SIMILAR PATTERNS OF AMINO ACIDS FOR 5WYQ_A_SAMA401_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1geu GLUTATHIONE
REDUCTASE

(Escherichia
coli) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ASP A 158
SER A 157
ASP A 156
HIS A 145
 None
FAD  A 451 ( 3.9A)
None
None
 0.92A 5wyqB-1geuA:
0.5		 5wyqB-1geuA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1now BETA-HEXOSAMINIDASE
BETA CHAIN

(Homo sapiens) 		PF00728
(Glyco_hydro_20)
PF14845
(Glycohydro_20b2) 		4 ASP A 208
SER A 210
ASP A 240
HIS A 294
 None
None
IFG  A 557 ( 4.7A)
IFG  A 557 ( 4.3A)
 1.36A 5wyqB-1nowA:
0.3		 5wyqB-1nowA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sg3 ALLANTOICASE

(Saccharomyces
cerevisiae) 		PF03561
(Allantoicase) 		4 ASP A 212
SER A 211
ASP A 246
HIS A 244
 None
 1.30A 5wyqB-1sg3A:
undetectable		 5wyqB-1sg3A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eb0 MANGANESE-DEPENDENT
INORGANIC
PYROPHOSPHATASE

(Methanocaldococcus
jannaschii) 		PF01368
(DHH)
PF02833
(DHHA2) 		4 ASP A  11
SER A  14
ASP A  13
HIS A  88
 MN  A 501 (-2.5A)
MN  A 501 ( 3.7A)
MN  A 502 (-3.2A)
MN  A 502 (-3.6A)
 1.49A 5wyqB-2eb0A:
1.1		 5wyqB-2eb0A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jax HYPOTHETICAL PROTEIN
TB31.7

(Mycobacterium
tuberculosis) 		PF00582
(Usp) 		4 ASP A  15
SER A 121
ASP A  16
HIS A  67
 ATP  A1296 (-3.2A)
None
None
None
 1.42A 5wyqB-2jaxA:
0.5		 5wyqB-2jaxA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ph5 HOMOSPERMIDINE
SYNTHASE

(Legionella
pneumophila) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		4 ASP A 462
SER A 461
ASP A 459
HIS A 249
 None
 1.41A 5wyqB-2ph5A:
1.2		 5wyqB-2ph5A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qb0 TELSAM DOMAIN -
LYSOZYME CHIMERA

(Escherichia
virus T4) 		PF00959
(Phage_lysozyme)
PF02198
(SAM_PNT) 		4 ASP B  32
SER B  30
ASP B  33
HIS B  21
 None
None
MN  B 257 (-2.6A)
MN  B 257 (-3.3A)
 1.31A 5wyqB-2qb0B:
0.0		 5wyqB-2qb0B:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qb6 EXOPOLYPHOSPHATASE

(Saccharomyces
cerevisiae) 		PF01368
(DHH)
PF02833
(DHHA2) 		4 ASP A  39
SER A  42
ASP A  41
HIS A 148
 MN  A 401 ( 4.7A)
None
MN  A 401 (-3.1A)
MN  A 401 ( 3.3A)
 1.48A 5wyqB-2qb6A:
0.9		 5wyqB-2qb6A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vob TRYPANOTHIONE
SYNTHETASE

(Leishmania
major) 		PF03738
(GSP_synth)
PF05257
(CHAP) 		4 ASP A 447
SER A 446
ASP A 445
HIS A 399
 None
 0.90A 5wyqB-2vobA:
0.0		 5wyqB-2vobA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ya1 PUTATIVE ALKALINE
AMYLOPULLULANASE

(Streptococcus
pneumoniae) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48)
PF03714
(PUD) 		4 ASP A 995
SER A 600
ASP A 597
HIS A 594
 None
 1.48A 5wyqB-2ya1A:
undetectable		 5wyqB-2ya1A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ya2 PUTATIVE ALKALINE
AMYLOPULLULANASE

(Streptococcus
pneumoniae) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		4 ASP A 540
SER A 145
ASP A 142
HIS A 139
 None
 1.45A 5wyqB-2ya2A:
0.3		 5wyqB-2ya2A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yb4 AMIDOHYDROLASE

(Chromobacterium
violaceum) 		PF02811
(PHP) 		4 ASP A  38
SER A  13
ASP A  14
HIS A 250
 None
 1.43A 5wyqB-2yb4A:
undetectable		 5wyqB-2yb4A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aka PUTATIVE CALCIUM
BINDING PROTEIN

(Streptomyces
coelicolor) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		4 ASP A  29
SER A  28
ASP A  26
HIS A  24
 CA  A 171 (-2.2A)
None
None
None
 1.47A 5wyqB-3akaA:
undetectable		 5wyqB-3akaA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3auo DNA POLYMERASE BETA
FAMILY (X FAMILY)

