SIMILAR PATTERNS OF AMINO ACIDS FOR 5Z6K_A_FOLA201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13pk 3-PHOSPHOGLYCERATE
KINASE

(Trypanosoma
brucei) 		PF00162
(PGK) 		3 MET A 177
ASP A  24
ARG A  65
 None
3PG  A 423 (-2.7A)
3PG  A 423 (-4.3A)
 1.13A 5z6kA-13pkA:
1.1		 5z6kA-13pkA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a88 CHLOROPEROXIDASE L

(Streptomyces
lividans) 		PF00561
(Abhydrolase_1) 		3 MET A  41
ASP A  35
ARG A  56
 None
 1.04A 5z6kA-1a88A:
1.5		 5z6kA-1a88A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1crk CREATINE KINASE

(Gallus gallus) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		3 MET A 202
ASP A 228
ARG A  91
 None
 1.03A 5z6kA-1crkA:
0.0		 5z6kA-1crkA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hdi PHOSPHOGLYCERATE
KINASE

(Sus scrofa) 		PF00162
(PGK) 		3 MET A 175
ASP A  23
ARG A  65
 None
3PG  A 419 (-2.9A)
3PG  A 419 (-4.0A)
 1.11A 5z6kA-1hdiA:
0.0		 5z6kA-1hdiA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqo PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Zea mays) 		PF00311
(PEPcase) 		3 MET A 327
ASP A 380
ARG A 342
 None
 1.14A 5z6kA-1jqoA:
0.0		 5z6kA-1jqoA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lrw METHANOL
DEHYDROGENASE
SUBUNIT 1

(Paracoccus
denitrificans) 		PF01011
(PQQ)
PF13360
(PQQ_2) 		3 MET A 278
ASP A 303
ARG A 109
 None
CA  A 702 (-3.4A)
PQQ  A 701 (-3.5A)
 1.19A 5z6kA-1lrwA:
undetectable		 5z6kA-1lrwA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nvm 4-HYDROXY-2-OXOVALER
ATE ALDOLASE

(Pseudomonas sp.
CF600) 		PF00682
(HMGL-like)
PF07836
(DmpG_comm) 		3 MET A 184
ASP A 221
ARG A 111
 None
 1.20A 5z6kA-1nvmA:
0.0		 5z6kA-1nvmA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1po0 IRON(III) DICITRATE
TRANSPORT PROTEIN
FECA PRECURSOR

(Escherichia
coli) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 MET A 189
ASP A 165
ARG A 337
 None
 1.17A 5z6kA-1po0A:
undetectable		 5z6kA-1po0A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pqu ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Haemophilus
influenzae) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		3 MET A 143
ASP A 113
ARG A  20
 None
 1.08A 5z6kA-1pquA:
0.0		 5z6kA-1pquA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qxo CHORISMATE SYNTHASE

(Streptococcus
pneumoniae) 		PF01264
(Chorismate_synt) 		3 MET A  88
ASP A 123
ARG A 107
 None
None
EPS  A5001 ( 4.4A)
 1.20A 5z6kA-1qxoA:
undetectable		 5z6kA-1qxoA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Escherichia
coli) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		3 MET A 142
ASP A 112
ARG A  20
 None
 1.12A 5z6kA-1t4bA:
undetectable		 5z6kA-1t4bA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wue MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN

(Enterococcus
faecalis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 MET A1187
ASP A1316
ARG A1266
 None
 1.07A 5z6kA-1wueA:
undetectable		 5z6kA-1wueA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0v METHANOL
DEHYDROGENASE LARGE
SUBUNIT

(Hyphomicrobium
denitrificans) 		PF01011
(PQQ)
PF13360
(PQQ_2) 		3 MET A 278
ASP A 303
ARG A 109
 None
CA  A 775 ( 3.4A)
PQQ  A 601 (-3.2A)
 1.22A 5z6kA-2d0vA:
undetectable		 5z6kA-2d0vA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3i OVOTRANSFERRIN

(Gallus gallus) 		PF00405
(Transferrin) 		3 MET A 679
ASP A 315
ARG A 597
 None
 1.20A 5z6kA-2d3iA:
undetectable		 5z6kA-2d3iA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fqz R.ECL18KI

