SIMILAR PATTERNS OF AMINO ACIDS FOR 5ZVG_A_SAMA401_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxn PROTEIN (RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN)

(Cupriavidus
necator) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		3 ASP A 201
ARG A 423
ASP A 166
 None
 0.77A 5zvgA-1bxnA:
undetectable		 5zvgA-1bxnA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3h GUANOSINE
PENTAPHOSPHATE
SYNTHETASE

(Streptomyces
antibioticus) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03726
(PNPase) 		3 ASP A  42
ARG A  20
ASP A 130
 None
 0.89A 5zvgA-1e3hA:
undetectable		 5zvgA-1e3hA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gs9 APOLIPOPROTEIN E

(Homo sapiens) 		PF01442
(Apolipoprotein) 		3 ASP A 151
ARG A 103
ASP A 110
 None
 0.75A 5zvgA-1gs9A:
undetectable		 5zvgA-1gs9A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h54 MALTOSE
PHOSPHORYLASE

(Lactobacillus
brevis) 		PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N) 		3 ASP A  41
ARG A  39
ASP A  49
 None
 0.75A 5zvgA-1h54A:
undetectable		 5zvgA-1h54A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h81 POLYAMINE OXIDASE

(Zea mays) 		PF01593
(Amino_oxidase) 		3 ASP A 416
ARG A 412
ASP A 449
 None
 0.80A 5zvgA-1h81A:
2.1		 5zvgA-1h81A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hg0 L-ASPARAGINASE

(Dickeya
chrysanthemi) 		PF00710
(Asparaginase) 		3 ASP A 130
ARG A 122
ASP A 175
 None
 0.80A 5zvgA-1hg0A:
undetectable		 5zvgA-1hg0A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i5p PESTICIDIAL CRYSTAL
PROTEIN CRY2AA

(Bacillus
thuringiensis) 		PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N)
PF09131
(Endotoxin_mid) 		3 ASP A 618
ARG A 524
ASP A 521
 None
 0.84A 5zvgA-1i5pA:
undetectable		 5zvgA-1i5pA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT

(Galdieria
partita) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		3 ASP A 198
ARG A 421
ASP A 163
 None
 0.86A 5zvgA-1iwaA:
undetectable		 5zvgA-1iwaA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l2u OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Escherichia
coli) 		PF00215
(OMPdecase) 		3 ASP A  34
ARG A  64
ASP A  27
 None
 0.82A 5zvgA-1l2uA:
undetectable		 5zvgA-1l2uA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1miv TRNA CCA-ADDING
ENZYME

(Geobacillus
stearothermophilus) 		PF01743
(PolyA_pol)
PF12627
(PolyA_pol_RNAbd)
PF13735
(tRNA_NucTran2_2) 		3 ASP A 107
ARG A 110
ASP A  42
 None
 0.86A 5zvgA-1mivA:
undetectable		 5zvgA-1mivA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qho ALPHA-AMYLASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		3 ASP A 518
ARG A 545
ASP A   9
 None
 0.80A 5zvgA-1qhoA:
undetectable		 5zvgA-1qhoA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qxo CHORISMATE SYNTHASE

(Streptococcus
pneumoniae) 		PF01264
(Chorismate_synt) 		3 ASP A 123
ARG A 125
ASP A 112
 None
 0.81A 5zvgA-1qxoA:
undetectable		 5zvgA-1qxoA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1slq VP4

(Rotavirus A) 		PF17477
(Rota_VP4_MID)
PF17478
(VP4_helical) 		3 ASP A 478
ARG A 363
ASP A 253
 None
 0.84A 5zvgA-1slqA:
undetectable		 5zvgA-1slqA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT

(Blastochloris
viridis) 		PF02276
(CytoC_RC) 		3 ASP C 304
ARG C 146
ASP C 238
 None
 0.74A 5zvgA-1vrnC:
undetectable		 5zvgA-1vrnC:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yq2 BETA-GALACTOSIDASE

(Arthrobacter
sp. C2-2) 		PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		3 ASP A 929
ARG A 955
ASP A 714
 None
 0.88A 5zvgA-1yq2A:
undetectable		 5zvgA-1yq2A:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2an2 P332G A333S DOUBLE
MUTANT OF NITRIC
OXIDE SYNTHASE FROM
BACILLUS SUBTILIS

