SIMILAR PATTERNS OF AMINO ACIDS FOR 5XOO_B_ADNB503_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhg BETA-GLUCURONIDASE

(Homo sapiens) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 LEU A 107
VAL A 105
GLU A  40
LEU A 220
 None
 1.12A 5xooB-1bhgA:
0.0		 5xooB-1bhgA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1djp GLUTAMINASE-ASPARAGI
NASE

(Pseudomonas sp.
7A) 		PF00710
(Asparaginase) 		4 LEU A1078
VAL A1062
GLU A1060
LEU A1015
 None
 1.08A 5xooB-1djpA:
undetectable		 5xooB-1djpA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4o PEROXIREDOXIN 5

(Homo sapiens) 		PF08534
(Redoxin) 		4 LEU A  25
VAL A  23
GLU A  16
LEU A  97
 None
 1.04A 5xooB-1h4oA:
0.0		 5xooB-1h4oA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jf5 ALPHA AMYLASE II

(Thermoactinomyces
vulgaris) 		PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16657
(Malt_amylase_C) 		4 TRP A 553
LEU A 581
VAL A 562
LEU A 571
 None
 1.09A 5xooB-1jf5A:
0.0		 5xooB-1jf5A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jhh LEXA REPRESSOR

(Escherichia
coli) 		PF00717
(Peptidase_S24)
PF01726
(LexA_DNA_bind) 		4 LEU A 113
VAL A 146
GLU A 189
LEU A  88
 None
 1.08A 5xooB-1jhhA:
0.0		 5xooB-1jhhA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1md6 INTERLEUKIN 1
FAMILY, MEMBER 5
(DELTA)

(Mus musculus) 		PF00340
(IL1) 		4 LEU A  79
VAL A  60
GLU A  39
LEU A  20
 None
 1.01A 5xooB-1md6A:
0.0		 5xooB-1md6A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nfg D-HYDANTOINASE

(Ralstonia
pickettii) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		4 LEU A 177
VAL A 372
GLU A 308
LEU A 258
 None
 1.07A 5xooB-1nfgA:
undetectable		 5xooB-1nfgA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1odo PUTATIVE CYTOCHROME
P450 154A1

(Streptomyces
coelicolor) 		PF00067
(p450) 		4 TRP A  81
LEU A  80
VAL A  84
LEU A 237
 PIM  A1408 (-4.6A)
None
None
None
 0.88A 5xooB-1odoA:
0.0		 5xooB-1odoA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qb4 PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Escherichia
coli) 		PF00311
(PEPcase) 		4 LEU A 842
VAL A  71
GLU A  67
LEU A  63
 None
 0.87A 5xooB-1qb4A:
0.0		 5xooB-1qb4A:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tua HYPOTHETICAL PROTEIN
APE0754

(Aeropyrum
pernix) 		PF00013
(KH_1) 		4 LEU A  88
VAL A  90
GLU A 136
LEU A  71
 None
 0.81A 5xooB-1tuaA:
undetectable		 5xooB-1tuaA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v77 HYPOTHETICAL PROTEIN
PH1877

(Pyrococcus
horikoshii) 		PF01876
(RNase_P_p30) 		4 LEU A  78
VAL A  31
GLU A  29
LEU A 207
 None
 1.06A 5xooB-1v77A:
undetectable		 5xooB-1v77A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbo HYPOTHETICAL PROTEIN
BPP1347

(Bordetella
parapertussis) 		PF02190
(LON_substr_bdg) 		4 TRP A 105
LEU A   6
VAL A  45
LEU A  94
 None
 0.88A 5xooB-1zboA:
undetectable		 5xooB-1zboA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a61 TRANSCRIPTIONAL
REGULATOR TM0710

(Thermotoga
maritima) 		PF01047
(MarR) 		4 LEU A  54
VAL A  69
GLU A  73
LEU A  92
 None
 0.98A 5xooB-2a61A:
undetectable		 5xooB-2a61A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2az0 B2 PROTEIN

(Flock House
virus) 		PF11473
(B2) 		4 LEU A  60
VAL A  66
GLU A  70
LEU A   5
 None
 0.98A 5xooB-2az0A:
undetectable		 5xooB-2az0A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c3d 2-OXOPROPYL-COM
REDUCTASE

