SIMILAR PATTERNS OF AMINO ACIDS FOR 6A60_D_9CRD501
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ajz | DIHYDROPTEROATESYNTHASE (Escherichiacoli) |
PF00809(Pterin_bind) | 5 | ILE A 254ALA A 246ALA A 251LEU A 214ILE A 54 | None | 1.06A | 6a60D-1ajzA:undetectable | 6a60D-1ajzA:14.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g3n | V-CYCLIN (Humangammaherpesvirus8) |
PF00134(Cyclin_N)PF09080(K-cyclin_vir_C) | 5 | ALA C 200ALA C 199LEU C 228ALA C 238LEU C 162 | None | 1.00A | 6a60D-1g3nC:undetectable | 6a60D-1g3nC:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) |
PF00104(Hormone_recep) | 5 | LEU A 322ILE A 385CYH A 472HIS A 475LEU A 476 | LPP A 1 ( 4.8A)NoneLPP A 1 ( 4.2A)NoneLPP A 1 (-4.2A) | 0.55A | 6a60D-1hg4A:24.7 | 6a60D-1hg4A:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j0h | NEOPULLULANASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 5 | ILE A 428ALA A 388LEU A 441ILE A 455LEU A 486 | None | 0.99A | 6a60D-1j0hA:undetectable | 6a60D-1j0hA:7.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m3s | HYPOTHETICAL PROTEINYCKF (Bacillussubtilis) |
PF01380(SIS) | 5 | ILE A 39ALA A 55ILE A 107HIS A 32LEU A 29 | None | 1.01A | 6a60D-1m3sA:undetectable | 6a60D-1m3sA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mu2 | HIV-2 RT (Humanimmunodeficiencyvirus 2) |
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb) | 5 | ALA A 268ALA A 267GLN A 269ILE A 257LEU A 246 | None | 1.01A | 6a60D-1mu2A:undetectable | 6a60D-1mu2A:10.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nmo | HYPOTHETICAL PROTEINYBGI (Escherichiacoli) |
PF01784(NIF3) | 6 | ILE A 179ALA A 182ALA A 183ALA A 169ILE A 200HIS A 201 | None | 0.79A | 6a60D-1nmoA:undetectable | 6a60D-1nmoA:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o9j | ALDEHYDEDEHYDROGENASE,CYTOSOLIC 1 (Elephantulusedwardii) |
PF00171(Aldedh) | 5 | ALA A 170LEU A 174ALA A 194ILE A 95CYH A 125 | NoneNoneNAD A1501 (-4.1A)NoneNone | 1.01A | 6a60D-1o9jA:undetectable | 6a60D-1o9jA:11.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1on0 | YYCN PROTEIN (Bacillussubtilis) |
PF00583(Acetyltransf_1) | 5 | ILE A 3ALA A 112LEU A 76ALA A 116LEU A 96 | NoneNoneNoneNoneSO4 A 401 (-4.8A) | 1.03A | 6a60D-1on0A:undetectable | 6a60D-1on0A:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ort | ORNITHINETRANSCARBAMOYLASE (Pseudomonasaeruginosa) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | ILE A 324ALA A 66ALA A 67GLN A 70LEU A 50 | None | 1.04A | 6a60D-1ortA:undetectable | 6a60D-1ortA:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1psz | PROTEIN (SURFACEANTIGEN PSAA) (Streptococcuspneumoniae) |
PF01297(ZnuA) | 5 | ILE A 42GLN A 157LEU A 84ILE A 59LEU A 56 | None | 1.05A | 6a60D-1pszA:undetectable | 6a60D-1pszA:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pto | PERTUSSIS TOXIN(SUBUNIT S5) (Bordetellapertussis) |
PF09276(Pertus-S5-tox) | 5 | ILE F 70ALA F 60LEU F 15ALA F 65LEU F 86 | None | 0.99A | 6a60D-1ptoF:undetectable | 6a60D-1ptoF:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tt4 | PUTATIVE CYTOPLASMICPROTEIN (Salmonellaenterica) |