(Enterobacter
cloacae) 		PF09019
(EcoRII-C) 		3 MET A 204
ASP A 160
ARG A 188
 None
 1.02A 5z6kA-2fqzA:
undetectable		 5z6kA-2fqzA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gam BETA-1,6-N-ACETYLGLU
COSAMINYLTRANSFERASE

(Mus musculus) 		PF02485
(Branch) 		3 MET A  96
ASP A 137
ARG A  87
 None
 1.20A 5z6kA-2gamA:
undetectable		 5z6kA-2gamA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h1n OLIGOENDOPEPTIDASE F

(Geobacillus
stearothermophilus) 		PF01432
(Peptidase_M3) 		3 MET A 272
ASP A 416
ARG A 181
 None
 1.09A 5z6kA-2h1nA:
undetectable		 5z6kA-2h1nA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hwx TELOMERASE-BINDING
PROTEIN EST1A

(Homo sapiens) 		PF13638
(PIN_4) 		3 MET A1239
ASP A1366
ARG A1244
 None
 1.16A 5z6kA-2hwxA:
undetectable		 5z6kA-2hwxA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2if7 SLAM FAMILY MEMBER 6

(Homo sapiens) 		PF07686
(V-set) 		3 MET A  79
ASP A 137
ARG A 109
 None
 1.10A 5z6kA-2if7A:
undetectable		 5z6kA-2if7A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8s AGR_C_984P

(Agrobacterium
fabrum) 		PF06748
(DUF1217) 		3 MET A 120
ASP A 147
ARG A 204
 None
 1.22A 5z6kA-2o8sA:
undetectable		 5z6kA-2o8sA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ols PHOSPHOENOLPYRUVATE
SYNTHASE

(Neisseria
meningitidis) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		3 MET A 679
ASP A 582
ARG A 715
 None
 1.21A 5z6kA-2olsA:
undetectable		 5z6kA-2olsA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vrs SIGMA-C CAPSID
PROTEIN

(Avian
orthoreovirus) 		PF04582
(Reo_sigmaC) 		3 MET A 198
ASP A 259
ARG A 299
 None
None
GOL  A1327 (-3.9A)
 0.94A 5z6kA-2vrsA:
undetectable		 5z6kA-2vrsA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu8 GLUCOSE-6-PHOSPHATE
ISOMERASE

(Mycobacterium
tuberculosis) 		PF00342
(PGI) 		3 MET A 284
ASP A 134
ARG A 107
 None
 1.22A 5z6kA-2wu8A:
undetectable		 5z6kA-2wu8A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z5x AMINE OXIDASE
[FLAVIN-CONTAINING]
A

(Homo sapiens) 		PF01593
(Amino_oxidase) 		3 MET A 445
ASP A  64
ARG A  45
 FAD  A 600 (-4.3A)
GOL  A 702 (-3.6A)
FAD  A 600 ( 3.8A)
 1.08A 5z6kA-2z5xA:
undetectable		 5z6kA-2z5xA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwz BETA-LACTAMASE

(Mycobacterium
tuberculosis) 		PF13354
(Beta-lactamase2) 		3 MET A 129
ASP A 143
ARG A 115
 None
None
PO4  A   2 ( 4.4A)
 1.15A 5z6kA-3dwzA:
undetectable		 5z6kA-3dwzA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3esh PROTEIN SIMILAR TO
METAL-DEPENDENT
HYDROLASE

(Staphylococcus
aureus) 		PF00753
(Lactamase_B) 		3 MET A  23
ASP A 206
ARG A 273
 None
 1.15A 5z6kA-3eshA:
undetectable		 5z6kA-3eshA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3faw RETICULOCYTE BINDING
PROTEIN

(Streptococcus
agalactiae) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		3 MET A 702
ASP A 673
ARG A 676
 None
 1.13A 5z6kA-3fawA:
undetectable		 5z6kA-3fawA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fzp PROTEIN TYROSINE
KINASE 2 BETA

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 MET A 610
ASP A 549
ARG A 600
 None
 1.21A 5z6kA-3fzpA:
undetectable		 5z6kA-3fzpA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3he0 TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Vibrio
parahaemolyticus) 		PF00440
(TetR_N)
PF16295
(TetR_C_10) 		3 MET A  31
ASP A  51
ARG A  60
 None
 1.07A 5z6kA-3he0A:
undetectable		 5z6kA-3he0A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hea ARYLESTERASE

