SIMILAR PATTERNS OF AMINO ACIDS FOR 5ZJI_B_PQNB842_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a59 CITRATE SYNTHASE

(Antarctic
bacterium
DS2-3R) 		PF00285
(Citrate_synt) 		5 TRP A 349
ILE A 213
ILE A  19
ALA A 351
ALA A 123
 None
 1.30A 5zjiB-1a59A:
0.0		 5zjiB-1a59A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ayo ALPHA-2-MACROGLOBULI
N

(Bos taurus) 		PF07677
(A2M_recep) 		5 ILE A  81
ILE A  35
ALA A   7
LEU A   8
ALA A 125
 None
 1.30A 5zjiB-1ayoA:
undetectable		 5zjiB-1ayoA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cbf COBALT-PRECORRIN-4
TRANSMETHYLASE

(Bacillus
megaterium) 		PF00590
(TP_methylase) 		5 ILE A 220
ILE A 146
ALA A 248
LEU A 249
ALA A 245
 None
 1.30A 5zjiB-1cbfA:
0.0		 5zjiB-1cbfA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d4e FLAVOCYTOCHROME C
FUMARATE REDUCTASE

(Shewanella
oneidensis) 		PF00890
(FAD_binding_2)
PF14537
(Cytochrom_c3_2) 		5 ILE A 131
ILE A  65
ALA A 257
LEU A 138
ALA A 139
 FAD  A 600 ( 4.7A)
None
None
None
None
 1.31A 5zjiB-1d4eA:
0.0		 5zjiB-1d4eA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dkg MOLECULAR CHAPERONE
DNAK
NUCLEOTIDE EXCHANGE
FACTOR GRPE

(Escherichia
coli) 		PF00012
(HSP70)
PF01025
(GrpE) 		5 MET A 189
ILE D 286
ALA D 258
LEU D 257
ALA A 158
 None
 1.45A 5zjiB-1dkgA:
undetectable		 5zjiB-1dkgA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ecg GLUTAMINE
PHOSPHORIBOSYLPYROPH
OSPHATE
AMIDOTRANSFERASE

(Escherichia
coli) 		PF00156
(Pribosyltran)
PF13522
(GATase_6) 		5 ILE A 407
ILE A 425
ALA A 417
LEU A 415
ALA A 412
 None
 1.18A 5zjiB-1ecgA:
undetectable		 5zjiB-1ecgA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fy2 ASPARTYL DIPEPTIDASE

(Salmonella
enterica) 		PF03575
(Peptidase_S51) 		5 ILE A  67
ILE A 130
ALA A 146
LEU A 147
ALA A 107
 None
 1.38A 5zjiB-1fy2A:
undetectable		 5zjiB-1fy2A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i6u 30S RIBOSOMAL
PROTEIN S8P

(Methanocaldococcus
jannaschii) 		PF00410
(Ribosomal_S8) 		5 ILE A 101
ILE A  27
ALA A  10
LEU A  11
ALA A  74
 None
 1.46A 5zjiB-1i6uA:
undetectable		 5zjiB-1i6uA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kzh PHOSPHOFRUCTOKINASE

(Borreliella
burgdorferi) 		PF00365
(PFK) 		5 ILE A 123
ILE A 454
ALA A 169
LEU A 167
ALA A 162
 None
 1.36A 5zjiB-1kzhA:
undetectable		 5zjiB-1kzhA:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n4d VITAMIN B12
TRANSPORT PROTEIN
BTUF

(Escherichia
coli) 		PF01497
(Peripla_BP_2) 		5 ILE A 229
ILE A  20
ALA A  18
LEU A  97
ALA A 114
 None
 1.30A 5zjiB-1n4dA:
2.8		 5zjiB-1n4dA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o9j ALDEHYDE
DEHYDROGENASE,
CYTOSOLIC 1

(Elephantulus
edwardii) 		PF00171
(Aldedh) 		5 ILE A 220
ILE A 126
ALA A  92
LEU A  91
ALA A 211
 None
 1.40A 5zjiB-1o9jA:
undetectable		 5zjiB-1o9jA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qf7 PROTEIN (CATALASE
HPII)

