SIMILAR PATTERNS OF AMINO ACIDS FOR 5X1B_C_CHDC304_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c0a ASPARTYL TRNA
SYNTHETASE

(Escherichia
coli) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		3 ARG A 317
PHE A 393
LEU A 292
 None
 0.81A 5x1bC-1c0aA:
0.0		 5x1bC-1c0aA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1c METHYLMALONYL-COA
MUTASE ALPHA CHAIN

(Propionibacterium
freudenreichii) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding) 		3 ARG A 305
PHE A 287
LEU A 301
 None
DCA  A 801 ( 4.5A)
None
 0.83A 5x1bC-1e1cA:
undetectable		 5x1bC-1e1cA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eth TRIACYLGLYCEROL
ACYL-HYDROLASE

(Sus scrofa) 		PF00151
(Lipase)
PF01477
(PLAT) 		3 ARG A 165
PHE A 132
LEU A   8
 BMA  A 454 (-3.4A)
None
None
 0.72A 5x1bC-1ethA:
0.5		 5x1bC-1ethA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ewr DNA MISMATCH REPAIR
PROTEIN MUTS

(Thermus
aquaticus) 		PF00488
(MutS_V)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		3 ARG A 687
PHE A 693
LEU A 650
 None
 0.52A 5x1bC-1ewrA:
undetectable		 5x1bC-1ewrA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i31 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50

(Rattus
norvegicus) 		PF00928
(Adap_comp_sub) 		3 ARG A 162
PHE A 407
LEU A 206
 None
 0.39A 5x1bC-1i31A:
undetectable		 5x1bC-1i31A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iqc DI-HEME PEROXIDASE

(Nitrosomonas
europaea) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		3 ARG A  30
PHE A  26
LEU A 294
 None
HEM  A 401 ( 4.9A)
None
 0.77A 5x1bC-1iqcA:
undetectable		 5x1bC-1iqcA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jkw CYCLIN H

(Homo sapiens) 		PF00134
(Cyclin_N)
PF16899
(Cyclin_C_2) 		3 ARG A 102
PHE A 110
LEU A 129
 None
 0.93A 5x1bC-1jkwA:
0.6		 5x1bC-1jkwA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1juh QUERCETIN
2,3-DIOXYGENASE

(Aspergillus
japonicus) 		no annotation 3 ARG A  15
PHE A 309
LEU A   5
 None
 0.93A 5x1bC-1juhA:
undetectable		 5x1bC-1juhA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kl7 THREONINE SYNTHASE

(Saccharomyces
cerevisiae) 		PF00291
(PALP)
PF14821
(Thr_synth_N) 		3 ARG A 319
PHE A 311
LEU A 370
 None
 0.89A 5x1bC-1kl7A:
undetectable		 5x1bC-1kl7A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lsh LIPOVITELLIN (LV-1N,
LV-1C)

(Ichthyomyzon
unicuspis) 		PF01347
(Vitellogenin_N)
PF09172
(DUF1943) 		3 ARG A 940
PHE A  83
LEU A  86
 None
 0.73A 5x1bC-1lshA:
0.0		 5x1bC-1lshA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nne DNA MISMATCH REPAIR
PROTEIN MUTS

(Thermus
aquaticus) 		PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		3 ARG A 687
PHE A 693
LEU A 650
 None
 0.67A 5x1bC-1nneA:
2.2		 5x1bC-1nneA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p43 ENOLASE 1

(Saccharomyces
cerevisiae) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		3 ARG A 391
PHE A 425
LEU A 436
 None
 0.95A 5x1bC-1p43A:
undetectable		 5x1bC-1p43A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p43 ENOLASE 1

(Saccharomyces
cerevisiae) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		3 ARG A 391
PHE A 430
LEU A 436
 None
 0.87A 5x1bC-1p43A:
undetectable		 5x1bC-1p43A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qrd QUINONE-REDUCTASE

(Rattus rattus) 		PF02525
(Flavodoxin_2) 		3 ARG A  14
PHE A  17
LEU A   9
 None
FAD  A 274 (-4.9A)
None
 0.95A 5x1bC-1qrdA:
undetectable		 5x1bC-1qrdA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r5n EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
GTP-BINDING SUBUNIT

