SIMILAR PATTERNS OF AMINO ACIDS FOR 5X80_A_SALA201_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1al8 | GLYCOLATE OXIDASE (Spinaciaoleracea) |
PF01070(FMN_dh) | 4 | VAL A 288ARG A 289PRO A 310GLY A 308 | NoneFMN A 360 (-2.9A)NoneFMN A 360 (-3.5A) | 0.94A | 5x80A-1al8A:0.05x80B-1al8A:0.0 | 5x80A-1al8A:22.285x80B-1al8A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fn4 | MONOCLONAL ANTIBODYAGAINSTACETYLCHOLINERECEPTOR (Rattusnorvegicus) |
PF07654(C1-set)PF07686(V-set) | 4 | VAL B 34PRO B 100GLY B 100TYR B 100 | None | 1.03A | 5x80A-1fn4B:undetectable5x80B-1fn4B:undetectable | 5x80A-1fn4B:19.825x80B-1fn4B:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i2m | REGULATOR OFCHROMOSOMECONDENSATION 1 (Homo sapiens) |
PF00415(RCC1) | 4 | VAL B 80PRO B 112GLY B 113TYR B 89 | None | 1.30A | 5x80A-1i2mB:undetectable5x80B-1i2mB:undetectable | 5x80A-1i2mB:19.105x80B-1i2mB:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jm7 | BRCA1-ASSOCIATEDRING DOMAIN PROTEIN1 (Homo sapiens) |
PF14835(zf-RING_6) | 4 | VAL B 75ARG B 52PRO B 84GLY B 82 | None | 1.14A | 5x80A-1jm7B:undetectable5x80B-1jm7B:undetectable | 5x80A-1jm7B:21.125x80B-1jm7B:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k26 | NUDIX HOMOLOG (Pyrobaculumaerophilum) |
PF00293(NUDIX) | 4 | VAL A 14PRO A 28GLY A 6TYR A 27 | None | 1.22A | 5x80A-1k26A:undetectable5x80B-1k26A:undetectable | 5x80A-1k26A:22.735x80B-1k26A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ltd | FLAVOCYTOCHROME B2 (Saccharomycescerevisiae) |
PF00173(Cyt-b5)PF01070(FMN_dh) | 4 | VAL A 412ARG A 413PRO A 434GLY A 432 | NoneFMN A 570 (-3.9A)NoneFMN A 570 (-3.8A) | 0.94A | 5x80A-1ltdA:0.45x80B-1ltdA:0.0 | 5x80A-1ltdA:16.855x80B-1ltdA:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ms8 | TRANS-SIALIDASE (Trypanosomacruzi) |
PF13385(Laminin_G_3)PF13859(BNR_3) | 4 | VAL A 181PRO A 193GLY A 178TYR A 192 | None | 1.34A | 5x80A-1ms8A:undetectable5x80B-1ms8A:undetectable | 5x80A-1ms8A:14.045x80B-1ms8A:14.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1od5 | GLYCININ (Glycine max) |
PF00190(Cupin_1) | 4 | VAL A 204PRO A 169GLY A 167TYR A 164 | None | 1.19A | 5x80A-1od5A:0.05x80B-1od5A:0.0 | 5x80A-1od5A:13.625x80B-1od5A:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1puo | MAJOR ALLERGEN IPOLYPEPTIDE, FUSEDCHAIN 2, CHAIN 1 (Felis catus) |
PF01099(Uteroglobin)PF09252(Feld-I_B) | 4 | VAL A 137PRO A 110GLY A 108TYR A 113 | None | 1.18A | 5x80A-1puoA:2.35x80B-1puoA:1.7 | 5x80A-1puoA:26.145x80B-1puoA:26.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qcw | FLAVOCYTOCHROME B2 (Saccharomycescerevisiae) |
PF01070(FMN_dh) | 4 | VAL A 412ARG A 413PRO A 434GLY A 432 | NoneFNS A 570 (-3.3A)NoneFNS A 570 (-3.4A) | 0.95A | 5x80A-1qcwA:0.05x80B-1qcwA:0.2 | 5x80A-1qcwA:17.755x80B-1qcwA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sp0 | CYTOCHROME C OXIDASEASSEMBLY PROTEINCTAG (Sinorhizobiummeliloti) |
PF04442(CtaG_Cox11) | 4 | VAL A 41PRO A 146GLY A 44TYR A 145 | None | 1.35A | 5x80A-1sp0A:undetectable5x80B-1sp0A:undetectable | 5x80A-1sp0A:21.915x80B-1sp0A:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sy7 | CATALASE 1 (Neurosporacrassa) |
PF00199(Catalase)PF01965(DJ-1_PfpI)PF06628(Catalase-rel) | 4 | VAL A 569PRO A 623GLY A 624TYR A 566 | None | 1.32A | 5x80A-1sy7A:0.05x80B-1sy7A:0.0 | 5x80A-1sy7A:11.805x80B-1sy7A:11.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t07 | HYPOTHETICAL UPF0269PROTEIN PA5148 (Pseudomonasaeruginosa) |
