SIMILAR PATTERNS OF AMINO ACIDS FOR 5WBV_B_SAMB402_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ac5 | KEX1(DELTA)P (Saccharomycescerevisiae) |
PF00450(Peptidase_S10) | 3 | HIS A 448GLU A 88ASN A 74 | None | 0.92A | 5wbvB-1ac5A:0.0 | 5wbvB-1ac5A:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1axn | ANNEXIN III (Homo sapiens) |
PF00191(Annexin) | 3 | HIS A 295GLU A 257ASN A 246 | None | 0.84A | 5wbvB-1axnA:0.0 | 5wbvB-1axnA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gco | GLUCOSEDEHYDROGENASE (Bacillusmegaterium) |
PF13561(adh_short_C2) | 3 | HIS A 147GLU A 96ASN A 196 | NoneNoneNAD A 601 (-3.9A) | 0.99A | 5wbvB-1gcoA:0.0 | 5wbvB-1gcoA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gxs | P-(S)-HYDROXYMANDELONITRILE LYASE CHAINAP-(S)-HYDROXYMANDELONITRILE LYASE CHAINB (Sorghumbicolor;Sorghum bicolor) |
PF00450(Peptidase_S10)PF00450(Peptidase_S10) | 3 | HIS B 414GLU A 76ASN A 61 | DKA A 701 (-4.0A)NoneDKA A 701 (-3.8A) | 0.96A | 5wbvB-1gxsB:0.0 | 5wbvB-1gxsB:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iqo | HYPOTHETICAL PROTEINMTH1880 (Methanothermobacter) |
PF05370(DUF749) | 3 | HIS A 87GLU A 39ASN A 60 | None | 0.98A | 5wbvB-1iqoA:undetectable | 5wbvB-1iqoA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k77 | HYPOTHETICAL PROTEINYGBM (Escherichiacoli) |
PF01261(AP_endonuc_2) | 3 | HIS A 202GLU A 143ASN A 60 | None MG A 300 ( 2.7A)None | 0.79A | 5wbvB-1k77A:undetectable | 5wbvB-1k77A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofm | CHONDROITINASE B (Pedobacterheparinus) |
PF14592(Chondroitinas_B) | 3 | HIS A 272GLU A 245ASN A 213 | NoneASG A 608 (-3.7A)None | 0.94A | 5wbvB-1ofmA:0.0 | 5wbvB-1ofmA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q47 | SEMAPHORIN 3A (Mus musculus) |
PF01403(Sema) | 3 | HIS A 515GLU A 478ASN A 44 | None | 0.92A | 5wbvB-1q47A:0.0 | 5wbvB-1q47A:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rtw | TRANSCRIPTIONALACTIVATOR, PUTATIVE (Pyrococcusfuriosus) |
PF03070(TENA_THI-4) | 3 | HIS A 20GLU A 25ASN A 35 | None | 1.02A | 5wbvB-1rtwA:0.0 | 5wbvB-1rtwA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tuu | ACETATE KINASE (Methanosarcinathermophila) |
PF00871(Acetate_kinase) | 3 | HIS A 180GLU A 384ASN A 7 | SO4 A 400 (-3.9A)NoneNone | 0.90A | 5wbvB-1tuuA:undetectable | 5wbvB-1tuuA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ujn | DEHYDROQUINATESYNTHASE (Thermusthermophilus) |
PF01761(DHQ_synthase) | 3 | HIS A 243GLU A 62ASN A 141 | None | 0.86A | 5wbvB-1ujnA:undetectable | 5wbvB-1ujnA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ujn | DEHYDROQUINATESYNTHASE (Thermusthermophilus) |
PF01761(DHQ_synthase) | 3 | HIS A 247GLU A 62ASN A 141 | None | 0.75A | 5wbvB-1ujnA:undetectable | 5wbvB-1ujnA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vgq | FORMYL-COENZYME ATRANSFERASE (Oxalobacterformigenes) |
PF02515(CoA_transf_3) | 3 | HIS A 404GLU A 411ASN A 32 | None | 0.95A | 5wbvB-1vgqA:undetectable | 5wbvB-1vgqA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vsg | VARIANT SURFACEGLYCOPROTEIN MITAT1.2 (Trypanosomabrucei) |
