SIMILAR PATTERNS OF AMINO ACIDS FOR 5YW0_A_ACTA412

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cew CYSTATIN

(Gallus gallus) 		PF00031
(Cystatin) 		3 LYS I  73
ASN I  33
SER I  42
 None
 1.18A 5yw0A-1cewI:
1.1		 5yw0A-1cewI:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cy9 DNA TOPOISOMERASE I

(Escherichia
coli) 		PF01131
(Topoisom_bac) 		3 LYS A 365
ASN A 326
SER A 357
 None
 1.13A 5yw0A-1cy9A:
0.0		 5yw0A-1cy9A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ems NIT-FRAGILE
HISTIDINE TRIAD
FUSION PROTEIN

(Caenorhabditis
elegans) 		PF00795
(CN_hydrolase)
PF01230
(HIT) 		3 LYS A 127
ASN A 110
SER A 147
 EMC  A 451 (-3.0A)
EMC  A 453 (-3.2A)
EMC  A 453 (-3.4A)
 1.26A 5yw0A-1emsA:
0.0		 5yw0A-1emsA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1exs BETA-LACTOGLOBULIN

(Sus scrofa) 		PF00061
(Lipocalin) 		3 LYS A  83
ASN A  90
SER A 110
 None
 1.08A 5yw0A-1exsA:
0.0		 5yw0A-1exsA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f76 DIHYDROOROTATE
DEHYDROGENASE
(QUINONE)

(Escherichia
coli) 		PF01180
(DHO_dh) 		3 LYS A 217
ASN A 172
SER A 175
 FMN  A1337 (-2.8A)
ORO  A1338 ( 3.2A)
ORO  A1338 (-3.0A)
 1.25A 5yw0A-1f76A:
0.0		 5yw0A-1f76A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f7u ARGINYL-TRNA
SYNTHETASE

(Saccharomyces
cerevisiae) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		3 LYS A   2
ASN A   6
SER A   9
 None
 1.11A 5yw0A-1f7uA:
0.0		 5yw0A-1f7uA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i74 PROBABLE
MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE

(Streptococcus
mutans) 		PF01368
(DHH)
PF02833
(DHHA2) 		3 LYS A 273
ASN A 270
SER A 212
 None
 0.94A 5yw0A-1i74A:
0.0		 5yw0A-1i74A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jal YCHF PROTEIN

(Haemophilus
influenzae) 		PF01926
(MMR_HSR1)
PF06071
(YchF-GTPase_C) 		3 LYS A  24
ASN A  20
SER A 242
 None
 1.20A 5yw0A-1jalA:
0.0		 5yw0A-1jalA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lkj CALMODULIN

(Saccharomyces
cerevisiae) 		PF13499
(EF-hand_7) 		3 LYS A  77
ASN A  79
SER A   2
 None
 0.98A 5yw0A-1lkjA:
undetectable		 5yw0A-1lkjA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nr6 CYTOCHROME P450 2C5

(Oryctolagus
cuniculus) 		PF00067
(p450) 		3 LYS A  72
ASN A 218
SER A  99
 None
 1.27A 5yw0A-1nr6A:
0.0		 5yw0A-1nr6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pk0 CALMODULIN-SENSITIVE
ADENYLATE CYCLASE

(Bacillus
anthracis) 		PF03497
(Anthrax_toxA) 		3 LYS A 404
ASN A 451
SER A 447
 None
 1.10A 5yw0A-1pk0A:
undetectable		 5yw0A-1pk0A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rtg HUMAN GELATINASE A

(Homo sapiens) 		PF00045
(Hemopexin) 		3 LYS A 576
ASN A 642
SER A 629
 None
 1.19A 5yw0A-1rtgA:
undetectable		 5yw0A-1rtgA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v72 ALDOLASE

(Pseudomonas
putida) 		PF01212
(Beta_elim_lyase) 		3 LYS A 268
ASN A 265
SER A  21
 None
 1.25A 5yw0A-1v72A:
undetectable		 5yw0A-1v72A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpl ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Thermotoga
maritima) 		PF00005
(ABC_tran) 		3 LYS A 142
ASN A 169
SER A 136
 None
 1.25A 5yw0A-1vplA:
undetectable		 5yw0A-1vplA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyp CALPONIN 1

