SIMILAR PATTERNS OF AMINO ACIDS FOR 5X7Z_A_BHAA201_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13pk 3-PHOSPHOGLYCERATE
KINASE

(Trypanosoma
brucei) 		PF00162
(PGK) 		4 LEU A  20
VAL A  58
LEU A 131
VAL A 120
 None
 0.92A 5x7zA-13pkA:
0.0		 5x7zA-13pkA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ao5 GLANDULAR
KALLIKREIN-13

(Mus musculus) 		PF00089
(Trypsin) 		4 VAL A  31
LEU A  46
ARG A  83
VAL A  66
 None
 0.95A 5x7zA-1ao5A:
undetectable		 5x7zA-1ao5A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c0a ASPARTYL TRNA
SYNTHETASE

(Escherichia
coli) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		4 LEU A  20
ARG A   2
VAL A  18
VAL A  75
 None
 0.86A 5x7zA-1c0aA:
0.6		 5x7zA-1c0aA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4o DNA NUCLEOTIDE
EXCISION REPAIR
ENZYME UVRB

(Thermus
thermophilus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF12344
(UvrB) 		4 LEU A 332
VAL A 330
LEU A  58
VAL A 381
 None
 0.95A 5x7zA-1c4oA:
0.0		 5x7zA-1c4oA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f7u ARGINYL-TRNA
SYNTHETASE

(Saccharomyces
cerevisiae) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		4 LEU A 598
VAL A 550
LEU A 554
VAL A 537
 None
 0.96A 5x7zA-1f7uA:
2.0		 5x7zA-1f7uA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fad PROTEIN (FADD
PROTEIN)

(Mus musculus) 		PF00531
(Death) 		4 ARG A 166
VAL A 173
ARG A 114
VAL A 108
 None
 0.95A 5x7zA-1fadA:
0.0		 5x7zA-1fadA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1glv GLUTATHIONE SYNTHASE

(Escherichia
coli) 		PF02951
(GSH-S_N)
PF02955
(GSH-S_ATP) 		4 ARG A 312
VAL A  82
LEU A 313
ARG A  31
 None
 0.91A 5x7zA-1glvA:
0.0		 5x7zA-1glvA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gzv GLUCOSE-6-PHOSPHATE
ISOMERASE

(Sus scrofa) 		PF00342
(PGI) 		4 LEU A 311
VAL A 317
LEU A 321
VAL A 499
 None
 0.97A 5x7zA-1gzvA:
0.0		 5x7zA-1gzvA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kol FORMALDEHYDE
DEHYDROGENASE

(Pseudomonas
putida) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 242
VAL A 289
LEU A 286
VAL A 255
 SO4  A1003 (-4.5A)
None
None
None
 0.98A 5x7zA-1kolA:
undetectable		 5x7zA-1kolA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l0w ASPARTYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		4 LEU A  97
VAL A  69
ARG A  28
VAL A  25
 None
 0.97A 5x7zA-1l0wA:
0.5		 5x7zA-1l0wA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nf9 PHENAZINE
BIOSYNTHESIS PROTEIN
PHZD

(Pseudomonas
aeruginosa) 		PF00857
(Isochorismatase) 		4 LEU A  62
VAL A 205
LEU A  27
VAL A 200
 None
 0.97A 5x7zA-1nf9A:
undetectable		 5x7zA-1nf9A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o6e CAPSID PROTEIN P40

(Human
gammaherpesvirus
4) 		PF00716
(Peptidase_S21) 		4 LEU A 201
VAL A  46
LEU A 112
VAL A  54
 None
 0.97A 5x7zA-1o6eA:
undetectable		 5x7zA-1o6eA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oxx ABC TRANSPORTER, ATP
BINDING PROTEIN

(Sulfolobus
solfataricus) 		PF00005
(ABC_tran) 		4 LEU K 219
VAL K  24
LEU K  21
VAL K   6
 IOD  K1920 ( 4.1A)
IOD  K1920 ( 4.6A)
None
None
 0.89A 5x7zA-1oxxK:
undetectable		 5x7zA-1oxxK:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5d P450 EPOXIDASE

