SIMILAR PATTERNS OF AMINO ACIDS FOR 5Z3J_A_NCAA302
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1abr | ABRIN-A (Abrusprecatorius) |
PF00161(RIP) | 6 | TYR A 74VAL A 75TYR A 113ILE A 159GLU A 164ARG A 167 | None | 0.36A | 5z3jA-1abrA:41.1 | 5z3jA-1abrA:99.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1aha | ALPHA-MOMORCHARIN (Momordicacharantia) |
PF00161(RIP) | 5 | TYR A 70TYR A 111ILE A 155GLU A 160ARG A 163 | ADE A 339 ( 3.8A)ADE A 339 ( 3.6A)ADE A 339 (-4.1A)ADE A 339 (-4.5A)ADE A 339 ( 2.9A) | 0.24A | 5z3jA-1ahaA:34.3 | 5z3jA-1ahaA:31.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1apa | POKEWEED ANTIVIRALPROTEIN (Phytolaccaamericana) |
PF00161(RIP) | 6 | TYR A 77VAL A 78TYR A 128ILE A 175GLU A 180ARG A 183 | None | 0.64A | 5z3jA-1apaA:32.1 | 5z3jA-1apaA:27.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1bry | BRYODIN I (Bryonia dioica) |
PF00161(RIP) | 5 | TYR Y 70TYR Y 111ILE Y 155GLU Y 160ARG Y 163 | None | 0.59A | 5z3jA-1bryY:34.6 | 5z3jA-1bryY:32.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ce7 | PROTEIN(RIBOSOME-INACTIVATING PROTEIN TYPE II) (Viscum album) |
PF00161(RIP) | 6 | TYR A 75VAL A 76TYR A 111ILE A 155GLU A 160ARG A 163 | None | 0.62A | 5z3jA-1ce7A:34.9 | 5z3jA-1ce7A:40.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1cf5 | PROTEIN(BETA-MOMORCHARIN) (Momordicacharantia) |
PF00161(RIP) | 5 | TYR A 70VAL A 71TYR A 109GLU A 158ARG A 161 | None | 0.61A | 5z3jA-1cf5A:34.6 | 5z3jA-1cf5A:37.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1cf5 | PROTEIN(BETA-MOMORCHARIN) (Momordicacharantia) |
PF00161(RIP) | 5 | VAL A 71TYR A 109ILE A 153GLU A 158ARG A 161 | None | 0.58A | 5z3jA-1cf5A:34.6 | 5z3jA-1cf5A:37.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dm0 | SHIGA TOXIN ASUBUNIT (Shigelladysenteriae) |
PF00161(RIP) | 4 | VAL A 78TYR A 114GLU A 167ARG A 170 | None | 0.50A | 5z3jA-1dm0A:23.1 | 5z3jA-1dm0A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1evj | GLUCOSE-FRUCTOSEOXIDOREDUCTASE (Zymomonasmobilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | VAL A 342TYR A 156GLU A 348ARG A 377 | None | 1.06A | 5z3jA-1evjA:undetectable | 5z3jA-1evjA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g01 | ENDOGLUCANASE (Bacillus sp.KSM-635) |
PF00150(Cellulase)PF03424(CBM_17_28) | 4 | VAL A 326TYR A 357ILE A 316GLU A 317 | None | 1.05A | 5z3jA-1g01A:undetectable | 5z3jA-1g01A:22.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ggp | PROTEIN (LECTIN 1 ACHAIN) (Trichosantheskirilowii) |
PF00161(RIP) | 5 | VAL A 75TYR A 113ILE A 159GLU A 164ARG A 167 | None | 0.76A | 5z3jA-1ggpA:32.2 | 5z3jA-1ggpA:48.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hfe | PROTEIN (FE-ONLYHYDROGENASE(E.C.1.18.99.1)(LARGER SUBUNIT))PROTEIN (FE-ONLYHYDROGENASE(E.C.1.18.99.1)(SMALLER SUBUNIT)) (Desulfovibriovulgaris;Desulfovibriovulgaris) |
PF02906(Fe_hyd_lg_C)PF13237(Fer4_10)PF02256(Fe_hyd_SSU) | 4 | VAL S 50ILE L 295GLU L 304ARG L 328 | None | 1.05A | 5z3jA-1hfeS:undetectable | 5z3jA-1hfeS:16.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hwn | EBULIN (Sambucus ebulus) |