(Homo sapiens) 		PF00307
(CH) 		3 LYS A   9
ASN A   8
SER A   5
 None
 1.27A 5yw0A-1wypA:
undetectable		 5yw0A-1wypA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz9 MASPIN PRECURSOR

(Homo sapiens) 		PF00079
(Serpin) 		3 LYS A 371
ASN A  27
SER A 374
 CME  A  20 ( 3.8A)
CME  A 373 (-3.7A)
CME  A 373 ( 3.5A)
 1.15A 5yw0A-1wz9A:
undetectable		 5yw0A-1wz9A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2abq FRUCTOSE 1-PHOSPHATE
KINASE

(Bacillus
halodurans) 		PF00294
(PfkB) 		3 LYS A  92
ASN A  90
SER A  10
 None
 1.25A 5yw0A-2abqA:
undetectable		 5yw0A-2abqA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3q GREEN FLUORESCENT
PROTEIN

(Aequorea
victoria) 		PF01353
(GFP) 		3 LYS A 140
ASN A 135
SER A 175
 None
MG  A 701 (-3.4A)
MG  A 701 ( 4.7A)
 1.26A 5yw0A-2b3qA:
undetectable		 5yw0A-2b3qA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0v METHANOL
DEHYDROGENASE LARGE
SUBUNIT

(Hyphomicrobium
denitrificans) 		PF01011
(PQQ)
PF13360
(PQQ_2) 		3 LYS A 126
ASN A  73
SER A  69
 None
 1.01A 5yw0A-2d0vA:
undetectable		 5yw0A-2d0vA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gti REPLICASE
POLYPROTEIN 1AB

(Murine
coronavirus) 		PF06471
(NSP11) 		3 LYS A 353
ASN A  74
SER A 302
 None
 1.24A 5yw0A-2gtiA:
undetectable		 5yw0A-2gtiA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2khg PLNJ

(Lactobacillus
plantarum) 		no annotation 3 LYS A   4
ASN A   5
SER A   9
 None
 1.21A 5yw0A-2khgA:
undetectable		 5yw0A-2khgA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l02 UNCHARACTERIZED
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF10771
(DUF2582) 		3 LYS A  12
ASN A   9
SER A  38
 None
 0.72A 5yw0A-2l02A:
undetectable		 5yw0A-2l02A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mzv CYSTATIN

(Sesamum indicum) 		PF16845
(SQAPI) 		3 LYS A 192
ASN A 190
SER A 158
 None
 0.93A 5yw0A-2mzvA:
undetectable		 5yw0A-2mzvA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvv ACETYL-COA
HYDROLASE/TRANSFERAS
E FAMILY PROTEIN

(Porphyromonas
gingivalis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		3 LYS A  33
ASN A  31
SER A  24
 LYS  A  33 ( 0.0A)
ASN  A  31 ( 0.6A)
SER  A  24 ( 0.0A)
 1.17A 5yw0A-2nvvA:
undetectable		 5yw0A-2nvvA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqk NEUROPILIN-2

(Homo sapiens) 		PF00431
(CUB)
PF00754
(F5_F8_type_C) 		3 LYS A  67
ASN A  65
SER A 146
 None
 1.00A 5yw0A-2qqkA:
undetectable		 5yw0A-2qqkA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qy1 PECTATE LYASE II

(Xanthomonas
campestris) 		PF00544
(Pec_lyase_C) 		3 LYS A  92
ASN A  93
SER A 146
 None
 1.23A 5yw0A-2qy1A:
undetectable		 5yw0A-2qy1A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qza SECRETED EFFECTOR
PROTEIN

(Salmonella
enterica) 		PF13599
(Pentapeptide_4)
PF13979
(SopA_C)
PF13981
(SopA) 		3 LYS A 354
ASN A 352
SER A 699
 None
 1.25A 5yw0A-2qzaA:
undetectable		 5yw0A-2qzaA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xka FTSZ/TUBULIN-RELATED
PROTEIN

