SIMILAR PATTERNS OF AMINO ACIDS FOR 5X1B_J_CHDJ101

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgs DNA LIGASE

(Thermus
filiformis) 		PF01653
(DNA_ligase_aden)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 ARG A 532
MET A 530
THR A 529
LEU A 503
 None
 1.18A 5x1bJ-1dgsA:
0.0		 5x1bJ-1dgsA:
6.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ep2 DIHYDROOROTATE
DEHYDROGENASE B
(PYRK SUBUNIT)

(Lactococcus
lactis) 		PF00175
(NAD_binding_1)
PF10418
(DHODB_Fe-S_bind) 		4 TYR B  71
MET B  23
THR B  68
LEU B  25
 None
 1.41A 5x1bJ-1ep2B:
0.0		 5x1bJ-1ep2B:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flo FLP RECOMBINASE

(Saccharomyces
cerevisiae) 		PF03930
(Flp_N)
PF05202
(Flp_C) 		4 ARG A 308
MET A 311
THR A 312
LEU A 315
 None
 0.85A 5x1bJ-1floA:
0.0		 5x1bJ-1floA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iw8 ACID PHOSPHATASE

(Shimwellia
blattae) 		PF01569
(PAP2) 		4 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.35A 5x1bJ-1iw8A:
0.2		 5x1bJ-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j32 ASPARTATE
AMINOTRANSFERASE

(Phormidium
lapideum) 		PF00155
(Aminotran_1_2) 		4 TYR A 366
ARG A 300
MET A 303
LEU A 307
 None
 1.23A 5x1bJ-1j32A:
0.0		 5x1bJ-1j32A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmu PROTEIN MU-1

(Reovirus sp.) 		PF05993
(Reovirus_M2) 		4 ARG B 377
MET B 495
THR B 494
LEU B 493
 None
 0.92A 5x1bJ-1jmuB:
0.0		 5x1bJ-1jmuB:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lrw METHANOL
DEHYDROGENASE
SUBUNIT 1

(Paracoccus
denitrificans) 		PF01011
(PQQ)
PF13360
(PQQ_2) 		4 ARG A 383
MET A 416
THR A 437
LEU A 436
 None
 1.17A 5x1bJ-1lrwA:
0.0		 5x1bJ-1lrwA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lrw METHANOL
DEHYDROGENASE
SUBUNIT 1

(Paracoccus
denitrificans) 		PF01011
(PQQ)
PF13360
(PQQ_2) 		4 ARG A 446
MET A 438
THR A 437
LEU A 436
 None
 1.32A 5x1bJ-1lrwA:
0.0		 5x1bJ-1lrwA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rxm DNA POLYMERASE
SLIDING CLAMP

(Archaeoglobus
fulgidus) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 ARG A 162
MET A 176
THR A 177
LEU A 181
 None
 1.32A 5x1bJ-1rxmA:
undetectable		 5x1bJ-1rxmA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s4f RNA-DEPENDENT RNA
POLYMERASE

(Pestivirus A) 		PF00998
(RdRP_3) 		4 TYR A 256
MET A 384
THR A 385
LEU A 358
 None
 1.41A 5x1bJ-1s4fA:
0.0		 5x1bJ-1s4fA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3i GLUTATHIONE
S-TRANSFERASE 28 KDA

(Schistosoma
mansoni) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A  92
MET A  85
THR A 157
LEU A 158
 None
 1.24A 5x1bJ-1u3iA:
undetectable		 5x1bJ-1u3iA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uf2 CORE PROTEIN P3

(Rice dwarf
virus) 		PF09231
(RDV-p3) 		4 ARG A 122
MET A 765
THR A 766
LEU A 768
 None
 1.26A 5x1bJ-1uf2A:
undetectable		 5x1bJ-1uf2A:
4.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1usy ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT

(Thermotoga
maritima) 		PF13393
(tRNA-synt_His) 		4 ARG C 186
MET C 195
THR C 194
LEU C 192
 None
 1.42A 5x1bJ-1usyC:
undetectable		 5x1bJ-1usyC:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9p DNA LIGASE

(Thermus
filiformis) 		PF01653
(DNA_ligase_aden)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 ARG A 535
MET A 533
THR A 532
LEU A 506
 None
 1.12A 5x1bJ-1v9pA:
undetectable		 5x1bJ-1v9pA:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcz RNASE NGR3

