SIMILAR PATTERNS OF AMINO ACIDS FOR 5Y7P_G_CHDG401_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i6a | HYDROGENPEROXIDE-INDUCIBLEGENES ACTIVATOR (Escherichiacoli) |
PF03466(LysR_substrate) | 5 | LEU A 120ILE A 110LEU A 124ALA A 143LEU A 270 | None | 1.24A | 5y7pG-1i6aA:undetectable | 5y7pG-1i6aA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iay | 1-AMINOCYCLOPROPANE-1-CARBOXYLATESYNTHASE 2 (Solanumlycopersicum) |
PF00155(Aminotran_1_2) | 5 | ILE A 102LEU A 276ALA A 242LEU A 332GLU A 255 | None | 1.15A | 5y7pG-1iayA:0.0 | 5y7pG-1iayA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqo | PHOSPHOENOLPYRUVATECARBOXYLASE (Zea mays) |
PF00311(PEPcase) | 5 | LEU A 187ILE A 756ASN A 107ALA A 964LEU A 103 | None | 1.14A | 5y7pG-1jqoA:0.0 | 5y7pG-1jqoA:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lam | LEUCINEAMINOPEPTIDASE (Bos taurus) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 5 | LEU A 343ILE A 355LEU A 448ALA A 433LEU A 402 | None | 1.24A | 5y7pG-1lamA:0.0 | 5y7pG-1lamA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pgv | TROPOMODULIN TMD-1 (Caenorhabditiselegans) |
no annotation | 5 | LEU A 309ILE A 258LEU A 272ALA A 328GLU A 308 | None | 1.20A | 5y7pG-1pgvA:undetectable | 5y7pG-1pgvA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pie | GALACTOKINASE (Lactococcuslactis) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 5 | LEU A 136ILE A 355PHE A 52ALA A 186LEU A 182 | NoneNoneNoneNoneGLA A 400 ( 4.3A) | 1.27A | 5y7pG-1pieA:0.0 | 5y7pG-1pieA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pn5 | NACHT-, LRR- ANDPYD-CONTAININGPROTEIN 2 (Homo sapiens) |
PF02758(PYRIN) | 5 | LEU A 74LEU A 85LEU A 127ALA A 128LEU A 115 | None | 1.22A | 5y7pG-1pn5A:undetectable | 5y7pG-1pn5A:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pz1 | GENERAL STRESSPROTEIN 69 (Bacillussubtilis) |
PF00248(Aldo_ket_red) | 5 | LEU A 290ILE A 261LEU A 206ALA A 277LEU A 269 | NoneNoneNAP A 500 (-3.9A)NoneNone | 1.06A | 5y7pG-1pz1A:0.0 | 5y7pG-1pz1A:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qrz | PLASMINOGEN (Homo sapiens) |
PF00089(Trypsin) | 5 | ILE A 593LEU A 649LEU A 605ALA A 602GLU A 724 | None | 1.20A | 5y7pG-1qrzA:0.0 | 5y7pG-1qrzA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r9l | GLYCINEBETAINE-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli) |
PF04069(OpuAC) | 5 | TYR A 96ILE A 111LEU A 150ALA A 145LEU A 213 | None | 1.17A | 5y7pG-1r9lA:0.0 | 5y7pG-1r9lA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rty | YVQK PROTEIN (Bacillussubtilis) |
PF01923(Cob_adeno_trans) | 5 | LEU A 93ILE A 40PHE A 68LEU A 85GLU A 94 | None | 1.09A | 5y7pG-1rtyA:undetectable | 5y7pG-1rtyA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t9h | PROBABLE GTPASE ENGC (Bacillussubtilis) |
PF03193(RsgA_GTPase)PF16745(RsgA_N) | 5 | TYR A 137ILE A 113PHE A 100LEU A 101ALA A 95 | NoneNoneNoneNone CA A 415 ( 4.4A) | 1.20A | 5y7pG-1t9hA:undetectable | 5y7pG-1t9hA:25.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v4a | GLUTAMATE-AMMONIA-LIGASEADENYLYLTRANSFERASE (Escherichiacoli) |