PF00913(Trypan_glycop) | 3 | HIS A 71GLU A 313ASN A 306 | NoneNAG A 366 (-3.5A)None | 0.92A | 5wbvB-1vsgA:undetectable | 5wbvB-1vsgA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wyt | GLYCINEDEHYDROGENASE(DECARBOXYLATING)SUBUNIT 1GLYCINEDEHYDROGENASESUBUNIT 2(P-PROTEIN) (Thermusthermophilus;Thermusthermophilus) |
PF02347(GDC-P)PF02347(GDC-P) | 3 | HIS B 166GLU B 136ASN A 318 | None | 0.78A | 5wbvB-1wytB:undetectable | 5wbvB-1wytB:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a5v | CARBONIC ANHYDRASE(CARBONATEDEHYDRATASE)(CARBONICDEHYDRATASE) (Mycobacteriumtuberculosis) |
PF00484(Pro_CA) | 3 | HIS A 104GLU A 153ASN A 111 | ZN A 401 ( 3.3A)NoneNone | 0.96A | 5wbvB-2a5vA:undetectable | 5wbvB-2a5vA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3a | GLUTAMINE SYNTHETASE (Zea mays) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 3 | HIS A 249GLU A 192ASN A 244 | MN A1002 ( 3.5A) MN A1003 ( 3.0A)P3S A5001 ( 4.7A) | 1.01A | 5wbvB-2d3aA:undetectable | 5wbvB-2d3aA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eql | HORSE MILK LYSOZYME (Equus caballus) |
PF00062(Lys) | 3 | HIS A 114GLU A 33ASN A 37 | None | 1.00A | 5wbvB-2eqlA:undetectable | 5wbvB-2eqlA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fl3 | R.HINP1I RESTRICTIONENDONUCLEASE (Haemophilusinfluenzae) |
PF11463(R-HINP1I) | 3 | HIS A 118GLU A 145ASN A 111 | None | 0.92A | 5wbvB-2fl3A:undetectable | 5wbvB-2fl3A:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kld | POLYCYSTIN-2 (Homo sapiens) |
no annotation | 3 | HIS A 775GLU A 774ASN A 737 | None | 1.00A | 5wbvB-2kldA:undetectable | 5wbvB-2kldA:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjj | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Novosphingobiumaromaticivorans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | HIS A 343GLU A 169ASN A 37 | None | 0.98A | 5wbvB-2qjjA:undetectable | 5wbvB-2qjjA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rjt | BETA-KETOACYL-ACPSYNTHASE II (Streptococcuspneumoniae) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 3 | HIS A 337GLU A 346ASN A 168 | None | 0.98A | 5wbvB-2rjtA:undetectable | 5wbvB-2rjtA:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uu7 | GLUTAMINE SYNTHETASE (Canis lupus) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 3 | HIS A 253GLU A 196ASN A 248 | None MG A 401 (-3.2A)None | 0.93A | 5wbvB-2uu7A:undetectable | 5wbvB-2uu7A:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w48 | SORBITOL OPERONREGULATOR (Klebsiellapneumoniae) |
PF04198(Sugar-bind)PF13936(HTH_38) | 3 | HIS A 98GLU A 66ASN A 60 | None | 0.73A | 5wbvB-2w48A:undetectable | 5wbvB-2w48A:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wvl | MANNOSYL-3-PHOSPHOGLYCERATE SYNTHASE (Thermusthermophilus) |
PF09488(Osmo_MPGsynth) | 3 | HIS A 115GLU A 96ASN A 63 | None | 1.00A | 5wbvB-2wvlA:undetectable | 5wbvB-2wvlA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x05 | EXO-BETA-D-GLUCOSAMINIDASE (Amycolatopsisorientalis) |