(Bacillus
thuringiensis) 		PF00091
(Tubulin) 		3 LYS A 335
ASN A 262
SER A 260
 None
 1.29A 5yw0A-2xkaA:
undetectable		 5yw0A-2xkaA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zvs UNCHARACTERIZED
FERREDOXIN-LIKE
PROTEIN YFHL

(Escherichia
coli) 		PF00037
(Fer4) 		3 LYS A  36
ASN A  33
SER A  24
 None
 1.06A 5yw0A-2zvsA:
undetectable		 5yw0A-2zvsA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agr NUCLEOSIDE
TRIPHOSPHATE
HYDROLASE

(Neospora
caninum) 		PF01150
(GDA1_CD39) 		3 LYS A 364
ASN A 363
SER A 342
 None
 1.29A 5yw0A-3agrA:
undetectable		 5yw0A-3agrA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cfx UPF0100 PROTEIN
MA_0280

(Methanosarcina
acetivorans) 		PF13531
(SBP_bac_11) 		3 LYS A 276
ASN A 273
SER A 176
 None
 0.99A 5yw0A-3cfxA:
undetectable		 5yw0A-3cfxA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csk PROBABLE
DIPEPTIDYL-PEPTIDASE
3

(Saccharomyces
cerevisiae) 		PF03571
(Peptidase_M49) 		3 LYS A 108
ASN A 100
SER A  52
 None
 1.07A 5yw0A-3cskA:
undetectable		 5yw0A-3cskA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dla GLUTAMINE-DEPENDENT
NAD(+) SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		3 LYS A 414
ASN A 411
SER A 536
 None
 1.14A 5yw0A-3dlaA:
undetectable		 5yw0A-3dlaA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ho6 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80) 		3 LYS A  35
ASN A  61
SER A  65
 IHP  A 270 ( 3.3A)
None
None
 1.07A 5yw0A-3ho6A:
undetectable		 5yw0A-3ho6A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6r DIHYDROOROTATE
DEHYDROGENASE
HOMOLOG,
MITOCHONDRIAL

(Plasmodium
falciparum) 		PF01180
(DHO_dh) 		3 LYS A 429
ASN A 342
SER A 345
 FMN  A1002 (-2.8A)
ORO  A1003 ( 3.5A)
ORO  A1003 (-3.2A)
 1.24A 5yw0A-3i6rA:
undetectable		 5yw0A-3i6rA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwf TRANSCRIPTION
REGULATOR RPIR
FAMILY

(Staphylococcus
epidermidis) 		PF01418
(HTH_6) 		3 LYS A  21
ASN A  18
SER A  51
 None
 1.05A 5yw0A-3iwfA:
undetectable		 5yw0A-3iwfA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k6x SOLUTE-BINDING
PROTEIN MA_0280

(Methanosarcina
acetivorans) 		PF13531
(SBP_bac_11) 		3 LYS A 276
ASN A 273
SER A 176
 None
 1.02A 5yw0A-3k6xA:
undetectable		 5yw0A-3k6xA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lhc CYANOVIRIN-N

(Nostoc
ellipsosporum) 		PF08881
(CVNH) 		3 LYS A  83
ASN A  85
SER A  66
 None
 1.27A 5yw0A-3lhcA:
undetectable		 5yw0A-3lhcA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ns5 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT B

(Saccharomyces
cerevisiae) 		PF00076
(RRM_1) 		3 LYS A 139
ASN A 135
SER A 133
 None
 1.15A 5yw0A-3ns5A:
undetectable		 5yw0A-3ns5A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppl ASPARTATE
AMINOTRANSFERASE

(Corynebacterium
glutamicum) 		PF12897
(Aminotran_MocR) 		3 LYS A 391
ASN A 392
SER A 353
 None
 1.10A 5yw0A-3pplA:
undetectable		 5yw0A-3pplA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3srz TOXIN A

(Clostridioides
difficile) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		3 LYS A  44
ASN A  41
SER A  88
 None
 1.27A 5yw0A-3srzA:
undetectable		 5yw0A-3srzA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vnf MEMBRANE-ASSOCIATED
PROTEIN VP24