(Thermus
thermophilus) 		PF14520
(HHH_5)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb) 		4 ASP A 373
SER A 348
ASP A 349
HIS A 531
 None
 1.33A 5wyqB-3auoA:
undetectable		 5wyqB-3auoA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ipo PUTATIVE THIOSULFATE
SULFURTRANSFERASE
YNJE

(Escherichia
coli) 		PF00581
(Rhodanese) 		4 ASP A 364
SER A 362
ASP A 365
HIS A  91
 None
 1.39A 5wyqB-3ipoA:
0.8		 5wyqB-3ipoA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jyf 2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
BIFUNCTIONAL
PERIPLASMIC PROTEIN

(Klebsiella
pneumoniae) 		PF00149
(Metallophos) 		4 ASP A 151
SER A 150
ASP A 149
HIS A 155
 None
 1.09A 5wyqB-3jyfA:
undetectable		 5wyqB-3jyfA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE

(Vibrio
vulnificus) 		PF02784
(Orn_Arg_deC_N) 		4 ASP A 514
SER A 513
ASP A 512
HIS A 559
 None
AG2  A1002 (-3.1A)
AG2  A1002 (-3.2A)
None
 1.32A 5wyqB-3n2oA:
1.3		 5wyqB-3n2oA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps9 TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC

(Escherichia
coli) 		PF01266
(DAO)
PF05430
(Methyltransf_30) 		4 ASP A 533
SER A 531
ASP A 534
HIS A 522
 None
 1.32A 5wyqB-3ps9A:
undetectable		 5wyqB-3ps9A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfz APOPTOTIC PEPTIDASE
ACTIVATING FACTOR 1

(Mus musculus) 		PF00400
(WD40)
PF00931
(NB-ARC)
PF12894
(ANAPC4_WD40) 		4 ASP A 754
SER A 752
ASP A 755
HIS A 713
 None
 1.39A 5wyqB-3sfzA:
undetectable		 5wyqB-3sfzA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h7u PYRANOSE
DEHYDROGENASE

(Leucoagaricus
meleagris) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 ASP A 114
SER A 112
ASP A 115
HIS A 551
 None
 1.39A 5wyqB-4h7uA:
undetectable		 5wyqB-4h7uA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hb5 ENGINEERED PROTEIN

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A  69
SER A  68
ASP A  67
HIS A  42
 None
 1.32A 5wyqB-4hb5A:
undetectable		 5wyqB-4hb5A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hb5 ENGINEERED PROTEIN

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A 102
SER A 101
ASP A 100
HIS A  75
 None
 1.33A 5wyqB-4hb5A:
undetectable		 5wyqB-4hb5A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hb5 ENGINEERED PROTEIN

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A 135
SER A 134
ASP A 133
HIS A 108
 None
 1.32A 5wyqB-4hb5A:
undetectable		 5wyqB-4hb5A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL

(Moraxella
catarrhalis) 		PF13360
(PQQ_2) 		4 ASP A 305
SER A 303
ASP A 307
HIS A 323
 None
 1.44A 5wyqB-4immA:
undetectable		 5wyqB-4immA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru5 TAILSPIKE GP27

(Pseudomonas
phage phi297) 		no annotation 4 ASP A 380
SER A 353
ASP A 239
HIS A 214
 None
 1.19A 5wyqB-4ru5A:
undetectable		 5wyqB-4ru5A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wk7 A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 4

(Homo sapiens) 		PF01421
(Reprolysin) 		4 ASP A 351
SER A 355
ASP A 350
HIS A 234
 None
 1.28A 5wyqB-4wk7A:
undetectable		 5wyqB-4wk7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4woj ASPARTATE
SEMIALDEHYDE
DEHYDROGENASE

(Francisella
tularensis) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ASP A 104
SER A 107
ASP A 129
HIS A  82
 None
 1.20A 5wyqB-4wojA:
undetectable		 5wyqB-4wojA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4woj ASPARTATE
SEMIALDEHYDE
DEHYDROGENASE

(Francisella
tularensis) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ASP A 106
SER A 107
ASP A 129
HIS A  82
 None
 0.94A 5wyqB-4wojA:
undetectable		 5wyqB-4wojA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d68 KREV INTERACTION
TRAPPED PROTEIN 1

(Homo sapiens) 		PF00373
(FERM_M)
PF13857
(Ank_5) 		4 ASP A 320
SER A 319
ASP A 318
HIS A 293
 None
 1.31A 5wyqB-5d68A:
1.8		 5wyqB-5d68A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eb5 HNL ISOENZYME 5

(Prunus dulcis) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 ASP A 240
SER A 239
ASP A 238
HIS A 244
 None
 1.05A 5wyqB-5eb5A:
undetectable		 5wyqB-5eb5A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eil TRI-05

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A  68
SER A  67
ASP A  66
HIS A  41
 None
 1.33A 5wyqB-5eilA:
undetectable		 5wyqB-5eilA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eil TRI-05