(Bacillus
subtilis) 		PF02898
(NO_synthase) 		3 ASP A 141
ARG A 128
ASP A 247
 None
ARG  A2000 (-4.0A)
None
 0.87A 5zvgA-2an2A:
undetectable		 5zvgA-2an2A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2axq SACCHAROPINE
DEHYDROGENASE

(Saccharomyces
cerevisiae) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		3 ASP A 337
ARG A 176
ASP A 266
 None
 0.70A 5zvgA-2axqA:
4.5		 5zvgA-2axqA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b9e NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 ASP A 258
ARG A 263
ASP A 305
 SAM  A1201 (-2.6A)
SAM  A1201 (-3.9A)
SAM  A1201 (-3.7A)
 0.78A 5zvgA-2b9eA:
30.6		 5zvgA-2b9eA:
26.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bq8 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5

(Homo sapiens) 		PF00149
(Metallophos) 		3 ASP X  62
ARG X  64
ASP X  91
 None
 0.88A 5zvgA-2bq8X:
undetectable		 5zvgA-2bq8X:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cy8 D-PHENYLGLYCINE
AMINOTRANSFERASE

(Pseudomonas
stutzeri) 		PF00202
(Aminotran_3) 		3 ASP A  27
ARG A  22
ASP A  37
 None
 0.85A 5zvgA-2cy8A:
undetectable		 5zvgA-2cy8A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d6f GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT D
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT E

(Methanothermobacter
thermautotrophicus;
Methanothermobacter
thermautotrophicus) 		PF00710
(Asparaginase)
PF02637
(GatB_Yqey)
PF02934
(GatB_N)
PF02938
(GAD) 		3 ASP A 241
ARG C  43
ASP A 261
 None
 0.87A 5zvgA-2d6fA:
undetectable		 5zvgA-2d6fA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eid GALACTOSE OXIDASE

(Fusarium
graminearum) 		PF00754
(F5_F8_type_C)
PF01344
(Kelch_1)
PF09118
(DUF1929) 		3 ASP A 324
ARG A 330
ASP A 407
 None
 0.87A 5zvgA-2eidA:
undetectable		 5zvgA-2eidA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6d GLUCOAMYLASE GLU1

(Saccharomycopsis
fibuligera) 		PF00723
(Glyco_hydro_15) 		3 ASP A 160
ARG A 156
ASP A  84
 None
 0.74A 5zvgA-2f6dA:
undetectable		 5zvgA-2f6dA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fw2 TESTIS-SPECIFIC
CHROMODOMAIN PROTEIN
Y 2

(Homo sapiens) 		PF00378
(ECH_1) 		3 ASP A   5
ARG A   4
ASP A  66
 None
 0.84A 5zvgA-2fw2A:
undetectable		 5zvgA-2fw2A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jk0 L-ASPARAGINASE

(Pectobacterium
carotovorum) 		PF00710
(Asparaginase) 		3 ASP A 130
ARG A 122
ASP A 175
 None
 0.80A 5zvgA-2jk0A:
undetectable		 5zvgA-2jk0A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k4z DSRR

(Allochromatium
vinosum) 		PF01521
(Fe-S_biosyn) 		3 ASP A  51
ARG A  27
ASP A  66
 None
 0.79A 5zvgA-2k4zA:
undetectable		 5zvgA-2k4zA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k7b CALCIUM-BINDING
PROTEIN 1

(Homo sapiens) 		PF13499
(EF-hand_7) 		3 ASP A  46
ARG A  45
ASP A  39
 None
None
MG  A 601 (-3.5A)
 0.85A 5zvgA-2k7bA:
undetectable		 5zvgA-2k7bA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kbq HARMONIN

(Homo sapiens) 		no annotation 3 ASP A  14
ARG A  10
ASP A  20
 None
 0.80A 5zvgA-2kbqA:
undetectable		 5zvgA-2kbqA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m5t HUMAN RHINOVIRUS 2A
PROTEINASE

(Rhinovirus C) 		PF00947
(Pico_P2A) 		3 ASP A 131
ARG A 133
ASP A  75
 None
 0.74A 5zvgA-2m5tA:
undetectable		 5zvgA-2m5tA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o61 TRANSCRIPTION FACTOR
P65/INTERFERON
REGULATORY FACTOR
7/INTERFERON
REGULATORY FACTOR 3
FUSION PROTEIN

