SIMILAR PATTERNS OF AMINO ACIDS FOR 5YOD_B_BEZB201
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bh6 | SUBTILISIN DY (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 4 | ALA A 134SER A 132GLY A 131TYR A 171 | NoneNone1BH A 300 ( 4.8A)None | 1.18A | 5yodB-1bh6A:0.0 | 5yodB-1bh6A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c1d | L-PHENYLALANINEDEHYDROGENASE (Rhodococcus sp.) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | HIS A 275ALA A 336SER A 326GLY A 330 | None | 1.21A | 5yodB-1c1dA:0.0 | 5yodB-1c1dA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c3l | SUBTILISIN-CARLSBERG (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 4 | ALA A 134SER A 132GLY A 131TYR A 171 | None | 1.16A | 5yodB-1c3lA:0.0 | 5yodB-1c3lA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1coy | CHOLESTEROL OXIDASE (Brevibacteriumsterolicum) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | ALA A 223SER A 211GLY A 212TYR A 195 | None | 1.28A | 5yodB-1coyA:undetectable | 5yodB-1coyA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gns | SUBTILISIN BPN' (Bacillusamyloliquefaciens) |
PF00082(Peptidase_S8) | 4 | ALA A 134SER A 132GLY A 131TYR A 171 | None | 1.15A | 5yodB-1gnsA:0.0 | 5yodB-1gnsA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hkh | GAMMA LACTAMASE (Microbacterium) |
PF00561(Abhydrolase_1) | 4 | ALA A 197SER A 192GLY A 60TYR A 71 | None | 1.21A | 5yodB-1hkhA:0.0 | 5yodB-1hkhA:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hpg | GLUTAMIC ACIDSPECIFIC PROTEASE (Streptomycesgriseus) |
no annotation | 4 | ALA A 30SER A 43GLY A 140TYR A 120 | None | 1.16A | 5yodB-1hpgA:9.8 | 5yodB-1hpgA:24.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmo | HEPARIN COFACTOR II (Homo sapiens) |
PF00079(Serpin) | 4 | HIS A 159SER A 147GLY A 144TYR A 225 | None | 1.18A | 5yodB-1jmoA:0.0 | 5yodB-1jmoA:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1koa | TWITCHIN (Caenorhabditiselegans) |
PF00069(Pkinase)PF07679(I-set) | 4 | HIS A6089ALA A6264SER A6292TYR A6118 | None | 1.09A | 5yodB-1koaA:0.0 | 5yodB-1koaA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1leh | LEUCINEDEHYDROGENASE (Lysinibacillussphaericus) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | HIS A 274ALA A 334SER A 324GLY A 328 | None | 1.19A | 5yodB-1lehA:undetectable | 5yodB-1lehA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ns3 | NS3 PROTEASE (Hepacivirus C) |
PF02907(Peptidase_S29) | 4 | HIS A 57ALA A 156SER A 139GLY A 140 | None | 1.16A | 5yodB-1ns3A:12.8 | 5yodB-1ns3A:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pgu | ACTIN INTERACTINGPROTEIN 1 (Saccharomycescerevisiae) |
PF00400(WD40) | 4 | HIS A 62ALA A 41SER A 83GLY A 84 | None | 1.25A | 5yodB-1pguA:undetectable | 5yodB-1pguA:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1prz | RIBOSOMAL LARGESUBUNITPSEUDOURIDINESYNTHASE D (Escherichiacoli) |
PF00849(PseudoU_synth_2) | 4 | HIS A 202ALA A 200SER A 190GLY A 205 | None | 1.29A | 5yodB-1przA:undetectable | 5yodB-1przA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r1a | HUMAN RHINOVIRUS 1ACOAT PROTEIN(SUBUNIT VP1)HUMAN RHINOVIRUS 1ACOAT PROTEIN(SUBUNIT VP4) (Rhinovirus A;Rhinovirus A) |
