SIMILAR PATTERNS OF AMINO ACIDS FOR 5YVN_A_ACTA305

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bue PROTEIN
(IMIPENEM-HYDROLYSIN
G BETA-LACTAMASE)

(Enterobacter
cloacae) 		PF13354
(Beta-lactamase2) 		4 LEU A 169
LYS A  73
LEU A  76
LEU A 139
 None
 1.02A 5yvnA-1bueA:
0.0		 5yvnA-1bueA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c9e PROTOHEME FERROLYASE

(Bacillus
subtilis) 		PF00762
(Ferrochelatase) 		4 LEU A 113
GLN A  63
LEU A  67
LEU A 300
 None
 1.14A 5yvnA-1c9eA:
0.4		 5yvnA-1c9eA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dj3 ADENYLOSUCCINATE
SYNTHETASE

(Triticum
aestivum) 		PF00709
(Adenylsucc_synt) 		4 GLU A 303
LEU A 299
LYS A 359
LEU A 355
 None
 1.15A 5yvnA-1dj3A:
0.0		 5yvnA-1dj3A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e5r PROLINE OXIDASE

(Streptomyces
sp. TH1) 		PF05118
(Asp_Arg_Hydrox)
PF05373
(Pro_3_hydrox_C) 		4 LEU A  20
GLN A 169
LEU A 171
LEU A  78
 None
 1.17A 5yvnA-1e5rA:
undetectable		 5yvnA-1e5rA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g1a DTDP-D-GLUCOSE
4,6-DEHYDRATASE

(Salmonella
enterica) 		PF16363
(GDP_Man_Dehyd) 		4 LEU A 221
GLN A 290
LEU A 216
LEU A 277
 None
 1.08A 5yvnA-1g1aA:
0.7		 5yvnA-1g1aA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g3m ESTROGEN
SULFOTRANSFERASE

(Homo sapiens) 		PF00685
(Sulfotransfer_1) 		4 GLU A 202
LEU A 195
LEU A 188
LEU A 206
 None
 1.16A 5yvnA-1g3mA:
1.5		 5yvnA-1g3mA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gjj LAP2

(Homo sapiens) 		PF03020
(LEM)
PF08198
(Thymopoietin) 		4 GLU A  19
LEU A  11
LEU A  45
LEU A 146
 None
 0.97A 5yvnA-1gjjA:
undetectable		 5yvnA-1gjjA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gjj LAP2

(Homo sapiens) 		PF03020
(LEM)
PF08198
(Thymopoietin) 		4 GLU A  19
LEU A 115
LEU A  45
LEU A 146
 None
 0.93A 5yvnA-1gjjA:
undetectable		 5yvnA-1gjjA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkw DIAMINOPIMELATE
DECARBOXYLASE

(Mycobacterium
tuberculosis) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 GLU A 141
LEU A 145
GLN A 156
LEU A 113
 None
 1.20A 5yvnA-1hkwA:
undetectable		 5yvnA-1hkwA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ksh ARF-LIKE PROTEIN 2

(Mus musculus) 		PF00025
(Arf) 		4 LEU A 110
GLN A 107
LEU A 142
LEU A 144
 None
 1.16A 5yvnA-1kshA:
undetectable		 5yvnA-1kshA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n4k INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 1

(Mus musculus) 		PF01365
(RYDR_ITPR)
PF02815
(MIR) 		4 LEU A 509
GLN A 513
LEU A 308
LEU A 281
 None
 1.19A 5yvnA-1n4kA:
5.8		 5yvnA-1n4kA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n9b BETA-LACTAMASE SHV-2

(Klebsiella
pneumoniae) 		PF13354
(Beta-lactamase2) 		4 LEU A 169
LYS A  73
LEU A  76
LEU A 139
 None
 1.00A 5yvnA-1n9bA:
undetectable		 5yvnA-1n9bA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oaa SEPIAPTERIN
REDUCTASE

(Mus musculus) 		PF00106
(adh_short) 		4 LEU A 223
GLN A 207
LEU A 209
LEU A 105
 None
OAA  A   1 ( 3.6A)
None
OAA  A   1 (-4.0A)
 1.14A 5yvnA-1oaaA:
undetectable		 5yvnA-1oaaA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pz1 GENERAL STRESS
PROTEIN 69