PF00161(RIP) | 4 | TYR A 77TYR A 116GLU A 163ARG A 166 | None | 0.85A | 5z3jA-1hwnA:33.2 | 5z3jA-1hwnA:38.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hwn | EBULIN (Sambucus ebulus) |
PF00161(RIP) | 4 | TYR A 116ILE A 158GLU A 163ARG A 166 | None | 0.69A | 5z3jA-1hwnA:33.2 | 5z3jA-1hwnA:38.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j5x | GLUCOSAMINE-6-PHOSPHATE DEAMINASE (Thermotogamaritima) |
PF01380(SIS) | 4 | TYR A 52VAL A 46ILE A 73GLU A 77 | None | 1.01A | 5z3jA-1j5xA:undetectable | 5z3jA-1j5xA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lpc | DIANTHIN 30 (Dianthuscaryophyllus) |
PF00161(RIP) | 6 | TYR A 73VAL A 74TYR A 121ILE A 172GLU A 177ARG A 180 | CMP A 901 (-4.1A)CMP A 901 (-4.0A)CMP A 901 (-4.3A)CMP A 901 (-4.1A)CMP A 901 (-3.9A)CMP A 901 (-3.0A) | 0.56A | 5z3jA-1lpcA:28.1 | 5z3jA-1lpcA:25.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mp3 | GLUCOSE-1-PHOSPHATETHYMIDYLYLTRANSFERASE (Salmonellaenterica) |
PF00483(NTP_transferase) | 4 | VAL A 289TYR A 284GLU A 256ARG A 260 | NoneNoneTTP A 504 (-3.5A)None | 0.99A | 5z3jA-1mp3A:undetectable | 5z3jA-1mp3A:22.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1nio | B-LUFFIN (Luffaaegyptiaca) |
PF00161(RIP) | 5 | TYR A 71TYR A 111ILE A 155GLU A 160ARG A 163 | None | 0.39A | 5z3jA-1nioA:34.2 | 5z3jA-1nioA:33.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qcj | POKEWEED ANTIVIRALPROTEIN (Phytolaccaamericana) |
PF00161(RIP) | 6 | TYR A 72VAL A 73TYR A 123ILE A 171GLU A 176ARG A 179 | APT A 901 (-3.9A)APT A 901 (-3.4A)APT A 901 (-4.7A)APT A 901 (-3.7A)APT A 901 ( 3.6A)APT A 901 (-3.0A) | 0.63A | 5z3jA-1qcjA:32.4 | 5z3jA-1qcjA:27.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qi7 | PROTEIN(N-GLYCOSIDASE) (Saponariaofficinalis) |
PF00161(RIP) | 4 | TYR A 72VAL A 73GLU A 176ARG A 179 | None | 0.83A | 5z3jA-1qi7A:28.0 | 5z3jA-1qi7A:26.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qi7 | PROTEIN(N-GLYCOSIDASE) (Saponariaofficinalis) |
PF00161(RIP) | 5 | VAL A 73TYR A 120ILE A 171GLU A 176ARG A 179 | None | 0.91A | 5z3jA-1qi7A:28.0 | 5z3jA-1qi7A:26.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r4p | SHIGA-LIKE TOXINTYPE II A SUBUNIT (Escherichiacoli) |
PF00161(RIP) | 5 | TYR A 77VAL A 78TYR A 114GLU A 167ARG A 170 | FMT A3015 (-4.7A)FMT A3015 (-3.7A)FMT A3015 ( 4.1A)NoneNone | 0.69A | 5z3jA-1r4pA:24.3 | 5z3jA-1r4pA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t47 | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (Streptomycesavermitilis) |
PF00903(Glyoxalase) | 4 | TYR A 204VAL A 201TYR A 146ILE A 244 | None | 1.05A | 5z3jA-1t47A:undetectable | 5z3jA-1t47A:22.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tcs | TRICHOSANTHIN (Trichosantheskirilowii) |
PF00161(RIP) | 4 | TYR A 70ILE A 155GLU A 160ARG A 163 | NDP A 280 ( 4.7A)NDP A 280 (-3.9A)NDP A 280 ( 2.7A)NDP A 280 ( 2.6A) | 0.67A | 5z3jA-1tcsA:34.4 | 5z3jA-1tcsA:34.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tcs | TRICHOSANTHIN (Trichosantheskirilowii) |