PF04362(Iron_traffic) | 4 | VAL A 34PRO A 21GLY A 27TYR A 31 | None | 1.33A | 5x80A-1t07A:0.45x80B-1t07A:0.5 | 5x80A-1t07A:19.885x80B-1t07A:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t1j | HYPOTHETICAL PROTEIN (Pseudomonasaeruginosa) |
PF09152(DUF1937) | 4 | VAL A 17ARG A 21PRO A 9GLY A 86 | None | 1.45A | 5x80A-1t1jA:0.05x80B-1t1jA:0.0 | 5x80A-1t1jA:25.005x80B-1t1jA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v5v | AMINOMETHYLTRANSFERASE (Pyrococcushorikoshii) |
PF01571(GCV_T)PF08669(GCV_T_C) | 4 | VAL A 52ARG A 251GLY A 197TYR A 198 | None | 1.11A | 5x80A-1v5vA:0.05x80B-1v5vA:0.0 | 5x80A-1v5vA:16.715x80B-1v5vA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wop | AMINOMETHYLTRANSFERASE (Thermotogamaritima) |
PF01571(GCV_T)PF08669(GCV_T_C) | 4 | VAL A 48ARG A 227GLY A 187TYR A 188 | NoneFFO A2887 (-3.6A)NoneFFO A2887 (-3.5A) | 1.13A | 5x80A-1wopA:undetectable5x80B-1wopA:undetectable | 5x80A-1wopA:17.965x80B-1wopA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wsv | AMINOMETHYLTRANSFERASE (Homo sapiens) |
PF01571(GCV_T)PF08669(GCV_T_C) | 4 | VAL A 53ARG A 233GLY A 196TYR A 197 | VAL A 53 ( 0.6A)ARG A 233 (-0.6A)GLY A 196 (-0.0A)TYR A 197 (-1.3A) | 1.03A | 5x80A-1wsvA:undetectable5x80B-1wsvA:undetectable | 5x80A-1wsvA:20.125x80B-1wsvA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zq1 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT D (Pyrococcusabyssi) |
PF00710(Asparaginase) | 4 | VAL A 223PRO A 198GLY A 171TYR A 170 | None | 1.36A | 5x80A-1zq1A:undetectable5x80B-1zq1A:undetectable | 5x80A-1zq1A:16.675x80B-1zq1A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aey | FRUCTAN1-EXOHYDROLASE IIA (Cichoriumintybus) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 4 | VAL A 461PRO A 389GLY A 458TYR A 270 | None | 1.35A | 5x80A-2aeyA:undetectable5x80B-2aeyA:undetectable | 5x80A-2aeyA:15.645x80B-2aeyA:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b3x | IRON-RESPONSIVEELEMENT BINDINGPROTEIN 1 (Homo sapiens) |
PF00330(Aconitase)PF00694(Aconitase_C) | 4 | VAL A 477PRO A 473GLY A 474TYR A 501 | None | 1.32A | 5x80A-2b3xA:undetectable5x80B-2b3xA:undetectable | 5x80A-2b3xA:11.435x80B-2b3xA:11.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0o | DIOLDEHYDRATASE-REACTIVATING FACTOR LARGESUBUNIT (Klebsiellaoxytoca) |
PF08841(DDR) | 4 | VAL A 203ARG A 242PRO A 106GLY A 107 | None | 1.17A | 5x80A-2d0oA:2.25x80B-2d0oA:undetectable | 5x80A-2d0oA:15.085x80B-2d0oA:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3t | FATTY OXIDATIONCOMPLEX ALPHASUBUNIT (Pseudomonasfragi) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 4 | VAL A 153PRO A 147GLY A 148TYR A 146 | None | 1.08A | 5x80A-2d3tA:undetectable5x80B-2d3tA:1.3 | 5x80A-2d3tA:14.875x80B-2d3tA:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d5a | HYPOTHETICAL PROTEINPH1109 (Pyrococcushorikoshii) |
PF13380(CoA_binding_2) | 4 | VAL A 128ARG A 131PRO A 6GLY A 9 | None | 1.37A | 5x80A-2d5aA:undetectable5x80B-2d5aA:undetectable | 5x80A-2d5aA:21.845x80B-2d5aA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i6e | HYPOTHETICAL PROTEIN (Deinococcusradiodurans) |
PF02621(VitK2_biosynth) | 4 | VAL A 132ARG A 106GLY A 150TYR A 148 | None | 1.43A | 5x80A-2i6eA:undetectable5x80B-2i6eA:undetectable | 5x80A-2i6eA:23.335x80B-2i6eA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nli | LACTATE OXIDASE (Aerococcusviridans) |
PF01070(FMN_dh) | 4 | VAL A 299ARG A 300PRO A 321GLY A 319 | NoneFMN A1375 (-2.9A)NoneFMN A1375 (-3.3A) | 1.03A | 5x80A-2nliA:undetectable5x80B-2nliA:undetectable | 5x80A-2nliA:19.555x80B-2nliA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q83 | YTAA PROTEIN (Bacillussubtilis) |