(Schizosaccharomyces
pombe) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3) 		3 ARG A 308
PHE A 318
LEU A 321
 None
 0.77A 5x1bC-1r5nA:
undetectable		 5x1bC-1r5nA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rz6 CYTOCHROME C
PEROXIDASE

(Marinobacter
hydrocarbonoclasticus) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		3 ARG A  42
PHE A  38
LEU A 311
 None
 0.94A 5x1bC-1rz6A:
undetectable		 5x1bC-1rz6A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tyd TYROSYL-TRNA
SYNTHETASE

(Geobacillus
stearothermophilus) 		PF00579
(tRNA-synt_1b) 		3 ARG E 107
PHE E 270
LEU E 241
 None
 0.93A 5x1bC-1tydE:
undetectable		 5x1bC-1tydE:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ul4 SQUAMOSA PROMOTER
BINDING PROTEIN-LIKE
4

(Arabidopsis
thaliana) 		PF03110
(SBP) 		3 ARG A  93
PHE A  86
LEU A 104
 None
 0.92A 5x1bC-1ul4A:
undetectable		 5x1bC-1ul4A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uw4 REGULATOR OF
NONSENSE TRANSCRIPTS
2

(Homo sapiens) 		PF02854
(MIF4G) 		3 ARG B 984
PHE B 949
LEU B 942
 None
 0.94A 5x1bC-1uw4B:
undetectable		 5x1bC-1uw4B:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x0a MALATE/L-LACTATE
DEHYDROGENASE FAMILY
PROTEIN

(Thermus
thermophilus) 		PF02615
(Ldh_2) 		3 ARG A 111
PHE A 262
LEU A  77
 None
 0.95A 5x1bC-1x0aA:
undetectable		 5x1bC-1x0aA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yg2 GENE ACTIVATOR APHA

(Vibrio cholerae) 		PF03551
(PadR)
PF10400
(Vir_act_alpha_C) 		3 ARG A 112
PHE A  96
LEU A 172
 None
 0.94A 5x1bC-1yg2A:
3.8		 5x1bC-1yg2A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zzh CYTOCHROME C
PEROXIDASE

(Rhodobacter
capsulatus) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		3 ARG A  45
PHE A  41
LEU A 314
 None
 0.88A 5x1bC-1zzhA:
undetectable		 5x1bC-1zzhA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aj7 HYPOTHETICAL PROTEIN
BH3618

(Bacillus
halodurans) 		PF02623
(FliW) 		3 ARG A  18
PHE A  35
LEU A  38
 None
 0.69A 5x1bC-2aj7A:
undetectable		 5x1bC-2aj7A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bp5 CLATHRIN COAT
ASSEMBLY PROTEIN
AP50

(Rattus
norvegicus) 		PF00928
(Adap_comp_sub) 		3 ARG M 162
PHE M 407
LEU M 206
 None
 0.49A 5x1bC-2bp5M:
undetectable		 5x1bC-2bp5M:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1u DI-HAEM CYTOCHROME C
PEROXIDASE

(Paracoccus
pantotrophus) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		3 ARG A  56
PHE A  52
LEU A 325
 None
 0.89A 5x1bC-2c1uA:
undetectable		 5x1bC-2c1uA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cge ATP-DEPENDENT
MOLECULAR CHAPERONE
HSP82

(Saccharomyces
cerevisiae) 		PF00183
(HSP90) 		3 ARG A 346
PHE A 349
LEU A 376
 None
 0.81A 5x1bC-2cgeA:
undetectable		 5x1bC-2cgeA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ess ACYL-ACP
THIOESTERASE

(Bacteroides
thetaiotaomicron) 		PF01643
(Acyl-ACP_TE) 		3 ARG A 197
PHE A  78
LEU A  68
 None
 0.74A 5x1bC-2essA:
undetectable		 5x1bC-2essA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hcf HYDROLASE, HALOACID
DEHALOGENASE-LIKE
FAMILY

(Chlorobaculum
tepidum) 		PF13419
(HAD_2) 		3 ARG A  98
PHE A 217
LEU A  93
 None
 0.88A 5x1bC-2hcfA:
undetectable		 5x1bC-2hcfA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i5i UPF0249 PROTEIN
EF_3048