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A 134
SER A 133
ASP A 132
HIS A 107
 None
 1.37A 5wyqB-5eilA:
undetectable		 5wyqB-5eilA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h76 DARPIN,IMMUNOGLOBULI
N G-BINDING PROTEIN
A

(Staphylococcus
aureus;
synthetic
construct) 		PF02216
(B)
PF12796
(Ank_2) 		4 ASP A 112
SER A 111
ASP A 110
HIS A  85
 None
 1.46A 5wyqB-5h76A:
undetectable		 5wyqB-5h76A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hs0 ANKYRIN DOMAIN
PROTEIN ANK1C4_7

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A  69
SER A  68
ASP A  67
HIS A  42
 None
 1.41A 5wyqB-5hs0A:
undetectable		 5wyqB-5hs0A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hs0 ANKYRIN DOMAIN
PROTEIN ANK1C4_7

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A  69
SER A  68
ASP A  67
HIS A  76
 None
 0.99A 5wyqB-5hs0A:
undetectable		 5wyqB-5hs0A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hs0 ANKYRIN DOMAIN
PROTEIN ANK1C4_7

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A 102
SER A 101
ASP A 100
HIS A  75
 None
 1.38A 5wyqB-5hs0A:
undetectable		 5wyqB-5hs0A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hs0 ANKYRIN DOMAIN
PROTEIN ANK1C4_7

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A 102
SER A 101
ASP A 100
HIS A 109
 None
 1.10A 5wyqB-5hs0A:
undetectable		 5wyqB-5hs0A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hs0 ANKYRIN DOMAIN
PROTEIN ANK1C4_7

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A 135
SER A 134
ASP A 133
HIS A 108
 None
 1.42A 5wyqB-5hs0A:
undetectable		 5wyqB-5hs0A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kba DESIGNED PROTEIN
ANK1C2

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A  35
SER A  34
ASP A  33
HIS A  42
 None
 1.14A 5wyqB-5kbaA:
undetectable		 5wyqB-5kbaA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kba DESIGNED PROTEIN
ANK1C2

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A  68
SER A  67
ASP A  66
HIS A  41
 None
 1.34A 5wyqB-5kbaA:
undetectable		 5wyqB-5kbaA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kba DESIGNED PROTEIN
ANK1C2

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A  68
SER A  67
ASP A  66
HIS A  75
 None
 1.04A 5wyqB-5kbaA:
undetectable		 5wyqB-5kbaA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kba DESIGNED PROTEIN
ANK1C2

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A 101
SER A 100
ASP A  99
HIS A  74
 None
 1.37A 5wyqB-5kbaA:
undetectable		 5wyqB-5kbaA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kba DESIGNED PROTEIN
ANK1C2

(synthetic
construct) 		PF12796
(Ank_2) 		4 ASP A 101
SER A 100
ASP A  99
HIS A 108
 None
 1.03A 5wyqB-5kbaA:
undetectable		 5wyqB-5kbaA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kwd ANKYRIN
REPEAT-CONTAINING
PROTEIN

(Metallosphaera
yellowstonensis) 		PF12796
(Ank_2) 		4 ASP A  68
SER A  67
ASP A  66
HIS A  41
 None
 1.31A 5wyqB-5kwdA:
undetectable		 5wyqB-5kwdA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kwd ANKYRIN
REPEAT-CONTAINING
PROTEIN

(Metallosphaera
yellowstonensis) 		PF12796
(Ank_2) 		4 ASP A 101
SER A 100
ASP A  99
HIS A  74
 None
 1.32A 5wyqB-5kwdA:
undetectable		 5wyqB-5kwdA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kwd ANKYRIN
REPEAT-CONTAINING
PROTEIN

(Metallosphaera
yellowstonensis) 		PF12796
(Ank_2) 		4 ASP A 134
SER A 133
ASP A 132
HIS A 107
 None
 1.36A 5wyqB-5kwdA:
undetectable		 5wyqB-5kwdA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l0p TRANSCRIPTION FACTOR
ETV6, TRANSCRIPTION
FACTOR ETV6,
TRANSCRIPTION FACTOR
ETV6, FERRIC UPTAKE
REGULATION PROTEIN
CHIMERA

(Klebsiella
pneumoniae;
Homo sapiens) 		PF01475
(FUR)
PF02198
(SAM_PNT) 		4 ASP A  28
SER A  26
ASP A  29
HIS A  17
 None
 1.41A 5wyqB-5l0pA:
undetectable		 5wyqB-5l0pA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mch CELLOBIOHYDROLASE
CHBI

(Daphnia pulex) 		PF00840
(Glyco_hydro_7) 		4 ASP A 274
SER A 272
ASP A 269
HIS A 202
 None
 1.39A 5wyqB-5mchA:
undetectable		 5wyqB-5mchA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wyr TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE

(Pseudomonas
aeruginosa) 		no annotation 4 ASP A 174
SER A 175
ASP A 182
HIS A 185
 None
 0.82A 5wyqB-5wyrA:
31.4		 5wyqB-5wyrA:
undetectable