SIMILAR PATTERNS OF AMINO ACIDS FOR 5YW0_A_ACTA409

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cle CHOLESTEROL ESTERASE

([Candida]
cylindracea) 		PF00135
(COesterase) 		3 ASP A 412
PHE A 517
ARG A 419
 None
 0.90A 5yw0A-1cleA:
0.0		 5yw0A-1cleA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cle CHOLESTEROL ESTERASE

([Candida]
cylindracea) 		PF00135
(COesterase) 		3 ASP A 412
PHE A 517
ARG A 420
 None
 1.15A 5yw0A-1cleA:
0.0		 5yw0A-1cleA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cr8 PROTEIN (LOW DENSITY
LIPOPROTEIN RECEPTOR
RELATED PROTEIN)

(Homo sapiens) 		PF00057
(Ldl_recept_a) 		3 ASP A  34
PHE A  11
ARG A  14
 None
 1.09A 5yw0A-1cr8A:
undetectable		 5yw0A-1cr8A:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1crl LIPASE

(Diutina rugosa) 		PF00135
(COesterase) 		3 ASP A 412
PHE A 517
ARG A 419
 None
 0.89A 5yw0A-1crlA:
0.0		 5yw0A-1crlA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1crl LIPASE

(Diutina rugosa) 		PF00135
(COesterase) 		3 ASP A 412
PHE A 517
ARG A 420
 None
 1.10A 5yw0A-1crlA:
0.0		 5yw0A-1crlA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cte CATHEPSIN B

(Rattus
norvegicus) 		PF00112
(Peptidase_C1) 		3 ASP A   6
PHE A 230
ARG A 202
 None
 1.05A 5yw0A-1cteA:
0.0		 5yw0A-1cteA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz7 LIPASE 2

(Diutina rugosa) 		PF00135
(COesterase) 		3 ASP A 412
PHE A 517
ARG A 419
 None
 0.92A 5yw0A-1gz7A:
0.0		 5yw0A-1gz7A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz7 LIPASE 2

(Diutina rugosa) 		PF00135
(COesterase) 		3 ASP A 412
PHE A 517
ARG A 420
 None
 1.11A 5yw0A-1gz7A:
0.0		 5yw0A-1gz7A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hfe PROTEIN (FE-ONLY
HYDROGENASE
(E.C.1.18.99.1)
(LARGER SUBUNIT))
PROTEIN (FE-ONLY
HYDROGENASE
(E.C.1.18.99.1)
(SMALLER SUBUNIT))

(Desulfovibrio
vulgaris;
Desulfovibrio
vulgaris) 		PF02906
(Fe_hyd_lg_C)
PF13237
(Fer4_10)
PF02256
(Fe_hyd_SSU) 		3 ASP L 150
PHE S  57
ARG L 282
 None
 0.84A 5yw0A-1hfeL:
0.0		 5yw0A-1hfeL:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR

(Homo sapiens) 		PF01094
(ANF_receptor) 		3 ASP A 318
PHE A 287
ARG A 281
 None
 0.91A 5yw0A-1jdpA:
0.0		 5yw0A-1jdpA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n4o L2 BETA-LACTAMASE

(Stenotrophomonas
maltophilia) 		PF13354
(Beta-lactamase2) 		3 ASP A 242
PHE A 172
ARG A  43
 None
 1.11A 5yw0A-1n4oA:
0.0		 5yw0A-1n4oA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qdq CATHEPSIN B

(Bos taurus) 		PF00112
(Peptidase_C1) 		3 ASP A   6
PHE A 230
ARG A 202
 None
 1.12A 5yw0A-1qdqA:
0.0		 5yw0A-1qdqA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhb HALOPEROXIDASE

(Corallina
officinalis) 		PF01569
(PAP2) 		3 ASP A 458
PHE A 310
ARG A 289
 None
 1.16A 5yw0A-1qhbA:
undetectable		 5yw0A-1qhbA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r4v HYPOTHETICAL PROTEIN
AQ_328

(Aquifex
aeolicus) 		PF09123
(DUF1931) 		3 ASP A 103
PHE A  97
ARG A 132
 None
 1.15A 5yw0A-1r4vA:
undetectable		 5yw0A-1r4vA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xxg ENTEROTOXIN