PF03710(GlnE)PF08335(GlnD_UR_UTase) | 5 | ILE A 329LEU A 362LEU A 359ALA A 355GLU A 113 | None | 1.22A | 5y7pG-1v4aA:undetectable | 5y7pG-1v4aA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wl1 | OCTOPRENYL-DIPHOSPHATE SYNTHASE (Thermotogamaritima) |
PF00348(polyprenyl_synt) | 5 | ILE A 20PHE A 27LEU A 72LEU A 111ALA A 108 | None | 1.06A | 5y7pG-1wl1A:undetectable | 5y7pG-1wl1A:24.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y9j | SEC1 FAMILY DOMAINCONTAINING PROTEIN 1 (Rattusnorvegicus) |
PF00995(Sec1) | 5 | TYR A 145ILE A 10ASN A 112ALA A 17LEU A 18 | None | 1.23A | 5y7pG-1y9jA:undetectable | 5y7pG-1y9jA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yqd | SINAPYL ALCOHOLDEHYDROGENASE (Populustremuloides) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | LEU A 357ILE A 74LEU A 68ALA A 17LEU A 25 | None | 1.13A | 5y7pG-1yqdA:undetectable | 5y7pG-1yqdA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0i | DEHYDROGENASE (Pyrococcushorikoshii) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | ILE A 205LEU A 165LEU A 187ALA A 189GLU A 196 | None | 1.02A | 5y7pG-2d0iA:undetectable | 5y7pG-2d0iA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0i | DEHYDROGENASE (Pyrococcushorikoshii) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | LEU A 197LEU A 165LEU A 187ALA A 189GLU A 196 | None | 1.17A | 5y7pG-2d0iA:undetectable | 5y7pG-2d0iA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d6f | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT E (Methanothermobacterthermautotrophicus) |
PF02637(GatB_Yqey)PF02934(GatB_N)PF02938(GAD) | 5 | LEU C 142ILE C 14ASN C 107LEU C 208GLU C 143 | None | 1.00A | 5y7pG-2d6fC:undetectable | 5y7pG-2d6fC:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d6f | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT E (Methanothermobacterthermautotrophicus) |
PF02637(GatB_Yqey)PF02934(GatB_N)PF02938(GAD) | 5 | LEU C 142ILE C 185LEU C 208LEU C 443GLU C 143 | None | 1.22A | 5y7pG-2d6fC:undetectable | 5y7pG-2d6fC:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ddx | BETA-1,3-XYLANASE (Vibrio sp. AX-4) |
no annotation | 5 | LEU A 64ASN A 23LEU A 29ALA A 26GLU A 63 | None | 1.26A | 5y7pG-2ddxA:undetectable | 5y7pG-2ddxA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dj0 | THIOREDOXIN-RELATEDTRANSMEMBRANEPROTEIN 2 (Homo sapiens) |
PF00085(Thioredoxin) | 5 | TYR A 48ASN A 61LEU A 91LEU A 93LEU A 60 | None | 1.25A | 5y7pG-2dj0A:undetectable | 5y7pG-2dj0A:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dq7 | PROTO-ONCOGENETYROSINE-PROTEINKINASE FYN (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | LEU X 66ILE X 136LEU X 131LEU X 151ALA X 152 | None | 1.08A | 5y7pG-2dq7X:undetectable | 5y7pG-2dq7X:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dut | HETEROCHROMATIN-ASSOCIATED PROTEIN MENT (Gallus gallus) |
PF00079(Serpin) | 5 | LEU A 102ILE A 193LEU A 39ALA A 40LEU A 41 | None | 1.14A | 5y7pG-2dutA:undetectable | 5y7pG-2dutA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hk5 | TYROSINE-PROTEINKINASE HCK (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | LEU A 300ILE A 370LEU A 365LEU A 385ALA A 386 | None | 1.02A | 5y7pG-2hk5A:undetectable | 5y7pG-2hk5A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i0k | OXIDOREDUCTASE (Brevibacteriumsterolicum) |