PF04107(GCS2) | 5 | ILE A 83ALA A 86ALA A 87LEU A 92ALA A 40 | None | 0.99A | 6a60D-1tt4A:undetectable | 6a60D-1tt4A:12.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ub7 | 3-OXOACYL-[ACYL-CARRIER PROTEIN]SYNTHASE (Thermusthermophilus) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | ALA A 6LEU A 133ALA A 68HIS A 121LEU A 117 | NoneNoneNoneGOL A 402 ( 4.6A)None | 1.03A | 6a60D-1ub7A:undetectable | 6a60D-1ub7A:15.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uhl | RETINOIC ACIDRECEPTOR RXR-BETA (Homo sapiens) |
PF00104(Hormone_recep) | 12 | ILE A 339ALA A 342ALA A 343GLN A 346LEU A 380PHE A 384ARG A 387ALA A 398ILE A 416CYH A 503HIS A 506LEU A 507 | MEI A1001 (-3.8A)MEI A1001 (-3.1A)MEI A1001 (-3.3A)NoneMEI A1001 (-3.8A)MEI A1001 (-4.5A)MEI A1001 (-3.6A)MEI A1001 (-3.4A)NoneMEI A1001 (-4.0A)NoneMEI A1001 (-4.6A) | 0.65A | 6a60D-1uhlA:35.6 | 6a60D-1uhlA:79.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vhe | AMINOPEPTIDASE/GLUCANASE HOMOLOG (Bacillussubtilis) |
PF05343(Peptidase_M42) | 5 | ALA A 283ALA A 286ILE A 358HIS A 272LEU A 315 | None | 0.96A | 6a60D-1vheA:undetectable | 6a60D-1vheA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vkx | PROTEIN (NF-KAPPA BP50 SUBUNIT) (Mus musculus) |
PF00554(RHD_DNA_bind)PF16179(RHD_dimer) | 5 | ILE B 494ALA B 497ALA B 498GLN B 501LEU B 451 | None | 1.05A | 6a60D-1vkxB:undetectable | 6a60D-1vkxB:14.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xiu | RXR-LIKE PROTEIN (Biomphalariaglabrata) |
PF00104(Hormone_recep) | 12 | ILE A 242ALA A 245ALA A 246GLN A 249LEU A 283PHE A 287ARG A 290ALA A 301ILE A 319CYH A 406HIS A 409LEU A 410 | 9CR A 201 ( 4.4A)9CR A 201 (-3.6A)9CR A 201 (-3.6A)9CR A 201 (-4.1A)9CR A 201 ( 4.1A)9CR A 201 (-4.7A)9CR A 201 (-2.8A)9CR A 201 (-3.4A)None9CR A 201 (-3.6A)9CR A 201 (-4.8A)9CR A 201 ( 4.8A) | 0.35A | 6a60D-1xiuA:32.3 | 6a60D-1xiuA:75.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xls | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 12 | ILE A 268ALA A 271ALA A 272GLN A 275LEU A 309PHE A 313ARG A 316ALA A 327ILE A 345CYH A 432HIS A 435LEU A 436 | 9CR A 801 (-3.9A)9CR A 801 (-3.6A)9CR A 801 (-3.5A)9CR A 801 (-4.7A)9CR A 801 (-4.2A)9CR A 801 (-4.3A)9CR A 801 (-2.6A)9CR A 801 (-3.3A)9CR A 801 ( 4.5A)9CR A 801 ( 3.7A)None9CR A 801 (-4.7A) | 0.40A | 6a60D-1xlsA:35.0 | 6a60D-1xlsA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zk7 | MERCURIC REDUCTASE (Pseudomonasaeruginosa) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 452ALA A 451GLN A 453ALA A 435ILE A 418 | NoneNoneGOL A3003 ( 3.8A)NoneNone | 1.01A | 6a60D-1zk7A:undetectable | 6a60D-1zk7A:11.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zkj | EXTENDED-SPECTRUMBETA-LACTAMASE (Klebsiellaaerogenes) |
PF00144(Beta-lactamase) | 5 | ALA A 163ALA A 164LEU A 174ALA A 78ILE A 225 | None | 0.84A | 6a60D-1zkjA:undetectable | 6a60D-1zkjA:12.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dpn | GLYCEROL KINASE (Thermusthermophilus) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | ALA A 57ALA A 58LEU A 5ALA A 29LEU A 171 | None | 0.85A | 6a60D-2dpnA:undetectable | 6a60D-2dpnA:9.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fow | RIBOSOMAL PROTEINL11 (Geobacillusstearothermophilus) |