(Sorangium
cellulosum) 		PF00067
(p450) 		4 LEU A 413
VAL A 411
LEU A 271
VAL A 145
 None
 0.94A 5x7zA-1q5dA:
1.6		 5x7zA-1q5dA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rqg METHIONYL-TRNA
SYNTHETASE

(Pyrococcus
abyssi) 		PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g) 		4 LEU A 544
VAL A 404
LEU A 408
VAL A 497
 None
 0.94A 5x7zA-1rqgA:
undetectable		 5x7zA-1rqgA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s21 ORF2

(Pseudomonas
savastanoi) 		PF09143
(AvrPphF-ORF-2) 		4 LEU A 161
ARG A 160
VAL A  70
VAL A 136
 None
 0.90A 5x7zA-1s21A:
undetectable		 5x7zA-1s21A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s8e EXONUCLEASE PUTATIVE

(Pyrococcus
furiosus) 		PF00149
(Metallophos) 		4 LEU A 192
VAL A 176
LEU A 204
VAL A 179
 None
 0.98A 5x7zA-1s8eA:
undetectable		 5x7zA-1s8eA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t6p PHENYLALANINE
AMMONIA-LYASE

(Rhodotorula
toruloides) 		PF00221
(Lyase_aromatic) 		4 ARG A 172
VAL A 187
LEU A 191
VAL A 258
 None
 0.88A 5x7zA-1t6pA:
0.4		 5x7zA-1t6pA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE

(Thermus
thermophilus) 		PF00590
(TP_methylase) 		4 LEU A 215
VAL A 157
LEU A 129
VAL A 140
 None
 0.91A 5x7zA-1ve2A:
undetectable		 5x7zA-1ve2A:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w9c CRM1 PROTEIN

(Homo sapiens) 		PF08767
(CRM1_C) 		4 LEU A 780
VAL A 784
LEU A 785
VAL A 800
 None
 0.96A 5x7zA-1w9cA:
undetectable		 5x7zA-1w9cA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wws HYPOTHETICAL PROTEIN
TTHA1479

(Thermus
thermophilus) 		PF09123
(DUF1931) 		4 LEU A  89
ARG A  33
VAL A  85
LEU A   2
 None
 0.93A 5x7zA-1wwsA:
undetectable		 5x7zA-1wwsA:
27.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9u PUTATIVE IRON
BINDING PROTEIN

(Bordetella
pertussis) 		PF13343
(SBP_bac_6) 		4 LEU A 171
VAL A 167
LEU A 125
ARG A 107
 None
 0.91A 5x7zA-1y9uA:
undetectable		 5x7zA-1y9uA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yle ARGININE
N-SUCCINYLTRANSFERAS
E, ALPHA CHAIN

(Pseudomonas
aeruginosa) 		PF04958
(AstA) 		4 LEU A 335
VAL A 333
LEU A 325
VAL A 278
 None
 0.95A 5x7zA-1yleA:
undetectable		 5x7zA-1yleA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a87 THIOREDOXIN
REDUCTASE

(Mycobacterium
tuberculosis) 		PF07992
(Pyr_redox_2) 		4 LEU A 256
VAL A  96
LEU A  98
VAL A 105
 FAD  A 348 (-4.7A)
None
None
None
 0.93A 5x7zA-2a87A:
undetectable		 5x7zA-2a87A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4a MALATE DEHYDROGENASE

(Aeropyrum
pernix) 		no annotation 4 LEU B 190
VAL B 185
LEU B 157
VAL B 164
 None
 0.98A 5x7zA-2d4aB:
undetectable		 5x7zA-2d4aB:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2du3 O-PHOSPHOSERYL-TRNA
SYNTHETASE