(Staphylococcus
aureus) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		3 ASP A 194
PHE A 209
ARG A 159
 None
 1.06A 5yw0A-1xxgA:
undetectable		 5yw0A-1xxgA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z48 PROBABLE
NADH-DEPENDENT
FLAVIN
OXIDOREDUCTASE YQJM

(Bacillus
subtilis) 		PF00724
(Oxidored_FMN) 		3 ASP A 220
PHE A 234
ARG A 193
 None
 0.90A 5yw0A-1z48A:
undetectable		 5yw0A-1z48A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zrr E-2/E-2' PROTEIN

(Klebsiella
oxytoca) 		PF03079
(ARD) 		3 ASP A 157
PHE A  92
ARG A 154
 None
None
NI  A 180 ( 4.7A)
 1.03A 5yw0A-1zrrA:
4.0		 5yw0A-1zrrA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4i AVIDIN

(Gallus gallus) 		PF01382
(Avidin) 		3 ASP A  53
PHE A 150
ARG A  45
 None
 1.16A 5yw0A-2c4iA:
undetectable		 5yw0A-2c4iA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4i AVIDIN

(Gallus gallus) 		PF01382
(Avidin) 		3 ASP A 174
PHE A  29
ARG A 166
 None
 1.14A 5yw0A-2c4iA:
undetectable		 5yw0A-2c4iA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cw9 TRANSLOCASE OF INNER
MITOCHONDRIAL
MEMBRANE

(Homo sapiens) 		PF04280
(Tim44) 		3 ASP A 373
PHE A 272
ARG A 418
 None
 0.89A 5yw0A-2cw9A:
undetectable		 5yw0A-2cw9A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fek LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE WZB

(Escherichia
coli) 		PF01451
(LMWPc) 		3 ASP A 115
PHE A 124
ARG A 118
 None
 1.14A 5yw0A-2fekA:
undetectable		 5yw0A-2fekA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nz9 BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		3 ASP A 275
PHE A 282
ARG A 241
 None
 1.05A 5yw0A-2nz9A:
undetectable		 5yw0A-2nz9A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nz9 BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		3 ASP A 461
PHE A 423
ARG A 555
 None
 0.87A 5yw0A-2nz9A:
undetectable		 5yw0A-2nz9A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odt INOSITOL-TETRAKISPHO
SPHATE 1-KINASE

(Homo sapiens) 		PF05770
(Ins134_P3_kin) 		3 ASP X 281
PHE X 201
ARG X 212
 None
 1.03A 5yw0A-2odtX:
undetectable		 5yw0A-2odtX:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbh PROCATHEPSIN B

(Homo sapiens) 		PF00112
(Peptidase_C1)
PF08127
(Propeptide_C1) 		3 ASP A   6
PHE A 230
ARG A 202
 None
 1.14A 5yw0A-2pbhA:
undetectable		 5yw0A-2pbhA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pqi RIBOSOME-INACTIVATIN
G PROTEIN 3

(Zea mays) 		PF00161
(RIP) 		3 ASP A 219
PHE A  27
ARG A 146
 None
 1.15A 5yw0A-2pqiA:
undetectable		 5yw0A-2pqiA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pwh SUCROSE ISOMERASE

([Pseudomonas]
mesoacidophila) 		PF00128
(Alpha-amylase)
PF11941
(DUF3459) 		3 ASP A 393
PHE A 222
ARG A 291
 None
 1.03A 5yw0A-2pwhA:
undetectable		 5yw0A-2pwhA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhq PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Staphylococcus
haemolyticus) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		3 ASP B 461
PHE B 442
ARG B 458
 None
 1.06A 5yw0A-2rhqB:
undetectable		 5yw0A-2rhqB:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III

(Cinnamomum
camphora) 		PF00161
(RIP)
PF00652
(Ricin_B_lectin) 		3 ASP A 286
PHE A 249
ARG A 252
 None
 0.76A 5yw0A-2vlcA:
undetectable		 5yw0A-2vlcA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ycd GLUTATHIONE
S-TRANSFERASE