(Nicotiana
glutinosa) 		PF00445
(Ribonuclease_T2) 		4 ARG A 116
MET A  72
THR A  71
LEU A  68
 None
 1.48A 5x1bJ-1vczA:
undetectable		 5x1bJ-1vczA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yks GENOME POLYPROTEIN
[CONTAINS:
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT]

(Yellow fever
virus) 		PF00271
(Helicase_C)
PF07652
(Flavi_DEAD) 		4 ARG A 538
MET A 274
THR A 271
LEU A 270
 None
 1.23A 5x1bJ-1yksA:
undetectable		 5x1bJ-1yksA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yx0 HYPOTHETICAL PROTEIN
YSNE

(Bacillus
subtilis) 		PF00583
(Acetyltransf_1) 		4 TYR A 131
MET A 147
THR A 148
LEU A 109
 None
 1.29A 5x1bJ-1yx0A:
undetectable		 5x1bJ-1yx0A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ash QUEUINE
TRNA-RIBOSYLTRANSFER
ASE

(Thermotoga
maritima) 		PF01702
(TGT) 		4 ARG A 255
MET A 224
THR A 221
LEU A 220
 None
 1.17A 5x1bJ-2ashA:
undetectable		 5x1bJ-2ashA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 TYR A1179
ARG A1205
THR A1207
LEU A1210
 None
 1.35A 5x1bJ-2b39A:
undetectable		 5x1bJ-2b39A:
3.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cai GLUTATHIONE
S-TRANSFERASE 28 KDA

(Schistosoma
haematobium) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A  92
MET A  85
THR A 157
LEU A 158
 PG4  A1218 (-3.6A)
None
None
None
 1.20A 5x1bJ-2caiA:
undetectable		 5x1bJ-2caiA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2diq TUDOR AND KH
DOMAIN-CONTAINING
PROTEIN

(Homo sapiens) 		PF00567
(TUDOR) 		4 TYR A  23
ARG A  85
MET A  19
LEU A  15
 None
 1.27A 5x1bJ-2diqA:
undetectable		 5x1bJ-2diqA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fe8 REPLICASE
POLYPROTEIN 1AB

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF08715
(Viral_protease) 		4 ARG A 167
MET A 170
THR A 171
LEU A 174
 None
 1.26A 5x1bJ-2fe8A:
undetectable		 5x1bJ-2fe8A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fqz R.ECL18KI

(Enterobacter
cloacae) 		PF09019
(EcoRII-C) 		4 TYR A 205
MET A 177
THR A 176
LEU A 258
 None
 1.43A 5x1bJ-2fqzA:
undetectable		 5x1bJ-2fqzA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jii SERINE/THREONINE-PRO
TEIN KINASE VRK3
MOLECULE: VACCINIA
RELATED KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 141
MET A 145
THR A 146
LEU A 149
 None
 1.42A 5x1bJ-2jiiA:
undetectable		 5x1bJ-2jiiA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jii SERINE/THREONINE-PRO
TEIN KINASE VRK3
MOLECULE: VACCINIA
RELATED KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 141
MET A 145
THR A 147
LEU A 149
 None
 1.35A 5x1bJ-2jiiA:
undetectable		 5x1bJ-2jiiA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ocd L-ASPARAGINASE I

(Vibrio cholerae) 		PF00710
(Asparaginase) 		4 ARG A 157
MET A 335
THR A 336
LEU A 337
 None
 1.05A 5x1bJ-2ocdA:
undetectable		 5x1bJ-2ocdA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rb9 HYPE PROTEIN

(Escherichia
coli) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 TYR A  93
ARG A  92
MET A 150
LEU A  53
 None
 1.43A 5x1bJ-2rb9A:
undetectable		 5x1bJ-2rb9A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdx MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME,
PUTATIVE

(Roseovarius
nubinhibens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 TYR A 159
MET A 135
THR A 320
LEU A 342
 None
 1.47A 5x1bJ-2rdxA:
undetectable		 5x1bJ-2rdxA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhm PUTATIVE KINASE

(Chloroflexus
aurantiacus) 		PF13671
(AAA_33) 		4 TYR A  66
MET A  94
THR A  91
LEU A 157
 None
 1.30A 5x1bJ-2rhmA:
undetectable		 5x1bJ-2rhmA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2sxl SEX-LETHAL PROTEIN