(Escherichia
coli) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		5 ILE A 710
ILE A 672
ALA A 701
LEU A 697
ALA A 696
 None
 1.00A 5zjiB-1qf7A:
undetectable		 5zjiB-1qf7A:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1su7 CARBON MONOXIDE
DEHYDROGENASE 2

(Carboxydothermus
hydrogenoformans) 		PF03063
(Prismane) 		5 ILE A 269
ARG A 389
ILE A 396
ALA A 323
LEU A 324
 None
 1.26A 5zjiB-1su7A:
4.5		 5zjiB-1su7A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfi UNKNOWN PROTEIN

(Arabidopsis
thaliana) 		PF01937
(DUF89) 		5 ILE A 208
ILE A 230
ALA A 234
LEU A 237
ALA A 242
 None
 1.17A 5zjiB-1xfiA:
undetectable		 5zjiB-1xfiA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xwv DER F II

(Dermatophagoides
farinae) 		PF02221
(E1_DerP2_DerF2) 		5 ILE A  68
ILE A  13
ALA A 118
LEU A 110
ALA A  50
 None
None
PE3  A1001 ( 4.7A)
PE3  A1001 ( 4.0A)
None
 1.37A 5zjiB-1xwvA:
undetectable		 5zjiB-1xwvA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y56 HYPOTHETICAL PROTEIN
PH1363

(Pyrococcus
horikoshii) 		PF07992
(Pyr_redox_2)
PF13510
(Fer2_4) 		5 MET A   1
ILE A 270
ALA A 246
LEU A   4
ALA A  37
 None
 1.25A 5zjiB-1y56A:
undetectable		 5zjiB-1y56A:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4m GLYCOGEN
PHOSPHORYLASE

(Corynebacterium
callunae) 		PF00343
(Phosphorylase) 		5 ILE A 544
ILE A 577
ALA A 534
LEU A 538
ALA A 694
 None
 1.31A 5zjiB-2c4mA:
undetectable		 5zjiB-2c4mA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eb0 MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE

(Methanocaldococcus
jannaschii) 		PF01368
(DHH)
PF02833
(DHHA2) 		5 ILE A 125
ILE A 170
ALA A 137
LEU A 140
ALA A  16
 None
 1.30A 5zjiB-2eb0A:
undetectable		 5zjiB-2eb0A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fq1 ISOCHORISMATASE

(Escherichia
coli) 		PF00550
(PP-binding)
PF00857
(Isochorismatase) 		5 ILE A  35
ILE A  17
ALA A 175
LEU A 178
ALA A 153
 None
 1.48A 5zjiB-2fq1A:
undetectable		 5zjiB-2fq1A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ibp CITRATE SYNTHASE

(Pyrobaculum
aerophilum) 		PF00285
(Citrate_synt) 		5 TRP A 375
ILE A 241
ILE A  36
ALA A 377
ALA A 151
 None
 1.33A 5zjiB-2ibpA:
undetectable		 5zjiB-2ibpA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iml HYPOTHETICAL PROTEIN

(Archaeoglobus
fulgidus) 		PF04289
(DUF447) 		5 ILE A  31
ILE A 162
ALA A 139
LEU A 140
ALA A  74
 FMN  A 200 (-3.8A)
None
None
FMN  A 200 (-3.9A)
None
 1.48A 5zjiB-2imlA:
2.5		 5zjiB-2imlA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m26 HCF C-TERMINAL CHAIN
1

(Mus musculus) 		no annotation 5 TRP A  26
ILE A  15
ILE A  36
ALA A 101
ALA A 110
 None
 1.50A 5zjiB-2m26A:
undetectable		 5zjiB-2m26A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qf7 PYRUVATE CARBOXYLASE
PROTEIN

(Rhizobium etli) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF00682
(HMGL-like)
PF02436
(PYC_OADA)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		5 ILE A   3
TRP A  33
ILE A  14
ALA A  15
ALA A  31
 None
 1.47A 5zjiB-2qf7A:
undetectable		 5zjiB-2qf7A:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w4g MYOSIN HEAVY CHAIN,
SKELETAL MUSCLE,
ADULT