PF00298(Ribosomal_L11) | 5 | ILE A 56ALA A 58ALA A 59LEU A 51ALA A 54 | None | 1.06A | 6a60D-2fowA:undetectable | 6a60D-2fowA:17.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gl8 | RETINOIC ACIDRECEPTOR RXR-GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 88PHE A 92ARG A 95ALA A 106ILE A 124CYH A 211 | None | 0.67A | 6a60D-2gl8A:28.0 | 6a60D-2gl8A:77.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hg4 | 6-DEOXYERYTHRONOLIDEB SYNTHASE (Saccharopolysporaerythraea) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF08990(Docking)PF16197(KAsynt_C_assoc) | 5 | ILE A 41ALA A 42ALA A 277HIS A 207LEU A 206 | None | 1.02A | 6a60D-2hg4A:undetectable | 6a60D-2hg4A:7.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ntb | PECTINESTERASE A (Dickeyadadantii) |
PF01095(Pectinesterase) | 5 | ILE A 45ALA A 48LEU A 79ALA A 30ILE A 129 | None | 0.88A | 6a60D-2ntbA:undetectable | 6a60D-2ntbA:14.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2nxx | ULTRASPIRACLE (USP,NR2B4) (Triboliumcastaneum) |
PF00104(Hormone_recep) | 5 | LEU A 255PHE A 259ARG A 262ALA A 273CYH A 378 | None | 0.97A | 6a60D-2nxxA:25.1 | 6a60D-2nxxA:52.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p8j | S-ADENOSYLMETHIONINE-DEPENDENTMETHYLTRANSFERASE (Clostridiumacetobutylicum) |
PF08241(Methyltransf_11) | 6 | ILE A 125ALA A 200ALA A 123LEU A 117ILE A 79CYH A 29 | NoneNoneNoneNoneGOL A 213 ( 4.6A)None | 1.35A | 6a60D-2p8jA:undetectable | 6a60D-2p8jA:13.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ptz | ENOLASE (Trypanosomabrucei) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | ILE A 116ALA A 119ALA A 120LEU A 83LEU A 135 | None | 0.89A | 6a60D-2ptzA:undetectable | 6a60D-2ptzA:12.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pzi | PROBABLESERINE/THREONINE-PROTEIN KINASE PKNG (Mycobacteriumtuberculosis) |
PF00069(Pkinase)PF16918(PknG_TPR)PF16919(PknG_rubred) | 5 | ILE A 661ALA A 664ALA A 665LEU A 704ALA A 644 | None | 0.99A | 6a60D-2pziA:undetectable | 6a60D-2pziA:8.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q60 | RETINOID X RECEPTOR (Polyandrocarpamisakiensis) |
PF00104(Hormone_recep) | 6 | LEU A 184PHE A 188ARG A 191ALA A 202ILE A 220CYH A 307 | None | 0.71A | 6a60D-2q60A:27.0 | 6a60D-2q60A:54.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ql2 | TRANSCRIPTION FACTORE2-ALPHANEUROGENICDIFFERENTIATIONFACTOR 1 (Mus musculus;Mus musculus) |
PF00010(HLH)PF00010(HLH) | 5 | LEU A 583ILE B 150CYH A 569HIS A 572LEU A 573 | None | 1.02A | 6a60D-2ql2A:undetectable | 6a60D-2ql2A:25.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qz6 | BETA-LACTAMASE (Pseudomonasfluorescens) |
PF00144(Beta-lactamase) | 5 | ALA A 162ALA A 163LEU A 173ALA A 77ILE A 224 | None | 0.91A | 6a60D-2qz6A:undetectable | 6a60D-2qz6A:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w3g | TWO COMPONENT SENSORHISTIDINE KINASEDEVS (GAF FAMILYPROTEIN) (Mycobacteriumtuberculosis) |
PF13185(GAF_2) | 6 | ALA A 194ALA A 196LEU A 170ALA A 191ILE A 125HIS A 93 | None | 1.44A | 6a60D-2w3gA:undetectable | 6a60D-2w3gA:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x2g | TRIOSEPHOSPHATEISOMERASE,GLYCOSOMAL (Trypanosomabrucei) |
PF00121(TIM) | 6 | ILE A 147ALA A 149ALA A 151LEU A 154ALA A 110ILE A 208 | None | 1.48A | 6a60D-2x2gA:undetectable | 6a60D-2x2gA:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ynm | LIGHT-INDEPENDENTPROTOCHLOROPHYLLIDEREDUCTASE SUBUNIT N (Prochlorococcusmarinus) |
PF00148(Oxidored_nitro) | 5 | ILE C 247ALA C 251ALA C 250LEU C 232LEU C 166 | None | 1.05A | 6a60D-2ynmC:undetectable | 6a60D-2ynmC:11.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5v | ALPHA-GALACTOSIDASE (Umbelopsisvinacea) |