PF00703(Glyco_hydro_2)PF02837(Glyco_hydro_2_N) | 3 | HIS A 682GLU A 623ASN A 763 | None | 0.96A | 5wbvB-2x05A:undetectable | 5wbvB-2x05A:12.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xh1 | KYNURENINE/ALPHA-AMINOADIPATEAMINOTRANSFERASE,MITOCHONDRIAL (Homo sapiens) |
PF00155(Aminotran_1_2) | 3 | HIS A 95GLU A 229ASN A 199 | None | 0.93A | 5wbvB-2xh1A:undetectable | 5wbvB-2xh1A:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yqh | UDP-N-ACETYLGLUCOSAMINEPYROPHOSPHORYLASE (Candidaalbicans) |
PF01704(UDPGP) | 3 | HIS A 363GLU A 391ASN A 227 | NoneNoneGN1 A1001 (-3.1A) | 0.94A | 5wbvB-2yqhA:undetectable | 5wbvB-2yqhA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z00 | DIHYDROOROTASE (Thermusthermophilus) |
PF01979(Amidohydro_1) | 3 | HIS A 310GLU A 63ASN A 89 | None | 1.02A | 5wbvB-2z00A:undetectable | 5wbvB-2z00A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zu8 | MANNOSYL-3-PHOSPHOGLYCERATE SYNTHASE (Pyrococcushorikoshii) |
PF09488(Osmo_MPGsynth) | 3 | HIS A 116GLU A 97ASN A 61 | None | 0.96A | 5wbvB-2zu8A:undetectable | 5wbvB-2zu8A:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aux | DNA DOUBLE-STRANDBREAK REPAIR RAD50ATPASE (Methanocaldococcusjannaschii) |
PF13476(AAA_23) | 3 | HIS A 979GLU A 947ASN A 34 | NoneNoneADP A1006 ( 4.8A) | 1.02A | 5wbvB-3auxA:undetectable | 5wbvB-3auxA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c49 | POLY(ADP-RIBOSE)POLYMERASE 3 (Homo sapiens) |
PF00644(PARP)PF02877(PARP_reg) | 3 | HIS A 434GLU A 530ASN A 195 | None | 0.94A | 5wbvB-3c49A:undetectable | 5wbvB-3c49A:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3clh | 3-DEHYDROQUINATESYNTHASE (Helicobacterpylori) |
PF01761(DHQ_synthase) | 3 | HIS A 248GLU A 63ASN A 142 | ZN A 344 (-2.9A)NAD A 400 (-2.7A)NAD A 400 (-3.0A) | 0.75A | 5wbvB-3clhA:undetectable | 5wbvB-3clhA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cne | PUTATIVE PROTEASE I (Bacteroidesthetaiotaomicron) |
PF01965(DJ-1_PfpI) | 3 | HIS A 131GLU A 160ASN A 46 | None | 1.01A | 5wbvB-3cneA:undetectable | 5wbvB-3cneA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fn9 | PUTATIVEBETA-GALACTOSIDASE (Bacteroidesfragilis) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 3 | HIS A 324GLU A 503ASN A 418 | None | 0.95A | 5wbvB-3fn9A:undetectable | 5wbvB-3fn9A:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ga3 | INTERFERON-INDUCEDHELICASE CDOMAIN-CONTAININGPROTEIN 1, MDA5 (Homo sapiens) |
PF11648(RIG-I_C-RD) | 3 | HIS A1021GLU A1017ASN A1012 | None | 1.02A | 5wbvB-3ga3A:undetectable | 5wbvB-3ga3A:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iie | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Yersiniapseudotuberculosis) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 3 | HIS A 153GLU A 152ASN A 227 | None MG A 501 (-2.4A) MG A 501 ( 4.1A) | 0.88A | 5wbvB-3iieA:2.4 | 5wbvB-3iieA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l5a | NADH/FLAVINOXIDOREDUCTASE/NADHOXIDASE (Staphylococcusaureus) |