PF00161(RIP) | 4 | TYR A 111ILE A 155GLU A 160ARG A 163 | NDP A 280 ( 3.7A)NDP A 280 (-3.9A)NDP A 280 ( 2.7A)NDP A 280 ( 2.6A) | 0.18A | 5z3jA-1tcsA:34.4 | 5z3jA-1tcsA:34.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v29 | NITRILE HYDRATASE BCHAIN (Bacillussmithii) |
PF02211(NHase_beta) | 4 | TYR B 197VAL B 199ILE B 148GLU B 146 | None | 0.79A | 5z3jA-1v29B:undetectable | 5z3jA-1v29B:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w1k | VANILLYL-ALCOHOLOXIDASE (Penicilliumsimplicissimum) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 4 | TYR A 187VAL A 168GLU A 410ARG A 398 | FAD A1561 (-4.7A)NoneNoneNone | 0.79A | 5z3jA-1w1kA:undetectable | 5z3jA-1w1kA:18.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1yf8 | BETA-GALACTOSIDE-SPECIFIC LECTIN 4 (Viscum album) |
PF00161(RIP) | 5 | TYR A 75VAL A 76ILE A 154GLU A 159ARG A 162 | P6C A1001 (-4.6A)NoneNoneP6C A1001 ( 4.4A)P6C A1001 (-2.6A) | 0.64A | 5z3jA-1yf8A:33.8 | 5z3jA-1yf8A:39.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zcz | BIFUNCTIONAL PURINEBIOSYNTHESIS PROTEINPURH (Thermotogamaritima) |
PF01808(AICARFT_IMPCHas)PF02142(MGS) | 4 | VAL A 330ILE A 432GLU A 433ARG A 436 | None | 0.98A | 5z3jA-1zczA:undetectable | 5z3jA-1zczA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cy1 | NUSA PROTEIN HOMOLOG (Aeropyrumpernix) |
PF07650(KH_2) | 4 | VAL A 131ILE A 30GLU A 11ARG A 28 | None | 1.06A | 5z3jA-2cy1A:undetectable | 5z3jA-2cy1A:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dpp | NITRILE HYDRATASEBETA SUBUNIT (Bacillus sp.RAPc8) |
PF02211(NHase_beta) | 4 | TYR B 197VAL B 199ILE B 148GLU B 146 | None | 0.93A | 5z3jA-2dppB:undetectable | 5z3jA-2dppB:23.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dvl | ACYL-COADEHYDROGENASE (Thermusthermophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | TYR A 345VAL A 342ILE A 253GLU A 252 | None | 1.02A | 5z3jA-2dvlA:undetectable | 5z3jA-2dvlA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g5x | RIBOSOME-INACTIVATING PROTEIN (Silenechalcedonica) |
PF00161(RIP) | 4 | TYR A 119ILE A 165GLU A 170ARG A 173 | None | 0.35A | 5z3jA-2g5xA:25.5 | 5z3jA-2g5xA:29.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h88 | SUCCINATEDEHYDROGENASEFLAVOPROTEIN SUBUNIT (Gallus gallus) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 4 | TYR A 287ILE A 306GLU A 307ARG A 312 | None | 0.64A | 5z3jA-2h88A:undetectable | 5z3jA-2h88A:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i3o | GAMMA-GLUTAMYLTRANSFERASE RELATEDPROTEIN (Thermoplasmaacidophilum) |
PF01019(G_glu_transpept) | 4 | VAL A 239ILE A 258GLU A 262ARG A 265 | None | 0.98A | 5z3jA-2i3oA:undetectable | 5z3jA-2i3oA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2igs | HYPOTHETICAL PROTEIN (Pseudomonasaeruginosa) |
PF11508(DUF3218) | 4 | VAL A 205TYR A 115ILE A 42GLU A 38 | None | 0.93A | 5z3jA-2igsA:undetectable | 5z3jA-2igsA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o36 | THIMETOLIGOPEPTIDASE (Homo sapiens) |
PF01432(Peptidase_M3) | 4 | VAL A 556ILE A 583GLU A 582ARG A 578 | None | 0.76A | 5z3jA-2o36A:undetectable | 5z3jA-2o36A:18.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oqa | LUFFACULIN 1 (Luffaacutangula) |