(Bacillus
subtilis) 		PF00248
(Aldo_ket_red) 		4 GLU A 108
LEU A 111
LYS A 148
LEU A 143
 None
 1.10A 5yvnA-1pz1A:
undetectable		 5yvnA-1pz1A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbg PYRUVATE,ORTHOPHOSPH
ATE DIKINASE

(Zea mays) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		4 GLU A  78
LYS A 204
LEU A 207
LEU A  94
 None
 1.12A 5yvnA-1vbgA:
undetectable		 5yvnA-1vbgA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wl1 OCTOPRENYL-DIPHOSPHA
TE SYNTHASE

(Thermotoga
maritima) 		PF00348
(polyprenyl_synt) 		4 LEU A 173
GLN A 176
LEU A 181
LEU A 128
 None
 0.97A 5yvnA-1wl1A:
2.2		 5yvnA-1wl1A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y6d PHOSPHORELAY PROTEIN
LUXU

(Vibrio harveyi) 		PF01627
(Hpt) 		4 GLU A  55
LEU A  60
LEU A 102
LEU A  31
 None
 1.13A 5yvnA-1y6dA:
2.1		 5yvnA-1y6dA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zg4 BETA-LACTAMASE TEM

(Escherichia
coli) 		PF13354
(Beta-lactamase2) 		4 LEU A 169
LYS A  73
LEU A  76
LEU A 139
 None
 1.02A 5yvnA-1zg4A:
undetectable		 5yvnA-1zg4A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2atc ASPARTATE
CARBAMOYLTRANSFERASE
, CATALYTIC CHAIN

(Escherichia
coli) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 LEU A  30
GLN A 292
LEU A  39
LEU A  38
 None
 1.19A 5yvnA-2atcA:
undetectable		 5yvnA-2atcA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c8j FERROCHELATASE 1

(Bacillus
anthracis) 		PF00762
(Ferrochelatase) 		4 LEU A 112
GLN A  62
LEU A  66
LEU A 299
 None
 1.16A 5yvnA-2c8jA:
undetectable		 5yvnA-2c8jA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e80 CYTOCHROME C-552

(Wolinella
succinogenes) 		PF02335
(Cytochrom_C552) 		4 GLU A 205
LYS A 196
LEU A 190
LEU A 209
 None
 1.18A 5yvnA-2e80A:
undetectable		 5yvnA-2e80A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h21 RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E

(Pisum sativum) 		PF00856
(SET)
PF09273
(Rubis-subs-bind) 		4 GLU A 187
LYS A 123
LEU A 122
LEU A 191
 None
 0.82A 5yvnA-2h21A:
undetectable		 5yvnA-2h21A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h7v PROTEIN KINASE YPKA

(Yersinia
pseudotuberculosis) 		PF09632
(Rac1) 		4 LEU C 550
GLN C 607
LEU C 608
LEU C 562
 None
 1.13A 5yvnA-2h7vC:
3.6		 5yvnA-2h7vC:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2is7 ALDOSE REDUCTASE

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		4 LEU A  62
GLN A  59
LEU A  99
LEU A 101
 None
 1.05A 5yvnA-2is7A:
undetectable		 5yvnA-2is7A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2je1 ACIDIC LEUCINE-RICH
NUCLEAR
PHOSPHOPROTEIN 32
FAMILY MEMBER A

(Homo sapiens) 		PF14580
(LRR_9) 		4 LEU A 142
GLN A 141
LEU A 112
LEU A 109
 None
 1.18A 5yvnA-2je1A:
undetectable		 5yvnA-2je1A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l29 INSULIN-LIKE GROWTH
FACTOR 2 RECEPTOR
VARIANT

(Homo sapiens) 		PF00878
(CIMR) 		4 LEU A1526
GLN A1517
LEU A1581
LEU A1529
 None
 1.01A 5yvnA-2l29A:
undetectable		 5yvnA-2l29A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lm2 NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2

(Homo sapiens) 		PF02932
(Neur_chan_memb) 		4 GLU A   5
LEU A   8
GLN A 131
LEU A 133
 None
 1.04A 5yvnA-2lm2A:
3.7		 5yvnA-2lm2A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8p 14-3-3 DOMAIN
CONTAINING PROTEIN