(Agrobacterium
tumefaciens) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		3 ASP A  27
PHE A 217
ARG A 186
 None
 1.15A 5yw0A-2ycdA:
undetectable		 5yw0A-2ycdA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium) 		PF13469
(Sulfotransfer_3) 		3 ASP A  59
PHE A   4
ARG A  20
 None
 1.13A 5yw0A-2z6vA:
undetectable		 5yw0A-2z6vA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY

(Thermus
thermophilus) 		no annotation 3 ASP C 130
PHE C 123
ARG C 156
 None
 1.09A 5yw0A-3anpC:
undetectable		 5yw0A-3anpC:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3av6 DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Mus musculus) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC)
PF12047
(DNMT1-RFD) 		3 ASP A1070
PHE A1088
ARG A 999
 None
 0.90A 5yw0A-3av6A:
undetectable		 5yw0A-3av6A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cze SUCROSE HYDROLASE

(Xanthomonas
citri) 		PF00128
(Alpha-amylase) 		3 ASP A 392
PHE A 140
ARG A 278
 TRS  A6646 (-2.6A)
TRS  A6646 (-3.5A)
TRS  A6646 ( 4.0A)
 1.15A 5yw0A-3czeA:
undetectable		 5yw0A-3czeA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzt D7 PROTEIN

(Aedes aegypti) 		PF01395
(PBP_GOBP) 		3 ASP A 207
PHE A  11
ARG A 267
 None
GOL  A 308 (-4.7A)
None
 1.15A 5yw0A-3dztA:
undetectable		 5yw0A-3dztA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e82 PUTATIVE
OXIDOREDUCTASE

(Klebsiella
pneumoniae) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 ASP A 140
PHE A 163
ARG A 135
 None
 0.82A 5yw0A-3e82A:
undetectable		 5yw0A-3e82A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eb7 INSECTICIDAL
DELTA-ENDOTOXIN
CRY8EA1

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		3 ASP A 501
PHE A 340
ARG A 478
 None
 1.16A 5yw0A-3eb7A:
undetectable		 5yw0A-3eb7A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ep1 PGRP-HD -
PEPTIDOGLYCAN
RECOGNITION PROTEIN
HOMOLOGUE

(Alvinella
pompejana) 		PF01510
(Amidase_2) 		3 ASP A 100
PHE A 103
ARG A 179
 None
 1.16A 5yw0A-3ep1A:
undetectable		 5yw0A-3ep1A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3euh CHROMOSOME PARTITION
PROTEIN MUKF

(Escherichia
coli) 		PF03882
(KicB)
PF17192
(MukF_M)
PF17193
(MukF_C) 		3 ASP A  27
PHE A  56
ARG A  73
 None
 0.92A 5yw0A-3euhA:
undetectable		 5yw0A-3euhA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h55 ALPHA-N-ACETYLGALACT
OSAMINIDASE

(Homo sapiens) 		PF16499
(Melibiase_2)
PF17450
(Melibiase_2_C) 		3 ASP A  45
PHE A  36
ARG A 287
 None
 1.13A 5yw0A-3h55A:
undetectable		 5yw0A-3h55A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kxp ALPHA-(N-ACETYLAMINO
METHYLENE)SUCCINIC
ACID HYDROLASE

(Mesorhizobium
loti) 		PF12697
(Abhydrolase_6) 		3 ASP A 277
PHE A  59
ARG A 124
 None
 0.96A 5yw0A-3kxpA:
undetectable		 5yw0A-3kxpA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p4s FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT

(Escherichia
coli) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		3 ASP A 364
PHE A 375
ARG A 413
 None
 1.04A 5yw0A-3p4sA:
undetectable		 5yw0A-3p4sA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pe5 UNCHARACTERIZED
PROTEIN

([Clostridium]
leptum) 		PF03816
(LytR_cpsA_psr) 		3 ASP A 266
PHE A 258
ARG A 324
 None
 1.05A 5yw0A-3pe5A:
undetectable		 5yw0A-3pe5A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qbt RAS-RELATED PROTEIN
RAB-8A
INOSITOL
POLYPHOSPHATE
5-PHOSPHATASE OCRL-1

(Homo sapiens;
Homo sapiens) 		PF00071
(Ras)
no annotation 		3 ASP B 549
PHE A 163
ARG A  48
 None
 1.12A 5yw0A-3qbtB:
undetectable		 5yw0A-3qbtB:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rj8 CARBOHYDRATE OXIDASE