PF00073(Rhv)PF02226(Pico_P1A) | 4 | HIS 1 245ALA 4 35SER 4 38GLY 4 39 | None | 1.27A | 5yodB-1r1a1:undetectable | 5yodB-1r1a1:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sqj | OLIGOXYLOGLUCANREDUCING-END-SPECIFIC CELLOBIOHYDROLASE (Geotrichum sp.M128) |
PF15899(BNR_6) | 4 | HIS A 543ALA A 505SER A 547GLY A 546 | None | 1.27A | 5yodB-1sqjA:undetectable | 5yodB-1sqjA:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t0a | 2C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Shewanellaoneidensis) |
PF02542(YgbB) | 4 | HIS A 44ALA A 73SER A 37GLY A 39 | ZN A 661 (-3.1A)NoneNoneNone | 1.12A | 5yodB-1t0aA:undetectable | 5yodB-1t0aA:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vjv | UBIQUITINCARBOXYL-TERMINALHYDROLASE 6 (Saccharomycescerevisiae) |
PF00443(UCH) | 4 | HIS A 438ALA A 441SER A 445GLY A 446 | None | 1.09A | 5yodB-1vjvA:undetectable | 5yodB-1vjvA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w5t | ORC2 (Aeropyrumpernix) |
PF09079(Cdc6_C)PF13401(AAA_22) | 4 | HIS A 211ALA A 214SER A 57GLY A 56 | None | 1.23A | 5yodB-1w5tA:undetectable | 5yodB-1w5tA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x42 | HYPOTHETICAL PROTEINPH0459 (Pyrococcushorikoshii) |
PF13419(HAD_2) | 4 | HIS A 117ALA A 164SER A 144GLY A 119 | None | 1.19A | 5yodB-1x42A:undetectable | 5yodB-1x42A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8t | HYPOTHETICAL PROTEINRV0983 (Mycobacteriumtuberculosis) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 4 | HIS A 49ALA A 186SER A 169GLY A 170 | None | 1.08A | 5yodB-1y8tA:6.1 | 5yodB-1y8tA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ahr | PUTATIVE PYRROLINECARBOXYLATEREDUCTASE (Streptococcuspyogenes) |
PF03807(F420_oxidored)PF14748(P5CR_dimer) | 4 | HIS A 51ALA A 48SER A 29GLY A 30 | NAP A1500 (-4.0A)NoneNoneNAP A1500 (-4.2A) | 1.05A | 5yodB-2ahrA:undetectable | 5yodB-2ahrA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cvz | 3-HYDROXYISOBUTYRATEDEHYDROGENASE (Thermusthermophilus) |
PF03446(NAD_binding_2)PF14833(NAD_binding_11) | 4 | HIS A 39ALA A 47SER A 45GLY A 44 | None | 1.18A | 5yodB-2cvzA:undetectable | 5yodB-2cvzA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e7j | SEP-TRNA:CYS-TRNASYNTHASE (Archaeoglobusfulgidus) |
PF05889(SepSecS) | 4 | HIS A 208ALA A 185SER A 206GLY A 218 | PLP A1209 (-3.5A)PLP A1209 ( 3.7A)PLP A1209 (-3.0A)None | 1.29A | 5yodB-2e7jA:undetectable | 5yodB-2e7jA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ea3 | CHYMOTRYPSIN (Cellulomonasbogoriensis) |
PF00089(Trypsin) | 4 | ALA A 8SER A 18GLY A 98TYR A 75 | None | 1.24A | 5yodB-2ea3A:10.6 | 5yodB-2ea3A:22.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fp7 | GENOME POLYPROTEIN (West Nile virus) |
PF00949(Peptidase_S7) | 4 | HIS B 51SER B 135GLY B 151TYR B 161 | None | 0.54A | 5yodB-2fp7B:27.9 | 5yodB-2fp7B:62.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gzl | 2-C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Escherichiacoli) |
