SIMILAR PATTERNS OF AMINO ACIDS FOR 5Y2T_A_8LXA501_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1chm CREATINE
AMIDINOHYDROLASE

(Pseudomonas
putida) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		3 SER A 356
HIS A 324
TYR A 258
 None
CMS  A 404 (-4.5A)
None
 0.92A 5y2tA-1chmA:
0.0		 5y2tA-1chmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1elp GAMMA-D CRYSTALLIN

(Bos taurus) 		PF00030
(Crystall) 		3 SER A  20
HIS A  22
TYR A  16
 None
 0.89A 5y2tA-1elpA:
undetectable		 5y2tA-1elpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR

(Homo sapiens) 		PF00079
(Serpin) 		3 SER A  73
HIS A  99
TYR A 142
 None
 1.02A 5y2tA-1imvA:
0.0		 5y2tA-1imvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kp0 CREATINE
AMIDINOHYDROLASE

(Actinobacillus) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		3 SER A 355
HIS A 323
TYR A 257
 None
 0.90A 5y2tA-1kp0A:
0.0		 5y2tA-1kp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kwm PROCARBOXYPEPTIDASE
B

(Homo sapiens) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		3 SER A 131
HIS A 133
TYR A 165
 None
 1.04A 5y2tA-1kwmA:
0.0		 5y2tA-1kwmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)

(Tobacco etch
virus) 		PF00863
(Peptidase_C4) 		3 SER A 135
HIS A 214
TYR A 178
 None
 0.94A 5y2tA-1lvmA:
undetectable		 5y2tA-1lvmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m8u GAMMA-E

(Bos taurus) 		PF00030
(Crystall) 		3 SER A  20
HIS A  22
TYR A  16
 None
 0.92A 5y2tA-1m8uA:
undetectable		 5y2tA-1m8uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mjt NITRIC-OXIDE
SYNTHASE HOMOLOG

(Staphylococcus
aureus) 		PF02898
(NO_synthase) 		3 SER A 327
HIS A 331
TYR A 333
 None
SUC  A 601 ( 3.9A)
SUC  A 601 (-4.1A)
 0.83A 5y2tA-1mjtA:
0.4		 5y2tA-1mjtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vke CARBOXYMUCONOLACTONE
DECARBOXYLASE FAMILY
PROTEIN

(Thermotoga
maritima) 		PF02627
(CMD) 		3 SER A  54
HIS A  66
TYR A  36
 UNL  A 123 ( 3.8A)
UNL  A 123 (-4.3A)
UNL  A 123 (-4.4A)
 1.02A 5y2tA-1vkeA:
undetectable		 5y2tA-1vkeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w6j LANOSTEROL SYNTHASE

(Homo sapiens) 		PF13243
(SQHop_cyclase_C)
PF13249
(SQHop_cyclase_N) 		3 SER A 191
HIS A 289
TYR A 297
 None
 1.02A 5y2tA-1w6jA:
0.1		 5y2tA-1w6jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xr4 PUTATIVE CITRATE
LYASE ALPHA
CHAIN/CITRATE-ACP
TRANSFERASE

(Salmonella
enterica) 		PF04223
(CitF) 		3 SER A 118
HIS A  65
TYR A 186
 None
 0.89A 5y2tA-1xr4A:
0.0		 5y2tA-1xr4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xrc S-ADENOSYLMETHIONINE
SYNTHETASE

(Escherichia
coli) 		PF00438
(S-AdoMet_synt_N)
PF02772
(S-AdoMet_synt_M)
PF02773
(S-AdoMet_synt_C) 		3 SER A 263
HIS A 359
TYR A 276
 None
 1.05A 5y2tA-1xrcA:
0.0		 5y2tA-1xrcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ybe NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE

(Agrobacterium
tumefaciens) 		PF04095
(NAPRTase) 		3 SER A 160
HIS A 207
TYR A 176
 None
 0.86A 5y2tA-1ybeA:
undetectable		 5y2tA-1ybeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yxa SERINE (OR CYSTEINE)
PROTEINASE
INHIBITOR, CLADE A,
MEMBER 3N

(Mus musculus) 		PF00079
(Serpin) 		3 SER A  86
HIS A 114
TYR A 159
 None
 1.02A 5y2tA-1yxaA:
undetectable		 5y2tA-1yxaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1x PHYTANOYL-COA
DIOXYGENASE