(Homo sapiens) 		PF00554
(RHD_DNA_bind)
PF00605
(IRF)
PF16179
(RHD_dimer) 		3 ASP A2069
ARG A2068
ASP A1114
 None
 0.77A 5zvgA-2o61A:
undetectable		 5zvgA-2o61A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oz8 MLL7089 PROTEIN

(Mesorhizobium
japonicum) 		PF13378
(MR_MLE_C) 		3 ASP A  16
ARG A  17
ASP A 322
 None
 0.85A 5zvgA-2oz8A:
undetectable		 5zvgA-2oz8A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rcq RETINOL-BINDING
PROTEIN II, CELLULAR

(Homo sapiens) 		PF00061
(Lipocalin) 		3 ASP A   3
ARG A 137
ASP A  43
 None
 0.66A 5zvgA-2rcqA:
undetectable		 5zvgA-2rcqA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rcq RETINOL-BINDING
PROTEIN II, CELLULAR

(Homo sapiens) 		PF00061
(Lipocalin) 		3 ASP A   3
ARG A 137
ASP A  45
 None
 0.67A 5zvgA-2rcqA:
undetectable		 5zvgA-2rcqA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vak SIGMA A

(Avian
orthoreovirus) 		PF03084
(Sigma_1_2) 		3 ASP A 257
ARG A 252
ASP A 286
 None
 0.61A 5zvgA-2vakA:
undetectable		 5zvgA-2vakA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdc GLUTAMATE SYNTHASE
[NADPH] LARGE CHAIN

(Azospirillum
brasilense) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		3 ASP A 408
ARG A 404
ASP A 311
 None
 0.77A 5zvgA-2vdcA:
undetectable		 5zvgA-2vdcA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vp3 VP39

(Vaccinia virus) 		PF01358
(PARP_regulatory) 		3 ASP A  95
ARG A  97
ASP A 138
 SAH  A 400 (-2.6A)
SAH  A 400 (-3.9A)
SAH  A 400 (-3.7A)
 0.79A 5zvgA-2vp3A:
8.4		 5zvgA-2vp3A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zuf ARGINYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		3 ASP A  40
ARG A 547
ASP A  35
 None
 0.85A 5zvgA-2zufA:
undetectable		 5zvgA-2zufA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3akc CYTIDYLATE KINASE

(Thermus
thermophilus) 		PF02224
(Cytidylate_kin) 		3 ASP A 175
ARG A 126
ASP A  94
 CDP  A 209 (-2.8A)
CDP  A 209 (-3.0A)
None
 0.83A 5zvgA-3akcA:
undetectable		 5zvgA-3akcA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c5w PP2A-SPECIFIC
METHYLESTERASE PME-1

(Homo sapiens) 		PF12697
(Abhydrolase_6) 		3 ASP P 354
ARG P 222
ASP P 181
 None
 0.83A 5zvgA-3c5wP:
2.1		 5zvgA-3c5wP:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3frm UNCHARACTERIZED
CONSERVED PROTEIN

(Staphylococcus
epidermidis) 		PF13673
(Acetyltransf_10) 		3 ASP A 177
ARG A 163
ASP A  12
 None
 0.74A 5zvgA-3frmA:
undetectable		 5zvgA-3frmA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE

(Plasmodium
falciparum) 		PF00956
(NAP) 		3 ASP A  80
ARG A 132
ASP A  73
 None
 0.88A 5zvgA-3fs3A:
undetectable		 5zvgA-3fs3A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7u ALDO-KETO REDUCTASE

(Arabidopsis
thaliana) 		PF00248
(Aldo_ket_red) 		3 ASP A 109
ARG A 153
ASP A  75
 None
 0.74A 5zvgA-3h7uA:
undetectable		 5zvgA-3h7uA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k0z PUTATIVE POLYKETIDE
CYCLASE

(Bacillus cereus) 		PF07366
(SnoaL) 		3 ASP A  84
ARG A  91
ASP A 147
 None
NHE  A   1 (-3.9A)
None
 0.81A 5zvgA-3k0zA:
undetectable		 5zvgA-3k0zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kh8 MAOC-LIKE
DEHYDRATASE

