SIMILAR PATTERNS OF AMINO ACIDS FOR 5X1F_W_CHDW101

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dlc DELTA-ENDOTOXIN
CRYIIIA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 TYR A 268
ARG A 269
MET A 272
THR A 273
 None
 1.22A 5x1fW-1dlcA:
0.0		 5x1fW-1dlcA:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ep2 DIHYDROOROTATE
DEHYDROGENASE B
(PYRK SUBUNIT)

(Lactococcus
lactis) 		PF00175
(NAD_binding_1)
PF10418
(DHODB_Fe-S_bind) 		4 TYR B  71
MET B  23
THR B  68
LEU B  25
 None
 1.34A 5x1fW-1ep2B:
0.0		 5x1fW-1ep2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flo FLP RECOMBINASE

(Saccharomyces
cerevisiae) 		PF03930
(Flp_N)
PF05202
(Flp_C) 		4 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.96A 5x1fW-1floA:
0.0		 5x1fW-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iw8 ACID PHOSPHATASE

(Shimwellia
blattae) 		PF01569
(PAP2) 		4 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.35A 5x1fW-1iw8A:
0.0		 5x1fW-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1khc DNA CYTOSINE-5
METHYLTRANSFERASE
3B2

(Mus musculus) 		PF00855
(PWWP) 		4 TYR A 305
ARG A 306
MET A 309
LEU A 313
 None
 0.98A 5x1fW-1khcA:
undetectable		 5x1fW-1khcA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lrw METHANOL
DEHYDROGENASE
SUBUNIT 1

(Paracoccus
denitrificans) 		PF01011
(PQQ)
PF13360
(PQQ_2) 		4 ARG A 383
MET A 416
THR A 437
LEU A 436
 None
 0.87A 5x1fW-1lrwA:
0.0		 5x1fW-1lrwA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lrw METHANOL
DEHYDROGENASE
SUBUNIT 1

(Paracoccus
denitrificans) 		PF01011
(PQQ)
PF13360
(PQQ_2) 		4 ARG A 446
MET A 438
THR A 437
LEU A 436
 None
 1.27A 5x1fW-1lrwA:
0.0		 5x1fW-1lrwA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3i GLUTATHIONE
S-TRANSFERASE 28 KDA

(Schistosoma
mansoni) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A  92
MET A  85
THR A 157
LEU A 158
 None
 1.18A 5x1fW-1u3iA:
0.0		 5x1fW-1u3iA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1usy ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT

(Thermotoga
maritima) 		PF13393
(tRNA-synt_His) 		4 ARG C 186
MET C 195
THR C 194
LEU C 192
 None
 1.39A 5x1fW-1usyC:
0.0		 5x1fW-1usyC:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcz RNASE NGR3

(Nicotiana
glutinosa) 		PF00445
(Ribonuclease_T2) 		4 ARG A 116
MET A  72
THR A  71
LEU A  68
 None
 1.08A 5x1fW-1vczA:
0.0		 5x1fW-1vczA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yx0 HYPOTHETICAL PROTEIN
YSNE

(Bacillus
subtilis) 		PF00583
(Acetyltransf_1) 		4 TYR A 131
MET A 147
THR A 148
LEU A 109
 None
 1.28A 5x1fW-1yx0A:
undetectable		 5x1fW-1yx0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 TYR A1179
ARG A1205
THR A1207
LEU A1210
 None
 1.15A 5x1fW-2b39A:
undetectable		 5x1fW-2b39A:
3.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c6w PENICILLIN-BINDING
PROTEIN 1A

(Streptococcus
pneumoniae) 		PF00905
(Transpeptidase) 		4 TYR B 618
ARG B 619
MET B 622
THR B 623
 None
 0.89A 5x1fW-2c6wB:
undetectable		 5x1fW-2c6wB:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c9k PESTICIDAL CRYSTAL
PROTEIN CRY4AA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 TYR A 295
ARG A 296
MET A 299
THR A 300
 None
 1.16A 5x1fW-2c9kA:
undetectable		 5x1fW-2c9kA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cai GLUTATHIONE
S-TRANSFERASE 28 KDA