(Sudan
ebolavirus) 		PF06389
(Filo_VP24) 		3 LYS A  52
ASN A  50
SER A 225
 None
 1.17A 5yw0A-3vnfA:
undetectable		 5yw0A-3vnfA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vse PUTATIVE
UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF10672
(Methyltrans_SAM) 		3 LYS A 382
ASN A 333
SER A 296
 None
 1.15A 5yw0A-3vseA:
undetectable		 5yw0A-3vseA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w77 FMN-DEPENDENT
NADH-AZOREDUCTASE

(Bacillus sp.
B29) 		PF02525
(Flavodoxin_2) 		3 LYS A   8
ASN A  10
SER A  19
 None
FMN  A 301 (-3.4A)
FMN  A 301 (-2.6A)
 1.22A 5yw0A-3w77A:
undetectable		 5yw0A-3w77A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aca TRANSLATION
ELONGATION FACTOR
SELB

(Methanococcus
maripaludis) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		3 LYS A 187
ASN A 208
SER A  78
 None
 1.25A 5yw0A-4acaA:
undetectable		 5yw0A-4acaA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bqi ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC

(Arabidopsis
thaliana) 		PF00343
(Phosphorylase) 		3 LYS A 542
ASN A 545
SER A 499
 None
 1.16A 5yw0A-4bqiA:
undetectable		 5yw0A-4bqiA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4btg MAJOR INNER PROTEIN
P1

(Pseudomonas
virus phi6) 		no annotation 3 LYS A  58
ASN A  60
SER A 159
 None
 1.29A 5yw0A-4btgA:
undetectable		 5yw0A-4btgA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		3 LYS A 319
ASN A 347
SER A 169
 None
 1.30A 5yw0A-4c41A:
undetectable		 5yw0A-4c41A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgn GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE

(Leishmania
major) 		PF01233
(NMT)
PF02799
(NMT_C) 		3 LYS A 318
ASN A 315
SER A 353
 None
 1.15A 5yw0A-4cgnA:
undetectable		 5yw0A-4cgnA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eq9 ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN-AMINO ACID
TRANSPORT

(Streptococcus
pneumoniae) 		PF00497
(SBP_bac_3) 		3 LYS A  83
ASN A  45
SER A  47
 None
GSH  A 301 (-3.3A)
None
 1.28A 5yw0A-4eq9A:
undetectable		 5yw0A-4eq9A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f3e CASA

(Thermus
thermophilus) 		PF09481
(CRISPR_Cse1) 		3 LYS A 376
ASN A 373
SER A 449
 None
 1.28A 5yw0A-4f3eA:
undetectable		 5yw0A-4f3eA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjc ENVELOPE
GLYCOPROTEIN

(Rift Valley
fever
phlebovirus) 		PF07245
(Phlebovirus_G2) 		3 LYS A 988
ASN A 986
SER A 898
 None
 1.29A 5yw0A-4hjcA:
undetectable		 5yw0A-4hjcA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifd EXOSOME COMPLEX
COMPONENT RRP43

(Saccharomyces
cerevisiae) 		PF01138
(RNase_PH) 		3 LYS C 358
ASN C 356
SER C 354
 None
 1.09A 5yw0A-4ifdC:
undetectable		 5yw0A-4ifdC:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4je5 AROMATIC/AMINOADIPAT
E AMINOTRANSFERASE 1

(Saccharomyces
cerevisiae) 		PF00155
(Aminotran_1_2) 		3 LYS A 231
ASN A 286
SER A 290
 None
 0.83A 5yw0A-4je5A:
undetectable		 5yw0A-4je5A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jrb GREEN FLUORESCENT
PROTEIN

(Aequorea
victoria;
Blattella
germanica) 		PF01353
(GFP)
PF06757
(Ins_allergen_rp) 		3 LYS A 140
ASN A 135
SER A 175
 None
 1.26A 5yw0A-4jrbA:
undetectable		 5yw0A-4jrbA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k1o CATENIN ALPHA-2

(Mus musculus) 		PF01044
(Vinculin) 		3 LYS A 746
ASN A 790
SER A 793
 None
 1.28A 5yw0A-4k1oA:
undetectable		 5yw0A-4k1oA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kf5 FLUORESCENT PROTEIN
GFP1-9