(Phytophthora
capsici) 		PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N) 		3 ASP A  24
ARG A  23
ASP A  65
 None
 0.85A 5zvgA-3kh8A:
undetectable		 5zvgA-3kh8A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l10 PROLIFERATING CELL
NUCLEAR ANTIGEN

(Saccharomyces
cerevisiae) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		3 ASP A  63
ARG A  61
ASP A  93
 None
 0.79A 5zvgA-3l10A:
undetectable		 5zvgA-3l10A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lah METHYL-ACCEPTING
CHEMOTAXIS PROTEIN

(Caldanaerobacter
subterraneus) 		PF07700
(HNOB) 		3 ASP A  45
ARG A 135
ASP A  42
 None
HEM  A 200 (-3.6A)
None
 0.84A 5zvgA-3lahA:
undetectable		 5zvgA-3lahA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mi6 ALPHA-GALACTOSIDASE

(Lactobacillus
brevis) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		3 ASP A 375
ARG A 389
ASP A 421
 None
 0.84A 5zvgA-3mi6A:
undetectable		 5zvgA-3mi6A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3moi PROBABLE
DEHYDROGENASE

(Bordetella
bronchiseptica) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 ASP A 155
ARG A 159
ASP A 239
 None
 0.88A 5zvgA-3moiA:
4.3		 5zvgA-3moiA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qyf CRISPR-ASSOCIATED
PROTEIN

(Sulfolobus
solfataricus) 		PF09651
(Cas_APE2256) 		3 ASP A  74
ARG A  67
ASP A 195
 None
None
MG  A 322 (-2.2A)
 0.80A 5zvgA-3qyfA:
3.0		 5zvgA-3qyfA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfz APOPTOTIC PEPTIDASE
ACTIVATING FACTOR 1

(Mus musculus) 		PF00400
(WD40)
PF00931
(NB-ARC)
PF12894
(ANAPC4_WD40) 		3 ASP A 626
ARG A 629
ASP A 668
 None
 0.80A 5zvgA-3sfzA:
undetectable		 5zvgA-3sfzA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tos CALS11

(Micromonospora
echinospora) 		PF05711
(TylF) 		3 ASP A 151
ARG A  91
ASP A 145
 None
 0.75A 5zvgA-3tosA:
1.5		 5zvgA-3tosA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqw METHIONINE-BINDING
PROTEIN

(Coxiella
burnetii) 		PF03180
(Lipoprotein_9) 		3 ASP A  51
ARG A   3
ASP A  47
 None
 0.83A 5zvgA-3tqwA:
undetectable		 5zvgA-3tqwA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ucq AMYLOSUCRASE

(Deinococcus
geothermalis) 		PF00128
(Alpha-amylase) 		3 ASP A 175
ARG A 282
ASP A 137
 None
GOL  A 721 (-3.4A)
GOL  A 720 (-2.6A)
 0.85A 5zvgA-3ucqA:
undetectable		 5zvgA-3ucqA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uw2 PHOSPHOGLUCOMUTASE/P
HOSPHOMANNOMUTASE
FAMILY PROTEIN

(Burkholderia
thailandensis) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ASP A 247
ARG A 248
ASP A  11
 ZN  A 474 ( 2.5A)
GOL  A 472 ( 4.0A)
None
 0.80A 5zvgA-3uw2A:
undetectable		 5zvgA-3uw2A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wec CYTOCHROME P450

(Rhodococcus
erythropolis) 		PF00067
(p450) 		3 ASP A 241
ARG A 212
ASP A  94
 None
 0.79A 5zvgA-3wecA:
undetectable		 5zvgA-3wecA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wmx NAD DEPENDENT
EPIMERASE/DEHYDRATAS
E

(Cupriavidus
necator) 		PF01370
(Epimerase) 		3 ASP A 165
ARG A 113
ASP A 233
 None
 0.83A 5zvgA-3wmxA:
5.6		 5zvgA-3wmxA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a1o BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH

(Mycobacterium
tuberculosis) 		PF01808
(AICARFT_IMPCHas)
PF02142
(MGS) 		3 ASP A 273
ARG A 269
ASP A 389
 None
 0.82A 5zvgA-4a1oA:
2.8		 5zvgA-4a1oA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e0t CYCLIC DIPEPTIDE
N-PRENYLTRANSFERASE