PF00161(RIP) | 5 | TYR A 70TYR A 110ILE A 154GLU A 159ARG A 162 | None | 0.48A | 5z3jA-2oqaA:34.5 | 5z3jA-2oqaA:32.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p1n | SKP1-LIKE PROTEIN 1A (Arabidopsisthaliana) |
PF01466(Skp1)PF03931(Skp1_POZ) | 4 | TYR A 58VAL A 55ILE A 110GLU A 25 | None | 1.06A | 5z3jA-2p1nA:undetectable | 5z3jA-2p1nA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pwz | MALATE DEHYDROGENASE (Escherichiacoli) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | VAL A 125TYR A 138GLU A 255ARG A 262 | None | 0.86A | 5z3jA-2pwzA:undetectable | 5z3jA-2pwzA:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q8w | POKEWEED ANTIVIRALPROTEIN (Phytolaccaacinosa) |
PF00161(RIP) | 6 | TYR A 72VAL A 73TYR A 122ILE A 170GLU A 175ARG A 178 | None | 0.65A | 5z3jA-2q8wA:32.0 | 5z3jA-2q8wA:28.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qes | RIBOSOME-INACTIVATING PROTEIN PD-L4 (Phytolaccadioica) |
PF00161(RIP) | 6 | TYR A 72VAL A 73TYR A 122ILE A 170GLU A 175ARG A 178 | ADE A 501 (-3.8A)ADE A 501 ( 3.9A)ADE A 501 (-3.7A)ADE A 501 (-4.0A)ADE A 501 ( 4.7A)ADE A 501 (-2.9A) | 0.24A | 5z3jA-2qesA:32.3 | 5z3jA-2qesA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qgm | SUCCINOGLYCANBIOSYNTHESIS PROTEIN (Bacillus cereus) |
PF05139(Erythro_esteras) | 4 | TYR A 322VAL A 323ILE A 314GLU A 317 | None | 1.04A | 5z3jA-2qgmA:undetectable | 5z3jA-2qgmA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vlc | TYPE 2RIBOSOME-INACTIVATING PROTEIN CINNAMOMINIII (Cinnamomumcamphora) |
PF00161(RIP)PF00652(Ricin_B_lectin) | 5 | TYR A 75VAL A 76ILE A 162GLU A 167ARG A 170 | None | 0.67A | 5z3jA-2vlcA:33.8 | 5z3jA-2vlcA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vlc | TYPE 2RIBOSOME-INACTIVATING PROTEIN CINNAMOMINIII (Cinnamomumcamphora) |
PF00161(RIP)PF00652(Ricin_B_lectin) | 5 | VAL A 76TYR A 115ILE A 162GLU A 167ARG A 170 | None | 0.29A | 5z3jA-2vlcA:33.8 | 5z3jA-2vlcA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w0c | PROTEIN 2 (Pseudoalteromonasvirus PM2) |
no annotation | 4 | TYR L 74ILE L 72GLU L 71ARG L 34 | None | 1.06A | 5z3jA-2w0cL:undetectable | 5z3jA-2w0cL:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w1q | HYALURONOGLUCOSAMINIDASE (Clostridiumperfringens) |
PF00754(F5_F8_type_C) | 4 | VAL A 910TYR A 899ILE A 911GLU A 913 | None | 0.92A | 5z3jA-2w1qA:undetectable | 5z3jA-2w1qA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wu5 | SUCCINATEDEHYDROGENASEFLAVOPROTEIN SUBUNIT (Escherichiacoli) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 4 | TYR A 276ILE A 295GLU A 296ARG A 301 | None | 0.60A | 5z3jA-2wu5A:undetectable | 5z3jA-2wu5A:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xwb | COMPLEMENT FACTOR B (Homo sapiens) |
PF00084(Sushi)PF00089(Trypsin)PF00092(VWA) | 4 | TYR F 278VAL F 280ILE F 217GLU F 218 | None | 0.96A | 5z3jA-2xwbF:undetectable | 5z3jA-2xwbF:15.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2zr1 | AGGLUTININ-1 CHAIN A (Abrusprecatorius) |