(Archaeoglobus
fulgidus) 		PF01409
(tRNA-synt_2d) 		4 LEU A 128
VAL A 152
LEU A 148
VAL A 123
 None
 0.97A 5x7zA-2du3A:
0.8		 5x7zA-2du3A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e1m L-GLUTAMATE OXIDASE
L-GLUTAMATE OXIDASE

(Streptomyces
sp. X-119-6;
Streptomyces
sp. X-119-6) 		PF01593
(Amino_oxidase)
PF01593
(Amino_oxidase) 		4 LEU A  76
VAL A  72
LEU A 340
VAL C 658
 None
 0.81A 5x7zA-2e1mA:
undetectable		 5x7zA-2e1mA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ei9 NON-LTR
RETROTRANSPOSON
R1BMKS ORF2 PROTEIN

(Bombyx mori) 		PF14529
(Exo_endo_phos_2) 		4 LEU A  52
VAL A  42
LEU A  18
VAL A  40
 None
 0.96A 5x7zA-2ei9A:
undetectable		 5x7zA-2ei9A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g5g PUTATIVE LIPOPROTEIN

(Campylobacter
jejuni) 		PF04187
(Cofac_haem_bdg) 		4 LEU X  79
VAL X  77
LEU X 213
VAL X 127
 None
 0.94A 5x7zA-2g5gX:
undetectable		 5x7zA-2g5gX:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmi UBIQUITIN-CONJUGATIN
G ENZYME VARIANT
MMS2

(Saccharomyces
cerevisiae) 		PF00179
(UQ_con) 		4 LEU B  60
VAL B  75
LEU B 112
VAL B  93
 None
 0.98A 5x7zA-2gmiB:
undetectable		 5x7zA-2gmiB:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hig 6-PHOSPHO-1-FRUCTOKI
NASE

(Trypanosoma
brucei) 		PF00365
(PFK) 		4 LEU A 309
VAL A 357
LEU A 353
VAL A 373
 None
 0.94A 5x7zA-2higA:
undetectable		 5x7zA-2higA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnh DNA POLYMERASE III
ALPHA SUBUNIT

(Escherichia
coli) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		4 LEU A 168
VAL A 139
LEU A 143
VAL A 155
 None
 0.95A 5x7zA-2hnhA:
undetectable		 5x7zA-2hnhA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iip NICOTINAMIDE
N-METHYLTRANSFERASE

(Homo sapiens) 		PF01234
(NNMT_PNMT_TEMT) 		5 LEU A 131
ARG A 132
VAL A 135
LEU A  98
VAL A  83
 None
 1.29A 5x7zA-2iipA:
undetectable		 5x7zA-2iipA:
27.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inv INSULIN
FRUCTOTRANSFERASE

(Bacillus sp.
snu-7) 		no annotation 4 LEU A 227
VAL A 229
LEU A 235
VAL A 206
 None
 0.84A 5x7zA-2invA:
undetectable		 5x7zA-2invA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jvc UBIQUITIN_LIKE
PROTEIN

(-) 		PF00240
(ubiquitin) 		4 LEU A  76
ARG A  47
LEU A  48
VAL A  10
 None
 0.96A 5x7zA-2jvcA:
undetectable		 5x7zA-2jvcA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m26 HCF C-TERMINAL CHAIN
1

(Mus musculus) 		no annotation 4 LEU A  24
VAL A  77
LEU A  82
VAL A  67
 None
 0.93A 5x7zA-2m26A:
undetectable		 5x7zA-2m26A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nzi TITIN

(Homo sapiens) 		PF00041
(fn3)
PF07679
(I-set) 		4 LEU A 214
VAL A 255
LEU A 258
VAL A 245
 None
 0.85A 5x7zA-2nziA:
undetectable		 5x7zA-2nziA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o16 ACETOIN UTILIZATION
PROTEIN ACUB,
PUTATIVE