(Schistosoma
haematobium) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A  92
MET A  85
THR A 157
LEU A 158
 PG4  A1218 (-3.6A)
None
None
None
 1.14A 5x1fW-2caiA:
undetectable		 5x1fW-2caiA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE

(Porphyromonas
gingivalis) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 TYR A 604
MET A 608
THR A 609
LEU A 612
 None
 1.07A 5x1fW-2d5lA:
undetectable		 5x1fW-2d5lA:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fe8 REPLICASE
POLYPROTEIN 1AB

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF08715
(Viral_protease) 		4 ARG A 167
MET A 170
THR A 171
LEU A 174
 None
 0.59A 5x1fW-2fe8A:
undetectable		 5x1fW-2fe8A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fqz R.ECL18KI

(Enterobacter
cloacae) 		PF09019
(EcoRII-C) 		4 TYR A 205
MET A 177
THR A 176
LEU A 258
 None
 1.36A 5x1fW-2fqzA:
undetectable		 5x1fW-2fqzA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jii SERINE/THREONINE-PRO
TEIN KINASE VRK3
MOLECULE: VACCINIA
RELATED KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 141
MET A 145
THR A 147
LEU A 149
 None
 1.29A 5x1fW-2jiiA:
undetectable		 5x1fW-2jiiA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ocd L-ASPARAGINASE I

(Vibrio cholerae) 		PF00710
(Asparaginase) 		4 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.12A 5x1fW-2ocdA:
undetectable		 5x1fW-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ola O-SUCCINYLBENZOIC
ACID SYNTHETASE

(Staphylococcus
aureus) 		PF13378
(MR_MLE_C) 		4 TYR A 280
MET A 284
THR A 282
LEU A 285
 None
 1.30A 5x1fW-2olaA:
undetectable		 5x1fW-2olaA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qlv PROTEIN SIP2
NUCLEAR PROTEIN SNF4

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF04739
(AMPKBI)
PF16561
(AMPK1_CBM)
PF00571
(CBS) 		4 TYR B 242
ARG B 214
THR B 233
LEU C  35
 None
 1.38A 5x1fW-2qlvB:
undetectable		 5x1fW-2qlvB:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vmf BETA-MANNOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2) 		4 ARG A 216
MET A  34
THR A 214
LEU A  36
 None
 1.25A 5x1fW-2vmfA:
undetectable		 5x1fW-2vmfA:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vq5 S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum) 		PF00407
(Bet_v_1) 		4 TYR A 108
MET A  97
THR A  98
LEU A  83
 None
HBA  A1203 (-3.4A)
None
None
 1.29A 5x1fW-2vq5A:
undetectable		 5x1fW-2vq5A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN

(Bordetella
bronchiseptica) 		PF04183
(IucA_IucC)
PF06276
(FhuF) 		4 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.35A 5x1fW-2x0qA:
undetectable		 5x1fW-2x0qA:
11.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos taurus) 		PF02238
(COX7a) 		5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
 None
 0.48A 5x1fW-2y69J:
7.8		 5x1fW-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yv3 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Thermus
thermophilus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 TYR A 276
MET A 278
THR A 281
LEU A 280
 None
 1.21A 5x1fW-2yv3A:
undetectable		 5x1fW-2yv3A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ziu MUS81 PROTEIN

(Danio rerio) 		PF02732
(ERCC4) 		4 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.53A 5x1fW-2ziuA:
undetectable		 5x1fW-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a75 GAMMA-GLUTAMYLTRANSP
EPTIDASE LARGE CHAIN

(Bacillus
subtilis) 		PF01019
(G_glu_transpept) 		4 TYR A 332
MET A 328
THR A 327
LEU A 324
 None
 1.03A 5x1fW-3a75A:
undetectable		 5x1fW-3a75A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b7y E3 UBIQUITIN-PROTEIN
LIGASE NEDD4

