SIMILAR PATTERNS OF AMINO ACIDS FOR 5YOD_D_BEZD201_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bh6 | SUBTILISIN DY (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 4 | ALA A 134SER A 132GLY A 131TYR A 171 | NoneNone1BH A 300 ( 4.8A)None | 1.21A | 5yodD-1bh6A:undetectable | 5yodD-1bh6A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c0n | PROTEIN (CSDBPROTEIN) (Escherichiacoli) |
PF00266(Aminotran_5) | 4 | HIS A 59ALA A 53SER A 62GLY A 57 | None | 1.11A | 5yodD-1c0nA:undetectable | 5yodD-1c0nA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c3l | SUBTILISIN-CARLSBERG (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 4 | ALA A 134SER A 132GLY A 131TYR A 171 | None | 1.19A | 5yodD-1c3lA:undetectable | 5yodD-1c3lA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1coy | CHOLESTEROL OXIDASE (Brevibacteriumsterolicum) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | ALA A 223SER A 211GLY A 212TYR A 195 | None | 1.19A | 5yodD-1coyA:undetectable | 5yodD-1coyA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gk2 | HISTIDINEAMMONIA-LYASE (Pseudomonasputida) |
PF00221(Lyase_aromatic) | 4 | HIS A 330ALA A 335SER A 418GLY A 141 | None | 1.28A | 5yodD-1gk2A:undetectable | 5yodD-1gk2A:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gns | SUBTILISIN BPN' (Bacillusamyloliquefaciens) |
PF00082(Peptidase_S8) | 4 | ALA A 134SER A 132GLY A 131TYR A 171 | None | 1.19A | 5yodD-1gnsA:undetectable | 5yodD-1gnsA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gpl | RP2 LIPASE (Cavia porcellus) |
PF00151(Lipase)PF01477(PLAT) | 4 | HIS A 263ALA A 178SER A 152GLY A 76 | None | 1.25A | 5yodD-1gplA:undetectable | 5yodD-1gplA:18.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h71 | SERRALYSIN (Pseudomonas sp.'TAC II 18') |
PF00413(Peptidase_M10)PF08548(Peptidase_M10_C) | 4 | HIS P 23ALA P 198SER P 30TYR P 204 | None | 1.24A | 5yodD-1h71P:undetectable | 5yodD-1h71P:17.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hpg | GLUTAMIC ACIDSPECIFIC PROTEASE (Streptomycesgriseus) |
no annotation | 4 | ALA A 30SER A 43GLY A 140TYR A 120 | None | 1.07A | 5yodD-1hpgA:10.1 | 5yodD-1hpgA:24.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmo | HEPARIN COFACTOR II (Homo sapiens) |
PF00079(Serpin) | 4 | HIS A 159SER A 147GLY A 144TYR A 225 | None | 1.06A | 5yodD-1jmoA:undetectable | 5yodD-1jmoA:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1js6 | DOPA DECARBOXYLASE (Sus scrofa) |
PF00282(Pyridoxal_deC) | 4 | HIS A 302ALA A 148SER A 312GLY A 146 | PLP A 601 (-4.2A)PLP A 601 (-3.4A)NoneNone | 1.26A | 5yodD-1js6A:undetectable | 5yodD-1js6A:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1koa | TWITCHIN (Caenorhabditiselegans) |
PF00069(Pkinase)PF07679(I-set) | 4 | HIS A6089ALA A6264SER A6292TYR A6118 | None | 1.23A | 5yodD-1koaA:undetectable | 5yodD-1koaA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhb | HALOPEROXIDASE (Corallinaofficinalis) |