PF00161(RIP) | 6 | TYR A 73VAL A 74TYR A 112ILE A 158GLU A 163ARG A 166 | None | 0.47A | 5z3jA-2zr1A:40.2 | 5z3jA-2zr1A:64.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3bwh | CUCURMOSIN (Cucurbitamoschata) |
PF00161(RIP) | 5 | TYR A 70TYR A 109ILE A 153GLU A 158ARG A 161 | EDO A 253 ( 4.5A)EDO A 253 ( 4.1A)EDO A 253 ( 4.1A)EDO A 253 ( 4.6A)EDO A 253 (-2.9A) | 0.45A | 5z3jA-3bwhA:35.6 | 5z3jA-3bwhA:36.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c0k | UPF0064 PROTEIN YCCW (Escherichiacoli) |
PF10672(Methyltrans_SAM) | 4 | TYR A 204ILE A 185GLU A 187ARG A 209 | None | 0.97A | 5z3jA-3c0kA:undetectable | 5z3jA-3c0kA:20.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ctk | RRNA N-GLYCOSIDASE (Bougainvilleaspectabilis) |
PF00161(RIP) | 5 | TYR A 70VAL A 71ILE A 160GLU A 165ARG A 168 | None | 0.63A | 5z3jA-3ctkA:33.7 | 5z3jA-3ctkA:31.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ctk | RRNA N-GLYCOSIDASE (Bougainvilleaspectabilis) |
PF00161(RIP) | 5 | VAL A 71TYR A 114ILE A 160GLU A 165ARG A 168 | None | 0.18A | 5z3jA-3ctkA:33.7 | 5z3jA-3ctkA:31.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gmi | UPF0348 PROTEINMJ0951 (Methanocaldococcusjannaschii) |
PF05636(HIGH_NTase1)PF16581(HIGH_NTase1_ass) | 4 | VAL A 40ILE A 78GLU A 47ARG A 46 | None | 1.02A | 5z3jA-3gmiA:undetectable | 5z3jA-3gmiA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5k | RIBOSOME-INACTIVATING PROTEINPD-L1/PD-L2 (Phytolaccadioica) |
PF00161(RIP) | 6 | TYR A 72VAL A 73TYR A 122ILE A 170GLU A 175ARG A 178 | EDO A 264 ( 4.9A)NoneEDO A 264 (-3.5A)EDO A 264 (-4.0A)NoneNone | 0.46A | 5z3jA-3h5kA:31.9 | 5z3jA-3h5kA:28.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hiq | VACUOLAR SAPORIN (Saponariaofficinalis) |
PF00161(RIP) | 4 | VAL A 74TYR A 123GLU A 174ARG A 177 | None | 0.37A | 5z3jA-3hiqA:28.4 | 5z3jA-3hiqA:28.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hiw | VACUOLAR SAPORIN (Saponariaofficinalis) |
PF00161(RIP) | 5 | TYR A 73VAL A 74TYR A 123GLU A 174ARG A 177 | C2X A 260 (-3.4A)C2X A 260 (-3.9A)C2X A 260 (-3.7A)C2X A 260 (-3.0A)C2X A 260 (-2.9A) | 0.30A | 5z3jA-3hiwA:28.5 | 5z3jA-3hiwA:27.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iv3 | TAGATOSE1,6-DIPHOSPHATEALDOLASE 2 (Streptococcusmutans) |
PF01791(DeoC) | 4 | TYR A 145TYR A 91ILE A 149GLU A 152 | EDO A 336 (-4.1A)NoneNoneNone | 1.00A | 5z3jA-3iv3A:undetectable | 5z3jA-3iv3A:24.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jrk | TAGATOSE1,6-DIPHOSPHATEALDOLASE 2 (Streptococcuspyogenes) |
PF01791(DeoC) | 4 | TYR A 141TYR A 87ILE A 145GLU A 148 | None | 1.02A | 5z3jA-3jrkA:undetectable | 5z3jA-3jrkA:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kao | TAGATOSE1,6-DIPHOSPHATEALDOLASE (Staphylococcusaureus) |
PF01791(DeoC) | 4 | TYR A 145TYR A 91ILE A 149GLU A 152 | None | 1.00A | 5z3jA-3kaoA:undetectable | 5z3jA-3kaoA:20.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ku0 | RIBOSOME-INACTIVATING PROTEIN GELONIN (Suregadamultiflora) |