(Homo sapiens) 		PF00168
(C2) 		4 ARG A 124
MET A 248
THR A 249
LEU A 213
 None
 1.37A 5x1fW-3b7yA:
undetectable		 5x1fW-3b7yA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bh1 UPF0371 PROTEIN
DIP2346

(Corynebacterium
diphtheriae) 		PF08903
(DUF1846) 		4 TYR A  12
ARG A   9
MET A  60
LEU A  61
 None
 1.32A 5x1fW-3bh1A:
undetectable		 5x1fW-3bh1A:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bkx SAM-DEPENDENT
METHYLTRANSFERASE

(Lactobacillus
paracasei) 		PF13649
(Methyltransf_25) 		4 TYR A 133
ARG A 193
THR A 194
LEU A 195
 None
 1.19A 5x1fW-3bkxA:
undetectable		 5x1fW-3bkxA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmm UBIQUITIN-ACTIVATING
ENZYME E1 1

(Saccharomyces
cerevisiae) 		PF00899
(ThiF)
PF09358
(E1_UFD)
PF10585
(UBA_e1_thiolCys)
PF16190
(E1_FCCH)
PF16191
(E1_4HB) 		4 TYR A 959
MET A1001
THR A1000
LEU A1024
 None
 1.12A 5x1fW-3cmmA:
undetectable		 5x1fW-3cmmA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebv CHINITASE A

(Streptomyces
coelicolor) 		PF00704
(Glyco_hydro_18) 		4 TYR A 162
MET A 148
THR A 147
LEU A 146
 None
 1.38A 5x1fW-3ebvA:
undetectable		 5x1fW-3ebvA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gf6 UNCHARACTERIZED
BACTERIAL
LIPOPROTEIN

(Bacteroides
thetaiotaomicron) 		PF12956
(DUF3845) 		4 TYR A  68
MET A 105
THR A 104
LEU A 103
 None
 1.33A 5x1fW-3gf6A:
undetectable		 5x1fW-3gf6A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwy PUTATIVE CTP
PYROPHOSPHOHYDROLASE

(Bacteroides
fragilis) 		PF00293
(NUDIX) 		4 TYR A  61
ARG A  94
MET A  59
LEU A  97
 None
 1.38A 5x1fW-3gwyA:
undetectable		 5x1fW-3gwyA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04

(Sarcoptes
scabiei) 		PF00089
(Trypsin) 		4 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.25A 5x1fW-3h7oA:
undetectable		 5x1fW-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE

(Bacteroides
thetaiotaomicron) 		PF00809
(Pterin_bind) 		4 ARG A 407
MET A 410
THR A 411
LEU A 414
 None
 0.86A 5x1fW-3k13A:
undetectable		 5x1fW-3k13A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntk MATERNAL PROTEIN
TUDOR

(Drosophila
melanogaster) 		PF00567
(TUDOR) 		4 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.20A 5x1fW-3ntkA:
undetectable		 5x1fW-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nu8 AMINOTRANSFERASE
WBPE

(Pseudomonas
aeruginosa) 		PF01041
(DegT_DnrJ_EryC1) 		4 ARG A 287
MET A 337
THR A 285
LEU A 339
 None
 1.26A 5x1fW-3nu8A:
undetectable		 5x1fW-3nu8A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8c NCK-ASSOCIATED
PROTEIN 1

(Homo sapiens) 		PF09735
(Nckap1) 		4 ARG B 149
MET B 144
THR B 142
LEU B 143
 None
 1.33A 5x1fW-3p8cB:
undetectable		 5x1fW-3p8cB:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psf TRANSCRIPTION
ELONGATION FACTOR
SPT6

(Saccharomyces
cerevisiae) 		PF14635
(HHH_7)
PF14639
(YqgF)
PF14641
(HTH_44)
PF14878
(DLD) 		4 ARG A 957
MET A 310
THR A 311
LEU A 305
 None
 1.37A 5x1fW-3psfA:
undetectable		 5x1fW-3psfA:
4.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6v BETA-LACTAMASE

