SIMILAR PATTERNS OF AMINO ACIDS FOR 5Z3J_A_NCAA302

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1abr ABRIN-A

(Abrus
precatorius)
PF00161
(RIP)
6 TYR A  74
VAL A  75
TYR A 113
ILE A 159
GLU A 164
ARG A 167
None
0.36A 5z3jA-1abrA:
41.1
5z3jA-1abrA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1aha ALPHA-MOMORCHARIN

(Momordica
charantia)
PF00161
(RIP)
5 TYR A  70
TYR A 111
ILE A 155
GLU A 160
ARG A 163
ADE  A 339 ( 3.8A)
ADE  A 339 ( 3.6A)
ADE  A 339 (-4.1A)
ADE  A 339 (-4.5A)
ADE  A 339 ( 2.9A)
0.24A 5z3jA-1ahaA:
34.3
5z3jA-1ahaA:
31.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1apa POKEWEED ANTIVIRAL
PROTEIN


(Phytolacca
americana)
PF00161
(RIP)
6 TYR A  77
VAL A  78
TYR A 128
ILE A 175
GLU A 180
ARG A 183
None
0.64A 5z3jA-1apaA:
32.1
5z3jA-1apaA:
27.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bry BRYODIN I

(Bryonia dioica)
PF00161
(RIP)
5 TYR Y  70
TYR Y 111
ILE Y 155
GLU Y 160
ARG Y 163
None
0.59A 5z3jA-1bryY:
34.6
5z3jA-1bryY:
32.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ce7 PROTEIN
(RIBOSOME-INACTIVATI
NG PROTEIN TYPE II)


(Viscum album)
PF00161
(RIP)
6 TYR A  75
VAL A  76
TYR A 111
ILE A 155
GLU A 160
ARG A 163
None
0.62A 5z3jA-1ce7A:
34.9
5z3jA-1ce7A:
40.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1cf5 PROTEIN
(BETA-MOMORCHARIN)


(Momordica
charantia)
PF00161
(RIP)
5 TYR A  70
VAL A  71
TYR A 109
GLU A 158
ARG A 161
None
0.61A 5z3jA-1cf5A:
34.6
5z3jA-1cf5A:
37.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1cf5 PROTEIN
(BETA-MOMORCHARIN)


(Momordica
charantia)
PF00161
(RIP)
5 VAL A  71
TYR A 109
ILE A 153
GLU A 158
ARG A 161
None
0.58A 5z3jA-1cf5A:
34.6
5z3jA-1cf5A:
37.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dm0 SHIGA TOXIN A
SUBUNIT


(Shigella
dysenteriae)
PF00161
(RIP)
4 VAL A  78
TYR A 114
GLU A 167
ARG A 170
None
0.50A 5z3jA-1dm0A:
23.1
5z3jA-1dm0A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1evj GLUCOSE-FRUCTOSE
OXIDOREDUCTASE


(Zymomonas
mobilis)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
4 VAL A 342
TYR A 156
GLU A 348
ARG A 377
None
1.06A 5z3jA-1evjA:
undetectable
5z3jA-1evjA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g01 ENDOGLUCANASE

(Bacillus sp.
KSM-635)
PF00150
(Cellulase)
PF03424
(CBM_17_28)
4 VAL A 326
TYR A 357
ILE A 316
GLU A 317
None
1.05A 5z3jA-1g01A:
undetectable
5z3jA-1g01A:
22.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ggp PROTEIN (LECTIN 1 A
CHAIN)


(Trichosanthes
kirilowii)
PF00161
(RIP)
5 VAL A  75
TYR A 113
ILE A 159
GLU A 164
ARG A 167
None
0.76A 5z3jA-1ggpA:
32.2
5z3jA-1ggpA:
48.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hfe PROTEIN (FE-ONLY
HYDROGENASE
(E.C.1.18.99.1)
(LARGER SUBUNIT))
PROTEIN (FE-ONLY
HYDROGENASE
(E.C.1.18.99.1)
(SMALLER SUBUNIT))