PF16499(Melibiase_2) | 5 | ILE A 28ALA A 31ALA A 32LEU A 88ILE A 76 | None | 0.91A | 6a60D-3a5vA:undetectable | 6a60D-3a5vA:14.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c1a | PUTATIVEOXIDOREDUCTASE (Magnetospirillummagnetotacticum) |
PF01408(GFO_IDH_MocA) | 6 | ALA A 113ALA A 112ALA A 117ILE A 74HIS A 81LEU A 101 | None | 1.28A | 6a60D-3c1aA:undetectable | 6a60D-3c1aA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cr8 | SULFATEADENYLYLTRANSFERASE,ADENYLYLSULFATEKINASE (Thiobacillusdenitrificans) |
PF01583(APS_kinase)PF01747(ATP-sulfurylase)PF14306(PUA_2) | 5 | ALA A 171LEU A 234ILE A 166CYH A 258LEU A 261 | None | 1.02A | 6a60D-3cr8A:undetectable | 6a60D-3cr8A:9.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3deg | GTP-BINDING PROTEINLEPA (Escherichiacoli) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03144(GTP_EFTU_D2)PF06421(LepA_C) | 5 | ILE C 195ALA C 193GLN C 192ILE C 262LEU C 258 | None | 1.05A | 6a60D-3degC:undetectable | 6a60D-3degC:9.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3dzu | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4) | 12 | ILE A 268ALA A 271ALA A 272GLN A 275LEU A 309PHE A 313ARG A 316ALA A 327ILE A 345CYH A 432HIS A 435LEU A 436 | 9CR A7223 (-3.9A)9CR A7223 (-3.5A)9CR A7223 (-4.2A)9CR A7223 (-4.6A)9CR A7223 ( 4.4A)9CR A7223 (-4.5A)9CR A7223 (-3.7A)9CR A7223 ( 4.7A)9CR A7223 ( 4.9A)9CR A7223 (-3.8A)9CR A7223 (-4.3A)9CR A7223 ( 4.7A) | 0.62A | 6a60D-3dzuA:34.4 | 6a60D-3dzuA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f95 | BETA-GLUCOSIDASE (Pseudoalteromonassp. BB1) |
no annotation | 5 | ILE A 722ALA A 755GLN A 752ILE A 784LEU A 762 | None | 1.02A | 6a60D-3f95A:undetectable | 6a60D-3f95A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fg2 | PUTATIVE RUBREDOXINREDUCTASE (Rhodopseudomonaspalustris) |
PF07992(Pyr_redox_2)PF14759(Reductase_C) | 5 | ILE P 245ALA P 248ALA P 249ILE P 32LEU P 104 | NoneNoneNoneFAD P 449 ( 4.5A)None | 0.99A | 6a60D-3fg2P:undetectable | 6a60D-3fg2P:12.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1l | MITOCHONDRIALUBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEXCORE PROTEIN 2 (Gallus gallus) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | ALA B 339ALA B 340GLN B 343LEU B 295HIS B 254 | None | 1.02A | 6a60D-3h1lB:undetectable | 6a60D-3h1lB:13.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3il3 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Haemophilusinfluenzae) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | ILE A 137ALA A 91GLN A 93ALA A 52ILE A 165 | None | 1.00A | 6a60D-3il3A:undetectable | 6a60D-3il3A:12.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k11 | PUTATIVE GLYCOSYLHYDROLASE (Bacteroidesthetaiotaomicron) |
PF07470(Glyco_hydro_88) | 5 | ILE A 228ALA A 232ALA A 230GLN A 233LEU A 164 | None | 0.99A | 6a60D-3k11A:undetectable | 6a60D-3k11A:10.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k5p | D-3-PHOSPHOGLYCERATEDEHYDROGENASE (Brucellaabortus) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 6 | ALA A 51LEU A 48ALA A 74ILE A 20HIS A 38LEU A 39 | None | 1.40A | 6a60D-3k5pA:undetectable | 6a60D-3k5pA:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l44 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE1 (Bacillusanthracis) |