(Microdochium
nivale) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		3 ASP A 430
PHE A 403
ARG A  32
 None
 1.03A 5yw0A-3rj8A:
undetectable		 5yw0A-3rj8A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9v ABIETADIENE
SYNTHASE,
CHLOROPLASTIC

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		3 ASP A 369
PHE A 599
ARG A 828
 None
 0.93A 5yw0A-3s9vA:
undetectable		 5yw0A-3s9vA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3som METHYLMALONIC
ACIDURIA AND
HOMOCYSTINURIA TYPE
C PROTEIN

(Homo sapiens) 		PF16690
(MMACHC) 		3 ASP A  77
PHE A 223
ARG A 161
 None
FLC  A 501 (-3.9A)
FLC  A 501 (-2.6A)
 0.82A 5yw0A-3somA:
undetectable		 5yw0A-3somA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tk3 CYTOCHROME P450 2B4

(Oryctolagus
cuniculus) 		PF00067
(p450) 		3 ASP A 166
PHE A 203
ARG A 473
 None
 1.07A 5yw0A-3tk3A:
undetectable		 5yw0A-3tk3A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umb DEHALOGENASE-LIKE
HYDROLASE

(Ralstonia
solanacearum) 		PF00702
(Hydrolase) 		3 ASP A  10
PHE A  64
ARG A  41
 None
 1.05A 5yw0A-3umbA:
undetectable		 5yw0A-3umbA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v0a NTNH

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		3 ASP B 971
PHE B 571
ARG B 567
 None
 1.15A 5yw0A-3v0aB:
undetectable		 5yw0A-3v0aB:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfz LACTO-N-BIOSE
PHOSPHORYLASE

(Bifidobacterium
longum) 		PF09508
(Lact_bio_phlase)
PF17385
(LBP_M)
PF17386
(LBP_C) 		3 ASP A 182
PHE A 288
ARG A 189
 None
 1.06A 5yw0A-3wfzA:
undetectable		 5yw0A-3wfzA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wkv ION CHANNEL

(Mus musculus) 		PF00520
(Ion_trans) 		3 ASP A 181
PHE A 146
ARG A 204
 None
 1.13A 5yw0A-3wkvA:
undetectable		 5yw0A-3wkvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zus BOTULINUM NEUROTOXIN
TYPE A,
SYNAPTOSOMAL-ASSOCIA
TED PROTEIN 23

(Clostridium
botulinum;
Homo sapiens) 		PF01742
(Peptidase_M27)
PF07952
(Toxin_trans) 		3 ASP A 275
PHE A 282
ARG A 241
 None
 1.10A 5yw0A-3zusA:
undetectable		 5yw0A-3zusA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zus BOTULINUM NEUROTOXIN
TYPE A,
SYNAPTOSOMAL-ASSOCIA
TED PROTEIN 23

(Clostridium
botulinum;
Homo sapiens) 		PF01742
(Peptidase_M27)
PF07952
(Toxin_trans) 		3 ASP A 511
PHE A 423
ARG A 605
 None
 0.75A 5yw0A-3zusA:
undetectable		 5yw0A-3zusA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zxs CRYPTOCHROME B

(Rhodobacter
sphaeroides) 		PF04244
(DPRP) 		3 ASP A  10
PHE A 128
ARG A 307
 DLZ  A1511 (-2.5A)
None
None
 1.15A 5yw0A-3zxsA:
undetectable		 5yw0A-3zxsA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4be9 STEROL ESTERASE

(Ophiostoma
piceae) 		PF00135
(COesterase) 		3 ASP A 424
PHE A 532
ARG A 431
 None
GOL  A1556 ( 3.7A)
None
 0.94A 5yw0A-4be9A:
undetectable		 5yw0A-4be9A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4be9 STEROL ESTERASE

(Ophiostoma
piceae) 		PF00135
(COesterase) 		3 ASP A 424
PHE A 532
ARG A 432
 None
GOL  A1556 ( 3.7A)
None
 1.10A 5yw0A-4be9A:
undetectable		 5yw0A-4be9A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdf MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
C 2

(Mycobacterium
tuberculosis) 		PF01967
(MoaC) 		3 ASP A  64
PHE A  99
ARG A  70
 None
 1.10A 5yw0A-4fdfA:
undetectable		 5yw0A-4fdfA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fj4 UNCHARACTERIZED
PROTEIN