(Vibrio cholerae) 		PF00571
(CBS) 		4 LEU A  73
VAL A  68
LEU A  96
VAL A  55
 None
 0.95A 5x7zA-2o16A:
undetectable		 5x7zA-2o16A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ogp PARTITIONING-DEFECTI
VE 3 HOMOLOG

(Rattus
norvegicus) 		PF00595
(PDZ) 		4 LEU A  74
VAL A  77
LEU A  93
VAL A 103
 None
 0.98A 5x7zA-2ogpA:
undetectable		 5x7zA-2ogpA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okx RHAMNOSIDASE B

(Bacillus sp.
GL1) 		PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		4 LEU A 337
VAL A 246
LEU A 225
VAL A 303
 None
 0.88A 5x7zA-2okxA:
undetectable		 5x7zA-2okxA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oqr SENSORY TRANSDUCTION
PROTEIN REGX3

(Mycobacterium
tuberculosis) 		PF00072
(Response_reg)
PF00486
(Trans_reg_C) 		4 LEU A  51
VAL A  49
LEU A   5
ARG A  70
 None
 0.90A 5x7zA-2oqrA:
3.7		 5x7zA-2oqrA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ot9 HYPOTHETICAL PROTEIN

(Pseudomonas
syringae group
genomosp. 3) 		PF07152
(YaeQ) 		4 LEU A 105
VAL A 132
LEU A 137
VAL A 170
 None
 0.95A 5x7zA-2ot9A:
undetectable		 5x7zA-2ot9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rgy TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Paraburkholderia
phymatum) 		PF13377
(Peripla_BP_3) 		4 VAL A 137
LEU A 163
ARG A 175
VAL A 150
 None
 0.98A 5x7zA-2rgyA:
undetectable		 5x7zA-2rgyA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rir DIPICOLINATE
SYNTHASE, A CHAIN

(Bacillus
subtilis) 		PF01262
(AlaDh_PNT_C)
PF16924
(DpaA_N) 		4 LEU A 198
VAL A 182
LEU A 162
VAL A 159
 None
 0.91A 5x7zA-2rirA:
undetectable		 5x7zA-2rirA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9k UNCHARACTERIZED
PROTEIN FLJ32312

(Homo sapiens) 		no annotation 4 ARG A 176
VAL A 163
LEU A 174
VAL A  11
 None
 0.89A 5x7zA-2v9kA:
undetectable		 5x7zA-2v9kA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wul GLUTAREDOXIN RELATED
PROTEIN 5

(Homo sapiens) 		PF00462
(Glutaredoxin) 		4 LEU A 125
VAL A 112
LEU A 114
VAL A  56
 None
 0.98A 5x7zA-2wulA:
undetectable		 5x7zA-2wulA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x30 PHOSPHORIBOSYL
ISOMERASE A

(Streptomyces
coelicolor) 		PF00977
(His_biosynth) 		4 LEU A   6
VAL A 221
LEU A 225
VAL A 199
 None
SO4  A1242 ( 4.8A)
None
None
 0.97A 5x7zA-2x30A:
undetectable		 5x7zA-2x30A:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xw7 DIHYDROFOLATE
REDUCTASE

(Mycolicibacterium
smegmatis) 		PF01872
(RibD_C) 		4 LEU A  73
VAL A  49
LEU A 100
VAL A 111
 NDP  A1173 (-4.0A)
None
None
None
 0.95A 5x7zA-2xw7A:
undetectable		 5x7zA-2xw7A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y89 PHOSPHORIBOSYL
ISOMERASE A

(Mycobacterium
tuberculosis) 		PF00977
(His_biosynth) 		4 LEU A   6
VAL A 225
LEU A 229
VAL A 203
 None
 0.95A 5x7zA-2y89A:
undetectable		 5x7zA-2y89A:
26.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yg8 DNA-3-METHYLADENINE
GLYCOSIDASE II,
PUTATIVE