(Serratia
fonticola) 		PF00753
(Lactamase_B) 		4 TYR A 191
MET A 141
THR A 142
LEU A 145
 None
 0.95A 5x1fW-3q6vA:
undetectable		 5x1fW-3q6vA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli) 		PF06977
(SdiA-regulated) 		4 ARG A 130
MET A 122
THR A 108
LEU A 109
 None
 1.23A 5x1fW-3qqzA:
undetectable		 5x1fW-3qqzA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3se7 VANA

(-) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 TYR A 315
MET A 319
THR A 320
LEU A 324
 None
 0.93A 5x1fW-3se7A:
undetectable		 5x1fW-3se7A:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tat TYROSINE
AMINOTRANSFERASE

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 ARG A 374
MET A  21
THR A  19
LEU A  18
 None
 1.35A 5x1fW-3tatA:
undetectable		 5x1fW-3tatA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr1 PEPTIDE CHAIN
RELEASE FACTOR 3

(Desulfovibrio
vulgaris) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF16658
(RF3_C) 		4 TYR A 244
MET A 137
THR A 138
LEU A 109
 None
 1.32A 5x1fW-3vr1A:
undetectable		 5x1fW-3vr1A:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vts CYTOTOXIN 1

(Hemachatus
haemachatus) 		PF00087
(Toxin_TOLIP) 		4 TYR A  23
ARG A  37
MET A  25
THR A  26
 None
 1.01A 5x1fW-3vtsA:
undetectable		 5x1fW-3vtsA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wel ALPHA-GLUCOSIDASE

(Beta vulgaris) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16863
(NtCtMGAM_N) 		4 TYR A 620
MET A 583
THR A 582
LEU A 584
 None
 1.24A 5x1fW-3welA:
undetectable		 5x1fW-3welA:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wso F-BOX ONLY PROTEIN
44

(Homo sapiens) 		PF04300
(FBA)
PF12937
(F-box-like) 		4 TYR A 216
MET A 151
THR A 153
LEU A 150
 None
 1.24A 5x1fW-3wsoA:
undetectable		 5x1fW-3wsoA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhe NONSENSE-MEDIATED
MRNA DECAY PROTEIN
PROTEIN SMG-7

(Caenorhabditis
elegans;
Caenorhabditis
elegans) 		no annotation
PF10373
(EST1_DNA_bind) 		4 TYR A 132
ARG A 135
THR B 107
LEU B 106
 None
 1.34A 5x1fW-3zheA:
undetectable		 5x1fW-3zheA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zxs CRYPTOCHROME B

(Rhodobacter
sphaeroides) 		PF04244
(DPRP) 		4 TYR A 439
ARG A 343
MET A 344
LEU A 347
 None
None
SF4  A1510 (-4.5A)
None
 1.25A 5x1fW-3zxsA:
undetectable		 5x1fW-3zxsA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4apf CULLIN 3

(Homo sapiens) 		PF00888
(Cullin) 		4 TYR B  58
ARG B  59
THR B  63
LEU B  66
 None
 1.14A 5x1fW-4apfB:
undetectable		 5x1fW-4apfB:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bht NADP-SPECIFIC
GLUTAMATE
DEHYDROGENASE

(Escherichia
coli) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ARG A 156
MET A 151
THR A 152
LEU A 150
 GOL  A1450 (-3.6A)
None
None
None
 1.35A 5x1fW-4bhtA:
undetectable		 5x1fW-4bhtA:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7x MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 15

([Candida]
glabrata) 		PF16987
(KIX_2) 		4 ARG A  76
MET A  24
THR A  21
LEU A  20
 None
 1.35A 5x1fW-4d7xA:
undetectable		 5x1fW-4d7xA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4es7 PROTEIN AMBP

(Homo sapiens) 		PF00061
(Lipocalin) 		4 TYR A  72
MET A  55
THR A  56
LEU A  42
 None
 1.40A 5x1fW-4es7A:
undetectable		 5x1fW-4es7A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f62 GERANYLTRANSTRANSFER
ASE