(Gallus gallus) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		5 ILE M 443
ILE M 287
ALA M 231
LEU M 228
ALA M 337
 None
 1.36A 5zjiB-2w4gM:
undetectable		 5zjiB-2w4gM:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xij METHYLMALONYL-COA
MUTASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding) 		5 MET A 266
ILE A 446
ALA A 442
LEU A 277
ALA A 273
 None
 1.40A 5zjiB-2xijA:
undetectable		 5zjiB-2xijA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yik ENDOGLUCANASE

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9) 		5 TRP A 136
ILE A 315
ALA A 398
LEU A 401
ALA A 508
 None
 1.08A 5zjiB-2yikA:
undetectable		 5zjiB-2yikA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yn9 POTASSIUM-TRANSPORTI
NG ATPASE ALPHA
CHAIN 1

(Sus scrofa) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF09040
(H-K_ATPase_N)
PF13246
(Cation_ATPase) 		5 ILE A 279
ILE A 758
ALA A 755
LEU A 734
ALA A 737
 None
 1.22A 5zjiB-2yn9A:
4.9		 5zjiB-2yn9A:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yqu 2-OXOGLUTARATE
DEHYDROGENASE E3
COMPONENT

(Thermus
thermophilus) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 ILE A 336
ILE A 284
ALA A 299
LEU A 290
ALA A 320
 None
 1.38A 5zjiB-2yquA:
undetectable		 5zjiB-2yquA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yv3 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Thermus
thermophilus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		5 ILE A 147
TRP A 135
ILE A 217
ALA A 131
LEU A 134
 None
 1.04A 5zjiB-2yv3A:
undetectable		 5zjiB-2yv3A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywb GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]

(Thermus
thermophilus) 		PF00117
(GATase)
PF00958
(GMP_synt_C) 		5 ILE A 176
ILE A  28
ALA A  16
LEU A  19
ALA A  24
 None
 1.19A 5zjiB-2ywbA:
undetectable		 5zjiB-2ywbA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gip N-ACYL-D-GLUTAMATE
DEACYLASE

(Bordetella
bronchiseptica) 		PF07969
(Amidohydro_3) 		5 ILE A 452
ILE A  36
ALA A 426
LEU A 456
ALA A 460
 None
 1.02A 5zjiB-3gipA:
undetectable		 5zjiB-3gipA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5q PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE

(Staphylococcus
aureus) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C) 		5 ILE A 189
MET A 208
ILE A 431
ALA A 234
LEU A 198
 None
 1.31A 5zjiB-3h5qA:
undetectable		 5zjiB-3h5qA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwk METHYLCITRATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF00285
(Citrate_synt) 		5 TRP A 361
ILE A 234
ILE A  42
ALA A 363
ALA A 144
 None
 1.33A 5zjiB-3hwkA:
undetectable		 5zjiB-3hwkA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lmm UNCHARACTERIZED
PROTEIN

(Corynebacterium
diphtheriae) 		PF04326
(AlbA_2)
PF13749
(HATPase_c_4) 		5 ILE A  85
ILE A 113
ALA A  69
LEU A  68
ALA A  64
 None
 1.46A 5zjiB-3lmmA:
undetectable		 5zjiB-3lmmA:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mh9 LIPOPROTEIN LPRG

(Mycobacterium
tuberculosis) 		no annotation 5 ILE C 180
ILE C 160
ALA C 205
LEU C 204
ALA C  48
 None
 1.00A 5zjiB-3mh9C:
undetectable		 5zjiB-3mh9C:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mha LIPOPROTEIN LPRG

(Mycobacterium
tuberculosis) 		PF07161
(LppX_LprAFG) 		5 ILE A 180
ILE A 160
ALA A 205
LEU A 204
ALA A  48
 Z69  A   1 (-4.4A)
None
None
None
None
 0.98A 5zjiB-3mhaA:
undetectable		 5zjiB-3mhaA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nm1 THIAMINE
BIOSYNTHETIC
BIFUNCTIONAL ENZYME