(Deinococcus
radiodurans) 		PF00730
(HhH-GPD) 		4 LEU A 111
VAL A 119
LEU A  98
VAL A  66
 None
 0.97A 5x7zA-2yg8A:
undetectable		 5x7zA-2yg8A:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zws NEUTRAL CERAMIDASE

(Pseudomonas
aeruginosa) 		PF04734
(Ceramidase_alk)
PF17048
(Ceramidse_alk_C) 		4 LEU A  78
VAL A  91
LEU A  93
VAL A  57
 None
 0.95A 5x7zA-2zwsA:
undetectable		 5x7zA-2zwsA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afo NADH KINASE POS5

(Saccharomyces
cerevisiae) 		PF01513
(NAD_kinase) 		4 LEU A  67
VAL A  70
LEU A  92
VAL A 145
 None
 0.90A 5x7zA-3afoA:
undetectable		 5x7zA-3afoA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqu AT4G19810

(Arabidopsis
thaliana) 		PF00704
(Glyco_hydro_18) 		4 LEU A 176
VAL A 179
LEU A 223
VAL A 156
 None
 0.91A 5x7zA-3aquA:
undetectable		 5x7zA-3aquA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cl3 ORF K13

(Human
gammaherpesvirus
8) 		PF01335
(DED) 		4 LEU A  14
ARG A  19
VAL A  22
LEU A  23
 None
 0.95A 5x7zA-3cl3A:
undetectable		 5x7zA-3cl3A:
26.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3co8 ALANINE RACEMASE

(Oenococcus oeni) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 LEU A 123
VAL A 125
LEU A 151
VAL A 105
 None
 0.90A 5x7zA-3co8A:
undetectable		 5x7zA-3co8A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3w L-XYLULOSE REDUCTASE

(Homo sapiens) 		PF13561
(adh_short_C2) 		4 LEU B  11
VAL B  37
LEU B  61
VAL B  57
 None
None
NAP  B1245 (-3.8A)
None
 0.94A 5x7zA-3d3wB:
undetectable		 5x7zA-3d3wB:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gvh MALATE DEHYDROGENASE

(Brucella
abortus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 LEU A 136
VAL A 116
LEU A 130
VAL A  75
 None
 0.97A 5x7zA-3gvhA:
undetectable		 5x7zA-3gvhA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gz8 MUTT/NUDIX FAMILY
PROTEIN

(Shewanella
oneidensis) 		PF00293
(NUDIX) 		4 LEU A 130
VAL A  36
LEU A  38
VAL A  25
 None
 0.93A 5x7zA-3gz8A:
undetectable		 5x7zA-3gz8A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2z MANNITOL-1-PHOSPHATE
5-DEHYDROGENASE

(Shigella
flexneri) 		PF01232
(Mannitol_dh)
PF08125
(Mannitol_dh_C) 		4 LEU A  40
VAL A  63
LEU A  27
VAL A  60
 None
 0.95A 5x7zA-3h2zA:
undetectable		 5x7zA-3h2zA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hd6 AMMONIUM TRANSPORTER
RH TYPE C

(Homo sapiens) 		PF00909
(Ammonium_transp) 		4 LEU A 151
VAL A 146
LEU A 416
VAL A 142
 None
 0.95A 5x7zA-3hd6A:
0.2		 5x7zA-3hd6A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i70 AGRIN

(Gallus gallus) 		PF03146
(NtA) 		4 LEU A 103
VAL A  63
LEU A  57
VAL A  41
 None
 0.98A 5x7zA-3i70A:
undetectable		 5x7zA-3i70A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ijl MUCONATE
CYCLOISOMERASE

(Bacteroides
thetaiotaomicron) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 106
VAL A 109
LEU A 111
VAL A 127
 None
 0.91A 5x7zA-3ijlA:
undetectable		 5x7zA-3ijlA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ist GLUTAMATE RACEMASE

(Listeria
monocytogenes) 		PF01177
(Asp_Glu_race) 		5 LEU A  15
ARG A  19
VAL A  18
LEU A  22
VAL A  30
 None
 1.35A 5x7zA-3istA:
undetectable		 5x7zA-3istA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jsa HOMOSERINE
DEHYDROGENASE