(Homo sapiens) 		PF05721
(PhyH) 		3 SER A 186
HIS A 259
TYR A  46
 None
 1.04A 5y2tA-2a1xA:
undetectable		 5y2tA-2a1xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5u COLICIN E3

(Escherichia
coli) 		PF03515
(Cloacin)
PF09000
(Cytotoxic)
PF11570
(E2R135) 		3 SER A 529
HIS A 526
TYR A 519
 None
 1.05A 5y2tA-2b5uA:
undetectable		 5y2tA-2b5uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1i PEPTIDOGLYCAN GLCNAC
DEACETYLASE

(Streptococcus
pneumoniae) 		PF01522
(Polysacc_deac_1) 		3 SER A 327
HIS A 330
TYR A 367
 None
ZN  A1465 ( 3.2A)
SO4  A1467 ( 4.3A)
 1.02A 5y2tA-2c1iA:
undetectable		 5y2tA-2c1iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ca4 SULFITE:CYTOCHROME C
OXIDOREDUCTASE
SUBUNIT A

(Starkeya
novella) 		PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer) 		3 SER A 173
HIS A 176
TYR A 208
 None
 0.93A 5y2tA-2ca4A:
undetectable		 5y2tA-2ca4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cc0 ACETYL-XYLAN
ESTERASE

(Streptomyces
lividans) 		PF01522
(Polysacc_deac_1) 		3 SER A  63
HIS A  66
TYR A 103
 None
ZN  A 200 ( 3.3A)
ACT  A 201 (-4.9A)
 1.01A 5y2tA-2cc0A:
undetectable		 5y2tA-2cc0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cdu NADPH OXIDASE

(Lactobacillus
sanfranciscensis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		3 SER A  41
HIS A  10
TYR A  62
 FAD  A 500 (-4.5A)
CSX  A  42 (-3.6A)
None
 0.97A 5y2tA-2cduA:
undetectable		 5y2tA-2cduA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cy8 D-PHENYLGLYCINE
AMINOTRANSFERASE

(Pseudomonas
stutzeri) 		PF00202
(Aminotran_3) 		3 SER A  14
HIS A  39
TYR A   7
 None
 0.91A 5y2tA-2cy8A:
undetectable		 5y2tA-2cy8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ddt SPHINGOMYELIN
PHOSPHODIESTERASE

(Bacillus cereus) 		PF03372
(Exo_endo_phos) 		3 SER A 294
HIS A  15
TYR A  42
 None
None
SO4  A 312 (-4.8A)
 1.00A 5y2tA-2ddtA:
undetectable		 5y2tA-2ddtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE

(Sulfurisphaera
tokodaii) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 SER A 161
HIS A 336
TYR A  81
 None
 1.00A 5y2tA-2f7lA:
undetectable		 5y2tA-2f7lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hi9 PLASMA SERINE
PROTEASE INHIBITOR

(Homo sapiens) 		PF00079
(Serpin) 		3 SER A  61
HIS A  89
TYR A 134
 None
 1.03A 5y2tA-2hi9A:
undetectable		 5y2tA-2hi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hj0 PUTATIVE CITRATE
LYASE, ALFA SUBUNIT

(Streptococcus
mutans) 		PF04223
(CitF) 		3 SER A 124
HIS A  71
TYR A 192
 CIT  A 601 (-2.8A)
CIT  A 601 (-3.8A)
None
 0.95A 5y2tA-2hj0A:
undetectable		 5y2tA-2hj0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hk0 D-PSICOSE
3-EPIMERASE

(Agrobacterium
tumefaciens) 		PF01261
(AP_endonuc_2) 		3 SER A 110
HIS A 158
TYR A 116
 SER  A 110 ( 0.0A)
HIS  A 158 ( 1.0A)
TYR  A 116 ( 1.3A)
 1.04A 5y2tA-2hk0A:
undetectable		 5y2tA-2hk0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r17 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 35

(Homo sapiens) 		PF03635
(Vps35) 		3 SER C 679
HIS C 675
TYR C 729
 None
 1.01A 5y2tA-2r17C:
undetectable		 5y2tA-2r17C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r55 STAR-RELATED LIPID
TRANSFER PROTEIN 5