(synthetic
construct) 		PF01353
(GFP) 		3 LYS A 140
ASN A 135
SER A 175
 None
 1.20A 5yw0A-4kf5A:
undetectable		 5yw0A-4kf5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lg9 F-BOX-LIKE/WD
REPEAT-CONTAINING
PROTEIN TBL1XR1

(Homo sapiens) 		PF00400
(WD40) 		3 LYS A 335
ASN A 320
SER A 318
 UNX  A 605 ( 4.6A)
UNX  A 613 ( 4.5A)
UNX  A 605 ( 3.3A)
 1.22A 5yw0A-4lg9A:
undetectable		 5yw0A-4lg9A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4maf ATP SULFURYLASE

(Glycine max) 		PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		3 LYS A 335
ASN A 128
SER A 130
 None
 1.25A 5yw0A-4mafA:
undetectable		 5yw0A-4mafA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ph9 PROSTAGLANDIN G/H
SYNTHASE 2

(Mus musculus) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		3 LYS A 469
ASN A 465
SER A 463
 None
 1.04A 5yw0A-4ph9A:
undetectable		 5yw0A-4ph9A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pl0 MICROCIN-J25 EXPORT
ATP-BINDING/PERMEASE
PROTEIN MCJD

(Escherichia
coli) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		3 LYS A 453
ASN A 449
SER A 447
 None
 0.94A 5yw0A-4pl0A:
undetectable		 5yw0A-4pl0A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7b CHOLINE KINASE

(Streptococcus
pneumoniae) 		PF01633
(Choline_kinase) 		3 LYS A  40
ASN A  39
SER A  14
 None
 1.06A 5yw0A-4r7bA:
undetectable		 5yw0A-4r7bA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xkq NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Staphylococcus
aureus) 		PF00496
(SBP_bac_5) 		3 LYS A 204
ASN A 199
SER A  14
 None
 1.22A 5yw0A-4xkqA:
undetectable		 5yw0A-4xkqA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xq6 DIHYDROOROTATE
DEHYDROGENASE
(QUINONE)

(Mycobacterium
tuberculosis) 		PF01180
(DHO_dh) 		3 LYS A 212
ASN A 176
SER A 179
 FMN  A 401 (-2.9A)
FMN  A 401 (-3.4A)
FMN  A 401 (-3.6A)
 1.13A 5yw0A-4xq6A:
undetectable		 5yw0A-4xq6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E

(Rattus
norvegicus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		3 LYS A 995
ASN A 991
SER A 544
 None
 1.27A 5yw0A-4yswA:
undetectable		 5yw0A-4yswA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zf4 GREEN FLUORESCENT
PROTEIN

(Aequorea
victoria) 		PF01353
(GFP) 		3 LYS A  90
ASN A  85
SER A 125
 None
 1.18A 5yw0A-4zf4A:
undetectable		 5yw0A-4zf4A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5az4 FLAGELLAR HOOK
SUBUNIT PROTEIN

(Campylobacter
jejuni) 		PF07196
(Flagellin_IN)
PF07559
(FlaE) 		3 LYS A 645
ASN A 654
SER A 728
 None
 0.81A 5yw0A-5az4A:
undetectable		 5yw0A-5az4A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT

(Candidatus
Kuenenia
stuttgartiensis) 		no annotation 3 LYS A 447
ASN A 432
SER A 234
 None
 1.25A 5yw0A-5c2vA:
undetectable		 5yw0A-5c2vA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c6u AMINOTRANSFERASE

(Mycobacterium
tuberculosis) 		PF12897
(Aminotran_MocR) 		3 LYS A 389
ASN A 390
SER A 351
 None
 1.11A 5yw0A-5c6uA:
undetectable		 5yw0A-5c6uA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cfc VP1
VP3

(Cardiovirus B;
Cardiovirus B) 		no annotation
PF00073
(Rhv) 		3 LYS A   1
ASN B 160
SER A  11
 None
 1.08A 5yw0A-5cfcA:
undetectable		 5yw0A-5cfcA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cfc VP1
VP3