PF01565(FAD_binding_4)PF09129(Chol_subst-bind) | 5 | LEU A 612TYR A 594ILE A 597LEU A 254LEU A 197 | None | 1.04A | 5y7pG-2i0kA:undetectable | 5y7pG-2i0kA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i0k | OXIDOREDUCTASE (Brevibacteriumsterolicum) |
PF01565(FAD_binding_4)PF09129(Chol_subst-bind) | 5 | TYR A 594ILE A 597LEU A 254LEU A 197ALA A 198 | NoneNoneNoneNoneFAD A 700 (-3.3A) | 1.17A | 5y7pG-2i0kA:undetectable | 5y7pG-2i0kA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i6u | ORNITHINECARBAMOYLTRANSFERASE (Mycobacteriumtuberculosis) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | ILE A 120LEU A 300LEU A 22ALA A 23GLU A 288 | None | 1.25A | 5y7pG-2i6uA:undetectable | 5y7pG-2i6uA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ivf | ETHYLBENZENEDEHYDROGENASEALPHA-SUBUNIT (Aromatoleumaromaticum) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | LEU A 605TYR A 603ASN A 609LEU A 625GLU A 636 | NoneNoneMD1 A1987 (-3.7A)NoneMD1 A1987 (-2.9A) | 1.17A | 5y7pG-2ivfA:undetectable | 5y7pG-2ivfA:16.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vjw | GAF FAMILY PROTEIN (Mycolicibacteriumsmegmatis) |
PF01590(GAF) | 5 | LEU A 323ILE A 294LEU A 254LEU A 245ALA A 244 | None | 1.25A | 5y7pG-2vjwA:undetectable | 5y7pG-2vjwA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vpw | HYPOTHETICALMEMBRANE SPANNINGPROTEIN (Thermusthermophilus) |
PF14589(NrfD_2) | 5 | LEU C 38TYR C 49LEU C 163LEU C 176ALA C 172 | None | 1.20A | 5y7pG-2vpwC:undetectable | 5y7pG-2vpwC:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x27 | OUTER MEMBRANEPROTEIN OPRG (Pseudomonasaeruginosa) |
PF03922(OmpW) | 5 | ILE X 11ASN X 108PHE X 155LEU X 164ALA X 110 | NoneNoneC8E X1224 ( 4.7A)NoneNone | 1.19A | 5y7pG-2x27X:undetectable | 5y7pG-2x27X:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x4f | MYOSIN LIGHT CHAINKINASE FAMILY MEMBER4 (Homo sapiens) |
PF00069(Pkinase) | 5 | LEU A 163ILE A 233LEU A 228LEU A 250ALA A 251 | NoneNoneNoneEDO A1378 ( 4.6A)None | 0.96A | 5y7pG-2x4fA:undetectable | 5y7pG-2x4fA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yl2 | ACETYL-COACARBOXYLASE 1 (Homo sapiens) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 6 | ILE A 425ASN A 571LEU A 631LEU A 618ALA A 614GLU A 606 | None | 1.26A | 5y7pG-2yl2A:undetectable | 5y7pG-2yl2A:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zqq | METHYLGLUTACONYL-COAHYDRATASE (Homo sapiens) |
PF00378(ECH_1) | 5 | LEU A 107ILE A 165LEU A 184ALA A 139GLU A 76 | None | 1.16A | 5y7pG-2zqqA:undetectable | 5y7pG-2zqqA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bfn | KINESIN-LIKE PROTEINKIF22 (Homo sapiens) |
PF00225(Kinesin) | 5 | LEU A 272ILE A 215LEU A 155LEU A 157LEU A 115 | NoneNoneUNX A 708 ( 4.9A)NoneNone | 1.22A | 5y7pG-3bfnA:undetectable | 5y7pG-3bfnA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3glb | HTH-TYPETRANSCRIPTIONALREGULATOR CATM (Acinetobactersp. ADP1) |
