SIMILAR PATTERNS OF AMINO ACIDS FOR 5Y9Y_A_ACTA412_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h0h FORMATE
DEHYDROGENASE
SUBUNIT ALPHA

(Desulfovibrio
gigas) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		3 ARG A 172
PHE A 679
ARG A 734
 None
 1.25A 5y9yA-1h0hA:
0.0		 5y9yA-1h0hA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o94 TRIMETHYLAMINE
DEHYDROGENASE

(Methylophilus
methylotrophus) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		3 ARG A 343
PHE A 383
ARG A 406
 None
 1.07A 5y9yA-1o94A:
0.0		 5y9yA-1o94A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvr CLPB PROTEIN

(Thermus
thermophilus) 		PF00004
(AAA)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		3 ARG A 578
PHE A 613
ARG A 370
 None
 1.26A 5y9yA-1qvrA:
0.0		 5y9yA-1qvrA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1su3 INTERSTITIAL
COLLAGENASE

(Homo sapiens) 		PF00045
(Hemopexin)
PF00413
(Peptidase_M10)
PF01471
(PG_binding_1) 		3 ARG A 337
PHE A 368
ARG A 341
 None
 1.23A 5y9yA-1su3A:
0.0		 5y9yA-1su3A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uc8 LYSINE BIOSYNTHESIS
ENZYME

(Thermus
thermophilus) 		PF08443
(RimK) 		3 ARG A  10
PHE A 256
ARG A  55
 None
 1.19A 5y9yA-1uc8A:
0.0		 5y9yA-1uc8A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhn PUTATIVE FLAVIN
OXIDOREDUCTASE

(Thermotoga
maritima) 		PF01207
(Dus) 		3 ARG A 162
PHE A 193
ARG A 214
 FMN  A 322 ( 4.8A)
None
FMN  A 322 (-3.7A)
 1.19A 5y9yA-1vhnA:
0.0		 5y9yA-1vhnA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1via SHIKIMATE KINASE

(Campylobacter
jejuni) 		PF01202
(SKI) 		3 ARG A 134
PHE A  51
ARG A  60
 SO4  A 176 (-3.0A)
None
SO4  A 176 (-2.8A)
 0.94A 5y9yA-1viaA:
0.0		 5y9yA-1viaA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xrs D-LYSINE
5,6-AMINOMUTASE
ALPHA SUBUNIT

(Acetoanaerobium
sticklandii) 		PF09043
(Lys-AminoMut_A) 		3 ARG A 402
PHE A 142
ARG A 232
 None
 1.14A 5y9yA-1xrsA:
0.0		 5y9yA-1xrsA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2am4 ALPHA-1,3-MANNOSYL-G
LYCOPROTEIN
2-BETA-N-ACETYLGLUCO
SAMINYLTRANSFERASE

(Oryctolagus
cuniculus) 		PF03071
(GNT-I) 		3 ARG A 295
PHE A 326
ARG A 415
 None
 1.06A 5y9yA-2am4A:
0.0		 5y9yA-2am4A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cwe HYPOTHETICAL
TRANSCRIPTION
REGULATOR PROTEIN,
PH1932

(Pyrococcus
horikoshii) 		PF01022
(HTH_5) 		3 ARG A  23
PHE A 136
ARG A 104
 None
 0.93A 5y9yA-2cweA:
undetectable		 5y9yA-2cweA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2egz 3-DEHYDROQUINATE
DEHYDRATASE

(Aquifex
aeolicus) 		PF01487
(DHquinase_I) 		3 ARG A  30
PHE A 118
ARG A  61
 TLA  A4988 (-4.0A)
None
TLA  A4988 (-3.1A)
 1.21A 5y9yA-2egzA:
undetectable		 5y9yA-2egzA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f4o PEPTIDE N-GLYCANASE

(Mus musculus) 		PF01841
(Transglut_core) 		3 ARG A 325
PHE A 441
ARG A 387
 None
 1.10A 5y9yA-2f4oA:
undetectable		 5y9yA-2f4oA:
25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fml MUTT/NUDIX FAMILY
PROTEIN

(Enterococcus
faecalis) 		PF00293
(NUDIX) 		3 ARG A  63
PHE A  78
ARG A 120
 None
None
GOL  A 301 ( 4.8A)
 0.95A 5y9yA-2fmlA:
undetectable		 5y9yA-2fmlA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g1k SHIKIMATE KINASE