PF02542(YgbB) | 4 | HIS A 42ALA A 71SER A 35GLY A 37 | ZN A 900 (-3.1A)2AA A 901 (-3.6A)2AA A 901 (-3.7A)None | 1.25A | 5yodB-2gzlA:undetectable | 5yodB-2gzlA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i3o | GAMMA-GLUTAMYLTRANSFERASE RELATEDPROTEIN (Thermoplasmaacidophilum) |
PF01019(G_glu_transpept) | 4 | ALA A 113SER A 115GLY A 77TYR A 231 | None | 1.06A | 5yodB-2i3oA:undetectable | 5yodB-2i3oA:17.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o2g | DIENELACTONEHYDROLASE (Trichormusvariabilis) |
PF01738(DLH) | 4 | HIS A 198ALA A 120SER A 121GLY A 146 | NoneSO4 A 223 (-3.6A)NoneNone | 1.28A | 5yodB-2o2gA:undetectable | 5yodB-2o2gA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oua | SERINE PROTEASE (Nocardiopsisalba) |
PF00089(Trypsin) | 4 | ALA A 34SER A 43GLY A 140TYR A 120 | None | 1.25A | 5yodB-2ouaA:10.1 | 5yodB-2ouaA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2paj | PUTATIVECYTOSINE/GUANINEDEAMINASE (unidentified) |
PF01979(Amidohydro_1) | 4 | HIS A 77ALA A 338SER A 82GLY A 122 | None | 1.27A | 5yodB-2pajA:undetectable | 5yodB-2pajA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pw9 | PUTATIVE FORMATEDEHYDROGENASEACCESSORY PROTEIN (Desulfotaleapsychrophila) |
PF02634(FdhD-NarQ) | 4 | HIS A 168ALA A 189SER A 183GLY A 182 | None | 1.14A | 5yodB-2pw9A:undetectable | 5yodB-2pw9A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2raq | CONSERVED PROTEINMTH889 (Methanothermobacterthermautotrophicus) |
PF02680(DUF211) | 4 | ALA A 68SER A 71GLY A 73TYR A 24 | None | 1.12A | 5yodB-2raqA:undetectable | 5yodB-2raqA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2sfa | SERINE PROTEINASE (Streptomycesfradiae) |
PF00089(Trypsin) | 4 | ALA A 6SER A 16GLY A 107TYR A 84 | None | 1.21A | 5yodB-2sfaA:10.0 | 5yodB-2sfaA:23.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vbf | BRANCHED-CHAINALPHA-KETOACIDDECARBOXYLASE (Lactococcuslactis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | ALA A 411SER A 414GLY A 58TYR A 406 | ALA A 411 ( 0.0A)SER A 414 ( 0.0A)GLY A 58 ( 0.0A)TYR A 406 ( 1.3A) | 1.27A | 5yodB-2vbfA:undetectable | 5yodB-2vbfA:15.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y3s | TAML (Streptomycessp. 307-9) |
PF01565(FAD_binding_4)PF08031(BBE) | 4 | HIS A 130ALA A 121GLY A 119TYR A 106 | FAD A 600 (-4.0A)FAD A 600 (-3.4A)NoneNone | 1.17A | 5yodB-2y3sA:undetectable | 5yodB-2y3sA:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ycb | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTOR (Methanothermobacterthermautotrophicus) |
PF07521(RMMBL)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 4 | ALA A 327SER A 333GLY A 332TYR A 310 | None | 1.12A | 5yodB-2ycbA:undetectable | 5yodB-2ycbA:13.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z36 | CYTOCHROME P450 TYPECOMPACTIN3'',4''-HYDROXYLASE (Nonomuraearecticatena) |
PF00067(p450) | 4 | HIS A 401SER A 395GLY A 393TYR A 398 | None | 1.11A | 5yodB-2z36A:undetectable | 5yodB-2z36A:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5f | DIHYDRODIPICOLINATESYNTHASE (Clostridiumbotulinum) |