(Thermoplasma
volcanium) 		PF00742
(Homoserine_dh)
PF03447
(NAD_binding_3) 		4 LEU A   6
VAL A  88
LEU A  18
VAL A 115
 None
 0.91A 5x7zA-3jsaA:
undetectable		 5x7zA-3jsaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kqf ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Bacillus
anthracis) 		PF00378
(ECH_1) 		4 LEU A  98
VAL A  54
LEU A  56
VAL A  17
 None
 0.89A 5x7zA-3kqfA:
undetectable		 5x7zA-3kqfA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l6d PUTATIVE
OXIDOREDUCTASE

(Pseudomonas
putida) 		PF03446
(NAD_binding_2) 		4 LEU A  73
VAL A  82
LEU A  83
VAL A  59
 None
 0.97A 5x7zA-3l6dA:
undetectable		 5x7zA-3l6dA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcf DIPHOSPHOINOSITOL
POLYPHOSPHATE
PHOSPHOHYDROLASE
3-ALPHA

(Homo sapiens) 		PF00293
(NUDIX) 		4 LEU A  35
VAL A  33
LEU A  23
VAL A 122
 None
 0.87A 5x7zA-3mcfA:
undetectable		 5x7zA-3mcfA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjg PLATELET-DERIVED
GROWTH FACTOR
SUBUNIT B

(Homo sapiens) 		PF00341
(PDGF)
PF04692
(PDGF_N) 		4 LEU A  91
VAL A  89
LEU A  29
VAL A  72
 None
 0.79A 5x7zA-3mjgA:
undetectable		 5x7zA-3mjgA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6r PROPIONYL-COA
CARBOXYLASE, ALPHA
SUBUNIT

(Ruegeria
pomeroyi) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 VAL A 139
LEU A  67
ARG A 132
VAL A 161
 None
 0.97A 5x7zA-3n6rA:
undetectable		 5x7zA-3n6rA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntd FAD-DEPENDENT
PYRIDINE
NUCLEOTIDE-DISULPHID
E OXIDOREDUCTASE

(Shewanella
loihica) 		PF00581
(Rhodanese)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 244
VAL A 218
LEU A 215
VAL A 125
 None
 0.88A 5x7zA-3ntdA:
undetectable		 5x7zA-3ntdA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pco PHENYLALANYL-TRNA
SYNTHETASE, ALPHA
SUBUNIT

(Escherichia
coli) 		PF01409
(tRNA-synt_2d)
PF02912
(Phe_tRNA-synt_N) 		4 LEU A 270
VAL A 269
LEU A 302
VAL A 259
 None
 0.87A 5x7zA-3pcoA:
undetectable		 5x7zA-3pcoA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q64 MLL3774 PROTEIN

(Mesorhizobium
loti) 		PF08327
(AHSA1) 		4 LEU A  28
VAL A  24
LEU A 150
ARG A  15
 None
 0.84A 5x7zA-3q64A:
undetectable		 5x7zA-3q64A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qy2 CYCLIN-DEPENDENT
KINASES REGULATORY
SUBUNIT

(Saccharomyces
cerevisiae) 		PF01111
(CKS) 		4 LEU A  13
ARG A  18
VAL A  21
LEU A  22
 None
 0.93A 5x7zA-3qy2A:
undetectable		 5x7zA-3qy2A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rft URONATE
DEHYDROGENASE

(Agrobacterium
fabrum) 		PF01370
(Epimerase) 		4 LEU A  23
VAL A  69
LEU A  71
VAL A 107
 None
 0.88A 5x7zA-3rftA:
undetectable		 5x7zA-3rftA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3roh LEUCOTOXIN LUKEV