(Mycobacterium
tuberculosis) 		PF01202
(SKI) 		3 ARG A 136
PHE A  49
ARG A  58
 SKM  A 401 (-2.7A)
SKM  A 401 ( 4.9A)
SKM  A 401 (-2.9A)
 0.97A 5y9yA-2g1kA:
undetectable		 5y9yA-2g1kA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g9i F420-0:GAMMA-GLUTAMY
L LIGASE

(Archaeoglobus
fulgidus) 		PF01996
(F420_ligase) 		3 ARG A  29
PHE A   6
ARG A 219
 None
 1.07A 5y9yA-2g9iA:
undetectable		 5y9yA-2g9iA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2in5 HYPOTHETICAL
LIPOPROTEIN YMCC

(Escherichia
coli) 		PF11102
(YjbF) 		3 ARG A 111
PHE A 130
ARG A  75
 None
 0.96A 5y9yA-2in5A:
undetectable		 5y9yA-2in5A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j28 50S RIBOSOMAL
PROTEIN L2

(Escherichia
coli) 		PF00181
(Ribosomal_L2)
PF03947
(Ribosomal_L2_C) 		3 ARG C  62
PHE C  66
ARG C  86
 G  B1817 ( 2.6A)
None
G  B1817 ( 3.3A)
 0.90A 5y9yA-2j28C:
undetectable		 5y9yA-2j28C:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2khd UNCHARACTERIZED
PROTEIN VC_A0919

(Vibrio cholerae) 		PF04175
(DUF406) 		3 ARG A  96
PHE A  37
ARG A 100
 None
 1.18A 5y9yA-2khdA:
undetectable		 5y9yA-2khdA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p0l LIPOATE-PROTEIN
LIGASE A

(Streptococcus
agalactiae) 		PF03099
(BPL_LplA_LipB) 		3 ARG A 168
PHE A 265
ARG A  38
 None
 1.21A 5y9yA-2p0lA:
undetectable		 5y9yA-2p0lA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjt NICOTINAMIDE-NUCLEOT
IDE
ADENYLYLTRANSFERASE

(Francisella
tularensis) 		no annotation 3 ARG B 221
PHE B 236
ARG B 282
 MN  B 507 ( 4.8A)
AMP  B 602 (-3.4A)
None
 1.22A 5y9yA-2qjtB:
undetectable		 5y9yA-2qjtB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qop HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ACRR

(Escherichia
coli) 		PF00440
(TetR_N)
PF08361
(TetR_C_2) 		3 ARG A 192
PHE A  81
ARG A  90
 None
 1.00A 5y9yA-2qopA:
undetectable		 5y9yA-2qopA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qsf DNA REPAIR PROTEIN
RAD4

(Saccharomyces
cerevisiae) 		PF03835
(Rad4)
PF10403
(BHD_1)
PF10405
(BHD_3) 		3 ARG A 281
PHE A 425
ARG A 378
 None
 0.83A 5y9yA-2qsfA:
undetectable		 5y9yA-2qsfA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r94 2-KETO-3-DEOXY-(6-PH
OSPHO-)GLUCONATE
ALDOLASE

(Thermoproteus
tenax) 		PF00701
(DHDPS) 		3 ARG A  86
PHE A 146
ARG A 193
 None
 1.15A 5y9yA-2r94A:
undetectable		 5y9yA-2r94A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rcd UNCHARACTERIZED
PROTEIN

(Pectobacterium
atrosepticum) 		PF11533
(DUF3225) 		3 ARG A  66
PHE A  94
ARG A  96
 None
 1.21A 5y9yA-2rcdA:
undetectable		 5y9yA-2rcdA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2van DNA POLYMERSE BETA

(Rattus
norvegicus) 		PF10391
(DNA_pol_lambd_f)
PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		3 ARG A 182
PHE A 320
ARG A 333
 None
 1.22A 5y9yA-2vanA:
undetectable		 5y9yA-2vanA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w9m POLYMERASE X

(Deinococcus
radiodurans) 		PF14520
(HHH_5)
PF14716
(HHH_8) 		3 ARG A 189
PHE A 298
ARG A 304
 None
 1.08A 5y9yA-2w9mA:
undetectable		 5y9yA-2w9mA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ak4 NADH-DEPENDENT
QUINUCLIDINONE
REDUCTASE