(Cryptosporidium
parvum) 		PF00244
(14-3-3) 		4 GLU A  52
LEU A  37
GLN A  14
LEU A  12
 None
 1.10A 5yvnA-2o8pA:
2.7		 5yvnA-2o8pA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pla GLYCEROL-3-PHOSPHATE
DEHYDROGENASE 1-LIKE
PROTEIN

(Homo sapiens) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		4 GLU A 181
LEU A 178
LYS A  33
LEU A  31
 None
 1.18A 5yvnA-2plaA:
undetectable		 5yvnA-2plaA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qtz METHIONINE SYNTHASE
REDUCTASE

(Homo sapiens) 		PF00175
(NAD_binding_1)
PF00667
(FAD_binding_1) 		4 LEU A 254
LYS A 341
LEU A 343
LEU A 442
 CSO  A 340 ( 4.8A)
CSO  A 340 ( 3.2A)
None
None
 1.18A 5yvnA-2qtzA:
undetectable		 5yvnA-2qtzA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qve TYROSINE AMINOMUTASE

(Streptomyces
globisporus) 		PF00221
(Lyase_aromatic) 		4 LEU A 459
GLN A 224
LEU A 222
LEU A 324
 None
 1.10A 5yvnA-2qveA:
1.7		 5yvnA-2qveA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vf8 EXCINUCLEASE ABC
SUBUNIT A

(Deinococcus
radiodurans) 		PF00005
(ABC_tran) 		4 LEU A  97
GLN A 393
LEU A 394
LEU A 427
 None
 1.21A 5yvnA-2vf8A:
undetectable		 5yvnA-2vf8A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vhd CYTOCHROME C551
PEROXIDASE

(Pseudomonas
aeruginosa) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		4 LEU A 181
GLN A 185
LEU A 296
LEU A 299
 None
 1.05A 5yvnA-2vhdA:
undetectable		 5yvnA-2vhdA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3x CALE7

(Micromonospora
echinospora) 		PF13279
(4HBT_2) 		4 GLU A  92
GLN A 112
LYS A  62
LEU A  61
 None
None
None
JEF  A1147 (-4.1A)
 1.07A 5yvnA-2w3xA:
undetectable		 5yvnA-2w3xA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbe BIPOLAR KINESIN
KRP-130

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		4 GLU C 152
LYS C 165
LEU C 154
LEU C 149
 None
 1.01A 5yvnA-2wbeC:
undetectable		 5yvnA-2wbeC:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ww2 ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		PF07971
(Glyco_hydro_92) 		4 GLU A 592
LYS A 634
LEU A 635
LEU A 596
 None
 1.12A 5yvnA-2ww2A:
undetectable		 5yvnA-2ww2A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xva TELLURITE RESISTANCE
PROTEIN TEHB

(Escherichia
coli) 		PF03848
(TehB) 		4 GLU A  21
LYS A 167
LEU A 193
LEU A 131
 None
 0.87A 5yvnA-2xvaA:
undetectable		 5yvnA-2xvaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a14 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE

(Thermotoga
maritima) 		PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C) 		4 LEU A 120
LYS A 128
LEU A 131
LEU A 138
 None
 0.97A 5yvnA-3a14A:
undetectable		 5yvnA-3a14A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cos ALCOHOL
DEHYDROGENASE 4

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLU A 313
LEU A 314
LEU A 307
LEU A 285
 None
 1.16A 5yvnA-3cosA:
undetectable		 5yvnA-3cosA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwz BETA-LACTAMASE

(Mycobacterium
tuberculosis) 		PF13354
(Beta-lactamase2) 		4 LEU A 185
LYS A  87
LEU A  90
LEU A 151
 None
DWZ  A 400 (-2.6A)
None
None
 1.11A 5yvnA-3dwzA:
undetectable		 5yvnA-3dwzA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eoq PUTATIVE ZINC
PROTEASE

(Thermus
thermophilus) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 GLU A 227
LEU A 402
LYS A 307
LEU A 311
 None
 1.00A 5yvnA-3eoqA:
undetectable		 5yvnA-3eoqA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3esl CHECKPOINT
SERINE/THREONINE-PRO
TEIN KINASE BUB1

(Saccharomyces
cerevisiae) 		PF08311
(Mad3_BUB1_I) 		4 GLU A 188
LEU A 191
LYS A 163
LEU A 166
 None
 1.13A 5yvnA-3eslA:
undetectable		 5yvnA-3eslA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3exc UNCHARACTERIZED
PROTEIN