(Pseudomonas
fluorescens) 		PF00561
(Abhydrolase_1) 		3 MET A  39
ASP A  33
ARG A  54
 None
 1.07A 5z6kA-3heaA:
undetectable		 5z6kA-3heaA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hps 2-ISOPROPYLMALATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF00682
(HMGL-like)
PF08502
(LeuA_dimer) 		3 MET A  90
ASP A  78
ARG A 104
 None
 1.21A 5z6kA-3hpsA:
undetectable		 5z6kA-3hpsA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA

(Moorella
thermoacetica) 		PF03063
(Prismane) 		3 MET A 561
ASP A 570
ARG A 199
 None
 1.09A 5z6kA-3i04A:
undetectable		 5z6kA-3i04A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4p TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY

(Agrobacterium
fabrum) 		PF01037
(AsnC_trans_reg)
PF13412
(HTH_24) 		3 MET A  41
ASP A   2
ARG A  10
 None
 1.14A 5z6kA-3i4pA:
undetectable		 5z6kA-3i4pA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3if9 GLYCINE OXIDASE

(Bacillus
subtilis) 		PF01266
(DAO) 		3 MET A 111
ASP A 145
ARG A 329
 None
None
GOA  A 370 ( 3.1A)
 1.16A 5z6kA-3if9A:
undetectable		 5z6kA-3if9A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7g XAA-PRO DIPEPTIDASE

(Alteromonas sp.) 		PF00557
(Peptidase_M24) 		3 MET A 168
ASP A 344
ARG A  18
 None
 1.00A 5z6kA-3l7gA:
undetectable		 5z6kA-3l7gA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l88 FIBER PROTEIN

(Human
mastadenovirus
B) 		PF00541
(Adeno_knob) 		3 MET A 184
ASP A 154
ARG A 195
 None
 0.97A 5z6kA-3l88A:
undetectable		 5z6kA-3l88A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n05 NH(3)-DEPENDENT
NAD(+) SYNTHETASE

(Streptomyces
avermitilis) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		3 MET A 146
ASP A 271
ARG A 205
 None
 1.15A 5z6kA-3n05A:
undetectable		 5z6kA-3n05A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pfi HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB

(Campylobacter
jejuni) 		PF05491
(RuvB_C)
PF05496
(RuvB_N) 		3 MET A 163
ASP A 289
ARG A 314
 None
 1.13A 5z6kA-3pfiA:
undetectable		 5z6kA-3pfiA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvt PHENYLACETIC ACID
DEGRADATION PROTEIN
PAAA

(Escherichia
coli) 		PF05138
(PaaA_PaaC) 		3 MET A 193
ASP A 260
ARG A 271
 None
 1.01A 5z6kA-3pvtA:
undetectable		 5z6kA-3pvtA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pzr ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Vibrio cholerae) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		3 MET A 141
ASP A 111
ARG A  19
 None
 1.07A 5z6kA-3pzrA:
undetectable		 5z6kA-3pzrA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rc2 SUGAR
3-KETOREDUCTASE

(Actinomadura
kijaniata) 		PF01408
(GFO_IDH_MocA) 		3 MET A 236
ASP A 182
ARG A  23
 None
NAP  A 336 (-3.5A)
TLO  A 335 ( 2.5A)
 1.22A 5z6kA-3rc2A:
undetectable		 5z6kA-3rc2A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tad LIPRIN-ALPHA-2

(Homo sapiens) 		PF00536
(SAM_1)
PF07647
(SAM_2) 		3 MET A 913
ASP A1047
ARG A 955
 None
 1.15A 5z6kA-3tadA:
undetectable		 5z6kA-3tadA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uw3 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Burkholderia
thailandensis) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		3 MET A 141
ASP A 111
ARG A  19
 None
None
EDO  A 374 ( 4.9A)
 1.11A 5z6kA-3uw3A:
undetectable		 5z6kA-3uw3A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3va8 PROBABLE DEHYDRATASE

(Fusarium
graminearum) 		PF13378
(MR_MLE_C) 		3 MET A 269
ASP A 220
ARG A 422
 None
MG  A 425 ( 2.4A)
None
 1.18A 5z6kA-3va8A:
undetectable		 5z6kA-3va8A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vu4 KMHSV2