PF01636(APH) | 4 | VAL A 69PRO A 99GLY A 100TYR A 121 | NoneADN A 1 ( 4.9A)NoneNone | 1.12A | 5x80A-2q83A:undetectable5x80B-2q83A:undetectable | 5x80A-2q83A:20.905x80B-2q83A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qqu | BETA-FRUCTOFURANOSIDASE (Arabidopsisthaliana) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 4 | VAL A 469PRO A 395GLY A 466TYR A 275 | None | 1.30A | 5x80A-2qquA:undetectable5x80B-2qquA:undetectable | 5x80A-2qquA:14.095x80B-2qquA:14.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2spt | PROTHROMBIN (Bos taurus) |
PF00051(Kringle)PF00594(Gla) | 4 | VAL A 143PRO A 125GLY A 71TYR A 74 | None | 1.36A | 5x80A-2sptA:undetectable5x80B-2sptA:undetectable | 5x80A-2sptA:22.445x80B-2sptA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vgi | PYRUVATE KINASEISOZYMES R/L (Homo sapiens) |
PF00224(PK)PF02887(PK_C) | 4 | ARG A 518PRO A 145GLY A 143TYR A 148 | None | 0.91A | 5x80A-2vgiA:undetectable5x80B-2vgiA:undetectable | 5x80A-2vgiA:16.635x80B-2vgiA:16.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wrt | GLUTATHIONES-TRANSFERASECLASS-MU 26 KDAISOZYME 51 (Fasciolahepatica) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | VAL A 17ARG A 18GLY A 6TYR A 7 | None | 1.42A | 5x80A-2wrtA:undetectable5x80B-2wrtA:undetectable | 5x80A-2wrtA:21.175x80B-2wrtA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ybu | ACIDIC MAMMALIANCHITINASE (Homo sapiens) |
PF00704(Glyco_hydro_18) | 4 | VAL A 184PRO A 142GLY A 194TYR A 141 | None | 1.28A | 5x80A-2ybuA:undetectable5x80B-2ybuA:undetectable | 5x80A-2ybuA:16.805x80B-2ybuA:16.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zxq | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Bifidobacteriumlongum) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 4 | VAL A 993ARG A 977PRO A 871GLY A 996 | None | 1.44A | 5x80A-2zxqA:undetectable5x80B-2zxqA:undetectable | 5x80A-2zxqA:9.575x80B-2zxqA:9.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a8k | AMINOMETHYLTRANSFERASE (Escherichiacoli) |
PF01571(GCV_T)PF08669(GCV_T_C) | 4 | VAL A 48ARG A 223GLY A 187TYR A 188 | None | 0.96A | 5x80A-3a8kA:undetectable5x80B-3a8kA:undetectable | 5x80A-3a8kA:19.895x80B-3a8kA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3al0 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT A (Thermotogamaritima) |
PF01425(Amidase) | 4 | VAL A 207PRO A 202GLY A 177TYR A 178 | None | 0.94A | 5x80A-3al0A:undetectable5x80B-3al0A:undetectable | 5x80A-3al0A:16.455x80B-3al0A:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3apm | PROTEIN-ARGININEDEIMINASE TYPE-4 (Homo sapiens) |
PF03068(PAD)PF08526(PAD_N)PF08527(PAD_M) | 4 | VAL A 456PRO A 424GLY A 426TYR A 423 | None | 1.23A | 5x80A-3apmA:undetectable5x80B-3apmA:undetectable | 5x80A-3apmA:14.025x80B-3apmA:14.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmb | ACETOACETATEDECARBOXYLASE (Methanoculleusmarisnigri) |
PF06314(ADC) | 4 | VAL A 197PRO A 200GLY A 259TYR A 199 | NoneNoneNoneP33 A 269 (-3.8A) | 1.34A | 5x80A-3cmbA:undetectable5x80B-3cmbA:undetectable | 5x80A-3cmbA:23.055x80B-3cmbA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dzc | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Vibrio cholerae) |
PF02350(Epimerase_2) | 4 | VAL A 174PRO A 149GLY A 171TYR A 357 | None | 1.43A | 5x80A-3dzcA:undetectable5x80B-3dzcA:undetectable | 5x80A-3dzcA:20.605x80B-3dzcA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ehk | PRUNIN (Prunus dulcis) |