(Enterococcus
faecalis) 		PF04794
(YdjC) 		3 ARG A 250
PHE A 183
LEU A 194
 None
 0.95A 5x1bC-2i5iA:
undetectable		 5x1bC-2i5iA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2opt ACTII PROTEIN

(Streptomyces
coelicolor) 		PF00440
(TetR_N)
PF02909
(TetR_C) 		3 ARG A  75
PHE A  83
LEU A  49
 None
 0.60A 5x1bC-2optA:
3.0		 5x1bC-2optA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pkg SMALL T ANTIGEN

(Macaca mulatta
polyomavirus 1) 		PF02380
(Papo_T_antigen) 		3 ARG C 119
PHE C 144
LEU C 115
 None
 0.86A 5x1bC-2pkgC:
undetectable		 5x1bC-2pkgC:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qng UNCHARACTERIZED
PROTEIN SAV2460

(Streptomyces
avermitilis) 		PF02342
(TerD) 		3 ARG A 145
PHE A  36
LEU A  85
 None
 0.73A 5x1bC-2qngA:
undetectable		 5x1bC-2qngA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ts1 TYROSYL-TRNA
SYNTHETASE

(Geobacillus
stearothermophilus) 		PF00579
(tRNA-synt_1b) 		3 ARG A 107
PHE A 270
LEU A 241
 None
 0.92A 5x1bC-2ts1A:
undetectable		 5x1bC-2ts1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vhd CYTOCHROME C551
PEROXIDASE

(Pseudomonas
aeruginosa) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		3 ARG A  42
PHE A  38
LEU A 311
 None
 0.83A 5x1bC-2vhdA:
undetectable		 5x1bC-2vhdA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xa0 APOPTOSIS REGULATOR
BCL-2

(Homo sapiens) 		PF00452
(Bcl-2)
PF02180
(BH4) 		3 ARG A 164
PHE A 130
LEU A 119
 None
 0.90A 5x1bC-2xa0A:
undetectable		 5x1bC-2xa0A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xpz LEUKOTRIENE A-4
HYDROLASE

(Saccharomyces
cerevisiae) 		PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C) 		3 ARG A 406
PHE A 359
LEU A 414
 None
 0.92A 5x1bC-2xpzA:
undetectable		 5x1bC-2xpzA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asi NEUREXIN-1-ALPHA

(Bos taurus) 		PF02210
(Laminin_G_2) 		3 ARG A1024
PHE A 894
LEU A 989
 None
 0.56A 5x1bC-3asiA:
undetectable		 5x1bC-3asiA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3axy PROTEIN HEADING DATE
3A

(Oryza sativa) 		PF01161
(PBP) 		3 ARG A  26
PHE A 124
LEU A  11
 None
 0.87A 5x1bC-3axyA:
undetectable		 5x1bC-3axyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bks STEROL CARRIER
PROTEIN-2 LIKE-3

(Aedes aegypti) 		PF02036
(SCP2) 		3 ARG A  21
PHE A  26
LEU A  16
 None
None
PLM  A 400 ( 4.3A)
 0.79A 5x1bC-3bksA:
undetectable		 5x1bC-3bksA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csw PUTATIVE
BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Thermotoga
maritima) 		PF01063
(Aminotran_4) 		3 ARG A  85
PHE A  42
LEU A 104
 None
 0.93A 5x1bC-3cswA:
undetectable		 5x1bC-3cswA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ec1 YQEH GTPASE

(Geobacillus
stearothermophilus) 		PF01926
(MMR_HSR1) 		3 ARG A 249
PHE A 260
LEU A 285
 None
 0.91A 5x1bC-3ec1A:
undetectable		 5x1bC-3ec1A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eet PUTATIVE GNTR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
avermitilis) 		PF00392
(GntR)
PF07702
(UTRA) 		3 ARG A 240
PHE A 139
LEU A 207
 None
 0.51A 5x1bC-3eetA:
undetectable		 5x1bC-3eetA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fg4 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN

(Plexaura
homomalla) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 ARG A 861
PHE A 609
LEU A 855
 None
ACY  A2201 (-3.8A)
None
 0.92A 5x1bC-3fg4A:
2.2		 5x1bC-3fg4A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyr PHENOXAZINONE
SYNTHASE