(Agrobacterium
tumefaciens) 		PF13561
(adh_short_C2) 		3 ARG A 127
PHE A 119
ARG A  67
 None
 0.96A 5y9yA-3ak4A:
undetectable		 5y9yA-3ak4A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3blw ISOCITRATE
DEHYDROGENASE [NAD]
SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF00180
(Iso_dh) 		3 ARG A 274
PHE A 136
ARG A 129
 FLC  A1001 (-3.4A)
FLC  A1001 (-4.5A)
FLC  A1001 (-3.4A)
 1.11A 5y9yA-3blwA:
undetectable		 5y9yA-3blwA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ckb SUSD

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB) 		3 ARG A 466
PHE A 489
ARG A 437
 None
 0.98A 5y9yA-3ckbA:
undetectable		 5y9yA-3ckbA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e3m TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Ruegeria
pomeroyi) 		PF13377
(Peripla_BP_3) 		3 ARG A 204
PHE A  83
ARG A 200
 None
 1.23A 5y9yA-3e3mA:
undetectable		 5y9yA-3e3mA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fw8 RETICULINE OXIDASE

(Eschscholzia
californica) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		3 ARG A 209
PHE A 403
ARG A 221
 None
 1.10A 5y9yA-3fw8A:
undetectable		 5y9yA-3fw8A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gz8 MUTT/NUDIX FAMILY
PROTEIN

(Shewanella
oneidensis) 		PF00293
(NUDIX) 		3 ARG A  41
PHE A  56
ARG A  98
 APR  A 302 (-3.1A)
APR  A 302 (-3.5A)
APR  A 302 (-2.9A)
 0.90A 5y9yA-3gz8A:
undetectable		 5y9yA-3gz8A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9x MUTT/NUDIX FAMILY
PROTEIN

(Listeria
innocua) 		PF00293
(NUDIX) 		3 ARG A  51
PHE A  73
ARG A 113
 None
 0.93A 5y9yA-3i9xA:
undetectable		 5y9yA-3i9xA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jcm U4/U6 SMALL NUCLEAR
RIBONUCLEOPROTEIN
PRP4
U4/U6 SMALL NUCLEAR
RIBONUCLEOPROTEIN
PRP3

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF06544
(DUF1115)
PF08572
(PRP3) 		3 ARG B 135
PHE K 156
ARG B 379
 None
 1.04A 5y9yA-3jcmB:
undetectable		 5y9yA-3jcmB:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jq0 SUSD SUPERFAMILY
PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 ARG A 423
PHE A 473
ARG A 394
 None
 0.95A 5y9yA-3jq0A:
undetectable		 5y9yA-3jq0A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jq1 SUSD SUPERFAMILY
PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 ARG A 422
PHE A 449
ARG A 391
 None
 1.02A 5y9yA-3jq1A:
undetectable		 5y9yA-3jq1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l22 SUSD SUPERFAMILY
PROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 ARG A 381
PHE A 412
ARG A 349
 None
 0.97A 5y9yA-3l22A:
undetectable		 5y9yA-3l22A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3npf PUTATIVE
DIPEPTIDYL-PEPTIDASE
VI

(Bacteroides
ovatus) 		PF00877
(NLPC_P60) 		3 ARG A 169
PHE A 212
ARG A 134
 None
 1.02A 5y9yA-3npfA:
undetectable		 5y9yA-3npfA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nqp SUSD SUPERFAMILY
PROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 ARG A 436
PHE A 470
ARG A 405
 None
 1.03A 5y9yA-3nqpA:
undetectable		 5y9yA-3nqpA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogk CORONATINE-INSENSITI
VE PROTEIN 1

(Arabidopsis
thaliana) 		no annotation 3 ARG B 409
PHE B  89
ARG B  85
 PO4  B1101 ( 3.1A)
OGK  B1100 (-3.4A)
OGK  B1100 ( 2.6A)
 1.17A 5y9yA-3ogkB:
undetectable		 5y9yA-3ogkB:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rj2 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Singapore
grouper
iridovirus) 		no annotation 3 ARG X 133
PHE X  62
ARG X  96
 None
 1.23A 5y9yA-3rj2X:
undetectable		 5y9yA-3rj2X:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rmj 2-ISOPROPYLMALATE
SYNTHASE