(Sulfolobus
solfataricus) 		PF09827
(CRISPR_Cas2) 		4 GLU X  36
LYS X   2
LEU X  67
LEU X   4
 None
 1.18A 5yvnA-3excX:
undetectable		 5yvnA-3excX:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fvb BACTERIOFERRITIN

(Brucella
abortus) 		PF00210
(Ferritin) 		4 LEU A  40
GLN A 137
LEU A 138
LEU A 141
 None
 1.14A 5yvnA-3fvbA:
undetectable		 5yvnA-3fvbA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g64 PUTATIVE ENOYL-COA
HYDRATASE

(Streptomyces
coelicolor) 		PF00378
(ECH_1) 		4 LEU A 251
GLN A 248
LEU A 243
LEU A 228
 None
 1.11A 5yvnA-3g64A:
undetectable		 5yvnA-3g64A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN

(Pseudomonas
protegens) 		PF13407
(Peripla_BP_4) 		4 LEU A 334
GLN A 338
LEU A 376
LEU A 373
 None
 1.17A 5yvnA-3h75A:
undetectable		 5yvnA-3h75A:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hq9 CYTOCHROME C551
PEROXIDASE

(Geobacter
sulfurreducens) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		4 LEU A 203
GLN A 207
LEU A 318
LEU A 321
 None
 1.01A 5yvnA-3hq9A:
undetectable		 5yvnA-3hq9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ig3 PLXNA3 PROTEIN

(Mus musculus) 		PF08337
(Plexin_cytopl) 		4 GLU A1466
LYS A1651
LEU A1656
LEU A1659
 None
 1.19A 5yvnA-3ig3A:
undetectable		 5yvnA-3ig3A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jbz SERINE/THREONINE-PRO
TEIN KINASE MTOR

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08771
(FRB_dom) 		4 GLN A2524
LYS A2507
LEU A2508
LEU A2407
 None
 1.11A 5yvnA-3jbzA:
4.8		 5yvnA-3jbzA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lf2 SHORT CHAIN
OXIDOREDUCTASE
Q9HYA2

(Pseudomonas
aeruginosa) 		PF13561
(adh_short_C2) 		4 GLU A 153
LEU A 148
LEU A 261
LEU A 191
 None
CL  A 302 (-4.9A)
None
None
 1.07A 5yvnA-3lf2A:
undetectable		 5yvnA-3lf2A:
22.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3lfl GLUTATHIONE
S-TRANSFERASE
OMEGA-1

(Homo sapiens) 		PF13417
(GST_N_3)
PF14497
(GST_C_3) 		4 GLU A  91
LEU A 103
GLN A 113
LYS A 114
 None
 0.89A 5yvnA-3lflA:
36.7		 5yvnA-3lflA:
99.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3lfl GLUTATHIONE
S-TRANSFERASE
OMEGA-1

(Homo sapiens) 		PF13417
(GST_N_3)
PF14497
(GST_C_3) 		5 LEU A 103
GLN A 113
LYS A 114
LEU A 117
LEU A 175
 None
 0.43A 5yvnA-3lflA:
36.7		 5yvnA-3lflA:
99.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3luf TWO-COMPONENT SYSTEM
RESPONSE
REGULATOR/GGDEF
DOMAIN PROTEIN

(Aeromonas
salmonicida) 		PF00072
(Response_reg) 		4 GLU A   9
LYS A 101
LEU A 107
LEU A  18
 MG  A 301 ( 4.3A)
MG  A 301 ( 4.3A)
None
None
 1.18A 5yvnA-3lufA:
2.8		 5yvnA-3lufA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o14 ANTI-ECFSIGMA
FACTOR, CHRR

(Marinobacter
hydrocarbonoclasticus) 		PF12973
(Cupin_7) 		4 GLU A 124
LEU A 127
LYS A 206
LEU A 171
 None
 1.03A 5yvnA-3o14A:
undetectable		 5yvnA-3o14A:
22.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3q19 GLUTATHIONE
S-TRANSFERASE
OMEGA-2

(Homo sapiens) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		5 GLU A  91
GLN A 113
LYS A 114
LEU A 117
LEU A 177
 None
 0.49A 5yvnA-3q19A:
32.9		 5yvnA-3q19A:
65.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q9t CHOLINE
DEHYDROGENASE AND
RELATED
FLAVOPROTEINS