(Homo sapiens) 		PF01852
(START) 		3 SER A  43
HIS A 177
TYR A  20
 None
 1.02A 5y2tA-2r55A:
undetectable		 5y2tA-2r55A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vrk ALPHA-L-ARABINOFURAN
OSIDASE

(Thermobacillus
xylanilyticus) 		PF06964
(Alpha-L-AF_C) 		3 SER A 417
HIS A 334
TYR A  23
 None
 0.95A 5y2tA-2vrkA:
undetectable		 5y2tA-2vrkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a05 TRYPTOPHANYL-TRNA
SYNTHETASE

(Aeropyrum
pernix) 		PF00579
(tRNA-synt_1b) 		3 SER A 259
HIS A  87
TYR A 132
 None
 1.02A 5y2tA-3a05A:
undetectable		 5y2tA-3a05A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3azq AMINOPEPTIDASE

(Streptomyces
morookaense) 		PF00326
(Peptidase_S9) 		3 SER A 436
HIS A 431
TYR A 461
 None
 1.05A 5y2tA-3azqA:
undetectable		 5y2tA-3azqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b0q PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo sapiens) 		PF00104
(Hormone_recep) 		3 SER A 289
HIS A 323
TYR A 473
 MC5  A   1 (-2.6A)
MC5  A   1 (-3.8A)
MC5  A   1 (-4.9A)
 0.34A 5y2tA-3b0qA:
40.2		 5y2tA-3b0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Bacillus
anthracis) 		PF02350
(Epimerase_2) 		3 SER A 346
HIS A 342
TYR A 280
 None
 0.99A 5y2tA-3beoA:
undetectable		 5y2tA-3beoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dme CONSERVED EXPORTED
PROTEIN

(Bordetella
pertussis) 		PF01266
(DAO) 		3 SER A 350
HIS A  52
TYR A 248
 TLA  A 999 ( 2.6A)
TLA  A 999 ( 3.7A)
TLA  A 999 (-4.7A)
 0.96A 5y2tA-3dmeA:
undetectable		 5y2tA-3dmeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dy5 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN

(Plexaura
homomalla) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 SER A 940
HIS A 789
TYR A1013
 None
 0.92A 5y2tA-3dy5A:
undetectable		 5y2tA-3dy5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3en8 UNCHARACTERIZED
NTF-2 LIKE PROTEIN

(Paraburkholderia
xenovorans) 		PF12680
(SnoaL_2) 		3 SER A  17
HIS A  13
TYR A  29
 None
 0.91A 5y2tA-3en8A:
undetectable		 5y2tA-3en8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fg4 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN

(Plexaura
homomalla) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 SER A 940
HIS A 789
TYR A1013
 None
 0.96A 5y2tA-3fg4A:
undetectable		 5y2tA-3fg4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g1z PUTATIVE LYSYL-TRNA
SYNTHETASE

(Salmonella
enterica) 		PF00152
(tRNA-synt_2) 		3 SER A 226
HIS A 214
TYR A 125
 PO4  A 327 (-2.7A)
PO4  A 327 (-3.8A)
PO4  A 327 (-4.7A)
 0.98A 5y2tA-3g1zA:
undetectable		 5y2tA-3g1zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I

(Cytophaga
hutchinsonii) 		PF00425
(Chorismate_bind) 		3 SER A  12
HIS A  48
TYR A  32
 None
 0.69A 5y2tA-3h9mA:
undetectable		 5y2tA-3h9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihm STYRENE
MONOOXYGENASE A

(Pseudomonas
putida) 		no annotation 3 SER A 312
HIS A  50
TYR A 104
 None
 0.75A 5y2tA-3ihmA:
undetectable		 5y2tA-3ihmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iup PUTATIVE
NADPH:QUINONE
OXIDOREDUCTASE

(Cupriavidus
pinatubonensis) 		no annotation 3 SER A 181
HIS A 176
TYR A 285
 NDP  A 401 (-3.5A)
None
NDP  A 401 (-4.0A)
 0.87A 5y2tA-3iupA:
undetectable		 5y2tA-3iupA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k96 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
[NAD(P)+]