(Drosophila
melanogaster) 		PF00076
(RRM_1) 		4 ARG A  37
MET A  15
THR A  16
LEU A  20
 None
 1.36A 5x1bJ-2sxlA:
undetectable		 5x1bJ-2sxlA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vfv XYLITOL OXIDASE

(Streptomyces
coelicolor) 		PF01565
(FAD_binding_4)
PF04030
(ALO) 		4 TYR A 208
ARG A 232
MET A 182
THR A 230
 None
 1.43A 5x1bJ-2vfvA:
undetectable		 5x1bJ-2vfvA:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vq5 S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum) 		PF00407
(Bet_v_1) 		4 TYR A 108
MET A  97
THR A  98
LEU A  83
 None
HBA  A1203 (-3.4A)
None
None
 1.27A 5x1bJ-2vq5A:
undetectable		 5x1bJ-2vq5A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w6d DYNAMIN FAMILY
PROTEIN

(Nostoc
punctiforme) 		PF00350
(Dynamin_N) 		4 TYR A 422
ARG A 421
THR A 414
LEU A 411
 None
CPL  A1701 (-4.4A)
CPL  A1701 (-1.4A)
None
 1.26A 5x1bJ-2w6dA:
undetectable		 5x1bJ-2w6dA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wn2 DISCOIDIN-1 SUBUNIT
A

(Dictyostelium
discoideum) 		PF00754
(F5_F8_type_C)
PF09458
(H_lectin) 		4 ARG A 128
MET A  72
THR A 151
LEU A   6
 None
 1.06A 5x1bJ-2wn2A:
undetectable		 5x1bJ-2wn2A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN

(Bordetella
bronchiseptica) 		PF04183
(IucA_IucC)
PF06276
(FhuF) 		4 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.37A 5x1bJ-2x0qA:
undetectable		 5x1bJ-2x0qA:
11.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos taurus) 		PF02238
(COX7a) 		5 TYR J  32
ARG J  33
MET J  36
THR J  37
LEU J  40
 None
 0.77A 5x1bJ-2y69J:
7.6		 5x1bJ-2y69J:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ziu MUS81 PROTEIN

(Danio rerio) 		PF02732
(ERCC4) 		4 TYR A 471
MET A 475
THR A 476
LEU A 479
 None
 0.59A 5x1bJ-2ziuA:
undetectable		 5x1bJ-2ziuA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a75 GAMMA-GLUTAMYLTRANSP
EPTIDASE LARGE CHAIN

(Bacillus
subtilis) 		PF01019
(G_glu_transpept) 		4 TYR A 332
MET A 328
THR A 327
LEU A 324
 None
 1.06A 5x1bJ-3a75A:
undetectable		 5x1bJ-3a75A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmm UBIQUITIN-ACTIVATING
ENZYME E1 1

(Saccharomyces
cerevisiae) 		PF00899
(ThiF)
PF09358
(E1_UFD)
PF10585
(UBA_e1_thiolCys)
PF16190
(E1_FCCH)
PF16191
(E1_4HB) 		4 TYR A 959
MET A1001
THR A1000
LEU A1024
 None
 1.09A 5x1bJ-3cmmA:
undetectable		 5x1bJ-3cmmA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebb PHOSPHOLIPASE
A2-ACTIVATING
PROTEIN

(Homo sapiens) 		PF08324
(PUL) 		4 TYR A 709
ARG A 680
MET A 676
LEU A 675
 None
 1.21A 5x1bJ-3ebbA:
undetectable		 5x1bJ-3ebbA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebv CHINITASE A

(Streptomyces
coelicolor) 		PF00704
(Glyco_hydro_18) 		4 TYR A 162
MET A 148
THR A 147
LEU A 146
 None
 1.37A 5x1bJ-3ebvA:
undetectable		 5x1bJ-3ebvA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gf6 UNCHARACTERIZED
BACTERIAL
LIPOPROTEIN

(Bacteroides
thetaiotaomicron) 		PF12956
(DUF3845) 		4 TYR A  68
MET A 105
THR A 104
LEU A 103
 None
 1.30A 5x1bJ-3gf6A:
undetectable		 5x1bJ-3gf6A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h14 AMINOTRANSFERASE,
CLASSES I AND II