(Aspergillus
oryzae) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 GLU A 120
LYS A 532
LEU A 533
LEU A 520
 None
 1.11A 5yvnA-3q9tA:
undetectable		 5yvnA-3q9tA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qld MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLU A  46
LYS A  28
LEU A  12
LEU A  10
 None
 1.21A 5yvnA-3qldA:
undetectable		 5yvnA-3qldA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rip GAMMA-TUBULIN
COMPLEX COMPONENT 4

(Homo sapiens) 		PF04130
(Spc97_Spc98) 		4 LEU A 462
GLN A 353
LEU A 351
LEU A 354
 None
 1.15A 5yvnA-3ripA:
2.4		 5yvnA-3ripA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5k FALCILYSIN

(Plasmodium
falciparum) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		4 LEU A 852
GLN A 901
LEU A 904
LEU A 912
 None
 1.17A 5yvnA-3s5kA:
undetectable		 5yvnA-3s5kA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t24 PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 GLN A 131
LYS A 151
LEU A 150
LEU A 111
 None
 0.87A 5yvnA-3t24A:
undetectable		 5yvnA-3t24A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tjz ADP-RIBOSYLATION
FACTOR 1

(Saccharomyces
cerevisiae) 		PF00025
(Arf) 		4 LEU A 111
GLN A 108
LEU A 143
LEU A 145
 None
 1.14A 5yvnA-3tjzA:
undetectable		 5yvnA-3tjzA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdj ENCA BETA-LACTAMASE

(synthetic
construct) 		PF13354
(Beta-lactamase2) 		4 LEU A 169
LYS A  73
LEU A  76
LEU A 139
 None
 1.01A 5yvnA-3zdjA:
undetectable		 5yvnA-3zdjA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c6y BETA-LACTAMASE

(synthetic
construct) 		PF13354
(Beta-lactamase2) 		4 LEU A 169
LYS A  73
LEU A  76
LEU A 139
 None
PEG  A 307 ( 3.6A)
None
None
 1.01A 5yvnA-4c6yA:
undetectable		 5yvnA-4c6yA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvq GLUTAMATE-PYRUVATE
AMINOTRANSFERASE
ALAA

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 GLU A  29
LYS A  37
LEU A 362
LEU A 356
 None
 0.99A 5yvnA-4cvqA:
undetectable		 5yvnA-4cvqA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dxb MALTOSE-BINDING
PERIPLASMIC PROTEIN,
BETA-LACTAMASE TEM
CHIMERA

(Escherichia
coli) 		PF01547
(SBP_bac_1)
PF13354
(Beta-lactamase2) 		4 LEU A 525
LYS A 429
LEU A 432
LEU A 495
 None
 0.98A 5yvnA-4dxbA:
undetectable		 5yvnA-4dxbA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ev4 CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1

(Serratia
fonticola) 		PF13354
(Beta-lactamase2) 		4 LEU A 169
LYS A  73
LEU A  76
LEU A 139
 None
MER  A 401 ( 4.4A)
None
None
 1.08A 5yvnA-4ev4A:
undetectable		 5yvnA-4ev4A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0x MALONYL-COA
DECARBOXYLASE,
MITOCHONDRIAL

(Homo sapiens) 		PF05292
(MCD)
PF17408
(MCD_N) 		4 GLU A 302
LEU A 307
LEU A 250
LEU A 195
 None
 1.17A 5yvnA-4f0xA:
3.5		 5yvnA-4f0xA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fym OROTATE
PHOSPHORIBOSYLTRANSF
ERASE

(Plasmodium
falciparum) 		PF00156
(Pribosyltran) 		4 LEU A 271
LYS A  72
LEU A  76
LEU A  81
 None
 1.15A 5yvnA-4fymA:
undetectable		 5yvnA-4fymA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lfy DIHYDROOROTASE

(Burkholderia
cenocepacia) 		PF01979
(Amidohydro_1) 		4 GLU A 294
LEU A 295
LEU A 290
LEU A 339
 None
 1.17A 5yvnA-4lfyA:
undetectable		 5yvnA-4lfyA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lq8 SCA-FAMILY PROTEIN