(Xanthobacter
autotrophicus) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 249
VAL A 227
GLU A 228
LEU A 391
 None
 1.07A 5xooB-2c3dA:
undetectable		 5xooB-2c3dA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c45 ASPARTATE
1-DECARBOXYLASE
PRECURSOR

(Mycobacterium
tuberculosis) 		PF02261
(Asp_decarbox) 		4 LEU A  87
VAL A  44
GLU A  42
LEU A  38
 None
 0.84A 5xooB-2c45A:
undetectable		 5xooB-2c45A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d28 TYPE II SECRETION
ATPASE XPSE

(Xanthomonas
campestris) 		PF05157
(T2SSE_N) 		4 LEU C  25
VAL C  11
GLU C   7
LEU C  39
 None
 1.05A 5xooB-2d28C:
undetectable		 5xooB-2d28C:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dhz RAP GUANINE
NUCLEOTIDE EXCHANGE
FACTOR (GEF)-LIKE 1

(Homo sapiens) 		no annotation 4 LEU A  81
VAL A  77
GLU A  74
LEU A  70
 None
 1.08A 5xooB-2dhzA:
undetectable		 5xooB-2dhzA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ejc PANTOATE--BETA-ALANI
NE LIGASE

(Thermotoga
maritima) 		PF02569
(Pantoate_ligase) 		4 LEU A 273
VAL A 268
GLU A 195
LEU A 191
 None
 1.10A 5xooB-2ejcA:
undetectable		 5xooB-2ejcA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eq9 PYRUVATE
DEHYDROGENASE
COMPLEX,
DIHYDROLIPOAMIDE
DEHYDROGENASE E3
COMPONENT

(Thermus
thermophilus) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 180
VAL A 263
GLU A 261
LEU A 254
 None
 1.03A 5xooB-2eq9A:
undetectable		 5xooB-2eq9A:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f57 SERINE/THREONINE-PRO
TEIN KINASE PAK 7

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 436
VAL A 495
GLU A 494
LEU A 491
 None
 1.01A 5xooB-2f57A:
3.4		 5xooB-2f57A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g4s NEXT TO BRCA1 GENE 1
PROTEIN

(Homo sapiens) 		PF00564
(PB1) 		4 LEU A   7
VAL A   5
GLU A   2
LEU A  68
 None
None
None
ACY  A  87 (-4.5A)
 1.11A 5xooB-2g4sA:
undetectable		 5xooB-2g4sA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h1i CARBOXYLESTERASE

(Bacillus cereus) 		PF02230
(Abhydrolase_2) 		4 LEU A  33
VAL A 191
GLU A 190
LEU A 186
 None
 1.05A 5xooB-2h1iA:
undetectable		 5xooB-2h1iA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hoq PUTATIVE
HAD-HYDROLASE PH1655

(Pyrococcus
horikoshii) 		PF13419
(HAD_2) 		4 LEU A 106
VAL A 102
GLU A 218
LEU A 221
 None
 1.08A 5xooB-2hoqA:
undetectable		 5xooB-2hoqA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hu9 MERCURIC TRANSPORT
PROTEIN PERIPLASMIC
COMPONENT

(Archaeoglobus
fulgidus) 		no annotation 4 TRP A 121
VAL A  74
GLU A  82
LEU A 126
 ACY  A 301 (-4.9A)
ACY  A 301 ( 4.9A)
None
None
 1.00A 5xooB-2hu9A:
undetectable		 5xooB-2hu9A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jnw DNA EXCISION REPAIR
PROTEIN ERCC-1

(Homo sapiens) 		PF03834
(Rad10) 		4 TRP A 200
LEU A 198
VAL A 171
LEU A 182
 None
 1.07A 5xooB-2jnwA:
undetectable		 5xooB-2jnwA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p0y HYPOTHETICAL PROTEIN
LP_0780

(Lactobacillus
plantarum) 		PF01933
(UPF0052) 		4 LEU A 261
VAL A 224
GLU A 222
LEU A 325
 None
 0.81A 5xooB-2p0yA:
undetectable		 5xooB-2p0yA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pwj MITOCHONDRIAL
PEROXIREDOXIN

(Pisum sativum) 		PF08534
(Redoxin) 		4 LEU A 150
VAL A 152
GLU A 136
LEU A 122
 None
 1.07A 5xooB-2pwjA:
undetectable		 5xooB-2pwjA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qr4 PEPTIDASE M3B,
OLIGOENDOPEPTIDASE F