([Candida]
glabrata) 		PF02110
(HK)
PF02581
(TMP-TENI) 		5 ILE A 256
ILE A 502
ALA A 520
LEU A 521
ALA A 285
 None
 1.32A 5zjiB-3nm1A:
undetectable		 5zjiB-3nm1A:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nm1 THIAMINE
BIOSYNTHETIC
BIFUNCTIONAL ENZYME

([Candida]
glabrata) 		PF02110
(HK)
PF02581
(TMP-TENI) 		5 ILE A 472
ILE A 502
ALA A 520
LEU A 521
ALA A 285
 None
 1.44A 5zjiB-3nm1A:
undetectable		 5zjiB-3nm1A:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Clostridioides
difficile) 		PF12683
(DUF3798) 		5 ILE A 389
MET A  55
ILE A 141
ALA A 143
LEU A 334
 None
 1.45A 5zjiB-3qi7A:
undetectable		 5zjiB-3qi7A:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqg 2-METHYLCITRATE
SYNTHASE

(Coxiella
burnetii) 		PF00285
(Citrate_synt) 		5 TRP A 337
ILE A 210
ILE A  18
ALA A 339
ALA A 119
 None
 1.29A 5zjiB-3tqgA:
undetectable		 5zjiB-3tqgA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsd INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Bacillus
anthracis) 		PF00478
(IMPDH)
PF00571
(CBS) 		5 ILE A 302
ILE A 276
ALA A 295
LEU A 290
ALA A 289
 None
 1.15A 5zjiB-3tsdA:
undetectable		 5zjiB-3tsdA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b4u BIFUNCTIONAL PROTEIN
FOLD

(Acinetobacter
baumannii) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		5 ILE A 148
ILE A 187
ALA A 175
LEU A 178
ALA A 183
 None
 1.47A 5zjiB-4b4uA:
undetectable		 5zjiB-4b4uA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bg0 COMPLEMENT
REGULATOR-ACQUIRING
SURFACE PROTEIN 2
(CRASP-2 (CRASP-2)

(Borreliella
burgdorferi) 		no annotation 5 ILE A 136
ILE A 184
ALA A 204
LEU A 207
ALA A 148
 None
 1.15A 5zjiB-4bg0A:
undetectable		 5zjiB-4bg0A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6y CITRATE SYNTHASE

(Vibrio
vulnificus) 		PF00285
(Citrate_synt) 		5 TRP A 392
ILE A 257
ILE A  57
ALA A 394
ALA A 162
 None
 1.39A 5zjiB-4e6yA:
undetectable		 5zjiB-4e6yA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxh PYRROLIDONE-CARBOXYL
ATE PEPTIDASE

(Xenorhabdus
bovienii) 		PF01470
(Peptidase_C15) 		5 ILE A   4
ILE A 130
ALA A 192
LEU A 193
ALA A  23
 None
 1.30A 5zjiB-4gxhA:
undetectable		 5zjiB-4gxhA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hb9 SIMILARITIES WITH
PROBABLE
MONOOXYGENASE

(Photorhabdus
laumondii) 		PF01494
(FAD_binding_3) 		5 ILE A   5
ILE A  44
ALA A 330
LEU A 334
ALA A  53
 None
FAD  A 501 (-4.4A)
FAD  A 501 (-3.3A)
None
None
 1.41A 5zjiB-4hb9A:
undetectable		 5zjiB-4hb9A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hum MULTIDRUG EFFLUX
PROTEIN

(Neisseria
gonorrhoeae) 		PF01554
(MatE) 		5 ILE A 254
TRP A 211
ILE A 169
ALA A 158
LEU A 156
 None
 1.38A 5zjiB-4humA:
2.0		 5zjiB-4humA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A

(Mus musculus) 		PF13516
(LRR_6) 		5 MET A 627
ILE A 615
ALA A 592
LEU A 595
ALA A 598
 None
 1.46A 5zjiB-4k17A:
undetectable		 5zjiB-4k17A:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l5f HEAVY CHAIN OF E106
ANTIBODY (VH AND CH1
OF IGG2C)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		5 TRP H 103
TRP H  98
ILE H  34
LEU H 100
ALA H  99
 None
 1.47A 5zjiB-4l5fH:
undetectable		 5zjiB-4l5fH:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lxr PROTEIN TOLL