(Marinomonas sp.
MED121) 		PF00348
(polyprenyl_synt) 		4 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.38A 5x1fW-4f62A:
undetectable		 5x1fW-4f62A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ina SACCHAROPINE
DEHYDROGENASE

(Wolinella
succinogenes) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		4 TYR A 103
MET A  93
THR A  91
LEU A  90
 None
 1.16A 5x1fW-4inaA:
undetectable		 5x1fW-4inaA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k0u LIPOPROTEIN OUTS

(Dickeya
dadantii) 		PF09691
(T2SS_PulS_OutS) 		4 ARG A 120
MET A 122
THR A 123
LEU A 126
 None
 1.07A 5x1fW-4k0uA:
undetectable		 5x1fW-4k0uA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA

(Neisseria
gonorrhoeae) 		PF01103
(Bac_surface_Ag)
PF07244
(POTRA) 		4 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 1.00A 5x1fW-4k3bA:
undetectable		 5x1fW-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l0o CYSTATHIONINE
GAMMA-SYNTHASE

(Helicobacter
pylori) 		no annotation 4 ARG H   2
MET H   3
THR H   5
LEU H   7
 None
 1.21A 5x1fW-4l0oH:
undetectable		 5x1fW-4l0oH:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q5y MATERNAL PROTEIN
TUDOR

(Drosophila
melanogaster) 		PF00567
(TUDOR) 		4 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.20A 5x1fW-4q5yA:
undetectable		 5x1fW-4q5yA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qtb MITOGEN-ACTIVATED
PROTEIN KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		4 ARG A 309
MET A 310
THR A 312
LEU A 311
 None
 1.37A 5x1fW-4qtbA:
undetectable		 5x1fW-4qtbA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8l UNCHARACTERIZED
PROTEIN

(Cavia porcellus) 		PF00710
(Asparaginase) 		4 ARG A 182
MET A 358
THR A 359
LEU A 360
 None
 1.14A 5x1fW-4r8lA:
undetectable		 5x1fW-4r8lA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rl6 SACCHAROPINE
DEHYDROGENASE

(Streptococcus
pneumoniae) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		4 TYR A 103
MET A  93
THR A  91
LEU A  90
 None
 1.20A 5x1fW-4rl6A:
undetectable		 5x1fW-4rl6A:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rm7 ACYL-COA
DEHYDROGENASE

(Slackia
heliotrinireducens) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.25A 5x1fW-4rm7A:
undetectable		 5x1fW-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rwt LEIOMODIN-2

(Homo sapiens) 		no annotation 4 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 0.96A 5x1fW-4rwtC:
undetectable		 5x1fW-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upk PHOSPHONATE
MONOESTER HYDROLASE

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase) 		4 TYR A 257
MET A 332
THR A 333
LEU A 406
 None
 1.18A 5x1fW-4upkA:
undetectable		 5x1fW-4upkA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uwa RYANODINE RECEPTOR 1

(Oryctolagus
cuniculus) 		PF00622
(SPRY)
PF01365
(RYDR_ITPR)
PF02026
(RyR)
PF02815
(MIR)
PF08709
(Ins145_P3_rec) 		4 TYR A 103
MET A 150
THR A 149
LEU A 171
 None
 1.31A 5x1fW-4uwaA:
undetectable		 5x1fW-4uwaA:
1.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yb9 SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 5

(Bos taurus) 		PF00083
(Sugar_tr) 		4 TYR D 149
ARG D  98
THR D 101
LEU D 103
 None
 0.95A 5x1fW-4yb9D:
undetectable		 5x1fW-4yb9D:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zi6 CYTOSOL
AMINOPEPTIDASE

(Helicobacter
pylori) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.54A 5x1fW-4zi6A:
undetectable		 5x1fW-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a96 POLYHEDRIN

(Cypovirus 14) 		PF17515
(CPV_Polyhedrin) 		4 ARG A 168
MET A 173
THR A 172
LEU A  61
 GTP  A1250 (-4.3A)
None
None
None
 1.16A 5x1fW-5a96A:
undetectable		 5x1fW-5a96A:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aov GLYOXYLATE REDUCTASE