(Halobacterium
salinarum) 		PF07920
(DUF1684) 		3 ASP A 124
PHE A  52
ARG A 132
 None
 0.98A 5yw0A-4fj4A:
undetectable		 5yw0A-4fj4A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fod ALK TYROSINE KINASE
RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 ASP A1270
PHE A1127
ARG A1275
 0UV  A1501 ( 4.2A)
None
None
 1.03A 5yw0A-4fodA:
undetectable		 5yw0A-4fodA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hoz SUCROSE ISOMERASE

(Erwinia
rhapontici) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 ASP A 435
PHE A 263
ARG A 333
 None
 1.16A 5yw0A-4hozA:
undetectable		 5yw0A-4hozA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB

(Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		3 ASP A 240
PHE A 284
ARG A 321
 None
 0.99A 5yw0A-4iglA:
undetectable		 5yw0A-4iglA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k0x BETA-LACTAMASE

(Acinetobacter
baumannii) 		PF00905
(Transpeptidase) 		3 ASP A  96
PHE A 101
ARG A 137
 None
 1.04A 5yw0A-4k0xA:
undetectable		 5yw0A-4k0xA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq7 HYPOTHETICAL PROTEIN

(Bacteroides
uniformis) 		PF11175
(DUF2961) 		3 ASP A 146
PHE A 390
ARG A 318
 None
 1.01A 5yw0A-4kq7A:
undetectable		 5yw0A-4kq7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nxy ACYL-COA SYNTHETASE

(Streptomyces
lividans) 		PF00583
(Acetyltransf_1) 		3 ASP A 106
PHE A  80
ARG A  64
 None
ETF  A 201 (-3.8A)
None
 1.06A 5yw0A-4nxyA:
undetectable		 5yw0A-4nxyA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4per ANGIOGENIN

(Gallus gallus) 		PF00074
(RnaseA) 		3 ASP B  14
PHE B  20
ARG B  33
 None
 0.92A 5yw0A-4perB:
undetectable		 5yw0A-4perB:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rih GLYCOSYL TRANSFERASE
HOMOLOG,GLYCOSYL
TRANSFERASE

(Streptomyces
fradiae;
Streptomyces
cyanogenus) 		PF06722
(DUF1205) 		3 ASP A 137
PHE A  88
ARG A 220
 3R2  A 401 (-3.6A)
None
3R2  A 401 (-3.7A)
 0.94A 5yw0A-4rihA:
undetectable		 5yw0A-4rihA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE

(Staphylococcus
aureus) 		PF00388
(PI-PLC-X) 		3 ASP A  31
PHE A 239
ARG A 166
 INS  A 402 ( 4.3A)
INS  A 402 ( 4.1A)
INS  A 402 (-2.6A)
 1.08A 5yw0A-4rv3A:
undetectable		 5yw0A-4rv3A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w2r ENHANCER OF ZESTE 2
POLYCOMB REPRESSIVE
COMPLEX 2 SUBUNIT

(Anolis
carolinensis) 		no annotation 3 ASP A 480
PHE A 278
ARG A 275
 None
 1.08A 5yw0A-4w2rA:
undetectable		 5yw0A-4w2rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxx DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Homo sapiens) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC)
PF12047
(DNMT1-RFD) 		3 ASP A1067
PHE A1085
ARG A 995
 None
 1.13A 5yw0A-4wxxA:
undetectable		 5yw0A-4wxxA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzb NITROGENASE
MOLYBDENUM-IRON
PROTEIN ALPHA CHAIN

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro) 		3 ASP A 228
PHE A 300
ARG A 359
 None
None
ICS  A1496 (-3.9A)
 1.15A 5yw0A-4wzbA:
undetectable		 5yw0A-4wzbA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ydh FORMIN-LIKE PROTEIN
1

(Homo sapiens) 		PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 ASP A 287
PHE A 342
ARG A 305
 None
 1.06A 5yw0A-4ydhA:
undetectable		 5yw0A-4ydhA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z11 AURONE SYNTHASE