PF00161(RIP) | 5 | VAL A 75TYR A 113ILE A 161GLU A 166ARG A 169 | ADE A 800 (-3.9A)ADE A 800 (-3.5A)ADE A 800 (-4.0A)ADE A 800 ( 4.5A)ADE A 800 (-2.7A) | 0.26A | 5z3jA-3ku0A:34.2 | 5z3jA-3ku0A:34.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lmd | GERANYLGERANYLPYROPHOSPHATESYNTHASE (Corynebacteriumglutamicum) |
PF00348(polyprenyl_synt) | 4 | TYR A 318VAL A 315TYR A 190ILE A 236 | None | 0.99A | 5z3jA-3lmdA:undetectable | 5z3jA-3lmdA:21.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mvg | RIBOSOMEINACTIVATING TYPE 1PROTEIN (Iris xhollandica) |
PF00161(RIP) | 5 | VAL A 73TYR A 108ILE A 156GLU A 161ARG A 164 | NoneGOL A 281 (-4.4A)NoneNoneGOL A 284 (-3.1A) | 0.38A | 5z3jA-3mvgA:32.7 | 5z3jA-3mvgA:31.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3myo | TAGATOSE1,6-DIPHOSPHATEALDOLASE 1 (Streptococcuspyogenes) |
PF01791(DeoC) | 4 | TYR A 144TYR A 90ILE A 148GLU A 151 | None | 1.02A | 5z3jA-3myoA:undetectable | 5z3jA-3myoA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o04 | BETA-KETO-ACYLCARRIER PROTEINSYNTHASE II (Listeriamonocytogenes) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | VAL A 86ILE A 239GLU A 241ARG A 249 | None | 0.99A | 5z3jA-3o04A:undetectable | 5z3jA-3o04A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oug | ASPARTATE1-DECARBOXYLASE (Francisellatularensis) |
PF02261(Asp_decarbox) | 4 | TYR A 58VAL A 59TYR A 22ILE A 60 | None | 1.04A | 5z3jA-3ougA:undetectable | 5z3jA-3ougA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uhj | PROBABLE GLYCEROLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00465(Fe-ADH) | 4 | TYR A 47ILE A 35GLU A 40ARG A 37 | None | 0.96A | 5z3jA-3uhjA:undetectable | 5z3jA-3uhjA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vpp | C-TYPE LECTIN DOMAINFAMILY 9 MEMBER A (Homo sapiens) |
PF00059(Lectin_C) | 4 | VAL A 214TYR A 125ILE A 160GLU A 156 | NoneNoneNone CA A 301 (-2.4A) | 1.04A | 5z3jA-3vppA:undetectable | 5z3jA-3vppA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vrb | FLAVOPROTEIN SUBUNITOF COMPLEX II (Ascaris suum) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 4 | TYR A 310ILE A 329GLU A 330ARG A 335 | None | 0.70A | 5z3jA-3vrbA:undetectable | 5z3jA-3vrbA:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a1g | MITOTIC CHECKPOINTSERINE/THREONINE-PROTEIN KINASE BUB1 (Homo sapiens) |
PF08311(Mad3_BUB1_I) | 4 | VAL A 34TYR A 71ILE A 31GLU A 28 | None | 1.07A | 5z3jA-4a1gA:undetectable | 5z3jA-4a1gA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gf8 | PEPTIDE ABCTRANSPORTER,PERIPLASMICPEPTIDE-BINDINGPROTEIN (Vibrio cholerae) |
PF00496(SBP_bac_5) | 4 | VAL A 522TYR A 184GLU A 35ARG A 51 | None | 1.01A | 5z3jA-4gf8A:undetectable | 5z3jA-4gf8A:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h7l | UNCHARACTERIZEDPROTEIN (Planctopiruslimnophila) |
no annotation | 4 | VAL A 99TYR A 67ILE A 95GLU A 65 | NoneNoneNone CU A 201 (-2.4A) | 0.95A | 5z3jA-4h7lA:undetectable | 5z3jA-4h7lA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4imv | RICIN (Ricinuscommunis) |