PF01569(PAP2) | 4 | HIS A 551ALA A 486SER A 483GLY A 482 | PO4 A3000 ( 4.0A)NonePO4 A3000 ( 3.0A)None | 1.24A | 5yodD-1qhbA:undetectable | 5yodD-1qhbA:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qv9 | F420-DEPENDENTMETHYLENETETRAHYDROMETHANOPTERINDEHYDROGENASE (Methanopyruskandleri) |
PF01993(MTD) | 4 | ALA A 214SER A 217GLY A 126TYR A 140 | None | 1.22A | 5yodD-1qv9A:undetectable | 5yodD-1qv9A:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ry2 | ACETYL-COENZYME ASYNTHETASE 1 (Saccharomycescerevisiae) |
PF00501(AMP-binding)PF13193(AMP-binding_C)PF16177(ACAS_N) | 4 | ALA A 193SER A 237GLY A 235TYR A 319 | None | 1.26A | 5yodD-1ry2A:undetectable | 5yodD-1ry2A:15.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t0a | 2C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Shewanellaoneidensis) |
PF02542(YgbB) | 4 | HIS A 44ALA A 73SER A 37GLY A 39 | ZN A 661 (-3.1A)NoneNoneNone | 1.16A | 5yodD-1t0aA:undetectable | 5yodD-1t0aA:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vjv | UBIQUITINCARBOXYL-TERMINALHYDROLASE 6 (Saccharomycescerevisiae) |
PF00443(UCH) | 4 | HIS A 438ALA A 441SER A 445GLY A 446 | None | 1.13A | 5yodD-1vjvA:undetectable | 5yodD-1vjvA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wr1 | UBIQUITIN-LIKEPROTEIN DSK2 (Saccharomycescerevisiae) |
PF00627(UBA) | 4 | ALA B 353SER B 357GLY B 358TYR B 332 | None | 1.19A | 5yodD-1wr1B:undetectable | 5yodD-1wr1B:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wr1 | UBIQUITIN-LIKEPROTEIN DSK2 (Saccharomycescerevisiae) |
PF00627(UBA) | 4 | ALA B 364SER B 357GLY B 358TYR B 332 | None | 1.19A | 5yodD-1wr1B:undetectable | 5yodD-1wr1B:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x42 | HYPOTHETICAL PROTEINPH0459 (Pyrococcushorikoshii) |
PF13419(HAD_2) | 4 | HIS A 117ALA A 164SER A 144GLY A 119 | None | 1.18A | 5yodD-1x42A:undetectable | 5yodD-1x42A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ahr | PUTATIVE PYRROLINECARBOXYLATEREDUCTASE (Streptococcuspyogenes) |
PF03807(F420_oxidored)PF14748(P5CR_dimer) | 4 | HIS A 51ALA A 48SER A 29GLY A 30 | NAP A1500 (-4.0A)NoneNoneNAP A1500 (-4.2A) | 1.06A | 5yodD-2ahrA:undetectable | 5yodD-2ahrA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bwb | UBIQUITIN-LIKEPROTEIN DSK2 (Saccharomycescerevisiae) |
PF00627(UBA) | 4 | ALA A 353SER A 357GLY A 358TYR A 332 | None | 1.23A | 5yodD-2bwbA:undetectable | 5yodD-2bwbA:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bwb | UBIQUITIN-LIKEPROTEIN DSK2 (Saccharomycescerevisiae) |
PF00627(UBA) | 4 | ALA A 364SER A 357GLY A 358TYR A 332 | None | 1.27A | 5yodD-2bwbA:undetectable | 5yodD-2bwbA:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cvz | 3-HYDROXYISOBUTYRATEDEHYDROGENASE (Thermusthermophilus) |
PF03446(NAD_binding_2)PF14833(NAD_binding_11) | 4 | HIS A 39ALA A 47SER A 45GLY A 44 | None | 1.22A | 5yodD-2cvzA:undetectable | 5yodD-2cvzA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ea3 | CHYMOTRYPSIN (Cellulomonasbogoriensis) |
PF00089(Trypsin) | 4 | ALA A 8SER A 18GLY A 98TYR A 75 | None | 1.15A | 5yodD-2ea3A:6.6 | 5yodD-2ea3A:22.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fp7 | GENOME POLYPROTEIN (West Nile virus) |