(Pyrococcus
furiosus) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 TYR A 220
MET A 219
THR A 218
LEU A 214
 EDO  A1351 (-3.4A)
1PE  A1349 (-4.2A)
NAP  A1335 (-4.2A)
1PE  A1345 (-4.5A)
 1.31A 5x1fW-5aovA:
undetectable		 5x1fW-5aovA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b0n E3 UBIQUITIN-PROTEIN
LIGASE IPAH9.8

(Shigella
flexneri) 		PF12468
(TTSSLRR) 		4 ARG A 163
MET A 142
THR A 141
LEU A 122
 None
 1.32A 5x1fW-5b0nA:
undetectable		 5x1fW-5b0nA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dne L-ASPARAGINASE

(Cavia porcellus) 		PF00710
(Asparaginase) 		4 ARG A 182
MET A 358
THR A 359
LEU A 360
 None
 1.18A 5x1fW-5dneA:
undetectable		 5x1fW-5dneA:
6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ezr CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE

(Plasmodium
vivax) 		PF00027
(cNMP_binding)
PF00069
(Pkinase) 		4 ARG A 276
MET A 279
THR A 280
LEU A 283
 None
 0.97A 5x1fW-5ezrA:
undetectable		 5x1fW-5ezrA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f96 HEAVY CHAIN OF
ANTIBODY CH235.12

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 1.31A 5x1fW-5f96H:
undetectable		 5x1fW-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3

(Arabidopsis
thaliana) 		PF00311
(PEPcase) 		4 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.24A 5x1fW-5fdnA:
undetectable		 5x1fW-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g1n CAD PROTEIN

(Homo sapiens) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 TYR A2143
MET A2077
THR A2076
LEU A2101
 None
 1.28A 5x1fW-5g1nA:
undetectable		 5x1fW-5g1nA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gnc AVH146

(Phytophthora
sojae) 		no annotation 4 TYR A 232
MET A 228
THR A 227
LEU A 224
 None
 0.92A 5x1fW-5gncA:
undetectable		 5x1fW-5gncA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hcc COMPLEMENT C5

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF07677
(A2M_recep)
PF07678
(A2M_comp) 		4 TYR A1326
MET A1328
THR A1329
LEU A1309
 None
 1.37A 5x1fW-5hccA:
undetectable		 5x1fW-5hccA:
5.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hn7 FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE

(Plasmodium
vivax) 		PF00348
(polyprenyl_synt) 		4 TYR A 164
ARG A 185
THR A 183
LEU A 251
 None
 1.35A 5x1fW-5hn7A:
undetectable		 5x1fW-5hn7A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iig VACUOLAR TRANSPORTER
CHAPERONE 4

(Saccharomyces
cerevisiae) 		PF03105
(SPX)
PF09359
(VTC) 		4 ARG A 356
MET A 382
THR A 381
LEU A 380
 None
 0.98A 5x1fW-5iigA:
undetectable		 5x1fW-5iigA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ivl DEAD-BOX
ATP-DEPENDENT RNA
HELICASE CSHA

(Geobacillus
stearothermophilus) 		no annotation 4 TYR B 313
MET B 341
THR B 342
LEU B 220
 None
 1.39A 5x1fW-5ivlB:
undetectable		 5x1fW-5ivlB:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE GAMMA
SUBUNIT

(Aromatoleum
aromaticum) 		PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		4 TYR B 224
MET B 228
THR B 229
LEU B 232
 None
 0.64A 5x1fW-5l9wB:
undetectable		 5x1fW-5l9wB:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lki TCDA1

(Photorhabdus
luminescens) 		PF03538
(VRP1) 		4 ARG A1602
MET A1596
THR A1585
LEU A1584
 None
 1.23A 5x1fW-5lkiA:
undetectable		 5x1fW-5lkiA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mob SLPYL1_ABA