(Desulfovibrio
vulgaris;
Desulfovibrio
vulgaris)
PF02906
(Fe_hyd_lg_C)
PF13237
(Fer4_10)
PF02256
(Fe_hyd_SSU)
4 VAL S  50
ILE L 295
GLU L 304
ARG L 328
None
1.05A 5z3jA-1hfeS:
undetectable
5z3jA-1hfeS:
16.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hwn EBULIN

(Sambucus ebulus)
PF00161
(RIP)
4 TYR A  77
TYR A 116
GLU A 163
ARG A 166
None
0.85A 5z3jA-1hwnA:
33.2
5z3jA-1hwnA:
38.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hwn EBULIN

(Sambucus ebulus)
PF00161
(RIP)
4 TYR A 116
ILE A 158
GLU A 163
ARG A 166
None
0.69A 5z3jA-1hwnA:
33.2
5z3jA-1hwnA:
38.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5x GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE


(Thermotoga
maritima)
PF01380
(SIS)
4 TYR A  52
VAL A  46
ILE A  73
GLU A  77
None
1.01A 5z3jA-1j5xA:
undetectable
5z3jA-1j5xA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lpc DIANTHIN 30

(Dianthus
caryophyllus)
PF00161
(RIP)
6 TYR A  73
VAL A  74
TYR A 121
ILE A 172
GLU A 177
ARG A 180
CMP  A 901 (-4.1A)
CMP  A 901 (-4.0A)
CMP  A 901 (-4.3A)
CMP  A 901 (-4.1A)
CMP  A 901 (-3.9A)
CMP  A 901 (-3.0A)
0.56A 5z3jA-1lpcA:
28.1
5z3jA-1lpcA:
25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E


(Salmonella
enterica)
PF00483
(NTP_transferase)
4 VAL A 289
TYR A 284
GLU A 256
ARG A 260
None
None
TTP  A 504 (-3.5A)
None
0.99A 5z3jA-1mp3A:
undetectable
5z3jA-1mp3A:
22.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1nio B-LUFFIN

(Luffa
aegyptiaca)
PF00161
(RIP)
5 TYR A  71
TYR A 111
ILE A 155
GLU A 160
ARG A 163
None
0.39A 5z3jA-1nioA:
34.2
5z3jA-1nioA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qcj POKEWEED ANTIVIRAL
PROTEIN


(Phytolacca
americana)
PF00161
(RIP)
6 TYR A  72
VAL A  73
TYR A 123
ILE A 171
GLU A 176
ARG A 179
APT  A 901 (-3.9A)
APT  A 901 (-3.4A)
APT  A 901 (-4.7A)
APT  A 901 (-3.7A)
APT  A 901 ( 3.6A)
APT  A 901 (-3.0A)
0.63A 5z3jA-1qcjA:
32.4
5z3jA-1qcjA:
27.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qi7 PROTEIN
(N-GLYCOSIDASE)


(Saponaria
officinalis)
PF00161
(RIP)
4 TYR A  72
VAL A  73
GLU A 176
ARG A 179
None
0.83A 5z3jA-1qi7A:
28.0
5z3jA-1qi7A:
26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qi7 PROTEIN
(N-GLYCOSIDASE)


(Saponaria
officinalis)
PF00161
(RIP)
5 VAL A  73
TYR A 120
ILE A 171
GLU A 176
ARG A 179
None
0.91A 5z3jA-1qi7A:
28.0
5z3jA-1qi7A:
26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r4p SHIGA-LIKE TOXIN
TYPE II A SUBUNIT


(Escherichia
coli)
PF00161
(RIP)
5 TYR A  77
VAL A  78
TYR A 114
GLU A 167
ARG A 170
FMT  A3015 (-4.7A)
FMT  A3015 (-3.7A)
FMT  A3015 ( 4.1A)
None
None
0.69A 5z3jA-1r4pA:
24.3
5z3jA-1r4pA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t47 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE


(Streptomyces
avermitilis)
PF00903
(Glyoxalase)
4 TYR A 204
VAL A 201
TYR A 146
ILE A 244
None
1.05A 5z3jA-1t47A:
undetectable
5z3jA-1t47A:
22.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tcs TRICHOSANTHIN