PF00949(Peptidase_S7) | 4 | HIS B 51SER B 135GLY B 151TYR B 161 | None | 0.37A | 5yodD-2fp7B:28.0 | 5yodD-2fp7B:62.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gzl | 2-C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Escherichiacoli) |
PF02542(YgbB) | 4 | HIS A 42ALA A 71SER A 35GLY A 37 | ZN A 900 (-3.1A)2AA A 901 (-3.6A)2AA A 901 (-3.7A)None | 1.23A | 5yodD-2gzlA:undetectable | 5yodD-2gzlA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i3o | GAMMA-GLUTAMYLTRANSFERASE RELATEDPROTEIN (Thermoplasmaacidophilum) |
PF01019(G_glu_transpept) | 4 | ALA A 113SER A 115GLY A 77TYR A 231 | None | 1.18A | 5yodD-2i3oA:undetectable | 5yodD-2i3oA:17.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2okj | GLUTAMATEDECARBOXYLASE 1 (Homo sapiens) |
PF00282(Pyridoxal_deC) | 4 | HIS A 404ALA A 375SER A 414GLY A 251 | LLP A 405 ( 4.2A)LLP A 405 ( 3.6A)NoneLLP A 405 ( 3.3A) | 1.22A | 5yodD-2okjA:undetectable | 5yodD-2okjA:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2okk | GLUTAMATEDECARBOXYLASE 2 (Homo sapiens) |
PF00282(Pyridoxal_deC) | 4 | HIS A 395ALA A 366SER A 405GLY A 242 | LLP A 396 ( 4.1A)LLP A 396 ( 3.5A)LLP A 396 ( 4.9A)LLP A 396 ( 3.4A) | 1.19A | 5yodD-2okkA:undetectable | 5yodD-2okkA:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oua | SERINE PROTEASE (Nocardiopsisalba) |
PF00089(Trypsin) | 4 | ALA A 34SER A 43GLY A 140TYR A 120 | None | 1.15A | 5yodD-2ouaA:6.1 | 5yodD-2ouaA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2paj | PUTATIVECYTOSINE/GUANINEDEAMINASE (unidentified) |
PF01979(Amidohydro_1) | 4 | HIS A 77ALA A 338SER A 82GLY A 122 | None | 1.23A | 5yodD-2pajA:undetectable | 5yodD-2pajA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pw9 | PUTATIVE FORMATEDEHYDROGENASEACCESSORY PROTEIN (Desulfotaleapsychrophila) |
PF02634(FdhD-NarQ) | 4 | HIS A 168ALA A 189SER A 183GLY A 182 | None | 1.28A | 5yodD-2pw9A:undetectable | 5yodD-2pw9A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qve | TYROSINE AMINOMUTASE (Streptomycesglobisporus) |
PF00221(Lyase_aromatic) | 4 | HIS A 357ALA A 362SER A 446GLY A 151 | MDO A 152 ( 4.1A)NoneMDO A 152 ( 4.4A)MDO A 152 ( 2.4A) | 1.18A | 5yodD-2qveA:undetectable | 5yodD-2qveA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2sfa | SERINE PROTEINASE (Streptomycesfradiae) |
PF00089(Trypsin) | 4 | ALA A 6SER A 16GLY A 107TYR A 84 | None | 1.13A | 5yodD-2sfaA:6.8 | 5yodD-2sfaA:23.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x98 | ALKALINE PHOSPHATASE (Halobacteriumsalinarum) |
PF00245(Alk_phosphatase) | 4 | ALA A 47SER A 45GLY A 470TYR A 158 | None MG A1481 ( 2.3A)None MG A1481 (-4.7A) | 1.19A | 5yodD-2x98A:undetectable | 5yodD-2x98A:17.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xyb | LACCASE (Trametescinnabarina) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | HIS A 209ALA A 149SER A 204TYR A 152 | None | 1.13A | 5yodD-2xybA:undetectable | 5yodD-2xybA:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y3s | TAML (Streptomycessp. 307-9) |