PF00724(Oxidored_FMN) | 3 | HIS A 191GLU A 206ASN A 146 | None | 0.64A | 5wbvB-3l5aA:undetectable | 5wbvB-3l5aA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lg5 | EPI-ISOZIZAENESYNTHASE (Streptomycescoelicolor) |
no annotation | 3 | HIS A 264GLU A 189ASN A 178 | None | 0.92A | 5wbvB-3lg5A:0.6 | 5wbvB-3lg5A:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mti | RRNA METHYLASE (Streptococcusthermophilus) |
PF06962(rRNA_methylase) | 3 | HIS A 109GLU A 113ASN A 78 | None | 0.95A | 5wbvB-3mtiA:undetectable | 5wbvB-3mtiA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mx8 | RIBONUCLEASEPANCREATIC, LINKER,RIBONUCLEASEPANCREATIC (Bos taurus) |
PF00074(RnaseA) | 3 | HIS A 176GLU A 177ASN A 231 | None | 1.01A | 5wbvB-3mx8A:undetectable | 5wbvB-3mx8A:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ng0 | GLUTAMINE SYNTHETASE (Synechocystissp. PCC 6803) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 3 | HIS A 272GLU A 215ASN A 267 | MN A 477 (-3.2A) MN A 475 (-3.1A)None | 0.93A | 5wbvB-3ng0A:undetectable | 5wbvB-3ng0A:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ngf | AP ENDONUCLEASE,FAMILY 2 (Brucellaabortus) |
PF01261(AP_endonuc_2) | 3 | HIS A 201GLU A 142ASN A 60 | None MN A 262 (-2.6A)None | 0.91A | 5wbvB-3ngfA:undetectable | 5wbvB-3ngfA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3no4 | CREATININEAMIDOHYDROLASE (Nostocpunctiforme) |
PF02633(Creatininase) | 3 | HIS A 4GLU A 45ASN A 64 | None | 0.89A | 5wbvB-3no4A:undetectable | 5wbvB-3no4A:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8l | 6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE (Oryctolaguscuniculus) |
PF00365(PFK) | 3 | HIS A 734GLU A 597ASN A 628 | None | 0.99A | 5wbvB-3o8lA:undetectable | 5wbvB-3o8lA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3okf | 3-DEHYDROQUINATESYNTHASE (Vibrio cholerae) |
PF01761(DHQ_synthase) | 3 | HIS A 268GLU A 77ASN A 156 | NoneNAD A 367 (-3.0A)NAD A 367 ( 3.5A) | 0.52A | 5wbvB-3okfA:undetectable | 5wbvB-3okfA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p1u | SUSD HOMOLOG (Parabacteroidesdistasonis) |
PF12741(SusD-like) | 3 | HIS A 383GLU A 380ASN A 250 | None | 0.99A | 5wbvB-3p1uA:undetectable | 5wbvB-3p1uA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qki | GLUCOSE-6-PHOSPHATEISOMERASE (Plasmodiumfalciparum) |
PF00342(PGI) | 3 | HIS A 122GLU A 103ASN A 320 | None | 0.91A | 5wbvB-3qkiA:3.0 | 5wbvB-3qkiA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qki | GLUCOSE-6-PHOSPHATEISOMERASE (Plasmodiumfalciparum) |
PF00342(PGI) | 3 | HIS A 122GLU A 119ASN A 106 | None | 0.74A | 5wbvB-3qkiA:3.0 | 5wbvB-3qkiA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thu | MANDELATE RACEMASE /MUCONATE LACTONIZINGENZYME FAMILYPROTEIN (Sphingomonassp. SKA58) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | HIS A 344GLU A 170ASN A 38 | NoneNoneGOL A 406 (-3.7A) | 0.99A | 5wbvB-3thuA:undetectable | 5wbvB-3thuA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u0f | BETA-KETOACYLSYNTHASE (Brucellaabortus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 3 | HIS A 333GLU A 342ASN A 165 | None NA A 410 (-3.1A)None | 0.94A | 5wbvB-3u0fA:undetectable | 5wbvB-3u0fA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3usc | HYDROGENASE-1 LARGECHAIN (Escherichiacoli) |