PF03466(LysR_substrate) | 5 | ILE A 207LEU A 164ALA A 247LEU A 231GLU A 125 | None | 0.95A | 5y7pG-3glbA:undetectable | 5y7pG-3glbA:24.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hhd | FATTY ACID SYNTHASE (Homo sapiens) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ILE A 549ASN A 735LEU A 601ALA A 602LEU A 698 | None | 1.07A | 5y7pG-3hhdA:undetectable | 5y7pG-3hhdA:15.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hr8 | PROTEIN RECA (Thermotogamaritima) |
PF00154(RecA) | 5 | LEU A 128ILE A 63PHE A 219LEU A 215GLU A 125 | None | 1.22A | 5y7pG-3hr8A:undetectable | 5y7pG-3hr8A:24.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihy | PHOSPHATIDYLINOSITOL3-KINASE CATALYTICSUBUNIT TYPE 3 (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF00613(PI3Ka) | 5 | ASN A 827LEU A 766LEU A 833ALA A 832GLU A 500 | None | 1.13A | 5y7pG-3ihyA:undetectable | 5y7pG-3ihyA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m5w | TRYPTOPHANYL-TRNASYNTHETASE (Campylobacterjejuni) |
PF00579(tRNA-synt_1b) | 5 | LEU A 207ILE A 214PHE A 233LEU A 240GLU A 204 | None | 1.27A | 5y7pG-3m5wA:undetectable | 5y7pG-3m5wA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ne8 | N-ACETYLMURAMOYL-L-ALANINE AMIDASE (Bartonellahenselae) |
PF01520(Amidase_3) | 5 | LEU A 378ILE A 364ASN A 371LEU A 334GLU A 375 | None | 1.21A | 5y7pG-3ne8A:undetectable | 5y7pG-3ne8A:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qiv | SHORT-CHAINDEHYDROGENASE OR3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 5 | ILE A 182LEU A 219ALA A 24LEU A 25GLU A 230 | None | 1.22A | 5y7pG-3qivA:undetectable | 5y7pG-3qivA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r08 | MOUSE ANTI-MOUSECD3EPSILON ANTIBODY2C11 LIGHT CHAIN (Cricetulusmigratorius) |
PF07654(C1-set)PF07686(V-set) | 5 | TYR L 86ILE L 21LEU L 46LEU L 54GLU L 79 | None | 1.20A | 5y7pG-3r08L:undetectable | 5y7pG-3r08L:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r9w | GTPASE ERA (Aquifexaeolicus) |
PF01926(MMR_HSR1)PF07650(KH_2) | 5 | LEU A 279LEU A 193ALA A 194LEU A 267GLU A 278 | None | 1.17A | 5y7pG-3r9wA:undetectable | 5y7pG-3r9wA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t8l | ADENINE DEAMINASE 2 (Agrobacteriumfabrum) |
PF01979(Amidohydro_1)PF13382(Adenine_deam_C) | 5 | LEU A 277ILE A 257LEU A 241LEU A 267LEU A 314 | None | 1.26A | 5y7pG-3t8lA:undetectable | 5y7pG-3t8lA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vcy | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Aliivibriofischeri) |
PF00275(EPSP_synthase) | 5 | LEU A 371TYR A 400ILE A 403LEU A 313ALA A 309 | None | 1.21A | 5y7pG-3vcyA:undetectable | 5y7pG-3vcyA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zef | PRE-MRNA-SPLICINGFACTOR 8 (Saccharomycescerevisiae) |
PF08084(PROCT)PF10596(U6-snRNA_bdg)PF10597(U5_2-snRNA_bdg)PF10598(RRM_4)PF12134(PRP8_domainIV) | 5 | LEU B1066ILE B1078LEU B 999ALA B1110LEU B1107 | None | 1.20A | 5y7pG-3zefB:undetectable | 5y7pG-3zefB:12.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zxu | MCM21CTF19 (Kluyveromyceslactis;Kluyveromyceslactis) |
PF09496(CENP-O)no annotation | 5 | LEU A 139ILE A 180LEU A 169LEU B 80GLU A 140 | None | 1.15A | 5y7pG-3zxuA:undetectable | 5y7pG-3zxuA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4btg | MAJOR INNER PROTEINP1 (Pseudomonasvirus phi6) |