PF00701(DHDPS) | 4 | HIS A 119ALA A 85SER A 86GLY A 79 | None | 1.28A | 5yodB-3a5fA:undetectable | 5yodB-3a5fA:24.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3af5 | PUTATIVEUNCHARACTERIZEDPROTEIN PH1404 (Pyrococcushorikoshii) |
PF07521(RMMBL)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 4 | ALA A 342SER A 348GLY A 347TYR A 325 | None | 1.08A | 5yodB-3af5A:undetectable | 5yodB-3af5A:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ak5 | HEMOGLOBIN-BINDINGPROTEASE HBP (Escherichiacoli) |
PF02395(Peptidase_S6) | 4 | HIS A 125ALA A 281SER A 259GLY A 260 | None | 1.12A | 5yodB-3ak5A:3.6 | 5yodB-3ak5A:11.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bb7 | INTERPAIN A (Prevotellaintermedia) |
PF01640(Peptidase_C10)PF13734(Inhibitor_I69) | 4 | ALA A 244SER A 231GLY A 228TYR A 235 | None | 1.16A | 5yodB-3bb7A:undetectable | 5yodB-3bb7A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bba | INTERPAIN A (Prevotellaintermedia) |
PF01640(Peptidase_C10) | 4 | ALA A 244SER A 231GLY A 228TYR A 235 | None | 1.19A | 5yodB-3bbaA:undetectable | 5yodB-3bbaA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bi3 | ALPHA-KETOGLUTARATE-DEPENDENTDIOXYGENASE ALKB (Escherichiacoli) |
PF13532(2OG-FeII_Oxy_2) | 4 | ALA A 19SER A 182GLY A 180TYR A 109 | None | 1.11A | 5yodB-3bi3A:undetectable | 5yodB-3bi3A:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bma | D-ALANYL-LIPOTEICHOIC ACID SYNTHETASE (Streptococcuspneumoniae) |
PF04914(DltD) | 4 | ALA A 110SER A 77GLY A 107TYR A 152 | NoneSO4 A 3 (-3.4A)SO4 A 3 (-3.5A)None | 0.97A | 5yodB-3bmaA:undetectable | 5yodB-3bmaA:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cf4 | ACETYL-COADECARBOXYLASE/SYNTHASE ALPHA SUBUNIT (Methanosarcinabarkeri) |
PF03063(Prismane) | 4 | HIS A 117ALA A 638SER A 640GLY A 113 | CMO A 812 (-4.5A)NoneNoneNone | 1.10A | 5yodB-3cf4A:undetectable | 5yodB-3cf4A:12.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d8x | THIOREDOXINREDUCTASE 1 (Saccharomycescerevisiae) |
PF07992(Pyr_redox_2) | 4 | HIS A 16ALA A 42SER A 11GLY A 10 | NoneNoneFAD A1001 (-4.5A)FAD A1001 (-3.5A) | 1.23A | 5yodB-3d8xA:undetectable | 5yodB-3d8xA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ddl | XANTHORHODOPSIN (Salinibacterruber) |
PF01036(Bac_rhodopsin) | 4 | ALA A 146SER A 143GLY A 140TYR A 207 | NoneNoneNoneRET A1301 (-3.8A) | 0.92A | 5yodB-3ddlA:undetectable | 5yodB-3ddlA:24.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fxi | TOLL-LIKE RECEPTOR 4 (Homo sapiens) |
PF13516(LRR_6)PF13855(LRR_8) | 4 | HIS A 148ALA A 121SER A 123GLY A 124 | None | 1.29A | 5yodB-3fxiA:undetectable | 5yodB-3fxiA:14.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hij | DIHYDRODIPICOLINATESYNTHASE (Bacillusanthracis) |
PF00701(DHDPS) | 4 | HIS A 120ALA A 86SER A 87GLY A 80 | None | 1.22A | 5yodB-3hijA:undetectable | 5yodB-3hijA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ie1 | RIBONUCLEASETTHA0252 (Thermusthermophilus) |