(Coxiella
burnetii) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		3 SER A  35
HIS A  40
TYR A  53
 None
 0.96A 5y2tA-3k96A:
undetectable		 5y2tA-3k96A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ki6 CHOLIX TOXIN

(Vibrio cholerae) 		PF09009
(Exotox-A_cataly) 		3 SER A 621
HIS A 446
TYR A 532
 None
 1.00A 5y2tA-3ki6A:
undetectable		 5y2tA-3ki6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lm6 STAGE V SPORULATION
PROTEIN AD

(Bacillus
subtilis) 		PF07451
(SpoVAD) 		3 SER A 184
HIS A 216
TYR A 227
 None
 0.71A 5y2tA-3lm6A:
undetectable		 5y2tA-3lm6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lma STAGE V SPORULATION
PROTEIN AD (SPOVAD)

(Bacillus
licheniformis) 		PF07451
(SpoVAD) 		3 SER A 184
HIS A 216
TYR A 227
 None
 0.67A 5y2tA-3lmaA:
undetectable		 5y2tA-3lmaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q9o EXOTOXIN A

(Vibrio cholerae) 		PF09009
(Exotox-A_cataly)
PF09101
(Exotox-A_bind)
PF09102
(Exotox-A_target) 		3 SER A 621
HIS A 446
TYR A 532
 None
 1.00A 5y2tA-3q9oA:
undetectable		 5y2tA-3q9oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfz APOPTOTIC PEPTIDASE
ACTIVATING FACTOR 1

(Mus musculus) 		PF00400
(WD40)
PF00931
(NB-ARC)
PF12894
(ANAPC4_WD40) 		3 SER A1195
HIS A1177
TYR A1199
 None
 0.95A 5y2tA-3sfzA:
undetectable		 5y2tA-3sfzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tih HIV-1 CLADE C
ZM109F.PB4 GP120

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		3 SER A 264
HIS A 287
TYR A 484
 None
 0.99A 5y2tA-3tihA:
undetectable		 5y2tA-3tihA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u7g BIFUNCTIONAL
POLYNUCLEOTIDE
PHOSPHATASE/KINASE

(Mus musculus) 		PF08645
(PNK3P)
PF13671
(AAA_33) 		3 SER A 520
HIS A 458
TYR A 516
 GOL  A   1 (-2.4A)
GOL  A   1 (-3.4A)
None
 1.04A 5y2tA-3u7gA:
undetectable		 5y2tA-3u7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v98 ARACHIDONATE
5-LIPOXYGENASE

(Homo sapiens) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 SER A 547
HIS A 399
TYR A 620
 None
 0.98A 5y2tA-3v98A:
undetectable		 5y2tA-3v98A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vf1 11R-LIPOXYGENASE

(Gersemia
fruticosa) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 SER A 553
HIS A 405
TYR A 626
 None
 0.92A 5y2tA-3vf1A:
undetectable		 5y2tA-3vf1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE

(Vibrio
parahaemolyticus) 		PF01522
(Polysacc_deac_1) 		3 SER A  94
HIS A  97
TYR A 165
 None
ZN  A 902 ( 3.3A)
None
 0.98A 5y2tA-3wx7A:
undetectable		 5y2tA-3wx7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4au2 SERPIN PEPTIDASE
INHIBITOR, CLADE H
(HEAT SHOCK PROTEIN
47), MEMBER 1,
(COLLAGEN BINDING
PROTEIN 1)

(Canis lupus) 		PF00079
(Serpin) 		3 SER A  82
HIS A 108
TYR A 154
 None
 0.94A 5y2tA-4au2A:
undetectable		 5y2tA-4au2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4axs CARBAMATE KINASE

(Mycoplasma
penetrans) 		PF00696
(AA_kinase) 		3 SER A  80
HIS A  45
TYR A 107
 None
 0.98A 5y2tA-4axsA:
undetectable		 5y2tA-4axsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bc7 ALKYLDIHYDROXYACETON
EPHOSPHATE SYNTHASE,
PEROXISOMAL

(Cavia porcellus) 		PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C) 		3 SER A 319
HIS A 615
TYR A 571
 None
None
SO4  A1659 (-4.7A)
 0.97A 5y2tA-4bc7A:
undetectable		 5y2tA-4bc7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c41 CORTICOSTEROID-BINDI
NG GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		3 SER A  56
HIS A  84
TYR A 129
 None
 0.97A 5y2tA-4c41A:
undetectable		 5y2tA-4c41A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ce5 AT-OMEGATA