no annotation | 5 | LEU A 333ILE A 322LEU A 284LEU A 288ALA A 289 | None | 1.20A | 5y7pG-4btgA:undetectable | 5y7pG-4btgA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4czb | NA(+)/H(+)ANTIPORTER 1 (Methanocaldococcusjannaschii) |
PF00999(Na_H_Exchanger) | 5 | ILE A 209LEU A 221LEU A 223ALA A 226LEU A 71 | None | 1.21A | 5y7pG-4czbA:undetectable | 5y7pG-4czbA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e7w | GLYCOGEN SYNTHASEKINASE 3 (Ustilago maydis) |
PF00069(Pkinase) | 5 | ILE A 163LEU A 150LEU A 316ALA A 315LEU A 297 | None | 1.22A | 5y7pG-4e7wA:undetectable | 5y7pG-4e7wA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ep6 | CYTOCHROME P450-LIKEPROTEIN XPLA (Rhodococcusrhodochrous) |
PF00067(p450) | 5 | PHE A 388LEU A 363ALA A 364LEU A 306GLU A 353 | HEM A 601 (-4.2A)NoneNoneNoneNone | 1.17A | 5y7pG-4ep6A:undetectable | 5y7pG-4ep6A:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4evf | GIARDIN SUBUNITALPHA-1 (Giardiaintestinalis) |
PF00191(Annexin) | 5 | LEU A 58ILE A 287PHE A 25ALA A 14LEU A 11 | None | 1.21A | 5y7pG-4evfA:undetectable | 5y7pG-4evfA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gis | ENOLASE (Vibrio harveyi) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 143LEU A 203ALA A 127LEU A 135GLU A 144 | None | 1.14A | 5y7pG-4gisA:undetectable | 5y7pG-4gisA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl0 | LMO0810 PROTEIN (Listeriamonocytogenes) |
PF13416(SBP_bac_8) | 5 | TYR A 344PHE A 349LEU A 206ALA A 202LEU A 184 | PG4 A 503 (-3.7A)NoneNoneNoneNone | 1.17A | 5y7pG-4gl0A:undetectable | 5y7pG-4gl0A:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gve | NUCLEOPROTEIN (Tacaribemammarenavirus) |
PF17290(Arena_ncap_C) | 5 | LEU A 467ILE A 456LEU A 399LEU A 533ALA A 532 | None | 1.26A | 5y7pG-4gveA:undetectable | 5y7pG-4gveA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l69 | RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE E (Mycobacteriumtuberculosis) |
PF04452(Methyltrans_RNA) | 5 | LEU A 212PHE A 106LEU A 107LEU A 85ALA A 84 | None | 1.21A | 5y7pG-4l69A:undetectable | 5y7pG-4l69A:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ll8 | MYOSIN-4 (Saccharomycescerevisiae) |
PF01843(DIL) | 5 | LEU A1363ILE A1335LEU A1312LEU A1432LEU A1383 | None | 0.83A | 5y7pG-4ll8A:undetectable | 5y7pG-4ll8A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mf6 | GLUTATHIONES-TRANSFERASE DOMAIN (Paraburkholderiagraminis) |
PF00043(GST_C)PF02798(GST_N) | 5 | ILE A 126PHE A 208LEU A 164ALA A 214GLU A 40 | None | 1.21A | 5y7pG-4mf6A:undetectable | 5y7pG-4mf6A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mn6 | SENSOR PROTEINKINASE WALK (Staphylococcusaureus) |
PF13426(PAS_9) | 5 | LEU A 314ILE A 277ALA A 342LEU A 334GLU A 317 | None | 1.23A | 5y7pG-4mn6A:undetectable | 5y7pG-4mn6A:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pyr | PUTATIVEBRANCHED-CHAIN AMINOACID ABC TRANSPORTER (Chromobacteriumviolaceum) |
PF04348(LppC) | 5 | LEU A 90ILE A 154LEU A 342ALA A 339LEU A 335 | NoneNoneNoneNoneGSH A 401 (-4.8A) | 1.15A | 5y7pG-4pyrA:undetectable | 5y7pG-4pyrA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7u | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Vibrio cholerae) |