PF00753(Lactamase_B)PF07521(RMMBL)PF10996(Beta-Casp) | 4 | ALA A 139SER A 145GLY A 144TYR A 123 | None | 1.09A | 5yodB-3ie1A:undetectable | 5yodB-3ie1A:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k40 | AROMATIC-L-AMINO-ACID DECARBOXYLASE (Drosophilamelanogaster) |
PF00282(Pyridoxal_deC) | 4 | HIS A 301ALA A 148SER A 311GLY A 146 | LLP A 302 ( 4.3A)LLP A 302 ( 3.3A)NoneNone | 1.10A | 5yodB-3k40A:undetectable | 5yodB-3k40A:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kxp | ALPHA-(N-ACETYLAMINOMETHYLENE)SUCCINICACID HYDROLASE (Mesorhizobiumloti) |
PF12697(Abhydrolase_6) | 4 | ALA A 198SER A 196GLY A 68TYR A 79 | None | 0.83A | 5yodB-3kxpA:undetectable | 5yodB-3kxpA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ob8 | BETA-GALACTOSIDASE (Kluyveromyceslactis) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N) | 4 | HIS A 602ALA A 597SER A 595GLY A 599 | None | 1.25A | 5yodB-3ob8A:undetectable | 5yodB-3ob8A:11.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojy | COMPLEMENT COMPONENTC8 ALPHA CHAINCOMPLEMENT COMPONENTC8 BETA CHAIN (Homo sapiens;Homo sapiens) |
PF00057(Ldl_recept_a)PF00090(TSP_1)PF01823(MACPF)PF00057(Ldl_recept_a)PF00090(TSP_1)PF01823(MACPF) | 4 | HIS A 186ALA B 122SER B 123GLY B 134 | None | 1.23A | 5yodB-3ojyA:undetectable | 5yodB-3ojyA:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pqu | TRANSFERRIN BINDINGPROTEIN B (Actinobacillussuis) |
PF01298(TbpB_B_D)PF17483(TbpB_C)PF17484(TbpB_A) | 4 | HIS A 114ALA A 330SER A 130GLY A 131 | None | 1.24A | 5yodB-3pquA:undetectable | 5yodB-3pquA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3q | ALKALINE PHOSPHATASE (Sphingomonassp. BSAR-1) |
PF01663(Phosphodiest) | 4 | HIS A 93ALA A 344SER A 47GLY A 295 | None | 1.10A | 5yodB-3q3qA:undetectable | 5yodB-3q3qA:15.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3u1j | SERINE PROTEASE NS3 (Dengue virus) |
PF00949(Peptidase_S7) | 4 | HIS B 51SER B 135GLY B 151TYR B 161 | None | 0.62A | 5yodB-3u1jB:27.0 | 5yodB-3u1jB:54.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ufa | SERINE PROTEASE SPLA (Staphylococcusaureus) |
PF00089(Trypsin) | 4 | HIS A 39ALA A 171SER A 154GLY A 155 | VPF A 201 (-3.8A)VPF A 201 (-4.9A)VPF A 201 (-1.7A)None | 1.08A | 5yodB-3ufaA:10.7 | 5yodB-3ufaA:27.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ugv | ENOLASE (alphaproteobacteriumBAL199) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ALA A 105SER A 106GLY A 283TYR A 85 | None | 1.26A | 5yodB-3ugvA:undetectable | 5yodB-3ugvA:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vpi | TYPE VI SECRETIONEXPORTED 1 (Pseudomonasaeruginosa) |
no annotation | 4 | HIS A 91ALA A 114SER A 112GLY A 111 | None | 0.99A | 5yodB-3vpiA:undetectable | 5yodB-3vpiA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wks | O-PHOSPHO-L-SERYL-TRNA:CYS-TRNA SYNTHASE (Methanocaldococcusjannaschii) |
PF05889(SepSecS) | 4 | HIS A 233ALA A 210SER A 231GLY A 100 | LLP A 234 ( 3.5A)LLP A 234 ( 3.4A)LLP A 234 ( 2.9A)LLP A 234 ( 3.1A) | 1.21A | 5yodB-3wksA:undetectable | 5yodB-3wksA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b56 | ECTONUCLEOTIDEPYROPHOSPHATASE/PHOSPHODIESTERASE FAMILYMEMBER 1 (Mus musculus) |