PF01565(FAD_binding_4)PF08031(BBE) | 4 | HIS A 130ALA A 121GLY A 119TYR A 106 | FAD A 600 (-4.0A)FAD A 600 (-3.4A)NoneNone | 1.20A | 5yodD-2y3sA:undetectable | 5yodD-2y3sA:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ycb | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTOR (Methanothermobacterthermautotrophicus) |
PF07521(RMMBL)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 4 | ALA A 327SER A 333GLY A 332TYR A 310 | None | 1.19A | 5yodD-2ycbA:undetectable | 5yodD-2ycbA:13.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5f | DIHYDRODIPICOLINATESYNTHASE (Clostridiumbotulinum) |
PF00701(DHDPS) | 4 | HIS A 119ALA A 85SER A 86GLY A 79 | None | 1.23A | 5yodD-3a5fA:undetectable | 5yodD-3a5fA:24.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3af5 | PUTATIVEUNCHARACTERIZEDPROTEIN PH1404 (Pyrococcushorikoshii) |
PF07521(RMMBL)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 4 | ALA A 342SER A 348GLY A 347TYR A 325 | None | 1.15A | 5yodD-3af5A:undetectable | 5yodD-3af5A:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bi3 | ALPHA-KETOGLUTARATE-DEPENDENTDIOXYGENASE ALKB (Escherichiacoli) |
PF13532(2OG-FeII_Oxy_2) | 4 | ALA A 19SER A 182GLY A 180TYR A 109 | None | 1.05A | 5yodD-3bi3A:undetectable | 5yodD-3bi3A:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cf4 | ACETYL-COADECARBOXYLASE/SYNTHASE ALPHA SUBUNIT (Methanosarcinabarkeri) |
PF03063(Prismane) | 4 | HIS A 117ALA A 638SER A 640GLY A 113 | CMO A 812 (-4.5A)NoneNoneNone | 1.10A | 5yodD-3cf4A:undetectable | 5yodD-3cf4A:12.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ddl | XANTHORHODOPSIN (Salinibacterruber) |
PF01036(Bac_rhodopsin) | 4 | ALA A 146SER A 143GLY A 140TYR A 207 | NoneNoneNoneRET A1301 (-3.8A) | 1.10A | 5yodD-3ddlA:undetectable | 5yodD-3ddlA:24.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hbx | GLUTAMATEDECARBOXYLASE 1 (Arabidopsisthaliana) |
PF00282(Pyridoxal_deC) | 4 | HIS A 276ALA A 246SER A 274GLY A 125 | LLP A 277 ( 3.8A)LLP A 277 ( 3.3A)LLP A 277 ( 2.8A)LLP A 277 ( 3.2A) | 1.27A | 5yodD-3hbxA:undetectable | 5yodD-3hbxA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hij | DIHYDRODIPICOLINATESYNTHASE (Bacillusanthracis) |
PF00701(DHDPS) | 4 | HIS A 120ALA A 86SER A 87GLY A 80 | None | 1.15A | 5yodD-3hijA:undetectable | 5yodD-3hijA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmj | FATTY ACID SYNTHASESUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00109(ketoacyl-synt)PF01648(ACPS)PF02801(Ketoacyl-synt_C) | 4 | ALA A 683SER A 687GLY A 686TYR A 717 | None | 1.28A | 5yodD-3hmjA:undetectable | 5yodD-3hmjA:6.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ie1 | RIBONUCLEASETTHA0252 (Thermusthermophilus) |
PF00753(Lactamase_B)PF07521(RMMBL)PF10996(Beta-Casp) | 4 | ALA A 139SER A 145GLY A 144TYR A 123 | None | 1.17A | 5yodD-3ie1A:undetectable | 5yodD-3ie1A:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k40 | AROMATIC-L-AMINO-ACID DECARBOXYLASE (Drosophilamelanogaster) |
PF00282(Pyridoxal_deC) | 4 | HIS A 301ALA A 148SER A 311GLY A 146 | LLP A 302 ( 4.3A)LLP A 302 ( 3.3A)NoneNone | 1.11A | 5yodD-3k40A:undetectable | 5yodD-3k40A:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwu | SUCCINYLGLUTAMATEDESUCCINYLASE/ASPARTOACYLASE (Shewanellafrigidimarina) |