PF00161(RIP) | 4 | VAL A 81TYR A 123ILE A 172GLU A 177 | None | 0.60A | 5z3jA-4imvA:18.7 | 5z3jA-4imvA:28.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4jkx | BETA-GALACTOSIDE-SPECIFIC LECTIN 1 ACHAIN (Viscum album) |
PF00161(RIP) | 5 | TYR A 76VAL A 77ILE A 160GLU A 165ARG A 168 | H35 A 305 (-4.2A)NoneH35 A 305 ( 4.5A)H35 A 305 (-3.5A)H35 A 305 (-3.3A) | 0.54A | 5z3jA-4jkxA:35.4 | 5z3jA-4jkxA:40.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jwo | PHOSPHATE BINDINGPROTEIN (Planctopiruslimnophila) |
PF12727(PBP_like) | 4 | VAL A 109ILE A 60GLU A 296ARG A 294 | None | 1.07A | 5z3jA-4jwoA:undetectable | 5z3jA-4jwoA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oc9 | PUTATIVEO-ACETYLHOMOSERINE(THIOL)-LYASE (Campylobacterjejuni) |
PF01053(Cys_Met_Meta_PP) | 4 | VAL A 196TYR A 332ILE A 163GLU A 164 | None | 0.98A | 5z3jA-4oc9A:undetectable | 5z3jA-4oc9A:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pcs | ALPHA-L-FUCOSIDASE (Bacteroidesthetaiotaomicron) |
PF01120(Alpha_L_fucos) | 4 | TYR A 156VAL A 151ILE A 160GLU A 163 | None | 0.94A | 5z3jA-4pcsA:undetectable | 5z3jA-4pcsA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q1j | POLYKETIDEBIOSYNTHESISENOYL-COA ISOMERASEPKSI (Bacillussubtilis) |
PF00378(ECH_1) | 4 | VAL A 146TYR A 165ILE A 158GLU A 157 | NoneEDO A 303 (-4.8A)NoneEDO A 303 ( 4.6A) | 0.93A | 5z3jA-4q1jA:undetectable | 5z3jA-4q1jA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q66 | PROTEIN BCH1 (Saccharomycescerevisiae) |
no annotation | 4 | VAL K 189TYR K 146ILE K 192GLU K 195 | None | 1.05A | 5z3jA-4q66K:undetectable | 5z3jA-4q66K:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rxe | FARNESYLPYROPHOSPHATESYNTHASE (Trypanosomabrucei) |
PF00348(polyprenyl_synt) | 4 | VAL A 355ILE A 341GLU A 342ARG A 345 | None | 0.97A | 5z3jA-4rxeA:undetectable | 5z3jA-4rxeA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbq | QDE-2-INTERACTINGPROTEIN (Neurosporacrassa) |
no annotation | 4 | VAL A 441TYR A 460ILE A 426GLU A 427 | None | 1.03A | 5z3jA-4wbqA:undetectable | 5z3jA-4wbqA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzo | PUTATIVE ACYL-COAACYLTRANSFERASE (Sulfurisphaeratokodaii) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 4 | VAL A 296TYR A 142ILE A 278GLU A 282 | None | 0.97A | 5z3jA-4yzoA:undetectable | 5z3jA-4yzoA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zk7 | DIVALENT-CATIONTOLERANCE PROTEINCUTA (Thermusthermophilus) |
PF03091(CutA1) | 4 | TYR M 77VAL M 79TYR M 41GLU M 43 | None | 0.94A | 5z3jA-4zk7M:undetectable | 5z3jA-4zk7M:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zq0 | 14-3-3 PROTEIN (Giardiaintestinalis) |
PF00244(14-3-3) | 4 | TYR A 127VAL A 124ILE A 163GLU A 162 | None | 0.74A | 5z3jA-4zq0A:undetectable | 5z3jA-4zq0A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aa5 | NIFE-HYDROGENASELARGE SUBUNIT, HOFG (Cupriavidusnecator) |
PF00374(NiFeSe_Hases) | 4 | TYR C 253ILE C 446GLU C 447ARG C 450 | None | 0.98A | 5z3jA-5aa5C:undetectable | 5z3jA-5aa5C:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bob | TRANSLATIONINITIATION FACTOR 2(IF-2 GTPASE) (Streptococcussuis) |