(Drosophila
melanogaster) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13306
(LRR_5)
PF13855
(LRR_8) 		5 ILE A 648
TRP A 723
ILE A 707
LEU A 699
ALA A 700
 None
 1.33A 5zjiB-4lxrA:
undetectable		 5zjiB-4lxrA:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nvr PUTATIVE
ACYLTRANSFERASE

(Salmonella
enterica) 		PF00561
(Abhydrolase_1) 		5 ILE A  67
ILE A 242
ALA A 126
LEU A 125
ALA A  95
 None
 1.50A 5zjiB-4nvrA:
undetectable		 5zjiB-4nvrA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4onu ACETYLTRANSFERASE
PAT

(Mycolicibacterium
smegmatis) 		PF00027
(cNMP_binding)
PF13302
(Acetyltransf_3) 		5 TRP A 108
ILE A 106
ALA A  30
LEU A  12
ALA A  13
 None
 1.47A 5zjiB-4onuA:
undetectable		 5zjiB-4onuA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ow1 RESUSCITATION-PROMOT
ING FACTOR RPFC

(Mycobacterium
tuberculosis) 		PF06737
(Transglycosylas) 		5 ILE A  81
ILE A  55
ALA A  58
LEU A  62
ALA A  63
 None
 1.27A 5zjiB-4ow1A:
undetectable		 5zjiB-4ow1A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q1t GLUTAMATE 5-KINASE

(Burkholderia
thailandensis) 		PF00696
(AA_kinase)
PF01472
(PUA) 		5 ILE A 222
ILE A   5
ALA A 168
LEU A 169
ALA A 161
 None
 1.37A 5zjiB-4q1tA:
undetectable		 5zjiB-4q1tA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qjy GH127
BETA-L-ARABINOFURANO
SIDASE

(Geobacillus
stearothermophilus) 		PF07944
(Glyco_hydro_127) 		5 ILE A 332
ILE A 142
ALA A 191
LEU A 190
ALA A 269
 None
 1.44A 5zjiB-4qjyA:
undetectable		 5zjiB-4qjyA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qjy GH127
BETA-L-ARABINOFURANO
SIDASE

(Geobacillus
stearothermophilus) 		PF07944
(Glyco_hydro_127) 		5 TRP A  76
ILE A  40
ALA A  35
LEU A  36
ALA A  48
 None
None
ACT  A 704 ( 3.7A)
None
None
 1.46A 5zjiB-4qjyA:
undetectable		 5zjiB-4qjyA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT

(Actinobacillus
pleuropneumoniae) 		PF13343
(SBP_bac_6) 		5 ILE A 186
TRP A 262
ALA A 282
LEU A 268
ALA A 267
 GOL  A 401 (-4.6A)
None
None
None
None
 1.49A 5zjiB-4r72A:
undetectable		 5zjiB-4r72A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7z CELL DIVISION
CONTROL PROTEIN 21

(Pyrococcus
furiosus) 		PF00493
(MCM) 		5 ILE A 866
ILE A 322
ALA A 303
LEU A 304
ALA A 345
 None
 1.47A 5zjiB-4r7zA:
undetectable		 5zjiB-4r7zA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1

(Pisum sativum) 		PF00223
(PsaA_PsaB) 		7 TRP A  55
MET A 691
ARG A 697
TRP A 700
ILE A 704
ALA A 724
LEU A 725
 CLA  A1139 (-4.1A)
CLA  A9013 ( 3.6A)
None
PQN  A5001 ( 3.4A)
CLA  A1139 ( 4.5A)
PQN  A5001 (-3.4A)
PQN  A5001 ( 3.7A)
 0.66A 5zjiB-4rkuA:
40.2		 5zjiB-4rkuA:
7.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Pisum sativum) 		PF00223
(PsaA_PsaB) 		10 TRP B  22
ILE B  25
MET B 662
TRP B 667
ARG B 668
TRP B 671
ILE B 675
ALA B 699
LEU B 700
ALA B 705
 CLA  B1238 ( 4.0A)
CLA  B1201 ( 4.7A)
CLA  B9023 ( 3.3A)
None
None
PQN  B5002 ( 3.3A)
CLA  B1238 (-3.9A)
PQN  B5002 (-3.2A)
PQN  B5002 (-3.7A)
PQN  B5002 (-3.4A)
 0.56A 5zjiB-4rkuB:
46.0		 5zjiB-4rkuB:
94.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wer DIACYLGLYCEROL
KINASE CATALYTIC
DOMAIN PROTEIN