(Ruegeria
pomeroyi) 		PF00155
(Aminotran_1_2) 		4 TYR A 361
ARG A 292
MET A 295
LEU A 299
 None
 1.45A 5x1bJ-3h14A:
undetectable		 5x1bJ-3h14A:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4z MALTOSE-BINDING
PERIPLASMIC PROTEIN
FUSED WITH ALLERGEN
DERP7

(Escherichia
coli;
Dermatophagoides
pteronyssinus) 		PF13416
(SBP_bac_8)
PF16984
(Grp7_allergen) 		4 ARG A1195
MET A1198
THR A1199
LEU A1202
 None
 1.28A 5x1bJ-3h4zA:
undetectable		 5x1bJ-3h4zA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i7d SUGAR PHOSPHATE
ISOMERASE

(Ruegeria
pomeroyi) 		PF07883
(Cupin_2) 		4 TYR A 128
MET A 133
THR A 145
LEU A 152
 CAC  A 164 (-4.3A)
None
None
None
 1.40A 5x1bJ-3i7dA:
undetectable		 5x1bJ-3i7dA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ig2 PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Bacteroides
fragilis) 		no annotation 4 TYR A 593
ARG A 562
MET A 561
THR A 531
 None
 1.17A 5x1bJ-3ig2A:
undetectable		 5x1bJ-3ig2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ila RYANODINE RECEPTOR 1

(Oryctolagus
cuniculus) 		PF08709
(Ins145_P3_rec) 		4 TYR A 103
MET A 150
THR A 149
LEU A 171
 None
 1.44A 5x1bJ-3ilaA:
undetectable		 5x1bJ-3ilaA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1

(Homo sapiens) 		PF01233
(NMT)
PF02799
(NMT_C) 		4 ARG A 322
MET A 320
THR A 319
LEU A 314
 None
 1.37A 5x1bJ-3iu1A:
undetectable		 5x1bJ-3iu1A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kny HYPOTHETICAL PROTEIN
BT_3535

(Bacteroides
thetaiotaomicron) 		no annotation 4 TYR A  69
ARG A  68
MET A  65
THR A  64
 None
 1.38A 5x1bJ-3knyA:
undetectable		 5x1bJ-3knyA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
4

(Mus musculus) 		PF06470
(SMC_hinge) 		4 TYR B 707
ARG B 711
THR B 713
LEU B 714
 GOL  B 403 (-4.4A)
GOL  B 403 (-3.8A)
None
None
 1.19A 5x1bJ-3l51B:
undetectable		 5x1bJ-3l51B:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mwe ATP-CITRATE SYNTHASE

(Homo sapiens) 		PF16114
(Citrate_bind) 		4 TYR A 319
MET A 278
THR A 277
LEU A 338
 None
 1.39A 5x1bJ-3mweA:
undetectable		 5x1bJ-3mweA:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntk MATERNAL PROTEIN
TUDOR

(Drosophila
melanogaster) 		PF00567
(TUDOR) 		4 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.22A 5x1bJ-3ntkA:
undetectable		 5x1bJ-3ntkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 ARG A 297
MET A 300
THR A 301
LEU A 305
 None
 1.39A 5x1bJ-3o9pA:
undetectable		 5x1bJ-3o9pA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pr1 PROBABLE GTP-BINDING
PROTEIN ENGB

(Thermotoga
maritima) 		PF01926
(MMR_HSR1) 		4 ARG A 115
MET A 143
THR A 141
LEU A 140
 None
 1.46A 5x1bJ-3pr1A:
undetectable		 5x1bJ-3pr1A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6v BETA-LACTAMASE

(Serratia
fonticola) 		PF00753
(Lactamase_B) 		4 TYR A 191
MET A 141
THR A 142
LEU A 145
 None
 0.92A 5x1bJ-3q6vA:
undetectable		 5x1bJ-3q6vA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qp9 TYPE I POLYKETIDE
SYNTHASE PIKAII

(Streptomyces
venezuelae) 		PF08659
(KR) 		4 ARG A 181
MET A 187
THR A 188
LEU A 191
 None
 1.33A 5x1bJ-3qp9A:
undetectable		 5x1bJ-3qp9A:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr5 PEPTIDE CHAIN
RELEASE FACTOR 3