PF04952(AstE_AspA) | 4 | HIS A 181ALA A 245SER A 178GLY A 175 | UNL A 373 ( 3.7A)NoneNoneUNL A 373 ( 3.5A) | 1.21A | 5yodD-3lwuA:undetectable | 5yodD-3lwuA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ml3 | OUTER MEMBRANEPROTEIN ICSAAUTOTRANSPORTER (Shigellaflexneri) |
PF03212(Pertactin) | 4 | ALA A 652SER A 659GLY A 655TYR A 718 | None | 1.16A | 5yodD-3ml3A:undetectable | 5yodD-3ml3A:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3no5 | UNCHARACTERIZEDPROTEIN (Cupriaviduspinatubonensis) |
PF05853(BKACE) | 4 | HIS A 49SER A 83GLY A 85TYR A 119 | ZN A 275 (-3.3A) ZN A 275 ( 3.9A)NoneNone | 1.22A | 5yodD-3no5A:undetectable | 5yodD-3no5A:24.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oqn | CATABOLITE CONTROLPROTEIN A (Bacillussubtilis) |
PF00356(LacI)PF13377(Peripla_BP_3) | 4 | ALA A 146SER A 148GLY A 125TYR A 76 | None | 1.16A | 5yodD-3oqnA:undetectable | 5yodD-3oqnA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oqn | CATABOLITE CONTROLPROTEIN A (Bacillussubtilis) |
PF00356(LacI)PF13377(Peripla_BP_3) | 4 | ALA A 147SER A 148GLY A 125TYR A 76 | None | 1.24A | 5yodD-3oqnA:undetectable | 5yodD-3oqnA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pqu | TRANSFERRIN BINDINGPROTEIN B (Actinobacillussuis) |
PF01298(TbpB_B_D)PF17483(TbpB_C)PF17484(TbpB_A) | 4 | HIS A 114ALA A 330SER A 130GLY A 131 | None | 1.10A | 5yodD-3pquA:undetectable | 5yodD-3pquA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pxl | LACCASE (Trameteshirsuta) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | HIS A 209ALA A 149SER A 204TYR A 152 | None | 1.18A | 5yodD-3pxlA:undetectable | 5yodD-3pxlA:17.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3u1j | SERINE PROTEASE NS3 (Dengue virus) |
PF00949(Peptidase_S7) | 4 | HIS B 51SER B 135GLY B 151TYR B 161 | None | 0.48A | 5yodD-3u1jB:27.0 | 5yodD-3u1jB:54.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ufa | SERINE PROTEASE SPLA (Staphylococcusaureus) |
PF00089(Trypsin) | 4 | HIS A 39ALA A 171SER A 154GLY A 155 | VPF A 201 (-3.8A)VPF A 201 (-4.9A)VPF A 201 (-1.7A)None | 1.25A | 5yodD-3ufaA:10.7 | 5yodD-3ufaA:27.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vpi | TYPE VI SECRETIONEXPORTED 1 (Pseudomonasaeruginosa) |
no annotation | 4 | HIS A 91ALA A 114SER A 112GLY A 111 | None | 1.09A | 5yodD-3vpiA:undetectable | 5yodD-3vpiA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4amg | SNOGD (Streptomycesnogalater) |
PF06722(DUF1205) | 4 | HIS A 301ALA A 344SER A 241GLY A 242 | None | 1.18A | 5yodD-4amgA:undetectable | 5yodD-4amgA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4apl | APICAL MEMBRANEANTIGEN 1 (Neosporacaninum) |
PF02430(AMA-1) | 4 | HIS A 85ALA A 108SER A 87GLY A 88 | None | 1.21A | 5yodD-4aplA:undetectable | 5yodD-4aplA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bcx | AP-1 COMPLEX SUBUNITGAMMA-LIKE 2 (Homo sapiens) |