PF00374(NiFeSe_Hases) | 3 | HIS L 351GLU L 549ASN L 45 | None | 1.01A | 5wbvB-3uscL:undetectable | 5wbvB-3uscL:17.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vcn | MANNONATEDEHYDRATASE (Caulobactervibrioides) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | HIS A 344GLU A 170ASN A 38 | NoneNoneGOL A 502 (-3.8A) | 0.95A | 5wbvB-3vcnA:undetectable | 5wbvB-3vcnA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vrb | FLAVOPROTEIN SUBUNITOF COMPLEX IIIRON-SULFUR SUBUNITOF SUCCINATEDEHYDROGENASE (Ascaris suum;Ascaris suum) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C)PF13085(Fer2_3)PF13534(Fer4_17) | 3 | HIS A 250GLU A 545ASN B 77 | None | 0.93A | 5wbvB-3vrbA:undetectable | 5wbvB-3vrbA:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w57 | C2 DOMAIN PROTEIN (Scophthalmusmaximus) |
PF00168(C2) | 3 | HIS A 87GLU A 55ASN A 52 | None | 0.99A | 5wbvB-3w57A:undetectable | 5wbvB-3w57A:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wfa | ALPHA-GLUCOSIDASE (Bacteroidesthetaiotaomicron) |
PF10566(Glyco_hydro_97)PF14508(GH97_N)PF14509(GH97_C) | 3 | HIS A 255GLU A 245ASN A 487 | None | 0.99A | 5wbvB-3wfaA:undetectable | 5wbvB-3wfaA:17.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4au7 | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H2 (Mus musculus) |
PF00856(SET) | 3 | HIS A 32GLU A 117ASN A 182 | SAH A1247 (-3.6A)SAH A1247 (-2.8A)SAH A1247 (-3.1A) | 0.35A | 5wbvB-4au7A:32.3 | 5wbvB-4au7A:60.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4az3 | LYSOSOMAL PROTECTIVEPROTEIN 32 KDA CHAINLYSOSOMAL PROTECTIVEPROTEIN 20 KDA CHAIN (Homo sapiens;Homo sapiens) |
PF00450(Peptidase_S10)PF00450(Peptidase_S10) | 3 | HIS B 429GLU A 69ASN A 55 | S35 A1259 ( 3.9A)NoneS35 A1259 ( 3.7A) | 0.97A | 5wbvB-4az3B:undetectable | 5wbvB-4az3B:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bax | GLUTAMINE SYNTHETASE (Streptomycescoelicolor) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 3 | HIS A 237GLU A 180ASN A 232 | None | 0.87A | 5wbvB-4baxA:undetectable | 5wbvB-4baxA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4be3 | ALGINATE LYASE,FAMILY PL7 (Zobelliagalactanivorans) |
PF08787(Alginate_lyase2) | 3 | HIS A 149GLU A 179ASN A 186 | SRT A 400 (-3.4A)NoneNone | 1.02A | 5wbvB-4be3A:undetectable | 5wbvB-4be3A:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c6s | PROBABLE WRKYTRANSCRIPTION FACTOR52 (Arabidopsisthaliana) |
no annotation | 3 | HIS A 146GLU A 9ASN A 91 | None | 0.91A | 5wbvB-4c6sA:undetectable | 5wbvB-4c6sA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ce4 | MRPL22MRPL39 (Sus scrofa;Sus scrofa) |
PF00237(Ribosomal_L22)no annotation | 3 | HIS c 91GLU W 133ASN W 131 | None | 0.92A | 5wbvB-4ce4c:undetectable | 5wbvB-4ce4c:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cem | REGULATOR OFNONSENSE TRANSCRIPTS2 (Homo sapiens) |