(Neisseria
meningitidis) 		PF00682
(HMGL-like) 		3 ARG A  81
PHE A  49
ARG A  77
 None
 1.16A 5y9yA-3rmjA:
undetectable		 5y9yA-3rmjA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3smt HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3

(Homo sapiens) 		PF00856
(SET)
PF09273
(Rubis-subs-bind) 		3 ARG A 253
PHE A  78
ARG A  74
 SAM  A1000 (-2.7A)
None
SAM  A1000 (-2.8A)
 1.25A 5y9yA-3smtA:
undetectable		 5y9yA-3smtA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uxm THYMIDYLATE KINASE

(Pseudomonas
aeruginosa) 		PF02223
(Thymidylate_kin) 		3 ARG A 154
PHE A 162
ARG A 109
 None
 0.99A 5y9yA-3uxmA:
undetectable		 5y9yA-3uxmA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v68 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF10869
(DUF2666) 		3 ARG A 107
PHE A 118
ARG A 227
 None
 1.09A 5y9yA-3v68A:
undetectable		 5y9yA-3v68A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzi CRISPR-ASSOCIATED
PROTEIN CAS5, DVULG
SUBTYPE

(Xanthomonas
oryzae) 		PF09704
(Cas_Cas5d) 		3 ARG A  25
PHE A 159
ARG A  69
 None
 1.16A 5y9yA-3vziA:
undetectable		 5y9yA-3vziA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzi CRISPR-ASSOCIATED
PROTEIN CAS5, DVULG
SUBTYPE

(Xanthomonas
oryzae) 		PF09704
(Cas_Cas5d) 		3 ARG A 104
PHE A 159
ARG A  69
 None
 0.84A 5y9yA-3vziA:
undetectable		 5y9yA-3vziA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ziu LEUCYL-TRNA
SYNTHETASE

(Mycoplasma
mobile) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		3 ARG A 434
PHE A  28
ARG A  68
 None
 1.23A 5y9yA-3ziuA:
undetectable		 5y9yA-3ziuA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b61 ALGINATE PRODUCTION
PROTEIN ALGE

(Pseudomonas
aeruginosa) 		PF13372
(Alginate_exp) 		3 ARG A 353
PHE A 483
ARG A 371
 None
 1.22A 5y9yA-4b61A:
undetectable		 5y9yA-4b61A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bx0 PYRIDOXAL PHOSPHATE
PHOSPHATASE

(Mus musculus) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		3 ARG A 119
PHE A 111
ARG A 154
 None
 1.08A 5y9yA-4bx0A:
undetectable		 5y9yA-4bx0A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eys MCCC FAMILY PROTEIN

(Streptococcus
pneumoniae) 		PF02016
(Peptidase_S66) 		3 ARG A 319
PHE A 175
ARG A 184
 AMP  A 401 (-4.0A)
AMP  A 401 (-3.8A)
None
 1.23A 5y9yA-4eysA:
undetectable		 5y9yA-4eysA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f53 SUSD HOMOLOG

(Bacteroides
ovatus) 		PF12741
(SusD-like) 		3 ARG A 471
PHE A 443
ARG A 370
 None
 1.15A 5y9yA-4f53A:
undetectable		 5y9yA-4f53A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fd4 ARYLALKYLAMINE
N-ACETYLTRANSFERASE
LIKE 5B

(Aedes aegypti) 		PF00583
(Acetyltransf_1) 		3 ARG A  13
PHE A  72
ARG A  10
 None
 1.17A 5y9yA-4fd4A:
undetectable		 5y9yA-4fd4A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hoz SUCROSE ISOMERASE

(Erwinia
rhapontici) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 ARG A 460
PHE A 186
ARG A 456
 GLC  A 703 ( 4.6A)
GLC  A 703 (-4.8A)
GLC  A 703 ( 2.9A)
 1.25A 5y9yA-4hozA:
undetectable		 5y9yA-4hozA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ict CYTOCHROME P450 121

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		3 ARG A 381
PHE A 161
ARG A 134
 SO4  A 404 (-3.6A)
SO4  A 404 (-4.5A)
SO4  A 404 (-2.7A)
 0.93A 5y9yA-4ictA:
undetectable		 5y9yA-4ictA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l7t NANU SIALIC ACID
BINDING PROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 ARG A 416
PHE A 464
ARG A 387
 None
 1.01A 5y9yA-4l7tA:
undetectable		 5y9yA-4l7tA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lls GERANYLTRANSTRANSFER
ASE