(Aspergillus
terreus) 		PF01063
(Aminotran_4) 		3 SER A  64
HIS A 310
TYR A 306
 None
 0.99A 5y2tA-4ce5A:
undetectable		 5y2tA-4ce5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cmf AMINOTRANSFERASE

([Nectria]
haematococca) 		PF01063
(Aminotran_4) 		3 SER A  62
HIS A 309
TYR A 305
 None
 0.97A 5y2tA-4cmfA:
undetectable		 5y2tA-4cmfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e9o IMV MEMBRANE PROTEIN

(Vaccinia virus) 		PF00194
(Carb_anhydrase) 		3 SER X 118
HIS X  80
TYR X 169
 None
 0.98A 5y2tA-4e9oX:
undetectable		 5y2tA-4e9oX:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4efc ADENYLOSUCCINATE
LYASE

(Trypanosoma
brucei) 		PF00206
(Lyase_1)
PF08328
(ASL_C) 		3 SER A 332
HIS A 280
TYR A 158
 None
 1.05A 5y2tA-4efcA:
undetectable		 5y2tA-4efcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ft2 DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Zea mays) 		PF00145
(DNA_methylase)
PF00385
(Chromo)
PF01426
(BAH) 		3 SER A 309
HIS A 273
TYR A 294
 None
 0.92A 5y2tA-4ft2A:
undetectable		 5y2tA-4ft2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ft2 DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Zea mays) 		PF00145
(DNA_methylase)
PF00385
(Chromo)
PF01426
(BAH) 		3 SER A 354
HIS A 388
TYR A 836
 None
 0.86A 5y2tA-4ft2A:
undetectable		 5y2tA-4ft2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ftd UNCHARACTERIZED
PROTEIN

(Bacteroides
eggerthii) 		PF15416
(DUF4623) 		3 SER A 173
HIS A 184
TYR A 151
 None
 0.96A 5y2tA-4ftdA:
undetectable		 5y2tA-4ftdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iox TRIPARTITE TERMINASE
SUBUNIT UL15

(Human
alphaherpesvirus
1) 		PF02499
(DNA_pack_C) 		3 SER A 705
HIS A 540
TYR A 676
 None
 0.95A 5y2tA-4ioxA:
undetectable		 5y2tA-4ioxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jgf GAMMA-CRYSTALLIN D

(Homo sapiens) 		PF00030
(Crystall) 		3 SER A  20
HIS A  22
TYR A  16
 None
 0.93A 5y2tA-4jgfA:
undetectable		 5y2tA-4jgfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkm BETA-GLUCURONIDASE

(Clostridium
perfringens) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		3 SER A 417
HIS A 360
TYR A 446
 None
 0.99A 5y2tA-4jkmA:
undetectable		 5y2tA-4jkmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqb PROTEIN H03A11.1

(Caenorhabditis
elegans) 		PF06702
(Fam20C) 		3 SER A 439
HIS A 435
TYR A 449
 None
 1.03A 5y2tA-4kqbA:
undetectable		 5y2tA-4kqbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m0m PUTATIVE
UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		no annotation 3 SER A 324
HIS A 212
TYR A 447
 PO4  A 804 (-2.9A)
PO4  A 804 (-3.8A)
None
 0.94A 5y2tA-4m0mA:
undetectable		 5y2tA-4m0mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nre ARACHIDONATE
15-LIPOXYGENASE B

(Homo sapiens) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 SER A 550
HIS A 405
TYR A 623
 None
 0.97A 5y2tA-4nreA:
undetectable		 5y2tA-4nreA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nz5 DEACETYLASE DA1

(Vibrio cholerae) 		PF01522
(Polysacc_deac_1) 		3 SER A  98
HIS A 101
TYR A 169
 None
NDG  A 504 ( 3.4A)
None
 0.96A 5y2tA-4nz5A:
undetectable		 5y2tA-4nz5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o0m CIRCADIAN CLOCK
PROTEIN KINASE KAIC