(Coxiella
burnetii) 		PF00009
(GTP_EFTU)
PF16658
(RF3_C) 		4 TYR A 242
MET A 135
THR A 136
LEU A 107
 None
 1.45A 5x1bJ-3tr5A:
undetectable		 5x1bJ-3tr5A:
6.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uv1 DER F 7 ALLERGEN

(Dermatophagoides
farinae) 		PF16984
(Grp7_allergen) 		4 ARG A 178
MET A 181
THR A 182
LEU A 185
 None
 1.12A 5x1bJ-3uv1A:
undetectable		 5x1bJ-3uv1A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr1 PEPTIDE CHAIN
RELEASE FACTOR 3

(Desulfovibrio
vulgaris) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF16658
(RF3_C) 		4 TYR A 244
MET A 137
THR A 138
LEU A 109
 None
 1.34A 5x1bJ-3vr1A:
undetectable		 5x1bJ-3vr1A:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w21 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Burkholderia
ambifaria) 		no annotation 4 ARG A 256
MET A 258
THR A 257
LEU A 182
 None
None
AKG  A 302 (-3.1A)
None
 1.30A 5x1bJ-3w21A:
undetectable		 5x1bJ-3w21A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wel ALPHA-GLUCOSIDASE

(Beta vulgaris) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF16863
(NtCtMGAM_N) 		4 TYR A 620
MET A 583
THR A 582
LEU A 584
 None
 1.24A 5x1bJ-3welA:
undetectable		 5x1bJ-3welA:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eqv INVERTASE 2

(Saccharomyces
cerevisiae) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 TYR A 358
MET A 493
THR A 494
LEU A 391
 None
 1.11A 5x1bJ-4eqvA:
undetectable		 5x1bJ-4eqvA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4es7 PROTEIN AMBP

(Homo sapiens) 		PF00061
(Lipocalin) 		4 TYR A  72
MET A  55
THR A  56
LEU A  42
 None
 1.41A 5x1bJ-4es7A:
undetectable		 5x1bJ-4es7A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f62 GERANYLTRANSTRANSFER
ASE

(Marinomonas sp.
MED121) 		PF00348
(polyprenyl_synt) 		4 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.16A 5x1bJ-4f62A:
undetectable		 5x1bJ-4f62A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ina SACCHAROPINE
DEHYDROGENASE

(Wolinella
succinogenes) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		4 TYR A 103
MET A  93
THR A  91
LEU A  90
 None
 1.18A 5x1bJ-4inaA:
undetectable		 5x1bJ-4inaA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA

(Neisseria
gonorrhoeae) 		PF01103
(Bac_surface_Ag)
PF07244
(POTRA) 		4 TYR A 296
ARG A 298
MET A 301
THR A 302
 None
 1.28A 5x1bJ-4k3bA:
undetectable		 5x1bJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA

(Neisseria
gonorrhoeae) 		PF01103
(Bac_surface_Ag)
PF07244
(POTRA) 		4 TYR A 296
MET A 301
THR A 302
LEU A 305
 None
 0.96A 5x1bJ-4k3bA:
undetectable		 5x1bJ-4k3bA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ovd PEPTIDOGLYCAN
GLYCOSYLTRANSFERASE

(Atopobium
parvulum) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 ARG A 355
MET A 478
THR A 479
LEU A 475
 None
 1.44A 5x1bJ-4ovdA:
undetectable		 5x1bJ-4ovdA:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q5y MATERNAL PROTEIN
TUDOR

(Drosophila
melanogaster) 		PF00567
(TUDOR) 		4 TYR A2452
MET A2376
THR A2377
LEU A2380
 None
 1.22A 5x1bJ-4q5yA:
undetectable		 5x1bJ-4q5yA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qdg PUTATIVE ADHESIN

(Bacteroides
thetaiotaomicron) 		PF08842
(Mfa2) 		4 TYR A  93
ARG A  94
MET A  95
LEU A  97
 None
 1.39A 5x1bJ-4qdgA:
undetectable		 5x1bJ-4qdgA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlo HOMOSERINE
O-ACETYLTRANSFERASE

(Staphylococcus
aureus) 		PF00561
(Abhydrolase_1) 		4 ARG A 276
MET A 262
THR A 261
LEU A 260
 None
 1.31A 5x1bJ-4qloA:
undetectable		 5x1bJ-4qloA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8l UNCHARACTERIZED
PROTEIN