(Rickettsia
rickettsii) 		PF12574
(120_Rick_ant) 		4 GLN A  97
LYS A  98
LEU A 101
LEU A 348
 None
 1.20A 5yvnA-4lq8A:
undetectable		 5yvnA-4lq8A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mfi SN-GLYCEROL-3-PHOSPH
ATE ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN USPB

(Mycobacterium
tuberculosis) 		PF13416
(SBP_bac_8) 		4 LEU A 156
GLN A 374
LEU A 372
LEU A 346
 None
 1.05A 5yvnA-4mfiA:
undetectable		 5yvnA-4mfiA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mmo SSO-CP2
METALLO-CARBOXYPETID
ASE

(Sulfolobus
solfataricus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 GLU A  46
LYS A 154
LEU A 155
LEU A 132
 None
 1.16A 5yvnA-4mmoA:
undetectable		 5yvnA-4mmoA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nlm LMO1340 PROTEIN

(Listeria
monocytogenes) 		no annotation 4 GLU A 201
LEU A 202
LYS A 238
LEU A 244
 None
 1.19A 5yvnA-4nlmA:
undetectable		 5yvnA-4nlmA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4piv FATTY ACID SYNTHASE

(Homo sapiens) 		PF08242
(Methyltransf_12)
PF08659
(KR) 		4 GLU A1137
LEU A1134
LEU A1215
LEU A1353
 None
 1.19A 5yvnA-4pivA:
undetectable		 5yvnA-4pivA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3

(Thermobaculum
terrenum) 		PF00271
(Helicase_C) 		4 GLU A 641
LEU A 628
LEU A 645
LEU A 670
 None
 1.02A 5yvnA-4q2cA:
undetectable		 5yvnA-4q2cA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1

(Homo sapiens;
synthetic
construct) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 LEU A3399
GLN A3402
LEU A3406
LEU A3524
 None
 1.14A 5yvnA-4rh7A:
undetectable		 5yvnA-4rh7A:
5.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aqa OFF7_DB04V3

(synthetic
construct) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13354
(Beta-lactamase2) 		4 LEU A 299
LYS A 203
LEU A 206
LEU A 269
 None
 0.98A 5yvnA-5aqaA:
undetectable		 5yvnA-5aqaA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7i CRISPR-ASSOCIATED
NUCLEASE/HELICASE
CAS3 SUBTYPE
I-F/YPEST

(Pseudomonas
aeruginosa) 		no annotation 4 LEU A 374
GLN A 538
LEU A 527
LEU A 523
 None
 1.05A 5yvnA-5b7iA:
undetectable		 5yvnA-5b7iA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dbk TRANSCRIPTIONAL
REGULATOR/TPR DOMAIN
PROTEIN

(Bacillus
thuringiensis) 		PF13424
(TPR_12) 		4 GLU A 326
LEU A 330
LYS A 290
LEU A 294
 None
 1.09A 5yvnA-5dbkA:
3.8		 5yvnA-5dbkA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eoe BETA-LACTAMASE

(Pseudomonas
aeruginosa) 		PF13354
(Beta-lactamase2) 		4 LEU A 162
LYS A  65
LEU A  68
LEU A 132
 None
CIT  A 303 (-3.6A)
None
None
 1.10A 5yvnA-5eoeA:
undetectable		 5yvnA-5eoeA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey6 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF2

(Populus
trichocarpa) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 GLU A 140
LEU A 188
LEU A 121
LEU A 117
 None
 0.98A 5yvnA-5ey6A:
20.3		 5yvnA-5ey6A:
26.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5htf FOLDASE PROTEIN PRSA
1

(Listeria
monocytogenes) 		PF13616
(Rotamase_3) 		4 GLU A 107
GLN A  55
LYS A  59
LEU A  62
 None
 1.19A 5yvnA-5htfA:
undetectable		 5yvnA-5htfA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iuf BIFUNCTIONAL
OLIGORIBONUCLEASE
AND PAP PHOSPHATASE
NRNA

(Bacillus
subtilis) 		PF01368
(DHH)
PF02272
(DHHA1) 		4 LEU A 186
GLN A 189
LEU A  57
LEU A  60
 None
 1.18A 5yvnA-5iufA:
undetectable		 5yvnA-5iufA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l0j VINCULIN

(Homo sapiens) 		PF01044
(Vinculin) 		4 GLN A 994
LYS A 996
LEU A 995
LEU A1030
 None
 1.17A 5yvnA-5l0jA:
undetectable		 5yvnA-5l0jA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ll7 BETA-LACTAMASE