(Kluyveromyces
marxianus) 		no annotation 3 MET A 195
ASP A 240
ARG A  60
 None
 1.02A 5z6kA-3vu4A:
undetectable		 5z6kA-3vu4A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfz LACTO-N-BIOSE
PHOSPHORYLASE

(Bifidobacterium
longum) 		PF09508
(Lact_bio_phlase)
PF17385
(LBP_M)
PF17386
(LBP_C) 		3 MET A 450
ASP A 283
ARG A 275
 None
 0.98A 5z6kA-3wfzA:
undetectable		 5z6kA-3wfzA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ze7 PERIPLASMIC [NIFESE]
HYDROGENASE, LARGE
SUBUNIT,
SELENOCYSTEINE-CONTA
INING

(Desulfovibrio
vulgaris) 		PF00374
(NiFeSe_Hases) 		3 MET B 235
ASP B 147
ARG B  26
 None
 1.19A 5z6kA-3ze7B:
undetectable		 5z6kA-3ze7B:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zo9 TREHALOSE
SYNTHASE/AMYLASE
TRES

(Mycolicibacterium
smegmatis) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 MET A 348
ASP A 355
ARG A 312
 None
 1.17A 5z6kA-3zo9A:
undetectable		 5z6kA-3zo9A:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aah METHANOL
DEHYDROGENASE

(Methylophilus
methylotrophus) 		PF13360
(PQQ_2) 		3 MET A 272
ASP A 297
ARG A 109
 None
CA  A 702 (-3.6A)
PQQ  A 701 (-3.6A)
 1.14A 5z6kA-4aahA:
undetectable		 5z6kA-4aahA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4crs SERINE/THREONINE-PRO
TEIN KINASE N2

(Homo sapiens) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		3 MET A 973
ASP A 700
ARG A 696
 None
 1.11A 5z6kA-4crsA:
undetectable		 5z6kA-4crsA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyo ASPARTYL
AMINOPEPTIDASE

(Homo sapiens) 		PF02127
(Peptidase_M18) 		3 MET A 439
ASP A 346
ARG A 380
 SD4  A 504 ( 3.7A)
ZN  A 502 ( 2.0A)
None
 1.13A 5z6kA-4dyoA:
undetectable		 5z6kA-4dyoA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eo4 THREONINE--TRNA
LIGASE,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon) 		3 MET A 277
ASP A 266
ARG A 162
 None
None
SSA  A1001 (-2.8A)
 0.78A 5z6kA-4eo4A:
undetectable		 5z6kA-4eo4A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsb PROBABLE
DNA-3-METHYLADENINE
GLYCOSYLASE 2

(Schizosaccharomyces
pombe) 		PF00730
(HhH-GPD) 		3 MET A 130
ASP A 161
ARG A 195
 None
 1.22A 5z6kA-4hsbA:
undetectable		 5z6kA-4hsbA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kp2 HOMOACONITASE LARGE
SUBUNIT

(Methanocaldococcus
jannaschii) 		PF00330
(Aconitase) 		3 MET A  30
ASP A  61
ARG A 385
 None
 1.02A 5z6kA-4kp2A:
undetectable		 5z6kA-4kp2A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lxf TREHALOSE SYNTHASE

(Mycobacterium
tuberculosis) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 MET A 356
ASP A 363
ARG A 320
 None
 1.01A 5z6kA-4lxfA:
undetectable		 5z6kA-4lxfA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nav HYPOTHETICAL PROTEIN
XCC279

(Xanthomonas
campestris) 		no annotation 3 MET D 116
ASP D  52
ARG D 151
 None
 0.84A 5z6kA-4navD:
2.9		 5z6kA-4navD:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oqj PKS

(Streptomyces
albus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 MET A 211
ASP A 273
ARG A 504
 None
 0.88A 5z6kA-4oqjA:
undetectable		 5z6kA-4oqjA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1e TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Escherichia
fergusonii) 		PF03480
(DctP) 		3 MET A 281
ASP A  40
ARG A 152
 None
 1.06A 5z6kA-4p1eA:
undetectable		 5z6kA-4p1eA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4p68 DIHYDROFOLATE
REDUCTASE

