SIMILAR PATTERNS OF AMINO ACIDS FOR 5X7P_A_ACRA1481

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g38 MODIFICATION
METHYLASE TAQI

(Thermus
aquaticus) 		PF07669
(Eco57I)
PF12950
(TaqI_C) 		4 SER A 370
ARG A 406
GLU A 408
TYR A 409
 None
 1.49A 5x7pA-1g38A:
0.0		 5x7pA-1g38A:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j0n XANTHAN LYASE

(Bacillus sp.
GL1) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 TRP A 199
SER A 258
GLU A 310
TYR A 255
 None
CEG  A 780 ( 4.7A)
CEG  A 780 ( 4.3A)
CEG  A 780 (-4.4A)
 1.34A 5x7pA-1j0nA:
5.3		 5x7pA-1j0nA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcm PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
ALPHA

(Mus musculus) 		PF02121
(IP_trans) 		4 HIS A 127
ARG A   8
GLU A   6
TYR A 194
 None
 1.10A 5x7pA-1kcmA:
1.2		 5x7pA-1kcmA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lln ANTIVIRAL PROTEIN 3

(Phytolacca
americana) 		PF00161
(RIP) 		4 SER A 116
ARG A 127
GLU A 121
TYR A 117
 MLY  A 115 ( 4.2A)
None
None
None
 1.40A 5x7pA-1llnA:
0.0		 5x7pA-1llnA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ms8 TRANS-SIALIDASE

(Trypanosoma
cruzi) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		4 SER A 343
ARG A  35
GLU A 357
TYR A 342
 None
DAN  A 700 (-3.0A)
None
DAN  A 700 (-3.5A)
 1.23A 5x7pA-1ms8A:
7.0		 5x7pA-1ms8A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mz5 SIALIDASE

(Trypanosoma
rangeli) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		4 SER A 344
ARG A  36
GLU A 358
TYR A 343
 None
 1.14A 5x7pA-1mz5A:
6.9		 5x7pA-1mz5A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nmb N9 NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 SER N 407
ARG N 118
GLU N 425
TYR N 406
 None
 1.25A 5x7pA-1nmbN:
undetectable		 5x7pA-1nmbN:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nw1 CHOLINE KINASE (49.2
KD)

(Caenorhabditis
elegans) 		PF01633
(Choline_kinase) 		4 TRP A 201
HIS A 121
GLU A 303
TYR A 304
 None
 1.35A 5x7pA-1nw1A:
0.0		 5x7pA-1nw1A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o7f CAMP-DEPENDENT RAP1
GUANINE-NUCLEOTIDE
EXCHANGE FACTOR

(Mus musculus) 		PF00027
(cNMP_binding)
PF00610
(DEP) 		4 HIS A 359
ARG A 429
GLU A 357
TYR A 377
 None
 1.43A 5x7pA-1o7fA:
undetectable		 5x7pA-1o7fA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r9j TRANSKETOLASE

(Leishmania
mexicana) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 HIS A 619
ARG A 490
GLU A 605
TYR A 607
 None
 1.49A 5x7pA-1r9jA:
undetectable		 5x7pA-1r9jA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ru4 PECTATE LYASE

(Dickeya
chrysanthemi) 		PF13229
(Beta_helix) 		4 TRP A 229
HIS A 172
ARG A 116
GLU A 148
 None
 1.29A 5x7pA-1ru4A:
undetectable		 5x7pA-1ru4A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xog NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 SER A 407
ARG A 119
GLU A 427
TYR A 406
 None
ABW  A1000 (-3.2A)
None
ABW  A1000 (-4.9A)
 1.10A 5x7pA-1xogA:
undetectable		 5x7pA-1xogA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4

(Viscum album) 		PF00161
(RIP) 		4 SER A 109
ARG A 120
GLU A 114
TYR A 110
 P6C  A1001 (-3.5A)
None
None
None
 1.48A 5x7pA-1yf8A:
undetectable		 5x7pA-1yf8A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1l PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
BETA ISOFORM

(Rattus
norvegicus) 		PF02121
(IP_trans) 		4 HIS A 126
ARG A   8
GLU A   6
TYR A 193
 None
 1.06A 5x7pA-2a1lA:
1.8		 5x7pA-2a1lA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a8i THREONINE ASPARTASE
1

(Homo sapiens) 		PF01112
(Asparaginase_2) 		4 SER A 134
ARG A 172
GLU A 168
TYR A 171
 None
 0.98A 5x7pA-2a8iA:
undetectable		 5x7pA-2a8iA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lqt COILED-COIL-HELIX-CO
ILED-COIL-HELIX
DOMAIN-CONTAINING
PROTEIN 7

(Homo sapiens) 		no annotation 4 SER A  23
ARG A  43
GLU A  19
TYR A  40
 None
 1.46A 5x7pA-2lqtA:
undetectable		 5x7pA-2lqtA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpj KELCH-LIKE PROTEIN
12