(Enterococcus
faecium) 		PF01432
(Peptidase_M3)
PF08439
(Peptidase_M3_N) 		4 LEU A 198
VAL A 196
GLU A 191
LEU A 206
 None
 1.12A 5xooB-2qr4A:
undetectable		 5xooB-2qr4A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzi EXTRACELLULAR
SIALIDASE/NEURAMINID
ASE, PUTATIVE

(Aspergillus
fumigatus) 		PF13088
(BNR_2) 		4 LEU A 314
VAL A 373
GLU A 355
LEU A 344
 None
 1.02A 5xooB-2xziA:
undetectable		 5xooB-2xziA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0r SENSOR PROTEIN

(Thermotoga
maritima) 		PF00512
(HisKA)
PF00989
(PAS)
PF02518
(HATPase_c) 		4 LEU A 655
VAL A 618
GLU A 617
LEU A 614
 None
 0.88A 5xooB-3a0rA:
undetectable		 5xooB-3a0rA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Mus musculus) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 TRP B 426
LEU B 448
VAL B 444
LEU B 435
 None
 1.05A 5xooB-3a79B:
undetectable		 5xooB-3a79B:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE

(Staphylococcus
epidermidis) 		PF01715
(IPPT) 		4 LEU A 252
VAL A 230
GLU A 229
LEU A 226
 None
 0.98A 5xooB-3d3qA:
undetectable		 5xooB-3d3qA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ew7 LMO0794 PROTEIN

(Listeria
monocytogenes) 		PF13460
(NAD_binding_10) 		4 TRP A 150
LEU A  98
VAL A 100
LEU A  83
 None
 0.89A 5xooB-3ew7A:
undetectable		 5xooB-3ew7A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE

(Glutamicibacter
protophormiae) 		PF03644
(Glyco_hydro_85) 		4 LEU A 597
VAL A 595
GLU A 588
LEU A 586
 None
 1.09A 5xooB-3fhaA:
undetectable		 5xooB-3fhaA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g3s GCN5-RELATED
N-ACETYLTRANSFERASE

(Streptococcus
suis) 		PF12746
(GNAT_acetyltran) 		4 LEU A  64
VAL A  88
GLU A  87
LEU A  84
 None
 1.05A 5xooB-3g3sA:
undetectable		 5xooB-3g3sA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5t TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Corynebacterium
glutamicum) 		PF00356
(LacI)
PF13377
(Peripla_BP_3) 		4 LEU A 213
VAL A 208
GLU A 246
LEU A 199
 None
 1.06A 5xooB-3h5tA:
undetectable		 5xooB-3h5tA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hsi PHOSPHATIDYLSERINE
SYNTHASE

(Haemophilus
influenzae) 		PF13091
(PLDc_2) 		4 LEU A 373
VAL A 259
GLU A 255
LEU A 246
 None
 1.07A 5xooB-3hsiA:
undetectable		 5xooB-3hsiA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iom PURINE NUCLEOSIDE
PHOSPHORYLASE

(Mycobacterium
tuberculosis) 		PF01048
(PNP_UDP_1) 		4 TRP A  38
LEU A  34
VAL A  32
LEU A  45
 None
 0.74A 5xooB-3iomA:
undetectable		 5xooB-3iomA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jrq PUTATIVE
UNCHARACTERIZED
PROTEIN AT5G46790

(Arabidopsis
thaliana) 		PF10604
(Polyketide_cyc2) 		4 LEU B 170
VAL B 168
GLU B  36
LEU B  32
 None
 1.13A 5xooB-3jrqB:
undetectable		 5xooB-3jrqB:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldr FRUCTOSYLTRANSFERASE

(Aspergillus
japonicus) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 LEU A 475
VAL A 595
GLU A 602
LEU A 423
 None
 0.97A 5xooB-3ldrA:
undetectable		 5xooB-3ldrA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n54 SPORE GERMINATION
PROTEIN B3

(Bacillus
subtilis) 		PF05504
(Spore_GerAC) 		4 LEU B 319
VAL B 315
GLU B 224
LEU B 220
 None
 0.96A 5xooB-3n54B:
undetectable		 5xooB-3n54B:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oji ABSCISIC ACID
RECEPTOR PYL3

(Arabidopsis
thaliana) 		PF10604
(Polyketide_cyc2) 		4 LEU A 169
VAL A 167
GLU A  29
LEU A  25
 None
 0.89A 5xooB-3ojiA:
undetectable		 5xooB-3ojiA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p2t LEUKOCYTE
IMMUNOGLOBULIN-LIKE
RECEPTOR SUBFAMILY B
MEMBER 4