(Escherichia
coli) 		PF00186
(DHFR_1) 		3 MET A  20
ASP A  27
ARG A  57
 MTX  A 201 ( 3.6A)
MTX  A 201 (-3.0A)
MTX  A 201 (-3.0A)
 0.64A 5z6kA-4p68A:
30.2		 5z6kA-4p68A:
98.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pel PENICILLIN G ACYLASE
SUBUNIT ALPHA
PENICILLIN G ACYLASE
SUBUNIT BETA

(Kluyvera
cryocrescens;
Kluyvera
cryocrescens) 		PF01804
(Penicil_amidase)
PF01804
(Penicil_amidase) 		3 MET B 527
ASP B 501
ARG A  39
 None
 0.93A 5z6kA-4pelB:
undetectable		 5z6kA-4pelB:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6u UNCHARACTERIZED
PROTEIN

(Mycobacterium
tuberculosis) 		no annotation 3 MET A  75
ASP A 114
ARG A 109
 None
1PE  A 401 (-3.2A)
None
 0.84A 5z6kA-4q6uA:
undetectable		 5z6kA-4q6uA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qyr AT-LESS POLYKETIDE
SYNTHASE

(Streptomyces
platensis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 MET A2732
ASP A2794
ARG A3037
 None
 0.97A 5z6kA-4qyrA:
undetectable		 5z6kA-4qyrA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqo METHANOL
DEHYDROGENASE
PROTEIN, LARGE
SUBUNIT

(Methylococcus
capsulatus) 		no annotation 3 MET B 306
ASP B 331
ARG B 137
 None
CA  B 701 ( 3.1A)
PQQ  B 702 (-3.0A)
 1.19A 5z6kA-4tqoB:
undetectable		 5z6kA-4tqoB:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5u CHITINASE

(Streptomyces
thermoviolaceus) 		no annotation 3 MET B 204
ASP B 179
ARG B 383
 None
 0.82A 5z6kA-4w5uB:
undetectable		 5z6kA-4w5uB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w87 XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE

(uncultured
bacterium) 		PF00150
(Cellulase) 		3 MET A 187
ASP A 139
ARG A 174
 None
 1.19A 5z6kA-4w87A:
undetectable		 5z6kA-4w87A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wfi CUTINASE

(Saccharomonospora
viridis) 		PF03403
(PAF-AH_p_II) 		3 MET A 247
ASP A 292
ARG A 119
 None
 0.88A 5z6kA-4wfiA:
undetectable		 5z6kA-4wfiA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wky BETA-KETOACYL
SYNTHASE

(Streptomyces
albus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 MET A 211
ASP A 273
ARG A 500
 None
 0.87A 5z6kA-4wkyA:
undetectable		 5z6kA-4wkyA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yu5 IMMUNE INHIBITOR A,
METALLOPROTEASE

(Bacillus cereus) 		PF05547
(Peptidase_M6) 		3 MET A 437
ASP A 164
ARG A 292
 None
 1.21A 5z6kA-4yu5A:
undetectable		 5z6kA-4yu5A:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yyf BETA-N-ACETYLHEXOSAM
INIDASE

(Mycolicibacterium
smegmatis) 		PF00933
(Glyco_hydro_3) 		3 MET A  94
ASP A 313
ARG A 195
 None
None
ACT  A 401 (-2.8A)
 1.10A 5z6kA-4yyfA:
undetectable		 5z6kA-4yyfA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z37 PUTATIVE MIXED
POLYKETIDE
SYNTHASE/NON-RIBOSOM
AL PEPTIDE
SYNTHETASE

(Brevibacillus
brevis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 MET A2884
ASP A2903
ARG A2827
 None
 1.09A 5z6kA-4z37A:
undetectable		 5z6kA-4z37A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z7g SERINE/THREONINE-PRO
TEIN
KINASE/ENDORIBONUCLE
ASE IRE1

(Homo sapiens) 		PF00069
(Pkinase)
PF06479
(Ribonuc_2-5A) 		3 MET A 742
ASP A 756
ARG A 611
 None
 0.95A 5z6kA-4z7gA:
undetectable		 5z6kA-4z7gA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zg7 ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2