(Cavia porcellus) 		PF00710
(Asparaginase) 		4 ARG A 182
MET A 358
THR A 359
LEU A 360
 None
 1.01A 5x1bJ-4r8lA:
undetectable		 5x1bJ-4r8lA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh0 SPORE PHOTOPRODUCT
LYASE

(Geobacillus
thermodenitrificans) 		no annotation 4 TYR A 327
ARG A 326
MET A 324
LEU A 320
 None
 1.24A 5x1bJ-4rh0A:
undetectable		 5x1bJ-4rh0A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rm7 ACYL-COA
DEHYDROGENASE

(Slackia
heliotrinireducens) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 TYR A 322
MET A 295
THR A 293
LEU A 292
 None
 1.25A 5x1bJ-4rm7A:
undetectable		 5x1bJ-4rm7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rwt LEIOMODIN-2

(Homo sapiens) 		no annotation 4 ARG C 309
MET C 312
THR C 313
LEU C 316
 None
 1.29A 5x1bJ-4rwtC:
undetectable		 5x1bJ-4rwtC:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upk PHOSPHONATE
MONOESTER HYDROLASE

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase) 		4 TYR A 257
MET A 332
THR A 333
LEU A 406
 None
 1.21A 5x1bJ-4upkA:
undetectable		 5x1bJ-4upkA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uwa RYANODINE RECEPTOR 1

(Oryctolagus
cuniculus) 		PF00622
(SPRY)
PF01365
(RYDR_ITPR)
PF02026
(RyR)
PF02815
(MIR)
PF08709
(Ins145_P3_rec) 		4 TYR A 103
MET A 150
THR A 149
LEU A 171
 None
 1.34A 5x1bJ-4uwaA:
undetectable		 5x1bJ-4uwaA:
1.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z6g MICROTUBULE-ACTIN
CROSS-LINKING FACTOR
1, ISOFORMS 1/2/3/5

(Homo sapiens) 		PF00307
(CH) 		4 TYR A 323
ARG A 382
MET A 379
LEU A 375
 None
 1.33A 5x1bJ-4z6gA:
undetectable		 5x1bJ-4z6gA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zi6 CYTOSOL
AMINOPEPTIDASE

(Helicobacter
pylori) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.60A 5x1bJ-4zi6A:
undetectable		 5x1bJ-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah5 LEUCINE--TRNA LIGASE

(Agrobacterium
tumefaciens) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2) 		4 TYR A 153
ARG A 185
THR A 264
LEU A 266
 None
 1.29A 5x1bJ-5ah5A:
undetectable		 5x1bJ-5ah5A:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dne L-ASPARAGINASE

(Cavia porcellus) 		PF00710
(Asparaginase) 		4 ARG A 182
MET A 358
THR A 359
LEU A 360
 None
 1.15A 5x1bJ-5dneA:
undetectable		 5x1bJ-5dneA:
6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5evy SALICYLATE
HYDROXYLASE

(Pseudomonas
putida) 		PF01494
(FAD_binding_3) 		4 TYR X 356
ARG X 360
MET X 335
LEU X  20
 None
 1.17A 5x1bJ-5evyX:
undetectable		 5x1bJ-5evyX:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ezr CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE

(Plasmodium
vivax) 		PF00027
(cNMP_binding)
PF00069
(Pkinase) 		4 ARG A 276
MET A 279
THR A 280
LEU A 283
 None
 0.87A 5x1bJ-5ezrA:
undetectable		 5x1bJ-5ezrA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f96 HEAVY CHAIN OF
ANTIBODY CH235.12

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ARG H  82
MET H  18
THR H  19
LEU H  20
 None
 0.90A 5x1bJ-5f96H:
undetectable		 5x1bJ-5f96H:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3

(Arabidopsis
thaliana) 		PF00311
(PEPcase) 		4 ARG A 666
MET A 634
THR A 633
LEU A 632
 None
 1.28A 5x1bJ-5fdnA:
undetectable		 5x1bJ-5fdnA:
4.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g1n CAD PROTEIN

(Homo sapiens) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 TYR A2143
MET A2077
THR A2076
LEU A2101
 None
 1.30A 5x1bJ-5g1nA:
undetectable		 5x1bJ-5g1nA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hcc COMPLEMENT C5