(Coreopsis
grandiflora) 		PF00264
(Tyrosinase)
PF12142
(PPO1_DWL)
PF12143
(PPO1_KFDV) 		3 ASP A 190
PHE A 431
ARG A 496
 None
 1.13A 5yw0A-4z11A:
undetectable		 5yw0A-4z11A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5afu DYNACTIN

(Sus scrofa) 		PF00022
(Actin) 		3 ASP A 162
PHE A 211
ARG A 192
 ADP  A 800 ( 3.2A)
None
None
 0.87A 5yw0A-5afuA:
undetectable		 5yw0A-5afuA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3f PHOSPHORIBULOKINASE/
URIDINE KINASE

(Methanospirillum
hungatei) 		PF00485
(PRK) 		3 ASP A 141
PHE A 178
ARG A 144
 None
 1.00A 5yw0A-5b3fA:
undetectable		 5yw0A-5b3fA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bxg UNCHARACTERIZED
BETA-SANDWICH
PROTEIN

(Clostridioides
difficile) 		no annotation 3 ASP A  70
PHE A 137
ARG A 154
 None
None
EDO  A 203 (-3.7A)
 1.10A 5yw0A-5bxgA:
undetectable		 5yw0A-5bxgA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9e SEPL

(Escherichia
coli) 		PF07201
(HrpJ) 		3 ASP A 272
PHE A 206
ARG A 215
 None
 1.03A 5yw0A-5c9eA:
undetectable		 5yw0A-5c9eA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5exk LIPOYL SYNTHASE

(Mycobacterium
tuberculosis) 		PF04055
(Radical_SAM)
PF16881
(LIAS_N) 		3 ASP A 227
PHE A 271
ARG A 261
 None
 1.11A 5yw0A-5exkA:
undetectable		 5yw0A-5exkA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f75 THIOCYANATE
DEHYDROGENASE

(Thioalkalivibrio
paradoxus) 		no annotation 3 ASP A 230
PHE A 140
ARG A 181
 None
 1.08A 5yw0A-5f75A:
undetectable		 5yw0A-5f75A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gut DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Mus musculus) 		PF00145
(DNA_methylase)
PF01426
(BAH) 		3 ASP A1070
PHE A1088
ARG A 999
 None
 1.10A 5yw0A-5gutA:
undetectable		 5yw0A-5gutA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i2x ADRENOCORTICAL
DYSPLASIA PROTEIN
HOMOLOG

(Homo sapiens) 		PF10341
(TPP1) 		3 ASP A 123
PHE A 171
ARG A 159
 None
 0.86A 5yw0A-5i2xA:
undetectable		 5yw0A-5i2xA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i67 PHOSPHOENOLPYRUVATE
CARBOXYKINASE [GTP]

(Mycobacterium
tuberculosis) 		PF00821
(PEPCK_C)
PF17297
(PEPCK_N) 		3 ASP A 296
PHE A 468
ARG A  81
 MN  A 705 (-3.5A)
None
None
 1.11A 5yw0A-5i67A:
undetectable		 5yw0A-5i67A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5joz NON-REDUCING END
ALPHA-L-ARABINOFURAN
OSIDASE BOGH43B

(Bacteroides
ovatus) 		PF04616
(Glyco_hydro_43) 		3 ASP A 148
PHE A  55
ARG A 290
 None
 1.13A 5yw0A-5jozA:
undetectable		 5yw0A-5jozA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n2g DNA POLYMERASE

(Vaccinia virus) 		no annotation 3 ASP A 984
PHE A 541
ARG A 746
 None
 1.12A 5yw0A-5n2gA:
undetectable		 5yw0A-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n9u DEHYDROASCORBATE
REDUCTASE FAMILY
PROTEIN

(Populus
trichocarpa) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		3 ASP A  72
PHE A 103
ARG A  25
 GSH  A 301 (-1.7A)
None
GSH  A 301 ( 4.7A)
 1.12A 5yw0A-5n9uA:
undetectable		 5yw0A-5n9uA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb CELL DIVISION CYCLE
PROTEIN CDT1

(Saccharomyces
cerevisiae) 		PF16679
(CDT1_C) 		3 ASP 8 369
PHE 8 318
ARG 8 399
 None
 1.03A 5yw0A-5udb8:
7.7		 5yw0A-5udb8:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5utu ADENOSYLHOMOCYSTEINA
SE