(Solanum
lycopersicum) 		PF10604
(Polyketide_cyc2) 		4 ARG A 109
MET A 110
THR A 111
LEU A 136
 None
 1.22A 5x1fW-5mobA:
undetectable		 5x1fW-5mobA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE

(Mus musculus) 		PF06090
(Ins_P5_2-kin) 		4 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.78A 5x1fW-5mwlA:
undetectable		 5x1fW-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1

(Burkholderia) 		no annotation 4 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.91A 5x1fW-5nm7G:
undetectable		 5x1fW-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nn8 LYSOSOMAL
ALPHA-GLUCOSIDASE

(Homo sapiens) 		no annotation 4 TYR A 685
MET A 391
THR A 392
LEU A 398
 NAG  A1007 (-4.2A)
None
None
None
 1.14A 5x1fW-5nn8A:
undetectable		 5x1fW-5nn8A:
5.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5non S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum) 		PF00407
(Bet_v_1) 		4 TYR A 108
MET A  97
THR A  98
LEU A  83
 None
93H  A 501 (-4.2A)
None
None
 1.27A 5x1fW-5nonA:
undetectable		 5x1fW-5nonA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o3w PEPTIDE CYCLASE 1

(Gypsophila
vaccaria) 		no annotation 4 TYR A 642
MET A 668
THR A 667
LEU A 664
 None
 1.36A 5x1fW-5o3wA:
undetectable		 5x1fW-5o3wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tzn KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE B
GLYCOPROTEIN FAMILY
PROTEIN M12

(Mus musculus;
Murid
betaherpesvirus
1) 		PF00059
(Lectin_C)
PF12216
(m04gp34like) 		4 TYR A 158
ARG F  49
MET A 163
THR A 161
 None
 1.39A 5x1fW-5tznA:
undetectable		 5x1fW-5tznA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uc2 DOMAIN OF UNKNOWN
FUNCTION DUF1849

(Brucella
abortus) 		PF08904
(DUF1849) 		5 TYR A 235
ARG A 236
MET A 252
THR A 251
LEU A 250
 None
 1.39A 5x1fW-5uc2A:
undetectable		 5x1fW-5uc2A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v6b PDZ
DOMAIN-CONTAINING
PROTEIN GIPC1

(Mus musculus) 		PF00595
(PDZ) 		4 ARG A 307
MET A 287
THR A 286
LEU A 283
 None
 1.17A 5x1fW-5v6bA:
undetectable		 5x1fW-5v6bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w95 CONSERVED MEMBRANE
PROTEIN OF
UNCHARACTERISED
FUNCTION

(Mycobacterium
tuberculosis) 		no annotation 4 ARG A 210
MET A 245
THR A 244
LEU A 243
 None
1PE  A 401 ( 4.3A)
None
None
 1.36A 5x1fW-5w95A:
undetectable		 5x1fW-5w95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x49 PROBABLE XAA-PRO
AMINOPEPTIDASE 3

(Homo sapiens) 		PF00557
(Peptidase_M24)
PF05195
(AMP_N) 		4 TYR A 339
ARG A 254
MET A 255
LEU A 488
 None
 1.22A 5x1fW-5x49A:
undetectable		 5x1fW-5x49A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbj FLAGELLAR
HOOK-ASSOCIATED
PROTEIN FLGK

(Campylobacter
jejuni) 		no annotation 4 ARG A 402
MET A 397
THR A 396
LEU A 360
 None
 1.27A 5x1fW-5xbjA:
undetectable		 5x1fW-5xbjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xk8 UNDECAPRENYL
DIPHOSPHATE SYNTHASE

(Streptomyces
sp. CNH189) 		no annotation 4 TYR A  26
MET A  29
THR A  30
LEU A  33
 None
 0.99A 5x1fW-5xk8A:
undetectable		 5x1fW-5xk8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fpe TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE

(Thermotoga
maritima) 		no annotation 4 TYR B 284
ARG B 278
THR B 247
LEU B 250
 None
 1.39A 5x1fW-6fpeB:
undetectable		 5x1fW-6fpeB:
undetectable