PF01033(Somatomedin_B)PF01223(Endonuclease_NS)PF01663(Phosphodiest) | 4 | ALA A 374SER A 360GLY A 361TYR A 206 | None | 1.24A | 5yodB-4b56A:undetectable | 5yodB-4b56A:12.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bc7 | ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE,PEROXISOMAL (Cavia porcellus) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 4 | ALA A 496SER A 392GLY A 391TYR A 485 | None | 1.27A | 5yodB-4bc7A:undetectable | 5yodB-4bc7A:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bcx | AP-1 COMPLEX SUBUNITGAMMA-LIKE 2 (Homo sapiens) |
PF02883(Alpha_adaptinC2) | 4 | HIS A 765ALA A 735SER A 704GLY A 677 | None | 0.89A | 5yodB-4bcxA:undetectable | 5yodB-4bcxA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4be9 | STEROL ESTERASE (Ophiostomapiceae) |
PF00135(COesterase) | 4 | HIS A 272ALA A 300SER A 303GLY A 80 | None | 0.96A | 5yodB-4be9A:undetectable | 5yodB-4be9A:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cab | CATALASE (Deinococcusradiodurans) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | ALA A 203SER A 200GLY A 199TYR A 495 | None | 1.26A | 5yodB-4cabA:undetectable | 5yodB-4cabA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dxb | MALTOSE-BINDINGPERIPLASMIC PROTEIN,BETA-LACTAMASE TEMCHIMERA (Escherichiacoli) |
PF01547(SBP_bac_1)PF13354(Beta-lactamase2) | 4 | ALA A 301SER A 585GLY A 584TYR A 90 | None | 1.20A | 5yodB-4dxbA:undetectable | 5yodB-4dxbA:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eqa | PUTATIVEUNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
no annotation | 4 | HIS A 91ALA A 114SER A 112GLY A 111 | None | 1.14A | 5yodB-4eqaA:undetectable | 5yodB-4eqaA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f4m | PAPAIN PEPTIDOGLYCANAMIDASE EFFECTORTSE1 (Pseudomonasaeruginosa) |
no annotation | 4 | HIS A 91ALA A 114SER A 112GLY A 111 | None | 1.10A | 5yodB-4f4mA:undetectable | 5yodB-4f4mA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4inl | SERINE PROTEASE SPLD (Staphylococcusaureus) |
PF13365(Trypsin_2) | 4 | HIS A 39ALA A 173SER A 156GLY A 157 | None | 1.12A | 5yodB-4inlA:10.5 | 5yodB-4inlA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nov | XYLOSIDASE/ARABINOFURANOSIDASE XSA43E (Butyrivibrioproteoclasticus) |
PF04616(Glyco_hydro_43) | 4 | HIS A 228ALA A 190SER A 199GLY A 221 | None | 1.10A | 5yodB-4novA:undetectable | 5yodB-4novA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nql | AMSH-LIKE PROTEASESST2 (Schizosaccharomycespombe) |
PF01398(JAB) | 4 | HIS A 343ALA A 354SER A 351TYR A 411 | None | 1.04A | 5yodB-4nqlA:undetectable | 5yodB-4nqlA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4obu | PYRIDOXAL-DEPENDENTDECARBOXYLASE DOMAINPROTEIN ([Ruminococcus]gnavus) |
no annotation | 4 | HIS E 120ALA E 127SER E 124GLY E 123 | None | 1.27A | 5yodB-4obuE:undetectable | 5yodB-4obuE:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4opm | LIPASE (Acinetobacterbaumannii) |
PF12697(Abhydrolase_6) | 4 | HIS A 75ALA A 78SER A 105GLY A 106 | None | 1.07A | 5yodB-4opmA:undetectable | 5yodB-4opmA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q05 | ESTERASE E25 (unculturedbacterium) |