(Homo sapiens) 		PF01033
(Somatomedin_B)
PF01223
(Endonuclease_NS)
PF01663
(Phosphodiest) 		3 MET A 484
ASP A 474
ARG A 392
 None
None
CL  A 917 (-3.8A)
 1.22A 5z6kA-4zg7A:
1.3		 5z6kA-4zg7A:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aa5 NIFE-HYDROGENASE
SMALL SUBUNIT, HOFK
NIFE-HYDROGENASE
LARGE SUBUNIT, HOFG

(Cupriavidus
necator;
Cupriavidus
necator) 		PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
PF00374
(NiFeSe_Hases) 		3 MET A  77
ASP C  26
ARG C 568
 None
 1.17A 5z6kA-5aa5A:
undetectable		 5z6kA-5aa5A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnt ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Pseudomonas
aeruginosa) 		no annotation 3 MET C 142
ASP C 112
ARG C  20
 None
 1.14A 5z6kA-5bntC:
undetectable		 5z6kA-5bntC:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdi CHAPERONIN 60B1

(Chlamydomonas
reinhardtii) 		PF00118
(Cpn60_TCP1) 		3 MET A 194
ASP A 292
ARG A 351
 None
 1.11A 5z6kA-5cdiA:
undetectable		 5z6kA-5cdiA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d6a PREDICTED ATPASE OF
THE ABC CLASS

(Vibrio
vulnificus) 		PF09818
(ABC_ATPase) 		3 MET A 385
ASP A 390
ARG A 374
 None
 1.02A 5z6kA-5d6aA:
undetectable		 5z6kA-5d6aA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d6b FUMARATE HYDRATASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		3 MET A  77
ASP A  55
ARG A  51
 None
 1.15A 5z6kA-5d6bA:
undetectable		 5z6kA-5d6bA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e6k POLYKETIDE SYNTHASE
PKSL

(Bacillus
subtilis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 MET A 190
ASP A 252
ARG A 482
 None
 1.22A 5z6kA-5e6kA:
undetectable		 5z6kA-5e6kA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2g DIAMINOPIMELATE
EPIMERASE

(Corynebacterium
glutamicum) 		PF01678
(DAP_epimerase) 		3 MET A  33
ASP A  28
ARG A 110
 None
 1.16A 5z6kA-5h2gA:
undetectable		 5z6kA-5h2gA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j5t MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE KINASE
3

(Homo sapiens) 		PF00069
(Pkinase) 		3 MET A  90
ASP A 154
ARG A  21
 6G2  A 901 (-3.5A)
6G2  A 901 (-3.4A)
None
 1.14A 5z6kA-5j5tA:
undetectable		 5z6kA-5j5tA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpn COMPLEMENT C4-A
COMPLEMENT C4-A

(Homo sapiens;
Homo sapiens) 		PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF00207
(A2M)
PF01821
(ANATO)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		3 MET A 352
ASP B 768
ARG B 743
 None
 1.14A 5z6kA-5jpnA:
undetectable		 5z6kA-5jpnA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lad PUTATIVE GTP-BINDING
PROTEIN

(Thermotoga
maritima) 		PF01926
(MMR_HSR1) 		3 MET A 369
ASP A 337
ARG A  10
 None
 1.05A 5z6kA-5ladA:
undetectable		 5z6kA-5ladA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lfd ALLANTOIN RACEMASE

(Pseudomonas
fluorescens) 		no annotation 3 MET A 144
ASP A 152
ARG A 193
 None
 1.15A 5z6kA-5lfdA:
undetectable		 5z6kA-5lfdA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mch CELLOBIOHYDROLASE
CHBI

(Daphnia pulex) 		PF00840
(Glyco_hydro_7) 		3 MET A 363
ASP A 286
ARG A 334
 None
 1.17A 5z6kA-5mchA:
undetectable		 5z6kA-5mchA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN

(Bacillus
coagulans) 		no annotation 3 MET A 177
ASP A 251
ARG A  44
 None
 1.21A 5z6kA-5o7gA:
0.6		 5z6kA-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyp STRUCTURAL PROTEIN
VP2
STRUCTURAL PROTEIN
VP3

(Sacbrood virus;
Sacbrood virus) 		no annotation
no annotation 		3 MET B 156
ASP C 121
ARG C 239
 None
 1.06A 5z6kA-5oypB:
undetectable		 5z6kA-5oypB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3e BACILLAMIDE
SYNTHETASE
HETEROCYCLIZATION
DOMAIN