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF07677
(A2M_recep)
PF07678
(A2M_comp) 		4 TYR A1326
MET A1328
THR A1329
LEU A1309
 None
 1.38A 5x1bJ-5hccA:
undetectable		 5x1bJ-5hccA:
5.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j44 SERINE PROTEASE SEPA
AUTOTRANSPORTER

(Shigella
flexneri) 		PF02395
(Peptidase_S6) 		4 TYR A 701
MET A 652
THR A 633
LEU A 634
 None
 1.48A 5x1bJ-5j44A:
undetectable		 5x1bJ-5j44A:
5.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9w ACETOPHENONE
CARBOXYLASE GAMMA
SUBUNIT

(Aromatoleum
aromaticum) 		PF01968
(Hydantoinase_A)
PF05378
(Hydant_A_N) 		4 TYR B 224
MET B 228
THR B 229
LEU B 232
 None
 0.67A 5x1bJ-5l9wB:
undetectable		 5x1bJ-5l9wB:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN

(Bacteroides
thetaiotaomicron) 		PF17132
(Glyco_hydro_106) 		4 ARG A 775
MET A 776
THR A 777
LEU A 778
 None
 1.19A 5x1bJ-5mqmA:
undetectable		 5x1bJ-5mqmA:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5non S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum) 		PF00407
(Bet_v_1) 		4 TYR A 108
MET A  97
THR A  98
LEU A  83
 None
93H  A 501 (-4.2A)
None
None
 1.24A 5x1bJ-5nonA:
undetectable		 5x1bJ-5nonA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o3w PEPTIDE CYCLASE 1

(Gypsophila
vaccaria) 		no annotation 4 TYR A 642
MET A 668
THR A 667
LEU A 664
 None
 1.38A 5x1bJ-5o3wA:
undetectable		 5x1bJ-5o3wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5te1 ATP-CITRATE SYNTHASE

(Homo sapiens) 		PF00549
(Ligase_CoA)
PF02629
(CoA_binding)
PF16114
(Citrate_bind) 		4 TYR A 319
MET A 278
THR A 277
LEU A 338
 None
 1.37A 5x1bJ-5te1A:
undetectable		 5x1bJ-5te1A:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u30 CRISPR-ASSOCIATED
ENDONUCLEASE C2C1

(Alicyclobacillus
acidoterrestris) 		no annotation 4 ARG A 534
MET A 893
THR A 892
LEU A 846
 None
 1.15A 5x1bJ-5u30A:
undetectable		 5x1bJ-5u30A:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uc2 DOMAIN OF UNKNOWN
FUNCTION DUF1849

(Brucella
abortus) 		PF08904
(DUF1849) 		4 TYR A 254
MET A 252
THR A 251
LEU A 250
 None
 1.43A 5x1bJ-5uc2A:
undetectable		 5x1bJ-5uc2A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wvr KLLA0C04147P

(Kluyveromyces
lactis) 		PF01237
(Oxysterol_BP) 		4 ARG A 861
MET A 862
THR A 863
LEU A 864
 None
None
None
CLR  A1301 (-4.2A)
 1.25A 5x1bJ-5wvrA:
undetectable		 5x1bJ-5wvrA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x49 PROBABLE XAA-PRO
AMINOPEPTIDASE 3

(Homo sapiens) 		PF00557
(Peptidase_M24)
PF05195
(AMP_N) 		4 TYR A 339
ARG A 254
MET A 255
LEU A 488
 None
 1.37A 5x1bJ-5x49A:
undetectable		 5x1bJ-5x49A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xk8 UNDECAPRENYL
DIPHOSPHATE SYNTHASE

(Streptomyces
sp. CNH189) 		no annotation 4 TYR A  26
MET A  29
THR A  30
LEU A  33
 None
 0.99A 5x1bJ-5xk8A:
undetectable		 5x1bJ-5xk8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3r PIEZO-TYPE
MECHANOSENSITIVE ION
CHANNEL COMPONENT 1

(Mus musculus) 		no annotation 4 ARG A2544
MET A2539
THR A2538
LEU A2532
 None
 1.27A 5x1bJ-6b3rA:
undetectable		 5x1bJ-6b3rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f1v CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1

(Homo sapiens) 		no annotation 4 ARG f 664
MET f 662
THR f 659
LEU f 658
 None
 1.44A 5x1bJ-6f1vf:
undetectable		 5x1bJ-6f1vf:
undetectable