(Staphylococcus
aureus) 		PF07968
(Leukocidin) 		4 LEU A  74
VAL A  76
LEU A 112
VAL A  59
 None
 0.87A 5x7zA-3rohA:
undetectable		 5x7zA-3rohA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rr2 CYSTEINE SYNTHASE

(Mycobacterium
marinum) 		PF00291
(PALP) 		4 LEU A 292
VAL A 290
ARG A 275
VAL A  30
 None
 0.90A 5x7zA-3rr2A:
undetectable		 5x7zA-3rr2A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rxz POLYSACCHARIDE
DEACETYLASE

(Mycolicibacterium
smegmatis) 		PF01522
(Polysacc_deac_1) 		4 LEU A 162
VAL A 184
LEU A 186
VAL A 277
 None
 0.98A 5x7zA-3rxzA:
undetectable		 5x7zA-3rxzA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s1s RESTRICTION
ENDONUCLEASE BPUSI

(Bacillus
pumilus) 		PF02384
(N6_Mtase)
PF15516
(BpuSI_N) 		4 LEU A 470
ARG A 481
LEU A 568
VAL A 525
 None
 0.88A 5x7zA-3s1sA:
undetectable		 5x7zA-3s1sA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s2j DIPEPTIDASE

(Streptomyces
coelicolor) 		PF01244
(Peptidase_M19) 		4 LEU A 169
ARG A 174
VAL A 177
VAL A 187
 None
 0.90A 5x7zA-3s2jA:
undetectable		 5x7zA-3s2jA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfw DIHYDROPYRIMIDINASE

(Brevibacillus
agri) 		PF01979
(Amidohydro_1) 		4 LEU A 101
VAL A 126
LEU A 149
ARG A 172
 None
KCX  A 150 ( 4.3A)
KCX  A 150 ( 4.3A)
None
 0.97A 5x7zA-3sfwA:
undetectable		 5x7zA-3sfwA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sky COPPER-EXPORTING
P-TYPE ATPASE B

(Archaeoglobus
fulgidus) 		PF00702
(Hydrolase) 		4 LEU A 383
VAL A 386
LEU A 526
VAL A 581
 None
 0.86A 5x7zA-3skyA:
undetectable		 5x7zA-3skyA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t69 PUTATIVE
2-DEHYDRO-3-DEOXYGAL
ACTONOKINASE

(Sinorhizobium
meliloti) 		PF05035
(DGOK) 		4 LEU A  91
VAL A 163
LEU A 114
VAL A 156
 None
 0.88A 5x7zA-3t69A:
undetectable		 5x7zA-3t69A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3toj SET1/ASH2 HISTONE
METHYLTRANSFERASE
COMPLEX SUBUNIT ASH2

(Homo sapiens) 		PF00622
(SPRY) 		4 LEU A 298
ARG A 294
VAL A 307
LEU A 289
 None
 0.95A 5x7zA-3tojA:
undetectable		 5x7zA-3tojA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0h XYLOSE ISOMERASE
DOMAIN PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF01261
(AP_endonuc_2) 		4 LEU A  37
VAL A  32
ARG A  56
VAL A  30
 None
 0.97A 5x7zA-3u0hA:
undetectable		 5x7zA-3u0hA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vk5 MOEO5

(Streptomyces
viridosporus) 		PF01884
(PcrB) 		4 LEU A 219
VAL A 198
LEU A 200
VAL A 156
 None
 0.90A 5x7zA-3vk5A:
undetectable		 5x7zA-3vk5A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w3s TYPE-2 SERINE--TRNA
LIGASE

(Methanopyrus
kandleri) 		PF00587
(tRNA-synt_2b) 		4 LEU A 435
VAL A 433
LEU A 398
VAL A 450
 None
None
None
SSA  A2002 (-4.8A)
 0.75A 5x7zA-3w3sA:
0.9		 5x7zA-3w3sA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbk EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5B

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2) 		4 VAL A 127
LEU A  99
ARG A 119
VAL A 192
 None
 0.98A 5x7zA-3wbkA:
undetectable		 5x7zA-3wbkA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wib HALOALKANE
DEHALOGENASE