PF00190(Cupin_1) | 4 | VAL A 271PRO A 228GLY A 226TYR A 223 | None | 1.36A | 5x80A-3ehkA:undetectable5x80B-3ehkA:undetectable | 5x80A-3ehkA:13.455x80B-3ehkA:13.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gtd | FUMARATE HYDRATASECLASS II (Rickettsiaprowazekii) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 4 | VAL A 409PRO A 414GLY A 417TYR A 418 | None | 1.29A | 5x80A-3gtdA:undetectable5x80B-3gtdA:undetectable | 5x80A-3gtdA:19.205x80B-3gtdA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i5t | AMINOTRANSFERASE (Rhodobactersphaeroides) |
PF00202(Aminotran_3) | 4 | VAL A 204PRO A 237GLY A 239TYR A 240 | None | 1.23A | 5x80A-3i5tA:2.45x80B-3i5tA:2.7 | 5x80A-3i5tA:15.515x80B-3i5tA:15.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j2s | COAGULATION FACTORVIII LIGHT CHAIN (Homo sapiens) |
PF00754(F5_F8_type_C)PF07731(Cu-oxidase_2) | 4 | VAL B1933PRO B2024GLY B2026TYR B2017 | None | 1.40A | 5x80A-3j2sB:undetectable5x80B-3j2sB:undetectable | 5x80A-3j2sB:13.715x80B-3j2sB:13.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jq1 | SUSD SUPERFAMILYPROTEIN (Bacteroidesvulgatus) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 4 | VAL A 70ARG A 73GLY A 63TYR A 65 | None | 1.35A | 5x80A-3jq1A:undetectable5x80B-3jq1A:undetectable | 5x80A-3jq1A:15.645x80B-3jq1A:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k92 | NAD-SPECIFICGLUTAMATEDEHYDROGENASE (Bacillussubtilis) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | VAL A 424PRO A 35GLY A 36TYR A 34 | None | 1.14A | 5x80A-3k92A:undetectable5x80B-3k92A:undetectable | 5x80A-3k92A:16.215x80B-3k92A:16.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3krt | CROTONYL COAREDUCTASE (Streptomycescoelicolor) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | VAL A 408PRO A 54GLY A 402TYR A 406 | None | 1.08A | 5x80A-3krtA:undetectable5x80B-3krtA:undetectable | 5x80A-3krtA:20.355x80B-3krtA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kxw | SAFRAMYCIN MX1SYNTHETASE B (Legionellapneumophila) |
PF00501(AMP-binding) | 4 | VAL A 491PRO A 468GLY A 463TYR A 467 | None | 1.16A | 5x80A-3kxwA:undetectable5x80B-3kxwA:undetectable | 5x80A-3kxwA:14.095x80B-3kxwA:14.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l2k | EHPF (Pantoeaagglomerans) |
PF00501(AMP-binding) | 4 | VAL A 296ARG A 335GLY A 308TYR A 307 | None | 1.42A | 5x80A-3l2kA:undetectable5x80B-3l2kA:undetectable | 5x80A-3l2kA:18.035x80B-3l2kA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mog | PROBABLE3-HYDROXYBUTYRYL-COADEHYDROGENASE (Escherichiacoli) |
PF00725(3HCDH)PF02737(3HCDH_N) | 4 | VAL A 394PRO A 426GLY A 428TYR A 425 | None | 1.30A | 5x80A-3mogA:undetectable5x80B-3mogA:undetectable | 5x80A-3mogA:16.915x80B-3mogA:16.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3no4 | CREATININEAMIDOHYDROLASE (Nostocpunctiforme) |
PF02633(Creatininase) | 4 | VAL A 193PRO A 210GLY A 212TYR A 209 | None | 0.80A | 5x80A-3no4A:undetectable5x80B-3no4A:undetectable | 5x80A-3no4A:25.185x80B-3no4A:25.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o9p | PERIPLASMIC MUREINPEPTIDE-BINDINGPROTEIN (Escherichiacoli) |
PF00496(SBP_bac_5) | 4 | VAL A 386PRO A 356GLY A 352TYR A 351 | None | 1.12A | 5x80A-3o9pA:undetectable5x80B-3o9pA:undetectable | 5x80A-3o9pA:16.115x80B-3o9pA:16.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pjp | TRANSCRIPTIONELONGATION FACTORSPT6 ([Candida]glabrata) |