PF00202(Aminotran_3) | 5 | ILE A 76ALA A 79ALA A 311ILE A 67HIS A 71 | None | 1.01A | 6a60D-3l44A:undetectable | 6a60D-3l44A:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3llk | SULFHYDRYL OXIDASE 1 (Homo sapiens) |
PF04777(Evr1_Alr) | 5 | ALA A 418ALA A 419GLN A 421ALA A 432LEU A 528 | None | 1.05A | 6a60D-3llkA:undetectable | 6a60D-3llkA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lqy | PUTATIVEISOCHORISMATASEHYDROLASE (Oleispiraantarctica) |
PF00857(Isochorismatase) | 5 | ALA A 146ALA A 35GLN A 38ALA A 182ILE A 77 | None | 1.05A | 6a60D-3lqyA:undetectable | 6a60D-3lqyA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mr7 | ADENYLATE/GUANYLATECYCLASE/HYDROLASE,ALPHA/BETA FOLDFAMILY (Ruegeriapomeroyi) |
PF00211(Guanylate_cyc) | 5 | ALA A 66ALA A 67LEU A 8ALA A 45ILE A 102 | None | 1.02A | 6a60D-3mr7A:undetectable | 6a60D-3mr7A:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nze | PUTATIVETRANSCRIPTIONALREGULATOR,SUGAR-BINDING FAMILY (Paenarthrobacteraurescens) |
PF04198(Sugar-bind) | 5 | ILE A 279ALA A 98GLN A 97ILE A 112LEU A 120 | None | 1.02A | 6a60D-3nzeA:undetectable | 6a60D-3nzeA:15.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0m | HIT FAMILY PROTEIN (Mycolicibacteriumsmegmatis) |
PF01230(HIT) | 6 | ILE A 67ALA A 70ALA A 71LEU A 76ALA A 135HIS A 101 | NoneNoneNoneNoneNoneAMP A 155 (-3.8A) | 1.22A | 6a60D-3o0mA:undetectable | 6a60D-3o0mA:24.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pm9 | PUTATIVEOXIDOREDUCTASE (Rhodopseudomonaspalustris) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 5 | ALA A 332GLN A 329PHE A 234ALA A 324ILE A 340 | None | 1.04A | 6a60D-3pm9A:undetectable | 6a60D-3pm9A:11.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qqv | GERANYLGERANYLPYROPHOSPHATESYNTHASE (Corynebacteriumglutamicum) |
PF00348(polyprenyl_synt) | 5 | ALA A 77ALA A 76ALA A 232HIS A 347LEU A 348 | None | 0.82A | 6a60D-3qqvA:undetectable | 6a60D-3qqvA:12.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qr8 | BASEPLATE ASSEMBLYPROTEIN V (Escherichiavirus P2) |
PF04717(Phage_base_V) | 5 | ILE A 69ALA A 71ALA A 79ILE A 23CYH A 33 | None | 1.05A | 6a60D-3qr8A:undetectable | 6a60D-3qr8A:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qyq | DEOXYRIBOSE-PHOSPHATE ALDOLASE, PUTATIVE (Toxoplasmagondii) |
no annotation | 5 | ILE A 157ALA A 160ALA A 161LEU A 172HIS A 189 | None | 1.00A | 6a60D-3qyqA:undetectable | 6a60D-3qyqA:16.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3skd | PUTATIVEUNCHARACTERIZEDPROTEIN TTHB187 (Thermusthermophilus) |
no annotation | 5 | ALA A 164LEU A 71ALA A 9HIS A 153LEU A 154 | None | 1.02A | 6a60D-3skdA:undetectable | 6a60D-3skdA:15.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tm5 | CRYSTAL STRUCTURE OFTRM14 (Pyrococcusfuriosus) |
PF01170(UPF0020)PF02926(THUMP) | 5 | ILE A 206ALA A 207ALA A 209LEU A 74ARG A 191 | None | 1.04A | 6a60D-3tm5A:undetectable | 6a60D-3tm5A:11.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tma | METHYLTRANSFERASE (Thermusthermophilus) |
PF01170(UPF0020)PF02926(THUMP) | 5 | ALA A 173ALA A 175GLN A 174LEU A 53ARG A 158 | None | 1.02A | 6a60D-3tmaA:undetectable | 6a60D-3tmaA:15.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wc3 | ENDO-1,4-BETA-GLUCANASE (Eisenia fetida) |