PF02883(Alpha_adaptinC2) | 4 | HIS A 765ALA A 735SER A 704GLY A 677 | None | 1.00A | 5yodD-4bcxA:undetectable | 5yodD-4bcxA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4be9 | STEROL ESTERASE (Ophiostomapiceae) |
PF00135(COesterase) | 4 | HIS A 272ALA A 300SER A 303GLY A 80 | None | 1.06A | 5yodD-4be9A:undetectable | 5yodD-4be9A:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eqa | PUTATIVEUNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
no annotation | 4 | HIS A 91ALA A 114SER A 112GLY A 111 | None | 1.16A | 5yodD-4eqaA:undetectable | 5yodD-4eqaA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f4m | PAPAIN PEPTIDOGLYCANAMIDASE EFFECTORTSE1 (Pseudomonasaeruginosa) |
no annotation | 4 | HIS A 91ALA A 114SER A 112GLY A 111 | None | 1.16A | 5yodD-4f4mA:undetectable | 5yodD-4f4mA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hea | NADH-QUINONEOXIDOREDUCTASESUBUNIT 13 (Thermusthermophilus) |
PF00361(Proton_antipo_M) | 4 | HIS M 222ALA M 89SER M 224GLY M 225 | None | 1.14A | 5yodD-4heaM:undetectable | 5yodD-4heaM:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jhv | LACCASE (Coriolopsiscaperata) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | HIS A 208ALA A 149SER A 203TYR A 152 | None | 1.27A | 5yodD-4jhvA:undetectable | 5yodD-4jhvA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mbg | CAAXFARNESYLTRANSFERASEALPHA SUBUNIT RAM2CAAXFARNESYLTRANSFERASEBETA SUBUNIT RAM1 (Aspergillusfumigatus;Aspergillusfumigatus) |
PF01239(PPTA)PF00432(Prenyltrans) | 4 | ALA B 201SER B 202GLY B 191TYR A 74 | K B 605 (-3.4A)NoneNoneNone | 1.20A | 5yodD-4mbgB:undetectable | 5yodD-4mbgB:17.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n0n | REPLICASEPOLYPROTEIN 1AB (Equinearteritis virus) |
PF01443(Viral_helicase1) | 4 | HIS A 29ALA A 16SER A 15GLY A 19 | ZN A 501 (-3.3A)None ZN A 501 ( 3.8A)None | 1.09A | 5yodD-4n0nA:undetectable | 5yodD-4n0nA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4og1 | ENOYL-COAHYDRATASE/ISOMERASE (Novosphingobiumaromaticivorans) |
PF00378(ECH_1) | 4 | HIS A 20ALA A 113SER A 59GLY A 60 | None | 1.22A | 5yodD-4og1A:undetectable | 5yodD-4og1A:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4opm | LIPASE (Acinetobacterbaumannii) |
PF12697(Abhydrolase_6) | 4 | HIS A 75ALA A 78SER A 105GLY A 106 | None | 1.20A | 5yodD-4opmA:undetectable | 5yodD-4opmA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q05 | ESTERASE E25 (unculturedbacterium) |
PF07859(Abhydrolase_3) | 4 | HIS A 312ALA A 120SER A 186GLY A 118 | None | 1.04A | 5yodD-4q05A:undetectable | 5yodD-4q05A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rqo | L-SERINE DEHYDRATASE (Legionellapneumophila) |
PF03313(SDH_alpha)PF03315(SDH_beta) | 4 | HIS A 380ALA A 350SER A 351GLY A 403 | None | 1.27A | 5yodD-4rqoA:undetectable | 5yodD-4rqoA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tqv | ALGS (Sphingomonassp.) |
PF00005(ABC_tran)PF03459(TOBE) | 4 | HIS C 345ALA C 299SER C 296GLY C 295 | None | 1.25A | 5yodD-4tqvC:undetectable | 5yodD-4tqvC:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u4e | THIOLASE (Sphaerobacterthermophilus) |