PF00275(EPSP_synthase) | 5 | LEU A 371TYR A 400ILE A 403LEU A 313ALA A 309 | None | 1.20A | 5y7pG-4r7uA:undetectable | 5y7pG-4r7uA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rk1 | RIBOSETRANSCRIPTIONALREGULATOR (Enterococcusfaecium) |
PF13377(Peripla_BP_3) | 5 | LEU A 262LEU A 223LEU A 250ALA A 249GLU A 263 | None | 1.26A | 5y7pG-4rk1A:undetectable | 5y7pG-4rk1A:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wuv | 2-HYDROXYCYCLOHEXANECARBOXYL-COADEHYDROGENASE (Haemophilusinfluenzae) |
PF00106(adh_short) | 5 | LEU A 253ILE A 260LEU A 13ALA A 9GLU A 250 | None | 1.16A | 5y7pG-4wuvA:undetectable | 5y7pG-4wuvA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z9n | AMINO ACID ABCTRANSPORTER,PERIPLASMIC AMINOACID-BINDING PROTEIN (Brucella ovis) |
PF00497(SBP_bac_3) | 5 | TYR A 174LEU A 181LEU A 186ALA A 187GLU A 161 | None | 1.26A | 5y7pG-4z9nA:undetectable | 5y7pG-4z9nA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zbz | URACIL-DNAGLYCOSYLASE (Sulfurisphaeratokodaii) |
PF03167(UDG) | 5 | LEU A 73ILE A 117LEU A 178LEU A 63GLU A 74 | GOL A 203 ( 4.7A)NoneNoneNoneNone | 1.08A | 5y7pG-4zbzA:undetectable | 5y7pG-4zbzA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zms | RESPONSE REGULATOR (Streptococcuspneumoniae) |
PF00072(Response_reg)PF00196(GerE) | 5 | ILE A 159ASN A 185LEU A 181ALA A 189LEU A 178 | None | 1.25A | 5y7pG-4zmsA:undetectable | 5y7pG-4zmsA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bn7 | MALTODEXTRINGLUCOSIDASE (Escherichiacoli) |
PF00128(Alpha-amylase) | 5 | ILE A 409LEU A 455LEU A 463ALA A 466LEU A 470 | None | 1.12A | 5y7pG-5bn7A:undetectable | 5y7pG-5bn7A:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cth | BIDIRECTIONAL SUGARTRANSPORTER SWEET2B (Oryza sativa) |
PF03083(MtN3_slv) | 5 | LEU A 143PHE A 83LEU A 21ALA A 20LEU A 23 | None | 1.27A | 5y7pG-5cthA:undetectable | 5y7pG-5cthA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dji | 3'-PHOSPHOADENOSINE5'-PHOSPHATEPHOSPHATASE (Mycobacteriumtuberculosis) |
PF00459(Inositol_P) | 5 | ILE A 111ASN A 238LEU A 61ALA A 69GLU A 123 | None | 1.19A | 5y7pG-5djiA:undetectable | 5y7pG-5djiA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5do8 | LMO0184 PROTEIN (Listeriamonocytogenes) |
no annotation | 5 | ILE B 520PHE B 491LEU B 484LEU B 300ALA B 489 | None | 1.14A | 5y7pG-5do8B:undetectable | 5y7pG-5do8B:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ej1 | PUTATIVE CELLULOSESYNTHASE (Rhodobactersphaeroides) |
PF03170(BcsB) | 5 | LEU B 200ILE B 270LEU B 298ALA B 229LEU B 226 | None | 1.07A | 5y7pG-5ej1B:undetectable | 5y7pG-5ej1B:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fhz | ALDEHYDEDEHYDROGENASE FAMILY1 MEMBER A3 (Homo sapiens) |
PF00171(Aldedh) | 5 | ILE A 232ASN A 199LEU A 187ALA A 194LEU A 195 | None | 1.18A | 5y7pG-5fhzA:undetectable | 5y7pG-5fhzA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gr8 | LEUCINE-RICH REPEATRECEPTOR-LIKEPROTEIN KINASE PEPR1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | LEU A 231ILE A 215ASN A 277LEU A 224LEU A 274 | None | 1.21A | 5y7pG-5gr8A:undetectable | 5y7pG-5gr8A:19.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gs7 | CHOLOYLGLYCINEHYDROLASE (Enterococcusfaecalis) |
