SIMILAR PATTERNS OF AMINO ACIDS FOR 5X7P_B_ACRB1481_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dex RHAMNOGALACTURONAN
ACETYLESTERASE

(Aspergillus
aculeatus) 		PF13472
(Lipase_GDSL_2) 		4 SER A  98
ARG A  50
GLU A 105
TYR A 100
 None
 1.26A 5x7pB-1dexA:
undetectable		 5x7pB-1dexA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g38 MODIFICATION
METHYLASE TAQI

(Thermus
aquaticus) 		PF07669
(Eco57I)
PF12950
(TaqI_C) 		4 SER A 370
ARG A 406
GLU A 408
TYR A 409
 None
 1.50A 5x7pB-1g38A:
0.0		 5x7pB-1g38A:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j0n XANTHAN LYASE

(Bacillus sp.
GL1) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 TRP A 199
SER A 258
GLU A 310
TYR A 255
 None
CEG  A 780 ( 4.7A)
CEG  A 780 ( 4.3A)
CEG  A 780 (-4.4A)
 1.32A 5x7pB-1j0nA:
5.2		 5x7pB-1j0nA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcm PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
ALPHA

(Mus musculus) 		PF02121
(IP_trans) 		4 HIS A 127
ARG A   8
GLU A   6
TYR A 194
 None
 1.16A 5x7pB-1kcmA:
0.2		 5x7pB-1kcmA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lln ANTIVIRAL PROTEIN 3

(Phytolacca
americana) 		PF00161
(RIP) 		4 SER A 116
ARG A 127
GLU A 121
TYR A 117
 MLY  A 115 ( 4.2A)
None
None
None
 1.39A 5x7pB-1llnA:
0.0		 5x7pB-1llnA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mk2 SMAD 3

(Homo sapiens) 		PF03166
(MH2) 		4 SER A 235
HIS A 398
ARG A 372
GLU A 396
 None
None
ACY  A   2 (-4.5A)
None
 1.23A 5x7pB-1mk2A:
undetectable		 5x7pB-1mk2A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ms8 TRANS-SIALIDASE

(Trypanosoma
cruzi) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		4 SER A 343
ARG A  35
GLU A 357
TYR A 342
 None
DAN  A 700 (-3.0A)
None
DAN  A 700 (-3.5A)
 1.29A 5x7pB-1ms8A:
5.6		 5x7pB-1ms8A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mz5 SIALIDASE

(Trypanosoma
rangeli) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		4 SER A 344
ARG A  36
GLU A 358
TYR A 343
 None
 1.19A 5x7pB-1mz5A:
6.9		 5x7pB-1mz5A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nw1 CHOLINE KINASE (49.2
KD)

(Caenorhabditis
elegans) 		PF01633
(Choline_kinase) 		4 TRP A 201
HIS A 121
GLU A 303
TYR A 304
 None
 1.37A 5x7pB-1nw1A:
0.0		 5x7pB-1nw1A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ru4 PECTATE LYASE

(Dickeya
chrysanthemi) 		PF13229
(Beta_helix) 		4 TRP A 229
HIS A 172
ARG A 116
GLU A 148
 None
 1.27A 5x7pB-1ru4A:
undetectable		 5x7pB-1ru4A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE

(Bacillus
subtilis) 		PF03102
(NeuB)
PF08666
(SAF) 		4 SER A 130
ARG A 327
GLU A 132
TYR A 131
 None
 1.45A 5x7pB-1vliA:
undetectable		 5x7pB-1vliA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1l PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
BETA ISOFORM

(Rattus
norvegicus) 		PF02121
(IP_trans) 		4 HIS A 126
ARG A   8
GLU A   6
TYR A 193
 None
 1.13A 5x7pB-2a1lA:
2.0		 5x7pB-2a1lA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a8i THREONINE ASPARTASE
1

(Homo sapiens) 		PF01112
(Asparaginase_2) 		4 SER A 134
ARG A 172
GLU A 168
TYR A 171
 None
 1.01A 5x7pB-2a8iA:
undetectable		 5x7pB-2a8iA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fge ZINC METALLOPROTEASE
(INSULINASE FAMILY)

(Arabidopsis
thaliana) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		4 TRP A 738
SER A 742
ARG A 749
GLU A 746
 None
 1.36A 5x7pB-2fgeA:
undetectable		 5x7pB-2fgeA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lqt COILED-COIL-HELIX-CO
ILED-COIL-HELIX
DOMAIN-CONTAINING
PROTEIN 7

(Homo sapiens) 		no annotation 4 SER A  23
ARG A  43
GLU A  19
TYR A  40
 None
 1.46A 5x7pB-2lqtA:
undetectable		 5x7pB-2lqtA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpj KELCH-LIKE PROTEIN
12

(Homo sapiens) 		PF01344
(Kelch_1) 		4 SER A 464
ARG A 392
GLU A 417
TYR A 434
 None
None
ACT  A1569 (-3.8A)
None
 1.15A 5x7pB-2vpjA:
undetectable		 5x7pB-2vpjA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xt6 2-OXOGLUTARATE
DECARBOXYLASE