(Roseobacter
denitrificans) 		PF00348
(polyprenyl_synt) 		3 ARG A  92
PHE A  17
ARG A  42
 IPE  A 301 (-3.8A)
None
None
 0.94A 5y9yA-4llsA:
undetectable		 5y9yA-4llsA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mru SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12741
(SusD-like) 		3 ARG A 459
PHE A 431
ARG A 363
 None
 1.21A 5y9yA-4mruA:
undetectable		 5y9yA-4mruA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nc2 TOXIN B
B39 VHH

(Clostridioides
difficile;
Lama glama) 		PF01473
(CW_binding_1)
PF07686
(V-set) 		3 ARG B 104
PHE A  18
ARG A  12
 None
 1.24A 5y9yA-4nc2B:
undetectable		 5y9yA-4nc2B:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ny4 CYTOCHROME P450 3A4

(Homo sapiens) 		PF00067
(p450) 		3 ARG A 106
PHE A  74
ARG A 372
 None
 1.23A 5y9yA-4ny4A:
undetectable		 5y9yA-4ny4A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o01 BACTERIOPHYTOCHROME

(Deinococcus
radiodurans) 		PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2) 		3 ARG A 442
PHE A 327
ARG A 364
 None
 1.24A 5y9yA-4o01A:
undetectable		 5y9yA-4o01A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pv1 CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT

(Mastigocladus
laminosus) 		PF00355
(Rieske)
PF08802
(CytB6-F_Fe-S) 		3 ARG D 100
PHE D 124
ARG D  78
 None
 1.19A 5y9yA-4pv1D:
undetectable		 5y9yA-4pv1D:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pyh PHOSPHOGLUCAN
PHOSPHATASE DSP4,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00782
(DSPc)
PF16561
(AMPK1_CBM) 		3 ARG A 349
PHE A 304
ARG A 173
 None
 1.08A 5y9yA-4pyhA:
undetectable		 5y9yA-4pyhA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9d BENZOYLFORMATE
DECARBOXYLASE

(Mycolicibacterium
smegmatis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		3 ARG A 422
PHE A 398
ARG A 426
 None
 1.06A 5y9yA-4q9dA:
undetectable		 5y9yA-4q9dA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0k DIPEPTIDYL-PEPTIDASE
VI

(Bacteroides
thetaiotaomicron) 		PF00877
(NLPC_P60) 		3 ARG A 169
PHE A 212
ARG A 134
 None
 1.03A 5y9yA-4r0kA:
undetectable		 5y9yA-4r0kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8u LINKER L2

(Glossoscolex
paulistus) 		PF00057
(Ldl_recept_a)
PF16915
(Eryth_link_C) 		3 ARG N 130
PHE N 173
ARG N 216
 None
 0.98A 5y9yA-4u8uN:
undetectable		 5y9yA-4u8uN:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ufs LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 5
R-SPONDIN-2

(Homo sapiens;
Homo sapiens) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13855
(LRR_8)
PF15913
(Furin-like_2) 		3 ARG A 144
PHE B  60
ARG B  86
 None
 1.23A 5y9yA-4ufsA:
undetectable		 5y9yA-4ufsA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wcx BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED

(Thermoanaerobacter
italicus) 		PF04055
(Radical_SAM)
PF06968
(BATS) 		3 ARG A 273
PHE A 318
ARG A 271
 None
 1.13A 5y9yA-4wcxA:
undetectable		 5y9yA-4wcxA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wsq AP2-ASSOCIATED
PROTEIN KINASE 1

(Homo sapiens) 		PF00069
(Pkinase) 		3 ARG A  37
PHE A  77
ARG A  75
 None
 1.20A 5y9yA-4wsqA:
undetectable		 5y9yA-4wsqA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0a SHIKIMATE KINASE

(Acinetobacter
baumannii) 		PF01202
(SKI) 		3 ARG A 153
PHE A  65
ARG A  74
 SKM  A 201 (-2.8A)
SKM  A 201 ( 4.6A)
SKM  A 201 (-3.0A)
 0.98A 5y9yA-4y0aA:
undetectable		 5y9yA-4y0aA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxb INSULIN RECEPTOR