(Thermoactinomyces
vulgaris) 		PF00668
(Condensation) 		3 MET A1018
ASP A1133
ARG A1168
 None
 0.96A 5z6kA-5t3eA:
undetectable		 5z6kA-5t3eA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xm3 GLUCOSE
DEHYDROGENASE

(Methylophaga
aminisulfidivorans) 		no annotation 3 MET A 309
ASP A 334
ARG A 140
 None
MG  A 702 (-3.5A)
PQQ  A 701 (-3.3A)
 1.19A 5z6kA-5xm3A:
undetectable		 5z6kA-5xm3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xqo PCRGLX PROTEIN

(Penicillium
chrysogenum) 		no annotation 3 MET A 254
ASP A 665
ARG A 608
 None
 1.06A 5z6kA-5xqoA:
undetectable		 5z6kA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Vibrio harveyi) 		no annotation 3 MET A 489
ASP A 365
ARG A 436
 CBS  A 604 (-4.1A)
CBS  A 604 (-2.9A)
CBS  A 604 (-3.1A)
 1.19A 5z6kA-5yqwA:
undetectable		 5z6kA-5yqwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b5f NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE

(Yersinia
enterocolitica) 		no annotation 3 MET A  19
ASP A 282
ARG A  38
 None
 1.00A 5z6kA-6b5fA:
undetectable		 5z6kA-6b5fA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bac ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Neisseria
gonorrhoeae) 		no annotation 3 MET A 142
ASP A 112
ARG A  19
 None
 1.09A 5z6kA-6bacA:
undetectable		 5z6kA-6bacA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c6l V-TYPE PROTON ATPASE
SUBUNIT D
V-TYPE PROTON ATPASE
SUBUNIT C'

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		no annotation
no annotation 		3 MET D 128
ASP B 298
ARG B  18
 None
 1.22A 5z6kA-6c6lD:
undetectable		 5z6kA-6c6lD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c93 CYTOCHROME P450 4B1

(Oryctolagus
cuniculus) 		no annotation 3 MET A 308
ASP A 203
ARG A 257
 None
 0.80A 5z6kA-6c93A:
undetectable		 5z6kA-6c93A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MBH SUBUNIT
MONOVALENT CATION/H+
ANTIPORTER SUBUNIT D
MBH SUBUNIT

(Pyrococcus
furiosus;
Pyrococcus
furiosus;
Pyrococcus
furiosus) 		no annotation
no annotation
no annotation 		3 MET H 233
ASP I  88
ARG E   3
 None
 0.88A 5z6kA-6cfwH:
undetectable		 5z6kA-6cfwH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MONOVALENT CATION/H+
ANTIPORTER SUBUNIT C
MONOVALENT CATION/H+
ANTIPORTER SUBUNIT D
MBH SUBUNIT

(Pyrococcus
furiosus;
Pyrococcus
furiosus;
Pyrococcus
furiosus) 		no annotation
no annotation
no annotation 		3 MET H 298
ASP I  88
ARG G 113
 None
 1.18A 5z6kA-6cfwH:
undetectable		 5z6kA-6cfwH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eh1 STRUCTURAL PROTEIN
VP2
STRUCTURAL PROTEIN
VP3

(Sacbrood virus;
Sacbrood virus) 		no annotation
no annotation 		3 MET B 156
ASP C 121
ARG C 239
 None
 1.11A 5z6kA-6eh1B:
undetectable		 5z6kA-6eh1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6em0 2-HYDROXYBIPHENYL-3-
MONOOXYGENASE

(Pseudomonas
nitroreducens) 		no annotation 3 MET A 558
ASP A 489
ARG A 114
 None
 1.09A 5z6kA-6em0A:
undetectable		 5z6kA-6em0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en4 SPLICING FACTOR 3B
SUBUNIT 3

(Homo sapiens) 		no annotation 3 MET A 285
ASP A 279
ARG A 429
 None
 1.12A 5z6kA-6en4A:
undetectable		 5z6kA-6en4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8z ALPHA-1,2-MANNOSIDAS
E, PUTATIVE

(Bacteroides
thetaiotaomicron) 		no annotation 3 MET A  54
ASP A 324
ARG A 379
 None
 1.00A 5z6kA-6f8zA:
undetectable		 5z6kA-6f8zA:
undetectable