(Streptomyces
antibioticus) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A 615
PHE A 599
LEU A 502
 None
 0.86A 5x1bC-3gyrA:
undetectable		 5x1bC-3gyrA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdj PROBABLE ORNITHINE
CYCLODEAMINASE

(Bordetella
pertussis) 		PF02423
(OCD_Mu_crystall) 		3 ARG A 226
PHE A 205
LEU A 200
 None
 0.91A 5x1bC-3hdjA:
undetectable		 5x1bC-3hdjA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5t AMINOTRANSFERASE

(Rhodobacter
sphaeroides) 		PF00202
(Aminotran_3) 		3 ARG A 179
PHE A 222
LEU A 128
 None
 0.63A 5x1bC-3i5tA:
undetectable		 5x1bC-3i5tA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ils AFLATOXIN
BIOSYNTHESIS
POLYKETIDE SYNTHASE

(Aspergillus
parasiticus) 		PF00975
(Thioesterase) 		3 ARG A2106
PHE A2078
LEU A2103
 None
 0.92A 5x1bC-3ilsA:
undetectable		 5x1bC-3ilsA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mw6 UNCHARACTERIZED
PROTEIN NMB1681

(Neisseria
meningitidis) 		PF04352
(ProQ) 		3 ARG A  87
PHE A  41
LEU A  81
 None
 0.91A 5x1bC-3mw6A:
undetectable		 5x1bC-3mw6A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o57 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ARG A 331
PHE A 216
LEU A 315
 None
 0.65A 5x1bC-3o57A:
undetectable		 5x1bC-3o57A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o5c CYTOCHROME C551
PEROXIDASE

(Shewanella
oneidensis) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		3 ARG A  51
PHE A  47
LEU A 315
 None
 0.93A 5x1bC-3o5cA:
undetectable		 5x1bC-3o5cA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oqp PUTATIVE
ISOCHORISMATASE

(Paraburkholderia
xenovorans) 		PF00857
(Isochorismatase) 		3 ARG A   6
PHE A 138
LEU A 191
 None
 0.70A 5x1bC-3oqpA:
undetectable		 5x1bC-3oqpA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pnn CONSERVED DOMAIN
PROTEIN

(Porphyromonas
gingivalis) 		no annotation 3 ARG A 187
PHE A 194
LEU A 157
 None
 0.91A 5x1bC-3pnnA:
undetectable		 5x1bC-3pnnA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poy NEUREXIN-1-ALPHA

(Bos taurus) 		PF00008
(EGF)
PF02210
(Laminin_G_2) 		3 ARG A1084
PHE A 954
LEU A1049
 None
 0.68A 5x1bC-3poyA:
undetectable		 5x1bC-3poyA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q06 CELLULAR TUMOR
ANTIGEN P53

(Homo sapiens) 		PF00870
(P53)
PF07710
(P53_tetramer) 		3 ARG A 158
PHE A 212
LEU A 206
 None
 0.71A 5x1bC-3q06A:
undetectable		 5x1bC-3q06A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qcw NEUREXIN-1-ALPHA

(Bos taurus) 		PF00008
(EGF)
PF02210
(Laminin_G_2) 		3 ARG A1068
PHE A 938
LEU A1033
 None
 0.66A 5x1bC-3qcwA:
undetectable		 5x1bC-3qcwA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r7k PROBABLE ACYL COA
DEHYDROGENASE

(Mycobacteroides
abscessus) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 ARG A 192
PHE A 234
LEU A 158
 None
 0.86A 5x1bC-3r7kA:
3.5		 5x1bC-3r7kA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rc0 N-LYSINE
METHYLTRANSFERASE
SETD6

(Homo sapiens) 		PF00856
(SET)
PF09273
(Rubis-subs-bind) 		3 ARG A  30
PHE A  90
LEU A  26
 EDO  A 479 (-4.1A)
None
EDO  A 479 ( 4.1A)
 0.92A 5x1bC-3rc0A:
undetectable		 5x1bC-3rc0A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rd5 MYPAA.01249.C

(Mycobacterium
avium) 		PF00106
(adh_short) 		3 ARG A 131
PHE A 246
LEU A 241
 None
 0.93A 5x1bC-3rd5A:
undetectable		 5x1bC-3rd5A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqn CONSERVED DOMAIN
PROTEIN