(Trichosanthes
kirilowii)
PF00161
(RIP)
4 TYR A  70
ILE A 155
GLU A 160
ARG A 163
NDP  A 280 ( 4.7A)
NDP  A 280 (-3.9A)
NDP  A 280 ( 2.7A)
NDP  A 280 ( 2.6A)
0.67A 5z3jA-1tcsA:
34.4
5z3jA-1tcsA:
34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tcs TRICHOSANTHIN

(Trichosanthes
kirilowii)
PF00161
(RIP)
4 TYR A 111
ILE A 155
GLU A 160
ARG A 163
NDP  A 280 ( 3.7A)
NDP  A 280 (-3.9A)
NDP  A 280 ( 2.7A)
NDP  A 280 ( 2.6A)
0.18A 5z3jA-1tcsA:
34.4
5z3jA-1tcsA:
34.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v29 NITRILE HYDRATASE B
CHAIN


(Bacillus
smithii)
PF02211
(NHase_beta)
4 TYR B 197
VAL B 199
ILE B 148
GLU B 146
None
0.79A 5z3jA-1v29B:
undetectable
5z3jA-1v29B:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w1k VANILLYL-ALCOHOL
OXIDASE


(Penicillium
simplicissimum)
PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C)
4 TYR A 187
VAL A 168
GLU A 410
ARG A 398
FAD  A1561 (-4.7A)
None
None
None
0.79A 5z3jA-1w1kA:
undetectable
5z3jA-1w1kA:
18.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4


(Viscum album)
PF00161
(RIP)
5 TYR A  75
VAL A  76
ILE A 154
GLU A 159
ARG A 162
P6C  A1001 (-4.6A)
None
None
P6C  A1001 ( 4.4A)
P6C  A1001 (-2.6A)
0.64A 5z3jA-1yf8A:
33.8
5z3jA-1yf8A:
39.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zcz BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH


(Thermotoga
maritima)
PF01808
(AICARFT_IMPCHas)
PF02142
(MGS)
4 VAL A 330
ILE A 432
GLU A 433
ARG A 436
None
0.98A 5z3jA-1zczA:
undetectable
5z3jA-1zczA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cy1 NUSA PROTEIN HOMOLOG

(Aeropyrum
pernix)
PF07650
(KH_2)
4 VAL A 131
ILE A  30
GLU A  11
ARG A  28
None
1.06A 5z3jA-2cy1A:
undetectable
5z3jA-2cy1A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpp NITRILE HYDRATASE
BETA SUBUNIT


(Bacillus sp.
RAPc8)
PF02211
(NHase_beta)
4 TYR B 197
VAL B 199
ILE B 148
GLU B 146
None
0.93A 5z3jA-2dppB:
undetectable
5z3jA-2dppB:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dvl ACYL-COA
DEHYDROGENASE


(Thermus
thermophilus)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
4 TYR A 345
VAL A 342
ILE A 253
GLU A 252
None
1.02A 5z3jA-2dvlA:
undetectable
5z3jA-2dvlA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g5x RIBOSOME-INACTIVATIN
G PROTEIN


(Silene
chalcedonica)
PF00161
(RIP)
4 TYR A 119
ILE A 165
GLU A 170
ARG A 173
None
0.35A 5z3jA-2g5xA:
25.5
5z3jA-2g5xA:
29.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h88 SUCCINATE
DEHYDROGENASE
FLAVOPROTEIN SUBUNIT


(Gallus gallus)
PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C)
4 TYR A 287
ILE A 306
GLU A 307
ARG A 312
None
0.64A 5z3jA-2h88A:
undetectable
5z3jA-2h88A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i3o GAMMA-GLUTAMYLTRANSF
ERASE RELATED
PROTEIN


(Thermoplasma
acidophilum)
PF01019
(G_glu_transpept)
4 VAL A 239
ILE A 258
GLU A 262
ARG A 265
None
0.98A 5z3jA-2i3oA:
undetectable
5z3jA-2i3oA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2igs HYPOTHETICAL PROTEIN