(Homo sapiens) 		PF00041
(fn3)
PF00757
(Furin-like)
PF01030
(Recep_L_domain) 		3 ARG E 870
PHE E 823
ARG E 873
 None
 0.98A 5y9yA-4zxbE:
undetectable		 5y9yA-4zxbE:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aa5 NIFE-HYDROGENASE
SMALL SUBUNIT, HOFK
NIFE-HYDROGENASE
LARGE SUBUNIT, HOFG

(Cupriavidus
necator;
Cupriavidus
necator) 		PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C)
PF00374
(NiFeSe_Hases) 		3 ARG C 203
PHE A 293
ARG C  79
 SF4  A 502 (-3.5A)
None
None
 1.01A 5y9yA-5aa5C:
undetectable		 5y9yA-5aa5C:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aga DNA POLYMERASE THETA

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 ARG A 856
PHE A 839
ARG A 396
 None
 1.22A 5y9yA-5agaA:
undetectable		 5y9yA-5agaA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah5 LEUCINE--TRNA LIGASE

(Agrobacterium
tumefaciens) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2) 		3 ARG A 596
PHE A  22
ARG A  62
 None
 1.18A 5y9yA-5ah5A:
undetectable		 5y9yA-5ah5A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c78 ATP-DRIVEN FLIPPASE
PGLK

(Campylobacter
jejuni) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		3 ARG A 302
PHE A  94
ARG A 309
 None
 1.23A 5y9yA-5c78A:
undetectable		 5y9yA-5c78A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dgo CELL DIVISION
CONTROL PROTEIN 45
HOMOLOG

(Homo sapiens) 		PF02724
(CDC45) 		3 ARG A 255
PHE A 203
ARG A 251
 None
 1.03A 5y9yA-5dgoA:
undetectable		 5y9yA-5dgoA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dl5 MEMBRANE PROTEIN

(Acinetobacter
baumannii) 		PF03573
(OprD) 		3 ARG A  26
PHE A 298
ARG A 126
 C8E  A 501 (-2.9A)
None
C8E  A 501 (-3.9A)
 1.17A 5y9yA-5dl5A:
undetectable		 5y9yA-5dl5A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dot CARBAMOYL-PHOSPHATE
SYNTHASE [AMMONIA],
MITOCHONDRIAL

(Homo sapiens) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain)
PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		3 ARG A1089
PHE A1169
ARG A1129
 None
 1.24A 5y9yA-5dotA:
undetectable		 5y9yA-5dotA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e76 SUSD-LIKE PROTEIN
BACOVA_02651

(Bacteroides
ovatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 ARG A 420
PHE A 442
ARG A 386
 None
 0.90A 5y9yA-5e76A:
undetectable		 5y9yA-5e76A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE

(Thermus
thermophilus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A 223
PHE A 251
ARG A 221
 None
 1.21A 5y9yA-5g3fA:
undetectable		 5y9yA-5g3fA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gwe CYTOCHROME P450

(Corynebacterium
glutamicum) 		PF00067
(p450) 		3 ARG A 306
PHE A  65
ARG A 444
 SO4  A 503 (-2.7A)
SO4  A 503 (-4.4A)
SO4  A 503 (-3.1A)
 0.87A 5y9yA-5gweA:
undetectable		 5y9yA-5gweA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i47 RIMK DOMAIN PROTEIN
ATP-GRASP

(Sphaerobacter
thermophilus) 		PF08443
(RimK) 		3 ARG A  12
PHE A 254
ARG A  55
 None
 1.05A 5y9yA-5i47A:
undetectable		 5y9yA-5i47A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jk7 PROTEIN VPRBP

(Homo sapiens) 		no annotation 3 ARG C1247
PHE C1230
ARG C1191
 None
 1.14A 5y9yA-5jk7C:
undetectable		 5y9yA-5jk7C:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxm PRIB

(Streptomyces
sp. RM-5-8) 		PF11991
(Trp_DMAT) 		3 ARG A 316
PHE A  85
ARG A 290
 TRS  A 501 ( 4.5A)
TRS  A 501 (-3.9A)
None
 1.16A 5y9yA-5jxmA:
undetectable		 5y9yA-5jxmA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc5 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL
NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1

(Bos taurus;
Bos taurus) 		PF01058
(Oxidored_q6)
PF00146
(NADHdh) 		3 ARG H  25
PHE H 224
ARG B  77
 None
 1.05A 5y9yA-5lc5H:
undetectable		 5y9yA-5lc5H:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lx8 SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 ARG A 457
PHE A 503
ARG A 424
 None
 1.02A 5y9yA-5lx8A:
undetectable		 5y9yA-5lx8A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofq CYTOCHROME P450