(Enterococcus
faecalis) 		PF05043
(Mga) 		3 ARG A 215
PHE A 136
LEU A 149
 None
 0.90A 5x1bC-3sqnA:
undetectable		 5x1bC-3sqnA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A

(Bacillus
subtilis) 		PF00580
(UvrD-helicase)
PF12705
(PDDEXK_1)
PF13361
(UvrD_C) 		3 ARG A 926
PHE A 492
LEU A 905
 None
 0.77A 5x1bC-3u44A:
2.1		 5x1bC-3u44A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uko ALCOHOL
DEHYDROGENASE
CLASS-3

(Arabidopsis
thaliana) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 ARG A 221
PHE A 243
LEU A 260
 None
 0.85A 5x1bC-3ukoA:
undetectable		 5x1bC-3ukoA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wad GLYCOSYLTRANSFERASE

(Streptomyces
halstedii) 		PF06722
(DUF1205) 		3 ARG A 247
PHE A 304
LEU A 239
 None
 0.94A 5x1bC-3wadA:
undetectable		 5x1bC-3wadA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aal CYTOCHROME C551
PEROXIDASE

(Geobacter
sulfurreducens) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		3 ARG A  64
PHE A  60
LEU A 333
 None
 0.85A 5x1bC-4aalA:
undetectable		 5x1bC-4aalA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bqh UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE

(Trypanosoma
brucei) 		PF01704
(UDPGP) 		3 ARG A 265
PHE A 362
LEU A 261
 None
 0.88A 5x1bC-4bqhA:
undetectable		 5x1bC-4bqhA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emy AMINOTRANSFERASE
CLASS I AND II

(Anaerococcus
prevotii) 		PF00155
(Aminotran_1_2) 		3 ARG A 385
PHE A 376
LEU A  41
 None
 0.91A 5x1bC-4emyA:
undetectable		 5x1bC-4emyA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4exq UROPORPHYRINOGEN
DECARBOXYLASE

(Burkholderia
thailandensis) 		PF01208
(URO-D) 		3 ARG A 144
PHE A  10
LEU A  65
 None
 0.75A 5x1bC-4exqA:
undetectable		 5x1bC-4exqA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gao DCN1-LIKE PROTEIN 2

(Homo sapiens) 		PF03556
(Cullin_binding) 		3 ARG A 189
PHE A 160
LEU A 148
 None
 0.58A 5x1bC-4gaoA:
undetectable		 5x1bC-4gaoA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j6e UDP-2,3-DIACYLGLUCOS
AMINE
PYROPHOSPHATASE LPXI

(Caulobacter
vibrioides) 		PF06230
(DUF1009) 		3 ARG A 223
PHE A 115
LEU A 108
 None
None
UDG  A 301 (-4.4A)
 0.85A 5x1bC-4j6eA:
undetectable		 5x1bC-4j6eA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jso OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		3 ARG A 484
PHE A 134
LEU A 479
 None
 0.78A 5x1bC-4jsoA:
undetectable		 5x1bC-4jsoA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jz2 SUPEROXIDE DISMUTASE

(Clostridioides
difficile) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		3 ARG A 135
PHE A 140
LEU A 170
 None
 0.94A 5x1bC-4jz2A:
undetectable		 5x1bC-4jz2A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lun NONSENSE-MEDIATED
MRNA DECAY PROTEIN 2

(Saccharomyces
cerevisiae) 		PF02854
(MIF4G) 		3 ARG U 139
PHE U 147
LEU U  81
 None
 0.68A 5x1bC-4lunU:
2.4		 5x1bC-4lunU:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nme PROLINE
DEHYDROGENASE AND
DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE

(Geobacter
sulfurreducens) 		PF00171
(Aldedh)
PF01619
(Pro_dh) 		3 ARG A 568
PHE A 478
LEU A 575
 None
EDO  A1109 (-4.5A)
None
 0.91A 5x1bC-4nmeA:
undetectable		 5x1bC-4nmeA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6m AF2299, A
CDP-ALCOHOL
PHOSPHOTRANSFERASE