PF02275(CBAH) | 6 | ASN A 79PHE A 99LEU A 133LEU A 135LEU A 138GLU A 269 | None | 0.69A | 5y7pG-5gs7A:48.6 | 5y7pG-5gs7A:53.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gs7 | CHOLOYLGLYCINEHYDROLASE (Enterococcusfaecalis) |
PF02275(CBAH) | 6 | ILE A 58ASN A 79PHE A 99LEU A 135LEU A 138GLU A 269 | None | 1.05A | 5y7pG-5gs7A:48.6 | 5y7pG-5gs7A:53.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5gs7 | CHOLOYLGLYCINEHYDROLASE (Enterococcusfaecalis) |
PF02275(CBAH) | 6 | TYR A 24ILE A 58ASN A 79LEU A 135LEU A 138GLU A 269 | None | 1.00A | 5y7pG-5gs7A:48.6 | 5y7pG-5gs7A:53.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h2v | IMPORTIN SUBUNITBETA-3 (Saccharomycescerevisiae) |
PF13513(HEAT_EZ) | 5 | ILE A 727LEU A 754ALA A 750LEU A 706GLU A 742 | None | 1.25A | 5y7pG-5h2vA:undetectable | 5y7pG-5h2vA:14.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hke | BILE SALT HYDROLASE (Lactobacillussalivarius) |
PF02275(CBAH) | 7 | ASN A 79PHE A 100LEU A 134LEU A 136ALA A 137LEU A 139GLU A 270 | OCS A 2 ( 3.7A)NoneNoneNoneNoneNoneNone | 0.76A | 5y7pG-5hkeA:52.5 | 5y7pG-5hkeA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hke | BILE SALT HYDROLASE (Lactobacillussalivarius) |
PF02275(CBAH) | 7 | LEU A 18ASN A 79PHE A 100LEU A 134LEU A 136ALA A 137LEU A 139 | OCS A 2 ( 3.9A)OCS A 2 ( 3.7A)NoneNoneNoneNoneNone | 1.35A | 5y7pG-5hkeA:52.5 | 5y7pG-5hkeA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hke | BILE SALT HYDROLASE (Lactobacillussalivarius) |
PF02275(CBAH) | 8 | LEU A 18TYR A 24ILE A 56PHE A 100LEU A 134LEU A 136ALA A 137LEU A 139 | OCS A 2 ( 3.9A)NoneNoneNoneNoneNoneNoneNone | 1.37A | 5y7pG-5hkeA:52.5 | 5y7pG-5hkeA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hke | BILE SALT HYDROLASE (Lactobacillussalivarius) |
PF02275(CBAH) | 9 | LEU A 20TYR A 24ILE A 56PHE A 100LEU A 134LEU A 136ALA A 137LEU A 139GLU A 270 | None | 0.51A | 5y7pG-5hkeA:52.5 | 5y7pG-5hkeA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hop | LMO0182 PROTEIN (Listeriamonocytogenes) |
no annotation | 5 | PHE A 234LEU A 196ALA A 192LEU A 211GLU A 218 | None | 1.25A | 5y7pG-5hopA:undetectable | 5y7pG-5hopA:25.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikz | OXALATE BIOSYNTHETICCOMPONENT 1 (Burkholderiathailandensis) |
PF05853(BKACE) | 5 | ASN A 91LEU A 35ALA A 30LEU A 88GLU A 63 | None | 1.09A | 5y7pG-5ikzA:undetectable | 5y7pG-5ikzA:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jnm | MANNITOL-1-PHOSPHATE5-DEHYDROGENASE (Staphylococcusaureus) |
no annotation | 5 | LEU A 356ILE A 289LEU A 320LEU A 367ALA A 363 | None | 1.10A | 5y7pG-5jnmA:undetectable | 5y7pG-5jnmA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ko3 | ORF1A (Middle Eastrespiratorysyndrome-relatedcoronavirus) |
PF08715(Viral_protease) | 5 | LEU A 68TYR A 72ILE A 130LEU A 151LEU A 86 | NoneNoneNoneACT A 405 ( 4.5A)None | 1.21A | 5y7pG-5ko3A:undetectable | 5y7pG-5ko3A:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l1t | PENTALENOLACTONESYNTHASE (Streptomycesarenae) |