(Cryptosporidium
parvum) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		3 ASP A 136
PHE A 357
ARG A 218
 None
SAH  A 502 (-4.8A)
None
 1.16A 5yw0A-5utuA:
undetectable		 5yw0A-5utuA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wkh T-CELL RECEPTOR
ALPHA VARIABLE
30,T-CELL RECEPTOR,
SP3.4 ALPHA CHAIN
D30 TCR BETA CHAIN

(Homo sapiens;
Homo sapiens) 		PF07686
(V-set)
PF09291
(DUF1968)
no annotation 		3 ASP D 128
PHE D 179
ARG E 211
 None
 1.14A 5yw0A-5wkhD:
undetectable		 5yw0A-5wkhD:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbp 3NT OXYGENASE BETA
SUBUNIT

(Diaphorobacter
sp. DS2) 		PF00866
(Ring_hydroxyl_B) 		3 ASP C  14
PHE C 176
ARG C  68
 None
 0.99A 5yw0A-5xbpC:
undetectable		 5yw0A-5xbpC:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnc -

(-) 		no annotation 3 ASP A 158
PHE A 111
ARG A 118
 None
 1.12A 5yw0A-5xncA:
undetectable		 5yw0A-5xncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnp LEUCINE-RICH REPEAT
AND FIBRONECTIN
TYPE-III
DOMAIN-CONTAINING
PROTEIN 5

(Homo sapiens) 		no annotation 3 ASP A 258
PHE A 237
ARG A 256
 None
 1.10A 5yw0A-5xnpA:
undetectable		 5yw0A-5xnpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xpg UNCHARACTERIZED
PROTEIN

(Thermus
thermophilus) 		no annotation 3 ASP A 332
PHE A 647
ARG A 444
 None
C  G  19 ( 4.7A)
G  G  20 ( 4.4A)
 1.11A 5yw0A-5xpgA:
undetectable		 5yw0A-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z5d BETA-XYLOSIDASE

(Geobacillus
thermoleovorans) 		no annotation 3 ASP A 121
PHE A  31
ARG A 269
 GOL  A 602 (-3.2A)
GOL  A 602 (-4.8A)
GOL  A 602 (-2.6A)
 1.12A 5yw0A-5z5dA:
undetectable		 5yw0A-5z5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4v POLYKETIDE SYNTHASE
PKS13

(Mycobacterium
tuberculosis) 		no annotation 3 ASP A1441
PHE A1399
ARG A1376
 ZN  A1502 (-2.1A)
None
None
 1.03A 5yw0A-6c4vA:
undetectable		 5yw0A-6c4vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dd6 PHOTOLYASE PHRB

(Agrobacterium
tumefaciens) 		no annotation 3 ASP A  10
PHE A 132
ARG A 311
 DLZ  A 602 (-3.0A)
None
None
 0.88A 5yw0A-6dd6A:
undetectable		 5yw0A-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eot DIPEPTIDYL PEPTIDASE
8

(Homo sapiens) 		no annotation 3 ASP A 788
PHE A 277
ARG A 794
 None
 1.13A 5yw0A-6eotA:
undetectable		 5yw0A-6eotA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fjy PROTEIN CSUE

(Acinetobacter
baumannii) 		no annotation 3 ASP D 168
PHE D 132
ARG D  51
 None
 1.12A 5yw0A-6fjyD:
undetectable		 5yw0A-6fjyD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fsw RIBOSOME MATURATION
PROTEIN SDO1-LIKE
PROTEIN

(Archaeoglobus
fulgidus) 		no annotation 3 ASP A  73
PHE A  41
ARG A  79
 None
 1.02A 5yw0A-6fswA:
undetectable		 5yw0A-6fswA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
10, MITOCHONDRIAL

(Mus musculus) 		no annotation 3 ASP O  28
PHE O 134
ARG O 104
 None
ADP  O 401 (-3.6A)
ADP  O 401 (-4.5A)
 0.99A 5yw0A-6g2jO:
undetectable		 5yw0A-6g2jO:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gdt -

(-) 		no annotation 3 ASP A 432
PHE A 359
ARG A 356
 None
 1.06A 5yw0A-6gdtA:
undetectable		 5yw0A-6gdtA:
undetectable