(Enterococcus
faecalis) 		PF00781
(DAGK_cat) 		5 MET A 133
ILE A   7
ALA A  50
LEU A  77
ALA A  78
 None
 1.20A 5zjiB-4werA:
undetectable		 5zjiB-4werA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y7d ALPHA/BETA HYDROLASE
FOLD PROTEIN

(Nakamurella
multipartita) 		PF00561
(Abhydrolase_1) 		5 ILE A  61
ILE A 235
ALA A 114
LEU A 113
ALA A  83
 None
 1.49A 5zjiB-4y7dA:
undetectable		 5zjiB-4y7dA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z26 PUTATIVE GMC-TYPE
OXIDOREDUCTASE R135

(Acanthamoeba
polyphaga
mimivirus) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		5 ILE A  33
MET A 285
ILE A 306
LEU A  36
ALA A 261
 None
 1.33A 5zjiB-4z26A:
undetectable		 5zjiB-4z26A:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zh7 OUTER MEMBRANE
PROTEIN-ADHESIN

(Helicobacter
pylori) 		no annotation 6 TRP A  97
ILE A 133
ILE A 311
ALA A  93
LEU A 269
ALA A 159
 None
 1.08A 5zjiB-4zh7A:
undetectable		 5zjiB-4zh7A:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5abm RETINAL
DEHYDROGENASE 1

(Ovis aries) 		PF00171
(Aldedh) 		5 ILE A 220
ILE A 126
ALA A  92
LEU A  91
ALA A 211
 None
 1.34A 5zjiB-5abmA:
undetectable		 5zjiB-5abmA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aw4 NA, K-ATPASE ALPHA
SUBUNIT

(Squalus
acanthias) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF13246
(Cation_ATPase) 		5 ILE A 270
ILE A 749
ALA A 746
LEU A 725
ALA A 728
 None
None
None
None
K  A2007 ( 4.5A)
 1.21A 5zjiB-5aw4A:
undetectable		 5zjiB-5aw4A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cyu CONSERVED MEMBRANE
PROTEIN

(Mycolicibacterium
smegmatis) 		PF05108
(T7SS_ESX1_EccB) 		5 ILE A 169
ILE A 176
ALA A 175
LEU A 371
ALA A 375
 None
 1.36A 5zjiB-5cyuA:
undetectable		 5zjiB-5cyuA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dkx ALPHA
GLUCOSIDASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF17137
(DUF5110) 		5 TRP A 335
ILE A 333
TRP A 141
ALA A 339
ALA A 138
 None
 1.49A 5zjiB-5dkxA:
undetectable		 5zjiB-5dkxA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eeb ALDEHYDE
DEHYDROGENASE

(Pyrobaculum
ferrireducens) 		PF00171
(Aldedh) 		5 ILE A  65
ILE A 165
ALA A 166
LEU A  74
ALA A 118
 None
 1.28A 5zjiB-5eebA:
undetectable		 5zjiB-5eebA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9a ADHESIN BINDING
FUCOSYLATED
HISTO-BLOOD GROUP
ANTIGEN,ADHESIN,ADHE
SIN BINDING
FUCOSYLATED
HISTO-BLOOD GROUP
ANTIGEN

(Helicobacter
pylori) 		no annotation 6 TRP A  97
ILE A 133
ILE A 305
ALA A  93
LEU A 266
ALA A 159
 None
 1.10A 5zjiB-5f9aA:
undetectable		 5zjiB-5f9aA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fhz ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3