(Homo sapiens) 		PF01344
(Kelch_1) 		4 SER A 464
ARG A 392
GLU A 417
TYR A 434
 None
None
ACT  A1569 (-3.8A)
None
 1.14A 5x7pA-2vpjA:
undetectable		 5x7pA-2vpjA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xt6 2-OXOGLUTARATE
DECARBOXYLASE

(Mycolicibacterium
smegmatis) 		PF00198
(2-oxoacid_dh)
PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF16870
(OxoGdeHyase_C) 		4 SER A 963
ARG A 897
GLU A 959
TYR A 962
 None
 1.47A 5x7pA-2xt6A:
undetectable		 5x7pA-2xt6A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgt PUTATIVE
PHOSPHOLIPASE B-LIKE
2 28 KDA FORM

(Mus musculus) 		PF04916
(Phospholip_B) 		4 SER A  68
HIS A  85
ARG A  79
GLU A  81
 None
 1.33A 5x7pA-3fgtA:
undetectable		 5x7pA-3fgtA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxk SUGAR HYDROLASE

(Lactococcus
lactis) 		PF00326
(Peptidase_S9) 		4 TRP A 161
SER A 127
HIS A 231
GLU A  61
 None
 1.37A 5x7pA-3hxkA:
undetectable		 5x7pA-3hxkA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9t PUTATIVE PEPTIDASE

(Clostridium
acetobutylicum) 		PF09940
(DUF2172)
PF16221
(HTH_47)
PF16254
(DUF4910) 		4 HIS A 103
ARG A  78
GLU A 154
TYR A  76
 None
 1.29A 5x7pA-3k9tA:
undetectable		 5x7pA-3k9tA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppz SERINE/THREONINE-PRO
TEIN KINASE CTR1

(Arabidopsis
thaliana) 		PF07714
(Pkinase_Tyr) 		4 TRP A 717
SER A 679
ARG A 635
TYR A 634
 None
None
STU  A   1 (-2.9A)
None
 1.38A 5x7pA-3ppzA:
undetectable		 5x7pA-3ppzA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rmh YEAST CDC13 OB4

([Candida]
glabrata) 		no annotation 4 SER A 722
ARG A 652
GLU A 650
TYR A 675
 None
 1.28A 5x7pA-3rmhA:
undetectable		 5x7pA-3rmhA:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sil SIALIDASE

(Salmonella
enterica) 		PF13859
(BNR_3) 		4 SER A 343
ARG A  37
GLU A 361
TYR A 342
 None
PO4  A 499 (-2.7A)
None
PO4  A 499 (-4.6A)
 1.19A 5x7pA-3silA:
undetectable		 5x7pA-3silA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhr MULTIFUNCTIONAL
2-OXOGLUTARATE
METABOLISM ENZYME

(Mycolicibacterium
smegmatis) 		PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF16870
(OxoGdeHyase_C) 		4 SER A 963
ARG A 897
GLU A 959
TYR A 962
 None
 1.49A 5x7pA-3zhrA:
undetectable		 5x7pA-3zhrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l6y PROTEIN REGULATOR OF
CYTOKINESIS 1

(Homo sapiens) 		PF03999
(MAP65_ASE1) 		4 TRP A 436
HIS A 439
ARG A 392
GLU A 369
 None
 1.41A 5x7pA-4l6yA:
undetectable		 5x7pA-4l6yA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l9a PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1393C

(Streptococcus
mutans) 		no annotation 4 SER A 233
ARG A 226
GLU A 229
TYR A 230
 None
 1.44A 5x7pA-4l9aA:
undetectable		 5x7pA-4l9aA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p2b GLUTAMINE
AMINOACYL-TRNA
SYNTHETASE

(Toxoplasma
gondii) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		4 SER A 114
HIS A 212
GLU A  88
TYR A 112
 None
 1.23A 5x7pA-4p2bA:
2.1		 5x7pA-4p2bA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4sli INTRAMOLECULAR
TRANS-SIALIDASE

(Macrobdella
decora) 		PF02973
(Sialidase)
PF13088
(BNR_2) 		4 SER A 714
ARG A 293
GLU A 729
TYR A 713
 None
CNP  A 760 (-3.0A)
None
CNP  A 760 (-4.0A)
 1.14A 5x7pA-4sliA:
4.1		 5x7pA-4sliA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tkc MANNOSE RECOGNIZING
LECTIN

(Marasmius
oreades) 		no annotation 4 HIS A   4
ARG A  32
GLU A  30
TYR A   2
 None
 1.07A 5x7pA-4tkcA:
undetectable		 5x7pA-4tkcA:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x28 ACYL-COA
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 SER A   4
ARG A  13
GLU A  10
TYR A   5
 None
 1.32A 5x7pA-4x28A:
undetectable		 5x7pA-4x28A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x6k ANHYDROSIALIDASE

([Ruminococcus]
gnavus) 		PF13088
(BNR_2) 		4 SER A 678
ARG A 257
GLU A 693
TYR A 677
 None
3XR  A 802 (-3.0A)
None
3XR  A 802 (-4.2A)
 1.16A 5x7pA-4x6kA:
undetectable		 5x7pA-4x6kA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhb SIALIDASE B