PF14633(SH2_2) | 4 | VAL A1426PRO A1424GLY A1415TYR A1423 | None | 1.34A | 5x80A-3pjpA:undetectable5x80B-3pjpA:undetectable | 5x80A-3pjpA:20.605x80B-3pjpA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sgz | HYDROXYACID OXIDASE2 (Rattusnorvegicus) |
PF01070(FMN_dh) | 4 | VAL A 281ARG A 282PRO A 303GLY A 301 | NoneFMN A 401 (-2.9A)FMN A 401 (-4.8A)FMN A 401 (-3.4A) | 1.05A | 5x80A-3sgzA:0.15x80B-3sgzA:0.2 | 5x80A-3sgzA:18.775x80B-3sgzA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uxf | FIMBRIAL SUBUNITTYPE 1 (Actinomycesoris) |
no annotation | 4 | VAL A 215PRO A 218GLY A 219TYR A 217 | None | 1.29A | 5x80A-3uxfA:undetectable5x80B-3uxfA:undetectable | 5x80A-3uxfA:16.975x80B-3uxfA:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uxf | FIMBRIAL SUBUNITTYPE 1 (Actinomycesoris) |
no annotation | 4 | VAL A 215PRO A 218GLY A 220TYR A 217 | None | 1.12A | 5x80A-3uxfA:undetectable5x80B-3uxfA:undetectable | 5x80A-3uxfA:16.975x80B-3uxfA:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v75 | OROTIDINE5'-PHOSPHATEDECARBOXYLASE (Streptomycesavermitilis) |
PF00215(OMPdecase) | 4 | VAL A 175PRO A 129GLY A 132TYR A 130 | None | 1.13A | 5x80A-3v75A:undetectable5x80B-3v75A:undetectable | 5x80A-3v75A:25.835x80B-3v75A:25.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v96 | STROMELYSIN-2 (Homo sapiens) |
PF00413(Peptidase_M10) | 4 | VAL B 143PRO B 145GLY B 263TYR B 262 | None | 1.44A | 5x80A-3v96B:undetectable5x80B-3v96B:undetectable | 5x80A-3v96B:19.655x80B-3v96B:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vi3 | INTEGRIN ALPHA-5 (Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2) | 4 | VAL A 252PRO A 183GLY A 190TYR A 230 | None | 1.42A | 5x80A-3vi3A:undetectable5x80B-3vi3A:undetectable | 5x80A-3vi3A:14.175x80B-3vi3A:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w95 | GENOME POLYPROTEIN (Enterovirus A) |
PF00947(Pico_P2A) | 4 | VAL A 84ARG A 93PRO A 91TYR A 90 | None | 1.21A | 5x80A-3w95A:undetectable5x80B-3w95A:undetectable | 5x80A-3w95A:27.425x80B-3w95A:27.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x17 | ENDOGLUCANASE (unculturedbacterium) |
no annotation | 4 | VAL B 487PRO B 529GLY B 527TYR B 547 | None | 1.30A | 5x80A-3x17B:undetectable5x80B-3x17B:undetectable | 5x80A-3x17B:16.255x80B-3x17B:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4avo | BETA-1,4-EXOCELLULASE (Thermobifidafusca) |
PF01341(Glyco_hydro_6) | 4 | VAL A 305PRO A 223GLY A 300TYR A 301 | None | 1.39A | 5x80A-4avoA:undetectable5x80B-4avoA:undetectable | 5x80A-4avoA:15.835x80B-4avoA:15.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bvx | METHIONINE--TRNALIGASE, CYTOPLASMIC (Homo sapiens) |
PF00043(GST_C) | 4 | VAL A 189PRO A 154GLY A 150TYR A 153 | None | 1.15A | 5x80A-4bvxA:undetectable5x80B-4bvxA:undetectable | 5x80A-4bvxA:23.215x80B-4bvxA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7v | TRANSKETOLASE (Lactobacillussalivarius) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | VAL A 10ARG A 14GLY A 34TYR A 252 | None | 1.11A | 5x80A-4c7vA:undetectable5x80B-4c7vA:undetectable | 5x80A-4c7vA:13.805x80B-4c7vA:13.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d4g | APNAA1 (Planktothrixagardhii) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | VAL A 152PRO A 83GLY A 58TYR A 81 | None | 1.44A | 5x80A-4d4gA:undetectable5x80B-4d4gA:undetectable | 5x80A-4d4gA:15.365x80B-4d4gA:15.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e1t | INVASIN (Yersiniapseudotuberculosis) |