(Homo sapiens) 		PF00047
(ig)
PF13895
(Ig_2) 		4 LEU A 183
VAL A  93
GLU A  91
LEU A 141
 None
 1.12A 5xooB-3p2tA:
undetectable		 5xooB-3p2tA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN

(Listeria
monocytogenes) 		PF02126
(PTE) 		4 LEU A 256
VAL A 259
GLU A 264
LEU A 313
 None
 1.00A 5xooB-3pnzA:
undetectable		 5xooB-3pnzA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qwx CELL DEATH
ABNORMALITY PROTEIN
2

(Caenorhabditis
elegans) 		PF00017
(SH2)
PF00018
(SH3_1) 		4 LEU X  51
VAL X  53
GLU X  55
LEU X 104
 None
 1.01A 5xooB-3qwxX:
undetectable		 5xooB-3qwxX:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qwy CELL DEATH
ABNORMALITY PROTEIN
2

(Caenorhabditis
elegans) 		PF00017
(SH2)
PF00018
(SH3_1) 		4 LEU A  51
VAL A  53
GLU A  55
LEU A 104
 None
 1.00A 5xooB-3qwyA:
undetectable		 5xooB-3qwyA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Mycobacteroides
abscessus) 		PF01259
(SAICAR_synt) 		4 LEU A  28
VAL A  83
GLU A  82
LEU A   5
 LEU  A  28 ( 0.6A)
VAL  A  83 ( 0.6A)
GLU  A  82 ( 0.5A)
LEU  A   5 ( 0.6A)
 0.93A 5xooB-3r9rA:
3.0		 5xooB-3r9rA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3su8 PLEXIN-B1

(Homo sapiens) 		PF08337
(Plexin_cytopl) 		4 LEU X1660
VAL X1683
GLU X1684
LEU X1676
 None
 1.03A 5xooB-3su8X:
undetectable		 5xooB-3su8X:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ueb PUTATIVE
UNCHARACTERIZED
PROTEIN

(Thermococcus
onnurineus) 		PF11419
(DUF3194) 		4 LEU A  70
VAL A  72
GLU A  46
LEU A  42
 None
 0.86A 5xooB-3uebA:
undetectable		 5xooB-3uebA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ugg SUCROSE:(SUCROSE/FRU
CTAN)
6-FRUCTOSYLTRANSFERA
SE

(Pachysandra
terminalis) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 LEU A 516
VAL A 370
GLU A 535
LEU A 376
 None
 0.83A 5xooB-3uggA:
undetectable		 5xooB-3uggA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uy4 PANTOTHENATE
SYNTHETASE

(Campylobacter
jejuni) 		PF02569
(Pantoate_ligase) 		4 LEU A 272
VAL A 267
GLU A 194
LEU A 190
 None
 1.03A 5xooB-3uy4A:
undetectable		 5xooB-3uy4A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zvu ABSCISIC ACID
RECEPTOR PYR1

(Arabidopsis
thaliana) 		PF10604
(Polyketide_cyc2) 		4 LEU A 140
VAL A 138
GLU A   9
LEU A   5
 None
 1.02A 5xooB-3zvuA:
undetectable		 5xooB-3zvuA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a8e PROBABLE TYROSINE
RECOMBINASE
XERC-LIKE

(Pyrococcus
abyssi) 		PF00589
(Phage_integrase)
PF02899
(Phage_int_SAM_1) 		4 LEU A 223
VAL A 221
GLU A 109
LEU A 105
 None
 0.91A 5xooB-4a8eA:
undetectable		 5xooB-4a8eA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c0d CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3

(Homo sapiens) 		PF04054
(Not1)
PF04153
(NOT2_3_5) 		4 LEU A2039
VAL A2035
GLU C 618
LEU A2091
 None
 1.03A 5xooB-4c0dA:
undetectable		 5xooB-4c0dA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d1e ALPHA-ACTININ-2

(Homo sapiens) 		PF00307
(CH)
PF00435
(Spectrin)
PF08726
(EFhand_Ca_insen) 		4 LEU A  52
VAL A  78
GLU A  77
LEU A  74
 None
None
None
MLZ  A  71 ( 4.2A)
 0.98A 5xooB-4d1eA:
undetectable		 5xooB-4d1eA:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dxb MALTOSE-BINDING
PERIPLASMIC PROTEIN,
BETA-LACTAMASE TEM
CHIMERA