(Archaeoglobus
fulgidus) 		PF01066
(CDP-OH_P_transf) 		3 ARG A   2
PHE A  83
LEU A  66
 None
 0.69A 5x1bC-4o6mA:
2.1		 5x1bC-4o6mA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oca UDP-4-AMINO-4-DEOXY-
L-ARABINOSE--OXOGLUT
ARATE
AMINOTRANSFERASE

(Salmonella
enterica) 		PF01041
(DegT_DnrJ_EryC1) 		3 ARG A  15
PHE A 372
LEU A  11
 None
 0.92A 5x1bC-4ocaA:
undetectable		 5x1bC-4ocaA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfw ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		3 ARG A 296
PHE A 508
LEU A 503
 None
 0.84A 5x1bC-4pfwA:
undetectable		 5x1bC-4pfwA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4y COXSACKIEVIRUS
CAPSID PROTEIN VP2
COXSACKIEVIRUS
CAPSID PROTEIN VP3

(Enterovirus C;
Enterovirus C) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 ARG 2 200
PHE 3 117
LEU 3 157
 None
 0.56A 5x1bC-4q4y2:
undetectable		 5x1bC-4q4y2:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q85 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E ACCESSORY FACTOR
YCAO

(Escherichia
coli) 		PF02624
(YcaO) 		3 ARG A 127
PHE A 158
LEU A 121
 None
 0.88A 5x1bC-4q85A:
undetectable		 5x1bC-4q85A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qg5 PUTATIVE
PHOSPHOGLUCOMUTASE

(Leishmania
major) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ARG A 212
PHE A 294
LEU A 433
 None
 0.77A 5x1bC-4qg5A:
undetectable		 5x1bC-4qg5A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r6i ANTHRAX TOXIN
EXPRESSION
TRANS-ACTING
POSITIVE REGULATOR

(Bacillus
anthracis) 		PF00874
(PRD)
PF05043
(Mga)
PF08279
(HTH_11) 		3 ARG A 384
PHE A 350
LEU A 302
 None
 0.95A 5x1bC-4r6iA:
undetectable		 5x1bC-4r6iA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rih GLYCOSYL TRANSFERASE
HOMOLOG,GLYCOSYL
TRANSFERASE

(Streptomyces
fradiae;
Streptomyces
cyanogenus) 		PF06722
(DUF1205) 		3 ARG A  66
PHE A  88
LEU A 152
 None
 0.75A 5x1bC-4rihA:
undetectable		 5x1bC-4rihA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tu3 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 74

(Saccharomyces
cerevisiae) 		PF05719
(GPP34) 		3 ARG A 283
PHE A 296
LEU A 310
 None
 0.90A 5x1bC-4tu3A:
undetectable		 5x1bC-4tu3A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7t DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3A

(Homo sapiens) 		PF00145
(DNA_methylase) 		3 ARG A 488
PHE A 475
LEU A 500
 None
 0.84A 5x1bC-4u7tA:
undetectable		 5x1bC-4u7tA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzj NOTUM

(Drosophila
melanogaster) 		PF03283
(PAE) 		3 ARG A 601
PHE A 333
LEU A 370
 None
 0.94A 5x1bC-4uzjA:
undetectable		 5x1bC-4uzjA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzv HEMOGLOBIN

(Thermobifida
fusca) 		PF01152
(Bac_globin) 		3 ARG A  48
PHE A  53
LEU A 130
 None
 0.88A 5x1bC-4uzvA:
undetectable		 5x1bC-4uzvA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wj3 ASPARTATE--TRNA(ASP/
ASN) LIGASE

(Pseudomonas
aeruginosa) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		3 ARG M 320
PHE M 396
LEU M 295
 None
 0.76A 5x1bC-4wj3M:
undetectable		 5x1bC-4wj3M:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzi CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ARG A 503
PHE A 388
LEU A 487
 IOD  A 805 (-4.3A)
None
None
 0.67A 5x1bC-4wziA:
undetectable		 5x1bC-4wziA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d91 AF2299
PROTEIN,PHOSPHATIDYL
INOSITOL SYNTHASE