PF11924(IAT_beta) | 4 | VAL A 386ARG A 229GLY A 270TYR A 248 | None | 0.95A | 5x80A-4e1tA:undetectable5x80B-4e1tA:undetectable | 5x80A-4e1tA:19.035x80B-4e1tA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hqn | SPOROZOITE SURFACEPROTEIN 2 (Plasmodiumvivax) |
PF00090(TSP_1)PF00092(VWA) | 4 | VAL A 64PRO A 123GLY A 56TYR A 57 | None | 1.25A | 5x80A-4hqnA:undetectable5x80B-4hqnA:undetectable | 5x80A-4hqnA:17.835x80B-4hqnA:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4igl | YENC2 (Yersiniaentomophaga) |
no annotation | 4 | ARG B 411PRO B 612GLY B 614TYR B 611 | None | 1.03A | 5x80A-4iglB:undetectable5x80B-4iglB:undetectable | 5x80A-4iglB:14.245x80B-4iglB:14.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iug | BETA-GALACTOSIDASE A (Aspergillusoryzae) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 4 | VAL A 319PRO A 261GLY A 263TYR A 260 | NoneNoneNoneGAL A1130 (-4.5A) | 1.00A | 5x80A-4iugA:undetectable5x80B-4iugA:undetectable | 5x80A-4iugA:10.465x80B-4iugA:10.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mg3 | PROTEASE 2A (Enterovirus A) |
PF00947(Pico_P2A) | 4 | VAL A 84ARG A 93PRO A 91TYR A 90 | TRS A 203 (-3.9A)NoneNoneNone | 1.35A | 5x80A-4mg3A:undetectable5x80B-4mg3A:undetectable | 5x80A-4mg3A:22.865x80B-4mg3A:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mru | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF12741(SusD-like) | 4 | VAL A 421PRO A 401GLY A 293TYR A 290 | None | 1.43A | 5x80A-4mruA:undetectable5x80B-4mruA:undetectable | 5x80A-4mruA:14.755x80B-4mruA:14.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n2c | PROTEIN-ARGININEDEIMINASE TYPE-2 (Homo sapiens) |
PF03068(PAD)PF08526(PAD_N)PF08527(PAD_M) | 4 | VAL A 456PRO A 425GLY A 427TYR A 424 | None | 1.20A | 5x80A-4n2cA:undetectable5x80B-4n2cA:undetectable | 5x80A-4n2cA:13.505x80B-4n2cA:13.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n75 | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMA (Escherichiacoli) |
PF01103(Bac_surface_Ag) | 4 | VAL A 456PRO A 476GLY A 453TYR A 454 | None | 1.37A | 5x80A-4n75A:undetectable5x80B-4n75A:undetectable | 5x80A-4n75A:18.675x80B-4n75A:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o96 | TYPE III EFFECTORPROTEIN KINASE (Escherichiacoli) |
no annotation | 4 | VAL A 167PRO A 145GLY A 146TYR A 158 | GOL A 401 (-4.7A)NoneNoneNone | 1.43A | 5x80A-4o96A:undetectable5x80B-4o96A:undetectable | 5x80A-4o96A:21.115x80B-4o96A:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o9x | TCDB2, TCCC3 (Photorhabdusluminescens) |
PF03534(SpvB)PF12255(TcdB_toxin_midC)PF12256(TcdB_toxin_midN) | 4 | ARG A1911PRO A2113GLY A2115TYR A2112 | None | 1.05A | 5x80A-4o9xA:undetectable5x80B-4o9xA:undetectable | 5x80A-4o9xA:6.195x80B-4o9xA:6.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ozu | CORONIN (Toxoplasmagondii) |
PF00400(WD40)PF08953(DUF1899)PF16300(WD40_4) | 4 | VAL A 341PRO A 68GLY A 65TYR A 22 | None | 1.18A | 5x80A-4ozuA:undetectable5x80B-4ozuA:undetectable | 5x80A-4ozuA:17.015x80B-4ozuA:17.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p3y | THIOL:DISULFIDEINTERCHANGE PROTEIN (Acinetobacterbaumannii) |
PF01323(DSBA) | 4 | VAL B 83ARG B 86GLY B 116TYR B 115 | None | 1.39A | 5x80A-4p3yB:undetectable5x80B-4p3yB:undetectable | 5x80A-4p3yB:19.695x80B-4p3yB:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qx8 | LYSINE-SPECIFICDEMETHYLASE 2A (Mus musculus) |