(Homo sapiens) 		PF00171
(Aldedh) 		5 ILE A 232
ILE A 138
ALA A 104
LEU A 103
ALA A 223
 None
 1.36A 5zjiB-5fhzA:
undetectable		 5zjiB-5fhzA:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdi CYTOCHROME P450 144

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		5 TRP A 171
ILE A 169
ILE A 312
LEU A 284
ALA A 281
 None
 1.41A 5zjiB-5hdiA:
undetectable		 5zjiB-5hdiA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jja SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
56 KDA REGULATORY
SUBUNIT GAMMA
ISOFORM

(Homo sapiens) 		PF01603
(B56) 		5 ILE A 311
ILE A 369
ALA A 332
LEU A 331
ALA A 346
 ILE  A 311 ( 0.6A)
ILE  A 369 ( 0.7A)
ALA  A 332 ( 0.0A)
LEU  A 331 ( 0.6A)
ALA  A 346 ( 0.0A)
 1.42A 5zjiB-5jjaA:
undetectable		 5zjiB-5jjaA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mso CARBOXYLIC ACID
REDUCTASE

(Mycobacterium
marinum) 		PF07993
(NAD_binding_4) 		5 ILE A 877
ILE A1041
ALA A1042
LEU A 794
ALA A 795
 None
 1.20A 5zjiB-5msoA:
undetectable		 5zjiB-5msoA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nz7 CELLODEXTRIN
PHOSPHORYLASE

(Ruminiclostridium
thermocellum) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		5 ILE A 607
ILE A 705
ALA A 668
LEU A 671
ALA A 674
 None
 1.43A 5zjiB-5nz7A:
undetectable		 5zjiB-5nz7A:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1

(Homo sapiens) 		no annotation 5 ILE A 124
TRP A 154
ILE A  70
ALA A 153
ALA A 158
 9P2  A 401 (-4.4A)
None
TLA  A 402 (-3.3A)
OLA  A 404 ( 4.0A)
OLA  A 416 (-3.5A)
 1.43A 5zjiB-5o9hA:
2.1		 5zjiB-5o9hA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oc1 ARYL-ALCOHOL OXIDASE

(Pleurotus
eryngii) 		no annotation 5 ILE A 156
ILE A 391
ALA A 358
LEU A 356
ALA A 355
 None
ANN  A 601 (-3.9A)
ANN  A 601 ( 4.9A)
None
None
 1.27A 5zjiB-5oc1A:
undetectable		 5zjiB-5oc1A:
9.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1

(Synechocystis
sp. PCC 6803) 		no annotation 7 TRP 1  49
MET 1 684
ARG 1 690
TRP 1 693
ILE 1 697
ALA 1 717
LEU 1 718
 CLA  1 840 (-4.7A)
CLA  1 802 ( 3.2A)
None
PQN  1 842 ( 3.3A)
None
PQN  1 842 (-3.2A)
PQN  1 842 ( 3.6A)
 0.57A 5zjiB-5oy01:
37.4		 5zjiB-5oy01:
32.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Synechocystis
sp. PCC 6803) 		no annotation 6 ILE b  21
MET b 659
TRP b 664
TRP b 668
LEU b 697
ALA b 702
 None
CLA  b1807 ( 3.2A)
None
PQN  b1844 ( 3.4A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 1.44A 5zjiB-5oy0b:
44.3		 5zjiB-5oy0b:
78.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Synechocystis
sp. PCC 6803) 		no annotation 10 TRP b  22
ILE b  25
MET b 659
TRP b 664
ARG b 665
TRP b 668
ILE b 672
ALA b 696
LEU b 697
ALA b 702
 CLA  b1841 ( 4.0A)
LMG  b1851 ( 4.9A)
CLA  b1807 ( 3.2A)
None
None
PQN  b1844 ( 3.4A)
CLA  b1841 (-4.6A)
PQN  b1844 (-3.2A)
PQN  b1844 ( 3.8A)
PQN  b1844 (-3.1A)
 0.37A 5zjiB-5oy0b:
44.3		 5zjiB-5oy0b:
78.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4h UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Acinetobacter
baumannii) 		PF00275
(EPSP_synthase) 		5 ILE A  33
ILE A 192
ALA A 196
LEU A 199
ALA A 204
 None
 1.33A 5zjiB-5u4hA:
undetectable		 5zjiB-5u4hA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ui2 ORANGE
CAROTENOID-BINDING
PROTEIN