PF07859(Abhydrolase_3) | 4 | HIS A 312ALA A 120SER A 186GLY A 118 | None | 1.00A | 5yodB-4q05A:undetectable | 5yodB-4q05A:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rqo | L-SERINE DEHYDRATASE (Legionellapneumophila) |
PF03313(SDH_alpha)PF03315(SDH_beta) | 4 | HIS A 380ALA A 350SER A 351GLY A 403 | None | 1.25A | 5yodB-4rqoA:undetectable | 5yodB-4rqoA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u4e | THIOLASE (Sphaerobacterthermophilus) |
PF02803(Thiolase_C) | 4 | HIS A 366ALA A 254SER A 258GLY A 376 | None | 1.17A | 5yodB-4u4eA:undetectable | 5yodB-4u4eA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y7p | ALKALINE D-PEPTIDASE (Bacillus cereus) |
PF00144(Beta-lactamase) | 4 | ALA A 149SER A 247GLY A 246TYR A 132 | None | 1.22A | 5yodB-4y7pA:undetectable | 5yodB-4y7pA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yn5 | MANNANENDO-1,4-BETA-MANNOSIDASE (Bacillus sp.JAMB750) |
PF02156(Glyco_hydro_26) | 4 | ALA A 358SER A 61GLY A 62TYR A 401 | None | 1.22A | 5yodB-4yn5A:undetectable | 5yodB-4yn5A:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aho | 5' EXONUCLEASEAPOLLO (Homo sapiens) |
PF07522(DRMBL) | 4 | HIS A 36SER A 30GLY A 119TYR A 117 | ZN A1320 ( 3.4A)NoneNoneNone | 1.27A | 5yodB-5ahoA:undetectable | 5yodB-5ahoA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5but | KTR SYSTEM POTASSIUMUPTAKE PROTEIN B (Bacillussubtilis) |
PF02386(TrkH) | 4 | HIS I 227ALA I 308SER I 307GLY I 306 | None | 1.17A | 5yodB-5butI:undetectable | 5yodB-5butI:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cxu | FERULIC ACIDESTERASE AMCE1/FAE1A (Anaeromycesmucronatus) |
PF00756(Esterase) | 4 | ALA A 182SER A 156GLY A 64TYR A 122 | None | 0.99A | 5yodB-5cxuA:undetectable | 5yodB-5cxuA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey5 | LBCA-B (syntheticconstruct) |
PF00291(PALP) | 4 | HIS B 350ALA B 265SER B 296GLY B 256 | None | 1.15A | 5yodB-5ey5B:undetectable | 5yodB-5ey5B:19.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gj4 | SERINE PROTEASE NS3 (Zika virus) |
PF00949(Peptidase_S7) | 4 | HIS B 51ALA B 132GLY B 151TYR B 161 | None | 0.40A | 5yodB-5gj4B:28.8 | 5yodB-5gj4B:99.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gj4 | SERINE PROTEASE NS3 (Zika virus) |
PF00949(Peptidase_S7) | 4 | HIS B 51SER B 135GLY B 151TYR B 161 | None | 0.63A | 5yodB-5gj4B:28.8 | 5yodB-5gj4B:99.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h3h | ABHYDROLASEDOMAIN-CONTAININGPROTEIN (Exiguobacteriumantarcticum) |
PF00561(Abhydrolase_1)PF08386(Abhydrolase_4) | 4 | HIS A 248ALA A 123SER A 96GLY A 29 | F50 A 301 (-4.0A)NoneF50 A 301 (-2.4A)F50 A 301 (-3.4A) | 1.27A | 5yodB-5h3hA:undetectable | 5yodB-5h3hA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h5j | FERREDOXIN--NADPREDUCTASE (Zea mays) |
PF00175(NAD_binding_1) | 4 | ALA A 97SER A 111GLY A 110TYR A 67 | None | 1.12A | 5yodB-5h5jA:undetectable | 5yodB-5h5jA:20.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5idk | GENOMEPOLYPROTEIN,SERINEPROTEASE SUBUNITNS2B, SERINEPROTEASE NS3 (West Nile virus) |