PF02373(JmjC) | 4 | VAL A 320ARG A 325GLY A 216TYR A 312 | None | 1.35A | 5x80A-4qx8A:undetectable5x80B-4qx8A:undetectable | 5x80A-4qx8A:18.515x80B-4qx8A:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4um8 | INTEGRIN ALPHA-V (Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2) | 4 | VAL A 243PRO A 174GLY A 181TYR A 221 | None | 1.21A | 5x80A-4um8A:undetectable5x80B-4um8A:undetectable | 5x80A-4um8A:12.045x80B-4um8A:12.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wk4 | INTEGRIN ALPHA-5 (Homo sapiens) |
PF01839(FG-GAP) | 4 | VAL A 252PRO A 183GLY A 190TYR A 230 | None | 1.35A | 5x80A-4wk4A:undetectable5x80B-4wk4A:undetectable | 5x80A-4wk4A:17.385x80B-4wk4A:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4woe | TAUROCYAMINE KINASE (Schistosomamansoni) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 4 | VAL A 487ARG A 489GLY A 636TYR A 627 | None | 1.26A | 5x80A-4woeA:undetectable5x80B-4woeA:undetectable | 5x80A-4woeA:12.675x80B-4woeA:12.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wui | N-(5'-PHOSPHORIBOSYL)ANTHRANILATEISOMERASE (Jonesiadenitrificans) |
PF00697(PRAI) | 4 | VAL A 114ARG A 102GLY A 118TYR A 117 | None | 1.34A | 5x80A-4wuiA:undetectable5x80B-4wuiA:undetectable | 5x80A-4wuiA:26.205x80B-4wuiA:26.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wzb | NITROGENASEMOLYBDENUM-IRONPROTEIN ALPHA CHAIN (Azotobactervinelandii) |
PF00148(Oxidored_nitro) | 4 | ARG A 96PRO A 74GLY A 255TYR A 229 | ICS A1496 (-4.0A)NoneNoneICS A1496 (-4.1A) | 1.14A | 5x80A-4wzbA:undetectable5x80B-4wzbA:undetectable | 5x80A-4wzbA:17.045x80B-4wzbA:17.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c92 | KELCHDOMAIN-CONTAININGPROTEIN (Colletotrichumgraminicola) |
PF01344(Kelch_1)PF09118(DUF1929) | 4 | VAL A 293ARG A 278GLY A 274TYR A 276 | None | 1.18A | 5x80A-5c92A:undetectable5x80B-5c92A:undetectable | 5x80A-5c92A:15.375x80B-5c92A:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ccx | TRNA(ADENINE(58)-N(1))-METHYLTRANSFERASENON-CATALYTICSUBUNIT TRM6 (Homo sapiens) |
PF04189(Gcd10p) | 4 | VAL B 237PRO B 232GLY B 233TYR B 231 | A N 43 ( 4.8A)NoneNoneNone | 1.42A | 5x80A-5ccxB:undetectable5x80B-5ccxB:undetectable | 5x80A-5ccxB:14.895x80B-5ccxB:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5do7 | ATP-BINDING CASSETTESUB-FAMILY G MEMBER5 (Homo sapiens) |
PF00005(ABC_tran)PF01061(ABC2_membrane) | 4 | VAL A 534PRO A 431GLY A 434TYR A 432 | None | 1.13A | 5x80A-5do7A:0.25x80B-5do7A:0.0 | 5x80A-5do7A:13.245x80B-5do7A:13.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5esx | PURINE/PYRIMIDINEPHOSPHORIBOSYLTRANSFERASE (Legionellapneumophila) |
PF00156(Pribosyltran) | 4 | VAL A 135PRO A 55GLY A 165TYR A 164 | None | 1.10A | 5x80A-5esxA:undetectable5x80B-5esxA:undetectable | 5x80A-5esxA:22.445x80B-5esxA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ewy | PUTATIVEADP-RIBOSYLTRANSFERASE SCABIN (Streptomycesscabiei) |
no annotation | 4 | VAL A 59PRO A 114GLY A 165TYR A 115 | None | 1.45A | 5x80A-5ewyA:undetectable5x80B-5ewyA:undetectable | 5x80A-5ewyA:19.295x80B-5ewyA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fr8 | TONB-DEPENDENTSIDEROPHORE RECEPTOR (Acinetobacterbaumannii) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | VAL A 672PRO A 616GLY A 642TYR A 641 | None | 1.37A | 5x80A-5fr8A:undetectable5x80B-5fr8A:undetectable | 5x80A-5fr8A:11.485x80B-5fr8A:11.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hp5 | PROTEIN-ARGININEDEIMINASE TYPE-1 (Homo sapiens) |
PF03068(PAD)PF08526(PAD_N)PF08527(PAD_M) | 4 | VAL A 457PRO A 426GLY A 428TYR A 425 | None | 1.17A | 5x80A-5hp5A:undetectable5x80B-5hp5A:undetectable | 5x80A-5hp5A:15.775x80B-5hp5A:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hx0 | UNCHARACTERIZEDPROTEIN DFER_1899 (Dyadobacterfermentans) |