(Thermosynechococcus
elongatus) 		PF06745
(ATPase) 		3 SER A 353
HIS A 359
TYR A 317
 None
 1.02A 5y2tA-4o0mA:
undetectable		 5y2tA-4o0mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pd4 CYTOCHROME B

(Saccharomyces
cerevisiae) 		PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B) 		3 SER C 170
HIS C 141
TYR C 136
 None
 1.03A 5y2tA-4pd4C:
undetectable		 5y2tA-4pd4C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uph SULFATASE (SULFURIC
ESTER HYDROLASE)
PROTEIN

(Agrobacterium
tumefaciens) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		3 SER A  22
HIS A 215
TYR A  72
 None
 0.76A 5y2tA-4uphA:
undetectable		 5y2tA-4uphA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uug AMINE TRANSAMINASE

(Aspergillus
fumigatus) 		PF01063
(Aminotran_4) 		3 SER A  62
HIS A 309
TYR A 305
 FMT  A 403 (-2.5A)
FMT  A 403 (-3.8A)
FMT  A 403 (-4.3A)
 0.85A 5y2tA-4uugA:
undetectable		 5y2tA-4uugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yu5 IMMUNE INHIBITOR A,
METALLOPROTEASE

(Bacillus cereus) 		PF05547
(Peptidase_M6) 		3 SER A 190
HIS A 197
TYR A 208
 None
 0.92A 5y2tA-4yu5A:
undetectable		 5y2tA-4yu5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zrs ESTERASE

(uncultured
bacterium) 		PF07859
(Abhydrolase_3) 		3 SER A 159
HIS A 156
TYR A 198
 None
 0.91A 5y2tA-4zrsA:
undetectable		 5y2tA-4zrsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a55 ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE

(Streptococcus
pneumoniae) 		PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C) 		3 SER A 911
HIS A 477
TYR A 819
 None
 0.90A 5y2tA-5a55A:
undetectable		 5y2tA-5a55A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cwe CYTOCHROME P450
HYDROXYLASE

(Streptomyces
avermitilis) 		PF00067
(p450) 		3 SER A 164
HIS A 235
TYR A 139
 None
 1.03A 5y2tA-5cweA:
undetectable		 5y2tA-5cweA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dfa BETA-GALACTOSIDASE

(Geobacillus
stearothermophilus) 		PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C) 		3 SER A 347
HIS A 343
TYR A 360
 None
 0.92A 5y2tA-5dfaA:
undetectable		 5y2tA-5dfaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ekd TRYPTOPHAN--TRNA
LIGASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00579
(tRNA-synt_1b) 		3 SER A  72
HIS A 120
TYR A 171
 None
 0.97A 5y2tA-5ekdA:
undetectable		 5y2tA-5ekdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9u S-ADENOSYLMETHIONINE
SYNTHASE

(Thermus
thermophilus) 		no annotation 3 SER C 276
HIS C 372
TYR C 289
 None
 1.03A 5y2tA-5h9uC:
undetectable		 5y2tA-5h9uC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1r BURKHOLDERIA
PSEUDOMALLEI
SPHINGOSINE-1-PHOSPH
ATE LYASE BPSS2021

(Burkholderia
pseudomallei) 		PF00282
(Pyridoxal_deC) 		3 SER A  54
HIS A 401
TYR A 208
 None
None
PLP  A 501 ( 4.5A)
 0.77A 5y2tA-5k1rA:
undetectable		 5y2tA-5k1rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k59 UNCHARACTERIZED
LEUKOCIDIN-LIKE
PROTEIN 2

(Staphylococcus
aureus) 		no annotation 3 SER D 181
HIS D 190
TYR D 321
 None
 0.95A 5y2tA-5k59D:
undetectable		 5y2tA-5k59D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2r FUMARATE HYDRATASE

(Leishmania
major) 		PF05681
(Fumerase)
PF05683
(Fumerase_C) 		3 SER A 485
HIS A 425
TYR A 449
 None
 1.03A 5y2tA-5l2rA:
undetectable		 5y2tA-5l2rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc8 ARACHIDONATE
15-LIPOXYGENASE

(Pseudomonas
aeruginosa) 		PF00305
(Lipoxygenase) 		3 SER A 552
HIS A 409
TYR A 623
 None
 0.84A 5y2tA-5lc8A:
undetectable		 5y2tA-5lc8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6u BETA-MANNOSIDASE