(Renibacterium
salmoninarum;
Archaeoglobus
fulgidus) 		PF01066
(CDP-OH_P_transf) 		3 ARG A-129
PHE A -48
LEU A -65
 None
 0.52A 5x1bC-5d91A:
2.4		 5x1bC-5d91A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjv VOLTAGE-DEPENDENT
L-TYPE CALCIUM
CHANNEL SUBUNIT
ALPHA-1S

(Oryctolagus
cuniculus) 		PF00520
(Ion_trans)
PF08763
(Ca_chan_IQ)
PF16905
(GPHH) 		3 ARG A 897
PHE A 843
LEU A 816
 None
 0.93A 5x1bC-5gjvA:
7.6		 5x1bC-5gjvA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hk2 SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1

(Homo sapiens) 		PF04622
(ERG2_Sigma1R) 		3 ARG A  66
PHE A  58
LEU A  79
 None
 0.86A 5x1bC-5hk2A:
undetectable		 5x1bC-5hk2A:
19.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5iy5 CYTOCHROME C OXIDASE
SUBUNIT 3

(Bos taurus) 		PF00510
(COX3) 		3 ARG C 156
PHE C 164
LEU C 223
 CHD  C 307 (-4.0A)
CHD  C 307 (-3.9A)
None
 0.00A 5x1bC-5iy5C:
35.8		 5x1bC-5iy5C:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kju SHIKIMATE
O-HYDROXYCINNAMOYLTR
ANSFERASE

(Arabidopsis
thaliana) 		PF02458
(Transferase) 		3 ARG A 269
PHE A 429
LEU A 366
 None
 0.89A 5x1bC-5kjuA:
undetectable		 5x1bC-5kjuA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m5p PRE-MRNA-SPLICING
HELICASE BRR2

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		3 ARG A1507
PHE A1367
LEU A1359
 None
 0.66A 5x1bC-5m5pA:
undetectable		 5x1bC-5m5pA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o71 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25

(Homo sapiens) 		no annotation 3 ARG A 376
PHE A 372
LEU A 393
 None
 0.52A 5x1bC-5o71A:
1.3		 5x1bC-5o71A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7q RHO-ASSOCIATED
PROTEIN KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		3 ARG A  83
PHE A 410
LEU A  55
 None
 0.94A 5x1bC-5u7qA:
1.9		 5x1bC-5u7qA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ujz HEMAGGLUTININ HA1

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		3 ARG A 262
PHE A 258
LEU A 236
 None
 0.90A 5x1bC-5ujzA:
undetectable		 5x1bC-5ujzA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v88 LYSOZYME,DCN1-LIKE
PROTEIN 1

(Homo sapiens;
Escherichia
virus T4) 		PF00959
(Phage_lysozyme)
PF03556
(Cullin_binding) 		3 ARG A1189
PHE A1160
LEU A1148
 None
 0.45A 5x1bC-5v88A:
undetectable		 5x1bC-5v88A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wrl AP-2 COMPLEX SUBUNIT
MU

(Rattus
norvegicus) 		no annotation 3 ARG A 162
PHE A 407
LEU A 206
 None
 0.47A 5x1bC-5wrlA:
undetectable		 5x1bC-5wrlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxu RIBOSOMAL PROTEIN
US4
RIBOSOMAL PROTEIN
ES30

(Toxoplasma
gondii;
Toxoplasma
gondii) 		PF00163
(Ribosomal_S4)
PF01479
(S4)
PF00467
(KOW)
PF00900
(Ribosomal_S4e)
PF01479
(S4)
PF08071
(RS4NT)
PF16121
(40S_S4_C) 		3 ARG J 126
PHE e  40
LEU J  36
 A  2 475 ( 3.6A)
None
None
 0.93A 5x1bC-5xxuJ:
undetectable		 5x1bC-5xxuJ:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cza -

(-) 		no annotation 3 ARG B 188
PHE B 223
LEU B  56
 SF4  B 301 (-4.6A)
None
SF4  B 302 ( 4.2A)
 0.73A 5x1bC-6czaB:
undetectable		 5x1bC-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6es9 ACYL-COA
DEHYDROGENASE

(Paracoccus
denitrificans) 		no annotation 3 ARG A 333
PHE A 385
LEU A 299
 None
 0.87A 5x1bC-6es9A:
0.0		 5x1bC-6es9A:
undetectable