PF13088(BNR_2) | 4 | VAL A 353PRO A 331GLY A 333TYR A 327 | None | 1.34A | 5x80A-5hx0A:undetectable5x80B-5hx0A:undetectable | 5x80A-5hx0A:18.425x80B-5hx0A:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hxw | L-AMINO ACIDDEAMINASE (Proteusvulgaris) |
PF01266(DAO) | 4 | VAL A 236PRO A 428GLY A 429TYR A 427 | None | 1.39A | 5x80A-5hxwA:undetectable5x80B-5hxwA:undetectable | 5x80A-5hxwA:16.375x80B-5hxwA:16.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j78 | ACETALDEHYDEDEHYDROGENASE(ACETYLATING) (Parageobacillusthermoglucosidasius) |
PF00171(Aldedh) | 4 | VAL A 330PRO A 366GLY A 325TYR A 269 | None | 1.09A | 5x80A-5j78A:0.55x80B-5j78A:0.7 | 5x80A-5j78A:17.425x80B-5j78A:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jrl | DIPEPTIDYLAMINOPEPTIDASES/ACYLAMINOACYL-PEPTIDASES-LIKE PROTEIN (Sphingopyxisalaskensis) |
PF00326(Peptidase_S9) | 4 | VAL A 626ARG A 721PRO A 719GLY A 652 | None | 1.10A | 5x80A-5jrlA:undetectable5x80B-5jrlA:undetectable | 5x80A-5jrlA:15.145x80B-5jrlA:15.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l3z | POLYKETIDEKETOREDUCTASE SIMC7 (Streptomycesantibioticus) |
PF13460(NAD_binding_10) | 4 | ARG A 215PRO A 156GLY A 157TYR A 155 | None | 0.92A | 5x80A-5l3zA:undetectable5x80B-5l3zA:undetectable | 5x80A-5l3zA:26.715x80B-5l3zA:26.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m11 | IMMUNOREACTIVE 84KDANTIGEN PG93 (Porphyromonasgingivalis) |
no annotation | 4 | VAL A 774PRO A 696GLY A 706TYR A 703 | None | 1.43A | 5x80A-5m11A:undetectable5x80B-5m11A:undetectable | 5x80A-5m11A:11.815x80B-5m11A:11.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5neu | INTEGRIN ALPHA-V (Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2) | 4 | VAL A 243PRO A 174GLY A 181TYR A 221 | None | 1.13A | 5x80A-5neuA:undetectable5x80B-5neuA:undetectable | 5x80A-5neuA:14.825x80B-5neuA:14.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tcb | PELA (Pseudomonasaeruginosa) |
PF03537(Glyco_hydro_114) | 4 | VAL A 72PRO A 93GLY A 156TYR A 154 | None | 1.38A | 5x80A-5tcbA:undetectable5x80B-5tcbA:undetectable | 5x80A-5tcbA:28.995x80B-5tcbA:28.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vi6 | HISTONE DEACETYLASE8 (Homo sapiens) |
PF00850(Hist_deacetyl) | 4 | VAL A 345ARG A 313GLY A 341TYR A 340 | None | 1.39A | 5x80A-5vi6A:undetectable5x80B-5vi6A:undetectable | 5x80A-5vi6A:18.385x80B-5vi6A:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bgz | LYSINE-SPECIFICDEMETHYLASE 5A,LINKED KDM5A JMJDOMAIN (Homo sapiens) |
no annotation | 4 | VAL A 550PRO A 507GLY A 505TYR A 553 | None | 1.44A | 5x80A-6bgzA:undetectable5x80B-6bgzA:undetectable | 5x80A-6bgzA:21.745x80B-6bgzA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6es9 | ACYL-COADEHYDROGENASE (Paracoccusdenitrificans) |
no annotation | 4 | VAL A 524ARG A 523GLY A 242TYR A 243 | None | 1.35A | 5x80A-6es9A:0.85x80B-6es9A:0.9 | 5x80A-6es9A:23.905x80B-6es9A:23.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f42 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC1 (Saccharomycescerevisiae) |
no annotation | 4 | VAL A 266ARG A 269PRO A 264GLY A 82 | None | 1.45A | 5x80A-6f42A:undetectable5x80B-6f42A:undetectable | 5x80A-6f42A:20.755x80B-6f42A:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gmb | HYDROXYACID OXIDASE1 (Homo sapiens) |
no annotation | 4 | VAL A 294ARG A 295PRO A 316GLY A 314 | NoneFMN A 506 ( 2.6A)PG4 A 503 ( 3.7A)FMN A 506 (-3.4A) | 1.06A | 5x80A-6gmbA:undetectable5x80B-6gmbA:0.0 | 5x80A-6gmbA:18.455x80B-6gmbA:18.45 |