(Pseudomonas
aeruginosa)
PF11508
(DUF3218)
4 VAL A 205
TYR A 115
ILE A  42
GLU A  38
None
0.93A 5z3jA-2igsA:
undetectable
5z3jA-2igsA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o36 THIMET
OLIGOPEPTIDASE


(Homo sapiens)
PF01432
(Peptidase_M3)
4 VAL A 556
ILE A 583
GLU A 582
ARG A 578
None
0.76A 5z3jA-2o36A:
undetectable
5z3jA-2o36A:
18.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2oqa LUFFACULIN 1

(Luffa
acutangula)
PF00161
(RIP)
5 TYR A  70
TYR A 110
ILE A 154
GLU A 159
ARG A 162
None
0.48A 5z3jA-2oqaA:
34.5
5z3jA-2oqaA:
32.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1n SKP1-LIKE PROTEIN 1A

(Arabidopsis
thaliana)
PF01466
(Skp1)
PF03931
(Skp1_POZ)
4 TYR A  58
VAL A  55
ILE A 110
GLU A  25
None
1.06A 5z3jA-2p1nA:
undetectable
5z3jA-2p1nA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pwz MALATE DEHYDROGENASE

(Escherichia
coli)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 VAL A 125
TYR A 138
GLU A 255
ARG A 262
None
0.86A 5z3jA-2pwzA:
undetectable
5z3jA-2pwzA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q8w POKEWEED ANTIVIRAL
PROTEIN


(Phytolacca
acinosa)
PF00161
(RIP)
6 TYR A  72
VAL A  73
TYR A 122
ILE A 170
GLU A 175
ARG A 178
None
0.65A 5z3jA-2q8wA:
32.0
5z3jA-2q8wA:
28.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qes RIBOSOME-INACTIVATIN
G PROTEIN PD-L4


(Phytolacca
dioica)
PF00161
(RIP)
6 TYR A  72
VAL A  73
TYR A 122
ILE A 170
GLU A 175
ARG A 178
ADE  A 501 (-3.8A)
ADE  A 501 ( 3.9A)
ADE  A 501 (-3.7A)
ADE  A 501 (-4.0A)
ADE  A 501 ( 4.7A)
ADE  A 501 (-2.9A)
0.24A 5z3jA-2qesA:
32.3
5z3jA-2qesA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgm SUCCINOGLYCAN
BIOSYNTHESIS PROTEIN


(Bacillus cereus)
PF05139
(Erythro_esteras)
4 TYR A 322
VAL A 323
ILE A 314
GLU A 317
None
1.04A 5z3jA-2qgmA:
undetectable
5z3jA-2qgmA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III


(Cinnamomum
camphora)
PF00161
(RIP)
PF00652
(Ricin_B_lectin)
5 TYR A  75
VAL A  76
ILE A 162
GLU A 167
ARG A 170
None
0.67A 5z3jA-2vlcA:
33.8
5z3jA-2vlcA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III


(Cinnamomum
camphora)
PF00161
(RIP)
PF00652
(Ricin_B_lectin)
5 VAL A  76
TYR A 115
ILE A 162
GLU A 167
ARG A 170
None
0.29A 5z3jA-2vlcA:
33.8
5z3jA-2vlcA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w0c PROTEIN 2

(Pseudoalteromonas
virus PM2)
no annotation 4 TYR L  74
ILE L  72
GLU L  71
ARG L  34
None
1.06A 5z3jA-2w0cL:
undetectable
5z3jA-2w0cL:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w1q HYALURONOGLUCOSAMINI
DASE


(Clostridium
perfringens)
PF00754
(F5_F8_type_C)
4 VAL A 910
TYR A 899
ILE A 911
GLU A 913
None
0.92A 5z3jA-2w1qA:
undetectable
5z3jA-2w1qA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu5 SUCCINATE
DEHYDROGENASE
FLAVOPROTEIN SUBUNIT