(Escherichia
coli) 		no annotation 4 LEU A 169
LYS A  73
LEU A  76
LEU A 139
 None
6YV  A 301 ( 3.8A)
None
None
 0.98A 5yvnA-5ll7A:
undetectable		 5yvnA-5ll7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5loh SERINE/THREONINE-PRO
TEIN KINASE
GREATWALL,SERINE/THR
EONINE-PROTEIN
KINASE GREATWALL

(Homo sapiens) 		PF00069
(Pkinase) 		4 GLU A 130
LEU A 834
LEU A 804
LEU A 772
 None
 1.00A 5yvnA-5lohA:
undetectable		 5yvnA-5lohA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ods CLATHRIN HEAVY CHAIN
1

(Mus musculus) 		no annotation 4 LEU A 148
GLN A 182
LEU A 183
LEU A 166
 None
 1.17A 5yvnA-5odsA:
undetectable		 5yvnA-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5txk UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE
35,UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 35

(Homo sapiens) 		no annotation 4 LEU A 472
GLN A 478
LEU A 480
LEU A 532
 None
 1.13A 5yvnA-5txkA:
undetectable		 5yvnA-5txkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uf8 POTENTIAL
ADP-RIBOSYLATION
FACTOR

(Candida
albicans) 		PF00025
(Arf) 		4 LEU A 111
GLN A 108
LEU A 143
LEU A 145
 None
 1.16A 5yvnA-5uf8A:
undetectable		 5yvnA-5uf8A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhe DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA'

(Mycobacterium
tuberculosis) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 GLU D 675
GLN D 639
LEU D 637
LEU D 640
 None
 1.04A 5yvnA-5uheD:
2.5		 5yvnA-5uheD:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uu1 SERINE/THREONINE-PRO
TEIN KINASE VRK2

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 248
LYS A 264
LEU A 268
LEU A 292
 None
 1.11A 5yvnA-5uu1A:
undetectable		 5yvnA-5uu1A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wbt INSULIN

(Homo sapiens) 		no annotation 4 LEU A   6
LYS A   1
LEU A  49
LEU A  52
 None
 1.03A 5yvnA-5wbtA:
undetectable		 5yvnA-5wbtA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xuk HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE

(Helicobacter
pylori) 		no annotation 4 GLU A  32
LEU A  28
LYS A  50
LEU A  49
 None
 1.10A 5yvnA-5xukA:
undetectable		 5yvnA-5xukA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y7o UGGT

(Thermomyces
dupontii) 		PF06427
(UDP-g_GGTase) 		4 LEU A 719
GLN A 767
LEU A 748
LEU A 751
 None
 1.18A 5yvnA-5y7oA:
undetectable		 5yvnA-5y7oA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z7q FLAGELLIN

(Bacillus cereus) 		no annotation 4 GLU A 200
LEU A 169
LEU A 136
LEU A  80
 None
 1.20A 5yvnA-5z7qA:
2.4		 5yvnA-5z7qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli) 		no annotation 4 LEU A 888
GLN A 112
LEU A 115
LEU A 960
 None
 1.06A 5yvnA-6bogA:
undetectable		 5yvnA-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6chj DIACYLGLYCEROL
O-ACYLTRANSFERASE

(Marinobacter
hydrocarbonoclasticus) 		no annotation 4 LEU A  14
GLN A  19
LEU A 408
LEU A 363
 None
 1.10A 5yvnA-6chjA:
undetectable		 5yvnA-6chjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cri -

(-) 		no annotation 4 GLU M 100
LEU M  16
LYS M  12
LEU M  11
 None
 1.04A 5yvnA-6criM:
undetectable		 5yvnA-6criM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		no annotation
no annotation 		4 GLU A 987
LYS A 369
LEU A 368
LEU D  53
 None
 1.20A 5yvnA-6eojA:
undetectable		 5yvnA-6eojA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eq8 PERIPLASMIC
ALPHA-GALACTOSIDE-BI
NDING PROTEIN

(Agrobacterium
tumefaciens) 		no annotation 4 GLU D 647
LEU D 304
LEU D  35
LEU D  71
 None
 1.15A 5yvnA-6eq8D:
undetectable		 5yvnA-6eq8D:
undetectable