(Arthrospira
maxima) 		PF02136
(NTF2)
PF09150
(Carot_N) 		5 ILE A  25
ILE A 125
ALA A  38
LEU A  39
ALA A 135
 None
 1.20A 5zjiB-5ui2A:
undetectable		 5zjiB-5ui2A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v4f PUTATIVE
TRANSLATIONAL
INHIBITOR PROTEIN

(Yersinia pestis) 		PF01042
(Ribonuc_L-PSP) 		5 ILE A  94
ILE A  33
ALA A 129
LEU A  79
ALA A 108
 None
 1.25A 5zjiB-5v4fA:
undetectable		 5zjiB-5v4fA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vqi IMPORTIN SUBUNIT
ALPHA

(Neurospora
crassa) 		no annotation 5 ILE B 269
ILE B 249
ALA B 252
LEU B 256
ALA B 257
 None
 1.22A 5zjiB-5vqiB:
1.9		 5zjiB-5vqiB:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wi5 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1

(Streptococcus
pneumoniae) 		PF00275
(EPSP_synthase) 		5 ILE A  34
ILE A 195
ALA A 199
LEU A 202
ALA A 207
 None
 1.34A 5zjiB-5wi5A:
undetectable		 5zjiB-5wi5A:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA

(Escherichia
coli;
Homo sapiens) 		no annotation 5 ILE B 210
TRP B 240
ILE B 156
ALA B 239
ALA B 244
 9P2  B 501 (-4.3A)
None
None
None
None
 1.25A 5zjiB-6c1qB:
2.6		 5zjiB-6c1qB:
13.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1

(Cyanidioschyzon
merolae) 		no annotation 5 MET A 681
ARG A 687
TRP A 690
ILE A 694
ALA A 714
 PQN  A2001 ( 3.3A)
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
 0.78A 5zjiB-6fosA:
34.2		 5zjiB-6fosA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1

(Cyanidioschyzon
merolae) 		no annotation 5 MET A 681
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 PQN  A2001 ( 3.3A)
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.65A 5zjiB-6fosA:
34.2		 5zjiB-6fosA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1

(Cyanidioschyzon
merolae) 		no annotation 5 TRP A  46
ARG A 687
TRP A 690
ILE A 694
ALA A 714
 None
None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
 0.74A 5zjiB-6fosA:
34.2		 5zjiB-6fosA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1

(Cyanidioschyzon
merolae) 		no annotation 5 TRP A  46
TRP A 690
ILE A 694
ALA A 714
LEU A 715
 None
PQN  A2001 ( 3.2A)
None
PQN  A2001 (-3.2A)
PQN  A2001 (-3.7A)
 0.51A 5zjiB-6fosA:
34.2		 5zjiB-6fosA:
34.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Cyanidioschyzon
merolae) 		no annotation 8 ILE B  25
MET B 660
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 CLA  B1201 ( 4.6A)
PQN  B2002 ( 3.2A)
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.68A 5zjiB-6fosB:
32.7		 5zjiB-6fosB:
83.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Cyanidioschyzon
merolae) 		no annotation 5 ILE B 125
TRP B  70
ALA B 137
LEU B 133
ALA B  69
 None
 1.43A 5zjiB-6fosB:
32.7		 5zjiB-6fosB:
83.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Cyanidioschyzon
merolae) 		no annotation 9 TRP B  22
ILE B  25
TRP B 665
ARG B 666
TRP B 669
ILE B 673
ALA B 697
LEU B 698
ALA B 703
 None
CLA  B1201 ( 4.6A)
None
None
PQN  B2002 (-3.3A)
None
PQN  B2002 (-3.1A)
PQN  B2002 (-3.6A)
PQN  B2002 (-3.4A)
 0.94A 5zjiB-6fosB:
32.7		 5zjiB-6fosB:
83.56