no annotation | 4 | TYR A 295VAL A 211TYR A 237ILE A 218 | None | 1.07A | 5z3jA-5bobA:undetectable | 5z3jA-5bobA:23.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ddz | RICIN (Ricinuscommunis) |
PF00161(RIP) | 5 | VAL A 81TYR A 123ILE A 172GLU A 177ARG A 180 | None | 0.38A | 5z3jA-5ddzA:35.6 | 5z3jA-5ddzA:41.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fu6 | CCR4-NOTTRANSCRIPTIONCOMPLEX SUBUNIT 3 (Homo sapiens) |
PF04153(NOT2_3_5) | 4 | TYR C 744ILE C 715GLU C 720ARG C 708 | None | 0.96A | 5z3jA-5fu6C:undetectable | 5z3jA-5fu6C:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hjl | TAGATOSE1,6-DIPHOSPHATEALDOLASE (Streptococcusporcinus) |
PF01791(DeoC) | 4 | TYR A 144TYR A 90ILE A 148GLU A 151 | None | 1.00A | 5z3jA-5hjlA:undetectable | 5z3jA-5hjlA:24.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irc | RHOGTPASE-ACTIVATINGPROTEIN 35 (Rattusnorvegicus) |
PF00620(RhoGAP) | 4 | VAL A1375ILE A1269GLU A1273ARG A1381 | None | 0.82A | 5z3jA-5ircA:undetectable | 5z3jA-5ircA:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n6n | PROTEIN BMH1 (Saccharomycescerevisiae) |
no annotation | 4 | TYR A 124VAL A 121ILE A 160GLU A 159 | None | 0.85A | 5z3jA-5n6nA:undetectable | 5z3jA-5n6nA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ue8 | PROTEIN UNC-13HOMOLOG A (Rattusnorvegicus) |
PF00130(C1_1)PF00168(C2)PF06292(DUF1041)PF10540(Membr_traf_MHD) | 4 | VAL A1395ILE A1325GLU A1326ARG A1401 | None | 0.85A | 5z3jA-5ue8A:undetectable | 5z3jA-5ue8A:15.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vj1 | MDCA (Pseudomonasaeruginosa) |
PF16957(Mal_decarbox_Al) | 4 | VAL A 306TYR A 321ILE A 301GLU A 302 | None | 0.99A | 5z3jA-5vj1A:undetectable | 5z3jA-5vj1A:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yqw | PEPTIDE ABCTRANSPORTER,PERIPLASMICPEPTIDE-BINDINGPROTEIN (Vibrio harveyi) |
no annotation | 4 | VAL A 523TYR A 185GLU A 36ARG A 52 | None | 1.03A | 5z3jA-5yqwA:undetectable | 5z3jA-5yqwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6aoo | MALATE DEHYDROGENASE (Haemophilusinfluenzae) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | VAL A 125TYR A 138GLU A 254ARG A 261 | None | 0.90A | 5z3jA-6aooA:undetectable | 5z3jA-6aooA:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bev | THIOSULFATESULFURTRANSFERASE/RHODANESE-LIKEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
no annotation | 4 | VAL A 26TYR A 63ILE A 43GLU A 47 | None | 1.07A | 5z3jA-6bevA:undetectable | 5z3jA-6bevA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bsz | METABOTROPICGLUTAMATE RECEPTOR 8 (Homo sapiens) |
no annotation | 4 | TYR A 319VAL A 318ILE A 315GLU A 70 | None | 0.97A | 5z3jA-6bszA:undetectable | 5z3jA-6bszA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d6t | HUMAN GABA-ARECEPTOR SUBUNITGAMMA-2 (Homo sapiens) |
no annotation | 4 | TYR E 220VAL E 221ILE E 179GLU E 178 | None | 1.07A | 5z3jA-6d6tE:undetectable | 5z3jA-6d6tE:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dw1 | - (-) |
no annotation | 4 | TYR D 220VAL D 221ILE D 179GLU D 178 | None | 0.94A | 5z3jA-6dw1D:undetectable | 5z3jA-6dw1D:undetectable |