(Dictyoglomus
thermophilum) 		PF00703
(Glyco_hydro_2)
PF02837
(Glyco_hydro_2_N) 		3 SER A 448
HIS A 427
TYR A 470
 None
 0.96A 5y2tA-5n6uA:
undetectable		 5y2tA-5n6uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nek PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE

(Bacillus cereus) 		no annotation 3 SER A 127
HIS A 130
TYR A 167
 None
ZN  A 301 ( 3.3A)
None
 1.04A 5y2tA-5nekA:
undetectable		 5y2tA-5nekA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ngw OPGH99A

(Ochrovirga
pacifica) 		no annotation 3 SER A 267
HIS A 238
TYR A 241
 None
 0.96A 5y2tA-5ngwA:
undetectable		 5y2tA-5ngwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5usl IMV MEMBRANE PROTEIN

(Vaccinia virus) 		no annotation 3 SER X 118
HIS X  80
TYR X 169
 None
 0.97A 5y2tA-5uslX:
undetectable		 5y2tA-5uslX:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgz 26S PROTEASOME
REGULATORY SUBUNIT 4
26S PROTEASOME
REGULATORY SUBUNIT 8

(Homo sapiens;
Homo sapiens) 		no annotation
no annotation 		3 SER B 108
HIS B 154
TYR C 121
 None
 0.88A 5y2tA-5vgzB:
undetectable		 5y2tA-5vgzB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlh LBACAS13A H328A
(C2C2)

(Lachnospiraceae
bacterium
NK4A179) 		no annotation 3 SER A1225
HIS A1138
TYR A1152
 None
 0.96A 5y2tA-5wlhA:
undetectable		 5y2tA-5wlhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wp4 PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
1

(Arabidopsis
thaliana) 		no annotation 3 SER A 167
HIS A  19
TYR A  15
 None
 1.03A 5y2tA-5wp4A:
undetectable		 5y2tA-5wp4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwy A TYPE VI-A
CRISPR-CAS
RNA-GUIDED RNA
RIBONUCLEASE, CAS13A

(Leptotrichia
buccalis) 		no annotation 3 SER A 182
HIS A1020
TYR A1016
 None
 0.99A 5y2tA-5xwyA:
undetectable		 5y2tA-5xwyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zq6 SIDE

(Legionella
pneumophila) 		no annotation 3 SER A 854
HIS A 850
TYR A 858
 None
 1.05A 5y2tA-5zq6A:
undetectable		 5y2tA-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bwe PUTATIVE FIMBRIAL
ASSOCIATED
SORTASE-LIKE PROTEIN

(Corynebacterium
diphtheriae) 		no annotation 3 SER A 144
HIS A 140
TYR A  97
 None
 1.04A 5y2tA-6bweA:
undetectable		 5y2tA-6bweA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cbl NEAMINE TRANSAMINASE
NEON

(Streptomyces
fradiae) 		no annotation 3 SER A 217
HIS A 179
TYR A 187
 None
 0.94A 5y2tA-6cblA:
undetectable		 5y2tA-6cblA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cbo C-6'
AMINOTRANSFERASE

(Micromonospora
echinospora) 		no annotation 3 SER A 219
HIS A 181
TYR A 189
 None
 0.89A 5y2tA-6cboA:
undetectable		 5y2tA-6cboA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cdz THYMIDYLATE SYNTHASE

(Escherichia
coli) 		no annotation 3 SER A 167
HIS A 207
TYR A 209
 UMP  A 702 (-2.4A)
UMP  A 702 (-4.0A)
UMP  A 702 ( 4.2A)
 1.05A 5y2tA-6cdzA:
undetectable		 5y2tA-6cdzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cgm RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE

(Bacillus
subtilis) 		no annotation 3 SER A 374
HIS A 368
TYR A 574
 None
 0.99A 5y2tA-6cgmA:
undetectable		 5y2tA-6cgmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cxh PARTICULATE METHANE
MONOOXYGENASE, C
SUBUNIT

(Methylomicrobium
alcaliphilum) 		no annotation 3 SER C 163
HIS C 106
TYR C 174
 None
 0.98A 5y2tA-6cxhC:
undetectable		 5y2tA-6cxhC:
undetectable