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		4 SER A 654
ARG A 245
GLU A 669
TYR A 653
 None
NHE  A 702 (-2.7A)
None
NHE  A 702 (-4.8A)
 1.16A 5x7pA-4xhbA:
undetectable		 5x7pA-4xhbA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yw5 NEURAMINIDASE C

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		4 SER A 696
ARG A 290
GLU A 711
TYR A 695
 None
G39  A 801 (-2.6A)
None
G39  A 801 (-4.4A)
 1.15A 5x7pA-4yw5A:
4.1		 5x7pA-4yw5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b47 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01558
(POR)
PF01855
(POR_N)
PF17147
(PFOR_II) 		4 SER A 415
HIS A 381
ARG A  38
TYR A 414
 None
 1.37A 5x7pA-5b47A:
undetectable		 5x7pA-5b47A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b47 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01558
(POR)
PF01855
(POR_N)
PF17147
(PFOR_II) 		4 TRP A 329
HIS A 470
ARG A 444
TYR A 465
 None
 1.18A 5x7pA-5b47A:
undetectable		 5x7pA-5b47A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b48 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
ALPHA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01558
(POR)
PF01855
(POR_N) 		4 TRP A 329
HIS A 470
ARG A 444
TYR A 465
 None
 1.21A 5x7pA-5b48A:
undetectable		 5x7pA-5b48A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cgl ADENOSINE
MONOPHOSPHATE-PROTEI
N TRANSFERASE NMFIC

(Neisseria
meningitidis) 		PF02661
(Fic) 		4 TRP A 135
SER A 182
GLU A 186
TYR A 185
 None
None
PEG  A 201 (-3.9A)
None
 1.46A 5x7pA-5cglA:
undetectable		 5x7pA-5cglA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ggg PROTEIN
O-LINKED-MANNOSE
BETA-1,2-N-ACETYLGLU
COSAMINYLTRANSFERASE
1

(Homo sapiens) 		PF03071
(GNT-I)
PF15711
(ILEI) 		4 TRP A 206
SER A 182
ARG A 129
TYR A 152
 None
 1.26A 5x7pA-5gggA:
undetectable		 5x7pA-5gggA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9d FARNESYL
PYROPHOSPHATE
SYNTHETASE

(Staphylococcus
aureus) 		PF00348
(polyprenyl_synt) 		4 SER A  61
ARG A  16
GLU A  62
TYR A  65
 None
 1.39A 5x7pA-5h9dA:
undetectable		 5x7pA-5h9dA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE

(Mus musculus) 		PF06090
(Ins_P5_2-kin) 		4 SER A 454
HIS A 152
GLU A 334
TYR A 450
 None
 1.29A 5x7pA-5mwlA:
undetectable		 5x7pA-5mwlA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ohs -

(-) 		no annotation 4 TRP A 452
HIS A 520
GLU A 270
TYR A 315
 NSQ  A 709 (-4.9A)
NSQ  A 709 (-3.9A)
NSQ  A 709 (-2.6A)
NSQ  A 709 ( 4.8A)
 1.35A 5x7pA-5ohsA:
22.2		 5x7pA-5ohsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uqj U6 SNRNA
PHOSPHODIESTERASE

(Saccharomyces
cerevisiae) 		PF09749
(HVSL) 		4 SER A 284
HIS A 283
ARG A 286
TYR A 277
 None
None
ACT  A 307 (-3.5A)
None
 1.30A 5x7pA-5uqjA:
undetectable		 5x7pA-5uqjA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vh6 ELONGATION FACTOR G

(Bacillus
subtilis) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		4 SER A 338
ARG A 348
GLU A 391
TYR A 339
 None
 1.37A 5x7pA-5vh6A:
undetectable		 5x7pA-5vh6A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w99 PBTD

(Planobispora
rosea) 		no annotation 4 HIS A 311
ARG A 202
GLU A 198
TYR A 201
 None
 1.06A 5x7pA-5w99A:
undetectable		 5x7pA-5w99A:
5.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5x7s GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE

(Paenibacillus
sp. 598K) 		PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF16990
(CBM_35)
PF17137
(DUF5110) 		6 TRP A1148
SER A1189
HIS A1191
ARG A1220
GLU A1222
TYR A1261
 None
 0.28A 5x7pA-5x7sA:
59.0		 5x7pA-5x7sA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6am0 KLLA0F23980P

(Kluyveromyces
lactis) 		no annotation 4 TRP A  49
HIS A 194
ARG A 147
GLU A 151
 6VQ  A 302 (-3.4A)
6VQ  A 302 (-4.0A)
None
None
 1.37A 5x7pA-6am0A:
undetectable		 5x7pA-6am0A:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli) 		no annotation 4 TRP A  67
SER A  63
HIS A  64
ARG A  98
 None
 1.17A 5x7pA-6bogA:
undetectable		 5x7pA-6bogA:
4.75