(Escherichia
coli)
PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C)
4 TYR A 276
ILE A 295
GLU A 296
ARG A 301
None
0.60A 5z3jA-2wu5A:
undetectable
5z3jA-2wu5A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwb COMPLEMENT FACTOR B

(Homo sapiens)
PF00084
(Sushi)
PF00089
(Trypsin)
PF00092
(VWA)
4 TYR F 278
VAL F 280
ILE F 217
GLU F 218
None
0.96A 5z3jA-2xwbF:
undetectable
5z3jA-2xwbF:
15.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zr1 AGGLUTININ-1 CHAIN A

(Abrus
precatorius)
PF00161
(RIP)
6 TYR A  73
VAL A  74
TYR A 112
ILE A 158
GLU A 163
ARG A 166
None
0.47A 5z3jA-2zr1A:
40.2
5z3jA-2zr1A:
64.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3bwh CUCURMOSIN

(Cucurbita
moschata)
PF00161
(RIP)
5 TYR A  70
TYR A 109
ILE A 153
GLU A 158
ARG A 161
EDO  A 253 ( 4.5A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.6A)
EDO  A 253 (-2.9A)
0.45A 5z3jA-3bwhA:
35.6
5z3jA-3bwhA:
36.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c0k UPF0064 PROTEIN YCCW

(Escherichia
coli)
PF10672
(Methyltrans_SAM)
4 TYR A 204
ILE A 185
GLU A 187
ARG A 209
None
0.97A 5z3jA-3c0kA:
undetectable
5z3jA-3c0kA:
20.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ctk RRNA N-GLYCOSIDASE

(Bougainvillea
spectabilis)
PF00161
(RIP)
5 TYR A  70
VAL A  71
ILE A 160
GLU A 165
ARG A 168
None
0.63A 5z3jA-3ctkA:
33.7
5z3jA-3ctkA:
31.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ctk RRNA N-GLYCOSIDASE

(Bougainvillea
spectabilis)
PF00161
(RIP)
5 VAL A  71
TYR A 114
ILE A 160
GLU A 165
ARG A 168
None
0.18A 5z3jA-3ctkA:
33.7
5z3jA-3ctkA:
31.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gmi UPF0348 PROTEIN
MJ0951


(Methanocaldococcus
jannaschii)
PF05636
(HIGH_NTase1)
PF16581
(HIGH_NTase1_ass)
4 VAL A  40
ILE A  78
GLU A  47
ARG A  46
None
1.02A 5z3jA-3gmiA:
undetectable
5z3jA-3gmiA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5k RIBOSOME-INACTIVATIN
G PROTEIN
PD-L1/PD-L2


(Phytolacca
dioica)
PF00161
(RIP)
6 TYR A  72
VAL A  73
TYR A 122
ILE A 170
GLU A 175
ARG A 178
EDO  A 264 ( 4.9A)
None
EDO  A 264 (-3.5A)
EDO  A 264 (-4.0A)
None
None
0.46A 5z3jA-3h5kA:
31.9
5z3jA-3h5kA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hiq VACUOLAR SAPORIN

(Saponaria
officinalis)
PF00161
(RIP)
4 VAL A  74
TYR A 123
GLU A 174
ARG A 177
None
0.37A 5z3jA-3hiqA:
28.4
5z3jA-3hiqA:
28.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hiw VACUOLAR SAPORIN

(Saponaria
officinalis)
PF00161
(RIP)
5 TYR A  73
VAL A  74
TYR A 123
GLU A 174
ARG A 177
C2X  A 260 (-3.4A)
C2X  A 260 (-3.9A)
C2X  A 260 (-3.7A)
C2X  A 260 (-3.0A)
C2X  A 260 (-2.9A)
0.30A 5z3jA-3hiwA:
28.5
5z3jA-3hiwA:
27.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iv3 TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 2


(Streptococcus
mutans)
PF01791
(DeoC)
4 TYR A 145
TYR A  91
ILE A 149
GLU A 152
EDO  A 336 (-4.1A)
None
None
None
1.00A 5z3jA-3iv3A:
undetectable
5z3jA-3iv3A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jrk TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 2