(Escherichia
coli) 		PF01547
(SBP_bac_1)
PF13354
(Beta-lactamase2) 		4 LEU A 576
VAL A 347
GLU A 404
LEU A 372
 None
 1.06A 5xooB-4dxbA:
undetectable		 5xooB-4dxbA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f3n UNCHARACTERIZED ACR,
COG1565 SUPERFAMILY

(Burkholderia
thailandensis) 		PF02636
(Methyltransf_28) 		4 LEU A 103
VAL A 190
GLU A 121
LEU A 129
 None
 1.10A 5xooB-4f3nA:
undetectable		 5xooB-4f3nA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f52 GLOMULIN

(Homo sapiens) 		PF08568
(Kinetochor_Ybp2) 		4 LEU E 478
VAL E 575
GLU E 576
LEU E 506
 None
 1.03A 5xooB-4f52E:
undetectable		 5xooB-4f52E:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2t SSFS6

(Streptomyces
sp. SF2575) 		PF00201
(UDPGT)
PF06722
(DUF1205) 		4 LEU A  92
VAL A  62
GLU A  61
LEU A  57
 None
 0.91A 5xooB-4g2tA:
undetectable		 5xooB-4g2tA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ina SACCHAROPINE
DEHYDROGENASE

(Wolinella
succinogenes) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		4 LEU A   5
VAL A  75
GLU A  74
LEU A  71
 None
 1.00A 5xooB-4inaA:
undetectable		 5xooB-4inaA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jgh CULLIN-5

(Homo sapiens) 		PF00888
(Cullin) 		4 LEU D  65
VAL D 135
GLU D 115
LEU D 114
 None
 1.04A 5xooB-4jghD:
undetectable		 5xooB-4jghD:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgn CELLULOSE-BINDING,
FAMILY II

(Acidothermus
cellulolyticus) 		no annotation 4 TRP A  45
LEU A  33
VAL A  35
LEU A 397
 None
 1.06A 5xooB-4lgnA:
undetectable		 5xooB-4lgnA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nnq PUTATIVE ENOYL-COA
HYDRATASE

(Streptomyces
atroolivaceus) 		PF00378
(ECH_1) 		4 LEU A 155
VAL A 151
GLU A 141
LEU A 139
 None
 1.07A 5xooB-4nnqA:
undetectable		 5xooB-4nnqA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4npa PUTATIVE
UNCHARACTERIZED
PROTEIN

(Vibrio cholerae) 		PF03641
(Lysine_decarbox)
PF11892
(DUF3412)
PF14793
(DUF4478) 		4 LEU A 106
VAL A 110
GLU A  23
LEU A  19
 None
 0.60A 5xooB-4npaA:
undetectable		 5xooB-4npaA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfb C4-DICARBOXYLATE-BIN
DING PROTEIN

(Fusobacterium
nucleatum) 		PF03480
(DctP) 		4 LEU A 198
VAL A 222
GLU A 151
LEU A 206
 None
 0.90A 5xooB-4pfbA:
undetectable		 5xooB-4pfbA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7t DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A

(Homo sapiens) 		PF00145
(DNA_methylase) 		4 TRP A 860
LEU A 859
VAL A 850
LEU A 819
 None
 1.02A 5xooB-4u7tA:
undetectable		 5xooB-4u7tA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmm NUCLEOPORIN SEH1

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 TRP C 173
LEU C 171
VAL C 185
LEU C 134
 None
 0.97A 5xooB-4xmmC:
undetectable		 5xooB-4xmmC:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y4q SORTASE, SRTB FAMILY

(Streptococcus
pneumoniae) 		PF04203
(Sortase) 		4 LEU A 237
VAL A 253
GLU A 188
LEU A 217
 None
 1.09A 5xooB-4y4qA:
undetectable		 5xooB-4y4qA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bp3 MYCOCEROSIC ACID
SYNTHASE-LIKE
POLYKETIDE SYNTHASE

(Mycolicibacterium
smegmatis) 		PF14765
(PS-DH) 		4 LEU A1167
VAL A1094
GLU A 949
LEU A 952
 None
 1.12A 5xooB-5bp3A:
undetectable		 5xooB-5bp3A:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bwi GLYCOSIDE HYDROLASE
FAMILY 79