(Aspergillus
fumigatus) 		PF11991
(Trp_DMAT) 		3 ASP A 291
ARG A 298
ASP A 269
 None
 0.85A 5zvgA-4e0tA:
undetectable		 5zvgA-4e0tA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzv PUTATIVE
METHYLTRANSFERASE
NSUN4

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 ASP A 204
ARG A 209
ASP A 255
 SAM  A 401 (-2.9A)
SAM  A 401 (-3.6A)
SAM  A 401 (-3.7A)
 0.34A 5zvgA-4fzvA:
28.5		 5zvgA-4fzvA:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3n DNA GYRASE SUBUNIT A

(Mycobacterium
tuberculosis) 		PF03989
(DNA_gyraseA_C) 		3 ASP A 565
ARG A 615
ASP A 515
 None
 0.83A 5zvgA-4g3nA:
undetectable		 5zvgA-4g3nA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gkl ALPHA-AMYLASE

(Thermotoga
neapolitana) 		PF00128
(Alpha-amylase) 		3 ASP A 138
ARG A 128
ASP A 169
 None
 0.77A 5zvgA-4gklA:
undetectable		 5zvgA-4gklA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i0k CD276 ANTIGEN

(Mus musculus) 		PF07686
(V-set)
PF13927
(Ig_3) 		3 ASP A 116
ARG A 113
ASP A  45
 None
SO4  A 306 (-2.4A)
None
 0.62A 5zvgA-4i0kA:
undetectable		 5zvgA-4i0kA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhz BETA-GLUCURONIDASE

(Escherichia
coli) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		3 ASP A  89
ARG A  87
ASP A 339
 None
 0.87A 5zvgA-4jhzA:
undetectable		 5zvgA-4jhzA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3z D-ERYTHRULOSE
4-PHOSPHATE
DEHYDROGENASE

(Brucella
melitensis) 		no annotation 3 ASP A  34
ARG A  68
ASP A 302
 None
 0.87A 5zvgA-4k3zA:
undetectable		 5zvgA-4k3zA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mwg PUTATIVE
DIHYDROMETHANOPTERIN
REDUCTASE (AFPA)

(Paraburkholderia
xenovorans) 		PF02441
(Flavoprotein) 		3 ASP A  43
ARG A  69
ASP A  15
 None
 0.85A 5zvgA-4mwgA:
undetectable		 5zvgA-4mwgA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pyr PUTATIVE
BRANCHED-CHAIN AMINO
ACID ABC TRANSPORTER

(Chromobacterium
violaceum) 		PF04348
(LppC) 		3 ASP A 115
ARG A 317
ASP A 338
 None
 0.82A 5zvgA-4pyrA:
3.0		 5zvgA-4pyrA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pyr PUTATIVE
BRANCHED-CHAIN AMINO
ACID ABC TRANSPORTER

(Chromobacterium
violaceum) 		PF04348
(LppC) 		3 ASP A 338
ARG A 341
ASP A 363
 None
 0.86A 5zvgA-4pyrA:
3.0		 5zvgA-4pyrA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgk UNCHARACTERIZED
PROTEIN

(Yersinia pestis) 		PF07350
(DUF1479) 		3 ASP A 183
ARG A 184
ASP A 202
 EDO  A 505 ( 4.3A)
None
SO4  A 506 (-2.8A)
 0.79A 5zvgA-4rgkA:
undetectable		 5zvgA-4rgkA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rs2 PREDICTED
ACYLTRANSFERASE WITH
ACYL-COA
N-ACYLTRANSFERASE
DOMAIN

(Escherichia
coli) 		PF13508
(Acetyltransf_7) 		3 ASP A  15
ARG A  19
ASP A  33
 None
 0.87A 5zvgA-4rs2A:
undetectable		 5zvgA-4rs2A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd1 ACETOACETATE-COA
LIGASE

(Streptomyces
lividans) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N) 		3 ASP A 406
ARG A 402
ASP A 414
 EDO  A 708 (-4.7A)
None
None
 0.75A 5zvgA-4wd1A:
undetectable		 5zvgA-4wd1A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xl5 BGFP-A