(Streptococcus
pyogenes)
PF01791
(DeoC)
4 TYR A 141
TYR A  87
ILE A 145
GLU A 148
None
1.02A 5z3jA-3jrkA:
undetectable
5z3jA-3jrkA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kao TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE


(Staphylococcus
aureus)
PF01791
(DeoC)
4 TYR A 145
TYR A  91
ILE A 149
GLU A 152
None
1.00A 5z3jA-3kaoA:
undetectable
5z3jA-3kaoA:
20.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN


(Suregada
multiflora)
PF00161
(RIP)
5 VAL A  75
TYR A 113
ILE A 161
GLU A 166
ARG A 169
ADE  A 800 (-3.9A)
ADE  A 800 (-3.5A)
ADE  A 800 (-4.0A)
ADE  A 800 ( 4.5A)
ADE  A 800 (-2.7A)
0.26A 5z3jA-3ku0A:
34.2
5z3jA-3ku0A:
34.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lmd GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE


(Corynebacterium
glutamicum)
PF00348
(polyprenyl_synt)
4 TYR A 318
VAL A 315
TYR A 190
ILE A 236
None
0.99A 5z3jA-3lmdA:
undetectable
5z3jA-3lmdA:
21.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN


(Iris x
hollandica)
PF00161
(RIP)
5 VAL A  73
TYR A 108
ILE A 156
GLU A 161
ARG A 164
None
GOL  A 281 (-4.4A)
None
None
GOL  A 284 (-3.1A)
0.38A 5z3jA-3mvgA:
32.7
5z3jA-3mvgA:
31.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1


(Streptococcus
pyogenes)
PF01791
(DeoC)
4 TYR A 144
TYR A  90
ILE A 148
GLU A 151
None
1.02A 5z3jA-3myoA:
undetectable
5z3jA-3myoA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o04 BETA-KETO-ACYL
CARRIER PROTEIN
SYNTHASE II


(Listeria
monocytogenes)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
4 VAL A  86
ILE A 239
GLU A 241
ARG A 249
None
0.99A 5z3jA-3o04A:
undetectable
5z3jA-3o04A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oug ASPARTATE
1-DECARBOXYLASE


(Francisella
tularensis)
PF02261
(Asp_decarbox)
4 TYR A  58
VAL A  59
TYR A  22
ILE A  60
None
1.04A 5z3jA-3ougA:
undetectable
5z3jA-3ougA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uhj PROBABLE GLYCEROL
DEHYDROGENASE


(Sinorhizobium
meliloti)
PF00465
(Fe-ADH)
4 TYR A  47
ILE A  35
GLU A  40
ARG A  37
None
0.96A 5z3jA-3uhjA:
undetectable
5z3jA-3uhjA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vpp C-TYPE LECTIN DOMAIN
FAMILY 9 MEMBER A


(Homo sapiens)
PF00059
(Lectin_C)
4 VAL A 214
TYR A 125
ILE A 160
GLU A 156
None
None
None
CA  A 301 (-2.4A)
1.04A 5z3jA-3vppA:
undetectable
5z3jA-3vppA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vrb FLAVOPROTEIN SUBUNIT
OF COMPLEX II


(Ascaris suum)
PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C)
4 TYR A 310
ILE A 329
GLU A 330
ARG A 335
None
0.70A 5z3jA-3vrbA:
undetectable
5z3jA-3vrbA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a1g MITOTIC CHECKPOINT
SERINE/THREONINE-PRO
TEIN KINASE BUB1


(Homo sapiens)
PF08311
(Mad3_BUB1_I)
4 VAL A  34
TYR A  71
ILE A  31
GLU A  28
None
1.07A 5z3jA-4a1gA:
undetectable
5z3jA-4a1gA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gf8 PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN


(Vibrio cholerae)
PF00496
(SBP_bac_5)
4 VAL A 522
TYR A 184
GLU A  35
ARG A  51
None
1.01A 5z3jA-4gf8A:
undetectable
5z3jA-4gf8A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h7l UNCHARACTERIZED
PROTEIN