PF02803(Thiolase_C) | 4 | HIS A 366ALA A 254SER A 258GLY A 376 | None | 1.20A | 5yodD-4u4eA:undetectable | 5yodD-4u4eA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbt | PROBABLEHISTIDINOL-PHOSPHATEAMINOTRANSFERASE (Sinorhizobiummeliloti) |
PF00155(Aminotran_1_2) | 4 | ALA A 227SER A 43GLY A 46TYR A 274 | None | 1.21A | 5yodD-4wbtA:undetectable | 5yodD-4wbtA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y7p | ALKALINE D-PEPTIDASE (Bacillus cereus) |
PF00144(Beta-lactamase) | 4 | ALA A 149SER A 247GLY A 246TYR A 132 | None | 1.24A | 5yodD-4y7pA:undetectable | 5yodD-4y7pA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yiv | APICAL MEMBRANEANTIGEN AMA1 (Toxoplasmagondii) |
PF02430(AMA-1) | 4 | HIS A 91ALA A 114SER A 93GLY A 94 | None | 1.17A | 5yodD-4yivA:undetectable | 5yodD-4yivA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5abj | VP3 (Enterovirus A) |
PF00073(Rhv) | 4 | ALA C 208SER C 124GLY C 123TYR C 202 | None | 1.24A | 5yodD-5abjC:undetectable | 5yodD-5abjC:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cju | ISOBUTYRYL-COAMUTASE FUSED (Cupriavidusmetallidurans) |
PF01642(MM_CoA_mutase)PF02310(B12-binding)PF03308(ArgK) | 4 | HIS A1038ALA A 655SER A1074GLY A1076 | None | 1.27A | 5yodD-5cjuA:undetectable | 5yodD-5cjuA:9.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eno | MULTIDRUG EFFLUXPUMP SUBUNITACRB,MULTIDRUGEFFLUX PUMP SUBUNITACRB (Escherichiacoli) |
PF00873(ACR_tran) | 4 | ALA A 803SER A 802GLY A 787TYR A 790 | None | 1.19A | 5yodD-5enoA:undetectable | 5yodD-5enoA:13.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gj4 | SERINE PROTEASE NS3 (Zika virus) |
PF00949(Peptidase_S7) | 5 | HIS B 51ALA B 132SER B 135GLY B 151TYR B 161 | None | 0.61A | 5yodD-5gj4B:28.9 | 5yodD-5gj4B:99.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h5j | FERREDOXIN--NADPREDUCTASE (Zea mays) |
PF00175(NAD_binding_1) | 4 | ALA A 97SER A 111GLY A 110TYR A 67 | None | 1.18A | 5yodD-5h5jA:undetectable | 5yodD-5h5jA:20.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5idk | GENOMEPOLYPROTEIN,SERINEPROTEASE SUBUNITNS2B, SERINEPROTEASE NS3 (West Nile virus) |
PF00949(Peptidase_S7)PF01002(Flavi_NS2B) | 4 | HIS A1051SER A1135GLY A1151TYR A1161 | 6A8 A1201 (-3.3A)6A8 A1201 (-1.5A)6A8 A1201 (-4.2A)6A8 A1201 (-4.1A) | 0.38A | 5yodD-5idkA:24.4 | 5yodD-5idkA:52.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j56 | VHH SINGLE CHAINANTIBODY V1C7 (Vicugna pacos) |
PF07686(V-set) | 4 | ALA B 108SER B 53GLY B 38TYR B 115 | None | 1.27A | 5yodD-5j56B:undetectable | 5yodD-5j56B:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kck | ANTHRANILATESYNTHASE COMPONENT I (Streptococcuspneumoniae) |
PF00425(Chorismate_bind)PF04715(Anth_synt_I_N) | 4 | HIS A 81SER A 83GLY A 88TYR A 127 | None | 1.25A | 5yodD-5kckA:undetectable | 5yodD-5kckA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ke1 | OUTER MEMBRANEPROTEIN ICSAAUTOTRANSPORTER (Shigellaflexneri) |
PF03212(Pertactin)PF12951(PATR) | 4 | ALA A 652SER A 659GLY A 655TYR A 718 | None | 1.19A | 5yodD-5ke1A:undetectable | 5yodD-5ke1A:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mch | CELLOBIOHYDROLASECHBI (Daphnia pulex) |
