RdRP_1) 		4 PHE A 256
TYR A  75
LEU A  83
SER A 208
 None
 1.22A 6a7pB-4nz0A:
undetectable		 6a7pB-4nz0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pev MEMBRANE LIPOPROTEIN
FAMILY PROTEIN

(Aeropyrum
pernix) 		PF02608
(Bmp) 		4 ASN A 176
PHE A 342
LEU A 151
SER A 132
 None
 1.07A 6a7pB-4pevA:
undetectable		 6a7pB-4pevA:
22.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus) 		PF00273
(Serum_albumin) 		4 ASN A 391
PHE A 403
LEU A 453
SER A 489
 NPS  A 601 (-4.3A)
None
NPS  A 601 (-4.7A)
NPS  A 601 (-3.1A)
 0.93A 6a7pB-4po0A:
45.4		 6a7pB-4po0A:
74.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus) 		PF00273
(Serum_albumin) 		4 ASN A 391
TYR A 411
LEU A 453
SER A 489
 NPS  A 601 (-4.3A)
NPS  A 601 (-4.3A)
NPS  A 601 (-4.7A)
NPS  A 601 (-3.1A)
 0.86A 6a7pB-4po0A:
45.4		 6a7pB-4po0A:
74.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uhm OMEGA AMINO
ACID-PYRUVATE
AMINOTRANSFERASE

(Pseudomonas sp.) 		PF00202
(Aminotran_3) 		4 ASN A 427
TYR A  54
LEU A 382
SER A  58
 None
 1.10A 6a7pB-4uhmA:
undetectable		 6a7pB-4uhmA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zi6 CYTOSOL
AMINOPEPTIDASE

(Helicobacter
pylori) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 CYH A  75
TYR A 166
LEU A 174
SER A 401
 None
 1.41A 6a7pB-4zi6A:
undetectable		 6a7pB-4zi6A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c98 AGAP007691-PB

(Anopheles
gambiae) 		PF00079
(Serpin) 		4 CYH A 233
PHE A 357
LEU A 278
SER A 247
 None
 1.26A 6a7pB-5c98A:
undetectable		 6a7pB-5c98A:
21.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		4 ASN A 390
PHE A 402
LEU A 452
SER A 488
 None
 1.29A 6a7pB-5dqfA:
45.2		 6a7pB-5dqfA:
76.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		5 ASN A 391
PHE A 403
TYR A 411
LEU A 453
SER A 489
 None
 1.18A 6a7pB-5ghkA:
44.7		 6a7pB-5ghkA:
79.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens) 		PF11386
(VERL)
PF13416
(SBP_bac_8) 		4 ASN A4318
TYR A4310
LEU A4422
SER A4440
 None
 1.41A 6a7pB-5iicA:
1.3		 6a7pB-5iicA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksw DIHYDROOROTATE
DEHYDROGENASE

(Lactococcus
lactis) 		PF01180
(DHO_dh) 		4 ASN A 104
TYR A 113
LEU A  76
SER A 134
 FMN  A 401 (-2.9A)
None
FMN  A 401 (-4.5A)
None
 1.48A 6a7pB-5kswA:
undetectable		 6a7pB-5kswA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4

(Homo sapiens) 		no annotation 4 ASN A  26
PHE A  31
LEU A 409
SER A 405
 ASN  A  26 ( 0.6A)
PHE  A  31 ( 1.3A)
LEU  A 409 ( 0.5A)
SER  A 405 ( 0.0A)
 1.25A 6a7pB-5nksA:
undetectable		 6a7pB-5nksA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqr CONDENSIN COMPLEX
SUBUNIT 3

(Schizosaccharomyces
pombe) 		no annotation 4 ASN A 507
CYH A 503
PHE A 419
LEU A 371
 None
 1.44A 6a7pB-5oqrA:
undetectable		 6a7pB-5oqrA:
22.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus) 		no annotation 5 ASN A 390
PHE A 402
TYR A 410
LEU A 452
SER A 488
 None
 1.17A 6a7pB-5oriA:
44.3		 6a7pB-5oriA:
74.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uqc DIHYDROPYRIMIDINASE-
RELATED PROTEIN 2

(Mus musculus) 		PF01979
(Amidohydro_1) 		4 ASN A  26
PHE A  31
LEU A 409
SER A 405
 None
 1.35A 6a7pB-5uqcA:
undetectable		 6a7pB-5uqcA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w19 TRYPTOPHANASE

(Proteus
vulgaris) 		no annotation 4 ASN A 194
CYH A 193
PHE A 356
LEU A 395
 9TD  A 502 (-3.4A)
None
None
None
 1.10A 6a7pB-5w19A:
undetectable		 6a7pB-5w19A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjy ATP-BINDING CASSETTE
SUB-FAMILY A MEMBER
1

(Homo sapiens) 		PF00005
(ABC_tran)
PF12698
(ABC2_membrane_3) 		4 ASN A1709
CYH A1708
PHE A1672
SER A1343
 None
 1.27A 6a7pB-5xjyA:
undetectable		 6a7pB-5xjyA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yfg RAN GUANINE
NUCLEOTIDE RELEASE
FACTOR

(Homo sapiens) 		no annotation 4 ASN A  34
PHE A  10
TYR A 134
LEU A 138
 None
 1.37A 6a7pB-5yfgA:
undetectable		 6a7pB-5yfgA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus) 		no annotation 5 ASN A 391
PHE A 403
TYR A 411
LEU A 453
SER A 489
 None
 1.07A 6a7pB-5yxeA:
45.0		 6a7pB-5yxeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6coy CHLORIDE CHANNEL
PROTEIN 1

(Homo sapiens) 		no annotation 4 CYH A 277
PHE A 279
LEU A 219
SER A 139
 None
 1.42A 6a7pB-6coyA:
undetectable		 6a7pB-6coyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dbr -

(-) 		no annotation 4 ASN A 822
PHE A 826
TYR A 950
LEU A 962
 None
 1.37A 6a7pB-6dbrA:
undetectable		 6a7pB-6dbrA:
undetectable