(Burkholderia
pseudomallei) 		PF12891
(Glyco_hydro_44) 		4 LEU A 281
VAL A 277
GLU A 320
LEU A 294
 None
 1.03A 5xooB-5bwiA:
undetectable		 5xooB-5bwiA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dbk TRANSCRIPTIONAL
REGULATOR/TPR DOMAIN
PROTEIN

(Bacillus
thuringiensis) 		PF13424
(TPR_12) 		4 LEU A  76
VAL A  72
GLU A 101
LEU A  98
 None
 1.03A 5xooB-5dbkA:
undetectable		 5xooB-5dbkA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fji BETA-GLUCOSIDASE

(Aspergillus
fumigatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 LEU A 501
VAL A 419
GLU A 416
LEU A 412
 None
 1.12A 5xooB-5fjiA:
undetectable		 5xooB-5fjiA:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fji BETA-GLUCOSIDASE

(Aspergillus
fumigatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 LEU A 501
VAL A 499
GLU A 416
LEU A 412
 None
 1.11A 5xooB-5fjiA:
undetectable		 5xooB-5fjiA:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fxv HISTONE DEMETHYLASE
UTY

(Homo sapiens) 		PF02373
(JmjC) 		4 LEU A1257
VAL A1264
GLU A1323
LEU A1288
 None
 1.00A 5xooB-5fxvA:
undetectable		 5xooB-5fxvA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h04 BINARY ENTEROTOXIN
OF CLOSTRIDIUM
PERFRINGENS
COMPONENT A

(Clostridium
perfringens) 		PF03496
(ADPrib_exo_Tox) 		4 LEU A 384
VAL A 371
GLU A 375
LEU A 248
 None
None
None
NAI  A 501 (-4.7A)
 1.07A 5xooB-5h04A:
undetectable		 5xooB-5h04A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h11 UNCHARACTERIZED
PROTEIN

(Danio rerio) 		PF07393
(Sec10) 		4 LEU A 219
VAL A 215
GLU A 199
LEU A 196
 None
 1.00A 5xooB-5h11A:
undetectable		 5xooB-5h11A:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hyz GRAS FAMILY
TRANSCRIPTION FACTOR
CONTAINING PROTEIN,
EXPRESSED

(Oryza sativa) 		PF03514
(GRAS) 		4 LEU A 286
VAL A 486
GLU A 487
LEU A 472
 None
 1.01A 5xooB-5hyzA:
undetectable		 5xooB-5hyzA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jcp ARF-GAP WITH RHO-GAP
DOMAIN, ANK REPEAT
AND PH
DOMAIN-CONTAINING
PROTEIN
3,LINKER,TRANSFORMIN
G PROTEIN RHOA

(Homo sapiens;
synthetic
construct) 		no annotation 4 LEU B 966
VAL B 964
GLU B 956
LEU B 953
 None
 0.85A 5xooB-5jcpB:
undetectable		 5xooB-5jcpB:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jn0 CRK-II SH2 DOMAIN

(Homo sapiens) 		PF00017
(SH2) 		4 LEU A  49
VAL A  51
GLU A  53
LEU A  92
 None
 0.87A 5xooB-5jn0A:
undetectable		 5xooB-5jn0A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqk PEPTIDASE, PUTATIVE

(Plasmodium
falciparum) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2) 		4 LEU A 328
VAL A 468
GLU A 349
LEU A 344
 None
 1.07A 5xooB-5jqkA:
undetectable		 5xooB-5jqkA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ju6 BETA-GLUCOSIDASE

(Rasamsonia
emersonii) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 LEU A 496
VAL A 414
GLU A 411
LEU A 407
 None
 1.09A 5xooB-5ju6A:
undetectable		 5xooB-5ju6A:
5.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jvk UNCHARACTERIZED
PROTEIN

(Bacteroides
cellulosilyticus) 		no annotation 4 TRP A 165
LEU A 230
VAL A 266
LEU A 246
 None
 1.00A 5xooB-5jvkA:
undetectable		 5xooB-5jvkA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B

(Escherichia
coli) 		PF01569
(PAP2) 		4 LEU A 137
VAL A 133
GLU A 111
LEU A 110
 None
 1.07A 5xooB-5jwyA:
undetectable		 5xooB-5jwyA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5keu TAURINE DIOXYGENASE