(Cardiovirus B;
Cardiovirus B) 		no annotation
PF00073
(Rhv) 		3 LYS A   7
ASN A   4
SER B 158
 None
 1.23A 5yw0A-5cfcA:
undetectable		 5yw0A-5cfcA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cqe MATRIX PROTEIN 1

(Influenza A
virus) 		PF00598
(Flu_M1) 		3 LYS A  95
ASN A  92
SER A 120
 None
 1.10A 5yw0A-5cqeA:
undetectable		 5yw0A-5cqeA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3c DIPEPTIDYL PEPTIDASE
3

(Homo sapiens) 		PF03571
(Peptidase_M49) 		3 LYS A 113
ASN A 105
SER A  53
 None
 0.91A 5yw0A-5e3cA:
undetectable		 5yw0A-5e3cA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eef HDAC6

(Danio rerio) 		PF00850
(Hist_deacetyl) 		3 LYS A 288
ASN A 287
SER A 400
 None
 1.13A 5yw0A-5eefA:
undetectable		 5yw0A-5eefA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g53 ENGINEERED DOMAIN OF
HUMAN G ALPHA S LONG
ISOFORM

(Homo sapiens) 		PF00503
(G-alpha) 		3 LYS C 274
ASN C 278
SER C 352
 None
 1.24A 5yw0A-5g53C:
undetectable		 5yw0A-5g53C:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hde TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 12

(Homo sapiens) 		PF00102
(Y_phosphatase) 		3 LYS A  60
ASN A  58
SER A  86
 None
 1.23A 5yw0A-5hdeA:
undetectable		 5yw0A-5hdeA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikr PROSTAGLANDIN G/H
SYNTHASE 2

(Homo sapiens) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		3 LYS A 468
ASN A 464
SER A 462
 None
 1.07A 5yw0A-5ikrA:
undetectable		 5yw0A-5ikrA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 LYS A  49
ASN A  54
SER A 249
 None
 1.22A 5yw0A-5ip9A:
undetectable		 5yw0A-5ip9A:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxl FLAGELLAR HOOK
PROTEIN FLGE

(Campylobacter
jejuni) 		PF00460
(Flg_bb_rod)
PF06429
(Flg_bbr_C)
PF07196
(Flagellin_IN)
PF07559
(FlaE) 		3 LYS A 631
ASN A 640
SER A 714
 None
 1.28A 5yw0A-5jxlA:
undetectable		 5yw0A-5jxlA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5klf CARBOHYDRATE BINDING
MODULE E1

(uncultured
bacterium) 		no annotation 3 LYS A  19
ASN A  96
SER A  36
 GD  A 109 ( 4.7A)
None
None
 1.28A 5yw0A-5klfA:
undetectable		 5yw0A-5klfA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lx8 SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 LYS A 210
ASN A 281
SER A 285
 None
 1.29A 5yw0A-5lx8A:
undetectable		 5yw0A-5lx8A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nth PUTATIVE
AMINOPEPTIDASE

(Leishmania
major) 		PF00883
(Peptidase_M17) 		3 LYS A 320
ASN A 318
SER A 519
 None
 0.89A 5yw0A-5nthA:
undetectable		 5yw0A-5nthA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o0s GLUCOSYLCERAMIDASE

(Thermoanaerobacterium
xylanolyticum) 		PF04685
(DUF608)
PF12215
(Glyco_hydr_116N)
PF17168
(DUF5127) 		3 LYS A 373
ASN A 377
SER A 244
 None
 1.19A 5yw0A-5o0sA:
undetectable		 5yw0A-5o0sA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o32 COMPLEMENT FACTOR I

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00530
(SRCR) 		3 LYS D 233
ASN D 231
SER D 251
 None
 1.24A 5yw0A-5o32D:
undetectable		 5yw0A-5o32D:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t8y EPOXYQUEUOSINE
REDUCTASE

(Bacillus
subtilis) 		PF08331
(DUF1730)
PF13484
(Fer4_16)
PF13646
(HEAT_2) 		3 LYS A 253
ASN A 250
SER A 165
 None
 1.25A 5yw0A-5t8yA:
undetectable		 5yw0A-5t8yA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vf6 SINGLE CHAIN
VARIABLE FRAGMENT