(synthetic
construct) 		PF02985
(HEAT)
PF13646
(HEAT_2) 		3 ASP C  74
ARG C  76
ASP C  43
 None
 0.82A 5zvgA-4xl5C:
undetectable		 5zvgA-4xl5C:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ydh FORMIN-LIKE PROTEIN
1

(Homo sapiens) 		PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 ASP A 294
ARG A 305
ASP A 287
 None
 0.88A 5zvgA-4ydhA:
undetectable		 5zvgA-4ydhA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z2e DNA GYRASE SUBUNIT A

(Streptococcus
pneumoniae) 		PF00521
(DNA_topoisoIV) 		3 ASP A 366
ARG A 362
ASP A 450
 None
 0.87A 5zvgA-4z2eA:
undetectable		 5zvgA-4z2eA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zc0 REPLICATIVE DNA
HELICASE

(Helicobacter
pylori) 		PF00772
(DnaB)
PF03796
(DnaB_C) 		3 ASP A 381
ARG A 336
ASP A 374
 None
 0.59A 5zvgA-4zc0A:
undetectable		 5zvgA-4zc0A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE

(Sulfolobus
acidocaldarius) 		no annotation 3 ASP A 159
ARG A 187
ASP A  93
 None
 0.80A 5zvgA-5a7tA:
undetectable		 5zvgA-5a7tA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ady GTPASE HFLX

(Escherichia
coli) 		PF01926
(MMR_HSR1)
PF13167
(GTP-bdg_N)
PF16360
(GTP-bdg_M) 		3 ASP 6  81
ARG 6 103
ASP 6  26
 None
 0.62A 5zvgA-5ady6:
undetectable		 5zvgA-5ady6:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b0l MOEN5,DNA-BINDING
PROTEIN 7D

(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		no annotation 3 ASP A 197
ARG A 205
ASP A 191
 None
 0.85A 5zvgA-5b0lA:
undetectable		 5zvgA-5b0lA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dfa BETA-GALACTOSIDASE

(Geobacillus
stearothermophilus) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		3 ASP A 606
ARG A 549
ASP A 601
 None
 0.85A 5zvgA-5dfaA:
undetectable		 5zvgA-5dfaA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dwu CYTOKINE RECEPTOR
COMMON SUBUNIT BETA
CYTOKINE RECEPTOR
COMMON SUBUNIT BETA

(Homo sapiens;
Homo sapiens) 		no annotation
PF00041
(fn3)
PF09240
(IL6Ra-bind) 		3 ASP A 116
ARG A 117
ASP B 241
 NAG  A 301 ( 4.9A)
None
None
 0.77A 5zvgA-5dwuA:
undetectable		 5zvgA-5dwuA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fic SPHINGOMYELIN
PHOSPHODIESTERASE

(Mus musculus) 		PF00149
(Metallophos) 		3 ASP A 208
ARG A 226
ASP A 289
 None
 0.87A 5zvgA-5ficA:
undetectable		 5zvgA-5ficA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078

(Thermobifida
fusca) 		PF04261
(Dyp_perox) 		3 ASP A 356
ARG A 352
ASP A 134
 None
 0.85A 5zvgA-5fw4A:
undetectable		 5zvgA-5fw4A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjv VOLTAGE-DEPENDENT
L-TYPE CALCIUM
CHANNEL SUBUNIT
ALPHA-1S

(Oryctolagus
cuniculus) 		PF00520
(Ion_trans)
PF08763
(Ca_chan_IQ)
PF16905
(GPHH) 		3 ASP A1196
ARG A1236
ASP A1203
 None
 0.85A 5zvgA-5gjvA:
undetectable		 5zvgA-5gjvA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gt5 PECTATE LYASE

(Paenibacillus
sp. 0602) 		no annotation 3 ASP A 178
ARG A 276
ASP A 150
 None
 0.74A 5zvgA-5gt5A:
undetectable		 5zvgA-5gt5A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j46 PEPTIDE DEFORMYLASE

(Burkholderia
multivorans) 		PF01327
(Pep_deformylase) 		3 ASP A  39
ARG A  41
ASP A  36
 None
 0.67A 5zvgA-5j46A:
undetectable		 5zvgA-5j46A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jh1 ALDOSE REDUCTASE,
AKR4C7