(Mycolicibacterium
smegmatis) 		PF00198
(2-oxoacid_dh)
PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF16870
(OxoGdeHyase_C) 		4 SER A 963
ARG A 897
GLU A 959
TYR A 962
 None
 1.44A 5x7pB-2xt6A:
undetectable		 5x7pB-2xt6A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ff6 ACETYL-COA
CARBOXYLASE 2

(Homo sapiens) 		PF01039
(Carboxyl_trans) 		4 SER A1919
ARG A2146
GLU A1923
TYR A1922
 None
 1.40A 5x7pB-3ff6A:
undetectable		 5x7pB-3ff6A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM

(Mus musculus) 		PF04916
(Phospholip_B) 		4 SER A  68
HIS A  85
ARG A  79
GLU A  81
 None
 1.26A 5x7pB-3fgtA:
undetectable		 5x7pB-3fgtA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxk SUGAR HYDROLASE

(Lactococcus
lactis) 		PF00326
(Peptidase_S9) 		4 TRP A 161
SER A 127
HIS A 231
GLU A  61
 None
 1.39A 5x7pB-3hxkA:
undetectable		 5x7pB-3hxkA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9t PUTATIVE PEPTIDASE

(Clostridium
acetobutylicum) 		PF09940
(DUF2172)
PF16221
(HTH_47)
PF16254
(DUF4910) 		4 HIS A 103
ARG A  78
GLU A 154
TYR A  76
 None
 1.29A 5x7pB-3k9tA:
undetectable		 5x7pB-3k9tA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oon OUTER MEMBRANE
PROTEIN (TPN50)

(Borreliella
burgdorferi) 		PF00691
(OmpA) 		4 SER A 335
HIS A 332
ARG A 340
GLU A 336
 None
 1.50A 5x7pB-3oonA:
2.1		 5x7pB-3oonA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppz SERINE/THREONINE-PRO
TEIN KINASE CTR1

(Arabidopsis
thaliana) 		PF07714
(Pkinase_Tyr) 		4 TRP A 717
SER A 679
ARG A 635
TYR A 634
 None
None
STU  A   1 (-2.9A)
None
 1.40A 5x7pB-3ppzA:
2.2		 5x7pB-3ppzA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhr MULTIFUNCTIONAL
2-OXOGLUTARATE
METABOLISM ENZYME

(Mycolicibacterium
smegmatis) 		PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF16870
(OxoGdeHyase_C) 		4 SER A 963
ARG A 897
GLU A 959
TYR A 962
 None
 1.46A 5x7pB-3zhrA:
undetectable		 5x7pB-3zhrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bbw SIALIDASE
(NEURAMINIDASE)

(Bacteroides
thetaiotaomicron) 		PF13088
(BNR_2)
PF14873
(BNR_assoc_N) 		4 SER A 511
ARG A 204
GLU A 526
TYR A 510
 None
 1.26A 5x7pB-4bbwA:
2.2		 5x7pB-4bbwA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fwv TTC1975 PEPTIDASE

(Meiothermus
taiwanensis) 		PF13654
(AAA_32) 		4 SER A 316
ARG A 276
GLU A 269
TYR A 271
 None
 1.47A 5x7pB-4fwvA:
undetectable		 5x7pB-4fwvA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l6y PROTEIN REGULATOR OF
CYTOKINESIS 1

(Homo sapiens) 		PF03999
(MAP65_ASE1) 		4 TRP A 436
HIS A 439
ARG A 392
GLU A 369
 None
 1.42A 5x7pB-4l6yA:
undetectable		 5x7pB-4l6yA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzm INOSITOL
HEXAKISPHOSPHATE AND
DIPHOSPHOINOSITOL-PE
NTAKISPHOSPHATE
KINASE 2

(Homo sapiens) 		no annotation 4 SER A 331
HIS A 258
ARG A 281
GLU A 260
 None
 1.48A 5x7pB-4nzmA:
undetectable		 5x7pB-4nzmA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p2b GLUTAMINE
AMINOACYL-TRNA
SYNTHETASE

(Toxoplasma
gondii) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		4 SER A 114
HIS A 212
GLU A  88
TYR A 112
 None
 1.24A 5x7pB-4p2bA:
undetectable		 5x7pB-4p2bA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4sli INTRAMOLECULAR
TRANS-SIALIDASE

(Macrobdella
decora) 		PF02973
(Sialidase)
PF13088
(BNR_2) 		4 SER A 714
ARG A 293
GLU A 729
TYR A 713
 None
CNP  A 760 (-3.0A)
None
CNP  A 760 (-4.0A)
 1.18A 5x7pB-4sliA:
3.1		 5x7pB-4sliA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tkc MANNOSE RECOGNIZING
LECTIN

(Marasmius
oreades) 		no annotation 4 HIS A   4
ARG A  32
GLU A  30
TYR A   2
 None
 1.08A 5x7pB-4tkcA:
undetectable		 5x7pB-4tkcA:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x28 ACYL-COA
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 SER A   4
ARG A  13
GLU A  10
TYR A   5
 None
 1.34A 5x7pB-4x28A:
undetectable		 5x7pB-4x28A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x6k ANHYDROSIALIDASE