PF00759(Glyco_hydro_9) | 6 | ALA A 178ALA A 177PHE A 87ALA A 86ILE A 332LEU A 280 | None | 1.05A | 6a60D-3wc3A:undetectable | 6a60D-3wc3A:10.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zdb | PROTEIN XNI (Escherichiacoli) |
PF01367(5_3_exonuc)PF02739(5_3_exonuc_N) | 5 | ALA A 47ALA A 103ILE A 17CYH A 29LEU A 33 | None MG A1255 ( 4.8A)NoneNoneNone | 1.06A | 6a60D-3zdbA:undetectable | 6a60D-3zdbA:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyv | AOX3 (Mus musculus) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 5 | ILE A 333ALA A 336GLN A 340LEU A 368ALA A 427 | None | 0.67A | 6a60D-3zyvA:undetectable | 6a60D-3zyvA:4.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b43 | TRANSLATIONINITIATION FACTORIF-2 (Thermusthermophilus) |
PF00009(GTP_EFTU)PF04760(IF2_N) | 5 | ILE A 149ALA A 147ALA A 173HIS A 84LEU A 86 | None | 1.02A | 6a60D-4b43A:undetectable | 6a60D-4b43A:12.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g0o | PROTEIN ARGONAUTE 5 (Arabidopsisthaliana) |
PF02171(Piwi) | 5 | ILE A 629ALA A 633ALA A 611ILE A 653CYH A 657 | None | 1.03A | 6a60D-4g0oA:undetectable | 6a60D-4g0oA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g7f | ENOLASE (Trypanosomacruzi) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | ILE A 116ALA A 119ALA A 120LEU A 83LEU A 135 | None | 0.90A | 6a60D-4g7fA:undetectable | 6a60D-4g7fA:11.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gfj | TOPOISOMERASE V (Methanopyruskandleri) |
PF13412(HTH_24)PF14520(HHH_5) | 5 | ALA A 366ALA A 367LEU A 356ALA A 401LEU A 343 | None | 1.04A | 6a60D-4gfjA:undetectable | 6a60D-4gfjA:8.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j5x | RETINOIC ACIDRECEPTOR RXR-ALPHA,NUCLEAR RECEPTORCOACTIVATOR 1 (Homo sapiens) |
no annotation | 12 | ILE D 268ALA D 271ALA D 272GLN D 275LEU D 309PHE D 313ARG D 316ALA D 327ILE D 345CYH D 432HIS D 435LEU D 436 | None | 0.48A | 6a60D-4j5xD:33.8 | 6a60D-4j5xD:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nn1 | TRANSCRIPTIONALREGULATOR (Mycobacteriumtuberculosis) |
PF00440(TetR_N) | 5 | ILE A 12ALA A 15ALA A 16GLN A 19ALA A 35 | None | 0.41A | 6a60D-4nn1A:undetectable | 6a60D-4nn1A:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4opf | NRPS/PKS (Streptomycesalbus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | ILE A6123ALA A6124ALA A6352HIS A6282LEU A6281 | None | 1.03A | 6a60D-4opfA:undetectable | 6a60D-4opfA:11.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uqg | DNA POLYMERASE (Geobacillusstearothermophilus) |
PF00476(DNA_pol_A) | 5 | ILE A 804ALA A 801ALA A 800GLN A 797LEU A 862 | None | 1.02A | 6a60D-4uqgA:undetectable | 6a60D-4uqgA:8.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wj1 | ANTIGEN MTB48,MYCOBACTERIALPROTEIN (Mycolicibacteriumsmegmatis) |
no annotation | 5 | ILE A 71ALA A 74ALA A 75LEU A 9HIS A 17 | None | 0.84A | 6a60D-4wj1A:undetectable | 6a60D-4wj1A:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xia | D-XYLOSE ISOMERASE (Arthrobactersp. NRRL B3728) |
PF01261(AP_endonuc_2) | 6 | ILE A 231ALA A 232ALA A 234GLN A 233LEU A 199HIS A 242 | None | 1.49A | 6a60D-4xiaA:undetectable | 6a60D-4xiaA:10.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ynv | ACL4 (Chaetomiumthermophilum) |