(Planctopirus
limnophila)
no annotation 4 VAL A  99
TYR A  67
ILE A  95
GLU A  65
None
None
None
CU  A 201 (-2.4A)
0.95A 5z3jA-4h7lA:
undetectable
5z3jA-4h7lA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4imv RICIN

(Ricinus
communis)
PF00161
(RIP)
4 VAL A  81
TYR A 123
ILE A 172
GLU A 177
None
0.60A 5z3jA-4imvA:
18.7
5z3jA-4imvA:
28.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN


(Viscum album)
PF00161
(RIP)
5 TYR A  76
VAL A  77
ILE A 160
GLU A 165
ARG A 168
H35  A 305 (-4.2A)
None
H35  A 305 ( 4.5A)
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
0.54A 5z3jA-4jkxA:
35.4
5z3jA-4jkxA:
40.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jwo PHOSPHATE BINDING
PROTEIN


(Planctopirus
limnophila)
PF12727
(PBP_like)
4 VAL A 109
ILE A  60
GLU A 296
ARG A 294
None
1.07A 5z3jA-4jwoA:
undetectable
5z3jA-4jwoA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE


(Campylobacter
jejuni)
PF01053
(Cys_Met_Meta_PP)
4 VAL A 196
TYR A 332
ILE A 163
GLU A 164
None
0.98A 5z3jA-4oc9A:
undetectable
5z3jA-4oc9A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pcs ALPHA-L-FUCOSIDASE

(Bacteroides
thetaiotaomicron)
PF01120
(Alpha_L_fucos)
4 TYR A 156
VAL A 151
ILE A 160
GLU A 163
None
0.94A 5z3jA-4pcsA:
undetectable
5z3jA-4pcsA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q1j POLYKETIDE
BIOSYNTHESIS
ENOYL-COA ISOMERASE
PKSI


(Bacillus
subtilis)
PF00378
(ECH_1)
4 VAL A 146
TYR A 165
ILE A 158
GLU A 157
None
EDO  A 303 (-4.8A)
None
EDO  A 303 ( 4.6A)
0.93A 5z3jA-4q1jA:
undetectable
5z3jA-4q1jA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q66 PROTEIN BCH1

(Saccharomyces
cerevisiae)
no annotation 4 VAL K 189
TYR K 146
ILE K 192
GLU K 195
None
1.05A 5z3jA-4q66K:
undetectable
5z3jA-4q66K:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rxe FARNESYL
PYROPHOSPHATE
SYNTHASE


(Trypanosoma
brucei)
PF00348
(polyprenyl_synt)
4 VAL A 355
ILE A 341
GLU A 342
ARG A 345
None
0.97A 5z3jA-4rxeA:
undetectable
5z3jA-4rxeA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbq QDE-2-INTERACTING
PROTEIN


(Neurospora
crassa)
no annotation 4 VAL A 441
TYR A 460
ILE A 426
GLU A 427
None
1.03A 5z3jA-4wbqA:
undetectable
5z3jA-4wbqA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzo PUTATIVE ACYL-COA
ACYLTRANSFERASE


(Sulfurisphaera
tokodaii)
PF00108
(Thiolase_N)
PF02803
(Thiolase_C)
4 VAL A 296
TYR A 142
ILE A 278
GLU A 282
None
0.97A 5z3jA-4yzoA:
undetectable
5z3jA-4yzoA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zk7 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA


(Thermus
thermophilus)
PF03091
(CutA1)
4 TYR M  77
VAL M  79
TYR M  41
GLU M  43
None
0.94A 5z3jA-4zk7M:
undetectable
5z3jA-4zk7M:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zq0 14-3-3 PROTEIN

(Giardia
intestinalis)
PF00244
(14-3-3)
4 TYR A 127
VAL A 124
ILE A 163
GLU A 162
None
0.74A 5z3jA-4zq0A:
undetectable
5z3jA-4zq0A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aa5 NIFE-HYDROGENASE
LARGE SUBUNIT, HOFG