(Zea mays) 		PF00248
(Aldo_ket_red) 		3 ASP A 106
ARG A 149
ASP A  72
 None
 0.79A 5zvgA-5jh1A:
undetectable		 5zvgA-5jh1A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jp9 CMP
5-HYDROXYMETHYLASE

(Streptomyces
rimofaciens) 		PF00303
(Thymidylat_synt) 		3 ASP A 305
ARG A 306
ASP A 274
 None
 0.84A 5zvgA-5jp9A:
undetectable		 5zvgA-5jp9A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mfa MYELOPEROXIDASE

(Homo sapiens) 		PF03098
(An_peroxidase) 		3 ASP A 566
ARG A 236
ASP A 240
 None
 0.88A 5zvgA-5mfaA:
undetectable		 5zvgA-5mfaA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg8 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
6

(Schizosaccharomyces
pombe) 		no annotation 3 ASP B 654
ARG B 656
ASP B 676
 None
 0.87A 5zvgA-5mg8B:
undetectable		 5zvgA-5mg8B:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzv NANOBODY 22E11

(Lama glama) 		no annotation 3 ASP D  66
ARG D  67
ASP D  62
 None
 0.63A 5zvgA-5mzvD:
undetectable		 5zvgA-5mzvD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6v AMYLOSUCRASE

(Neisseria
polysaccharea) 		no annotation 3 ASP A 182
ARG A 284
ASP A 144
 None
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
 0.80A 5zvgA-5n6vA:
undetectable		 5zvgA-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ocp -

(-) 		no annotation 3 ASP A  88
ARG A  89
ASP A 223
 AHR  A 407 ( 2.6A)
FUB  A 408 ( 3.9A)
AHR  A 407 ( 2.8A)
 0.85A 5zvgA-5ocpA:
undetectable		 5zvgA-5ocpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tg8 HEMAGGLUTININ HA1
CHAIN

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		3 ASP A 298
ARG A 300
ASP A 271
 None
 0.65A 5zvgA-5tg8A:
undetectable		 5zvgA-5tg8A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wm4 SALICYLATE-AMP
LIGASE

(Streptomyces
gandocaensis) 		no annotation 3 ASP A 226
ARG A  37
ASP A 204
 None
 0.78A 5zvgA-5wm4A:
undetectable		 5zvgA-5wm4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z5k NETRIN RECEPTOR DCC
DRAXIN

(Rattus
norvegicus;
Rattus
norvegicus) 		no annotation
no annotation 		3 ASP B 300
ARG B 308
ASP A  77
 None
 0.86A 5zvgA-5z5kB:
undetectable		 5zvgA-5z5kB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b0e 1260 ANTIBODY, HEAVY
CHAIN

(Homo sapiens) 		no annotation 3 ASP B  95
ARG B  96
ASP B  58
 None
 0.57A 5zvgA-6b0eB:
undetectable		 5zvgA-6b0eB:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byo VOLTAGE-DEPENDENT
L-TYPE CALCIUM
CHANNEL SUBUNIT
ALPHA-1S

(Oryctolagus
cuniculus) 		no annotation 3 ASP A1196
ARG A1236
ASP A1203
 None
 0.87A 5zvgA-6byoA:
undetectable		 5zvgA-6byoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d3u ULVAN LYASE

(Nonlabens
ulvanivorans) 		no annotation 3 ASP A 109
ARG A  64
ASP A 173
 None
None
PO4  A 403 ( 4.1A)
 0.86A 5zvgA-6d3uA:
undetectable		 5zvgA-6d3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dg4 ULP1-LIKE SUMO
PROTEASE

(Chaetomium
thermophilum) 		no annotation 3 ASP A  48
ARG A  47
ASP A  62
 None
GOL  A 303 (-2.6A)
None
 0.61A 5zvgA-6dg4A:
undetectable		 5zvgA-6dg4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1

(Saccharomyces
cerevisiae) 		no annotation 3 ASP A 856
ARG A 900
ASP A 793
 None
 0.65A 5zvgA-6eojA:
undetectable		 5zvgA-6eojA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6etz BETA-GALACTOSIDASE

(Arthrobacter
sp. 32cB) 		no annotation 3 ASP A 830
ARG A 815
ASP A 849
 None
MLI  A1106 (-3.6A)
None
 0.88A 5zvgA-6etzA:
undetectable		 5zvgA-6etzA:
undetectable