PF13432(TPR_16) | 5 | ILE A 46ALA A 49ALA A 50LEU A 74ALA A 37 | None | 0.88A | 6a60D-4ynvA:undetectable | 6a60D-4ynvA:13.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z3l | MAJOR POLLENALLERGEN BET V 1-A (Betula pendula) |
PF00407(Bet_v_1) | 5 | ALA A 146LEU A 29PHE A 30ILE A 102LEU A 18 | None | 0.81A | 6a60D-4z3lA:undetectable | 6a60D-4z3lA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d86 | PROBABLE SIDEROPHOREBIOSYNTHESIS PROTEINSBNA (Staphylococcusaureus) |
PF00291(PALP) | 6 | ILE A 80ALA A 81ALA A 83LEU A 93ALA A 51ILE A 101 | None | 1.48A | 6a60D-5d86A:undetectable | 6a60D-5d86A:11.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5daj | NALD (Pseudomonasaeruginosa) |
PF00440(TetR_N)PF08361(TetR_C_2) | 5 | ILE A 15ALA A 18ALA A 19ALA A 39HIS A 56 | None | 0.97A | 6a60D-5dajA:undetectable | 6a60D-5dajA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gt5 | PECTATE LYASE (Paenibacillussp. 0602) |
no annotation | 5 | ILE A 117ALA A 116ALA A 115PHE A 132LEU A 39 | None | 0.98A | 6a60D-5gt5A:undetectable | 6a60D-5gt5A:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j5v | IMMUNITY PROTEINCDII (Escherichiacoli) |
no annotation | 5 | ILE C 30ALA C 46GLN C 49PHE C 27LEU C 35 | None | 0.95A | 6a60D-5j5vC:undetectable | 6a60D-5j5vC:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j6q | CELL WALL BINDINGPROTEIN CWP8 (Clostridioidesdifficile) |
PF04122(CW_binding_2) | 6 | ILE A 584ALA A 585ALA A 588LEU A 559ILE A 552LEU A 577 | NoneSO4 A 705 (-3.8A)NoneNoneNoneNone | 1.49A | 6a60D-5j6qA:undetectable | 6a60D-5j6qA:7.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbw | 3-HYDROXYBUTYRYL-COADEHYDRATASE (Myxococcusxanthus) |
PF00378(ECH_1) | 5 | ILE A 102ALA A 101ALA A 100ALA A 190ILE A 166 | None | 1.02A | 6a60D-5jbwA:undetectable | 6a60D-5jbwA:17.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jr9 | NEQ131 (Nanoarchaeumequitans) |
PF01997(Translin) | 5 | ALA B 59GLN B 62LEU B 80ILE B 37LEU B 87 | None | 1.01A | 6a60D-5jr9B:undetectable | 6a60D-5jr9B:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mza | ERYTHROCYTE MEMBRANEPROTEIN 1 (PFEMP1) (Plasmodiumfalciparum) |
PF05424(Duffy_binding) | 5 | ALA A 878ALA A 877LEU A 876ALA A 974ILE A 935 | None | 0.92A | 6a60D-5mzaA:undetectable | 6a60D-5mzaA:9.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uan | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
no annotation | 7 | ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316ALA A 327ILE A 428 | 9CR A 503 (-3.5A)9CR A 503 (-3.5A)9CR A 503 (-3.8A)9CR A 503 (-4.7A)9CR A 503 (-3.0A)9CR A 503 (-3.4A)None | 1.46A | 6a60D-5uanA:34.5 | 6a60D-5uanA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uan | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
no annotation | 11 | ILE A 268ALA A 271ALA A 272GLN A 275LEU A 309PHE A 313ALA A 327ILE A 345CYH A 432HIS A 435LEU A 436 | 9CR A 503 (-4.0A)9CR A 503 (-3.5A)9CR A 503 (-3.5A)9CR A 503 (-3.8A)9CR A 503 (-3.7A)9CR A 503 (-4.7A)9CR A 503 (-3.4A)None9CR A 503 (-3.3A)None9CR A 503 ( 4.8A) | 0.59A | 6a60D-5uanA:34.5 | 6a60D-5uanA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uan | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