(Cupriavidus
necator)
PF00374
(NiFeSe_Hases)
4 TYR C 253
ILE C 446
GLU C 447
ARG C 450
None
0.98A 5z3jA-5aa5C:
undetectable
5z3jA-5aa5C:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bob TRANSLATION
INITIATION FACTOR 2
(IF-2 GTPASE)


(Streptococcus
suis)
no annotation 4 TYR A 295
VAL A 211
TYR A 237
ILE A 218
None
1.07A 5z3jA-5bobA:
undetectable
5z3jA-5bobA:
23.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ddz RICIN

(Ricinus
communis)
PF00161
(RIP)
5 VAL A  81
TYR A 123
ILE A 172
GLU A 177
ARG A 180
None
0.38A 5z3jA-5ddzA:
35.6
5z3jA-5ddzA:
41.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3


(Homo sapiens)
PF04153
(NOT2_3_5)
4 TYR C 744
ILE C 715
GLU C 720
ARG C 708
None
0.96A 5z3jA-5fu6C:
undetectable
5z3jA-5fu6C:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hjl TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE


(Streptococcus
porcinus)
PF01791
(DeoC)
4 TYR A 144
TYR A  90
ILE A 148
GLU A 151
None
1.00A 5z3jA-5hjlA:
undetectable
5z3jA-5hjlA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5irc RHO
GTPASE-ACTIVATING
PROTEIN 35


(Rattus
norvegicus)
PF00620
(RhoGAP)
4 VAL A1375
ILE A1269
GLU A1273
ARG A1381
None
0.82A 5z3jA-5ircA:
undetectable
5z3jA-5ircA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6n PROTEIN BMH1

(Saccharomyces
cerevisiae)
no annotation 4 TYR A 124
VAL A 121
ILE A 160
GLU A 159
None
0.85A 5z3jA-5n6nA:
undetectable
5z3jA-5n6nA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ue8 PROTEIN UNC-13
HOMOLOG A


(Rattus
norvegicus)
PF00130
(C1_1)
PF00168
(C2)
PF06292
(DUF1041)
PF10540
(Membr_traf_MHD)
4 VAL A1395
ILE A1325
GLU A1326
ARG A1401
None
0.85A 5z3jA-5ue8A:
undetectable
5z3jA-5ue8A:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vj1 MDCA

(Pseudomonas
aeruginosa)
PF16957
(Mal_decarbox_Al)
4 VAL A 306
TYR A 321
ILE A 301
GLU A 302
None
0.99A 5z3jA-5vj1A:
undetectable
5z3jA-5vj1A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN


(Vibrio harveyi)
no annotation 4 VAL A 523
TYR A 185
GLU A  36
ARG A  52
None
1.03A 5z3jA-5yqwA:
undetectable
5z3jA-5yqwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aoo MALATE DEHYDROGENASE

(Haemophilus
influenzae)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 VAL A 125
TYR A 138
GLU A 254
ARG A 261
None
0.90A 5z3jA-6aooA:
undetectable
5z3jA-6aooA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bev THIOSULFATE
SULFURTRANSFERASE/RH
ODANESE-LIKE
DOMAIN-CONTAINING
PROTEIN 1


(Homo sapiens)
no annotation 4 VAL A  26
TYR A  63
ILE A  43
GLU A  47
None
1.07A 5z3jA-6bevA:
undetectable
5z3jA-6bevA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8


(Homo sapiens)
no annotation 4 TYR A 319
VAL A 318
ILE A 315
GLU A  70
None
0.97A 5z3jA-6bszA:
undetectable
5z3jA-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6t HUMAN GABA-A
RECEPTOR SUBUNIT
GAMMA-2


(Homo sapiens)
no annotation 4 TYR E 220
VAL E 221
ILE E 179
GLU E 178
None
1.07A 5z3jA-6d6tE:
undetectable
5z3jA-6d6tE:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dw1 -

(-)
no annotation 4 TYR D 220
VAL D 221
ILE D 179
GLU D 178
None
0.94A 5z3jA-6dw1D:
undetectable
5z3jA-6dw1D:
undetectable