PF00949(Peptidase_S7)PF01002(Flavi_NS2B) | 4 | HIS A1051SER A1135GLY A1151TYR A1161 | 6A8 A1201 (-3.3A)6A8 A1201 (-1.5A)6A8 A1201 (-4.2A)6A8 A1201 (-4.1A) | 0.51A | 5yodB-5idkA:24.5 | 5yodB-5idkA:52.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ot1 | PULLULANASE TYPE II,GH13 FAMILY (Thermococcuskodakarensis) |
no annotation | 4 | HIS A 344SER A 379GLY A 378TYR A 386 | None | 1.28A | 5yodB-5ot1A:undetectable | 5yodB-5ot1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sga | PROTEINASE A (SGPA) (Streptomycesgriseus) |
PF00089(Trypsin) | 4 | ALA E 30SER E 43GLY E 140TYR E 120 | None | 1.20A | 5yodB-5sgaE:10.3 | 5yodB-5sgaE:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t77 | PUTATIVE LIPID IIFLIPPASE MURJ (Thermosiphoafricanus) |
PF03023(MVIN) | 4 | ALA A 391SER A 395GLY A 340TYR A 257 | None | 0.99A | 5yodB-5t77A:undetectable | 5yodB-5t77A:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tch | TRYPTOPHAN SYNTHASEBETA CHAIN (Mycobacteriumtuberculosis) |
PF00291(PALP) | 4 | HIS B 367ALA B 282SER B 313GLY B 273 | None | 1.27A | 5yodB-5tchB:undetectable | 5yodB-5tchB:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tuk | TETRACYCLINEDESTRUCTASE TET(51) (unculturedbacterium) |
PF01494(FAD_binding_3) | 4 | HIS A 44ALA A 209SER A 207GLY A 220 | FAD A 402 (-3.8A)GOL A 401 (-4.2A)NoneNone | 1.29A | 5yodB-5tukA:undetectable | 5yodB-5tukA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9c | DTDP-4-DEHYDRORHAMNOSE REDUCTASE (Yersiniaenterocolitica) |
PF04321(RmlD_sub_bind) | 4 | ALA A 88SER A 137GLY A 134TYR A 100 | None | 1.06A | 5yodB-5u9cA:undetectable | 5yodB-5u9cA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vae | ACCESSORY SEC SYSTEMPROTEIN ASP1 (Streptococcusgordonii) |
no annotation | 4 | HIS A 465ALA A 481GLY A 469TYR A 485 | None | 1.25A | 5yodB-5vaeA:undetectable | 5yodB-5vaeA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vf6 | SINGLE CHAINVARIABLE FRAGMENT (Gallus gallus) |
no annotation | 4 | ALA A 26SER A 24GLY A 22TYR A 29 | None | 1.15A | 5yodB-5vf6A:undetectable | 5yodB-5vf6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x3j | GLYCOSIDE HYDROLASEFAMILY 31 (Kribbellaflavida) |
no annotation | 4 | ALA A 680SER A 694GLY A 695TYR A 677 | None | 1.11A | 5yodB-5x3jA:undetectable | 5yodB-5x3jA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xko | CYTIDINE/DEOXYCYTIDYLATE DEAMINASE,ZINC-BINDING REGION (Mycolicibacteriumsmegmatis) |
PF00383(dCMP_cyt_deam_1) | 4 | ALA A 18SER A 82GLY A 83TYR A 153 | NoneNoneCAC A 201 (-4.1A)None | 1.06A | 5yodB-5xkoA:undetectable | 5yodB-5xkoA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnz | CRED (Streptomycescremeus) |
no annotation | 4 | HIS A 237ALA A 195GLY A 193TYR A 202 | None | 1.29A | 5yodB-5xnzA:undetectable | 5yodB-5xnzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cey | BIFUNCTIONAL AAC/APH (Staphylococcusaureus) |
no annotation | 4 | HIS A 372SER A 397GLY A 395TYR A 244 | NoneNone MG A 702 ( 4.5A)None | 1.21A | 5yodB-6ceyA:2.2 | 5yodB-6ceyA:undetectable |