PF02854(MIF4G) | 3 | HIS A 314GLU A 271ASN A 220 | None | 0.98A | 5wbvB-4cemA:undetectable | 5wbvB-4cemA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fi4 | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Caulobacter sp.K31) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | HIS A 344GLU A 170ASN A 38 | NoneNoneGOL A 502 (-3.8A) | 0.97A | 5wbvB-4fi4A:undetectable | 5wbvB-4fi4A:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4it1 | PUTATIVE GLUCARATEDEHYDRATASE (Pseudomonasfluorescens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | HIS A 320GLU A 246ASN A 223 | None MG A 501 (-2.8A)TLA A 502 (-3.7A) | 0.97A | 5wbvB-4it1A:undetectable | 5wbvB-4it1A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jhz | BETA-GLUCURONIDASE (Escherichiacoli) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 3 | HIS A 296GLU A 504ASN A 412 | None | 0.99A | 5wbvB-4jhzA:undetectable | 5wbvB-4jhzA:17.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jkl | BETA-GLUCURONIDASE (Streptococcusagalactiae) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 3 | HIS A 295GLU A 501ASN A 407 | None | 0.99A | 5wbvB-4jklA:undetectable | 5wbvB-4jklA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lnf | GLUTAMINE SYNTHETASE (Bacillussubtilis) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 3 | HIS A 245GLU A 189ASN A 240 | PO4 A 504 ( 3.1A)GLN A 503 ( 2.7A)GLN A 503 (-4.6A) | 0.98A | 5wbvB-4lnfA:undetectable | 5wbvB-4lnfA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n0r | PUTATIVE GLYCOSIDEHYDROLASE (Bacteroidesvulgatus) |
PF13204(DUF4038)PF16586(DUF5060) | 3 | HIS A 303GLU A 228ASN A 223 | None | 0.80A | 5wbvB-4n0rA:undetectable | 5wbvB-4n0rA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nov | XYLOSIDASE/ARABINOFURANOSIDASE XSA43E (Butyrivibrioproteoclasticus) |
PF04616(Glyco_hydro_43) | 3 | HIS A 258GLU A 227ASN A 158 | CA A 401 (-3.7A)NoneNone | 0.83A | 5wbvB-4novA:undetectable | 5wbvB-4novA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uwa | RYANODINE RECEPTOR 1 (Oryctolaguscuniculus) |
PF00622(SPRY)PF01365(RYDR_ITPR)PF02026(RyR)PF02815(MIR)PF08709(Ins145_P3_rec) | 3 | HIS A 255GLU A 397ASN A 473 | None | 0.90A | 5wbvB-4uwaA:undetectable | 5wbvB-4uwaA:5.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xjx | HSDR (Escherichiacoli) |
PF04313(HSDR_N)PF04851(ResIII)PF12008(EcoR124_C) | 3 | HIS A 181GLU A 186ASN A 214 | None | 1.01A | 5wbvB-4xjxA:undetectable | 5wbvB-4xjxA:13.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwi | 3-DEOXY-MANNO-OCTULOSONATECYTIDYLYLTRANSFERASE (Pseudomonasaeruginosa) |
PF02348(CTP_transf_3) | 3 | HIS A 134GLU A 131ASN A 234 | None | 1.00A | 5wbvB-4xwiA:undetectable | 5wbvB-4xwiA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5brr | TISSUE-TYPEPLASMINOGENACTIVATOR (Homo sapiens) |
PF00089(Trypsin) | 3 | HIS E 144GLU E 145ASN E 186 | PGE E 305 (-4.3A)NoneNone | 0.96A | 5wbvB-5brrE:undetectable | 5wbvB-5brrE:19.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5cpr | HISTONE-LYSINEN-METHYLTRANSFERASESUV420H1 (Homo sapiens) |