PF00067(p450) | 5 | ILE A 272LEU A 248LEU A 371LEU A 140GLU A 117 | None | 1.25A | 5y7pG-5l1tA:undetectable | 5y7pG-5l1tA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ode | GLL2934 PROTEIN (Gloeobacterviolaceus) |
no annotation | 5 | LEU A 57ILE A 71LEU A 28LEU A 284ALA A 297 | FAD A 400 (-4.6A)NoneNoneNoneFAD A 400 ( 3.5A) | 1.27A | 5y7pG-5odeA:undetectable | 5y7pG-5odeA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uyr | BACTERIOPHYTOCHROME (Xanthomonascampestris) |
no annotation | 5 | LEU A 187TYR A 190ILE A 178LEU A 256GLU A 186 | NoneBLA A 900 (-4.4A)NoneNoneNone | 1.23A | 5y7pG-5uyrA:undetectable | 5y7pG-5uyrA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uze | INOSINE-5'-MONOPHOSPHATEDEHYDROGENASE,INOSINE-5'-MONOPHOSPHATEDEHYDROGENASE (Clostridiumperfringens) |
PF00478(IMPDH) | 5 | ILE A 434ASN A 19LEU A 349ALA A 453GLU A 22 | None | 1.06A | 5y7pG-5uzeA:undetectable | 5y7pG-5uzeA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5va8 | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Paraburkholderiaphymatum) |
PF13561(adh_short_C2) | 5 | LEU A 44ILE A 66LEU A 11LEU A 27ALA A 24 | NoneNAP A 301 (-4.2A)NoneNoneNone | 1.12A | 5y7pG-5va8A:undetectable | 5y7pG-5va8A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vjc | PROTEIN MINISPINDLES (Drosophilamelanogaster) |
no annotation | 5 | LEU A1218TYR A1254ILE A1211LEU A1236LEU A1231 | None | 1.22A | 5y7pG-5vjcA:undetectable | 5y7pG-5vjcA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wdi | UBIQUITIN-ASSOCIATEDAND SH3DOMAIN-CONTAININGPROTEIN A (Homo sapiens) |
PF00300(His_Phos_1) | 5 | PHE A 447LEU A 484ALA A 483LEU A 526GLU A 556 | None | 1.25A | 5y7pG-5wdiA:undetectable | 5y7pG-5wdiA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x0y | TRANSCRIPTIONREGULATORY PROTEINSNF2 (Saccharomycescerevisiae) |
PF00176(SNF2_N)PF00271(Helicase_C)PF14619(SnAC) | 5 | LEU O 683ILE O 945ASN O 784LEU O 987LEU O 781 | None | 1.17A | 5y7pG-5x0yO:undetectable | 5y7pG-5x0yO:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yy0 | CYTOSOLICNIFE-HYDROGENASE,ALPHA SUBUNIT (Thermococcuskodakarensis) |
no annotation | 5 | LEU A 189ILE A 101LEU A 283ALA A 287LEU A 312 | None | 1.25A | 5y7pG-5yy0A:undetectable | 5y7pG-5yy0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bk6 | HENDRA VIRUS MATRIXPROTEIN (Hendrahenipavirus) |
no annotation | 5 | LEU A 194ILE A 278LEU A 206LEU A 327ALA A 203 | NoneNoneNoneCME A 255 ( 4.7A)None | 1.14A | 5y7pG-6bk6A:undetectable | 5y7pG-6bk6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c4n | PSEUDOPALINEDEHYDROGENASE (Pseudomonasaeruginosa) |
no annotation | 5 | LEU A 121LEU A 108ALA A 135LEU A 102GLU A 210 | None | 1.26A | 5y7pG-6c4nA:undetectable | 5y7pG-6c4nA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d5i | PHOSPHOENOLPYRUVATECARBOXYKINASE (ATP) (Escherichiacoli) |
no annotation | 5 | LEU A 486ILE A 459PHE A 359LEU A 374GLU A 485 | None | 1.25A | 5y7pG-6d5iA:undetectable | 5y7pG-6d5iA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 9atc | ASPARTATETRANSCARBAMOYLASE (Escherichiacoli) |
PF01948(PyrI)PF02748(PyrI_C) | 5 | ILE B 21ASN B 153LEU B 74LEU B 76LEU B 151 | None | 1.23A | 5y7pG-9atcB:undetectable | 5y7pG-9atcB:18.94 |