PF00840(Glyco_hydro_7) | 4 | HIS A 61ALA A 26GLY A 23TYR A 191 | None | 1.19A | 5yodD-5mchA:undetectable | 5yodD-5mchA:17.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mg5 | 2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESISPROTEIN PHLC (Pseudomonasprotegens) |
no annotation | 4 | ALA C 34SER C 33GLY C 216TYR C 53 | None | 1.22A | 5yodD-5mg5C:undetectable | 5yodD-5mg5C:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ot1 | PULLULANASE TYPE II,GH13 FAMILY (Thermococcuskodakarensis) |
no annotation | 4 | HIS A 344SER A 379GLY A 378TYR A 386 | None | 1.28A | 5yodD-5ot1A:undetectable | 5yodD-5ot1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sga | PROTEINASE A (SGPA) (Streptomycesgriseus) |
PF00089(Trypsin) | 4 | ALA E 30SER E 43GLY E 140TYR E 120 | None | 1.11A | 5yodD-5sgaE:5.9 | 5yodD-5sgaE:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sv9 | BOR1P BORONTRANSPORTER (Saccharomycesmikatae) |
PF00955(HCO3_cotransp) | 4 | ALA A 351SER A 344GLY A 345TYR A 77 | None | 0.88A | 5yodD-5sv9A:undetectable | 5yodD-5sv9A:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t77 | PUTATIVE LIPID IIFLIPPASE MURJ (Thermosiphoafricanus) |
PF03023(MVIN) | 4 | ALA A 336SER A 395GLY A 340TYR A 257 | OLC A 535 ( 3.7A)NoneNoneNone | 1.18A | 5yodD-5t77A:undetectable | 5yodD-5t77A:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t77 | PUTATIVE LIPID IIFLIPPASE MURJ (Thermosiphoafricanus) |
PF03023(MVIN) | 4 | ALA A 391SER A 395GLY A 340TYR A 257 | None | 0.86A | 5yodD-5t77A:undetectable | 5yodD-5t77A:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9c | DTDP-4-DEHYDRORHAMNOSE REDUCTASE (Yersiniaenterocolitica) |
PF04321(RmlD_sub_bind) | 4 | ALA A 88SER A 137GLY A 134TYR A 100 | None | 1.01A | 5yodD-5u9cA:undetectable | 5yodD-5u9cA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgs | RCC1-LIKE GEXCHANGINGFACTOR-LIKE PROTEIN (Homo sapiens) |
PF00415(RCC1)PF13540(RCC1_2) | 4 | HIS A 455ALA A 113GLY A 452TYR A 291 | None | 1.20A | 5yodD-5xgsA:undetectable | 5yodD-5xgsA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xko | CYTIDINE/DEOXYCYTIDYLATE DEAMINASE,ZINC-BINDING REGION (Mycolicibacteriumsmegmatis) |
PF00383(dCMP_cyt_deam_1) | 4 | ALA A 18SER A 82GLY A 83TYR A 153 | NoneNoneCAC A 201 (-4.1A)None | 0.99A | 5yodD-5xkoA:undetectable | 5yodD-5xkoA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnz | CRED (Streptomycescremeus) |
no annotation | 4 | HIS A 237ALA A 195GLY A 193TYR A 202 | None | 1.24A | 5yodD-5xnzA:undetectable | 5yodD-5xnzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z95 | - (-) |
no annotation | 4 | HIS A 51ALA A 101SER A 97GLY A 23 | None | 1.28A | 5yodD-5z95A:undetectable | 5yodD-5z95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f9n | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTORSUBUNIT 1 (Homo sapiens) |
no annotation | 4 | ALA A1287SER A1290GLY A1293TYR A1283 | None | 1.24A | 5yodD-6f9nA:undetectable | 5yodD-6f9nA:undetectable |