PF00856(SET) | 3 | HIS B 98GLU B 206ASN B 272 | SAM B 402 (-3.7A)SAM B 402 (-2.9A)SAM B 402 (-3.1A) | 0.22A | 5wbvB-5cprB:35.5 | 5wbvB-5cprB:97.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dny | DNA DOUBLE-STRANDBREAK REPAIR PROTEINMRE11 (Methanocaldococcusjannaschii) |
PF00149(Metallophos) | 3 | HIS A 0GLU A 118ASN A 232 | None | 0.73A | 5wbvB-5dnyA:undetectable | 5wbvB-5dnyA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e2e | BETA-LACTAMASE (Yersiniaenterocolitica) |
PF13354(Beta-lactamase2) | 3 | HIS A 71GLU A 98ASN A 89 | None | 1.02A | 5wbvB-5e2eA:undetectable | 5wbvB-5e2eA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eks | 3-DEHYDROQUINATESYNTHASE (Acinetobacterbaumannii) |
PF01761(DHQ_synthase) | 3 | HIS A 263GLU A 72ASN A 151 | MG A 401 (-3.3A)NAD A 400 (-3.0A)NAD A 400 (-3.4A) | 0.56A | 5wbvB-5eksA:undetectable | 5wbvB-5eksA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f05 | PHI CLASSGLUTATHIONETRANSFERASE GSTF5 (Populustrichocarpa) |
PF00043(GST_C)PF02798(GST_N) | 3 | HIS A 46GLU A 40ASN A 33 | None | 1.00A | 5wbvB-5f05A:undetectable | 5wbvB-5f05A:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fma | NEUROGENIC LOCUSNOTCH HOMOLOGPROTEIN 1 (Homo sapiens) |
PF00008(EGF)PF07645(EGF_CA) | 3 | HIS A 171GLU A 181ASN A 197 | None CA A1295 (-2.9A) CA A1295 (-3.0A) | 1.01A | 5wbvB-5fmaA:undetectable | 5wbvB-5fmaA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fur | TRANSCRIPTIONINITIATION FACTORTFIID SUBUNIT 2 (Homo sapiens) |
no annotation | 3 | HIS I 593GLU I 570ASN I 599 | None | 0.95A | 5wbvB-5furI:0.9 | 5wbvB-5furI:11.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fyg | CYTOCHROME P450 (Marinobacterhydrocarbonoclasticus) |
PF00067(p450) | 3 | HIS A 412GLU A 350ASN A 346 | None | 0.99A | 5wbvB-5fygA:undetectable | 5wbvB-5fygA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h11 | UNCHARACTERIZEDPROTEIN (Danio rerio) |
PF07393(Sec10) | 3 | HIS A 425GLU A 422ASN A 418 | NoneNone BR A 809 ( 4.7A) | 1.00A | 5wbvB-5h11A:undetectable | 5wbvB-5h11A:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7a | IMMUNOGLOBULING-BINDING PROTEIN A (Staphylococcusaureus) |
no annotation | 3 | HIS C 138GLU C 135ASN C 96 | None | 0.62A | 5wbvB-5h7aC:undetectable | 5wbvB-5h7aC:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hqn | SPHINGOMYELINPHOSPHODIESTERASE (Mus musculus) |
PF00149(Metallophos) | 3 | HIS A 317GLU A 318ASN A 381 | PO4 A 710 (-3.7A)NoneNone | 0.90A | 5wbvB-5hqnA:undetectable | 5wbvB-5hqnA:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hvn | 3-DEHYDROQUINATESYNTHASE (Francisellatularensis) |
PF01761(DHQ_synthase) | 3 | HIS A 264GLU A 72ASN A 152 | NAD A 401 ( 4.6A)NAD A 401 (-2.6A)NAD A 401 (-3.5A) | 0.68A | 5wbvB-5hvnA:undetectable | 5wbvB-5hvnA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i85 | SPHINGOMYELINPHOSPHODIESTERASE (Homo sapiens) |