([Ruminococcus]
gnavus) 		PF13088
(BNR_2) 		4 SER A 678
ARG A 257
GLU A 693
TYR A 677
 None
3XR  A 802 (-3.0A)
None
3XR  A 802 (-4.2A)
 1.21A 5x7pB-4x6kA:
undetectable		 5x7pB-4x6kA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhb SIALIDASE B

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		4 SER A 654
ARG A 245
GLU A 669
TYR A 653
 None
NHE  A 702 (-2.7A)
None
NHE  A 702 (-4.8A)
 1.21A 5x7pB-4xhbA:
4.4		 5x7pB-4xhbA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yw5 NEURAMINIDASE C

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		4 SER A 696
ARG A 290
GLU A 711
TYR A 695
 None
G39  A 801 (-2.6A)
None
G39  A 801 (-4.4A)
 1.20A 5x7pB-4yw5A:
4.2		 5x7pB-4yw5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b47 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01558
(POR)
PF01855
(POR_N)
PF17147
(PFOR_II) 		4 SER A 415
HIS A 381
ARG A  38
TYR A 414
 None
 1.36A 5x7pB-5b47A:
undetectable		 5x7pB-5b47A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b47 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01558
(POR)
PF01855
(POR_N)
PF17147
(PFOR_II) 		4 TRP A 329
HIS A 470
ARG A 444
TYR A 465
 None
 1.22A 5x7pB-5b47A:
undetectable		 5x7pB-5b47A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01558
(POR)
PF01855
(POR_N) 		4 TRP A 329
HIS A 470
ARG A 444
TYR A 465
 None
 1.25A 5x7pB-5b48A:
undetectable		 5x7pB-5b48A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cgl ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE NMFIC

(Neisseria
meningitidis) 		PF02661
(Fic) 		4 TRP A 135
SER A 182
GLU A 186
TYR A 185
 None
None
PEG  A 201 (-3.9A)
None
 1.46A 5x7pB-5cglA:
undetectable		 5x7pB-5cglA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5en4 17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14

(Homo sapiens) 		PF13561
(adh_short_C2) 		4 SER A 173
ARG A 130
GLU A 172
TYR A 175
 None
 1.28A 5x7pB-5en4A:
undetectable		 5x7pB-5en4A:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo sapiens) 		PF03071
(GNT-I)
PF15711
(ILEI) 		4 TRP A 206
SER A 182
ARG A 129
TYR A 152
 None
 1.28A 5x7pB-5gggA:
2.6		 5x7pB-5gggA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9d FARNESYL
PYROPHOSPHATE
SYNTHETASE

(Staphylococcus
aureus) 		PF00348
(polyprenyl_synt) 		4 SER A  61
ARG A  16
GLU A  62
TYR A  65
 None
 1.38A 5x7pB-5h9dA:
undetectable		 5x7pB-5h9dA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mm7 -

(-) 		no annotation 4 SER K 322
ARG K 242
GLU K 235
TYR K 237
 None
 1.11A 5x7pB-5mm7K:
undetectable		 5x7pB-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE

(Mus musculus) 		PF06090
(Ins_P5_2-kin) 		4 SER A 454
HIS A 152
GLU A 334
TYR A 450
 None
 1.31A 5x7pB-5mwlA:
undetectable		 5x7pB-5mwlA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ohs -

(-) 		no annotation 4 TRP A 452
HIS A 520
GLU A 270
TYR A 315
 NSQ  A 709 (-4.9A)
NSQ  A 709 (-3.9A)
NSQ  A 709 (-2.6A)
NSQ  A 709 ( 4.8A)
 1.31A 5x7pB-5ohsA:
22.1		 5x7pB-5ohsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uqj U6 SNRNA
PHOSPHODIESTERASE

(Saccharomyces
cerevisiae) 		PF09749
(HVSL) 		4 SER A 284
HIS A 283
ARG A 286
TYR A 277
 None
None
ACT  A 307 (-3.5A)
None
 1.34A 5x7pB-5uqjA:
undetectable		 5x7pB-5uqjA:
10.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5x7s GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE

(Paenibacillus
sp. 598K) 		PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF16990
(CBM_35)
PF17137
(DUF5110) 		6 TRP A1148
SER A1189
HIS A1191
ARG A1220
GLU A1222
TYR A1261
 None
 0.30A 5x7pB-5x7sA:
58.3		 5x7pB-5x7sA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6am0 KLLA0F23980P

(Kluyveromyces
lactis) 		no annotation 4 TRP A  49
HIS A 194
ARG A 147
GLU A 151
 6VQ  A 302 (-3.4A)
6VQ  A 302 (-4.0A)
None
None
 1.38A 5x7pB-6am0A:
undetectable		 5x7pB-6am0A:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli) 		no annotation 4 TRP A  67
SER A  63
HIS A  64
ARG A  98
 None
 1.15A 5x7pB-6bogA:
undetectable		 5x7pB-6bogA:
4.75