(Agrobacterium
fabrum) 		PF00561
(Abhydrolase_1) 		4 LEU A 224
ARG A 136
VAL A 134
ARG A 151
 None
 0.94A 5x7zA-3wibA:
undetectable		 5x7zA-3wibA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwz D-LACTATE
DEHYDROGENASE
(FERMENTATIVE)

(Pseudomonas
aeruginosa) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 LEU A  92
VAL A  72
LEU A  56
VAL A  48
 None
 0.94A 5x7zA-3wwzA:
undetectable		 5x7zA-3wwzA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zpx LIPASE

(Ustilago maydis) 		PF03583
(LIP) 		4 LEU A 295
VAL A 301
LEU A 305
VAL A 248
 None
 0.77A 5x7zA-3zpxA:
undetectable		 5x7zA-3zpxA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5w COMPLEMENT C5

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2) 		4 LEU A 602
VAL A 600
LEU A 571
VAL A 780
 None
 0.89A 5x7zA-4a5wA:
undetectable		 5x7zA-4a5wA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4arx PESTICIDAL CRYSTAL
PROTEIN CRY1AC

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 ARG A 368
VAL A 382
LEU A 366
ARG A 402
 None
 0.86A 5x7zA-4arxA:
1.9		 5x7zA-4arxA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4blq P4

(Pseudomonas
phage phi8) 		PF11602
(NTPase_P4) 		4 LEU A 173
VAL A 176
LEU A 180
VAL A 150
 None
 0.79A 5x7zA-4blqA:
undetectable		 5x7zA-4blqA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bwy P4

(Pseudomonas
phage phi8) 		PF11602
(NTPase_P4) 		4 LEU A 173
VAL A 176
LEU A 180
VAL A 150
 None
 0.94A 5x7zA-4bwyA:
undetectable		 5x7zA-4bwyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dgu PUTATIVE CELL
ADHESION PROTEIN

(Bacteroides
thetaiotaomicron) 		no annotation 4 LEU A 240
VAL A 209
LEU A 172
VAL A 152
 None
 0.93A 5x7zA-4dguA:
undetectable		 5x7zA-4dguA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4doi CHALCONE--FLAVONONE
ISOMERASE 1

(Arabidopsis
thaliana) 		PF02431
(Chalcone) 		4 LEU A  65
VAL A  63
LEU A 199
ARG A 213
 None
 0.96A 5x7zA-4doiA:
undetectable		 5x7zA-4doiA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ep5 CROSSOVER JUNCTION
ENDODEOXYRIBONUCLEAS
E RUVC

(Thermus
thermophilus) 		PF02075
(RuvC) 		4 LEU A  59
VAL A  55
LEU A  15
VAL A  91
 None
 0.76A 5x7zA-4ep5A:
undetectable		 5x7zA-4ep5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ex6 ALNB

(Streptomyces
sp. CM020) 		PF13419
(HAD_2) 		4 LEU A 106
VAL A  12
LEU A  14
VAL A 171
 None
 0.96A 5x7zA-4ex6A:
undetectable		 5x7zA-4ex6A:
26.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gnx PUTATIVE
UNCHARACTERIZED
PROTEIN
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Ustilago
maydis;
Ustilago maydis) 		PF01336
(tRNA_anti-codon)
PF01336
(tRNA_anti-codon)
PF08646
(Rep_fac-A_C)
PF16900
(REPA_OB_2) 		4 ARG B 163
VAL B 167
LEU B 164
ARG C 620
 None
 0.90A 5x7zA-4gnxB:
undetectable		 5x7zA-4gnxB:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4go6 HCF C-TERMINAL CHAIN
1

(Homo sapiens) 		no annotation 4 LEU B1908
VAL B1961
LEU B1966
VAL B1951
 None
 0.85A 5x7zA-4go6B:
undetectable		 5x7zA-4go6B:
26.41