PF00149(Metallophos) | 3 | HIS A 319GLU A 320ASN A 383 | PC A 727 (-3.7A)NoneNone | 0.94A | 5wbvB-5i85A:2.2 | 5wbvB-5i85A:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ijz | NADP-SPECIFICGLUTAMATEDEHYDROGENASE (Corynebacteriumglutamicum) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 3 | HIS A 25GLU A 23ASN A 102 | None | 0.89A | 5wbvB-5ijzA:0.1 | 5wbvB-5ijzA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iry | DESMOCOLLIN-1 (Homo sapiens) |
PF00028(Cadherin) | 3 | HIS A 142GLU A 69ASN A 12 | None CA A 614 ( 2.9A) CA A 605 ( 3.9A) | 0.89A | 5wbvB-5iryA:undetectable | 5wbvB-5iryA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iry | DESMOCOLLIN-1 (Homo sapiens) |
PF00028(Cadherin) | 3 | HIS A 253GLU A 179ASN A 120 | None CA A 616 ( 2.6A) CA A 615 (-2.2A) | 0.94A | 5wbvB-5iryA:undetectable | 5wbvB-5iryA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j55 | CAROTENOID OXYGENASE (Novosphingobiumaromaticivorans) |
PF03055(RPE65) | 3 | HIS A 284GLU A 418ASN A 122 | FE A 501 ( 3.3A)NoneNone | 1.02A | 5wbvB-5j55A:undetectable | 5wbvB-5j55A:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kja | APOCAROTENOID-15,15'-OXYGENASE (Synechocystissp. PCC 6803) |
PF03055(RPE65) | 3 | HIS A 304GLU A 426ASN A 137 | FE2 A 502 (-3.8A)NoneNone | 0.90A | 5wbvB-5kjaA:undetectable | 5wbvB-5kjaA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ldf | GLUTAMINE SYNTHETASE (Salmonellaenterica) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 3 | HIS A 269GLU A 212ASN A 264 | None | 0.98A | 5wbvB-5ldfA:undetectable | 5wbvB-5ldfA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uj6 | GLYCOSYL HYDROLASESFAMILY 2, SUGARBINDING DOMAINPROTEIN (Bacteroidesuniformis) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF11721(Malectin)PF16355(DUF4982) | 3 | HIS A 329GLU A 526ASN A 425 | NoneGOL A 901 (-2.2A)GOL A 901 (-3.2A) | 1.00A | 5wbvB-5uj6A:undetectable | 5wbvB-5uj6A:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v4b | F-BOX/WDREPEAT-CONTAININGPROTEIN 7 (Homo sapiens) |
PF00400(WD40)PF12937(F-box-like) | 3 | HIS B2359GLU B2328ASN B2635 | None | 0.95A | 5wbvB-5v4bB:undetectable | 5wbvB-5v4bB:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6az6 | GNTR FAMILYTRANSCRIPTIONALREGULATOR (Streptococcusagalactiae) |
no annotation | 3 | HIS A 212GLU A 102ASN A 167 | None | 0.94A | 5wbvB-6az6A:undetectable | 5wbvB-6az6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bo6 | - (-) |
no annotation | 3 | HIS A 309GLU A 516ASN A 424 | NoneE0V A 701 (-2.6A)E0V A 701 (-3.3A) | 1.02A | 5wbvB-6bo6A:undetectable | 5wbvB-6bo6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c5c | 3-DEHYDROQUINATESYNTHASE (Candidaalbicans) |
no annotation | 3 | HIS A 280GLU A 80ASN A 159 | NoneNAD A 401 (-2.7A)NAD A 401 (-3.2A) | 0.78A | 5wbvB-6c5cA:undetectable | 5wbvB-6c5cA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c66 | CRISPR-ASSOCIATEDHELICASE, CAS3FAMILY (Thermobifidafusca) |
no annotation | 3 | HIS G 74GLU G 69ASN G 50 | None | 0.98A | 5wbvB-6c66G:undetectable | 5wbvB-6c66G:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6erc | PEROXINECTIN A (Dictyosteliumdiscoideum) |
no annotation | 3 | HIS A 87GLU A 86ASN A 375 | None | 1.02A | 5wbvB-6ercA:1.4 | 5wbvB-6ercA:undetectable |