(Bacillus
megaterium) 		PF00067
(p450) 		3 ARG A  49
PHE A  55
ARG A  44
 None
 1.14A 5y9yA-5ofqA:
undetectable		 5y9yA-5ofqA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ovn POL PROTEIN
POL PROTEIN

(Feline
immunodeficiency
virus;
Feline
immunodeficiency
virus) 		no annotation
no annotation 		3 ARG A 172
PHE B 143
ARG B 141
 None
 1.20A 5y9yA-5ovnA:
undetectable		 5y9yA-5ovnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u03 CTP SYNTHASE 1

(Homo sapiens) 		PF00117
(GATase)
PF06418
(CTP_synth_N) 		3 ARG A  81
PHE A  59
ARG A 532
 None
 1.22A 5y9yA-5u03A:
undetectable		 5y9yA-5u03A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vft 26S PROTEASOME
REGULATORY SUBUNIT 8

(Homo sapiens) 		no annotation 3 ARG C 229
PHE C 283
ARG C 232
 None
 1.11A 5y9yA-5vftC:
undetectable		 5y9yA-5vftC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vys GDP-MANNOSE
4,6-DEHYDRATASE /
GDP-4-AMINO-4,6-DIDE
OXY-D-MANNOSE
FORMYLTRANSFERASE

(Brucella
melitensis) 		PF00551
(Formyl_trans_N) 		3 ARG A  88
PHE A 165
ARG A  45
 GDP  A 303 (-3.0A)
GDP  A 303 ( 4.5A)
GDP  A 303 (-2.6A)
 1.14A 5y9yA-5vysA:
undetectable		 5y9yA-5vysA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjn CYTOCHROME P450

(Corynebacterium
glutamicum) 		PF00067
(p450) 		3 ARG A 279
PHE A  38
ARG A 417
 None
 0.78A 5y9yA-5xjnA:
undetectable		 5y9yA-5xjnA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xpg UNCHARACTERIZED
PROTEIN

(Thermus
thermophilus) 		no annotation 3 ARG A 335
PHE A 647
ARG A 444
 None
C  G  19 ( 4.7A)
G  G  20 ( 4.4A)
 1.08A 5y9yA-5xpgA:
undetectable		 5y9yA-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xs9 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR

(Mycolicibacterium
smegmatis) 		no annotation 3 ARG A 150
PHE A 143
ARG A 168
 None
 1.19A 5y9yA-5xs9A:
undetectable		 5y9yA-5xs9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi UNCHARACTERIZED
PROTEIN
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis) 		PF00333
(Ribosomal_S5)
PF03719
(Ribosomal_S5_C)
PF00163
(Ribosomal_S4)
PF01479
(S4) 		3 ARG J  51
PHE C 212
ARG J  55
 None
A  2   1 ( 3.3A)
None
 0.81A 5y9yA-5xyiJ:
undetectable		 5y9yA-5xyiJ:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT

(Methylobacillus
sp. KY4400) 		no annotation 3 ARG B 113
PHE B  42
ARG B 115
 SO4  B 403 ( 2.4A)
None
FAD  B 401 ( 3.5A)
 1.08A 5y9yA-5y6qB:
undetectable		 5y9yA-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yfb DIPEPTIDYL PEPTIDASE
3

(Armillaria
tabescens) 		no annotation 3 ARG A 649
PHE A 163
ARG A  10
 None
 1.18A 5y9yA-5yfbA:
undetectable		 5y9yA-5yfbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yud BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 1E
PHASE 2
FLAGELLIN,FLAGELLIN

(Mus musculus;
Salmonella
enterica) 		no annotation
no annotation 		3 ARG A 110
PHE A  19
ARG C 495
 None
 0.96A 5y9yA-5yudA:
undetectable		 5y9yA-5yudA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6brs PUTATIVE ZINC
PROTEASE

(Pectobacterium
atrosepticum) 		no annotation 3 ARG A 870
PHE A 853
ARG A 860
 None
 1.19A 5y9yA-6brsA:
undetectable		 5y9yA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d95 -

(-) 		no annotation 3 ARG A  97
PHE A  60
ARG A 117
 None
 1.15A 5y9yA-6d95A:
undetectable		 5y9yA-6d95A:
undetectable