(Gallus gallus) 		no annotation 3 LYS A  50
ASN A  47
SER A 225
 None
 0.98A 5yw0A-5vf6A:
undetectable		 5yw0A-5vf6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgz 26S PROTEASOME
REGULATORY SUBUNIT
10B
26S PROTEASOME
REGULATORY SUBUNIT
6A

(Homo sapiens;
Homo sapiens) 		no annotation
no annotation 		3 LYS F  79
ASN F  76
SER E  43
 None
 1.17A 5yw0A-5vgzF:
undetectable		 5yw0A-5vgzF:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w0a GLUCANASE

(Trichoderma
harzianum) 		no annotation 3 LYS A   1
ASN A 160
SER A 168
 GLN  A   1 ( 0.0A)
ASN  A 160 ( 0.6A)
SER  A 168 ( 0.0A)
 1.13A 5yw0A-5w0aA:
undetectable		 5yw0A-5w0aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wg6 HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2,POLYCOMB
PROTEIN SUZ12
(E.C.2.1.1.43)
CHIMERA

(Homo sapiens) 		no annotation 3 LYS A 261
ASN A2607
SER A 280
 None
 1.05A 5yw0A-5wg6A:
undetectable		 5yw0A-5wg6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wln TYPE II SECRETION
SYSTEM PROTEIN D

(Pseudomonas
aeruginosa) 		no annotation 3 LYS G 359
ASN G 361
SER G 368
 None
 0.99A 5yw0A-5wlnG:
undetectable		 5yw0A-5wlnG:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wmb DNA REPAIR PROTEIN
REV1

(Saccharomyces
cerevisiae) 		no annotation 3 LYS A 734
ASN A 733
SER A 694
 None
 1.29A 5yw0A-5wmbA:
undetectable		 5yw0A-5wmbA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x59 S PROTEIN

(Middle East
respiratory
syndrome-related
coronavirus) 		PF01601
(Corona_S2)
PF09408
(Spike_rec_bind) 		3 LYS A 698
ASN A 719
SER A 684
 None
 1.18A 5yw0A-5x59A:
undetectable		 5yw0A-5x59A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT

(Komagataella
phaffii) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 LYS A 652
ASN A 649
SER A 556
 None
 1.27A 5yw0A-5xogA:
undetectable		 5yw0A-5xogA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6au6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN G(S) SUBUNIT
ALPHA ISOFORMS SHORT

(Homo sapiens) 		no annotation 3 LYS A 274
ASN A 278
SER A 352
 None
 1.17A 5yw0A-6au6A:
undetectable		 5yw0A-6au6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT C
ALTERNATIVE COMPLEX
III SUBUNIT D

(Flavobacterium
johnsoniae;
Flavobacterium
johnsoniae) 		no annotation
no annotation 		3 LYS D  87
ASN C 158
SER D  98
 None
 1.25A 5yw0A-6btmD:
undetectable		 5yw0A-6btmD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c6k INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 1

(Homo sapiens) 		no annotation 3 LYS A 222
ASN A 218
SER A 250
 None
 0.91A 5yw0A-6c6kA:
undetectable		 5yw0A-6c6kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6e0s -

(-) 		no annotation 3 LYS A  23
ASN A  25
SER A  63
 None
 1.24A 5yw0A-6e0sA:
undetectable		 5yw0A-6e0sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ekv TOXIN COMPLEX
COMPONENT ORF-X2

(Clostridium
botulinum) 		no annotation 3 LYS A 287
ASN A 285
SER A 268
 None
 1.25A 5yw0A-6ekvA:
undetectable		 5yw0A-6ekvA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1

(Homo sapiens) 		no annotation 3 LYS A  64
ASN A  44
SER A 856
 None
 0.81A 5yw0A-6f9nA:
undetectable		 5yw0A-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g4q SUCCINATE--COA
LIGASE [ADP-FORMING]
SUBUNIT BETA,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 3 LYS B 242
ASN B 239
SER B  70
 None
 1.11A 5yw0A-6g4qB:
undetectable		 5yw0A-6g4qB:
undetectable