(Paraburkholderia
xenovorans) 		PF02668
(TauD) 		4 LEU A  30
VAL A  28
GLU A  38
LEU A  34
 None
 0.98A 5xooB-5keuA:
undetectable		 5xooB-5keuA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n8o DNA HELICASE I

(Escherichia
coli) 		PF07057
(TraI)
PF08751
(TrwC)
PF13604
(AAA_30) 		4 LEU A1155
VAL A1445
GLU A1417
LEU A1436
 None
 1.05A 5xooB-5n8oA:
undetectable		 5xooB-5n8oA:
3.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III

(Bacteroides
thetaiotaomicron) 		no annotation 4 LEU A 520
VAL A 615
GLU A 614
LEU A 611
 None
 1.10A 5xooB-5na7A:
undetectable		 5xooB-5na7A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o34 ENOYL-COA HYDRATASE
CARB HOMOLOGUE

(Streptomyces
cattleya) 		no annotation 4 LEU A 229
VAL A 224
GLU A 222
LEU A 165
 None
 0.85A 5xooB-5o34A:
undetectable		 5xooB-5o34A:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7

(Homo sapiens) 		PF00293
(NUDIX) 		4 LEU A  24
VAL A 108
GLU A 106
LEU A 128
 None
EDO  A 302 (-4.6A)
None
None
 0.95A 5xooB-5t3pA:
undetectable		 5xooB-5t3pA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubk ACYL-HOMOSERINE
LACTONE ACYLASE PVDQ

(Pseudomonas
aeruginosa) 		PF01804
(Penicil_amidase) 		4 TRP A 134
LEU A 138
VAL A 132
LEU A  78
 None
 1.12A 5xooB-5ubkA:
undetectable		 5xooB-5ubkA:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve3 BPPRF

(Paraburkholderia
phytofirmans) 		no annotation 4 LEU B 297
VAL B 271
GLU B 269
LEU B 304
 None
 0.75A 5xooB-5ve3B:
undetectable		 5xooB-5ve3B:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8u ORF1AB PROTEIN

(Middle East
respiratory
syndrome-related
coronavirus) 		PF08715
(Viral_protease) 		4 LEU A  80
VAL A  10
GLU A  64
LEU A  60
 None
 1.12A 5xooB-5w8uA:
undetectable		 5xooB-5w8uA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xh9 EXTRACELLULAR
INVERTASE

(Aspergillus
kawachii) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 LEU A 449
VAL A 568
GLU A 575
LEU A 395
 None
 1.00A 5xooB-5xh9A:
undetectable		 5xooB-5xh9A:
10.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5xom GLYCOSAMINOGLYCAN
XYLOSYLKINASE

(Hydra vulgaris) 		no annotation 4 LEU A 236
VAL A 242
GLU A 304
LEU A 317
 None
 0.34A 5xooB-5xomA:
57.9		 5xooB-5xomA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xs2 CYCLIN-C

(Homo sapiens) 		PF00134
(Cyclin_N)
PF16899
(Cyclin_C_2) 		4 LEU B 159
VAL B 163
GLU B 169
LEU B 173
 None
 1.07A 5xooB-5xs2B:
undetectable		 5xooB-5xs2B:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus) 		no annotation 4 LEU A 756
VAL A 778
GLU A 777
LEU A 774
 None
 1.12A 5xooB-5zlnA:
undetectable		 5xooB-5zlnA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cxd PEPTIDASE B

(Yersinia pestis) 		no annotation 4 LEU A 193
VAL A 242
GLU A 240
LEU A 426
 None
 0.85A 5xooB-6cxdA:
undetectable		 5xooB-6cxdA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6evg MULTI-COPPER OXIDASE
CUEO

(Ochrobactrum) 		no annotation 4 LEU A  78
VAL A  76
GLU A  74
LEU A  70
 None
 0.82A 5xooB-6evgA:
undetectable		 5xooB-6evgA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT 6
MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6

(Polytomella sp.
Pringsheim
198.80) 		no annotation 4 LEU N 108
VAL M 285
GLU M 288
LEU M 251
 None
 1.10A 5xooB-6f36N:
undetectable		 5xooB-6f36N:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gt1 SERINE/THREONINE-PRO
TEIN KINASE NEK7

(Homo sapiens) 		no annotation 4 LEU A 226
VAL A 138
GLU A 135
LEU A 267
 None
 1.08A 5xooB-6gt1A:
undetectable		 5xooB-6gt1A:
undetectable