no annotation | 11 | ILE A 268ALA A 271ALA A 272GLN A 275LEU A 309PHE A 313ARG A 316ALA A 327ILE A 345CYH A 432LEU A 436 | 9CR A 503 (-4.0A)9CR A 503 (-3.5A)9CR A 503 (-3.5A)9CR A 503 (-3.8A)9CR A 503 (-3.7A)9CR A 503 (-4.7A)9CR A 503 (-3.0A)9CR A 503 (-3.4A)None9CR A 503 (-3.3A)9CR A 503 ( 4.8A) | 0.69A | 6a60D-5uanA:34.5 | 6a60D-5uanA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uvm | HISTIDINE TRIAD(HIT) PROTEIN (Ruminiclostridiumthermocellum) |
PF11969(DcpS_C) | 5 | ILE A 64ALA A 67ALA A 68LEU A 103ALA A 27 | None | 0.88A | 6a60D-5uvmA:undetectable | 6a60D-5uvmA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v4a | GLYCOSYLTRANSFERASE(DUF1792) (Streptococcussanguinis) |
PF08759(GT-D) | 5 | ILE A 183ALA A 186LEU A 144ALA A 269LEU A 211 | None | 1.04A | 6a60D-5v4aA:undetectable | 6a60D-5v4aA:16.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnz | CRED (Streptomycescremeus) |
no annotation | 5 | ILE A 54ALA A 57ALA A 58LEU A 30ALA A 89 | None | 0.92A | 6a60D-5xnzA:undetectable | 6a60D-5xnzA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xym | 50S RIBOSOMALPROTEIN L22 (Mycolicibacteriumsmegmatis) |
PF00237(Ribosomal_L22) | 5 | ALA S 61ALA S 62LEU S 76ALA S 10LEU S 40 | None | 0.96A | 6a60D-5xymS:undetectable | 6a60D-5xymS:25.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xym | 50S RIBOSOMALPROTEIN L22 (Mycolicibacteriumsmegmatis) |
PF00237(Ribosomal_L22) | 6 | ILE S 58ALA S 61ALA S 62LEU S 76ALA S 10ILE S 42 | None | 1.16A | 6a60D-5xymS:undetectable | 6a60D-5xymS:25.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zmy | - (-) |
no annotation | 5 | ALA A 256ALA A 255LEU A 251PHE A 252LEU A 28 | None | 1.01A | 6a60D-5zmyA:undetectable | 6a60D-5zmyA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bma | INDOLE-3-GLYCEROLPHOSPHATE SYNTHASE (Campylobacterjejuni) |
no annotation | 5 | ILE A 184ALA A 182LEU A 140ALA A 177ILE A 54 | None | 1.05A | 6a60D-6bmaA:undetectable | 6a60D-6bmaA:15.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c4r | STAPHYLOPINEDEHYDROGENASE (Staphylococcusaureus) |
no annotation | 5 | ILE A 185ALA A 189GLN A 191ILE A 117LEU A 170 | None | 1.05A | 6a60D-6c4rA:undetectable | 6a60D-6c4rA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d95 | - (-) |
no annotation | 5 | ILE A 129ALA A 132ALA A 133ALA A 266ILE A 180 | None | 0.94A | 6a60D-6d95A:undetectable | 6a60D-6d95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d95 | - (-) |
no annotation | 5 | ILE A 129ALA A 132ALA A 133LEU A 138ALA A 266 | None | 0.90A | 6a60D-6d95A:undetectable | 6a60D-6d95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eih | 14-3-3 PROTEINEPSILON (Homo sapiens) |
no annotation | 5 | ALA A 145ALA A 144ILE A 53CYH A 97LEU A 101 | None | 1.05A | 6a60D-6eihA:undetectable | 6a60D-6eihA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ez8 | HUNTINGTIN (Homo sapiens) |
no annotation | 5 | ILE A1791ALA A1794ALA A1795LEU A1741HIS A1781 | None | 1.04A | 6a60D-6ez8A:undetectable | 6a60D-6ez8A:15.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ez8 | HUNTINGTIN (Homo sapiens) |
no annotation | 5 | ILE A1791ALA A1794PHE A1736ILE A1680HIS A1781 | None | 0.99A | 6a60D-6ez8A:undetectable | 6a60D-6ez8A:15.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gdg | TRXA,ADENOSINERECEPTOR A2A (Escherichiacoli;Homo sapiens) |
no annotation | 5 | ILE A 200ALA A 203ALA A 204GLN A 207ILE A 238 | None | 0.98A | 6a60D-6gdgA:undetectable | 6a60D-6gdgA:17.11 |